Cell Structure-Group #4
Cell Structure-Group #4
CELL STRUCTURE
GROUP MEMBERS
ANGIE C ÓRD OVA
AND R EA MOROC HO
NÁTHA LY S ÁNC HEZ
ED UA R D O U LLAURI
TEACHER
LC D A. MARIB EL B A R R E T O
7TH "A"
What is a cell?
The cell (from Latin cella, meaning "small room") is the basic structural,
functional, and biological unit of all known organisms. A cell is the smallest unit
of life. Cells are often called the "building blocks of life". The study of cells is
called cell biology, cellular biology, or cytology.
Cells consist of cytoplasm enclosed within a membrane, which contains
many biomolecules such as proteins and nucleic acids. Most plant and animal
cells are only visible under a microscope, with dimensions between 1 and
100 micrometres.
Historic facts
In a 1665 publication called Micrographia, experimental scientist Robert
Hooke coined the term “cell” for the box-like structures he observed when
viewing cork tissue through a lens and began the scientific study of cells,
known as cell biology.
In the 1670s, van Leeuwenhoek discovered bacteria and protozoa. Later
advances in lenses, microscope construction, and staining techniques
enabled other scientists to see some components inside cells
Cell theory was eventually formulated in 1839. This is usually credited
to Matthias Schleiden and Theodor Schwann. However, many other
scientists like Rudolf Virchow contributed to the theory. It was an important
step in the movement away from spontaneous generation.
Cell theory
Is the historic scientific theory, now universally accepted, that living organisms
are made up of cells, that they are the basic structural/organizational unit of all
organisms, and that all cells come from pre-existing cells. Cells are the basic unit
of structure in all organisms and also the basic unit of reproduction.
The three tenets to the cell theory are as described below:
1. All living organisms are composed of one or more cells.
2. The cell is the basic unit of structure and organization in organisms.
3. Cells arise from pre-existing cells.
Eukaryotic cells are found in plants, animals, fungi, and protists. They
range from 10–100 μm in diameter, and their DNA is contained within a
membrane-bound nucleus. Eukaryotes are organisms containing
eukaryotic cells. It is believed that eukaryotes have been evolved from the
prokaryotes.
Plasma membrane
Cytoplasm
Ribosomes
Nucleus No Yes
STRUCTURE CELL
Cell has non living outer layer called cell wall found only in plant cells below cell
wall is cell membrane. Cell membrane encloses protoplasm.
Protoplasm has semi fluid matrix called cytoplasm and large membrane bound
structure called nucleus.
Cytoplasm has many membrane bound organelles like endoplasmic reticulum,
golgi bodies, mitochondria, plastids and vacuoles.
They also have non membrane bound structures called ribosomes and
centrosomes
Cytoplasm without cell organelles are called cytosol.
How do plant and animal cells differ?
Both plant and animal cells are
eukaryotic, so they contain
membrane-bound organelles like
the nucleus and mitochondria.
However, plant cells and animal
cells do not look exactly the same
or have all of the same organelles,
since they each have different
needs. For example, plant cells
contain chloroplasts since they
need to perform photosynthesis,
but animal cells do not.
We have animal cell and plant cell
Animal cell: Are smaller measuring 10-30 micrometers in length, are typically
round or irregular in shape, they have no cell wall, have the nucleus in center,
many vacuoles, cannot synthesis nutrients and has no plasmodesmata.
Plant cell: Are larger measuring 10 – 100 micrometers in length, are typically
rectangular or cubic in shape, they have cell wall, have nucleus on the side, one
vacuole, synthesizes nutrients and has plasmodesmata.
CELL WALL
A cell wall is a structural layer surrounding
some types of cells, just outside the cell
membrane. It can be tough, flexible, and
sometimes rigid. It provides the cell with
both structural support and protection, and
also acts as a filtering mechanism. Cell
walls are present in most prokaryotes in
algae, fungi and eukaryotes including
plants but are absent in animals. A major
function is to act as pressure vessels, protection, mechanical support and
preventing over-expansion of the cell when water enters.
CELL MEMBRANE
The cell membrane (also known as the plasma membrane, or cytoplasmic
membrane, and historically referred to as the plasmalemma) is the
semipermeable membrane of a cell that surrounds and encloses its contents of
cytoplasm and nucleoplasm. Separates the cell from the surrounding interstitial
fluid, the main component of the extracellular fluid.
The cell membrane consists of a lipid bilayer, including cholesterols that sit
between phospholipids to maintain their fluidity at various temperatures. Also
contains membrane proteins, including
integral proteins that go across the
membrane serving as membrane
transporters, and peripheral proteins
that loosely attach to the outer
(peripheral) side of the cell membrane,
acting as enzymes shaping the cell.
The cell membrane controls the
movement of substances in and out of
cells and organelles. Also of movement
of molecules across it like diffusion,
osmosis, active transport, phagocytosis and pinocytosis.
Cytoplasm
The word was coined by the ‘Rudolf von Kolliker‘ in the year 1863, as the
synonym of protoplasm. The term ‘Cyto‘ means cell and ‘Plasm‘ means liquid, so
Cytoplasm is the transparent material, percent between the cell membrane and
the nucleus of the eukaryotic cell. It is the semi-fluid, translucent material and
constitutes all the cell organelles, metabolic wastes, proteins, food reserves.
As different organelles have different functions like mitochondria, which is called
the ‘powerhouse of the cell’ is known for producing energy, Golgi is known for
protein sorting, endoplasmic reticulum is known for transporting material,
cytoskeleton provides the structure and rigidity to the cell and so on. Therefore,
these organelles are supported by the cytoplasm to work smoothly and
faultlessly.
The cytoplasm also surrounds the nucleus. It contains the cytosol or cytoplasmic
matrix, which is the aqueous substance and is differentiated into outer ectoplasm
Protoplasm
The word Protoplasm is a Greek word, which means “first thing formed“. It is jelly-
like substance, where numerous chemical, as well as biological activities, takes
place. Therefore, protoplasm is said as the ‘physical basis for life’ and part of the
living cell. It contains about 90% water, salts, proteins, lipids, and carbohydrates.
It is selectively permeable, elastic, granular, colloidal, colourless substance.
Protoplasm is said as the living substance of a cell. Although in modern biology
protoplasm is not used commonly, as it does not have the full proof origin and so
these days only cytoplasm, organelles and nucleus is studied.
BASIS FOR
CYTOPLASM PROTOPLASM
COMPARISON
Meaning The semi-solid material, present Protoplasm is called as the living substance
netween the nucleus and the cell of the cell, and it surrounds the cell
membrane. Mainly made up of water membrane, the nucleus and the cytoplasm.
and is responsible for the half of the So we can say protoplasm constitute the
cell's volume. cytoplasm as well as the nucleus.
Structural Cytoplasm contains organelles like Protoplasm contains cytoplasm as well as the
difference Golgi body, Endoplasmic reticulum, nucleus; thus we can say that protoplasm =
Mitochondria, Ribosomes, nucleus + cytoplasm.
Lysosomes, etc., but not the
nucleus.
It contains Cytoplasm is one of the constituents Protoplasm is thick, viscous fluid which is
of the protoplasm, it is jelly like fluid translucent and is made up of proteins, lipids,
and contains water, metabolic carbohydrates, nucleic acid and inorganic
wastes, proteins, food reserves. salts. It is the site for various biological and
chemical activities.
The Nucleus
The nucleus, which has a diameter of about 5 m, is a prominent structure in the
eukaryotic cell. The
nucleus is of primary
importance because
it stores the genetic
material DNA which
governs the
characteristics of the
cell and its metabolic
functioning. Every
cell in the same
individual contains
the same DNA, but,
in each cell type,
certain genes are
turned on and certain
others are turned off.
Activated DNA, with RNA acting as an intermediary, specifies the sequence of
amino acids when a protein is synthesized. The proteins of a cell determine its
structure and the functions it can perform.
When you look at the nucleus, even in an electron micrograph, you cannot see a
DNA molecule. You can see chromatin, which consists of DNA and associated
proteins. Chromatin looks grainy, but actually it is a threadlike material that
undergoes coiling to form rodlike structures, called chromosomes, just before the
cell divides. Chromatin is immersed in a semifluid medium called the
nucleoplasm. A difference in pH between the nucleoplasm and the cytoplasm
suggests that the nucleoplasm has a different composition
Most likely, too, when you look at an electron micrograph of a nucleus, you will
see one or more regions that look darker than the rest of the chromatin. These
are nucleoli (sing., nucleolus), where another type of RNA, called ribosomal RNA
(rRNA), is produced and where rRNA joins with proteins to form the subunits of
ribosomes. (Ribosomes are small bodies in the cytoplasm that contain rRNA and
proteins.)
The nucleus is separated from the cytoplasm by a double membrane known as
the nuclear envelope, which is continuous with the endoplasmic reticulum
discussed on the next page. The nuclear envelope has nuclear pores of sufficient
size (100 nm) to permit the passage of proteins into the nucleus and ribosomal
subunits out of the nucleus.
Ribosomes
Ribosomes are made up of two subunits, a large and a small one. Each subunit
has its own mix of proteins and rNA. Its shape is rounded and its size is 29
nanometers in prokaryotic cells and 32 nanometers in eukaryotes. They are the
cellular centers of translation that make
possible the expression of genes and the
synthesis of proteins in ribosomes.
Ribosomes can be found within the
cytoplasm, either individually or in groups
called polyribosomes. Ribosomes can
also be found attached to the
endoplasmic reticulum.
Chromosome
In the nucleus of each cell, the DNA molecule is packaged into thread-like
structures called chromosomes. Each chromosome is made up of DNA tightly
coiled many times around
proteins called histones that
support its structure.
Chromosomes are not
visible in the cell’s nucleus—
not even under a
microscope—when the cell
is not dividing. However, the
DNA that makes up
chromosomes becomes
more tightly packed during
cell division and is then
visible under a microscope.
Most of what researchers
know about chromosomes
was learned by observing chromosomes during cell division.
Each chromosome has a constriction point called the centromere, which divides
the chromosome into two sections, or “arms.” The short arm of the chromosome
is labeled the “p arm.” The long arm of the chromosome is labeled the “q arm.”
The location of the centromere on each chromosome gives the chromosome its
characteristic shape, and can be used to help describe the location of specific
genes.
DNA and histone proteins are packaged into structures called chromosomes.
The endoplasmic reticulum (ER), a complicated system of membranous
channels and saccules (flattened vesicles), is physically continuous with the
outer membrane of the nuclear envelope.
Rough ER is studded with ribosomes on the side of the membrane that
faces the cytoplasm
Smooth ER, which is continuous with rough ER, doesnot have attached
ribosomes. Smooth ER synthesizes the phospholipids that occur in
membranes and has various other functions depending on the particular
cell.
Mitochondria
Most mitochondria are usually 0.5–1.0 m in diameter and 2–5 m in length.
Mitochondria, like chloroplasts, are bounded by a double membrane. In
mitochondria, the inner fluidfilled space is called the matrix. The matrix contains
DNA, ribosomes, and enzymes that break down carbohydrate products, releasing
energy to be used for ATP production.
The inner membrane of a mitochondrion invaginates to form cristae. Mitochondria
and chloroplasts are able to make some proteins, but others are imported from
the cytoplasm.
The Cytoskeleton
The cytoskeleton is a network of
interconnected filaments and tubules that
extends from the nucleus to the plasma
membrane in eukaryotic cells. Prior to the
1970s, it was believed that the cytoplasm
was an unorganized mixture of organic
molecules. Then, high-voltage electron
microscopes, which can penetrate thicker
specimens, showed that the cytoplasm is
instead highly organized. It contains actin
filaments, microtubules, and intermediate
filaments. The technique of
immunofluorescence microscopy identified
the makeup of these protein fibers within the
cytoskeletal network.
The name cytoskeleton is convenient in that it compares the cytoskeleton to the
bones and muscles of an animal. Bones and muscles give an animal structure
and produce movement. Similarly, the fibers of the cytoskeleton maintain cell
shape and cause the cell and its organelles to move. The cytoskeleton is
dynamic; assembly occurs when monomers join a fiber and disassembly occurs
when monomers leave a fiber. Assembly and disassembly occur at rates that are
measured in seconds and minutes. The entire cytoskeletal network can even
disappear and reappear at various times in the life of a cell.
Microtubules
Microtubules are small, hollow
cylinders about 25 nm in
diameter and from 0.2 to 25 m in
length. Microtubules are made of
a globular protein called tubulin.
When microtubules assemble,
tubulin molecules come together
as dimers, and the dimers
arrange themselves in rows.
Microtubules have 13 rows of
tubulin dimers surrounding what
appears in electron micrographs
to be an empty central core. in
many cells, microtubule
assembly is under the control of
a microtubule organizing center,
MTCO, called the centrosome.
The centrosome lies near the
nucleus. Before a cell divides, the
microtubules assemble into a structure called a spindle that distributes
chromosomes in an orderly manner. At the end of cell division, the spindle
disassembles, and the microtubules reassemble once again into their former
array.
When the cell is not dividing, microtubules help maintain the shape of the cell and
act as tracks along which organelles can move. Motor molecules are proteins that
derive energy from ATP to propell themselves along a protein filament or
microtubule. Whereas, the motor molecule myosin is associated with actin
filaments, the motor molecules kinesin and dynein move along microtubules.
One type of kinesin is responsible for moving vesicles along microtubules,
including microtubules, including the transport vesicles of the endomembrane
system. The vesicle is bonded to the kinesin, and then kinensin “walks” along the
microtubule by attaching and reattaching itself further along the microtubule.
There are different types of kinesin proteins, each specialized to move one kind
of vesicle or cellular organelle. One type of dynein molecule, called cytoplasmic
dynein, is closely related to the dynein found in flagella
Actin Filaments
Actin filaments (formerly called
microfilaments) are long, extremely thin
fibers (about 7 nm in diameter) that
occur in bundles or meshlike networks.
The actin filament contains two chains
of globular actin monomers twisted
about one another in a helical manner.
Actin filaments play a structural role by
forming a dense complex web just under
the plasma membrane, to which they
are anchored by special proteins. Also,
the assembly and disassembly of a
network of actin filaments lying beneath
the plasma membrane accounts for the
formation of pseudopods, extensions
that allow certain cells to move in an amoeboid fashion. Actin filaments are seen
in the microvilli that Project from intestinal cells, and their presence most likely
accounts for the ability of microvilli to alternately shorten and extend into the
intestine. In plant cells, actin filaments apparently form the tracks along which
chloroplasts circulate or stream in a particular direction.
How are actin filaments involved in the movement of the cell and its organelles?
They interact with motor molecule called myosin. Myosin has both a head and a
tail. In the presence of ATP, the myosin head attaches, and then reattaches to an
actin filament at a more distant location. In muscle cells, the tails of several
muscle myosin molecules are joined to form a thick filament. In nonmuscle cells,
cytoplasmic myosin tails are bound to membranes, but the heads still interact with
actin. During animal cell division, the two new cells form when actin, in
conjunction with myosin, pinches off the cells from one another.
Intermediate Filaments
Intermediate filaments (8–11 nm in
diameter) are intermediate in size between
actin filaments and microtubules. They are
ropelike assemblies of fibrous polypeptides
that support the nuclear envelope and the
plasma membrane. In the skin, intermediate
filaments made of the protein keratin give
great mechanical strength to skin cells.
Recent work has shown intermediate
filaments to be highly dynamic. They also
are able to assemble and disassemble in
thesame manner as actin filaments and
microtubules.