There is currently no general agreement as to which mechanism is necessary for initiating automaticity or, in other words, which ionic and/or cellular mechanism specifically confers automaticity to pacemaker cells.
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2008. Matteo E. Mangoni, Joël Nargeot. "Genesis and Regulation of the Heart Automaticity". 10.1152/physrev.00018.2007
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æ å½channel: ERG1-3