-
Hedgehog Signalling Pathway
The Hedgehog signaling pathway is a signaling pathway that transmits information to embryonic cells required for proper cell differentiation. Different parts of the embryo have different concentrations of hedgehog signaling proteins.
The pathway takes its name from its polypeptide ligand, an intercellular signaling molecule called Hedgehog (Hh) found in fruit flies of the genus Drosophila; fruit fly larva lacking the Hh gene are said to resemble hedgehogs. Hh is one of Drosophila's segment polarity gene products, involved in establishing the basis of the fly body plan. Larvae without Hh, are short and spiny, resembling the hedgehog animal.
Mammals have three Hedgehog homologues, Desert (DHH), Indian (IHH), and Sonic (SHH), of which Sonic is the best studied. The pathway is equally import...
published: 03 Jul 2019
-
Hedgehog signaling pathway | Sonic Hedgehog protein Hh
Hedgehog signaling pathway or sonic Hedgehog signaling - This cell signaling lecture explains about the Hedgehog signaling pathway with the help of Hedgehog signaling pathway animation. Stay tuned to know more about the Hedgehog signaling pathway animation with the help of this animated lecture on Hedgehog signaling and the steps of Hedgehog signaling.
Hedgehog signaling pathway and the principle of Hedgehog signaling pathway is well explained with the help of this Hedgehog signaling animation lecture.
Hedgehog pathway is activated with Hedgehog protein. This Hedgehog protein act as the ligand for Hedgehog signaling pathway also known as the sonic Hedgehog signaling pathway.
What is Hedgehog signaling pathway?
What is the Hedgehog signaling receptor?
What is sonic Hedgehog?
Join, Sho...
published: 24 Aug 2022
-
Introduction to Hedgehog Signaling: Hedgehog Protein Synthesis and Release
Lesson on Hedgehog protein synthesis and cellular release. The Hedgehog signaling pathway is important in embryological development of both invertebrates and vertebrates. Hedgehog proteins are synthesized as precursor proteins and processed in several steps. Upon completion of synthesis, hedgehog proteins are released from the synthesizing cell via 4 different mechanisms.
In this lesson, you will learn about the 3 hedgehog protein homologues in mammals, how hedgehog proteins are synthesized, and you will also learn the 4 different mechanisms by which hedgehog proteins are released.
*Subscribe for more free medical lessons* https://www.youtube.com/channel/UCFPvnkCZbHfBvV8ApBBE0vA?sub_confirmation=1
-----------------------------------------------------------------------------------------...
published: 21 Jan 2018
-
Gene Music using Protein Sequence of DHH "DESERT HEDGEHOG"
Shop DHH - https://www.redbubble.com/people/genemusic/works/45060222-dhh?asc=u
Subscribe - https://www.youtube.com/c/GeneMusicStudio?sub_confirmation=1
Gene Music Studio - A channel to taste (visually & musically) gene information (particularly protein sequences)
Gene Music using Protein Sequence of DHH 'DESERT HEDGEHOG'
published: 26 Apr 2016
-
Hedgehog Signaling Pathway | Hedgehog Types | Hedgehog Pathway | Cell Signaling By Vikrant sir
Hedgehog Signaling Pathway | Hedgehog Types | Hedgehog Pathway | Cell Signaling By Vikrant sir
in this video we are providing -
Hedgehog Signaling Pathway
Hedgehog Types | Hedgehog Pathway
Cell Signaling By Vikrant sir
hedgehog pathway
sonic hedgehog Signaling Pathway
desert hedgehog Signaling Pathway
Indian hedgehog Signaling Pathway
Frizzled Receptor
Smothened Receptor
#hadgehogsignalingpathway
The Hedgehog signaling pathway is a signaling pathway that transmits information to embryonic cells required for proper cell differentiation. Different parts of the embryo have different concentrations of hedgehog signaling proteins. The pathway also has roles in the adult.
The Hedgehog signaling pathway is one of the key regulators of animal development and is present in all bilaterians.[...
published: 09 Dec 2023
-
Hedgehog Grass Go Animals Nature
#shorts
published: 09 Jul 2022
-
sonic hedgehog short video
here are 10 amazing facts about the "sonic hedgehog" gene in detail:
Discovery: The Sonic Hedgehog (SHH) gene was named after the famous video game character Sonic the Hedgehog due to its spiky appearance in fruit fly embryos, resembling the hedgehog spines.
Role in Development: SHH is a crucial player in embryonic development, influencing the formation of various body structures, including the nervous system, limbs, and facial features.
Signaling Pathway: The SHH gene encodes a protein that acts as a signaling molecule. It activates a pathway that guides cells to become specific cell types during development.
Three Versions: There are three known homologs of the SHH gene in vertebrates: Sonic Hedgehog (SHH), Indian Hedgehog (IHH), and Desert Hedgehog (DHH). Each plays distinct roles i...
published: 29 Aug 2023
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Hedgehog signaling pathway
The Hedgehog signaling pathway is a signaling pathway that transmits information to embryonic cells required for proper development. Different parts of the embryo have different concentrations of hedgehog signaling proteins. The pathway also has roles in the adult. Diseases associated with the malfunction of this pathway include basal cell carcinoma.
The Hedgehog signaling pathway is one of the key regulators of animal development and is present in all bilaterians. The pathway takes its name from its polypeptide ligand, an intercellular signaling molecule called Hedgehog found in fruit flies of the genus Drosophila. Hh is one of Drosophila's segment polarity gene products, involved in establishing the basis of the fly body plan. The molecule remains important during later stages of embryog...
published: 19 Dec 2015
-
Sonic Hedgehog Pathway Explained
Biology is full of mysterious, complex combinations of signaling pathways. One of these mysterious pathways is the Sonic Hedgehog pathway, which, despite all the unknowns, I attempt to explain in this lovely video.
published: 23 Dec 2018
-
APHMAU FRIENDS DANCE CREW | CHICKEN WINGS MEME | GANGNAM STYLE | SHUFFLE DANCE - Minecraft Animation
⚠️ DISCLAIMER TO ALL MY VIEWERS! ⚠️
Welcome to our channel! We create exciting and adventurous fictional content that may include simulated explosions, action-packed fighting scenes, fictional firearm depictions, and heartwarming romantic moments. Please keep in mind that everything you see in our videos is purely fictional and not real. Our goal is to provide family-friendly entertainment while maintaining a safe and enjoyable environment for viewers of all ages.
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"This channel is unrelated to Mojang Studios, Microsoft Corporation, or their affiliates. Our content is not endorsed by or affiliated with these companies. Any Minecraft-related trademarks are owned by their respective owners. Views expressed here are our own and do not represent Mojang Stud...
published: 25 Jan 2023
5:02
Hedgehog Signalling Pathway
The Hedgehog signaling pathway is a signaling pathway that transmits information to embryonic cells required for proper cell differentiation. Different parts of...
The Hedgehog signaling pathway is a signaling pathway that transmits information to embryonic cells required for proper cell differentiation. Different parts of the embryo have different concentrations of hedgehog signaling proteins.
The pathway takes its name from its polypeptide ligand, an intercellular signaling molecule called Hedgehog (Hh) found in fruit flies of the genus Drosophila; fruit fly larva lacking the Hh gene are said to resemble hedgehogs. Hh is one of Drosophila's segment polarity gene products, involved in establishing the basis of the fly body plan. Larvae without Hh, are short and spiny, resembling the hedgehog animal.
Mammals have three Hedgehog homologues, Desert (DHH), Indian (IHH), and Sonic (SHH), of which Sonic is the best studied. The pathway is equally important during vertebrate embryonic development and is therefore of interest in evolutionary developmental biology.
Insect cells express a full size zinc-finger transcription factor Cubitus interruptus (Ci), which forms a complex with the kinesin-like protein Costal-2 (Cos2) and is localized in the cytoplasm bound to cellular microtubules . The SCF complex targets the 155 kDa full length Ci protein for proteosome-dependent cleavage, which generates a 75 kDa fragment (CiR). CiR builds up in the cell and diffuses into the nucleus, where it acts as a co-repressor for Hedgehog (Hh) target genes.The steps leading to Ci protein proteolysis include phosphorylation of Ci protein by several protein kinases; PKA, GSK3β and CK1 .The Drosophila protein Slimb is part of an SCF complex that targets proteins for ubiquitylation. Slimb binds to phosphorylated Ci protein.
In the absence of Hh , a cell-surface transmembrane protein called Patched (PTCH) acts to prevent high expression and activity of a 7 membrane spanning receptor called Smoothened (SMO). Patched has sequence similarity to known membrane transport proteins. When extracellular Hh is present , it binds to and inhibits Patched, allowing Smoothened to accumulate and inhibit the proteolytic cleavage of the Ci protein. This process most likely involves the direct interaction of Smoothened and Costal-2 and may involve sequestration of the Ci protein-containing complex to a microdomain where the steps leading to Ci protein proteolysis are disrupted. Following binding of Hh to Patched, Smoothened levels increase greatly over the level maintained in cells when Patched is not bound to Hh. It has been suggested that phosphorylation of Smoothened plays a role in Hh-dependent regulation of Smoothened levels.
https://wn.com/Hedgehog_Signalling_Pathway
The Hedgehog signaling pathway is a signaling pathway that transmits information to embryonic cells required for proper cell differentiation. Different parts of the embryo have different concentrations of hedgehog signaling proteins.
The pathway takes its name from its polypeptide ligand, an intercellular signaling molecule called Hedgehog (Hh) found in fruit flies of the genus Drosophila; fruit fly larva lacking the Hh gene are said to resemble hedgehogs. Hh is one of Drosophila's segment polarity gene products, involved in establishing the basis of the fly body plan. Larvae without Hh, are short and spiny, resembling the hedgehog animal.
Mammals have three Hedgehog homologues, Desert (DHH), Indian (IHH), and Sonic (SHH), of which Sonic is the best studied. The pathway is equally important during vertebrate embryonic development and is therefore of interest in evolutionary developmental biology.
Insect cells express a full size zinc-finger transcription factor Cubitus interruptus (Ci), which forms a complex with the kinesin-like protein Costal-2 (Cos2) and is localized in the cytoplasm bound to cellular microtubules . The SCF complex targets the 155 kDa full length Ci protein for proteosome-dependent cleavage, which generates a 75 kDa fragment (CiR). CiR builds up in the cell and diffuses into the nucleus, where it acts as a co-repressor for Hedgehog (Hh) target genes.The steps leading to Ci protein proteolysis include phosphorylation of Ci protein by several protein kinases; PKA, GSK3β and CK1 .The Drosophila protein Slimb is part of an SCF complex that targets proteins for ubiquitylation. Slimb binds to phosphorylated Ci protein.
In the absence of Hh , a cell-surface transmembrane protein called Patched (PTCH) acts to prevent high expression and activity of a 7 membrane spanning receptor called Smoothened (SMO). Patched has sequence similarity to known membrane transport proteins. When extracellular Hh is present , it binds to and inhibits Patched, allowing Smoothened to accumulate and inhibit the proteolytic cleavage of the Ci protein. This process most likely involves the direct interaction of Smoothened and Costal-2 and may involve sequestration of the Ci protein-containing complex to a microdomain where the steps leading to Ci protein proteolysis are disrupted. Following binding of Hh to Patched, Smoothened levels increase greatly over the level maintained in cells when Patched is not bound to Hh. It has been suggested that phosphorylation of Smoothened plays a role in Hh-dependent regulation of Smoothened levels.
- published: 03 Jul 2019
- views: 44000
6:03
Hedgehog signaling pathway | Sonic Hedgehog protein Hh
Hedgehog signaling pathway or sonic Hedgehog signaling - This cell signaling lecture explains about the Hedgehog signaling pathway with the help of Hedgehog sig...
Hedgehog signaling pathway or sonic Hedgehog signaling - This cell signaling lecture explains about the Hedgehog signaling pathway with the help of Hedgehog signaling pathway animation. Stay tuned to know more about the Hedgehog signaling pathway animation with the help of this animated lecture on Hedgehog signaling and the steps of Hedgehog signaling.
Hedgehog signaling pathway and the principle of Hedgehog signaling pathway is well explained with the help of this Hedgehog signaling animation lecture.
Hedgehog pathway is activated with Hedgehog protein. This Hedgehog protein act as the ligand for Hedgehog signaling pathway also known as the sonic Hedgehog signaling pathway.
What is Hedgehog signaling pathway?
What is the Hedgehog signaling receptor?
What is sonic Hedgehog?
Join, Shomu's Biology csir net life science online coaching -
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Remember Shomu’s Biology is created to spread the knowledge of life science and biology by sharing all this free biology lectures video and animation presented by Suman Bhattacharjee in YouTube. All these tutorials are brought to you for free. Please subscribe to our channel so that we can grow together. You can check for any of the following services from Shomu’s Biology-
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Thank you for watching the cell signaling pathway lecture on Hedgehog signaling pathway.
#hedgehogsignaling #sonichedgehog
https://wn.com/Hedgehog_Signaling_Pathway_|_Sonic_Hedgehog_Protein_Hh
Hedgehog signaling pathway or sonic Hedgehog signaling - This cell signaling lecture explains about the Hedgehog signaling pathway with the help of Hedgehog signaling pathway animation. Stay tuned to know more about the Hedgehog signaling pathway animation with the help of this animated lecture on Hedgehog signaling and the steps of Hedgehog signaling.
Hedgehog signaling pathway and the principle of Hedgehog signaling pathway is well explained with the help of this Hedgehog signaling animation lecture.
Hedgehog pathway is activated with Hedgehog protein. This Hedgehog protein act as the ligand for Hedgehog signaling pathway also known as the sonic Hedgehog signaling pathway.
What is Hedgehog signaling pathway?
What is the Hedgehog signaling receptor?
What is sonic Hedgehog?
Join, Shomu's Biology csir net life science online coaching -
http://www.shomusbiology.com/net-coaching
Get Shomu's Biology CSIR NET life science study materials here-
http://www.shomusbiology.com/dvd-store/
Download the study materials here-
http://shomusbiology.com/bio-materials.html
Remember Shomu’s Biology is created to spread the knowledge of life science and biology by sharing all this free biology lectures video and animation presented by Suman Bhattacharjee in YouTube. All these tutorials are brought to you for free. Please subscribe to our channel so that we can grow together. You can check for any of the following services from Shomu’s Biology-
Buy Shomu’s Biology lecture DVD set- www.shomusbiology.com/dvd-store
Shomu’s Biology assignment services – www.shomusbiology.com/assignment -help
Join Online coaching for CSIR NET exam – www.shomusbiology.com/net-coaching
We are social. Find us on different sites here-
Our Website – www.shomusbiology.com
Facebook page- https://www.facebook.com/ShomusBiology/
Twitter - https://twitter.com/shomusbiology
SlideShare- www.slideshare.net/shomusbiology
Google plus- https://plus.google.com/113648584982732129198
LinkedIn - https://www.linkedin.com/in/suman-bhattacharjee-2a051661
Youtube- https://www.youtube.com/user/TheFunsuman
Thank you for watching the cell signaling pathway lecture on Hedgehog signaling pathway.
#hedgehogsignaling #sonichedgehog
- published: 24 Aug 2022
- views: 4949
6:38
Introduction to Hedgehog Signaling: Hedgehog Protein Synthesis and Release
Lesson on Hedgehog protein synthesis and cellular release. The Hedgehog signaling pathway is important in embryological development of both invertebrates and ve...
Lesson on Hedgehog protein synthesis and cellular release. The Hedgehog signaling pathway is important in embryological development of both invertebrates and vertebrates. Hedgehog proteins are synthesized as precursor proteins and processed in several steps. Upon completion of synthesis, hedgehog proteins are released from the synthesizing cell via 4 different mechanisms.
In this lesson, you will learn about the 3 hedgehog protein homologues in mammals, how hedgehog proteins are synthesized, and you will also learn the 4 different mechanisms by which hedgehog proteins are released.
*Subscribe for more free medical lessons* https://www.youtube.com/channel/UCFPvnkCZbHfBvV8ApBBE0vA?sub_confirmation=1
-------------------------------------------------------------------------------------------------------------
For books and more information on these topics
https://www.amazon.com/shop/jjmedicine
Support future lessons (and get other cool stuff) ➜ https://www.patreon.com/jjmedicine
Follow me on Twitter! ➜ https://twitter.com/JJ_Medicine
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Check out some of my other lessons.
Medical Terminology - The Basics - Lesson 1:
https://www.youtube.com/watch?v=04Wh2E9oNug
Fatty Acid Synthesis Pathway:
https://www.youtube.com/watch?v=WuQS_LpNMzo
Wnt/B Catenin Signaling Pathway:
https://www.youtube.com/watch?v=NGVP4J9jpgs
Upper vs. Lower Motor Neuron Lesions:
https://www.youtube.com/watch?v=itNd74V53ng
Lesson on the Purine Synthesis and Salvage Pathway:
https://www.youtube.com/watch?v=e2KFVvI8Akk
Gastrulation | Formation of Germ Layers:
https://www.youtube.com/watch?v=d6Kkn0SECJ4
Introductory lesson on Autophagy (Macroautophagy):
https://www.youtube.com/watch?v=UmSVKzHc5yA
Infectious Disease Playlist
https://www.youtube.com/playlist?list=PLRjNoiRtdFwW0Bkc6c66uDACkzotaK26b
Dermatology Playlist
https://www.youtube.com/playlist?list=PLRjNoiRtdFwW3dgORRNmk_MZvnWpZx_lW
Pharmacology Playlist
https://www.youtube.com/playlist?list=PLRjNoiRtdFwWPWcV9lZTh-Qxv0gYakQXR
Hematology Playlist
https://www.youtube.com/playlist?list=PLRjNoiRtdFwW8Ajo1dmxdj4EYEKcbtGju
Rheumatology Playlist
https://www.youtube.com/playlist?list=PLRjNoiRtdFwWDvuhasXsuTFXJp05wwUle
Endocrinology Playlist
https://www.youtube.com/playlist?list=PLRjNoiRtdFwUuRSzhploohnaWVvbVZ7ZP
Nephrology Playlist
https://www.youtube.com/playlist?list=PLRjNoiRtdFwXRSwrFQK5WwWZLk1Las8v8
----------------------------------------------------------------------------------------------------
**MEDICAL DISCLAIMER**: JJ Medicine does not provide medical advice, and the information available on this channel does not offer a diagnosis or advice regarding treatment. Information presented in these lessons is for educational purposes ONLY, and information presented here is not to be used as an alternative to a healthcare professional’s diagnosis and treatment of any person/animal.
Only a physician or other licensed healthcare professional are able to determine the requirement for medical assistance to be given to a patient. Please seek the advice of your physician or other licensed healthcare provider if you have any questions regarding a medical condition.
----------------------------------------------------------------------------------------------------
*Although I try my best to present accurate information, there may be mistakes in this video. If you do see any mistakes with information in this lesson, please comment and let me know.*
I am always looking for ways to improve my lessons! Please don't hesitate to leave me feedback and comments - all of your feedback is greatly appreciated! :) And please don't hesitate to send me any messages if you need any help - I will try my best to be here to help you guys :)
Thanks for watching! If you found this video helpful, please like and subscribe!
JJ
https://wn.com/Introduction_To_Hedgehog_Signaling_Hedgehog_Protein_Synthesis_And_Release
Lesson on Hedgehog protein synthesis and cellular release. The Hedgehog signaling pathway is important in embryological development of both invertebrates and vertebrates. Hedgehog proteins are synthesized as precursor proteins and processed in several steps. Upon completion of synthesis, hedgehog proteins are released from the synthesizing cell via 4 different mechanisms.
In this lesson, you will learn about the 3 hedgehog protein homologues in mammals, how hedgehog proteins are synthesized, and you will also learn the 4 different mechanisms by which hedgehog proteins are released.
*Subscribe for more free medical lessons* https://www.youtube.com/channel/UCFPvnkCZbHfBvV8ApBBE0vA?sub_confirmation=1
-------------------------------------------------------------------------------------------------------------
For books and more information on these topics
https://www.amazon.com/shop/jjmedicine
Support future lessons (and get other cool stuff) ➜ https://www.patreon.com/jjmedicine
Follow me on Twitter! ➜ https://twitter.com/JJ_Medicine
Come join me on Facebook! ➜ https://www.facebook.com/JJ-Medicine-100642648161192/
Start your own website with BlueHost ➜ https://www.bluehost.com/track/jjmedicine/
Check out the best tool to help grow your YouTube channel (it’s helped me!)
https://www.tubebuddy.com/jjmedicine
-------------------------------------------------------------------------------------------------------------
Check out some of my other lessons.
Medical Terminology - The Basics - Lesson 1:
https://www.youtube.com/watch?v=04Wh2E9oNug
Fatty Acid Synthesis Pathway:
https://www.youtube.com/watch?v=WuQS_LpNMzo
Wnt/B Catenin Signaling Pathway:
https://www.youtube.com/watch?v=NGVP4J9jpgs
Upper vs. Lower Motor Neuron Lesions:
https://www.youtube.com/watch?v=itNd74V53ng
Lesson on the Purine Synthesis and Salvage Pathway:
https://www.youtube.com/watch?v=e2KFVvI8Akk
Gastrulation | Formation of Germ Layers:
https://www.youtube.com/watch?v=d6Kkn0SECJ4
Introductory lesson on Autophagy (Macroautophagy):
https://www.youtube.com/watch?v=UmSVKzHc5yA
Infectious Disease Playlist
https://www.youtube.com/playlist?list=PLRjNoiRtdFwW0Bkc6c66uDACkzotaK26b
Dermatology Playlist
https://www.youtube.com/playlist?list=PLRjNoiRtdFwW3dgORRNmk_MZvnWpZx_lW
Pharmacology Playlist
https://www.youtube.com/playlist?list=PLRjNoiRtdFwWPWcV9lZTh-Qxv0gYakQXR
Hematology Playlist
https://www.youtube.com/playlist?list=PLRjNoiRtdFwW8Ajo1dmxdj4EYEKcbtGju
Rheumatology Playlist
https://www.youtube.com/playlist?list=PLRjNoiRtdFwWDvuhasXsuTFXJp05wwUle
Endocrinology Playlist
https://www.youtube.com/playlist?list=PLRjNoiRtdFwUuRSzhploohnaWVvbVZ7ZP
Nephrology Playlist
https://www.youtube.com/playlist?list=PLRjNoiRtdFwXRSwrFQK5WwWZLk1Las8v8
----------------------------------------------------------------------------------------------------
**MEDICAL DISCLAIMER**: JJ Medicine does not provide medical advice, and the information available on this channel does not offer a diagnosis or advice regarding treatment. Information presented in these lessons is for educational purposes ONLY, and information presented here is not to be used as an alternative to a healthcare professional’s diagnosis and treatment of any person/animal.
Only a physician or other licensed healthcare professional are able to determine the requirement for medical assistance to be given to a patient. Please seek the advice of your physician or other licensed healthcare provider if you have any questions regarding a medical condition.
----------------------------------------------------------------------------------------------------
*Although I try my best to present accurate information, there may be mistakes in this video. If you do see any mistakes with information in this lesson, please comment and let me know.*
I am always looking for ways to improve my lessons! Please don't hesitate to leave me feedback and comments - all of your feedback is greatly appreciated! :) And please don't hesitate to send me any messages if you need any help - I will try my best to be here to help you guys :)
Thanks for watching! If you found this video helpful, please like and subscribe!
JJ
- published: 21 Jan 2018
- views: 19977
1:41
Gene Music using Protein Sequence of DHH "DESERT HEDGEHOG"
Shop DHH - https://www.redbubble.com/people/genemusic/works/45060222-dhh?asc=u
Subscribe - https://www.youtube.com/c/GeneMusicStudio?sub_confirmation=1
Gene Mus...
Shop DHH - https://www.redbubble.com/people/genemusic/works/45060222-dhh?asc=u
Subscribe - https://www.youtube.com/c/GeneMusicStudio?sub_confirmation=1
Gene Music Studio - A channel to taste (visually & musically) gene information (particularly protein sequences)
Gene Music using Protein Sequence of DHH 'DESERT HEDGEHOG'
https://wn.com/Gene_Music_Using_Protein_Sequence_Of_Dhh_Desert_Hedgehog
Shop DHH - https://www.redbubble.com/people/genemusic/works/45060222-dhh?asc=u
Subscribe - https://www.youtube.com/c/GeneMusicStudio?sub_confirmation=1
Gene Music Studio - A channel to taste (visually & musically) gene information (particularly protein sequences)
Gene Music using Protein Sequence of DHH 'DESERT HEDGEHOG'
- published: 26 Apr 2016
- views: 41
36:57
Hedgehog Signaling Pathway | Hedgehog Types | Hedgehog Pathway | Cell Signaling By Vikrant sir
Hedgehog Signaling Pathway | Hedgehog Types | Hedgehog Pathway | Cell Signaling By Vikrant sir
in this video we are providing -
Hedgehog Signaling Pathway
Hed...
Hedgehog Signaling Pathway | Hedgehog Types | Hedgehog Pathway | Cell Signaling By Vikrant sir
in this video we are providing -
Hedgehog Signaling Pathway
Hedgehog Types | Hedgehog Pathway
Cell Signaling By Vikrant sir
hedgehog pathway
sonic hedgehog Signaling Pathway
desert hedgehog Signaling Pathway
Indian hedgehog Signaling Pathway
Frizzled Receptor
Smothened Receptor
#hadgehogsignalingpathway
The Hedgehog signaling pathway is a signaling pathway that transmits information to embryonic cells required for proper cell differentiation. Different parts of the embryo have different concentrations of hedgehog signaling proteins. The pathway also has roles in the adult.
The Hedgehog signaling pathway is one of the key regulators of animal development and is present in all bilaterians.[3] The pathway takes its name from its polypeptide ligand, an intracellular signaling molecule called Hedgehog (Hh) found in fruit flies of the genus Drosophila; fruit fly larva lacking the Hh gene are said to resemble hedgehogs. Hh is one of Drosophila's segment polarity gene products, involved in establishing the basis of the fly body plan. Larvae without Hh are short and spiny, resembling the hedgehog animal. The molecule remains important during later stages of embryogenesis and metamorphosis.
Mammals have three Hedgehog homologues, Desert (DHH), Indian (IHH), and Sonic (SHH), of which Sonic is the best studied. The pathway is equally important during vertebrate embryonic development and is therefore of interest in evolutionary developmental biology. In knockout mice lacking components of the pathway, the brain, skeleton, musculature, gastrointestinal tract and lungs fail to develop correctly. Recent studies point to the role of Hedgehog signaling in regulating adult stem cells involved in maintenance and regeneration of adult tissues. The pathway has also been implicated in the development of some cancers.[1] Drugs that specifically target Hedgehog signaling to fight this disease are being actively developed by a number of pharmaceutical companies.
In the 1970s, a fundamental problem in developmental biology was to understand how a relatively simple egg can give rise to a complex segmented body plan. In the late 1970s Christiane Nüsslein-Volhard and Eric Wieschaus isolated mutations in genes that control development of the segmented anterior-posterior body axis of the fly;[4] their "saturation mutagenesis" technique resulted in the discovery of a group of genes involved in the development of body segmentation, helping to found the field of evolutionary developmental biology.[5] In 1995, they shared the Nobel Prize with Edward B. Lewis for their work studying genetic mutations in Drosophila embryogenesis.[6]
The Drosophila hedgehog (hh) gene was identified as one of several genes important for creating the differences between the anterior and posterior parts of individual body segments. The fly hh gene was independently cloned in 1992 by the labs of Jym Mohler, Philip Beachy, Thomas B. Kornberg and Saigo Kaoru. Some hedgehog mutants result in abnormally-shaped embryos that are unusually short and stubby compared to wild type embryos. The function of the hedgehog segment polarity gene has been studied for influence on the normally polarized distribution of larval cuticular denticles as well as features on adult appendages such as legs and antennae.[7] Rather than the normal pattern of denticles, hedgehog mutant larvae tend to have "solid lawns" of denticles (Figure 1). The appearance of the stubby and "hairy" larvae inspired the name 'hedgehog
https://wn.com/Hedgehog_Signaling_Pathway_|_Hedgehog_Types_|_Hedgehog_Pathway_|_Cell_Signaling_By_Vikrant_Sir
Hedgehog Signaling Pathway | Hedgehog Types | Hedgehog Pathway | Cell Signaling By Vikrant sir
in this video we are providing -
Hedgehog Signaling Pathway
Hedgehog Types | Hedgehog Pathway
Cell Signaling By Vikrant sir
hedgehog pathway
sonic hedgehog Signaling Pathway
desert hedgehog Signaling Pathway
Indian hedgehog Signaling Pathway
Frizzled Receptor
Smothened Receptor
#hadgehogsignalingpathway
The Hedgehog signaling pathway is a signaling pathway that transmits information to embryonic cells required for proper cell differentiation. Different parts of the embryo have different concentrations of hedgehog signaling proteins. The pathway also has roles in the adult.
The Hedgehog signaling pathway is one of the key regulators of animal development and is present in all bilaterians.[3] The pathway takes its name from its polypeptide ligand, an intracellular signaling molecule called Hedgehog (Hh) found in fruit flies of the genus Drosophila; fruit fly larva lacking the Hh gene are said to resemble hedgehogs. Hh is one of Drosophila's segment polarity gene products, involved in establishing the basis of the fly body plan. Larvae without Hh are short and spiny, resembling the hedgehog animal. The molecule remains important during later stages of embryogenesis and metamorphosis.
Mammals have three Hedgehog homologues, Desert (DHH), Indian (IHH), and Sonic (SHH), of which Sonic is the best studied. The pathway is equally important during vertebrate embryonic development and is therefore of interest in evolutionary developmental biology. In knockout mice lacking components of the pathway, the brain, skeleton, musculature, gastrointestinal tract and lungs fail to develop correctly. Recent studies point to the role of Hedgehog signaling in regulating adult stem cells involved in maintenance and regeneration of adult tissues. The pathway has also been implicated in the development of some cancers.[1] Drugs that specifically target Hedgehog signaling to fight this disease are being actively developed by a number of pharmaceutical companies.
In the 1970s, a fundamental problem in developmental biology was to understand how a relatively simple egg can give rise to a complex segmented body plan. In the late 1970s Christiane Nüsslein-Volhard and Eric Wieschaus isolated mutations in genes that control development of the segmented anterior-posterior body axis of the fly;[4] their "saturation mutagenesis" technique resulted in the discovery of a group of genes involved in the development of body segmentation, helping to found the field of evolutionary developmental biology.[5] In 1995, they shared the Nobel Prize with Edward B. Lewis for their work studying genetic mutations in Drosophila embryogenesis.[6]
The Drosophila hedgehog (hh) gene was identified as one of several genes important for creating the differences between the anterior and posterior parts of individual body segments. The fly hh gene was independently cloned in 1992 by the labs of Jym Mohler, Philip Beachy, Thomas B. Kornberg and Saigo Kaoru. Some hedgehog mutants result in abnormally-shaped embryos that are unusually short and stubby compared to wild type embryos. The function of the hedgehog segment polarity gene has been studied for influence on the normally polarized distribution of larval cuticular denticles as well as features on adult appendages such as legs and antennae.[7] Rather than the normal pattern of denticles, hedgehog mutant larvae tend to have "solid lawns" of denticles (Figure 1). The appearance of the stubby and "hairy" larvae inspired the name 'hedgehog
- published: 09 Dec 2023
- views: 40
0:14
sonic hedgehog short video
here are 10 amazing facts about the "sonic hedgehog" gene in detail:
Discovery: The Sonic Hedgehog (SHH) gene was named after the famous video game character S...
here are 10 amazing facts about the "sonic hedgehog" gene in detail:
Discovery: The Sonic Hedgehog (SHH) gene was named after the famous video game character Sonic the Hedgehog due to its spiky appearance in fruit fly embryos, resembling the hedgehog spines.
Role in Development: SHH is a crucial player in embryonic development, influencing the formation of various body structures, including the nervous system, limbs, and facial features.
Signaling Pathway: The SHH gene encodes a protein that acts as a signaling molecule. It activates a pathway that guides cells to become specific cell types during development.
Three Versions: There are three known homologs of the SHH gene in vertebrates: Sonic Hedgehog (SHH), Indian Hedgehog (IHH), and Desert Hedgehog (DHH). Each plays distinct roles in different parts of the body.
Patterning: SHH establishes a concentration gradient that helps establish the anterior-posterior (head-to-tail) axis in developing embryos, aiding in proper patterning of tissues and organs.
Holoprosencephaly: Mutations in the SHH gene have been linked to a congenital disorder called holoprosencephaly, where the forebrain fails to divide properly during embryonic development.
Limbs Development: SHH is responsible for guiding the development of limbs. It is secreted from a structure called the zone of polarizing activity (ZPA) in the developing limb bud, determining digit identity and spacing.
Role in Adult Tissues: Although its role is most prominent during embryonic development, SHH also has functions in adulthood, such as tissue repair and maintenance of stem cell populations.
Cancer Connection: Aberrant activation of the SHH signaling pathway has been linked to certain types of cancers, including basal cell carcinoma and medulloblastoma.
Therapeutic Potential: The SHH signaling pathway has become a target for therapeutic interventions, especially in treating certain types of cancer and regenerating damaged tissues.
https://wn.com/Sonic_Hedgehog_Short_Video
here are 10 amazing facts about the "sonic hedgehog" gene in detail:
Discovery: The Sonic Hedgehog (SHH) gene was named after the famous video game character Sonic the Hedgehog due to its spiky appearance in fruit fly embryos, resembling the hedgehog spines.
Role in Development: SHH is a crucial player in embryonic development, influencing the formation of various body structures, including the nervous system, limbs, and facial features.
Signaling Pathway: The SHH gene encodes a protein that acts as a signaling molecule. It activates a pathway that guides cells to become specific cell types during development.
Three Versions: There are three known homologs of the SHH gene in vertebrates: Sonic Hedgehog (SHH), Indian Hedgehog (IHH), and Desert Hedgehog (DHH). Each plays distinct roles in different parts of the body.
Patterning: SHH establishes a concentration gradient that helps establish the anterior-posterior (head-to-tail) axis in developing embryos, aiding in proper patterning of tissues and organs.
Holoprosencephaly: Mutations in the SHH gene have been linked to a congenital disorder called holoprosencephaly, where the forebrain fails to divide properly during embryonic development.
Limbs Development: SHH is responsible for guiding the development of limbs. It is secreted from a structure called the zone of polarizing activity (ZPA) in the developing limb bud, determining digit identity and spacing.
Role in Adult Tissues: Although its role is most prominent during embryonic development, SHH also has functions in adulthood, such as tissue repair and maintenance of stem cell populations.
Cancer Connection: Aberrant activation of the SHH signaling pathway has been linked to certain types of cancers, including basal cell carcinoma and medulloblastoma.
Therapeutic Potential: The SHH signaling pathway has become a target for therapeutic interventions, especially in treating certain types of cancer and regenerating damaged tissues.
- published: 29 Aug 2023
- views: 40
23:15
Hedgehog signaling pathway
The Hedgehog signaling pathway is a signaling pathway that transmits information to embryonic cells required for proper development. Different parts of the embr...
The Hedgehog signaling pathway is a signaling pathway that transmits information to embryonic cells required for proper development. Different parts of the embryo have different concentrations of hedgehog signaling proteins. The pathway also has roles in the adult. Diseases associated with the malfunction of this pathway include basal cell carcinoma.
The Hedgehog signaling pathway is one of the key regulators of animal development and is present in all bilaterians. The pathway takes its name from its polypeptide ligand, an intercellular signaling molecule called Hedgehog found in fruit flies of the genus Drosophila. Hh is one of Drosophila's segment polarity gene products, involved in establishing the basis of the fly body plan. The molecule remains important during later stages of embryogenesis and metamorphosis.
This video is targeted to blind users.
Attribution:
Article text available under CC-BY-SA
Creative Commons image source in video
https://wn.com/Hedgehog_Signaling_Pathway
The Hedgehog signaling pathway is a signaling pathway that transmits information to embryonic cells required for proper development. Different parts of the embryo have different concentrations of hedgehog signaling proteins. The pathway also has roles in the adult. Diseases associated with the malfunction of this pathway include basal cell carcinoma.
The Hedgehog signaling pathway is one of the key regulators of animal development and is present in all bilaterians. The pathway takes its name from its polypeptide ligand, an intercellular signaling molecule called Hedgehog found in fruit flies of the genus Drosophila. Hh is one of Drosophila's segment polarity gene products, involved in establishing the basis of the fly body plan. The molecule remains important during later stages of embryogenesis and metamorphosis.
This video is targeted to blind users.
Attribution:
Article text available under CC-BY-SA
Creative Commons image source in video
- published: 19 Dec 2015
- views: 2853
3:41
Sonic Hedgehog Pathway Explained
Biology is full of mysterious, complex combinations of signaling pathways. One of these mysterious pathways is the Sonic Hedgehog pathway, which, despite all th...
Biology is full of mysterious, complex combinations of signaling pathways. One of these mysterious pathways is the Sonic Hedgehog pathway, which, despite all the unknowns, I attempt to explain in this lovely video.
https://wn.com/Sonic_Hedgehog_Pathway_Explained
Biology is full of mysterious, complex combinations of signaling pathways. One of these mysterious pathways is the Sonic Hedgehog pathway, which, despite all the unknowns, I attempt to explain in this lovely video.
- published: 23 Dec 2018
- views: 4928
2:16
APHMAU FRIENDS DANCE CREW | CHICKEN WINGS MEME | GANGNAM STYLE | SHUFFLE DANCE - Minecraft Animation
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Welcome to our channel! We create exciting and adventurous fictional content that may include simulated explosions, action-packed fighting scenes, fictional firearm depictions, and heartwarming romantic moments. Please keep in mind that everything you see in our videos is purely fictional and not real. Our goal is to provide family-friendly entertainment while maintaining a safe and enjoyable environment for viewers of all ages.
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"This channel is unrelated to Mojang Studios, Microsoft Corporation, or their affiliates. Our content is not endorsed by or affiliated with these companies. Any Minecraft-related trademarks are owned by their respective owners. Views expressed here are our own and do not represent Mojang Studios or Microsoft Corporation."
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#JoemCraft #MinecraftAnimation #MonsterSchool
☑JoemCraft 2022
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- published: 25 Jan 2023
- views: 2205268