はてなキーワード: First Impressionとは
35歳、健康診断オールA、脳の20%、右大脳中大脳動脈の梗塞 との記載
→ 右 MCA m1 distal の embolic stroke ?(穿通枝は spare )
脳梗塞は大きく
塞栓性
そのほか
に分けられる(このほかにも分類があるが)。
実際にはアテローム性+塞栓性みたいなものもあり、こんなにクリアカットには分けられない。
35歳と若いことから、今後の人生で再発する危険性は十分にあるし、それを防ぐことがすごく大事。
ご本人は自分のことをすごく不幸と思ってらっしゃる(かどうかは知らんけど)かもだけど、幸運な要素もあったなと思う。
というのは梗塞が右だったということ。
これが左なら失語が残り、言語的コミュニケーションが不可能になっていた可能性が高い。
将来的にそういった事態を防ぎたい。それには原因を知らなきゃいけないわけだ。そのためのタイプ分け。
で、タイプ分け。おそらく塞栓性ですよね。
まず高血圧性の脳梗塞は高齢者に多いし、健康診断で基礎疾患がないとされているので、高血圧は否定的。
アテローム血栓性も、健康診断でオールAとのことで否定的。これは高脂血症(脂質異常症)+高齢+喫煙などでリスクが増えるので。
塞栓性梗塞の原因検索については経食道(けいしょくどう)エコーがなされたとのこと。
これは、食道側から行う心臓の超音波検査。通常の、体表(胸の前に)プローブを当てて行う心臓超音波検査(ガチ勢は「心エコー図」と呼ぶらしい)と比べ、より左心房が詳しく見える。
これで、左心耳血栓(発作性心房細動 Paroxysmal atrial fibrillation, Paf と関連)と卵円孔開存(patent foramen ovale, PFO)は除外したのだろうね?
ただ、ワンポイントの経食エコーで Paf や PFO を完全に除外できるとは限らない。ホルター心電図をやった記載がないし、他にも色んな原因を除外した記録がないよね。
DVT検索をした記載はないし、来院時の D-dimer/FDP (でぃーだいまー、えふでぃーぴー)なども書いていない。
どこまで何をやったのか分からん。
症状的には左片麻痺、同領域の感覚障害。高次脳機能障害かな? 右内包後脚/放線冠/中心前回・後回の広範囲 のどこかが侵されている可能性が高いと。
視野障害が出現しているので、視放線が部分的に侵されている。右側頭葉が冒されている、と。
最終的に感覚障害が残ったが、運動障害は軽い → 内包後脚ではなさそう。放線冠でやられたわけでもなく、脳皮質側でやられた印象を受ける。
脳の20%が失われた → MCA m2 inferior trunk 側で梗塞が大きかったタイプですかね? m2 は inferior が一番広いからねぇ。
脳の20% はやられたってことだけど、結構大きな梗塞だよね。
脳は左右の大脳半球、小脳、脳幹、間脳などに分かれ、左右の大脳半球がそれぞれ40% ぐらいを占めている。脳の20% っていうのは右大脳半球の半分くらいがやられたとのこと。それなら 右MCA領域のほぼ全域がやられているよね。となると、m1 occlusion の可能性が高い。あるいは、m2 の 3枝全てが詰まったか。
m1 occlusion については proximal と distal があるのだけど、
減圧開頭を行ってない
m1 proximal 「らしくない」
→ m1 distal または m2 の複数領域の梗塞(特に inferior trunk に強い:視野障害が出た、感覚障害が残ったなどから)と推察できる。
こういった比較的太い場所への塞栓が起きるには、比較的大きな塞栓が飛ぶ必要があり、つまり Paf とか PFO がある可能性が高いよね。
微小塞栓性のもの、例えばトルーソー症候群とかseptic emboli、fat embolizationみたいな、は否定できる。
大きな塞栓子と言うことでは Paf が隠れてる可能性はあるし、
大きな梗塞の割に運動機能が回復していることから、PFO による DVT の奇異性塞栓だった(比較的"若い"血栓のため、早くに溶けてくれた)のかもしれない。
これらは鑑別の上位に上がるよね。
この方が、以前私の働いていた病院のSCUに入っていたら、ホルター心電図、下肢エコーでのDVT除外、そのほかよく分からない検索もねちっこくやられていたと思う。
自分は専門外なので知らんけど。
アスピリン、チクロピジン、ワーファリン、NOAC/DOACあたり飲んでるのかな?
何かしら飲んでてもおかしくないと感じるが(医療情報が不確かなため、なんとも言えない)。
脳卒中、脳梗塞ってあまりにも頻度が高い疾患だから、いろんな病院、お医者さんが見ていて、その中には脳梗塞診療にしつこくない方も結構おられるんですよね。
「とりあえず点滴2Lだして、ラジカット落としといて」みたいな。
今回総合病院ということから、一定の質の高い医療は受けられているとは思うんだけれども。
脳卒中専門の医師にネチネチと原因検索をしてもらった方がいいんじゃないかなと思います。
やってないならね。やってるかもしれん、分からんが。
次の文章をChatGPTに投げてみた。「35歳男性、基礎疾患なし。右 mca m1 distal occlusion による塞栓性脳梗塞。背景疾患は何だと思う? paf、PFOについてどう思う? 経食道エコー異常なし、ただしDVT検査したか不明。 それでもpaf/PFOはあり得る? その可能性はどの程度? 根拠も含めて。」
回答のサマリーは:
| 4. 総合的推定 | |||
| 疾患 | あり得るか | 推定確率(臨床感覚) | コメント |
| PAF | ○ | 5–10% | 長期モニター推奨(CRYSTAL-AFに基づく) |
| PFO(奇異性塞栓) | ○ | 20–30% | 若年・塞栓性パターンではもっとも典型 |
| 解離 | △ | <10% | 画像で否定されていれば低い |
| 抗リン脂質抗体症候群など | △ | 数% | 血液検査で除外必要 |
| その他(悪性腫瘍など) | △ | <5% | 年齢的に稀 |
だった。
良かったら ChatGPT や GEMINI, Claude なんかに文章を投げて、試してみてくれ。
(解離:発症時に頭痛・頚部痛などがなかったし、MCA解離は非常にまれだし鑑別に入らないでしょう)
https://anond.hatelabo.jp/20251030084205
https://anond.hatelabo.jp/20251030123317
とのこと、
であればこそ、「特発性(とくはつせい、原因不明なこと。cryptogenic)」で片付けず、原因・背景疾患を究明した方が良いんではないか。
なお
PFO+DVTによる奇異性塞栓:カテPFO閉鎖
という予防治療がございます。「朝、シャワーを浴びた時に発症」ってのも、Paf、奇異性塞栓に合致するエピソードだよね。
抗リン脂質抗体症候群など膠原病系にもそれなりの治療があるし…
ずっと元気で居られることを願っています。
Let’s face it: starting a conversation on a dating app can feel terrifying. You see someone you’re interested in, you type out a message, and then… you delete it. “Is this too boring?” “Will they even respond?” “What if I sound awkward?”
We’ve all been there. That first message can make or break your chances of connecting with someone amazing. But here’s the good news: you don’t have to overthink it. With the right opening line, you can spark a conversation that feels natural, fun, and meaningful.
At MixerDates, we believe that every great connection starts with a great conversation. That’s why we’ve put together this guide to help you craft the best dating app opening lines—ones that stand out, show your personality, and lead to real connections. Ready to ditch the “hey” and start making an impact? Let’s dive in!
[:contents]
Before we get into the best opening lines, let’s talk about why your first message is so important.
Your opening line is your chance to make a great first impression. It’s the gateway to a conversation that could lead to something special. A thoughtful, creative message shows that you’re genuinely interested—not just swiping mindlessly.
Your first message sets the tone for the entire conversation. A boring or generic opener might lead to a dull chat, while a fun or intriguing one can spark excitement and curiosity.
Let’s be real: everyone loves feeling special. When you put effort into your opening line, it shows that you care enough to stand out. And on MixerDates, where we value authenticity and positivity, that effort goes a long way.
Now, let’s get to the good stuff—the best dating app opening lines that actually work. These are divided into categories to suit different personalities and situations.
While the examples above are great starting points, the best opening lines are the ones that feel authentic to you. Here are some tips to help you craft your own:
Reference something from their profile—a photo, a hobby, or a shared interest. It shows you’re paying attention and not just copying and pasting.
Avoid heavy or overly serious topics right off the bat. Keep the tone light and playful to make the conversation enjoyable.
Don’t try to be someone you’re not. If you’re naturally funny, lean into that. If you’re more thoughtful, go for a sincere compliment or question.
“Hey” or “What’s up?” might be easy, but they’re also forgettable. Put in a little effort to stand out.
This gives the other person an easy way to respond and keeps the conversation flowing.
At MixerDates, we’re all about creating a positive, inclusive space where you can feel comfortable being yourself. Here’s why our platform is the best place to put these opening lines into practice:
We welcome everyone, no matter who you are or who you love. Our platform is designed to be a safe space where you can connect with like-minded people.
Our users create detailed profiles that make it easy to find shared interests and craft personalized opening lines.
We encourage our community to be genuine and kind, so you can feel confident starting conversations without fear of judgment or rejection.
Don’t just take our word for it—here’s what one of our users had to say:
“I met my partner on MixerDates, and it all started with a simple message about our shared love for travel. The conversation flowed naturally, and the rest is history. I’m so grateful for this platform!”
While a great opening line can spark a conversation, building a real connection takes more than just a clever message. Here are the key elements to look for when seeking a meaningful connection:
A strong connection starts with alignment on the things that matter most. Do you share similar values, life goals, or visions for the future?
Look for someone who is willing to share their thoughts, feelings, and vulnerabilities—and who encourages you to do the same.
Healthy relationships are a two-way street. Both people should be putting in effort to communicate, plan dates, and support each other.
A true connection allows both people to be themselves without judgment. Look for someone who celebrates your uniqueness and encourages you to pursue your passions.
Communication is the foundation of any strong relationship. A mutual connection thrives on honesty, transparency, and the ability to resolve conflicts in a healthy way.
At MixerDates, we’re here to help you find these key elements in a partner. Our platform is designed to connect you with people who share your values and are looking for the same things you are. Starting a conversation on a dating app doesn’t have to be stressful. With the right opening line, you can spark a connection that feels natural, fun, and meaningful. And at MixerDates, we’re here to help you every step of the way.
So, what are you waiting for? Craft that perfect opening line, join MixerDates, and start connecting with people who value authenticity and positivity. Your perfect match is out there—and they’re just one message away.
First dates can be exciting and nerve-wracking all at once. You’re meeting someone new, learning about their interests, and trying to figure out if there’s chemistry between you. And then there’s flirting, that delicate dance of showing someone you’re interested without being too forward or awkward.
Flirting doesn’t have to be a high-pressure situation. In fact, it can be the most fun part of getting to know someone. Whether you're meeting someone on MixerDates or any other platform, the most important thing is to be genuine, stay calm, and let the connection develop naturally.
If you’ve ever found yourself wondering how to flirt on a first date without feeling uncomfortable, you’re not alone. Everyone has their awkward moments, but the more you understand the art of flirting, the easier it becomes. In this article, we’ll break down how to flirt in a way that feels natural, exciting, and authentic to who you are. So, let's dive in and learn how to make the most of your first date experience—without overthinking it.
When it comes to flirting, confidence is key. But what does it really mean to be confident on a first date? Confidence doesn’t mean you need to be perfect, or even outgoing—it simply means being comfortable in your own skin and showing up as your authentic self.
Have you ever noticed how people are drawn to those who radiate self-assurance? It’s not about bragging or dominating the conversation—it’s about presenting yourself with ease. If you feel good about yourself, it will naturally show. A great smile, good posture, and eye contact can go a long way in making a good first impression.
For instance, think about the last time someone walked into a room and immediately caught your attention—not because they were the most attractive person in the room, but because of their energy. They were confident, they were present, and they made you feel at ease. That’s the kind of confidence you want to project on your date.
When you're confident, you're not worried about saying the perfect thing. Instead, you focus on enjoying the moment, making the other person feel comfortable, and letting the connection happen naturally. That’s the magic of confidence—it allows you to be present, fun, and, most importantly, yourself.
Let’s face it—no one wants to feel like they’re being “worked” or put through a game. That’s why subtlety is such a powerful tool when it comes to flirting. It's all about showing interest without being over-the-top or too obvious.
Flirting doesn’t always mean complimenting someone non-stop or using cheesy pickup lines. In fact, the most successful flirting is the kind that happens behind the scenes—subtle, playful, and lighthearted. Think about the little moments, like a teasing comment about how they always order the same thing at a restaurant or the way you laugh at a silly joke they make.
The key is to find a balance. A simple smile or a playful comment can convey interest without being too much. For example, if your date tells you they love hiking but they tend to get lost easily, you could say something like, “So, you’re telling me you need a personal guide? I could get behind that!” It’s lighthearted, humorous, and most importantly, it keeps the conversation fun without putting too much pressure on the situation.
By keeping it subtle, you allow your date to feel at ease. It takes the pressure off them to be perfect and allows both of you to enjoy the interaction more naturally. Flirting doesn’t need to be a performance—it’s about creating an environment where both of you can feel comfortable and authentic.
Now, let’s talk about something incredibly important in the flirting game: active listening. When we’re on a date, we often get caught up in thinking about what to say next, how we’re coming across, or if we’re being interesting enough. But the best way to make an impression? Truly listening to your date.
Active listening means you’re fully engaged in the conversation, giving your date your full attention and responding thoughtfully. It’s about showing that you care about what they’re saying and that you’re genuinely interested in getting to know them better. When you listen actively, you’re also giving them space to open up, and that can create an immediate connection.
For example, if your date mentions they recently traveled to Japan, instead of simply saying, “That’s cool!” you could follow up with something like, “What was the most memorable experience you had there?” This shows that you’re not just hearing their words but are genuinely curious and invested in their experiences. It’s a great way to build rapport and let them know you’re not just there to impress them—you’re there to connect.
While your words are important, body language often speaks louder than anything you can say. Whether you realize it or not, your body is constantly communicating how you feel. How you sit, stand, and move tells your date whether you’re relaxed, engaged, or distracted.
Small gestures can go a long way in flirting. A light touch on the arm, a subtle lean in when they’re speaking, or maintaining good eye contact—all these body language cues help signal your interest. And the great thing is, when done naturally, these cues can be just as effective as words.
For example, if you’re sitting at a café on your date and you lean in slightly when they’re sharing a funny story, you’re not just showing that you’re interested—you’re inviting them into your space. It’s an invitation to connect further. And when they respond by leaning in too, that’s when the magic happens—the unspoken connection that tells you both that there’s potential for more.
Flirting through body language doesn’t mean making grand gestures or being overly touchy. It’s about being present and showing that you’re engaged with your date in a subtle, but meaningful way.
It’s easy to get caught up in overthinking how to flirt or trying to figure out if your date is into you. But here’s a secret—when you let go of the pressure and allow yourself to have fun, everything flows much more naturally. Flirting on a first date doesn’t need to feel like a test or an assignment. It’s supposed to be a fun, lighthearted experience that sets the stage for more great dates ahead.
When was the last time you had a genuinely fun date? Was it when you were trying too hard to impress, or when you were both laughing, chatting, and enjoying each other's company? Flirting becomes effortless when you're present, enjoying the moment, and letting the connection grow naturally.
Sometimes, it's the small moments—like sharing a laugh or swapping embarrassing stories—that make a first date truly special. When you focus on having fun, you create an environment where both of you can relax, flirt, and let the chemistry grow. That’s the secret to a great date.
One of the best things about using a platform like MixerDates is that it takes the guesswork out of the equation. By connecting with someone who already shares your interests and values, you’ve got a head start on making a real connection. No more swiping through countless profiles hoping for a spark—on MixerDates, you already know there’s something in common.
When you’re already on the same page with your date, flirting comes more easily. There’s less of that awkward, “Are we even on the same wavelength?” feeling, and more of the fun, “Wow, we really click!” vibe. Whether you’re talking about favorite hobbies, movies, or life goals, the conversation flows naturally, making the flirting feel effortless.
If you're looking for a place to meet like-minded people and build genuine connections, MixerDates is the perfect platform. It's a great place to find someone who appreciates you for who you are and who you can naturally flirt with, without the stress.
Flirting on a first date is all about confidence, connection, and fun. When you let go of the pressure and focus on enjoying the experience, the chemistry will naturally follow. Remember, the best way to flirt is by being yourself—let your personality shine through, listen with intention, and embrace the moment.
And if you’re ready to meet someone new, who’s just as interested in making a connection as you are, MixerDates is the perfect place to start. So go ahead, take the leap, and see where it leads. Who knows? Your next great connection might be just a click away.
Sign up for MixerDates today and start your journey to exciting first dates and meaningful connections!
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paradise
An ideal or idyllic place or state.
utopia
An imagined place or state of things in which everything is perfect.
from my first impression, utopia is more of an ideal state, political, architectural, philsophical...etc
while paradise is more of state of mind or drug related...
any thoughts?
https://archinect.com/forum/thread/89996/what-is-the-difference-between-paradise-utopia
うーん。