Mebanazin

Mebanazin
(IUPAC) ime
	1-feniletilhidrazin
Klinički podaci
Identifikatori
CAS broj	65-64-5
ATC kod	nije dodeljen
PubChem	6179
ChemSpider	5944
UNII	Z5R55CJ4CG
ChEMBL	CHEMBL1909283
Hemijski podaci
Formula	C8H12N2
Mol. masa	136,19 g/mol
SMILES	eMolekuli & PubHem
InChI
	InChI=1S/C8H12N2/c1-7(10-9)8-5-3-2-4-6-8/h2-7,10H,9H2,1H3; Key: HHRZAEJMHSGZNP-UHFFFAOYSA-N
Farmakoinformacioni podaci
Trudnoća	?
Pravni status	℞ Prescription only
Način primene	Oralno

Mebanazin (Actomol) je inhibitor monoaminske oksidaze (MAOI) iz hidrazinske hemijske klase, koji je ranije korišten kao antidepresiv tokom 1960-tih, ali je njegova primena prekinuta.^[5]^[6]^[7]

Reference

↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit
↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.
↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. edit
↑ Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). „ChEMBL: a large-scale bioactivity database for drug discovery”. Nucleic Acids Res 40 (Database issue): D1100-7. DOI:10.1093/nar/gkr777. PMID 21948594. edit
↑ Gilmour SJ (September 1965). „Clinical trial of mebanazine--a new monoamine oxidase inhibitor”. The British Journal of Psychiatry : the Journal of Mental Science 111 (478): 899–902. PMID 5889715.
↑ Barker JC, Jan IA, Enoch MD (November 1965). „A controlled trial of mebanazine ('Actomol') in depression”. The British Journal of Psychiatry : the Journal of Mental Science 111 (480): 1095–100. PMID 5320546.
↑ Knott F (1965). „A preliminary trial of mebanazine in depressive states”. The Journal of New Drugs 5 (6): 345–7. PMID 5327282. Arhivirano iz originala na datum 2019-12-15. Pristupljeno 2014-04-05.

Povezano

Hidrazin (antidepresiv)

Spoljašnje veze

	Portal Medicina
	Portal Hemija

[1] Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit

[2] Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.

[3] Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. edit

[4] Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). „ChEMBL: a large-scale bioactivity database for drug discovery”. Nucleic Acids Res 40 (Database issue): D1100-7. DOI:10.1093/nar/gkr777. PMID 21948594. edit

[pmid5889715-5] Gilmour SJ (September 1965). „Clinical trial of mebanazine--a new monoamine oxidase inhibitor”. The British Journal of Psychiatry : the Journal of Mental Science 111 (478): 899–902. PMID 5889715.

[pmid5320546-6] Barker JC, Jan IA, Enoch MD (November 1965). „A controlled trial of mebanazine ('Actomol') in depression”. The British Journal of Psychiatry : the Journal of Mental Science 111 (480): 1095–100. PMID 5320546.

[pmid5327282-7] Knott F (1965). „A preliminary trial of mebanazine in depressive states”. The Journal of New Drugs 5 (6): 345–7. PMID 5327282. Arhivirano iz originala na datum 2019-12-15. Pristupljeno 2014-04-05.

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