Spiders Cafe is the name of two desert-based saloons, both operated by "Poison Spider" Zala—under the name of Paula—and tied to Baroque Works.
The original location, based in Arabasta, served as an outpost for agents prior to Operation Utopia; its successor, known as the New Spiders Cafe (NEWスパイダーズカフェ,Niyū Supaidāzu Kafe?)[1][2] and formed in a refurbished building on an unknown island after the syndicate's collapse, is a legitimate business currently staffed by many ex-members.
The Spiders Cafe was originally located on Arabasta and was operated by Miss Doublefinger alone under the alias of Paula. Baroque Works used this as meeting place for the Officer Agents before their attempt to take over Arabasta. During the meeting, Mr. 1 and Mr. 2 had a fight which resulted in holes in the wall and other damage to the building. After Baroque Work's defeat and arrest, the location was presumably abandoned.