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    BP202TP PDF

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    VINOD CHOUDHARY
    This document outlines a course on Pharmaceutical Organic Chemistry I. [1] It covers topics like classification and nomenclature of organic compounds, structural isomerism, and important reactions and properties of alkanes, alkenes, conjugated dienes, alkyl halides, carbonyl compounds, carboxylic acids, and amines. [2] The objectives are for students to learn structure, naming, reactions and reactivity of these compound classes. [3] Assessment includes qualitative analysis of unknown organic compounds to identify functional groups, derivatives preparation, and molecular modeling.

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    BP202TP PDF

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    137 views2 pages
    This document outlines a course on Pharmaceutical Organic Chemistry I. [1] It covers topics like classification and nomenclature of organic compounds, structural isomerism, and important reactions and properties of alkanes, alkenes, conjugated dienes, alkyl halides, carbonyl compounds, carboxylic acids, and amines. [2] The objectives are for students to learn structure, naming, reactions and reactivity of these compound classes. [3] Assessment includes qualitative analysis of unknown organic compounds to identify functional groups, derivatives preparation, and molecular modeling.

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    This document outlines a course on Pharmaceutical Organic Chemistry I. [1] It covers topics like classification and nomenclature of organic compounds, structural isomerism, and important reactions and properties of alkanes, alkenes, conjugated dienes, alkyl halides, carbonyl compounds, carboxylic acids, and amines. [2] The objectives are for students to learn structure, naming, reactions and reactivity of these compound classes. [3] Assessment includes qualitative analysis of unknown organic compounds to identify functional groups, derivatives preparation, and molecular modeling.

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    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
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    137 views2 pages

    BP202TP PDF

    Uploaded by

    VINOD CHOUDHARY
    This document outlines a course on Pharmaceutical Organic Chemistry I. [1] It covers topics like classification and nomenclature of organic compounds, structural isomerism, and important reactions and properties of alkanes, alkenes, conjugated dienes, alkyl halides, carbonyl compounds, carboxylic acids, and amines. [2] The objectives are for students to learn structure, naming, reactions and reactivity of these compound classes. [3] Assessment includes qualitative analysis of unknown organic compounds to identify functional groups, derivatives preparation, and molecular modeling.

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    © All Rights Reserved
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    of 2

    GUJARAT TECHNOLOGICAL UNIVERSITY

    B.Pharm
    SEMESTER: II
    Subject Name: Pharmaceutical Organic Chemistry I
    Subject Code: BP202TP

    Scope: This subject deals with classification and nomenclature of simple organic compounds,
    structural isomerism, intermediates forming in reactions, important physical properties, reactions and
    methods of preparation of these compounds. The syllabus also emphasizes on mechanisms and
    orientation of reactions.

    Objectives: Upon completion of the course the student shall be able to


    1. write the structure, name and the type of isomerism of the organic compound
    2. write the reaction, name the reaction and orientation of reactions
    3. account for reactivity/stability of compounds
    4. identify/confirm the identification of organic compound

    Course Content:
    General methods of preparation and reactions of compounds superscripted with asterisk (*) to be explained

    To emphasize on definition, types, classification, principles/mechanisms, applications, examples and


    differences

    Sr No Topics %
    weightage
    1. Classification, nomenclature and isomerism: 7
    Classification of Organic Compounds
    Common and IUPAC systems of nomenclature of organic compounds (up to
    10 Carbons open chain and carbocyclic compounds)
    Structural isomerisms in organic compounds
    2. Alkanes*, Alkenes* and Conjugated dienes*: 10
    SP hybridization in alkanes, Halogenation of alkanes, uses of paraffins,
    Stabilities of alkenes, SP hybridization in alkenes, E1 and E2 reactions – kinetics,
    order of reactivity of alkyl halides, rearrangement of carbocations, Saytzeffs
    orientation and evidences. E1 verses E2 reactions, Factors affecting E1 and E2
    reactions. Ozonolysis, electrophilic addition reactions of alkenes,
    Markownikoff’s orientation, free radical addition reactions of alkenes, Anti
    Markownikoff’s orientation.
    Stability of conjugated dienes, Diel-Alder, electrophilic addition, free radical
    addition reactions of conjugated dienes, allylic rearrangement
    3. Alkyl halides*: SN1 and SN2 reactions - kinetics, order of reactivity of alkyl 10
    halides, stereochemistry and rearrangement of carbocations
    SN1 versus SN2 reactions, Factors affecting SN1 and SN2 reactions
    Structure and uses of ethylchloride, Chloroform, trichloroethylene,
    tetrachloroethylene, dichloromethane, tetrachloromethane and iodoform
    Alcohols*- Qualitative tests, Structure and uses of Ethyl alcohol, Methyl
    alcohol, chlorobutanol, Cetosteryl alcohol, Benzyl alcohol, Glycerol, Propylene
    glycol
    4. Carbonyl compounds* (Aldehydes and ketones): Nucleophilic addition, 10
    Electromeric effect, aldol condensation, Crossed Aldol condensation,
    Cannizzaro reaction, Crossed Cannizzaro reaction, Benzoin condensation,
    Perkin condensation, qualitative tests, Structure and uses of Formaldehyde,
    Paraldehyde, Acetone, Chloral hydrate, Hexamine, Benzaldehyde, Vanilin,
    Cinnamaldehyde
    5. Carboxylic acids*: Acidity of carboxylic acids, effect of substituents on acidity, 8
    inductive effect and qualitative tests for carboxylic acids ,amide and ester
    Structure and Uses of Acetic acid, Lactic acid, Tartaric acid, Citric acid,
    Succinic acid. Oxalic acid, Salicylic acid, Benzoic acid, Benzyl benzoate,
    Dimethyl phthalate, Methyl salicylate and Acetyl salicylic acid
    Aliphatic amines* - Basicity, effect of substituent on Basicity. Qualitative test,
    Structure and uses of Ethanolamine, Ethylenediamine, Amphetamine

    Systematic qualitative analysis of unknown organic compounds like:


    1. Preliminary test: Color, odour, aliphatic/aromatic compounds, saturation and
    unsaturation, etc
    2. Detection of elements like Nitrogen, Sulphur and Halogen by Lassaigne’s test
    3. Solubility test
    4. Functional group test like Phenols, Amides/ Urea, Carbohydrates, Amines, Carboxylic
    acids, Aldehydes and Ketones, Alcohols, Esters, Aromatic and Halogenated
    Hydrocarbons, Nitro compounds and Anilides
    5. Melting point/Boiling point of organic compounds
    6. Identification of the unknown compound from the literature using melting point/ boiling
    point
    7. Preparation of the derivatives and confirmation of the unknown compound by melting
    point/ boiling point
    8. Minimum 5 unknown organic compounds to be analysed systematically
    9. Preparation of suitable solid derivatives from organic compounds
    10. Construction of molecular models

    Recommended Books (Latest Editions)

    1. Organic Chemistry by Morrison and Boyd


    2. Organic Chemistry by I.L. Finar , Volume-I
    3. Textbook of Organic Chemistry by B.S. Bahl & Arun Bahl.
    4. Organic Chemistry by P.L.Soni
    5. Practical Organic Chemistry by Mann and Saunders.
    6. Vogel’s text book of Practical Organic Chemistry
    7. Advanced Practical organic chemistry by N.K.Vishnoi.
    8. Introduction to Organic Laboratory techniques by Pavia, Lampman and Kriz.
    9. Reaction and reaction mechanism by Ahluwaliah/Chatwal.

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