c.

AlO2
MODULE 1 (Q &A) d.Al2O3

1.This is added to glass to increase the refractive 11.the ff. are true regarding methenamine except:
index? a. It is use internally as urinary antiseptic.
a.MnO2 b. the free base has no bacteriostatic power
b. Boron c.to optimize the antibacterial effect, an alkalinizing
c. Pb agent generally accompanies the administration of
d. potassium methenamine
d. Its activity depends on the liberation of
2.Process for the production of ammonia? formaldehyde.
a.haber process
b.contact process 12.this is the first element produced artificially
c. wohler process a.Tc
d. solvay process b.Rb
c.Cs
3. the mechanism of action in the use of carbon as d.Ta
anti- diarrheal is:
a. precipitation 13.this type of system does not allow heat flow
b.absorption a. adiabatic
c. adsorption b.closed system
d. oxidation c.Open system
d. diathermal
4.this type of mixture exhibits electrical property
and optical property known as the tyndall effect? 14.Stabilizer used for hydrogen peroxide topical
a.emulsiom solution:
b. colloid a. Oxybenzone
c.suspension b.Acetanilide
d.solution c.parabens
d. Lithium carbonate
5.the official sulfur ointment contains what
percentage of Sulphur? 15.clotrimazole
a.5% a. Daktarin
b.1% b.Canesten
c.10% c.Bactrim
d.15% d.Nizoral

6.which of the ff. are not strong electrolytes? 16.thenards “ oxygenated acid”
a. C12H22O11 a. H2SO4
b.HC2H3O2 b.H2O2
c. none of the choices c.HNO3
d. all of the choices d.HCl

7.barbiturates containing a sulfur atom are usually: 17.liquified phemol is containing ____ water
a. short acting a.12%
b. ultra short acting b.1%
c.long acting c.19%
d. intermediate acting d.10%

8.Which of the ff. parent drug is incorrectly paired 18. this grouping of elements in the periodic table is
with its active metabolite? based on the number of main energy levels filled by
a. chloral hydrate—trichlorethanol the electrons:
b.mephobarbital—phenobarbital a. Family and group
c.azathioprine—6-mercaptopurine b.Period
d. none of the choices c. Group
d. Family
9. The ff. phase changes releases energy except:
a. solid to liquid 19.which of the ff. is a member of the group V
b. liquid to solid cations ?
c.gas to liquid a.Ba2+
d. liquid to gas b.Fe2+
c.Mg2+
10. considering the number of valence electrons in d.Pb2+
Al and O , what is the expected formula when these
two react to form a compound? 20. which anion forms a blue complex with the
a.AlO2 thiocyanate anion?
b.Al2O a. Au2+

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b.Mn2+ 30.simethicone containing antacids contain as/an:
c.Ag+ a.antacid
d. CO2+ b.antifoaming agent
d.Flavorant
21.large overdose of acetaminophen are likely to e.protective
cause:
a.tinnitus 31.which element is used as a glucose tolerance ?
b.hepatic necrosis a. Cr
c.agranulocytosis b.Mg
d. renal tubular aciodosis c.Mn
d.Si
22.an example of a commercial product that is
prodrug: 32. This element is present in insulin
a.Lasix a. Co
b. Geocillin b.Cu
c.morphine c.Fe
d. Valium d.Mg
e.Zn
23. Drug of choice for leprosy:
a.rifampicin 33. Bordeaux mixture contains what salt?
b.ethonamide a.cupric sulfate
c.prothionamide b. Magnesium sulfate
d. clofazimine c.selenium sulfate
e. dapsone d. silver nitrate

24.compounds that is result from a combination of 34.prostaglandins are also known as:
electron donors with a metal ion to form a ring a. saturated fats
structure. b. compound lipids
a.chelates c.eicosanoids
b. ligands d. all of the choices
c. both
d.none 35.ethylene oxides and propylene oxide are examples
of:
25.this compound is use to disinfect drinking water a.ketone
a.chloroform b.ester
b. halazone c.ether
c. copper sulfate d.alcohol
d. Muriatic acid
36.what is the IUPAC name of valproic acid.
26. this metal produces a bright red crystalline a. 2- propylpentanoic acid
precipitate insoluble in ammonia with b. 2- butylhexanoic acid
dimethylglyoxime reagent: c. 2-methylpropanic acid
a. Citrate d. 2- ethylbutanoic acid
b.Cobalt
c.nickel 37.some of the uses of astringent are :
d.Copper a. anti perspirant
b. caustic
27.mescaline is a _____ derivative c. styptic
a.Steroidal d. all of the choices
b.Indothylamine
c.phenylethylamine 38. The ion that gives positive result to thenards
d.xanthine Blue test:
a. aluminum
28. Halazone is a/an: b.Chroumium
a.iodophor c.manganese
b.mercury containing anti-infective d. zinc
c. chlorine containing anti infectie
d.oxidizing agent 39. the ff. can cause a shift of equilibrium except:
e. none of the above a. catalyst
b.concentration
29.The energy required to remove an electron from a c.pressure
neutral atom is: d.temperature
a.Electrical energy
b.electron affinity 40.they are called the “soluble groups”
c.Ionization potential a. alkali metals
d.Kinetic energy b.alkaline earth metals
c. aluminum iron-group

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d. silver group d.nalidixic acid

41.the isotope used in determination of the volume 51. Mechanism of action of quinolone:
of red blood cells and total blood volume: a.injury to plasma membrane
a. Cr-51 b. inhibition of DNA gyrase
b. Co-58 c.protein synthesis inhibition
c.Fe-59 d.production of toxic free readicals
d.Ra-226
52. 7-chloro-7-deoxy lincomycin:
42.the chemical properties of the elements depend a. clindamycin
upon the extent to which their electrons are: b.spectinomycin
a. replaced c. roxithromycin
b.completed d.ilotycin
c. lost
d.redistributred 53.newest and most potent quinolone derivative for
malaria:
43.an acid which is a proton donor yield a: a. amodiaquine
a. base b.mefloquine
b. salt c.atabrine
c. conjugate base d.daraprim
d.conjugated acid.
54.this anti-burn therapy causes systemic acidosis:
44. all are iodine containing preparations except: a.silvadene
a.betadine b.sulfamylon
b. iodine tincture c.whitfield
c. formol d. vandol
d. Lugol’s solution
55. DOC for filarial infections:
45. a preparation made by incorporating a solution a.ivermectin
of lead subacetate with an ointment base consisting b.praziquantel
of wool fat,white wax, white petroleum and c.diethylcarbamazine
camphor: d.Stibophen
a. white lead
b.Goulards cerate 56. a tumor is benign if:
c.sugar of lead a.metastasis is evident
d. goulards extract b. cell originating from the tumor may invade other
tissues and cause damge
46.most active metallic elements: c. tumor mass may be removed by surgery and
a. alkali metals regression of remaining cells may occur
b.oxidizing agent d. cause damage to surrounding structures.
c. base metals
d. solubilizing agents 57.DOC for absence seizures
a. carbamazepine
47.the radiopharmaceutical that is used for kidney b.ethosuximide
imaging or determining renal function, c.phenytoin]
a. I-131-NaI d.primidone
b.I-131- human serum albumin
c.Tc-99m-Heptagluconate 58.anesthetic of choice for patients with asthma
d.Tc-99m-phytate a. ketamine
b.thiopental
48. a fluoroquinolone : c. enflurane
a.Norfloxacin d.none of the above
b.Pipemedic acid
c.Methenamine 59.the principal hydrolytic degradation product of
d.none of the above aspirin is:
a.methyl salicylate
49. these drugs are used in the treatment of amoebic b.acetyl chloride
dysentery, except: c.salicylic acid
a.tinidazole d. salicylamide
b.chloroquine
c.Etofamide 60. Which of the following is/are true regarding
d.metronidazole phase I drug metabolism?
I. Also known as conjugation reaction
50.first gen. urinary tract anti-infective II. Includes oxidation, reduction, hydrolysis
a.salicylic acid III. Generally tends to provide a functional group or
b.griseofulvin “handle” to the molecule
c.Norfloxacin

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a. I, II and III b. griseofulvin
b. I and II only c. natamycin
c. I only d. candicidin
d. II and III only e. amphotericin B
e. I and III only
68. A polyene antibiotic first isolated in 1951 from a
61. Which of the following is/ are considered slow strain of Streptomyces noursei by Hazen and Brown
acetylators? a. Nystatin
I. Eskimos b. Amphotericin B
II. Egyptians c. Natamycin
III. Filipinos d. Candicidin
IV. Mediterranean Jews e. Griseofulvin

a. III only 69. A series of synthetic antibacterial agents

b. I and II only patterned after nalidixic acid, with an effective
c. III and IV only antibacterial spectrum largely confined to gram-
d. I and III only negative bacteria
e. II and IV only a. substituted imidazoles
b. polyenes
62. The biotransformation of chloral hydrate via c. biguanides
aldehyde reduction forms d. dihydrotriazines
a. Desipramine e. quinolones
b. Mesoridazine
c. Trichloroethanol 70. One who led the isolation of streptomycin from
d. Sulindac Streptomyces griseus:
e. 6-Mercaptopurin a. Pasteur and Joubert
b. Waksman
63. Which of the following is/are parent drug/s? c. Vullemin
I. Digitoxin d. Florey and Chain
II. Hydrocortisone e. Alexander Fleming
III. Primidone
IV. Propranolol 71. Benzylpenicillin binds preferentially to:
a. PBPs 1a and 1b
a. I and II only b. PBP 2
b. III and IV only c. PBP 3
c. I, II, and III only d. PBPs 4 to 6
d. I, III and IV only e. PBP 6
e. I, II, III and IV
72. These are the major antigenic determinants that
64. Ethanol that has been rendered unfit for use in are formed when penicillins or its rearrangement
intoxicating beverages by the addition of other products in vivo react with lysine-ɛ-amino groups of
substances proteins resulting to allergic reactions.
a. Denaturated alcohol a. Penicillanic acid
b. Wood alcohol b. Penicilloyl proteins
c. Isopropyl alcohol c. Penicillanic proteins
d. Formaldehyde d. Penicillanic acids
e. Glutarol e. Penams

65. . A preparation of 5% iodine in water with 73. Primaxin is a combination of:

potassium iodide I. Tazocillin
a. Iodine solution II. Imipenem
b. Iodine tincture III. Piperacillin
c. Lugol’s solution IV. Cilastatin
d. Mayer’s reagent
e. Wagner’s reagent a. I and II
b. I and III
66. A dye available as vaginal suppositories for the c. II and III
treatment of yeast infection d. II and IV
a. malachite green e. III and IV
b. methylene blue
c. phenolphthalein 74. A parenteral Cephamycin
d. gentian blue a. cefoxitin
e. basic fuchsin b. ceftazidime
c. cephalexin
67. A potent antifungal substance with a polyene d. cefadroxil
structure from Streptomyces nodosus e. cefamandole
a. nystatin

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75. It is known as Streptomycin B 83. This refers to the direct transition of the solid
a. Sreptomycin state to the vapor state
b. Mannisidostreptomycin . A. Deposition
c. Hydroxystreptomycin B. condensation
d. Humatin C. sublimation
e. Paromycin Sulfate, USP D. melting
E. evaporation
76. A group of antibiotics that are derivatives of an
octahydronaphthacene, a hydrocarbon system that 84.This states that orbitals of the same energy will
comprises four annelated six-membered rings. be singly filled first with electrons before they are
a. macrolides paired.
b. tetracyclines A. Aufbau principle
c. lincomycins B. Heisenberg Uncertainly Principle
d. polymixins C. Hund’s rule
e. sulfonamides D. n + I rule
E. Pauli’s Exclusion Principle
77.The first widely used broad spectrum that was
isolated by Ehrlich in 1974 from S.venezuelae 85. Which of the following is a characteristic of the
a. Clindamycin gaseous state?
b. Chloramphenicol, USP A. The molecules move past one another
c. Vancomycin HCl, USP B. its volume is definite
d. Novobiocin Sodium, USP C. Is has definite shape
e. Bleomycin Sulfate D. All of the given
E. The molecules are tightly bonded
78. 7-chloro-7-deoxylincomycin
a. Cleocin 86. These are atoms of the same element having the
b. Unasyn same protons but of different number of neutrons. A.
c. Unipen Isobars
d. Lincocin B. isotopes
e. Ponstan C. Isotones
D. none of the given
79. An antineoplastic drug active against rapidly E. Isomers
proliferating cells in the synthesis phase during
which it prevents the formation of 87. The chemical reaction between an acid and a
deoxyribonucleotides by inhibition of ribonucleotide base that produces salt and water. A. Oxidation
diphosphate reductase. B. Combination
a. Carboplatin C. Reduction
b. Hydroxyurea D. Single replacement
c. Mitoguazone E. Neutralization
d. Hycanthone
e. Doxirubicin 88. Ions found in the extracellular fluid EXCEPT:
A. Phosphate
80. 4-chloro-N-furfuryl-5-sulfamoyl anthranilic acid B. Sodium
is: C. Chloride
a. Bumetanide D. Bicarbonate
b. Furosemide
c. Ethacrynic acid 89. Calcium imparts a _______________color to a
d. Chlorothiazide non-luminous flame.
e. Hydrochlorothiazide A. Crimson red
B. green
81. The water ion theory of acids and bases is C. Carmine red
attributed to: D. brick red
A. Lewis E. Bright yellow
b. Pauling
c. Bronsted 90. Chalybeate water contains:
d. Pearson A. Lithium
e.Arrhenius B. salt
C. Carbon
82. Which of the following properties of matter is D. iron
dependent on the quantity of matter present?
A. Flammability 91.The following statement is/are true regarding the
B. reactivity relationship of bond length and bond polarity except:
C. Volume a. As the bond polarity increase, the bond length
D. density decreases
E. Boiling point b. A C-F bond has a longer bond length than C-C
c. As bond polarity increases the bond length also
increases

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d. A and B only 99. The following factors must be considered in
e. B and C only designing an agonist:
a. The drug must have the correct binding groups.
92. What is the name of the following structure: b. Specific functional groups must be correctly
CH3CH2CH2-C=CH positioned.
a. 1- pentyne c. The size and shape of the drug molecule.
b. N-propylacetylene d. A and B only
c. 4-pentyne e. All of the above
d. 1-pentatriene
e. A and B 100. What is the rate-limiting step in drug
absorption of orally administered solid dosage forms?
93. These lipid soluble compounds are also paraffin a. Dissolution rate
or saturated hydrocarbons. They commonly undergo b. Metabolism rate
halogination and combustion reaction and, in vivo, c. Elimination rate
terminal carbon or side chain hydroxylation may d. A and B only
occur. a. Alkanes e. B and C only
b. Alkenes
c. Aromatic hydrocarbon
d. Alkynes
e. Alkyl halides

94. The structure of these compounds is based on

benzene. These molecules exhibit multicenter
bonding, which confers unique chemical properties.
a. Alkanes
b. Alkenes
c. Aromatic hydrocarbon
d. Alkynes
e. Alkyl halides

95. Which of the following compounds has a general

formula of R-O-R with an oxygen bonded to 2
carbon atoms?
a. Aldehydes
b. Ether
c. Phenols
d. Ketones
e. Esters

96. These compounds have a general formula of

RCOOH and commonly undergo salt formation with
bases, esterification and decaroxylation.
a. Ketones
b. Ether
c. Esters
d. Amides
e. Carboxylic acid

97. Decomposition the drug molecule at room

temperature most likely would occur by
a. Hydrolysis of the ester
b. Reduction of the carboxylic acid
c. Oxidation of the ester
d. A and B only
e. B and C only

98. This is the type of enzyme inhibition where the

drug react with the enzyme and forms a covalent
bond.
a. Reversible inhibition
b. Irreversible inhibition
c. Competitive inhibition
d. Uncompetitive inhibition
e. Non-competitive inhibition

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Answers

1.C 65.C
2.A 66.D
3.C 67.E
4.B 68.A
5.C 69.E
6.D 70.B
7.B 71.C
8.D 72.B
9.C 73.D
10.D 74.A
11.C 75.B
12.A 76.B
13.A. 77.B
14.B 78.A
15.B 79.B
16.D 80.B
17.D 81.E
18.B 82.C
19.C 83.C
20.D 84.C
21.B 85.A
22.A 86.B
23.E 87.C
24.A 88.A
25.A 89.D
26.C 90.D
27.C 91.A
28.C 92.E
29.C 93.A
30.B 94.C
31.A 95.B
32.E 96.E
33.A 97.A
34.C 98.B
35.C 99.E
36.A 100.A
37.D
38.A
39.A YOU DON’T
40.A HAVE TO BE
41.A
42.C GREAT
43.C TO START,
44.C BUT YOU HAVE TO

START
45.B
46.A
47.C TO BE GREAT
48.A
49.B
50.D
51.B
52.A
53.B
54.B
55.C
56.C
57.B
58.C
59.C
60.D
61.E
62.C
63.D
64.A

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