The Tissue Level of Organization: Powerpoint® Lecture Slides Prepared by Jason Lapres Lone Star College - North Harris
The Tissue Level of Organization: Powerpoint® Lecture Slides Prepared by Jason Lapres Lone Star College - North Harris
The Tissue Level of Organization: Powerpoint® Lecture Slides Prepared by Jason Lapres Lone Star College - North Harris
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The Tissue
Level of
Organization
PowerPoint® Lecture Slides
prepared by Jason LaPres
Lone Star College - North Harris
Epithelia
Layers of cells covering internal or external
surfaces
Glands
Structures that produce secretions
Characteristics of Epithelia
Cellularity (cell junctions)
Polarity (apical and basal surfaces)
Attachment (basal lamina)
Avascularity
Regeneration
Intercellular Connections
Support and communication
CAMs (cell adhesion molecules):
– transmembrane proteins
Intercellular cement:
– proteoglycans
Intercellular Connections
Cell junctions
Form bonds with other cells or extracellular material:
– occluding (tight) junctions
– gap junctions
Intercellular Connections
Based on layers
Simple epithelium: single layer of cells
Stratified epithelium: several layers of cells
Squamous Epithelia
Simple squamous epithelium
Absorption and diffusion
Mesothelium
Lines body cavities
Endothelium
Lines heart and blood vessels
Squamous Epithelia
Stratified squamous epithelium
Protects against attacks
Cuboidal Epithelia
Simple cuboidal epithelium
Secretion and absorption
Transitional Epithelium
Tolerates repeated cycles of stretching and recoiling
and returns to its previous shape without damage
Appearance changes as stretching occurs
Columnar Epithelia
Simple columnar epithelium
Absorption and secretion
Glandular Epithelia
Endocrine glands
Release hormones:
– into interstitial fluid
– no ducts
Exocrine glands
Produce secretions:
– onto epithelial surfaces
– through ducts
Glandular Epithelia
Types of secretions
Serous glands:
– watery secretions
Mucous glands:
– secrete mucins
Glandular Epithelia
Gland structure
Unicellular glands
– Mucous (goblet) cells are the only unicellular
exocrine glands:
» scattered among epithelia
» for example, in intestinal lining
Glandular Epithelia
Gland structure
Multicellular glands:
– structure of the duct:
» simple (undivided)
» compound (divided)
– shape of secretory portion of the gland:
» tubular (tube shaped)
» alveolar or acinar (blind pockets)
– relationship between ducts and glandular areas:
» branched (several secretory areas sharing one
duct)
Fibroblasts Melanocytes
Fibrocytes Mast cells
Macrophages Lymphocytes
Adipocytes Microphages
Mesenchymal cells
Fibrocytes
The second most abundant cell type:
– found in all connective tissue proper
– maintain the fibers of connective tissue proper
Mast Cells
Stimulate inflammation after injury or infection:
– release histamine and heparin
Microphages
Phagocytic blood cells:
– respond to signals from macrophages and mast cells
Ground Substance
Is clear, colorless, and viscous
Areolar Tissue
Least specialized
Open framework
Viscous ground substance
Elastic fibers
Holds blood vessels and capillary beds
For example, under skin (subcutaneous layer)
Adipose Tissue
Adipose cells
Adipocytes in adults do not divide:
– expand to store fat
– shrink as fats are released
Mesenchymal cells divide and
differentiate:
– to produce more fat cells
– when more storage is needed
Reticular Tissue
Provides support
Reticular organs
Spleen, liver, lymph nodes, and bone marrow
Elastic tissue
Elastic Tissue
Made of elastic fibers
For example, elastic ligaments of spinal vertebrae
– platelets
Interstitial fluid
Lymph
Lymph
Extracellular fluid
Collected from interstitial space
Bone
Calcified (made rigid by calcium salts, minerals)
Cartilage Matrix
Proteoglycans derived from chondroitin sulfates
Cartilage Structure
No blood vessels:
Perichondrium:
Membranes
Are physical barriers
Consist of
An epithelium
Serous membranes
Cutaneous membrane
Synovial membranes
Lamina propria
Is areolar tissue
Serous Membranes
Line cavities not open to the outside
Are thin but strong
Have fluid transudate to reduce friction
Have a parietal portion covering the cavity
Have a visceral portion (serosa) covering the
organs
Cutaneous membrane
Is skin, surface of the body
Thick, waterproof, and dry
Synovial membranes
Line moving, articulating joint cavities
Produce synovial fluid (lubricant)
Protect the ends of bones
Lack a true epithelium
Deep fascia
Subserous fascia
Do not divide
Spinal cord
Neuroglia
Supporting cells
Dendrites
Short branches extending from the cell body
Receive incoming signals
Regeneration
Inflammatory Response
Can be triggered by
Trauma (physical injury)
Regeneration
When the injury or infection is cleaned up
Healing (regeneration) begins
Hormonal alterations
Effects of Aging
Chemical and structural tissue changes
Thinning epithelia and connective tissues
Increased bruising and bone brittleness
Joint pain and broken bones
Cardiovascular disease
Mental deterioration