Prequalification Exam For Pharmacy 5th Year Students

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Paradise Valley College

December 29, 2020

Pre Qualification Examnation


For Fifth Year Pharmacy Students

1. Mr. Solomon is mostly engaged in administering & enforcing pharmaceutical law, the

Probable area of practice for this pharmacist is

A. Food Medicine and Health Care Administration authority (FMHACA)


B. Pharmaceutical fund and supply agency
C. Industrial pharmacy
D. Ethiopian pharmacist association

2. Mr. Abel, a chronic patient with thrombosis problem in Black lion hospital, is on Warfarin therapy for
a long time. On the other hand he went to a community pharmacy to have medication to get relief from
fever and head ache. A medication that should not be given for Mr. Abel is,
C. Acetyl salicylic acid
A. Acetaminophen
D. Panadol
B. Tramadol
3. Lidiya brings a prescription for her son of 3 years old. A prescription that a pharmacist. should resist
to refill be a prescription containing

A. Chloroamphenicol C. Amoxacilline
B. Cotrimoxazole D. Loratidine

4. Pharmaceutical area in which pharmacists interact daily with healthcare professionals on the patient's
behalf
A. Community pharmacy
B. Industrial pharmacy
C. Pharmacy unit in regulatory authority
D. Pharmacy program training

5. Mr. Emanuel, a pharmacist in outpatient pharmacy in the referral hospital, required to fill a form that
is mandatory before drugs are issued from store to dispensary. The form that should be used is
Paradise Valley College
December 29, 2020

A. Model 19 C. Model 22
B. Model 20 D. Issuing voucher
6. Ms. Bersabel, a clinical pharmacist in Black lion hospital can use one of the following ways to
minimize perceptual differences with her patient during communication
A. Quantifying problems associated with taking drugs
B. Using concepts new to patients
C. Using non specific directions of drug use
D. Using professional terminology
7. A community pharmacist that lead a patient to medication error due to in appropriate advise for
patients related to medication specified
A. Indometacine - before having food
B. Cefalaxine- at regular interval
C. chlorphenramine - Do not drive
D. Bisacodyl enteric coated tablet- Do not chew
8. As a pharmacist which prescription do you accept. A prescription of
A. Propronalol for patient with both congestive heart failure and hypertension
B. Ferrous preparations and dopamine for patient with congestive heart failure
C. Ephedrine for patient with both hypertension and Asthma
D. DENK(German products) when EPHARM products provide comparable efficacy and
safety.
9. A clinical pharmacist working in a hospital with high patient load should give lowest attention for
patient on therapy
A. Cephalaxine C. Phenobarbitone
B. Digoxin D. Metformine
10. Marry brings a prescription with Flumazenil for her son who was on anesthesia for conducting
medical procedures. The probable drug that was used as anesthesia could be
A. Diazepam D. Nitrous oxide
B. Ketamine
C. Propofol
11. Eyoas, a pharmacy coordinator in a community pharmacy, was thinking about ways to reduce
dispensing errors that was mostly observed in his pharmacy. One of the following is not included
under ways to reduce such dispensing errors
A. Pre labeling commonly used drugs
B. Involving more than one individual to process each prescription
Paradise Valley College
December 29, 2020

C. Advising pharmacy professionals to spend short time with patients


D. Improving communication skills of pharmacist

12. Mr. Yonatan, a community pharmacist in Soloda pharmacy, should advise his patient to take in
empty stomach
A. Indomethacin
B. Ketokonazole

C. Niclosamide

D. Omeprazole
13. A medication order, if ordered by the healthcare provider, should the pharmacy professional in
dispensary do not question? Prescription paper with
A. Propronalol for patient with both Asthma and hypertension
B. Ferrous gluconate and ascorbic acid for anemic patient
C. Atropine for patient with tachycardia post to operation
D. Isoniazide and pyridoxine for immunocompromised patients susceptible to TB infection
14. A health care providing facility that a client complain on the service provided. All of the
following may be included under the reaon for such rational drug use except

A.Limited Diagnostic procedures involved in drug prescribing.

B. Supervision programs for prescribers


C. Absence of standard treatment guidelines for the common health problems.
D. Unethical pharmaceutical promotional activities of drug company
15. If anti-acid syrup is administered for patients who is on ferrous gluconate therapy by which way
this OTC medication will be harmful
A. By making ferrous gluconate stronger
B. By making the prescribed drug less effective
C. By masking symptoms of disease
D. By leading to overdose
16. If you were a community pharmacist , a patient that does not need reference
A. Hemophilia
B. A chronic cough that persisted for three weeks
C. Patient with nephrone damage and on Vancomycine therapy
D. Patient with diarrhea due to indigestion
17. Services common to community and hospital Pharmacy
A. Preparing and maintaining a formulary

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December 29, 2020

B. Stocking nursing stations with medications and supplies


C. Participating in drug investigations and research
D. Providing expert consultations on different cases
18. As a manager in hospital pharmacy, you can measure the quality of services focusing on outcome.
Which one of the following parameter does not meet your objective? Measuring the
A. Availability of private counseling area
B. Cost of medication or services
C. Number/percentage of cases reduced due to appropriate medication use
D. Percentage of patient satisfaction
19. A clinical pharmacist should monitor ADR for patient taking
A. INH and Phynitoin
B. Ferrouse with ascorbic acid
C. Insulline in pregnant women
D. Rifampicine for leprosy and TB
20. If a hospital pharmacist wants to conduct drug use evaluation the steps that he should follow
A. Assessing the practice, analysis, Identifying the standard , reporting, recommendation
B. Analysis, identifying the standard , assessing practice, , reporting, recommendation
C. Identifying the standard , assessing the practice, analysis, reporting, recommendation
D. Reporting, Identifying the standard , assessing practice, analysis, , recommendation
21. MR.Abebe is a pharmacist working in the dispensary who always updates his bin card and stock
record card every two weeks diligently. Six weeks ago, he checked that he had 500 tubes of
tetracycline ointment. A week later, he borrowed 250 tubes of tetracycline ointment from the nearby
health center due to measles epidemic eruption and when he updates the bincard next week, he
checked that he had been left with only 150 tubes of tetracycline ointment. The measles epidemic
again occurred in the catchment area of the nearby health center and he lend 50 tubes of tetracycline
ointment in turn to the nearby health center a week later but bought 600 tubes of tetracycline
ointments on the same day he lent to the nearby health center. On the third round bin card update,
what is the total amount of tetracycline available on the shelf?(consider no drug is damaged, expired,
made out of use by any means).
A) 600 B) 700 C) 450. D) 500
22. Ato Tessema is a pharmacist working in Ethiopian food, medicine and health care management
institution and participated on the national drug police draft of Ethiopia which was published recently.
After the long discussion, the committee determined different components of national drug police and
their relation to rational drug use, accessibility of drugs, and quality of drugs to be used in the country.
Accordingly, which of the following national drug police component do you think did the committee
determined to be directly related to rational drug use?

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December 29, 2020

A) Affordability of drugs B) Drug financing C)Regulation and quality assurance of the


drugs D) Supply system
23. Mr Fitsum, Abebe and Galatea are pharmacists working in the distribution of program drugs which
are mainly donated by UNICEF and they give on job training to other staffs working with them with
regard to port clearing, receipt and inspection, inventory control and storage of pharmaceuticals.
During their training, they give due attention to the sequence of events of the above mentioned
activities. Which of the following is the correct order of these activities do you think iscorrect?
A) Receipt and inspection>inventory control> port clearing>storage>
B) Port clearing> storage> inventory control> receipt and inspection
C) Port clearing> receipt and inspection> inventory control >storage
D) Storage> inventory control> receipt and inspection> port clearing
24. Mr X, Y, &Z are pharmacists working together in the same hospital and had discussion about drug
procurement procedure they should follow for the recently invented drug and had been given to a
particular drug manufacturing company as a patent right( to be manufactured in brand name of the
company). Suppose it is a must for the hospital to procure the drug, which method of drug
procurement they should follow?

A) Competitive Negotiation B) Direct Procurement C) Restricted Tender D) Open Tender

25. Shashemane health center has a regular drug disposal program for damaged, expired and for all drugs
made out of use. According to drug disposal guide line, it is a must that manufacturing date,
manufacturing industry and country, expire date, price, batch number, dosage form, etc are
documented and all disposal committee should sign on each pages of the document. According to the
Ethiopian drug disposal guideline, who are the members of drug disposal committee?

A) Head of health institution, pharmacist, finance manager, laboratory depth. Head, police,

Judiciary head of municipality & matron

B) All management members of the health institution

C) All board members of the health institution

D) Pharmacist, matron, head of institution, head of laboratory depth. And finance managers

Only

Case I: If the number of patients treated annually for uncomplicated UTI in Halaba primary hospitals is
2200, from which 1200 were women and others are men. All causes were treated with cotrimoxazole oral
preparations.

 (Dose for adult women = Sulfamethoxazole+trimethoprim, 800mg/160 mg P.O. BID, for 5 days.

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 Dose for adult men = Sulfamethoxazole+trimethoprim, 800 mg/160 mg P.O. BID, for 10days

26. Quantity of 480 mg cotrimoxazole tablet specified for a standard course of treatment for a single
women and men respectively

A. 5, 10 C. 15,30

B. 20,40 D. 40,20

27. Total quantity of 480mg cotrimoxazole tablet in packs required for all patients in the health facility
ifonepackcontains10stripsof20tabs

A. 120

B. 160

C. 200

D. 320

28. If the cost/pack is 200 Ethiopian birr, the total cost of cotrimoxazol for both women and men in will
be

A. 24000 C. 40000

B. 32000 D. 64000

29. In the previous purchases competitive negotiation method was used and the cost of cotrimoxazole for
the same quantity was 3 times more cost comparing with the current purchase. The probable
procurement method that is used in current purchase is

A. Restricted tender

B. Competitive negotiation

C. Direct procurement

D. Sole source purchase

Case II: Assume that a procurement period in Adare general hospital is quarterly, average Lead time from
the previous purchases were two weeks, average monthly consumption of Cephalexin 500 mg capsule is
2000 packs, safety stock level of one month, Stock on hand is 500 packs and Stock on order but not
received yet is 1000 packs. Then

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30. The minimum stock level of Cephalexin

A. One months C. Two months

B. One and half months D. Two and half months

31.The maximum stock level of Cephalexin in Adare Hospital

A. Three months C. Four months

B. Three and half months D. Four and half months

32. Determine Cephalexin quantity to be ordered in terms of packs

A. 6000 C. 7500

B. 8500 D. 9000

33. Mr. Emanuel, a logistic coordinator in pharmacy unit of Adare hospital, should follow one of the
following steps to procure items

A. Identify what to procure, Determine how much to procure, Reconcile Need with Budget,
Determine when to buy, select suppliers, Prepare purchase order

B. Reconcile need with Budget, Determine when to buy, ,select suppliers, Prepare purchase
order, Identify what to procure, Determine how much to procured

C. Determine how much to procured, Identify what to procure, Reconcile Need with Budget,
Determine when to buy, select suppliers, Prepare purchase order

D. Select suppliers, Prepare purchase order, Identify what to procure, Determine how Un
advisable practice while maintain cold storage

34. Mr. Gemechis, a store man in Batu hospital fails to keep good storage practice for pharmaceutical
products. The probable arrangement for such judgment could be

A. heavy items on upper shelves

B. fragile items on the lower shelves

C. Frequently picked items on the middle part of shelves

D. Extra stock on the upper shelves

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35. Storing in a dry, clean and well-ventilated area, in a temperature between 150-250C or up to 300C is
related to a label on pack stating

A. Store frozen C. Store at room temperature

B. Keep cool D. Store at ambient temperature

case III: Based on the following bin-card that was used in Durame hospital in the last year,
answer question number 17-19

BIN CARD
Name of the health facility: Durame Hospital
Name, strength and dosage form of the pharmaceutical: ciprofloxacin 500 mg tab. Unit of
issue: Packs (10x10 tabs)

Date (E.C) Doc. No Received Quantity Batch Expiry date Remarks


(Receiving from or No.
or issued to Receive Issued Loss/ Balance
Issuing) d adj.

05/01/10 300 03258 06/2025 Transfer from last


year
01/02/10 Physical 280 03258 06/2025
inventory
18/02/10 00068 Dispensary 180 03258 06/2025
02/03/10 00080 Dispensary 20 03258 06/2025

02/03/10 00081 Inpatient 25 03258 06/2025


pharmacy
10/04/10 5 06/2025 With capping
problem
15/04/10 00098 Dispensary 50 03258 06/2025 Stock out

30/04/10 14236 PFSA 250 04562 03/2028


25/04/10 14236 Dispensary 150 04562 03/2028
30/04/10 14236 Dispensary 100 04562 03/2028

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36. Total consumption of ciprofloxacin for all given review periods


A. 525
B. 520
C. 530
D. 550
37. The average monthly consumption
A. 175
B. 184
C. 210
D. 220
38. What will be the amount of ciprofloxacin that should be order assuming that the maximum
stock level is 4 months, the minimum stock level is 2 months, quantity ordered but not
received yet is 340 packs

A. 840
B. 340
C. 640
D. 500

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39. A medication that does not need special storage condition

A) Codeine tablet

B) Adrenalin

C) Alcohol

D) Ergometerine maleate injection

40. Mr. Ayele, a hypertensive patient in Adare hospital, wants to get an affordable drug. Which one of
the following is not included under the means that increase drug affordability to this patient?

A) Getting better drug information

B) Receiving brand products

C) Being paid by insurance companies

D) Getting generic name products

41. Ayisha, a pharmacy coordinator in the logistic management unit of referral hospital, thought to use
morbidity method for quantifying drugs as a must. The probable reason could be

A) Availability of complete and reliable consumption data

B) Rational prescribing trend in the hospital

C) Un interrupted drug supply system in the hospital

D) A high level of avoidable wastage with in the hospital

Ms. Hana, a pharmacist working in outpatient pharmacy unit of Hayider Hospital, wants to request
Doxycycline 100 mg capsule from the store. Before 2 weeks (1/6/2012 E.C.)There was 200packs of
Doxycycline in her bin that was confirmed by physical inventory. After 1 week on (8/6/2012 E.C.)She
received 100 packs from the store. Now (15/6/2012 E.C.) she has left with 25 packs. Based on the given
case answer the following two questions

42. The minimum amount that should be requested for the next two weeks from the store should be
A. 300 packs
B. 275 packs
C. 200 packs
D. 100 packs

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43. The amount of Doxycycline that was dispensed with in two weeks was
A. 300 packs
B. 275 packs
C. 25 packs
D. 100 packs
44. A 60-year-old-man has a 5-month history of progressive weakness and a weight loss of 13 kg along
with intermittent fever, chills, and a chronic cough productive of yellow sputum, occasionally
streaked with blood. A sputum specimen is obtained, and numerous acid-fast bacteria are seen on the
smear. Culture of the sputum is positive for Mycobacterium tuberculosis. Which treatment regimen
is most appropriate for initial therapy?
A. Isoniazid and rifampin
B. Sulfamethoxazole- trimethoprim and streptomycin
C. Isoniazid, rifampin, yrazinamide and ethambutol
D. Isoniazid, cycloserine and ciprofloxacin
45. A 41-year-old female is seen in the psychiatric clinic for a follow-up appointment. She has been
taking an antidepressant for three weeks with some improvement in mood. However, she complains
of drowsiness, palpitations, dry mouth, and feeling faint on standing. Which antidepressant is she
taking?
A. Amitriptyline
B. Trazodone
C. Fluoxetine
D. Venlafaxine
46. Your 23-year-old female patient is pregnant and has gonorrhea. The past medical history includes
anaphylaxis following exposure to amoxicillin. Worried about compliance, you would like to treat
this patient with a single dose, so you chose
A. Cefixime
B. Ceftriaxone
C. Ciprofloxacine
D. Spectinomycin
47. A 19-year-old woman with recurrent sinusitis has been treated with different antibiotics on several
occasions. During the course of one such treatment she developed a severe diarrhea and was
hospitalized. Sigmoidoscopy revealed colitis, and pseudomembranous, were confirmed
histologically. Which of the following drugs, administered orally, is most likely to be effective in the
treatment of colitis due to C difficile?

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A. Ampicillin
B. Cefazolin
C. Clindamycin
D. Metronidazole
48. A 45 years old man with history of alcoholic cirrhosis is seen in the clinic today for follow up. He
was recently referred for screening endoscopy, which showed several large esophageal varices. He
has no history of bleeding; 1 month ago, he was placed on propranolol 10mg orally 2 times /day. At
that time, his vital sign included temperature 98.7°F, HR 85 beats/minute, RR 15, and BP
130/80mmHg. At his evaluation today, he seems to be tolerating his propranolol and has no new
complaints. His vital sign now include temperature 98.6°F, HR 83 beats/minute, RR 14, and BP 128/
78mmHg F=(C*180/100) +32 (36.4-37.2) . Which one of the following is the best course of action at
this time?
A. Continue current therapy with close follow up in 4 week
B. Increase propranol to 20mg orally 3 times/day
C. Add isosorbidedinitrate 10mg orally 3 times/day
D. Change propranol to ayenolol 25mg orally once daily
49. N.M is 36 year old male patient present to the hospital which you are working with chief compliance
of chronic cough, lack of appetite, head ache, fever and vomiting. Physical examination reveals
abnormal increase heart rate HR=120beats/minute, abnormal respiratory rate RR=30 beats/minutes
and hypotension BP=90/60. One of the following indicate demographic information for N.M
A. Lack of appetite
B. Chronic cough
C. Age of the patient
D. Increased heart rate
50. N.T is 36 year old male patient come to nearby hospital with chief compliance of cough, shortness of
breathing, head ache, fever and lack of appetite. In the hospital physical examination done indicates
Temperature= 40oc, BP= 130/85, HR= 100beats/minute and RR=30breaths/minutes. Which of the
following is objective data from the case given above
A. Shortness of breathing
B. BP
C. Cough
D. Lack of appetite
51. L.D is 37 years old female patient with pneumonia confirmed with clinical sign and symptom and
chest X-ray. Her medication history reveals that she has no other chronic and acute medical

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condition and currently she has no medication taking in her home. In addition, L.D not drinks
alcohol, coffee and not smokes cigarettes. Based the above case given the treatment goal for L.D is--

A. Reduce or eliminate symptom of the disease


B. Prevent or to halt disease progression
C. To cure the disease
D. To prevent the disease
52. Y.N is 45 years old female patient with type 2 diabetic mellitus confirmed with clinical sign and
symptom and blood glucose test. Her medication history reveals that she has no other chronic and
acute medical condition and currently she has no medication in her home. In addition, Y.N not
drinks alcohol, coffee and not smokes cigarettes. Based the above case given the treatment goal for
Y.N is -----
A. To normalize laboratory abnormality
B. To prevent or halt disease progression
C. To cure the disease
D. To prevent disease
53. Suppose new patient with rheumatoid arthritis present prescription indomethacin 50mg TID, you
instruct your patient to take the medication with food. What is your most likely objective such
instructions
A. To prevent future development of DTP
B. To achieve goal of therapy
C. To resolve drug therapy problem
D. To cure the disease

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54. Y.Y is 37 years old female patient with chronic heart failure confirmed with clinical sign and
symptom like fatigue, productive cough peripheral edema and abnormal heart murmur. Y.Y ECG
result revealed abnormal left ventricle enlargement and percent of ejection fraction of 35% and Y.Y
serum laboratory result indicate Na=100MEQ/L (normal rage=135-145MEQ/L), Ca=9.5mg/dl
(normal rage 8.5=10.5mg/dl) and Ka= 4MEQ/L (normal rage= 3.5-5.5MEQ/L). which of the
following is the most likely cause of hyponatremia of Y.Y based on the information given on the
case
A. Impaired GFR
B. Thiazide diuretics
C. Chronic heart failure
D. Productive cough
55. O.O is 25 years old female known type 1 diabetic mellitus patient taking insulin for the last three
years but in last two weeks she did not take insulin dose. O.O come the nearby hospital with acute
complication of diabetic ketoacidosis and the laboratory tests indicated that NaHCO3=12MEQ/L,
RBS=300mg/dl, serum PH=5.6 (normal rage PH=7.35-7.45), anion gap=20MEQ/ML (normal range
of=5-12MEQ/ml) and serum chlorine=120MEQ/L (normal rage 95-105MEQ/L). Which of the
following is the most likely cause of Hyperchloremia of O.O based on the information given on the
case
A. Metabolic alkalosis secondary to vomiting
B. Vomiting secondary to diabetic ketoacidosis
C. Metabolic acidosis secondary to diabetic ketoacidosis
D. Excessive sodium and water retention
56. N.N is 50 years old male patient presented nearby hospital with mild pain secondary hand trauma
due to car accident. N.N medical history revealed that he had diagnosed PUD secondary to H.pylori
taking triple treatment since two days ago. Which of the following is drug of choice initial treatment
of pain for N.N
A. Incomethacin
B. Acetaminophen
C. Ketoprofen
D. Piroxicam

57. H.H is 37 years old man is seen in the clinic for complaints of sharp epigastric pain for the past 6
weeks. He states that the pain is often worse with eating and that it is present at least 5 days/week.
He states that although he initially tried OTC antacids with some relief, the pain returns about 3

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hours after a dose. He does not take any other medications. H.H medication history reveals he is not
taking any medication currently and not have allergy for any medication. H.H endoscopic result
shows PUD and the H.pylori test with Rapid Urease test, the result of which is positive. The
attending physician and clinical pharmacist decided to initiate triple treatment then which of the
following treatments for H.pylori would be best at this time for H.H based the information given
above
A. Amoxicillin 1gram 2 times /day plus clarithromycin 500mg 2 times/day plus
omeprazole 20mg 2 times/day for 10 days
B. Cephalexin 1gm 2 times/day plus clarithromycin 500mg 2 times/day plus omeprazole
20mg 2 times/day for 10 days
C. Bismuth subsalicylate 525mg 4 times/day plus tetracycline 500mg 4 times/day plus
metronidazole 500mg 3 times/day plus omeprazole 20mg 2 times/day for 14 days
D. Levofloxacin 500mg once daily plus metronidazole 500mg 2 times/day plus
omeprazole 20mg 2 times/day for 5 days
58. K.K is 57 years old female patient presented with heart burn, water brash, Belching, regurgitation,
chronic cough, hoarseness, Dysphagia, odynophagia and choking. The patient states that the typical
symptoms are aggravated in recumbent position, bending over and eating fat meal. K.K is known
arrhythmic patient taking anti-arrhythmic treatment for the last two years. K.K endoscopic result
shows GERD with esophagitis and attending physician and clinical pharmacist decided to initiate
treatment for K.K. which of the followingtreatment is contraindicated for K.K based on the
information given on the case
A. Omeprazole
B. Cimetidine
C. Cisapride
D. Metoclopramide
59. A 42 years old man is seen in the clinic for complaints of sharp epigastric pain for the past 6 weeks.
He states that the pain is often worse with eating and that it is present at least 5 days/week. He states
that although he initially tried OTC antacids with some relief, the pain returns about 3 hours after a
dose. He does not take any other medications. He reports an allergy to penicillin, which, he states,
gives him a severe rash. His practitioner is concerned about a potential peptic ulcer and tests him for
H.Pylori using urea breath test, the result of which is positive. Which of the following treatments for
H.Pylori would be best at this time?
A. Amoxicillin 1gram 2 times /day plus clarithromycin 500mg 2 times/day plus omeprazole
20mg 2 times/day for 10 days

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B. Cephalexin 1gm 2 times/day plus clarithromycin 500mg 2 times/day plus omeprazole


20mg 2 times/day for 10 days
C. Bismuth subsalicylate 525mg 4 times/day plus tetracycline 500mg 4 times/day plus
metronidazole 500mg 3 times/day plus omeprazole 20mg 2 times/day for 14 days
D. Levofloxacin 500mg once daily plus metronidazole 500mg 2 times/day plus omeprazole
20mg 2 times/day for 5 days
60. A patient with PUD was prescribed with drugs having the highest gastric acid suppression potency.
Which classes of the drugs do you think to be this category?
A. H2-Receptors antagonists
B. Proton pump inhibitors
C. Cyto-protective agents
D. Prostaglandin agonists
61. FN is 63 year old female patient's blood pressure within a desired range of 110–120/70–80 within 2
months the practitioner initiates pharmacotherapy with 50mg of hydrochlorothiazide every morning,
a sodium restricted diet, and a low impact exercise program. At the 60-day follow-up evaluation, the
patient's blood pressure was 112/80 and her hypertension. Clinical outcome of status of this patient
is described as
A. Partially improved
B. Unimproved
C. Stable
D. Worsened
62. T is 37 years old male patient with koilonychias, glossitis, angular stomatitis, difficulty of
swallowing and other symptoms like: fatigue, lethargy, Shortness of breath headache, dizziness and
pallor. He has history of melena due to PUD two weeks ago. His current CBC results are: RBC= 3.4
million per cubic centimeters, Hb= 10g/dl, HCT= 31%, MCHC= 27g/dl and MCV= 60fL. Which
type of anemia L.T has
A. Normocytic and normochromic anemia
B. Microcytic and normochromic anemia
C. Microcytic and hypochromic anemia
D. Macrocytic and hypochromic anemia
63. G.L is 27 years male patient with acute uncomplicated appendicitis taking ceftriaxone 2g IV BID
and metronidazole 500mg IV TID. He has no known drug allergy and his medical condition is
improved after taking both medications for 72 hours. Currently he is afebrile and WBC is in normal
rage and then attending physicians asked you the dose regimen of metronidazole for PO conversion

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to finish the remaining 7 days of treatment. Which the following dose regimen should be
recommended?
A. Metronidazole 500mg PO TID for 07 days
B. Metronidazole 500mg PO BID for 10 days
C. Metronidazole 750mg PO TID for 07 days
D. Metronidazole 750mg PO BID for 07 days
64. M.L is 65 years male patient with heart failure and known grade three edema taking 40mg of
furosemide IV QD. After three days of treatment, his edema subsides significantly and the attending
physician wants to change furosemide from IV to PO. Which of the following dose regimen is best
recommendation for frusemide?
A. Furosemide 40mg PO QD
B. Furosemide 80mg PO QD
C. Furosemide 80mg PO BID
D. Furosemide 40mg PO BID
65. After undergoing surgical resection for carcinoma of the stomach, a 60-year-old male has developed
numbness in his feet. On exam he has lost proprioception in the lower extremities and has a wide-
based gait and positive Romberg. A peripheral blood smear shows macrocytosis and
hypersegmentedpolymorph nuclear leukocytes. The neurologic dysfunction is secondary to
A. Folic acid
B. Thiamine
C. Vitamin B12
D. Iron
66. TH is 45 years old female patients with sign and symptom of anemia and neurological symptom. TH
laboratory finding reveals that decreased level of hemoglobin, RBC, HCT and increased level of
MCV then one of the following laboratory findings is specific to vitamin B12 deficiency
A. Elevated level of MCV
B. Elevated level of homocysteine
C. Elevated level of methylmalonic acid
D. Decreased level of MCV
67. G.N is 37 years male patient drinking alcohol starting from 15 years old and hence develops alcohol
dependence. Initially he was drinking 5 bottles of standard beer per day and then now he is drinking
more than 20 bottles of standard beer per day. Which of the following drugs can be used to treat G.N
alcohol dependence
A. Disulfiram

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B. Naltrexone
C. Morphine
D. “A” & “B”
68. In question 24 G.N has persistent desire control alcohol use, to do so he stopped drinking alcohol for
the last five consecutive days at which time he came to emergency department of your hospital with
confusion, Disorientation, hypertension, tachycardia, fever auditory hallucinations and Hyper
responsiveness. Which of the following is most likely diagnosis for G.N?
A. Alcohol intoxication
B. Alcohol dependence
C. Delirium tremens
D. Alcohol withdrawal
69. Which of the following is best drug of choice for management of G.N in the above question 24
A. Benzodiazepine
B. Carbamazepine
C. Haloperidol
D. CPZ
70. R.T is 60 years old male patient with mild pain due to trauma come to the nearby hospital. In the
hospital appropriate history, physical examination and laboratory diagnosis were done. His
laboratory results were: liver faction test with Alanine Aminotransferase (ALT)= 180IU/L (normal
rage=0-35 IU/L), Asparate Aminotransferase (AST)= 115 IU/L ( normal rage= 0-35IU/L) and
kidney function test with serum creatinine= 0.9mg/dl (normal rage= 0.6-1.2mg/dl) and
GFR=110ml/minute (normal rage= 90-130ml/minute) then based on the above information which of
the following anti-pain drug/s is/are contraindicated for management of pain for R.T
A. Ibuprofen
B. Diclofenac sodium
C. Acetaminophen
D. Indomethacin
71. A 25-year-old male is seen in the emergency department (ED). He is disoriented but states that he
has had nausea, vomiting, abdominal pain, and diarrhea since he took “too many pain pills.” Before
he can tell you more, he loses consciousness. Liver function tests are abnormal. In addition to gastric
lavage, what is the appropriate treatment?
A. Naloxone
B. Diphenoxylate
C. N-acetyl-L-cysteine

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D. Pralidoxime
72. A 33-year-old female patient treated with haloperidol for a history of schizophrenia is seen in the ED
because of complaints of fever, stiffness, and tremor. Her temperature is 104°F, and her serum
creatine kinase (CK) level is elevated. What has occurred?
A. Overdose
B. Neuroleptic malignant syndrome
C. Tardive Dyskinesia
D. Parkinsonism
73. A pediatric patient is visited your health institution and diagnosed for absence seizure. Which of the
following antiepileptic agent is preferable for this type seizure?
A. Carbamezine
B. Valproic acid
C. Phenytoin
D. Phenobarbital
74. Although a patient was instructed not to use alcohol because of a medication he was taking, he did
not listen to advice and decided to have a drink of alcohol. Within minutes, he developed flushing, a
throbbing headache, nausea and vomiting. Which of the following medications was he taking?
A. Naltrexone
B. Diazepam
C. Disulfiram
D. Phenobarbital
75. A 58-year-old man is admitted to the hospital with acute heart failure and pulmonary edema. Which
one of the following drugs would be most useful in treating the pulmonary edema?
A. Digoxin.
B. Dobutamine.
C. Furosemide.
D. Minoxi

76. A 66-year-old man had a myocardial infarct. Which one of the following would be appropriate
prophylactic antiarrhythmic therapy?
A. Lidocaine
B. Metoprolol
C. Procainamide

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D. Quinidine
77. A 68-year-old man has been successfully treated for exercise-induced angina for several years. He
recently has been complaining about being awakened at night with chest pain. Which of the
following drugs would be useful in preventing this patient's nocturnal angina?
A. Amylnitrite
B. Nitroglycerine (subligual)
C. Nitroglycerin (transdermal
D. Esmolol
78. A 58-year-old woman is being treated for chronic suppression of a ventricular arrhythmia. After 2
months of therapy, she complains about feeling tired all the time. Examination reveals a resting heart
rate of 10 beats per minute lower than her previous rate. Her skin is cool and clammy. Laboratory
test results indicate low thyroxin and elevated thyroid-stimulating hormone levels. Which of the
following antiarrhythmic drugs is the likely cause of these signs and symptoms?

A. Amiodarone.

B. Procainamide.

C. Propranolol.

D. Quinidine

79. A 45-year-old man has recently been diagnosed with hypertension and started on monotherapy
designed to reduce peripheral resistance and prevent NaCl and water retention. He has developed a
persistent cough. Which of the following drugs would have the same benefits but would not cause
cough?

A. Losartan.

B. Nifedipine.

C. Prazosin

D. Propranolol

80. An elderly patient with a history of heart disease and who is having difficulty breathing isbrought
into the emergency room. Examination reveals that she has pulmonary edema. Which of the
following treatments is indicated?

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A. Spironolactone. C. Acetazolamide.

B. Furosemide. D. Chlorthalidone

81. A 55-year-old male with kidney stones has been placed on a diuretic to decrease calcium excretion.
However, after a few weeks, he develops an attack of gout. Which diuretic was he taking?

A. Furosemide. D. Triamterene

B. Hydrochlorothiazide. .

C. Spironolactone.

82. A 75-year-old woman with hypertension is being treated with a thiazide. Her blood pressure
responds and reads at 120/76 mm Hg. After several months on the medication, she complains of
being tired and weak. An analysis of the blood indicates low values for which of the following ?

A. Calcium. C. Potassium.

B. Uric acid. D. Sodium

83. Which would be the initial treatment choice to manage the hypertension in an African-American
woman with a past medical history of gout and severe hypokalemia?

A. Hydrochlorothiazide

B. Spironolactone

C. valsartan

D. Atenolol

84. .A 50-year-old woman has just been diagnosed as a Type 2 diabetic and given a prescription for
metformin. Which of the following statements is characteristic of this medication?

A. Hypoglycemia is a common adverse effect. C. Many drug-drug interactions have been


identified.
B. Metformin undergoes metabolism to an active
compound. D. It decreases hepatic glucose production

85. A 59-year-old female with mild CHF is treated with furosemide. What is its primary mechanism of
action?

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a. Inhibition of sodium-potassium (Na+,K+) adenosine triphosphatase (ATPase)


b. Inhibition of Na+,K+, chloride (Cl-) co-transporter
c. Inhibition of Na+,Cl- co-transporter
d. Inhibition of Cl- transporter
e. Inhibition of Ca2+ divalent cation (Ca2+) transporter
86. A 70-year-old female is treated with sublingual nitroglycerin for heroccasional bouts of angina.
Which of the following is involved in the actionof nitroglycerin?
a. α-adrenergic activity
b. Phosphodiesterase activity
c. Phosphorylation of light chains of myosin
d. Norepinephrine release
e. Cyclic guanine monophosphate (cGMP)
87. A 45-year-old male post–myocardial infarction (post-MI) for one week is being treated with
intravenous (IV) heparin. Stool guaiac on admission was negative, but is now 4+, and he has had an
episode of hematemesis. The heparin is discontinued, and a drug is given to counteract the bleeding.
What drug was given?
A. Aminocaproic acid
B. Dipyridamole
C. Factor IX
D. Protamine
88. A young boy is diagnosed with asthma. His primary symptom is frequent cough, not bronchospasm
or wheezing. Other asthma medications are started, but until their effects develop fully we wish to
suppress the cough without running a risk of suppressing ventilatory drive or causing sedation or
other unwanted effects. Which of the following would best meet these needs?
A. Codeine
B. Dextromethorphan
C. Diphenhydramine
D. Hydrocodone
89. A 24-year-old man is taking two medications to help with the symptoms of allergic rhinitis. He is
noted to have a blood pressure of 150/70 mmHg. The clinician notes that one of the medications may
be responsible for the new-onset hypertension. The most likely etiology is:
A. Inhaled cromolyn
B. Inhaled glucocorticoids
C. Oral diphenhydramine

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D. Oral pseudoephedrine
90. A 48-year-old man comes to your office with a 2-day history of fever and abdominal pain. He
complains of pain in joint area and diarrhea.He has no other significant medical history. On
examination, his temperature is 39.5°C (103.1°F), his respiratory rate is 24 breaths per minute; pulse,
75 beats per minute; and blood pressure, 120/75 mmHg. The blood culture results confirm the
diagnosis of typhoid fever caused by Salmonella typhi. What is a drug of choice to treat thispatient?
a. Ciprofloxacin 500mg tab BID for 7 days
b. Amoxicillin 500mg caps TID for 7 days
c. Tetracycline 250mg caps QID for 7 days
d. Erythromycin 500mg tab QID for 7 days
91. You are taking an initial health history from a 22-year-old womanwho just moved to your town. She
is remarkably fit and healthy, but is wearing two hearing aids for binaural (bilateral) high-frequency
hearing loss. You inquire about the possible reason(s) for this. She says she lost most of her hearing
after receiving an antibiotic for a severe infection when she was 19, but cannot recall the specific
drug. Which of the following drugs was most likely responsible for her hearing loss?
A. Aminoglycoside (e.g., gentamicin)
B. Cephalosporin, first-generation
C. Cephalosporin, third-generation
D. Fluoroquinolone (e.g., ciprofloxacin)
92. A woman wants a prescription for an oral contraceptive, and your choice is between an estrogen-
progestin combination and a “minipill” (progestin only). A main difference is that, compared with
the hormone combination products, progestin-only drugs:
A. Are associated with a higher risk of thromboembolism
B. Cause more menstrual irregularities (irregular cycle length, amenorrhea, spotting)
C. Have better contraceptive efficacy
D. Must be taken on an irregular cycle, rather than daily, so compliance is hindered
93. A patient with an opportunistic infection with Pneumocystis carinii is receiving a combination of
sulfamethoxazole(SMZ) and trimethoprim (TMP). Which of the following statements describes best
the mechanism by which this combination exerts its desired effects—and does so better than if just
one of the drugs was administered?
A. The combination exerts significant antiviral activity, thereby reducing the risk of
opportunistic P. carinii infections during antiviral therapy with other medications
B. The SMZ permeabilizes bacterial cell walls, allowing better penetration ofthe TMP

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C. They inhibit sequential steps in bacterial synthesis of tetrahydrofolic acid


D. TMP inhibits production of resistance factors (“R-factors”) directed against SMZ
94. A 39-year-old woman with a history of recurrent urinary tract infections develops a new infection.
Culture of a urine sample indicated that the offending organism is Escherichia coli. She receives
therapeutic doses of ciprofloxacin. Symptoms disappear as the offending bacteria are destroyed.
Which of the following is the main bacterial process or enzyme that was inhibited by ciprofloxacin?
A. Cell-wall synthesis
B. Protein synthesis
C. Folic acid synthesis
D. Topoisomerase II (DNA gyrase)
95. Blood and sputum cultures taken in a critically ill 26-year-old woman indicate the presence of
MRSA—methicillin-resistant Staphylococcus aureus. Which of the following drugs is most likely to
be effective in treating this infection?
A. Amoxicillin plus clavulanic acid
B. Clindamycin
C. Trimethoprim-sulfamethoxazole (TMP-SMZ)
D. Vancomycin
96. A 25-year-old male is seen in the emergency department (ED). He is disoriented but states that he
has had nausea, vomiting, abdominal pain, and diarrhea since he took “too many pain pills.” Before
he can tell you more, he loses consciousness. Liver function tests are abnormal. In addition to gastric
lavage, what is the appropriate treatment?
A. Naloxone
B. Diphenoxylate
C. N-acetyl-L-cysteine
D. Pralidoxime
97. A 3-year-old female ingests a bottle of aspirin by accident. Amongthe therapeutic interventions,
which of the following should be included?
a. Dimercaprol c. Penicillamine
b. Deferoxamine d. Activated charcoal
98. A 50-year-old male chronic alcoholic ingests methanol. Which of thefollowing findings is associated
with acute methanol ingestion?
a. Metabolic alkalosis c. Blurred vision
b. Delirium tremens d. Tachypnia

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99. A 60-year-old male complains of severe headaches, nausea, dizziness, and a diminution in vision. He
has a decrease in oxygen (O2)-carrying capacity without a change in the PO2 of arterial blood.
Which of the following might account for these findings?
a. Sulfur dioxide c. Nitrogen dioxide
b. Ozone d. Carbon monoxide (CO)
100. A 2-year-old male ingests iron pills by accident. He develops severeabdominal pain and bloody
vomitus. Which of the following might beadministered to this patient?
a. Dimercaprol c. Penicillamine
b. Deferoxamine d. Activated charcoal
101. A 23-year-old visited your health institution with a syndrome of flushing,headache, nausea,
vomiting, sweating, hypotension, and confusion after excess ethanol consumption. Which drug is
preferable to reverse the complications?
a. Fomepizole IV c. Atropine sulphate IV
b. Calcium gluconate IV d. Methanol IV

102. An elderly man with COPD is being managed with several drugs, one of which is inhaled
ipratropium. Which of the following is the main mechanism that accounts for the beneficial effects
of this drug?
A. Blocks of an endogenous bronchoconstrictor mediator
B. Enhances release of epinephrine from the adrenal medulla
C. Inhibits cAMP breakdown via phosphodiesterase inhibition
D. Prevents antigen-antibody reactions that lead to mast cell mediator release
103. A 27-year-old female has just returned from a trip to Southeast Asia. In the past 24 hours, she has
developed shaking, chills, and a temperature of 104°F. A blood smear reveals Plasmodium vivax.
Which of the following agents should be used to eradicate the extraerythrocytic phase of the
organism?
A. Primaquine
B. Pyrimethamine
C. Quinidine
D. Chloroquine
104. A 40-year-old female with a history of AIDS develops a zoster infection. Which of the following
antiviral agents should be administered for this case?
A. Ganciclovir 1g TID for 21days
B. Acyclovir 800mg 5 times daily for 7-10days

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C. Zidovudine 300mg BID for 14 days


D. Penciclovir 1% every 2h while awake
105. A patient with asthma has moderate bronchospasm and wheezing about twice a week. Current
medications are inhaled albuterol, used for both prophylaxis and to abort ongoing attacks (rescue
therapy), and inhaled beclomethasone. If the physician chooses to use salmeterol, which of the
following states best the way it should be used in this patient’s management?
A. A replacement for the albuterol
B. A replacement for the corticosteroid
C. Primary (sole) therapy, replacing both albuterol and the steroid
D. The preferred agent for acute symptom control (rescue therapy)
106. A 63-year-old man suffering from a small cell carcinoma of the lung was hospitalized for his first
cycle of chemotherapy. Which of the following three-drug regimens would be the best to prevent
nausea and vomiting in this patient?
A. Ranitidine, diazepam, dexamethasone
B. Scopolamine, dexamethasone, ondansetron
C. Ondansetron, aprepitant, dexamethasone
D. Aprepitant , scopolamine, loperamide
107. A patient being cared for by the gastroenterology service is being treated with sulfasalazine.
Which of the following is the most likely purpose for which it is being given?
A. Antibiotic-associated pseudomembranous colitis
B. E. coli–induced diarrhea
C. Gastric H. pylori infections
D. Inflammatory bowel disease
108. A 45-year-old man has recently been diagnosed with hypertension and started on monotherapy
designed to reduce peripheral resistance and prevent NaCl and water retention. He has developed a
persistent cough. Which of the following drugs would have the same benefits but would not cause
cough?
A. Losartan.
B. Nifedipine.
C. Prazosin
D. Propranolol

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109. An elderly patient with a history of heart disease and who is having difficulty breathing isbrought
into the emergency room. Examination reveals that she has pulmonary edema. Which of the
following treatments is indicated?
A. Spironolactone.
B. Furosemide.
C. Acetazolamide.
D. Chlorthalidone
110. A 50-year-old woman has just been diagnosed as a Type 2 diabetic and given a prescription for
metformin. Which of the following statements is characteristic of this medication?
A. Hypoglycemia is a common adverse effect.
B. Metformin undergoes metabolism to an active compound.
C. Many drug-drug interactions have been identified.
D. It decreases hepatic glucose production
111. A researcher was interested to test a certain hypothesis at 95% confidence interval. After performing
all the required steps, he found a P-value of 0.05. What should be his conclusion based on this
information?
A. Reject the null hypothesis
B. Accept the alternative hypothesis
C. The difference between the sample value and the population is merely by chance
D. None of the above
112. Assume that the following data represent age of 10 mothers who gave birth at Hawassa Referral
Hospital on a particular day: : 22, 20, 21, 45, 24, 21, 25, 22, 26 and 24. Which measure of central
tendencies will you recommend to summarize age of these mothers?
a. Arithmetic mean
b. Median
c. Modal
d. All of the above
113.A Biostatistics instructor in your college wanted to calculate the second quartile of the above 10
mothers, what would be it? A.7 B. 12 C. 16 D. 19

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114.A nurse working in Labor Ward of a particular health center assessed degree of pain that
laboring mothers experience using a five scale items (tolerable, intense, very intense, horrible &
unimaginable). Which scale of measurement was used by the nurse?

a. Nominal B. Ratio C. Ordinal D. Interval scale


115. The HIV positive rate in a randomly selected sample of 200 people is 11.0%. Which ONE of the
following is the correct 95% confidence interval for the population parameter (normal approximation
method)? A. 8.83% to 13.17% B. 8.83% to 15.34%
C. 6.66% to 13.17% D. 6.66% to 15.34%

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116. A 40-year-old woman visits the clinic complaining of fatigue. She had recently been treated for an infection. Her
laboratory values are RBC 1.8 × 106/μl, Hb 5.2 g/dL, hematocrit (Hct) 15, WBC 7.6 ×103/μl, platelet count 320,000/μl,
mean corpuscular volume (MCV) 92 fL, and reticulocyte count 24%.What is the most likely explanation for this
presentation?A) Aplastic anemiaB) Hemolytic anemiaC) Hereditary spherocytosisD) B12 deficiency
117. A person’s normal tidal volume is 400 ml with a dead space of 100 ml. The respiratory rate is 12 breaths/min.
The person is placed on ventilator for surgery and the tidal volume is 700 with a rate of 12. What is the approximate
alveolar Pco2 for this person?
A) 10 B) 20 C) 30 D) 40
118. A female athlete who took testosterone-like steroids for several months stopped having normal menstrual
cycles. What is the best explanation for this observation?
A) Testosterone stimulates inhibit production from the corpus luteum
B) Testosterone binds to receptors in the endometrium, resulting in the failure of the endometrium to develop during
the normal cycle
C) Testosterone binds to receptors in the anterior pituitary that stimulate the secretion of FSH and LH
D) Testosterone inhibits the hypothalamic secretion of GnRH and the pituitary secretion of LH and FSH
119. A man in his twenties presents in the emergency room with shortness of breath and fatigue. He is also very pale.
Two days earlier he was given penicillin for an infection. He had penicillin v previously without problems and stated
that he had “no allergy” to penicillin. Laboratory testing shows that antibodies to penicillin are present in the patient’s
serum and that he is breaking down his own red blood cells. He is diagnosed with immune hemolytic anemia. The
patient has which type of hypersensitivity reaction?
(A) Type I (B) Type II (C) Type III (D) Type IV (DTH)
120. A 5-year-old girl attended a birthday party at a local fast food restaurant. About 48 hours later, she developed
cramping abdominal pain and a low-grade fever and had five episodes of loose, bloody stools. She is taken to a local
emergency department the next evening because the diarrhea has continued, and she now appears pale and lethargic.
On presentation, she has a temperature of 38 C, and she is hypotensive and tachycardia. The abdominal examination
reveals tenderness in the lower quadrants. Laboratory work is remarkable for a serum creatinine of 2.0 mg/dL, a serum
hemoglobin of 8.0 mg/dL, thrombocytopenia, and evidence of hemolysis. What is the most likely pathogen causing
this child’s illness?
(A) Escherichia coli O157:H7 (B) Salmonella enterica subspecies enterica serotype Typhimurium
(C) Enteropathogenic Escherichia coli (D) Edwardsiella tarda
121A hospitalized patient who had an indwelling urinary catheter develops fever, chills, suprapubic pain and difficulty
voiding 48 hours after the catheter is removed. His bladder appears obstructed, and he has white blood cells and
bacteria on a urinalysis. Cystoscopy reveals a large bladder stone, and the urine culture grows

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greater than 10,000 CFU/mL of a short, irregular gram positive rod. The most likely organism causing this infection is
(A) Corynebacterium urealyticum (B) Nocardia brasiliensis
(C) Actinomadura D) Erysipelothrix
122. A 60-year-old-man has a 5-month history of progressive weakness and a weight loss of 13 kg along with
intermittent fever, chills, and a chronic cough productive of yellow sputum, occasionally streaked with blood. A
sputum specimen is obtained, and numerous acid-fast bacteria are seen on the smear. Culture of the sputum is positive
for Mycobacterium tuberculosis. Which treatment regimen is most appropriate for initial therapy?
(A) Isoniazid and rifampin (B) Sulfamethoxazole–trimethoprim and streptomycin
(C) Isoniazid, rifampin, pyrazinamide, and ethambutol (D) Isoniazid, cycloserine, and ciprofloxacin

123. A 41-year-old HIV-infected male who had refused antiretroviral therapy is diagnosed with
Pneumocystis jiroveci infection. This patient
(A) Probably has a CD4 T-cell count below 200 cells/ L(B) Is at elevated risk for lung cancer
(C) Has a life expectancy of about 5 years(D) Probably has declining levels of plasma viremia

124. An outbreak of mild intestinal distress, sleeplessness, perinatal itching, and anxiety has broken out among
preschool children in a private home. The most likely cause of this condition is
(A) Trichomonas vaginalis(B) Enterobius vermicularis(C) Ascaris lumbricoides(D) Necator americanus
125. A previously healthy 23-year-old woman recently returned from her vacation after visiting friends in
Finfinnee(Addis Ababa). She complained of severe headaches, saw “flashing lights,” and had a purulent nasal
discharge. She was admitted into the hospital with a diagnosis of bacterial meningitis and died 5 days later.Which of
the following parasites should have been considered in the diagnosis? She had no prior history of travel outside of
Finfinnee(Addis Ababa).
(A) Toxoplasma gondii(B) Strongyloides stercoralis(C) Entamoeba histolytic (D) Naegleria fowler
126. Young black man entered his physician's office complaining of bloating and diarrhea. His eyes were sunken and
the physician noted additional signs of dehydration. The patient's temperature was normal. He explained that the
episode had occurred following a birthday party at which he had participated in an ice cream eating contest. The
patient reported prior episodes of a similar nature following ingestion of a significant amount of dairy products. This
clinical picture is most probably due to a deficiency in:

A. isomaltase. B. pancreatic α-amylase. C .sucrase. D. lactase.

127. In preparation for a trip to an area of Limmu Gallia where malaria is endemic, a young man is given primaquine
prophylactically. Soon thereafter, he develops a hemolytic condition. The most likely cause of the hemolysis is a less-
than-normal level of which of the following?

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A. Glucose 6-phosphateB. Oxidized form of NADC. Reduced form of glutathioneD. Ribose 5-phosphate
128. Aspirin-induced asthma (AIA) is a severe reaction to nonsteroidal anti-inflammatory drugs (NSAIDs)
characterized by bronchoconstriction 30 minutes to several hours after ingestion. It is seen in as many as 20% of adults.
Which of the following statements best explains the symptoms seen in patients with AIA?
A. NSAIDs inhibit the activity of the CFTR protein, resulting in thickened secretions that block airways.
B. NSAIDs inhibit COX but not lipoxygenase, resulting in the flow of arachidonic acid to leukotriene synthesis.
C. NSAIDs activate the COX activity of PGH synthase, resulting in increased synthesis of prostaglandins that
promote vasodilation.
D. NSAIDs activate phospholipases, resulting in decreased amounts of dipalmytoylphosphatidylcholine and alveolar
collapse (atelectasis).

129. A 39-year-old woman is brought to the emergency room complaining of dizziness. She recalls getting up early
that morning to do as much shopping as possible and had skipped breakfast. She drank a cup of coffee for lunch and
had nothing to eat during the day. She met with friends at 8 p.m. and had a drink at the bar. She soon became weak and
dizzy and was transported to the hospital. Following examination, the patient was given orange juice and immediately
felt better. Which one of the following best completes this sentence? “The patient has”:A. blood glucose greater than
70 mg/dl.B. elevated insulin.C. elevated glucagon.D. elevated liver glycogen.
130. A 35-year old sedentary male patient weighing 120 kg was experiencing angina (chest pain) and other signs of
coronary artery disease. His physician, in consultation with a registered dietician, conducted a 3-day dietary recall. The
patient consumed an average of 585 g carbohydrate, 150 g protein, and 95 g fat each day.
In addition, he drank 45 g alcohol. The patient
(A) consumed between 2,500 and 3,000 kcal per day.
(B) had a fat intake within the range recommended in current dietary guidelines (i.e., year 2000).
(C) consumed 50% of his calories as alcohol.
(D) was deficient in protein intake.
131. A patient who is supposed to be taking a drug once a day gets confused and for a couple of days takes excessive
daily doses , leading to toxicity. The drug has a mean plasma half-life of 40 hours .Right now the patient’s plasma
concentration of the drug i s 6 mcg/mL.The usual plan in this case is to have the patient skip one or several doses daily
until the blood level first enter the therapeutic and nontoxic range which in this case is 0.8 mcg/mL. Assume the drug
is eliminated by first order kinetics, how many doses should be withheld?A . 1 B. 2 C. 3 D. 5
132. A 54-year-old woman with severe hypercholesterolemia is to be treated with a combination of niacin and
atorvastatin. With this drug combination, it is important that the patient be monitored closely for signs of(A)
Agranulocytosis (B) Gallstones(C) Lactic Acidosis (D) Myopathy

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133. A patient receiving a class I antiarrhythmic agent on a chronic basis complains of fatigue, low-grade fever, and
joint pain suggestive of systemic lupus (SLE).The patient is most likely receiving(A) Lidocaine
(B) Procainamide(C) Quinidine (D) Flecainide
134. A 48-year-old hypertensive patient has been successfully treated with a thiazide diuretic for the last 5years. Over
the last 3 months, his diastolic pressure has steadily increased, and he was started on an additional antihypertensive
agent. He complains of several instances of being unable to achieve an erection and not being able to complete three
sets of tennis as he once did. Which is the likely second antihypertensive medication?

A. Captopril. B. Losartan. C. Metoprolol. D. Minoxidil. E. Nifedipine

135. Suppose you are a pharmacist working in the quality control to ensure the safety and efficacy of drugs before
they are made available on market. Which of the following analysis result would you certify having no significant risk
on the health of your society with scientific tolerance limit?

A) A drug of 1.5gram daily dose with 225mg impurity B) A drug of 1.5gram daily dose with
1.0mg impurity
C) A drug with 2.0gram daily dose with 300mg impurity D) 2gm drug with daily dose with 2gm
impurity
136. Which of the following statement/s clearly shows the difference between accuracy and precision?
A) Accuracy is degree of closeness between series of measurements
B) Precision is the closeness between the mean of measurements and standard value for the measurements
C) Precision is the measure of the closeness among many series of measurements
D) Both accuracy and precision describe the level of our exactness on measurements
137. If the accelerated stability test and long term test at 12 months of a particular drug is ok with regard to its
stability and chemical composition, the pharmacist can say the shelf life of a drug is _
A) Two years B) 3.5 years C) 18 months D) 30 months
138. Mr Gammada is 45years old man working in factory. He was recently diagnosed with rheumatoid arthritis and
have been dispensed with drug of pka=8.3 and PH=5.3(weak acid in nature) to get relief. Considering the
drug to be ionized in his intestine without any other physiological activity, what percent (%) of the drug is
ionized in his body at this condition?
A) .1% B) 99.1% C) 95% D)100%

139. Mr. Magarsaa is a pharmacist working in drug analysis and laboratory control area and had done the following
situation to check the physical and chemical properties of a drug. He titrated 50ml of acetic
acid( Pka=1.75*10~5 ) and 0.25 molarity with NaOH 0.5M at 25 degree Celsius. 116. Which of the following
statements clearly explain about the nature of the above Titration?(equimolar ratio reaction)

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A) it is Titration of weak acid with weak base and its equivalent volume is attained at 25ml
B) The pH of the Titration curve increases rapidly at the starting point than at equivalent volume
C) The PH of the Titration increases more rapidly at equivalent volume than at the initial point.
D) acetic acid presents in excess after the equivalent volume is attained.
140. Mr x and y are working in the drug quality control and want to give TOT about the quality assurance as well as
quality control and started from the definition of the terms. Though the term seems similar, which of the following is
the correct relationship?
A) Quality control is meant to prevent defects in the manufacturing process whereas quality assurance is to
detect defects in the pharmaceutical products
B) Quality assurance is preventive process whereas quality control is corrective process
C) Quality assurance is a single step process whereas quality control is undertaken in entire cycle of
production
D) Quality assurance and quality control have the same meaning
141.Which of the following is correct about systematic error?
A) It is also called determinate error C) It is also called indeterminate error
B) C) It is not avoidable can be neither corrected nor eliminated. D) Can be avoided but once occurred
cannot be eliminated
142. An infusion stated to contain 0.95% w/v NaCl was diluted so that its Na content could be determined by flame
photometry. The following dilutions were carried out

₾ (i) 10 ml of the sample was diluted to 250 ml with water.


₾ (ii) 10 ml of the diluted sample was diluted to 200 ml with water.
 The sample was found to contain 0.74 mg/100 ml of Na.
 Atomic weights: Na = 23, Cl = 35.5 .The % w/v of NaCl present in the infusion will be
A)370mg/100ml B)0.91mg/Ml C) 0.91% D)99.1%
143. Ato Worku is pharmacist working in the laboratory and want to check the molarity of the 37% w/w HCL.It was
stated on the bottle that the density of the solution is 1.19g/ml.what Is the molarity of the above stated
solution?(mol.weight of HCL=36.46).
A) 12.08M B) 440.3M C) 36.64M D) 20M
144. Which of the following is correct about the types of acid- base Titration and mainly used indicators?
A) strong acid –strong base..>methyl orange
B) weak acid-strong base.….> methyl orange
C) strong acid- strong base…> phenolphthalein
D) all indicators can be used for all types of titration by keeping the environmental factors constant
145.Patients in northern part of Ethiopia believe that injections are more effective than any oral
preparations; especially tablets & capsules. The above case is an example of:
A. Descriptive C. Normative
B. Analytic D. a & b
146. In care ethics, ethical decisions are made by focusing on:

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A. Virtue. C. Persons
B. Actions. D. The community.
147. According to FDA Compliance Policy Guide on Pharmacist Compounding, pharmacists may NOT
compound which of the following?
A. Drug approved by FDA but removed from the market due to lack of demand
B. A compounded drug request made over the phone
C. Drugs containing ingredients that meet official compendia standards
D. Drugs approved by FDA but removed from the market due to safety concerns
E. Drug that has similar ingredients to one that is approved by FDA and commercially available 148.Of
the following laws which one provided the basis for categorizing drugs as prescription only and
non-prescription drugs?
A. Food, drug & cosmetic Act C. Tort Law
B. Control drug Act D. Poisons Act
149. Which controlled substances Schedule includes drugs that have a high potential for abuse, have an
approved medical use, require a written prescription, and may not be refilled?
A. Schedule I C. Schedule III
B. Schedule II D. Schedule IV
150. Belonging to a profession brings a range of benefits but it also attracts a range of obligations. Which of the
following is not an obligation associated with being a professional?
A. To act in the best interests of patients.
B. To apply a high degree of skill and knowledge to their work.
C. To be objective and non-judgmental.
D. To use specialized information and operate under a monopoly.
151.All of the followings are laws of private product ownership, except?
A. Commercial law C. Trade mark law
B. Private law D. none
152.A Pharmacist receives a prescription for Oxytocin and notices a few errors. What information on the
prescription may the pharmacist NOT change??
A. Spelling of the drug name C. Date of prescription issue
B. Strength of drug D. Spelling of the patient's name

153.A drug is deemed to be adulterated if:-


A. It doesn’t bear the name of the agent.
B. It consists in whole or in part any filthy, putrid or decomposed substance.
C. If it fails to meet compendia standards.
D. All E. all except ‘A’
154. Which of the following employees of the pharmacy are allowed to sell over the counter
pseudoephedrine assuming all of other applicable laws are followed?
i. Pharmacist
ii. Licensed Pharmacy Technician
iii. Pharmacy clerk/cashier
A. i only D. ii and iii only
B. iii only E. i, ii, and iii only
C. i and ii only
155. Manufacturers of pharmaceutical must be controlled legally to:
A. Ensure the quality, safety & efficacy of pharmaceutical manufactured.
B. Prevent the manufacture of counterfeit.

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C. Prevent adulterated and substandard pharmaceutical.


D. all
156.A drug will be prescription only if it depicts one of the following.
A. It is habit forming C. It is a new drug
B. It is not safe for self-medication D. all
157.Free sample of narcotic drugs & psychotropic substances are supplied only to persons qualified to
prescribe medical product &/or pharmacy personnel for advertisement purpose.
A. True B. False
158.A pharmacist misfiles a patient's prescription during a refill. The pharmacist admits that he made the mistake,
however argues that the patient had been taking the medication for over 5 years and should have known that
the medication looked different and not consumed it. The courts agree that both the pharmacist and patient are
negligent, if the court is in an area where only contributory negligence is present which of the following states
is most true?
A. The pharmacist is responsible for all damages
B. The patient is responsible for all damages
C. No damages would be awarded since damages are all or none
D. The patient would be 25% responsible and the pharmacist 75%
E. The patient would be 25% responsible, pharmacist 40%, and the pharmacy 35%.
159. Mrs. Smith and Mrs. Thompson are neighbors that both use Friendly Pharmacy for their prescription needs.
Friendly Pharmacy misfiled one of Mrs. Thompson’s prescriptions. Mrs. Thompson informed Mrs. Smith of
the error. Mrs. Smith was outraged after learning about the error and now desires to sue Friendly Pharmacy.
Would Mrs. Smith likely be successful in proceeding with a lawsuit?
A. Yes. Mrs. Smith has a right to sue the pharmacy for any errors Friendly Pharmacy makes to help
protect society.
B. Yes. Mrs. Smith has a right to sue the pharmacy because Mrs. Thompson informed her of the
error.
C. No. Mrs. Smith had no harm caused to her by the error and has no interest to protect with a lawsuit.
D. No. Mrs. Smith only learned of the error through her neighbor and not directly through the
pharmacy.
160. When a practitioner, other than a pharmacist, dispenses a prescription drug, which of the following may
he/she omit from the label?
A. Name of the drug C. Directions for use
B. Date of dispensing D. Name of the Patient
161.A profession can be distinguished from other occupations in terms of their use of knowledge.
A. Professions have access to a body of specialized knowledge that is not available to by those outside the
profession.
B. Professions rely on a body of specialized knowledge which is not accessible to by those outside the
profession.
C. Professions rely on a body of specialized knowledge which is not easily understood by those outside
the profession.
D. Professions apply specialized knowledge which is not available to those outside the profession. 162.When a
person is allowed to die, death is a result of an act of commission e.g. administering a lethal
dose of medication to a patient; the commission is an instance of ?
A. Passive Euthanasia C. Non- voluntary Euthanasia
B. Active Euthanasia D. a & c
163.For consent to be valid, it must be፡
A. The person consenting must have the capacity to make their decision.

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B. Voluntary
C. Informed
D. All
164.Which of the following statement(s) is/are correct?
A. Beneficence—is doing or promoting good/the provision of benefits. This principle is basis for all
health care providers.
B. Act utilitarianism: suggests that people choose actions that will in any given circumstances
increase the overall good.
C. Confidential information can only be disclose if the patient gives explicit consent or if
expressly provided for in the law.
D. For clinical research, written consent is a must.
E. All
165.A pharmacist is favorably impressed with the effectiveness of the new aerosol medication for the
treatment of Asthma and wishes to dispense it to a 13- year old girl with recurrent Asthma attack. She is
eager to try the new medication. However, her mother, who accompanies her to clinic, asks that she not
receive the medication. The pharmacist’s most appropriate action would be
A. Politely but firmly dispense the medication in the health interests of the girl despite the protest of the
mother.
B. Not dispense the medication because the mother has not consented to this treatment
C. Not dispense the medication because the adherence is jeopardized the mother’s lack of
support.
D. Provide a free sample inhaler and ask a girl and her mother to try it out before deciding to decline
the prescription.
166.A Pharmacist calls the state health department because she believes a child she recently dispensed a new
drug is experiencing an adverse reaction. She is unsure of the lot number or the batch as she received the
drug from two different pharmaceutical companies. Which of the following chart documentations of drug is
required?
A. Name of the drug and date of dispensing
B. Name of the drug, manufacturer, and date of dispensing
C. Name of the drug, lot number, manufacturer, and date of dispensing
D. Name of the drug, lot number, manufacturer, date of dispensing, and physician name
167.A 34-year- old man with a history of severe asthma presents to the Emergency Department with sudden
onset difficulty in breathing. He is given succinylcholine for intubation. Shortly after intubation, he
develops muscle rigidity and hyperthermia.Which of the following is the most appropriate next stepin
treatment?
A. Bromcriptine
B. Dantrolene
C. IV antibiotis
D. Physostigmine
168.A 35-year-old previously healthy woman comes to the OPD due to 3 days of fever and malaise. The patient's
symptoms started after returning from a 2-week vacation to the Dire Dawa, where similar problems had been
noticed. For the past day, she has also had marked pain in her hand and wrist joints. Temperature is 39.4 C,
blood pressure is 110/70 mm Hg, and pulse is 98/min. She has a macular skin rash on her body and mild
cervical lymphadenopathy. There are no oral ulcers. Musculoskeletal examination shows swelling and
tenderness of bilateral hand, wrist, and ankle joints.Which of the following is the most likely diagnosis?
A. Acute hepatitis B infection
B. Chikungunya fever
C. Yellow fever
D. Dengue fever
The following scenario applies to questions 169 and 170.
169.A 33-year-old woman presents to your pharmacy for antibiotics emergency with8 days of subjective fever,
headache, sore throat, and malaise. She states that acetaminophen and ibuprofen have failed to help her
symptoms. She recently returned from West Africa.

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What is the likely diagnosis for this case?


A. Ebola Virus Disease (EVD).
B. pandemic influenza(Pan flu)
C. COVID-19
D. MERS-CoV
170.What type of isolation does this patient require?
A. Airborne
B. Contact
C. Contact and droplet
D. Contact and airborne
171.A 45-year old woman presents to the pharmacy asking for analgesia with a compliant of fever and cough of 2
days duration. He recently arrived to Addis Ababa from China on the beginning of March 27, 2020.
What is the most likely explanation of this case?
A. Ebola Virus Disease (EVD).
B. Hanta virus
C. Chinese Virus
D. COVID-19
172.A 30-year old man is being diagnosed with HIV/AIDS. You then had been consulted for the
initiation of ART.
What is the preferred first line regimen,as per the latest national ART guideline?
A. Tenofovir +Lamivudine + Efaverenz
B. Zidovudine +Lamivudine + Efaverenz
C. Zidovudine +Lamivudine + Doultegravir
D. Tenofovir +Lamivudine + Doultegravir
173. You are designing a clinical trial to test the use of a novel anti-viral drugs for the treatment of
COVID-19. Which of the following statements regarding the design of the trial is true?
A. An optimal study design would assign many patients to antiviral and compare their
outcomes to the outcomes o prior (historical) patients’ not taking antiviral.
B. If the trial returns a positive result (antiviral is superior to placebo), that means that any patient
with COVID-19 would benefit from clotbegone therapy.
C. Population selection or the trial enrollment is not important as long as care full attention to
randomization and blinding is observed.
D. The advantage of performing a randomized clinical trial of antiviral over a prospective
observational study of antiviral is the avoidance of treatment selection bias.
174. Patients taking which of the following drugs should be advised to avoid drinking grape fruit juice?
A. Amoxicillin
B. Aspirin
C. Atorvastatin
D. Sildenafil
175. Mr. Brook’s has been a customer to your pharmacy for over 20 years. Recently, he was diagnosed with
Parkinson’s disease, an almost universally fatal degenerative neurologic condition. In consultation with his
neurologist, you have started him on a high dose of a new medication, Drug X, to alleviate muscle spasms.
However, although Mr. Brook’s muscle spasms have improved drastically, he is experiencing dry mouth and
dry eyes, side effects that were not described in very large clinical trials of Drug X. A recent post marketing
study of Drug X was released showing that patients with Parkinson’s disease taking it live, on average, 14
days less than patients not taking it. As you discuss the plan regarding Drug X with Mr. Brooks, which
statement would be valid?
A. “A recent study shows that patients taking Drug X die sooner, on average, than those not taking it. I
want to discuss your thoughts on continuing Drug X, perhaps at a lower dose, versus stopping it.”
B. “A recent study shows that patients taking Drug X die sooner, on average, than those not taking it. I
recommend stopping it, and I anticipate the drug will be discontinued soon.”
C. “I you’re having side effects at the high dose, it’s certain that you’ll have the same side effects at a
lower dose.”

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D. No discussion is needed given the post marketing data. You should stop Drug X and report the new
side effect to the Ethiopian. Food and Drug Administration (FDA).
176. The 2008 WHO World Health Report describes how a primary healthcare approach is necessary “now
more than ever” to address global health priorities. All of the following areas of reform were highlighted in
the report, EXCEPT :
A. Drug development
B. Public policy
C. Service delivery
D. Universal health coverage
177. Which of the following is projected to cause the most deaths in low- and middle-income countries in 2030?
A. Cancer
B. Cardiovascular disease
C. HIV/AIDS, B, malaria, and other infectious diseases
D. Intentional injuries
E. Road traffic accidents
178. You are evaluating the vitamin D intake or a 32-yearold woman who is not pregnant or lactating. It is found
to be below the recommended dietary allowance (RDA), although a serum level of vitamin D has been
measured previously as within normal limits. Which statement is true with regard to this scenario?
A. Dietary reference intakes (DRI) would have been a better tool to determine if her nutrient intake
was adequate.
B. Given the normal serum level of vitamin D, there is no reason to increase her intake of vitamin D.
C. RDA is not the best measure for evaluating the nutrient requirements of this individual.
D. All of the above statements are true with regard to this scenario.
179. You are working in a pharmaceutical industry as industrial pharmacist and you want to manufacture tablets
using moisture and heat stable, fluffy powder. Which method do you choose as the most suitable method to
manufacture the tablets using this powder?
A. Direct compression B. Dry granulation C. Wet granulation D. Indirect compression
180. While you are manufacturing a tablet in a pharmaceutical industry you have faced a tablet processing problem
called lamination, which means separation of a tablet into two or more distinct layers. How could you avoid
this processing problem?
A. By using deep concave punches C. By using flat punches
B. By using curved punches D. By using convex punches
181. During when you make quality evaluation for the tablet that you already have manufactured, it fails to pass
the weight variation test, this might be due to poor flow of the powder through the hopper during the die
filling process. What measure shall you take to correct this problem?
A. Addition of glidant or an increase in the amount already present
B. Addition of adherent or an increase in the amount already present
C. Addition of binders or an increase in the amount already present
D. Addition of disentigrant or an increase in the amount already present
182. You want to test percentage friability of tablets; suppose, you weighed 20 tablets and the weight become 10g.
After the tablets revolved for 4 minutes (25rpm) in a friability tester and dusted, their weight becomes 8.5g.
What is the percentage friability of the tablet? do you accept or reject the tablet?
A. 1 % and accept B. 1.5 % and reject C. 10% and reject D. 15% and reject
183. If you are working in a pharmaceutical store and observed hard gelatin capsules become distorted and lose
their rigid shape or become brittle and broken when handled, what would you do to solve this problem?

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A. Store in an environment free from excessive humidity or dryness


B. Store in an environment of excessive humidity or dryness
C. Store in an environment of excessive humidity
D. Store in an environment of excessive dryness

184. After a pharmacist filled an empty hard gelatin capsule extemporaneously and dispensed to the patient, the
patient complained by the bitter test of the capsule. During capsule filling process the pharmacist missed one
final step. What is that step that makes the capsule bitter?
A. Developing and preparing the formulation C. Filling the capsule shell
B. Cleaning and polishing the filled capsules D. Capsule sealing
185. Suppose, you are working in a compounding room and you have a prescription order to prepare an ointment.
The prescribed medicament is insoluble in the base that you are going to use for preparation of the ointment.
Which method do you use for preparation of this ointment?
A. Fusion B. Trituration C. Melting D. simple mixing
186. In a sterile product manufacturing unit, a pharmacist is evaluating quality of a sterile product. In one of his in
vitro test he used Litmus Amebocyte Lysate(LAL) at 370c and a firm gel is formed. What is your conclusion
from this test?
A. The product is free from micro organisms and should pass the quality evaluation
B. The product is free from pyrogen and should pass the quality evaluation
C. The product is not free from micro organisms and should fail the quality evaluation
D. The product is not free from pyrogen and should fail the quality evaluation

187. A 72 year old patient comes to your pharmacy to buy paracetamol for his head ache. Which paracetamol
would you suggest to dispense for this patient?
A. Tablet B. Effervescent tablet C. Capsule D. Suppository
188. If you need to prepare solution formulation by dissolving gases in a liquid solvent, in which condition would
you prepare to increase solubility of gases in the liquid solvent?
A. High temperature B. low temperature C. low pressure D. by addition of salt
189. You have prepared a solution dosage form and the solution is precipitated up on storage for months. This
might be due to missing addition of one of an excipient. Missing addition of which excipient do you think is
the factor that decrease solubility or make the solution to precipitate?
A. Buffering agent B. Preservatives C. Antioxidants D. Chelating agent
190. If you want to prepare dosage form for internal use which container is that which you shouldn’t use as a
primary packaging material due to its toxicity?
A. Tin B. Lead C. Glass D. Aluminum
191.A pharmacist has got a prescription order to prepare pharmaceutical emulsion for internal use, which
surfactant would you recommend to be used as an emulsifying agent for internal use?
A. Anionic B. Cationic C. None ionic D. Amphoteric

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192.After you have manufactured an emulsion, you want to test the type of emulsion you made. Then, when you
make conductivity test the emulsion conduct electricity (the bulb glows). What is the type of emulsion you
made?
a. Oil in water B. Water in oil C. Oil in water in oil D. Which is not emulsion at all
193.A pharmacist needs to prepare a pharmaceutical dosage form. During his preparation he provides an active
ingredient and excipients. But, he worried if there is any toxicity or incompatibility among different excipients.
What would you recommend for the pharmacist?
a. To use multifunctional excipients C. To increase amount of excipients
b. To use unifunctional excipients D. To increase number of excipients
194.The initial concentration of a drug is 0.64 and rate constant is 0.00068 hr-1. Assuming the decomposition is
zero order, what is the half life of the drug?
A. 290 hr C. 390 hr
B. 471 hr D. 571 hr
195.A solution of drug contained 680 units per ml when prepared. It was analyzed after a period of 70 days and
was found to contain 400 units per ml. assuming the decomposition is first order, at what time will the drug
have decomposed to one half of its original concentration?
A. 68 days C. 92 days
B. 78 days D. 60 days
196.Oxidation is one of the factors that affect stability of pharmaceutical products. As a pharmacist you should
take all of the following precaution to minimize oxidation during manufacturing and storage of
pharmaceuticals except.
A. The oxygen in pharmaceutical containers should be replaced with Nitrogen or carbon dioxide
B. Contact of the drug with heavy-metal ions should be avoided
C. Storage should be at elevated temperatures
D. Antioxidants should be included in the formulation
197.A 30 years old nursing mother diagnosed with thyroid cancer. The Oncologist prescribed Sodium iodide I 131
for her thyroid cancer. As pharmacist you have to counsel the patient all of the following except.
a. Breast-feeding is possible during treatment with radiopharmaceuticals
b. Recommended the women not to become pregnant for a year after treatment
c. Radiopharmaceuticals usually are not recommended for use during pregnancy
d. It is important to drink plenty of liquids and to urinate often after treatment
198.A physician wants to prescribe NSAIDs for a patient with local muscle inflammation. The patient has a
history of peptic ulcer. Which rout provide a sustained concentration of drug for absorption and suitable for
this patient?
A. Transdermal B. Oral C. Intravenous D. Rectal

199. Abel holds a management position within his organization. His tasks as a manager include maintaining a focus toward long-
term issues that may impact the organization as

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well as developing appropriate goals to guide the organization to best paths. Based on the above scenario
Abel is most probably what type of manger?
A. Firstlevel C. Top level

B. Middlelevel D. Operational
manager

200. Mrs. Hannah John as the manager of an organization, she tries to change the existing organizational
structureintoanotherwhichisthemostpossiblyfittedforherorganization. Consequently she divided into the
Southwest, Midwest, southern, northern, and western regions. Therefore, based on the above scenario
what would be the departmentalization she used for the purpose of division?
A. Product C. Process

B. Geographic D. Outcome

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