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We begin with a series of microinjections into the subject's major muscle groups. The serum infusion will cause immediate cellular change. And then, to stimulate growth, the subject will be saturated with Vita-Rays.
Abraham Erskine explaining how the serum works.

The Super Soldier Serum is a chemical formula from Marvel Comics.

History[]

The Super Soldier Serum was created by the brilliant scientist Abraham Erskine, it grants the ones who inject themselves with amazing powers.

Steve Rogers volunteered for a secret government project that revolved around injecting him with the Super Soldier Serum, which gave him superhuman strength and invulnerability, thus he became Captain America.

Johann Schmidt injected himself with the Super Soldier Serum. However, since he injected himself with an earlier version of the formula, he suffered side effects and became the monstrous Red Skull. Wilfred Malick was tasked with delivering one of the serum's ingredients, for HYDRA.

Bucky Barnes was injected with the Super Soldier Serum by Arnim Zola as part of the process that created his "Winter Soldier" persona.

The U.S. soldier, Isaiah Bradley, secretly took the serum and became a Super Soldier, and was later sent to confront Bucky Barnes in the Korean War. After the war, he was imprisoned for 30 years and members of HYDRA experimented on him, runing tests with his blood and cells. The samples of Isaiah's blood were later obtained by the CIA.

Bucky, in his Winter Soldier persona, was sent to retrieve packets of the Super Soldier Serum that were recreated by Howard Stark, the night he killed Howard and his wife, Maria Stark. HYDRA then used these packets to create more Winter Soldiers.

The Super Soldier Serum was used as part of the Centipede Project.

Emil Blonsky injected himself with the Super Soldier Serum to be a match for the Hulk. However, he also injected himself with Hulk's gamma radiation-enhanced blood, which backfired when Emil transformed into the reptilian monstrosity known as the Abomination.

Many years later, it is revealed that a scientist called Wilfred Nagel was able to recreate the serum. Nagel was initially hired by HYDRA during the Winter Soldier program and later by the CIA to work with the samples obtained from Isaiah. Nagel managed to recreate a more subtle and optimised version of the serum's formula. However, a group called Flag Smashers led by Karli Morgenthau stole the 20 vials Nagel made. The Flag Smashers consumed 8 of the vials, acquiring Super Soldier powers, but 11 of the vials were later destroyed by Baron Zemo. The last serum was taken by the U.S. agent John Walker, who injected himself with it to become stronger as the new Captain America. After injecting himself, Walker became mentally unstable. As result, upon confronting the Flag Smashers, Walker brutally murdered one of them, Nico, to avenge the death of his partner at the hands of Karli.

Red Guardian was injected with the Super Soldier Serum, giving him superhuman strength and durability. Many years later, in 2024, John Walker injected himself with the serum after becoming the next Captain America and vowing revenge on Karli Morgenthau for his friend's death. John found vile's of the serum and injected himself before destroying the rest of them so they can't ever be used again.

The serum was featured in the animated series, What If...?, in an alternate reality, where Peggy Carter was given it instead of Steve Rogers as he was injured. Just like Steve, Peggy was given superhuman abilities such as strength as a result.

External Links[]

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Phil CoulsonMelinda MayGrant WardDaisy Johnson/QuakeLeo FitzJemma SimmonsLance HunterMockingbirdHiveAlphonso MackenzieLincoln CampbellHolden RadcliffeYo-YoDeke ShawJohn GarrettMichael PetersonFranklin HallAce PetersonChan Ho YinVictoria HandAkela AmadorRainaElliot RandolphLoreleiAudrey NathanAgent KoenigAntoine TriplettAbsorbing ManSunil BakshiAngar the ScreamerAgent 33Daniel WhitehallCalvin ZaboRobert GonzalesGordonAidaJohnny Blaze/Ghost RiderRobbie Reyes/Ghost RiderPatriotKasiusSinaraIzelPhil Coulson (LMD)Freddy MalickErnest KoenigViolaSibylNathaniel MalickKoraEllen NadeerChristian WardBlizzardDoctor ListPresident Matthew EllisFlintVin-TakJiayingSuperiorGideon MalickRuby Hale
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Season One: "Pilot" • "0-8-4" • "The Asset" • "Eye Spy" • "Girl in the Flower Dress" • "FZZT" • "The Hub" • "The Well" • "Repairs" • "The Bridge" • "The Magical Place" • "Seeds" • "T.R.A.C.K.S." • "T.A.H.I.T.I." • "Yes Men" • "End of the Beginning" • "Turn, Turn, Turn" • "Providence" • "The Only Light in the Darkness" • "Nothing Personal" • "Ragtag" • "Beginning of the End"

Season Two: "Shadows" • "Heavy is the Head" • "Making Friends and Influencing People" • "Face My Enemy" • "A Hen in the Wolf House" • "A Fractured House" • "The Writing on the Wall" • "The Things We Bury" • "...Ye Who Enter Here" • "What They Become" • "Aftershocks" • "Who You Really Are" • "One of Us" • "Love in the Time of HYDRA" • "One Door Closes" • "Afterlife" • "Melinda" • "The Frenemy of My Enemy" • "The Dirty Half Dozen" • "Scars" • "S.O.S."
Season Three: "Laws of Nature" • "Purpose in the Machine" • "A Wanted (Inhu)man" • "Devils You Know" • "4,722 Hours" • "Among Us Hide..." • "Chaos Theory" • "Many Heads, One Tale" • "Closure" • "Maveth" • "Bouncing Back" • "The Inside Man" • "Parting Shot" • "Watchdogs" • "Spacetime" • "Paradise Lost" • "The Team" • "The Singularity" • "Failed Experiments" • "Emancipation" • "Absolution" • "Ascension"
Season Four: "The Ghost" • "Meet the New Boss" • "Uprising" • "Let Me Stand Next to Your Fire" • "Lockup" • "The Good Samaritan" • "Deals With Our Devils" • "The Laws of Inferno Dynamics • "Broken Promises" • "The Patriot" • "Wake Up" • "Hot Potato Soup" • "BOOM" • "The Man Behind the Shield" • "Self Control" • "What If..." • "Identity and Change" • "No Regrets" • "All the Madame's Men" • "Farewell, Cruel World!" • "The Return" • "World's End"
Season Five: "Orientation" • "A Life Spent" • "A Life Earned" • "Rewind" • "Fun & Games" • "Together or Not at All" • "The Last Day" • "Best Laid Plans" • "Past Life" • "All the Comforts of Home" • "The Real Deal" • "Principia" • "The Devil Complex" • "Rise and Shine" • "Inside Voices" • "The Honeymoon" • "All Roads Lead..." • "Option Two" • "The One Who Will Save Us All" • "The Force of Gravity" • "The End"
Season Six: "Missing Pieces" • "Window of Opportunity" • "Fear and Loathing on the Planet of Kitson" • "Code Yellow" • "The Other Thing" • "Inescapable" • "Toldja" • "Collision Course (Part I)" • "Collision Course (Part II)" • "Leap" • "From the Ashes" • "The Sign" • "New Life"
Season Seven: "The New Deal" • "Know Your Onions" • "Alien Commies from the Future!" • "Out of the Past" • "A Trout in the Milk" • "Adapt or Die" • "The Totally Excellent Adventures of Mack and the D" • "After, Before" • "As I Have Always Been" • "Stolen" • "Brand New Day" • "The End is at Hand" • "What We're Fighting For" •

Objects
Plasma Particle BeamGravitoniumObeliskSuper Soldier SerumBerserker Staff
Vehicles
QuinjetL.O.L.A.S.H.I.E.L.D. Helicarrier
Groups
S.H.I.E.L.D.HYDRAInhumansAsgardiansKreeUnited NationsHowling Commandos
Locations
AtlantisTriskelionChina

v - e - d
What If logo
Media
What If...? (soundtrack 1/2/3) • Marvel Studios: Assembled
Characters
Heroes: Peggy Carter/Captain CarterKahhoriT'Challa/Star-Lord/Black PantherStephen Strange/Doctor Strange/Strange SupremeNick FuryBucky Barnes/Winter SoldierSteve Rogers/HYDRA Stomper/Captain AmericaThor OdinsonClint Barton/HawkeyeNatasha Romanoff/Black WidowBruce Banner/HulkTony Stark/Iron ManVisionSam Wilson/Falcon/Captain AmericaCarol Danvers/Captain MarvelOkoyeNebulaHappy Hogan/FreakGamoraWongT'Chaka/Black PantherHoward the DuckDrax the DestroyerPeter Quill/Star-LordHank Pym/Yellowjacket/Ant-ManScott Lang/Ant-ManPeter Parker/Spider-ManHope van Dyne/WaspWanda Maximoff/Scarlet WitchGrootBill Foster/GoliathWendy Lawson/Mar-VellMonica RambeauAgatha HarknessKingoAlexei Shostakov/Red GuardianMoon KnightRiri Williams/IronheartShang-ChiKate BishopValkyrieYing NanByrdie the DuckOroro Munroe/Storm

Villains: Loki LaufeysonHelaXu WenwuUltronErik KillmongerProxima MidnightEbony MawCorvus GlaiveCull ObsidianArnim ZolaJohann Schmidt/Red SkullSurturThanosCollectorBatrocEgoBatrocGrandmasterUlysses KlaueRonan the AccuserJustin HammerGeneral DreykovZeusKaeciliusMalekithQuentin BeckXu Xialing/The HoodSonny BurchDormammuMelina Vostokoff
Other characters: Uatu/The WatcherJ.A.R.V.I.S.Phil CoulsonThaddeus RossSifVolstaggYondu UdontaBrock RumlowHoward StarkAbraham ErskineDum Dum DuganCarinaKorath the PursuerKraglin ObfonteriTaserfaceChristine PalmerAncient OneJane FosterFriggaHogunFandralHeimdallMaria HillRhodeySharon CarterDarcy LewisQueen RamondaPepper PottsShuriBetty RossCosmo the SpacedogKorgIrani RaelGarthan SaalRavager KPeggy CarterGooseOdin BorsonNakiaEdwin JarvisSarah WilsonMaria StarkJohn Walker

Episodes
Season One: "What If... Captain Carter Were The First Avenger?" • "What If... T'Challa Became a Star-Lord?" • "What If... The World Lost Its Mightiest Heroes?" • "What If... Doctor Strange Lost His Heart Instead of His Hands?" • "What If... Zombies!?" • "What If... Killmonger Rescued Tony Stark?" • "What If... Thor Were an Only Child?" • "What If... Ultron Won?" • "What If... The Watcher Broke His Oath?"

Season Two: "What if... Nebula Joined the Nova Corps?" • "What if... Peter Quill Attacked Earth's Mightiest Heroes?" • "What if... Happy Hogan Saved Christmas?" • "What if... Iron Man Crashed Into the Grandmaster?" • "What if... Captain Carter Fought The Hydra Stomper?" • "What if... Kahhori Reshaped the World?" • "What if... Hela Found The Ten Rings?" • "What if... The Avengers Assembled in 1602?" • "What if... Strange Supreme Intervened?"
Season Three: "What If...The Hulk Fought the Mech Avengers?" • "What If...Agatha Went To Hollywood?" • "What If...The Red Guardian Stopped the Winter Soldier?" • "What If...Howard the Duck Got Hitched?" • "What If...The Emergence Destroyed the Earth?" • "What If...1872?" • "What If...The Watcher Disappeared?" • "What If...What If?"

Organizations
S.H.I.E.L.D.Stark IndustriesHYDRAAvengersMasters of the Mystic ArtsBlack OrderGuardians of the GalaxyGuardians of the MultiverseHowling CommandosRavagersNova Corps
Objects
MjölnirOrbPym ParticlesCaptain America's ShieldCloak of LevitationEye of AgamottoScepterSuper Soldier SerumTen RingsTesseractInfinity GauntletInfinity StonesVibraniumAetherUltron SentriesKamala's Bangle
Locations
AsgardNew York CityProject P.E.G.A.S.U.S.Collector's MuseumDark DimensionSakaarSan FranciscoTony Stark's MansionKamar TajKnowhereWakandaXandar
See Also
Frost GiantsSkrullsKreeX-Men Theme

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