'+pages+''); $('.stream > div:odd').addClass('bgr_color'); updateHeight('#history'); }); window.activateTabArea = ensure(function(tab, areas){ var parsed = false; var parts = (areas || '').split('/'); window.fsonload = $.inArray('fs', parts) >= 0; if(fsonload){ parts.splice(parts.indexOf('fs'), 1); } var replayMode = false; if($.inArray('replay', parts)>=0){ replayMode = 'replay'; } var noSoundMode = false; if($.inArray('nosound', parts)>=0){ noSoundMode = 'nosound'; } if($.inArray('ns', parts)>=0){ noSoundMode = 'ns'; } var previewMode = null; if($.inArray('p', parts)>=0){ previewMode = 'p'; } if($.inArray('preview', parts)>=0){ previewMode = 'preview'; } if($.inArray('repeat', parts)>=0){ replayMode = 'repeat'; } if($.inArray('r', parts)>=0 || $.inArray('ro', parts)>=0){ replayMode = 'r'; } if(replayMode){ parts.splice(parts.indexOf(replayMode), 1); } if(noSoundMode){ parts.splice(parts.indexOf(noSoundMode), 1); } if(previewMode){ parts.splice(parts.indexOf(previewMode), 1); } if(previewMode){ if(!parts.length){ parts = ['1-14', '999:59']; } } var area = parts[0]; if(tab == 'history' && false){ var page = parseInt(area || '1') || 1; $.ajax({ url: 'https://login.wn.com/recent/json/?pp='+history_pp+'&skip='+history_pp*(page-1), dataType: 'jsonp', success: function(response){ $ensure(function(){ renderHistory(response, page); }); } }); return true; } if(tab == 'global_history' && false){ var page = parseInt(area || '1') || 1; globalHistory.fetchStream(page, '', function(){ updateHeight('#global_history'); }); return true; } if(tab == 'my_playlists' && false){ var page = parseInt(area || '1') || 1; myPlaylists.fetchStream(page, '', function(){ updateHeight('#my_playlists'); }); return true; } if(tab == 'my_videos' && false){ var page = parseInt(area || '1') || 1; myVideos.fetchStream(page, '', function(){ updateHeight('#my_videos'); }); return true; } if(tab == 'related_sites' && areas && matchPosition(areas)){ var seconds = parsePosition(areas); scrollRelated(seconds); return false; } if(matchPosition(area) || matchAction(area)){ parts.unshift('1'); area = parts[0]; } if(tab == 'expand' && area && area.match(/\d+/)) { var num = parseInt(area); if(num < 100){ //FIX ME. 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var par = el.closest('.playlist_scrollarea'); par.scrollTop(el.offset().top-par.height()/2); } var updateVolumeState = function(){ if(noSoundMode){ if(noSoundMode == 'turn-on'){ clog("Sound is on, vsid="+vp.vsid); vp.setVolumeUnMute(); noSoundMode = false; }else{ clog("Sound is off, vsid="+vp.vsid); vp.setVolumeMute(); noSoundMode = 'turn-on'; } } } var playQueueUpdate = function(){ var playPosition = playQueue[playQueuePosition]; vp.playFromPlaylist(playPosition.video); scrollToPlaylistPosition(vp); playShouldStart = playPosition.start; playShouldStop = playPosition.stop; }; var playQueueAdvancePosition = function(){ clog("Advancing play position..."); playQueuePosition ++; while(playQueuePosition < playQueue.length && !playQueue[playQueuePosition].video){ playQueuePosition ++; } if(playQueuePosition < playQueue.length){ playQueueUpdate(); }else if(vp.getReplayCurrent()){ playQueuePosition = 0; playQueueUpdate(); vp.seekTo(playShouldStart); vp.playVideo(); }else{ vp.pauseVideo(); playShouldStop = null; playShouldStart = null; } }; function loadMoreVideos(playerId, vp, start, finish, callback){ var playlistInfo = playlists[playerId-1]; if(playlistInfo.loading >= finish) return; playlistInfo.loading = finish; $.ajax({ url: '/api/upge/cheetah-photo-search/query_videos2', dataType: 'json', data: { query: playlistInfo.query, orderby: playlistInfo.orderby, start: start, count: finish-start }, success: function(response){ var pl = vp.getPlaylist().slice(0); pl.push.apply(pl, response); vp.setPlaylist(pl); callback(); } }); } if(parts.length == 1 && matchDash(parts[0])){ var pl = vp.getActualPlaylist(); var vids = parseDash(parts[0]); parts = []; for(var i = 0; i < vids.length; i++){ playQueue.push({ 'video': pl[vids[i]-1], 'start': 0, 'stop': null }) } if(vids.length){ if(vids[vids.length-1]-1>=pl.length){ loadMoreVideos(playerId, vp, pl.length, vids[vids.length-1], function(){ if(fsonload){ activateTabArea(tab, parts[0]+'/fs'); }else{ activateTabArea(tab, parts[0]); } var pls = vp.getPlaylist(); vp.playFromPlaylist(pls[pls.length-1]); vp.playVideo(); scrollToPlaylistPosition(vp); }); return true; } } if(playQueue){ playQueueUpdate(); vp.playVideo(); parsed = true; playShouldStart = 0; } } if(previewMode){ var vids = []; var dur = 0; var pl = vp.getActualPlaylist(); area = parts[0]; if(parts.length == 1 && matchPosition(parts[0])){ vids = parseDash('1-'+pl.length); dur = parsePosition(parts[0]); parts = []; }else if(parts.length == 1 && matchDash(parts[0])){ vids = parseDash(parts[0]); dur = parsePosition("999:59"); parts = []; } if(parts.length == 2 && matchDash(parts[0]) && matchPosition(parts[1])){ vids = parseDash(parts[0]); dur = parsePosition(parts[1]); parts = []; } for(var i = 0; i < vids.length; i++){ playQueue.push({ 'video': pl[vids[i]-1], 'start': 0, 'stop': dur }) } if(playQueue){ playQueueUpdate(); vp.playVideo(); parsed = true; } } if(parts.length>1){ for(var i = 0; i < parts.length; i++){ var sel = findMatchingVideo(vp, parts[i]); if(sel){ playQueue.push({ 'video': sel, 'start': 0, 'stop': null }) } } if(playQueue){ playQueueUpdate(); vp.playVideo(); parsed = true; } }else if(area){ var sel = findMatchingVideo(vp, area); if(sel){ vp.playFromPlaylist(sel); playShouldStart = 0; parsed = true; } } if(fsonload || replayMode){ playShouldStart = 0; } if(document.location.search.match('at=|queue=')){ var opts = document.location.search.replace(/^\?/,'').split(/&/g); for(var o in opts){ if(opts[o].match(/^at=(\d+:)?(\d+:)?\d+$/)){ playShouldStart = parsePosition(opts[o].substr(3)) } if(opts[o].match(/^queue=/)){ playQueue = parseList(opts[o].substr(6)); if(playQueue){ playQueuePosition = 0; playQueueUpdate(); } } } } if(matchPosition(parts[1])){ playShouldStart = parsePosition(parts[1]); parsed = true; } if(matchAction(parts[1])){ var action = parseAction(vp, area+'/'+parts[1]); playShouldStart = action.start; playShouldStop = action.stop; parsed = true; } if(playShouldStart !== null && !playQueue.length){ playQueue.push({ video: vp.getCurrentVideo(), start: playShouldStart, stop: playShouldStop }); } if(playShouldStart != null){ setInterval(function(){ if(playShouldStop && vp.currentPlayer && vp.currentPlayer.getCurrentTime() > playShouldStop){ playShouldStop = null; if(vp.getCurrentVideo() == playQueue[playQueuePosition].video){ playQueueAdvancePosition(); }else{ playShouldStart = null; } } }, 500); vp.playerContainer.bind('videoplayer.player.statechange', function(e, state){ if(state == 'ended'){ // advance to the next video playQueueAdvancePosition(); } }); vp.playerContainer.bind('videoplayer.player.readychange', function(e, state){ if(state){ updateVolumeState(); if(playShouldStart !== null){ vp.seekTo(playShouldStart); playShouldStart = null; }else{ playShouldStop = null; // someone started other video, stop playing from playQueue } } if(fsonload) { triggerFullscreen(playerId); fsonload = false; } }); } } else if(tab.match(/^wiki\d+$/)){ if(firstTimeActivate){ load_wiki($('#'+tab), function(){ if(area){ var areaNode = $('#'+area); if(areaNode.length>0){ $('html, body').scrollTop(areaNode.offset().top + 10); return true; } } }); } } return parsed; }) window.activateTab = ensure(function(tab, area){ window.activeArea = null; if(tab == 'import_videos'){ if(area){ import_videos(area); }else{ start_import(); } return true; } if(tab == 'chat'){ update_chat_position($('.chat').eq(0)); window.activeArea = 'chat'; jQuery('.tabtrigger').offscreentabs('activateTab', 'chat'); return true; } if(tab in rev_names){ tab = rev_names[tab]; } if(tab.match(':')){ return false; } var sup = $('ul li a[id=#'+tab+']'); if(sup && sup.length>0){ window.activeArea = area; sup.first().click(); if(!window.activateTabArea(tab, area)){ window.activeArea = null; } window.activeArea = null; return true; }else{ var have_tabs = $('#playlist_menu li').length; if(tab.match(/^playlists?\d+$/)){ var to_add = +tab.substring(8).replace(/^s/,'')-have_tabs; if(to_add>0 && have_tabs){ add_more_videos(to_add); return true; } } } return false; }); window.currentPath = ensure(function(){ return window.lastHistory.replace(basepath, '').split('?')[0]; }); window.main_tab = window.main_tab || 'videos'; window.addHistory = ensure(function(path){ if(window.console && console.log) console.log("Adding to history: "+path); if(window.history && history.replaceState && document.location.hostname.match(/^(youtube\.)?(\w{2,3}\.)?wn\.com$/)){ if(path == main_tab || path == main_tab+'/' || path == '' || path == '/') { path = basepath; } else if( path.match('^'+main_tab+'/') ){ path = basepath + '/' + path.replace(main_tab+'/', '').replace('--','/'); } else { path = basepath + '/' + path.replace('--','/'); } if(document.location.search){ path += document.location.search; } if(window.lastHistory) { history.pushState(null, null, path); } else if(window.lastHistory != path){ history.replaceState(null, null, path); window.lastHistory = path; } } else{ path = path.replace('--','/'); if(path == main_tab || path == main_tab+'/' || path == '' || path == '/') { path = ''; } if(window.lastHistory != '/'+path){ window.location.hash = path? '/'+path : ''; window.lastHistory = '/'+path; } } }); $('.tabtrigger li a').live('click', ensure(function() { var tab = $(this).attr('id'); if(tab.substring(0,1) == '#'){ var name = tab.substring(1); if(name in menu_names){ name = menu_names[name][0]; } realTab = rev_names[name]; $('#'+realTab).show(); if(window.console && console.log) console.log("Triggering tab: "+name+(window.activeArea?" activeArea="+window.activeArea:'')); var path = name; if(window.activeArea){ path = path + '/' + window.activeArea; } if(tab.match(/#playlist\d+/) || tab.match(/#details\d+/)){ $('.multiple-playlists').show(); $('.related_playlist').show(); $('.longest_videos_playlist').show(); }else { $('.multiple-playlists').hide(); $('.related_playlist').hide(); $('.longest_videos_playlist').hide(); } // start the related script only when the tab is on screen showing if (tab.match(/related_sites/)) { if (mc) { mc.startCredits(); } } window.activeTab = realTab; addHistory(path); setTimeout(ensure(function(){ if(tab.match(/language--/)){ $('.tabtrigger').offscreentabs('activateTab', 'language'); } if(tab.match(/weather/)) { $('.tabtrigger').offscreentabs('activateTab', 'weather'); loadContinent(); } updateMenus(tab); updateHeight(); }), 10); } return false; })); }); -->

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  Brca1

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BRCA mutation

A BRCA mutation is a mutation in either of the BRCA1 and BRCA2 genes, which are tumor suppressor genes. Hundreds of different types of mutations in these genes have been identified, some of which have been determined to be harmful, while others have no proven impact. Harmful mutations in these genes may produce a hereditary breast-ovarian cancer syndrome in affected persons. Only 5-10% of breast cancer cases in women are attributed to BRCA1 and BRCA2 mutations (with BRCA1 mutations being slightly more common than BRCA2 mutations), but the impact on women with the gene mutation is more profound. Women with harmful mutations in either BRCA1 or BRCA2 have a risk of breast cancer that is about five times the normal risk, and a risk of ovarian cancer that is about ten to thirty times normal. The risk of breast and ovarian cancer is higher for women with a high-risk BRCA1 mutation than with a BRCA2 mutation. Having a high-risk mutation does not guarantee that the woman will develop any type of cancer, or imply that any cancer that appears was actually caused by the mutation, rather than some other factor.

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This page contains text from Wikipedia, the Free Encyclopedia - https://wn.com/BRCA_mutation

BRCA1

BRCA1 and BRCA1 (/ˌbrækəˈwʌn/) are a human gene and its protein product, respectively. The official symbol (BRCA1, italic for the gene, nonitalic for the protein) and the official name (breast cancer 1) are maintained by the HGNC. Orthologs, styled Brca1 and Brca1, are common in other mammal species.BRCA1 is a human tumor suppressor gene (to be specific, a caretaker gene), found in all humans; its protein, also called by the synonym breast cancer type 1 susceptibility protein, is responsible for repairing DNA.

BRCA1 and BRCA2 are normally expressed in the cells of breast and other tissue, where they help repair damaged DNA, or destroy cells if DNA cannot be repaired. They are involved in the repair of chromosomal damage with an important role in the error-free repair of DNA double-strand breaks. If BRCA1 or BRCA2 itself is damaged by a BRCA mutation, damaged DNA is not repaired properly, and this increases the risk for breast cancer. Thus, although the terms "breast cancer susceptibility gene" and "breast cancer susceptibility protein" (used frequently both in and outside the medical literature) sound as if they describe an oncogene, BRCA1 and BRCA2 are normal; it is their mutation that is abnormal.

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This page contains text from Wikipedia, the Free Encyclopedia - https://wn.com/BRCA1

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• 

  BRCA1 and BRCA2 Mutations & Cancer (Types of Cancer, and Who’s Most At Risk)

  REUPLOADING TO FIX VIDEO ISSUE BRCA1 and BRCA2 Mutations & Cancer (Types of Cancer, and Who’s Most At Risk) BRCA1 and BRCA2 are genes involved in DNA repair and other important functions. However, mutations in BRCA1 and BRCA2 increase the risk of different types of cancer, including breast and ovarian cancer. In this lesson, we discuss the roles of normal functioning BRCA, different patient populations most at risk, different mutations, and different types of associated cancer. I hope you find this lesson helpful. If you do, please like and subscribe for more lessons like this one! JJ **MEDICAL LEGAL DISCLAIMER**: JJ Medicine does not provide medical advice, and the information available on this channel does not offer a diagnosis or advice regarding treatment. Information presented in...

  published: 27 Jul 2022
• 

  The Role of BRCA1 in Cancer

  BRCA1 is an integral protein in the DNA repair pathway. Inherited alterations in the structure of BRCA1 cause interruption of the DNA repair process, which over time, lead to accumulation of more and more DNA damage in cells. This greatly increases the risk for cancer. Women afflicted with these inherited changes in BRCA1 face a lifetime of constant surveillance and medical intervention to fight the possibility of cancer developing. At the Peter MacCallum Cancer Centre, we are at the forefront of research into the myriad mechanisms causing cancer. We also provide the world's best cancer diagnostics, care, medical advice and management and psychological support.

  published: 29 Feb 2020
• 

  Understanding BRCA1 and BRCA2: What These Mutations Mean for Breast Cancer Risk

  How can BRCA1 and BRCA2 mutations impact breast cancer risk? Who should consider genetic testing? Can BRCA mutations influence treatment options? In this video, Dr. Jennifer Griggs explains everything you need to know about the connection between BRCA gene mutations and breast cancer. Sign up to get your personalized Yerbba Report at: www.yerbba.com Connect With Yerbba! WEBSITE: www.yerbba.com INSTAGRAM: www.instagram.com/yerbba/ FACEBOOK: www.facebook.com/yerbba.breast.cancer BLOG: https://blog.yerbba.com/ #brca #breastcancer #breastcancerawareness Disclaimer: Yerbba YouTube videos are for informational purposes only, do not constitute medical advice, and are not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your medical team, mental ...

  published: 12 Oct 2023
• 

  What is BRCA1 and BRCA2?

  Women who have no family history of breast cancer and don’t carry the BRCA1 or 2 gene mutation, have only a 12% chance of getting breast cancer in their lifetime. But, women with BRCA1 have about a 65% chance of developing it by the time they turn 70; the likelihood is a little lower for women with BRCA2 at 45%. Now that you know how important BRCA1 & BRCA2 is and how it affects your cancer risk, what exactly is it? Scottsdale Healthcare’s Gynecologic Oncologist Dr. Mike Janicek explains what BRCA1 & BRCA2 is in the video below. SUBSCRIBE FOR MORE EXPERT INFORMATION AND BREAKING BREAST CANCER NEWS http://www.youtube.com/user/drjayharness VISIT BREASTCANCERANSWERS.com FOR THE LATEST IN BREAKING BREAST CANCER NEWS http://www.breastcanceranswers.com/news SUBMIT A QUESTION http://www.b...

  published: 26 Feb 2015
• 

  Understanding BRCA Mutations and Risk

  BRCA1 and BRCA2 are breast cancer gene mutations. When a mutation occurs, the gene doesn’t function properly, DNA errors don’t get repaired, and the risk of cancer increases. A genetic counselor will review your family histories, discuss the testing process, and explain benefits as well as the risks of learning about a genetic mutation that may increase your cancer risk.

  published: 14 Apr 2017
• 

  BRCA mutation

  This breast cancer lecture explains about the brca gene (brca1 and brca2 mechanism) mutation which leads to the development of breast cancer. A BRCA mutation is a mutation in both of the genes BRCA1 and BRCA2. Detrimental mutations in these tumor suppressor genes produce a hereditary breast-ovarian melanoma syndrome in affected families. Mutations in BRCA1 and BRCA2 are distinctive, and breast cancer is relatively original, so these mutations consequently account for only five to ten percent of all breast cancer cases in women. 1000s of distinctive types of mutations in these genes have been recognized. Excessive-danger mutations, which disable an primary error-free DNA repair procedure (homology directed repair), tremendously develop the character's threat of setting up breast cancer, ov...

  published: 01 Apr 2015
• 

  We All Tested Positive for BRCA

  When Elaine’s identical twin was diagnosed with breast cancer at the age of 54, she decided to get tested for the BRCA gene. What she didn’t expect was a positive result not only herself, but for her two daughters, as well. Northwell Health is New York state’s largest healthcare provider, with 23 hospitals, 650 outpatient facilities and nearly 15,000 affiliated physicians. We’re here to set the standard of care for our communities—and make the 2 million-plus patients we treat every year not only healthier, but happier. With over 66,000 employees, we have the brainpower to dream up new possibilities, and the manpower to make them a reality. Visit https://www.northwell.edu/ Subscribe to Northwell Health’s YouTube http://bit.ly/2wPz7on or head to our channel https://www.youtube.com/northw...

  published: 23 Jul 2018
• 

  What is a BRCA Gene Mutation?

  In this video, genetic counselor Joyce Turner, MSC, CGC, explains what the BRCA1 and BRCA2 genes are and how a mutation in either gene can lead to cancer. She also discusses how genetic counseling and testing can help women make informed decisions about their health. This video can also be viewed at http://www.cdc.gov/cancer/videos/breast/BringYourBrave/Genetic_Counselor/WhatIsBRCAGeneMutation/WhatIsBRCAGeneMutation_lowRes.mp4

  published: 03 Jun 2015
• 

  BRCA gene test questioned after unnecessary surgeries

  Seven women in one family had major surgery after a widely used genetic test, taken by hundreds of thousands of people, showed a high cancer risk. One of them says she was left debilitated and unable to have more children. But, years later, the family has learned the results of that BRCA test might have been wrong. Jamie Yuccas reports. Watch "CBS This Morning" HERE: http://bit.ly/1T88yAR Download the CBS News app on iOS HERE: https://apple.co/1tRNnUy Download the CBS News app on Android HERE: https://bit.ly/1IcphuX Like "CBS This Morning" on Facebook HERE: http://on.fb.me/1LhtdvI Follow "CBS This Morning" on Twitter HERE: http://bit.ly/1Xj5W3p Follow "CBS This Morning" on Instagram HERE: http://bit.ly/1Q7NGnY Get new episodes of shows you love across devices the next day, stream local ne...

  published: 24 Dec 2019
• 

  Therapeutic Supports for Young BRCA1/BRCA2 patients | Jessica Baglieri | TEDxCarletonUniversity

  In her talk, Jessica Baglieri introduces the audience to BRCA1/BRCA2 genetic mutations, shares what it is like to receive a diagnosis for one of these mutations, and discusses the need for more mental and physical support for those who have these mutations Jessica Baglieri is currently conducting research on the lived experiences of young BRCA patients and their needs. Baglieri hopes to combine her lived experience, experience as a youth mental health worker, and her research on exploring the mental and emotional needs of young women with a BRCA1/2 diagnosis to create a system that better supports the holistic needs of young BRCA patients. This talk was given at a TEDx event using the TED conference format but independently organized by a local community. Learn more at https://www.ted.com/...

  published: 02 Mar 2023

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8:37

BRCA1 and BRCA2 Mutations & Cancer (Types of Cancer, and Who’s Most At Risk)

• Order: Reorder
• Duration: 8:37
• Uploaded Date: 27 Jul 2022
• views: 60041

REUPLOADING TO FIX VIDEO ISSUE BRCA1 and BRCA2 Mutations & Cancer (Types of Cancer, and Who’s Most At Risk) BRCA1 and BRCA2 are genes involved in DNA repair a...

REUPLOADING TO FIX VIDEO ISSUE BRCA1 and BRCA2 Mutations & Cancer (Types of Cancer, and Who’s Most At Risk) BRCA1 and BRCA2 are genes involved in DNA repair and other important functions. However, mutations in BRCA1 and BRCA2 increase the risk of different types of cancer, including breast and ovarian cancer. In this lesson, we discuss the roles of normal functioning BRCA, different patient populations most at risk, different mutations, and different types of associated cancer. I hope you find this lesson helpful. If you do, please like and subscribe for more lessons like this one! JJ **MEDICAL LEGAL DISCLAIMER**: JJ Medicine does not provide medical advice, and the information available on this channel does not offer a diagnosis or advice regarding treatment. Information presented in these lessons is for educational purposes ONLY, and information presented here is not to be used as an alternative to a healthcare professional’s diagnosis and treatment of any person/animal. Only a physician or other licensed healthcare professional are able to determine the requirement for medical assistance to be given to a patient. Please seek the advice of your physician or other licensed healthcare provider if you have any questions regarding a medical condition. *AFFILIATE DISCLAIMER: This YouTube Channel uses affiliate links and may earn a commission from associated sales. *IMAGE DISCLAIMER: The content (ex. images) used in this lesson are used in accordance with Fair Use laws and are intended for educational/teaching purposes only* *Subscribe for more free medical lessons* https://www.youtube.com/channel/UCFPvnkCZbHfBvV8ApBBE0vA?sub_confirmation=1 ------------------------------------------------------------------------------------------------------------- For books and more information on these topics https://www.amazon.com/shop/jjmedicine Support future lessons and lectures ➜ https://www.patreon.com/jjmedicine Check out the best tool to help grow your YouTube channel (it’s helped me!) https://www.tubebuddy.com/jjmedicine Follow me on Twitter! ➜ https://twitter.com/JJ_Medicine Come join me on Facebook! ➜ https://www.facebook.com/JJ-Medicine-100642648161192/ ------------------------------------------------------------------------------------------------------------ *Check Out Some of My Other Lessons* Medical Terminology - The Basics - Lesson 1: https://www.youtube.com/watch?v=04Wh2E9oNug Infectious Disease Playlist https://www.youtube.com/playlist?list=PLRjNoiRtdFwW0Bkc6c66uDACkzotaK26b Dermatology Playlist https://www.youtube.com/playlist?list=PLRjNoiRtdFwW3dgORRNmk_MZvnWpZx_lW Pharmacology Playlist https://www.youtube.com/playlist?list=PLRjNoiRtdFwWPWcV9lZTh-Qxv0gYakQXR Hematology Playlist https://www.youtube.com/playlist?list=PLRjNoiRtdFwW8Ajo1dmxdj4EYEKcbtGju Rheumatology Playlist https://www.youtube.com/playlist?list=PLRjNoiRtdFwWDvuhasXsuTFXJp05wwUle Endocrinology Playlist https://www.youtube.com/playlist?list=PLRjNoiRtdFwUuRSzhploohnaWVvbVZ7ZP Nephrology Playlist https://www.youtube.com/playlist?list=PLRjNoiRtdFwXRSwrFQK5WwWZLk1Las8v8 Fatty Acid Synthesis Pathway: https://www.youtube.com/watch?v=WuQS_LpNMzo Wnt/B Catenin Signaling Pathway: https://www.youtube.com/watch?v=NGVP4J9jpgs Upper vs. Lower Motor Neuron Lesions: https://www.youtube.com/watch?v=itNd74V53ng Lesson on the Purine Synthesis and Salvage Pathway: https://www.youtube.com/watch?v=e2KFVvI8Akk Gastrulation | Formation of Germ Layers: https://www.youtube.com/watch?v=d6Kkn0SECJ4 Introductory lesson on Autophagy (Macroautophagy): https://www.youtube.com/watch?v=UmSVKzHc5yA

https://wn.com/Brca1_And_Brca2_Mutations_Cancer_(Types_Of_Cancer,_And_Who’S_Most_At_Risk)

REUPLOADING TO FIX VIDEO ISSUE BRCA1 and BRCA2 Mutations & Cancer (Types of Cancer, and Who’s Most At Risk) BRCA1 and BRCA2 are genes involved in DNA repair and other important functions. However, mutations in BRCA1 and BRCA2 increase the risk of different types of cancer, including breast and ovarian cancer. In this lesson, we discuss the roles of normal functioning BRCA, different patient populations most at risk, different mutations, and different types of associated cancer. I hope you find this lesson helpful. If you do, please like and subscribe for more lessons like this one! JJ **MEDICAL LEGAL DISCLAIMER**: JJ Medicine does not provide medical advice, and the information available on this channel does not offer a diagnosis or advice regarding treatment. Information presented in these lessons is for educational purposes ONLY, and information presented here is not to be used as an alternative to a healthcare professional’s diagnosis and treatment of any person/animal. Only a physician or other licensed healthcare professional are able to determine the requirement for medical assistance to be given to a patient. Please seek the advice of your physician or other licensed healthcare provider if you have any questions regarding a medical condition. *AFFILIATE DISCLAIMER: This YouTube Channel uses affiliate links and may earn a commission from associated sales. *IMAGE DISCLAIMER: The content (ex. images) used in this lesson are used in accordance with Fair Use laws and are intended for educational/teaching purposes only* *Subscribe for more free medical lessons* https://www.youtube.com/channel/UCFPvnkCZbHfBvV8ApBBE0vA?sub_confirmation=1 ------------------------------------------------------------------------------------------------------------- For books and more information on these topics https://www.amazon.com/shop/jjmedicine Support future lessons and lectures ➜ https://www.patreon.com/jjmedicine Check out the best tool to help grow your YouTube channel (it’s helped me!) https://www.tubebuddy.com/jjmedicine Follow me on Twitter! ➜ https://twitter.com/JJ_Medicine Come join me on Facebook! ➜ https://www.facebook.com/JJ-Medicine-100642648161192/ ------------------------------------------------------------------------------------------------------------ *Check Out Some of My Other Lessons* Medical Terminology - The Basics - Lesson 1: https://www.youtube.com/watch?v=04Wh2E9oNug Infectious Disease Playlist https://www.youtube.com/playlist?list=PLRjNoiRtdFwW0Bkc6c66uDACkzotaK26b Dermatology Playlist https://www.youtube.com/playlist?list=PLRjNoiRtdFwW3dgORRNmk_MZvnWpZx_lW Pharmacology Playlist https://www.youtube.com/playlist?list=PLRjNoiRtdFwWPWcV9lZTh-Qxv0gYakQXR Hematology Playlist https://www.youtube.com/playlist?list=PLRjNoiRtdFwW8Ajo1dmxdj4EYEKcbtGju Rheumatology Playlist https://www.youtube.com/playlist?list=PLRjNoiRtdFwWDvuhasXsuTFXJp05wwUle Endocrinology Playlist https://www.youtube.com/playlist?list=PLRjNoiRtdFwUuRSzhploohnaWVvbVZ7ZP Nephrology Playlist https://www.youtube.com/playlist?list=PLRjNoiRtdFwXRSwrFQK5WwWZLk1Las8v8 Fatty Acid Synthesis Pathway: https://www.youtube.com/watch?v=WuQS_LpNMzo Wnt/B Catenin Signaling Pathway: https://www.youtube.com/watch?v=NGVP4J9jpgs Upper vs. Lower Motor Neuron Lesions: https://www.youtube.com/watch?v=itNd74V53ng Lesson on the Purine Synthesis and Salvage Pathway: https://www.youtube.com/watch?v=e2KFVvI8Akk Gastrulation | Formation of Germ Layers: https://www.youtube.com/watch?v=d6Kkn0SECJ4 Introductory lesson on Autophagy (Macroautophagy): https://www.youtube.com/watch?v=UmSVKzHc5yA

• published: 27 Jul 2022
• views: 60041

8:25

The Role of BRCA1 in Cancer

• Order: Reorder
• Duration: 8:25
• Uploaded Date: 29 Feb 2020
• views: 18061

BRCA1 is an integral protein in the DNA repair pathway. Inherited alterations in the structure of BRCA1 cause interruption of the DNA repair process, which over...

BRCA1 is an integral protein in the DNA repair pathway. Inherited alterations in the structure of BRCA1 cause interruption of the DNA repair process, which over time, lead to accumulation of more and more DNA damage in cells. This greatly increases the risk for cancer. Women afflicted with these inherited changes in BRCA1 face a lifetime of constant surveillance and medical intervention to fight the possibility of cancer developing. At the Peter MacCallum Cancer Centre, we are at the forefront of research into the myriad mechanisms causing cancer. We also provide the world's best cancer diagnostics, care, medical advice and management and psychological support.

https://wn.com/The_Role_Of_Brca1_In_Cancer

BRCA1 is an integral protein in the DNA repair pathway. Inherited alterations in the structure of BRCA1 cause interruption of the DNA repair process, which over time, lead to accumulation of more and more DNA damage in cells. This greatly increases the risk for cancer. Women afflicted with these inherited changes in BRCA1 face a lifetime of constant surveillance and medical intervention to fight the possibility of cancer developing. At the Peter MacCallum Cancer Centre, we are at the forefront of research into the myriad mechanisms causing cancer. We also provide the world's best cancer diagnostics, care, medical advice and management and psychological support.

• published: 29 Feb 2020
• views: 18061

10:52

Understanding BRCA1 and BRCA2: What These Mutations Mean for Breast Cancer Risk

• Order: Reorder
• Duration: 10:52
• Uploaded Date: 12 Oct 2023
• views: 6930

How can BRCA1 and BRCA2 mutations impact breast cancer risk? Who should consider genetic testing? Can BRCA mutations influence treatment options? In this video,...

How can BRCA1 and BRCA2 mutations impact breast cancer risk? Who should consider genetic testing? Can BRCA mutations influence treatment options? In this video, Dr. Jennifer Griggs explains everything you need to know about the connection between BRCA gene mutations and breast cancer. Sign up to get your personalized Yerbba Report at: www.yerbba.com Connect With Yerbba! WEBSITE: www.yerbba.com INSTAGRAM: www.instagram.com/yerbba/ FACEBOOK: www.facebook.com/yerbba.breast.cancer BLOG: https://blog.yerbba.com/ #brca #breastcancer #breastcancerawareness Disclaimer: Yerbba YouTube videos are for informational purposes only, do not constitute medical advice, and are not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your medical team, mental health professional, or other qualified health provider with any questions you may have regarding your medical condition.

https://wn.com/Understanding_Brca1_And_Brca2_What_These_Mutations_Mean_For_Breast_Cancer_Risk

How can BRCA1 and BRCA2 mutations impact breast cancer risk? Who should consider genetic testing? Can BRCA mutations influence treatment options? In this video, Dr. Jennifer Griggs explains everything you need to know about the connection between BRCA gene mutations and breast cancer. Sign up to get your personalized Yerbba Report at: www.yerbba.com Connect With Yerbba! WEBSITE: www.yerbba.com INSTAGRAM: www.instagram.com/yerbba/ FACEBOOK: www.facebook.com/yerbba.breast.cancer BLOG: https://blog.yerbba.com/ #brca #breastcancer #breastcancerawareness Disclaimer: Yerbba YouTube videos are for informational purposes only, do not constitute medical advice, and are not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your medical team, mental health professional, or other qualified health provider with any questions you may have regarding your medical condition.

• published: 12 Oct 2023
• views: 6930

2:20

What is BRCA1 and BRCA2?

• Order: Reorder
• Duration: 2:20
• Uploaded Date: 26 Feb 2015
• views: 58962

Women who have no family history of breast cancer and don’t carry the BRCA1 or 2 gene mutation, have only a 12% chance of getting breast cancer in their lifetim...

Women who have no family history of breast cancer and don’t carry the BRCA1 or 2 gene mutation, have only a 12% chance of getting breast cancer in their lifetime. But, women with BRCA1 have about a 65% chance of developing it by the time they turn 70; the likelihood is a little lower for women with BRCA2 at 45%. Now that you know how important BRCA1 & BRCA2 is and how it affects your cancer risk, what exactly is it? Scottsdale Healthcare’s Gynecologic Oncologist Dr. Mike Janicek explains what BRCA1 & BRCA2 is in the video below. SUBSCRIBE FOR MORE EXPERT INFORMATION AND BREAKING BREAST CANCER NEWS http://www.youtube.com/user/drjayharness VISIT BREASTCANCERANSWERS.com FOR THE LATEST IN BREAKING BREAST CANCER NEWS http://www.breastcanceranswers.com/news SUBMIT A QUESTION http://www.breastcanceranswers.com/ DOWNLOAD DR. HARNESS' 15 QUESTIONS TO ASK YOUR DOCTOR http://www.breastcanceranswers.com/ CONNECT WITH US! Google+: http://bit.ly/16nhEnr Facebook: https://www.facebook.com/BreastCancerAnswers Twitter: https://twitter.com/BreastCancerDr

https://wn.com/What_Is_Brca1_And_Brca2

Women who have no family history of breast cancer and don’t carry the BRCA1 or 2 gene mutation, have only a 12% chance of getting breast cancer in their lifetime. But, women with BRCA1 have about a 65% chance of developing it by the time they turn 70; the likelihood is a little lower for women with BRCA2 at 45%. Now that you know how important BRCA1 & BRCA2 is and how it affects your cancer risk, what exactly is it? Scottsdale Healthcare’s Gynecologic Oncologist Dr. Mike Janicek explains what BRCA1 & BRCA2 is in the video below. SUBSCRIBE FOR MORE EXPERT INFORMATION AND BREAKING BREAST CANCER NEWS http://www.youtube.com/user/drjayharness VISIT BREASTCANCERANSWERS.com FOR THE LATEST IN BREAKING BREAST CANCER NEWS http://www.breastcanceranswers.com/news SUBMIT A QUESTION http://www.breastcanceranswers.com/ DOWNLOAD DR. HARNESS' 15 QUESTIONS TO ASK YOUR DOCTOR http://www.breastcanceranswers.com/ CONNECT WITH US! Google+: http://bit.ly/16nhEnr Facebook: https://www.facebook.com/BreastCancerAnswers Twitter: https://twitter.com/BreastCancerDr

• published: 26 Feb 2015
• views: 58962

3:52

Understanding BRCA Mutations and Risk

• Order: Reorder
• Duration: 3:52
• Uploaded Date: 14 Apr 2017
• views: 33935

BRCA1 and BRCA2 are breast cancer gene mutations. When a mutation occurs, the gene doesn’t function properly, DNA errors don’t get repaired, and the risk of can...

BRCA1 and BRCA2 are breast cancer gene mutations. When a mutation occurs, the gene doesn’t function properly, DNA errors don’t get repaired, and the risk of cancer increases. A genetic counselor will review your family histories, discuss the testing process, and explain benefits as well as the risks of learning about a genetic mutation that may increase your cancer risk.

https://wn.com/Understanding_Brca_Mutations_And_Risk

BRCA1 and BRCA2 are breast cancer gene mutations. When a mutation occurs, the gene doesn’t function properly, DNA errors don’t get repaired, and the risk of cancer increases. A genetic counselor will review your family histories, discuss the testing process, and explain benefits as well as the risks of learning about a genetic mutation that may increase your cancer risk.

• published: 14 Apr 2017
• views: 33935

17:32

BRCA mutation

• Order: Reorder
• Duration: 17:32
• Uploaded Date: 01 Apr 2015
• views: 68336

This breast cancer lecture explains about the brca gene (brca1 and brca2 mechanism) mutation which leads to the development of breast cancer. A BRCA mutation is...

This breast cancer lecture explains about the brca gene (brca1 and brca2 mechanism) mutation which leads to the development of breast cancer. A BRCA mutation is a mutation in both of the genes BRCA1 and BRCA2. Detrimental mutations in these tumor suppressor genes produce a hereditary breast-ovarian melanoma syndrome in affected families. Mutations in BRCA1 and BRCA2 are distinctive, and breast cancer is relatively original, so these mutations consequently account for only five to ten percent of all breast cancer cases in women. 1000s of distinctive types of mutations in these genes have been recognized. Excessive-danger mutations, which disable an primary error-free DNA repair procedure (homology directed repair), tremendously develop the character's threat of setting up breast cancer, ovarian melanoma and specific different cancers. Why BRCA1 and BRCA2 mutations lead preferentially to cancers of the breast and ovary is not identified, but lack of BRCA1 function seems to result in non-useful x-chromosome inactivation. No longer all mutations are excessive-chance; some show up to be harmless editions. The cancer hazard related to any given mutation varies greatly and depends on the distinctive variety and area of the mutation and in all probability different person reasons. Ladies with unsafe mutations in either BRCA1 or BRCA2 have risk of breast melanoma that is about five occasions the average chance, and a hazard of ovarian cancer that's about ten to thirty occasions common. BRCA1 mutations typically confer a higher danger of breast and ovarian melanoma in females than BRCA2 mutations. Having a high-threat mutation does no longer guarantee that the girl will increase any sort of cancer, or warranty that any melanoma that appears was once genuinely induced through the mutation, alternatively than every other element, like alcohol consumption. For more information, log on to- http://www.shomusbiology.com/ Get Shomu's Biology DVD set here- http://www.shomusbiology.com/dvd-store/ Download the study materials here- http://shomusbiology.com/bio-materials.html Remember Shomu’s Biology is created to spread the knowledge of life science and biology by sharing all this free biology lectures video and animation presented by Suman Bhattacharjee in YouTube. All these tutorials are brought to you for free. Please subscribe to our channel so that we can grow together. You can check for any of the following services from Shomu’s Biology- Buy Shomu’s Biology lecture DVD set- www.shomusbiology.com/dvd-store Shomu’s Biology assignment services – www.shomusbiology.com/assignment -help Join Online coaching for CSIR NET exam – www.shomusbiology.com/net-coaching We are social. Find us on different sites here- Our Website – www.shomusbiology.com Facebook page- https://www.facebook.com/ShomusBiology/ Twitter - https://twitter.com/shomusbiology SlideShare- www.slideshare.net/shomusbiology Google plus- https://plus.google.com/113648584982732129198 LinkedIn - https://www.linkedin.com/in/suman-bhattacharjee-2a051661 Youtube- https://www.youtube.com/user/TheFunsuman Thank you for watching

https://wn.com/Brca_Mutation

This breast cancer lecture explains about the brca gene (brca1 and brca2 mechanism) mutation which leads to the development of breast cancer. A BRCA mutation is a mutation in both of the genes BRCA1 and BRCA2. Detrimental mutations in these tumor suppressor genes produce a hereditary breast-ovarian melanoma syndrome in affected families. Mutations in BRCA1 and BRCA2 are distinctive, and breast cancer is relatively original, so these mutations consequently account for only five to ten percent of all breast cancer cases in women. 1000s of distinctive types of mutations in these genes have been recognized. Excessive-danger mutations, which disable an primary error-free DNA repair procedure (homology directed repair), tremendously develop the character's threat of setting up breast cancer, ovarian melanoma and specific different cancers. Why BRCA1 and BRCA2 mutations lead preferentially to cancers of the breast and ovary is not identified, but lack of BRCA1 function seems to result in non-useful x-chromosome inactivation. No longer all mutations are excessive-chance; some show up to be harmless editions. The cancer hazard related to any given mutation varies greatly and depends on the distinctive variety and area of the mutation and in all probability different person reasons. Ladies with unsafe mutations in either BRCA1 or BRCA2 have risk of breast melanoma that is about five occasions the average chance, and a hazard of ovarian cancer that's about ten to thirty occasions common. BRCA1 mutations typically confer a higher danger of breast and ovarian melanoma in females than BRCA2 mutations. Having a high-threat mutation does no longer guarantee that the girl will increase any sort of cancer, or warranty that any melanoma that appears was once genuinely induced through the mutation, alternatively than every other element, like alcohol consumption. For more information, log on to- http://www.shomusbiology.com/ Get Shomu's Biology DVD set here- http://www.shomusbiology.com/dvd-store/ Download the study materials here- http://shomusbiology.com/bio-materials.html Remember Shomu’s Biology is created to spread the knowledge of life science and biology by sharing all this free biology lectures video and animation presented by Suman Bhattacharjee in YouTube. All these tutorials are brought to you for free. Please subscribe to our channel so that we can grow together. You can check for any of the following services from Shomu’s Biology- Buy Shomu’s Biology lecture DVD set- www.shomusbiology.com/dvd-store Shomu’s Biology assignment services – www.shomusbiology.com/assignment -help Join Online coaching for CSIR NET exam – www.shomusbiology.com/net-coaching We are social. Find us on different sites here- Our Website – www.shomusbiology.com Facebook page- https://www.facebook.com/ShomusBiology/ Twitter - https://twitter.com/shomusbiology SlideShare- www.slideshare.net/shomusbiology Google plus- https://plus.google.com/113648584982732129198 LinkedIn - https://www.linkedin.com/in/suman-bhattacharjee-2a051661 Youtube- https://www.youtube.com/user/TheFunsuman Thank you for watching

• published: 01 Apr 2015
• views: 68336

3:11

We All Tested Positive for BRCA

• Order: Reorder
• Duration: 3:11
• Uploaded Date: 23 Jul 2018
• views: 8946

When Elaine’s identical twin was diagnosed with breast cancer at the age of 54, she decided to get tested for the BRCA gene. What she didn’t expect was a positi...

When Elaine’s identical twin was diagnosed with breast cancer at the age of 54, she decided to get tested for the BRCA gene. What she didn’t expect was a positive result not only herself, but for her two daughters, as well. Northwell Health is New York state’s largest healthcare provider, with 23 hospitals, 650 outpatient facilities and nearly 15,000 affiliated physicians. We’re here to set the standard of care for our communities—and make the 2 million-plus patients we treat every year not only healthier, but happier. With over 66,000 employees, we have the brainpower to dream up new possibilities, and the manpower to make them a reality. Visit https://www.northwell.edu/ Subscribe to Northwell Health’s YouTube http://bit.ly/2wPz7on or head to our channel https://www.youtube.com/northwellhealth1 The Well - https://thewell.northwell.edu/ Facebook – http://www.facebook.com/northwellhealth Twitter - http://www.twitter.com/northwellhealth Instagram - http://www.instagram.com/northwellhealth LinkedIn - http://www.linkedin/northwellhealth

https://wn.com/We_All_Tested_Positive_For_Brca

When Elaine’s identical twin was diagnosed with breast cancer at the age of 54, she decided to get tested for the BRCA gene. What she didn’t expect was a positive result not only herself, but for her two daughters, as well. Northwell Health is New York state’s largest healthcare provider, with 23 hospitals, 650 outpatient facilities and nearly 15,000 affiliated physicians. We’re here to set the standard of care for our communities—and make the 2 million-plus patients we treat every year not only healthier, but happier. With over 66,000 employees, we have the brainpower to dream up new possibilities, and the manpower to make them a reality. Visit https://www.northwell.edu/ Subscribe to Northwell Health’s YouTube http://bit.ly/2wPz7on or head to our channel https://www.youtube.com/northwellhealth1 The Well - https://thewell.northwell.edu/ Facebook – http://www.facebook.com/northwellhealth Twitter - http://www.twitter.com/northwellhealth Instagram - http://www.instagram.com/northwellhealth LinkedIn - http://www.linkedin/northwellhealth

• published: 23 Jul 2018
• views: 8946

1:28

What is a BRCA Gene Mutation?

• Order: Reorder
• Duration: 1:28
• Uploaded Date: 03 Jun 2015
• views: 24314

In this video, genetic counselor Joyce Turner, MSC, CGC, explains what the BRCA1 and BRCA2 genes are and how a mutation in either gene can lead to cancer. She ...

In this video, genetic counselor Joyce Turner, MSC, CGC, explains what the BRCA1 and BRCA2 genes are and how a mutation in either gene can lead to cancer. She also discusses how genetic counseling and testing can help women make informed decisions about their health. This video can also be viewed at http://www.cdc.gov/cancer/videos/breast/BringYourBrave/Genetic_Counselor/WhatIsBRCAGeneMutation/WhatIsBRCAGeneMutation_lowRes.mp4

https://wn.com/What_Is_A_Brca_Gene_Mutation

In this video, genetic counselor Joyce Turner, MSC, CGC, explains what the BRCA1 and BRCA2 genes are and how a mutation in either gene can lead to cancer. She also discusses how genetic counseling and testing can help women make informed decisions about their health. This video can also be viewed at http://www.cdc.gov/cancer/videos/breast/BringYourBrave/Genetic_Counselor/WhatIsBRCAGeneMutation/WhatIsBRCAGeneMutation_lowRes.mp4

• published: 03 Jun 2015
• views: 24314

3:50

BRCA gene test questioned after unnecessary surgeries

• Order: Reorder
• Duration: 3:50
• Uploaded Date: 24 Dec 2019
• views: 6526

Seven women in one family had major surgery after a widely used genetic test, taken by hundreds of thousands of people, showed a high cancer risk. One of them s...

Seven women in one family had major surgery after a widely used genetic test, taken by hundreds of thousands of people, showed a high cancer risk. One of them says she was left debilitated and unable to have more children. But, years later, the family has learned the results of that BRCA test might have been wrong. Jamie Yuccas reports. Watch "CBS This Morning" HERE: http://bit.ly/1T88yAR Download the CBS News app on iOS HERE: https://apple.co/1tRNnUy Download the CBS News app on Android HERE: https://bit.ly/1IcphuX Like "CBS This Morning" on Facebook HERE: http://on.fb.me/1LhtdvI Follow "CBS This Morning" on Twitter HERE: http://bit.ly/1Xj5W3p Follow "CBS This Morning" on Instagram HERE: http://bit.ly/1Q7NGnY Get new episodes of shows you love across devices the next day, stream local news live, and watch full seasons of CBS fan favorites anytime, anywhere with CBS All Access. Try it free! http://bit.ly/1OQA29B Each weekday morning, "CBS This Morning" co-hosts Gayle King, Anthony Mason and Tony Dokoupil deliver two hours of original reporting, breaking news and top-level newsmaker interviews in an engaging and informative format that challenges the norm in network morning news programs. The broadcast has earned a prestigious Peabody Award, a Polk Award, four News & Documentary Emmys, three Daytime Emmys and the 2017 Edward R. Murrow Award for Best Newscast. The broadcast was also honored with an Alfred I. duPont-Columbia Award as part of CBS News division-wide coverage of the shootings at Sandy Hook Elementary School in Newtown, Connecticut. Check local listings for "CBS This Morning" broadcast times.

https://wn.com/Brca_Gene_Test_Questioned_After_Unnecessary_Surgeries

Seven women in one family had major surgery after a widely used genetic test, taken by hundreds of thousands of people, showed a high cancer risk. One of them says she was left debilitated and unable to have more children. But, years later, the family has learned the results of that BRCA test might have been wrong. Jamie Yuccas reports. Watch "CBS This Morning" HERE: http://bit.ly/1T88yAR Download the CBS News app on iOS HERE: https://apple.co/1tRNnUy Download the CBS News app on Android HERE: https://bit.ly/1IcphuX Like "CBS This Morning" on Facebook HERE: http://on.fb.me/1LhtdvI Follow "CBS This Morning" on Twitter HERE: http://bit.ly/1Xj5W3p Follow "CBS This Morning" on Instagram HERE: http://bit.ly/1Q7NGnY Get new episodes of shows you love across devices the next day, stream local news live, and watch full seasons of CBS fan favorites anytime, anywhere with CBS All Access. Try it free! http://bit.ly/1OQA29B Each weekday morning, "CBS This Morning" co-hosts Gayle King, Anthony Mason and Tony Dokoupil deliver two hours of original reporting, breaking news and top-level newsmaker interviews in an engaging and informative format that challenges the norm in network morning news programs. The broadcast has earned a prestigious Peabody Award, a Polk Award, four News & Documentary Emmys, three Daytime Emmys and the 2017 Edward R. Murrow Award for Best Newscast. The broadcast was also honored with an Alfred I. duPont-Columbia Award as part of CBS News division-wide coverage of the shootings at Sandy Hook Elementary School in Newtown, Connecticut. Check local listings for "CBS This Morning" broadcast times.

• published: 24 Dec 2019
• views: 6526

9:46

Therapeutic Supports for Young BRCA1/BRCA2 patients | Jessica Baglieri | TEDxCarletonUniversity

• Order: Reorder
• Duration: 9:46
• Uploaded Date: 02 Mar 2023
• views: 389

In her talk, Jessica Baglieri introduces the audience to BRCA1/BRCA2 genetic mutations, shares what it is like to receive a diagnosis for one of these mutations...

In her talk, Jessica Baglieri introduces the audience to BRCA1/BRCA2 genetic mutations, shares what it is like to receive a diagnosis for one of these mutations, and discusses the need for more mental and physical support for those who have these mutations Jessica Baglieri is currently conducting research on the lived experiences of young BRCA patients and their needs. Baglieri hopes to combine her lived experience, experience as a youth mental health worker, and her research on exploring the mental and emotional needs of young women with a BRCA1/2 diagnosis to create a system that better supports the holistic needs of young BRCA patients. This talk was given at a TEDx event using the TED conference format but independently organized by a local community. Learn more at https://www.ted.com/tedx

https://wn.com/Therapeutic_Supports_For_Young_Brca1_Brca2_Patients_|_Jessica_Baglieri_|_Tedxcarletonuniversity

In her talk, Jessica Baglieri introduces the audience to BRCA1/BRCA2 genetic mutations, shares what it is like to receive a diagnosis for one of these mutations, and discusses the need for more mental and physical support for those who have these mutations Jessica Baglieri is currently conducting research on the lived experiences of young BRCA patients and their needs. Baglieri hopes to combine her lived experience, experience as a youth mental health worker, and her research on exploring the mental and emotional needs of young women with a BRCA1/2 diagnosis to create a system that better supports the holistic needs of young BRCA patients. This talk was given at a TEDx event using the TED conference format but independently organized by a local community. Learn more at https://www.ted.com/tedx

• published: 02 Mar 2023
• views: 389

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8:37

BRCA1 and BRCA2 Mutations & Cancer (Types of Cancer, and Who’s Most At Risk)

REUPLOADING TO FIX VIDEO ISSUE BRCA1 and BRCA2 Mutations & Cancer (Types of Cancer, and W...

published: 27 Jul 2022

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BRCA1 and BRCA2 Mutations & Cancer (Types of Cancer, and Who’s Most At Risk)

BRCA1 and BRCA2 Mutations & Cancer (Types of Cancer, and Who’s Most At Risk)

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• published: 27 Jul 2022
• views: 60041

REUPLOADING TO FIX VIDEO ISSUE BRCA1 and BRCA2 Mutations & Cancer (Types of Cancer, and Who’s Most At Risk) BRCA1 and BRCA2 are genes involved in DNA repair and other important functions. However, mutations in BRCA1 and BRCA2 increase the risk of different types of cancer, including breast and ovarian cancer. In this lesson, we discuss the roles of normal functioning BRCA, different patient populations most at risk, different mutations, and different types of associated cancer. I hope you find this lesson helpful. If you do, please like and subscribe for more lessons like this one! JJ **MEDICAL LEGAL DISCLAIMER**: JJ Medicine does not provide medical advice, and the information available on this channel does not offer a diagnosis or advice regarding treatment. Information presented in these lessons is for educational purposes ONLY, and information presented here is not to be used as an alternative to a healthcare professional’s diagnosis and treatment of any person/animal. Only a physician or other licensed healthcare professional are able to determine the requirement for medical assistance to be given to a patient. Please seek the advice of your physician or other licensed healthcare provider if you have any questions regarding a medical condition. *AFFILIATE DISCLAIMER: This YouTube Channel uses affiliate links and may earn a commission from associated sales. *IMAGE DISCLAIMER: The content (ex. images) used in this lesson are used in accordance with Fair Use laws and are intended for educational/teaching purposes only* *Subscribe for more free medical lessons* https://www.youtube.com/channel/UCFPvnkCZbHfBvV8ApBBE0vA?sub_confirmation=1 ------------------------------------------------------------------------------------------------------------- For books and more information on these topics https://www.amazon.com/shop/jjmedicine Support future lessons and lectures ➜ https://www.patreon.com/jjmedicine Check out the best tool to help grow your YouTube channel (it’s helped me!) https://www.tubebuddy.com/jjmedicine Follow me on Twitter! ➜ https://twitter.com/JJ_Medicine Come join me on Facebook! ➜ https://www.facebook.com/JJ-Medicine-100642648161192/ ------------------------------------------------------------------------------------------------------------ *Check Out Some of My Other Lessons* Medical Terminology - The Basics - Lesson 1: https://www.youtube.com/watch?v=04Wh2E9oNug Infectious Disease Playlist https://www.youtube.com/playlist?list=PLRjNoiRtdFwW0Bkc6c66uDACkzotaK26b Dermatology Playlist https://www.youtube.com/playlist?list=PLRjNoiRtdFwW3dgORRNmk_MZvnWpZx_lW Pharmacology Playlist https://www.youtube.com/playlist?list=PLRjNoiRtdFwWPWcV9lZTh-Qxv0gYakQXR Hematology Playlist https://www.youtube.com/playlist?list=PLRjNoiRtdFwW8Ajo1dmxdj4EYEKcbtGju Rheumatology Playlist https://www.youtube.com/playlist?list=PLRjNoiRtdFwWDvuhasXsuTFXJp05wwUle Endocrinology Playlist https://www.youtube.com/playlist?list=PLRjNoiRtdFwUuRSzhploohnaWVvbVZ7ZP Nephrology Playlist https://www.youtube.com/playlist?list=PLRjNoiRtdFwXRSwrFQK5WwWZLk1Las8v8 Fatty Acid Synthesis Pathway: https://www.youtube.com/watch?v=WuQS_LpNMzo Wnt/B Catenin Signaling Pathway: https://www.youtube.com/watch?v=NGVP4J9jpgs Upper vs. Lower Motor Neuron Lesions: https://www.youtube.com/watch?v=itNd74V53ng Lesson on the Purine Synthesis and Salvage Pathway: https://www.youtube.com/watch?v=e2KFVvI8Akk Gastrulation | Formation of Germ Layers: https://www.youtube.com/watch?v=d6Kkn0SECJ4 Introductory lesson on Autophagy (Macroautophagy): https://www.youtube.com/watch?v=UmSVKzHc5yA

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8:25

The Role of BRCA1 in Cancer

BRCA1 is an integral protein in the DNA repair pathway. Inherited alterations in the struc...

published: 29 Feb 2020

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The Role of BRCA1 in Cancer

The Role of BRCA1 in Cancer

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• published: 29 Feb 2020
• views: 18061

BRCA1 is an integral protein in the DNA repair pathway. Inherited alterations in the structure of BRCA1 cause interruption of the DNA repair process, which over time, lead to accumulation of more and more DNA damage in cells. This greatly increases the risk for cancer. Women afflicted with these inherited changes in BRCA1 face a lifetime of constant surveillance and medical intervention to fight the possibility of cancer developing. At the Peter MacCallum Cancer Centre, we are at the forefront of research into the myriad mechanisms causing cancer. We also provide the world's best cancer diagnostics, care, medical advice and management and psychological support.

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10:52

Understanding BRCA1 and BRCA2: What These Mutations Mean for Breast Cancer Risk

How can BRCA1 and BRCA2 mutations impact breast cancer risk? Who should consider genetic t...

published: 12 Oct 2023

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Understanding BRCA1 and BRCA2: What These Mutations Mean for Breast Cancer Risk

Understanding BRCA1 and BRCA2: What These Mutations Mean for Breast Cancer Risk

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• published: 12 Oct 2023
• views: 6930

How can BRCA1 and BRCA2 mutations impact breast cancer risk? Who should consider genetic testing? Can BRCA mutations influence treatment options? In this video, Dr. Jennifer Griggs explains everything you need to know about the connection between BRCA gene mutations and breast cancer. Sign up to get your personalized Yerbba Report at: www.yerbba.com Connect With Yerbba! WEBSITE: www.yerbba.com INSTAGRAM: www.instagram.com/yerbba/ FACEBOOK: www.facebook.com/yerbba.breast.cancer BLOG: https://blog.yerbba.com/ #brca #breastcancer #breastcancerawareness Disclaimer: Yerbba YouTube videos are for informational purposes only, do not constitute medical advice, and are not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your medical team, mental health professional, or other qualified health provider with any questions you may have regarding your medical condition.

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2:20

What is BRCA1 and BRCA2?

Women who have no family history of breast cancer and don’t carry the BRCA1 or 2 gene muta...

published: 26 Feb 2015

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What is BRCA1 and BRCA2?

What is BRCA1 and BRCA2?

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• published: 26 Feb 2015
• views: 58962

Women who have no family history of breast cancer and don’t carry the BRCA1 or 2 gene mutation, have only a 12% chance of getting breast cancer in their lifetime. But, women with BRCA1 have about a 65% chance of developing it by the time they turn 70; the likelihood is a little lower for women with BRCA2 at 45%. Now that you know how important BRCA1 & BRCA2 is and how it affects your cancer risk, what exactly is it? Scottsdale Healthcare’s Gynecologic Oncologist Dr. Mike Janicek explains what BRCA1 & BRCA2 is in the video below. SUBSCRIBE FOR MORE EXPERT INFORMATION AND BREAKING BREAST CANCER NEWS http://www.youtube.com/user/drjayharness VISIT BREASTCANCERANSWERS.com FOR THE LATEST IN BREAKING BREAST CANCER NEWS http://www.breastcanceranswers.com/news SUBMIT A QUESTION http://www.breastcanceranswers.com/ DOWNLOAD DR. HARNESS' 15 QUESTIONS TO ASK YOUR DOCTOR http://www.breastcanceranswers.com/ CONNECT WITH US! Google+: http://bit.ly/16nhEnr Facebook: https://www.facebook.com/BreastCancerAnswers Twitter: https://twitter.com/BreastCancerDr

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3:52

Understanding BRCA Mutations and Risk

BRCA1 and BRCA2 are breast cancer gene mutations. When a mutation occurs, the gene doesn’t...

published: 14 Apr 2017

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Understanding BRCA Mutations and Risk

Understanding BRCA Mutations and Risk

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• published: 14 Apr 2017
• views: 33935

BRCA1 and BRCA2 are breast cancer gene mutations. When a mutation occurs, the gene doesn’t function properly, DNA errors don’t get repaired, and the risk of cancer increases. A genetic counselor will review your family histories, discuss the testing process, and explain benefits as well as the risks of learning about a genetic mutation that may increase your cancer risk.

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17:32

BRCA mutation

This breast cancer lecture explains about the brca gene (brca1 and brca2 mechanism) mutati...

published: 01 Apr 2015

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BRCA mutation

BRCA mutation

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• published: 01 Apr 2015
• views: 68336

This breast cancer lecture explains about the brca gene (brca1 and brca2 mechanism) mutation which leads to the development of breast cancer. A BRCA mutation is a mutation in both of the genes BRCA1 and BRCA2. Detrimental mutations in these tumor suppressor genes produce a hereditary breast-ovarian melanoma syndrome in affected families. Mutations in BRCA1 and BRCA2 are distinctive, and breast cancer is relatively original, so these mutations consequently account for only five to ten percent of all breast cancer cases in women. 1000s of distinctive types of mutations in these genes have been recognized. Excessive-danger mutations, which disable an primary error-free DNA repair procedure (homology directed repair), tremendously develop the character's threat of setting up breast cancer, ovarian melanoma and specific different cancers. Why BRCA1 and BRCA2 mutations lead preferentially to cancers of the breast and ovary is not identified, but lack of BRCA1 function seems to result in non-useful x-chromosome inactivation. No longer all mutations are excessive-chance; some show up to be harmless editions. The cancer hazard related to any given mutation varies greatly and depends on the distinctive variety and area of the mutation and in all probability different person reasons. Ladies with unsafe mutations in either BRCA1 or BRCA2 have risk of breast melanoma that is about five occasions the average chance, and a hazard of ovarian cancer that's about ten to thirty occasions common. BRCA1 mutations typically confer a higher danger of breast and ovarian melanoma in females than BRCA2 mutations. Having a high-threat mutation does no longer guarantee that the girl will increase any sort of cancer, or warranty that any melanoma that appears was once genuinely induced through the mutation, alternatively than every other element, like alcohol consumption. For more information, log on to- http://www.shomusbiology.com/ Get Shomu's Biology DVD set here- http://www.shomusbiology.com/dvd-store/ Download the study materials here- http://shomusbiology.com/bio-materials.html Remember Shomu’s Biology is created to spread the knowledge of life science and biology by sharing all this free biology lectures video and animation presented by Suman Bhattacharjee in YouTube. All these tutorials are brought to you for free. Please subscribe to our channel so that we can grow together. You can check for any of the following services from Shomu’s Biology- Buy Shomu’s Biology lecture DVD set- www.shomusbiology.com/dvd-store Shomu’s Biology assignment services – www.shomusbiology.com/assignment -help Join Online coaching for CSIR NET exam – www.shomusbiology.com/net-coaching We are social. Find us on different sites here- Our Website – www.shomusbiology.com Facebook page- https://www.facebook.com/ShomusBiology/ Twitter - https://twitter.com/shomusbiology SlideShare- www.slideshare.net/shomusbiology Google plus- https://plus.google.com/113648584982732129198 LinkedIn - https://www.linkedin.com/in/suman-bhattacharjee-2a051661 Youtube- https://www.youtube.com/user/TheFunsuman Thank you for watching

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3:11

We All Tested Positive for BRCA

When Elaine’s identical twin was diagnosed with breast cancer at the age of 54, she decide...

published: 23 Jul 2018

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We All Tested Positive for BRCA

We All Tested Positive for BRCA

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• published: 23 Jul 2018
• views: 8946

When Elaine’s identical twin was diagnosed with breast cancer at the age of 54, she decided to get tested for the BRCA gene. What she didn’t expect was a positive result not only herself, but for her two daughters, as well. Northwell Health is New York state’s largest healthcare provider, with 23 hospitals, 650 outpatient facilities and nearly 15,000 affiliated physicians. We’re here to set the standard of care for our communities—and make the 2 million-plus patients we treat every year not only healthier, but happier. With over 66,000 employees, we have the brainpower to dream up new possibilities, and the manpower to make them a reality. Visit https://www.northwell.edu/ Subscribe to Northwell Health’s YouTube http://bit.ly/2wPz7on or head to our channel https://www.youtube.com/northwellhealth1 The Well - https://thewell.northwell.edu/ Facebook – http://www.facebook.com/northwellhealth Twitter - http://www.twitter.com/northwellhealth Instagram - http://www.instagram.com/northwellhealth LinkedIn - http://www.linkedin/northwellhealth

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1:28

What is a BRCA Gene Mutation?

In this video, genetic counselor Joyce Turner, MSC, CGC, explains what the BRCA1 and BRCA2...

published: 03 Jun 2015

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What is a BRCA Gene Mutation?

What is a BRCA Gene Mutation?

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• published: 03 Jun 2015
• views: 24314

In this video, genetic counselor Joyce Turner, MSC, CGC, explains what the BRCA1 and BRCA2 genes are and how a mutation in either gene can lead to cancer. She also discusses how genetic counseling and testing can help women make informed decisions about their health. This video can also be viewed at http://www.cdc.gov/cancer/videos/breast/BringYourBrave/Genetic_Counselor/WhatIsBRCAGeneMutation/WhatIsBRCAGeneMutation_lowRes.mp4

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3:50

BRCA gene test questioned after unnecessary surgeries

Seven women in one family had major surgery after a widely used genetic test, taken by hun...

published: 24 Dec 2019

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BRCA gene test questioned after unnecessary surgeries

BRCA gene test questioned after unnecessary surgeries

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• published: 24 Dec 2019
• views: 6526

Seven women in one family had major surgery after a widely used genetic test, taken by hundreds of thousands of people, showed a high cancer risk. One of them says she was left debilitated and unable to have more children. But, years later, the family has learned the results of that BRCA test might have been wrong. Jamie Yuccas reports. Watch "CBS This Morning" HERE: http://bit.ly/1T88yAR Download the CBS News app on iOS HERE: https://apple.co/1tRNnUy Download the CBS News app on Android HERE: https://bit.ly/1IcphuX Like "CBS This Morning" on Facebook HERE: http://on.fb.me/1LhtdvI Follow "CBS This Morning" on Twitter HERE: http://bit.ly/1Xj5W3p Follow "CBS This Morning" on Instagram HERE: http://bit.ly/1Q7NGnY Get new episodes of shows you love across devices the next day, stream local news live, and watch full seasons of CBS fan favorites anytime, anywhere with CBS All Access. Try it free! http://bit.ly/1OQA29B Each weekday morning, "CBS This Morning" co-hosts Gayle King, Anthony Mason and Tony Dokoupil deliver two hours of original reporting, breaking news and top-level newsmaker interviews in an engaging and informative format that challenges the norm in network morning news programs. The broadcast has earned a prestigious Peabody Award, a Polk Award, four News & Documentary Emmys, three Daytime Emmys and the 2017 Edward R. Murrow Award for Best Newscast. The broadcast was also honored with an Alfred I. duPont-Columbia Award as part of CBS News division-wide coverage of the shootings at Sandy Hook Elementary School in Newtown, Connecticut. Check local listings for "CBS This Morning" broadcast times.

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9:46

Therapeutic Supports for Young BRCA1/BRCA2 patients | Jessica Baglieri | TEDxCarletonUniversity

In her talk, Jessica Baglieri introduces the audience to BRCA1/BRCA2 genetic mutations, sh...

published: 02 Mar 2023

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Therapeutic Supports for Young BRCA1/BRCA2 patients | Jessica Baglieri | TEDxCarletonUniversity

Therapeutic Supports for Young BRCA1/BRCA2 patients | Jessica Baglieri | TEDxCarletonUniversity

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• published: 02 Mar 2023
• views: 389

In her talk, Jessica Baglieri introduces the audience to BRCA1/BRCA2 genetic mutations, shares what it is like to receive a diagnosis for one of these mutations, and discusses the need for more mental and physical support for those who have these mutations Jessica Baglieri is currently conducting research on the lived experiences of young BRCA patients and their needs. Baglieri hopes to combine her lived experience, experience as a youth mental health worker, and her research on exploring the mental and emotional needs of young women with a BRCA1/2 diagnosis to create a system that better supports the holistic needs of young BRCA patients. This talk was given at a TEDx event using the TED conference format but independently organized by a local community. Learn more at https://www.ted.com/tedx

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BRCA mutation

A BRCA mutation is a mutation in either of the BRCA1 and BRCA2 genes, which are tumor suppressor genes. Hundreds of different types of mutations in these genes have been identified, some of which have been determined to be harmful, while others have no proven impact. Harmful mutations in these genes may produce a hereditary breast-ovarian cancer syndrome in affected persons. Only 5-10% of breast cancer cases in women are attributed to BRCA1 and BRCA2 mutations (with BRCA1 mutations being slightly more common than BRCA2 mutations), but the impact on women with the gene mutation is more profound. Women with harmful mutations in either BRCA1 or BRCA2 have a risk of breast cancer that is about five times the normal risk, and a risk of ovarian cancer that is about ten to thirty times normal. The risk of breast and ovarian cancer is higher for women with a high-risk BRCA1 mutation than with a BRCA2 mutation. Having a high-risk mutation does not guarantee that the woman will develop any type of cancer, or imply that any cancer that appears was actually caused by the mutation, rather than some other factor.

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This page contains text from Wikipedia, the Free Encyclopedia - https://wn.com/BRCA_mutation

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BRCA1 and BRCA2 Mutations & Cancer (Types of Cance...

The Role of BRCA1 in Cancer...

Understanding BRCA1 and BRCA2: What These Mutation...

What is BRCA1 and BRCA2?...

Understanding BRCA Mutations and Risk...

BRCA mutation...

We All Tested Positive for BRCA...

What is a BRCA Gene Mutation?...

BRCA gene test questioned after unnecessary surger...

Therapeutic Supports for Young BRCA1/BRCA2 patient...

Latest News for: brca mutation

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77 Facts That Blew Our Minds in 2024

The Atlantic 28 Dec 2024

We’ve reported on the quirks of animal behavior and the latest in psychedelics research ... We hope they blow your mind too ... Fresh corpses, they devour ... BRCA mutations, famously linked to breast cancer, can also lead to cancer in the pancreas and prostate.

Edit

Biodegradable nanoparticles enable simultaneous delivery of two drugs to attack tumors

Phys Dot Org 23 Dec 2024

BRAF and MEK inhibitors used to treat melanoma (skin cancer) with a BRAF gene mutation (present in 50% of melanoma cases), and PARP and PD-L1 inhibitors intended for breast cancer with a BRCA gene mutation or deficiency.

Edit

Thousands of women with breast cancer may soon be told they don't need ANY treatment... ...

The Daily Mail 22 Dec 2024

Famously, actress Angelina Jolie discovered she carried the BRCA mutation, and underwent a preventative mastectomy in 2013 to reduce her risk of the disease.

Edit

This Christmas, ask for genetic testing. It could save your life.

Usatoday 18 Dec 2024

Physicians have been testing for the BRCA genes for about 20 years, according to Dr ... Scientists developed drugs called PARP inhibitors that treat cancers stemming from the BRCA gene mutations such as breast and ovarian cancer.

Edit

Breast, Ovary Removal Can Lengthen Lives of Women With Breast Cancer Genes

Potter Leader-Enterprise 13 Dec 2024

Young breast cancer patients with high-risk BRCA mutations can benefit from having their breasts or ovaries removed ... The National Cancer Institute has more on BRCA mutations and cancer.

Edit

Prostate Cancer Market Expected to Experience Major Growth by 2034, According to DelveInsight | Bayer, ...

GetNews 13 Dec 2024

In September 2024, Foundation Medicine has obtained FDA approval for its FoundationOne®CDx and Liquid CDx as companion diagnostic tools for identifying BRCA-mutated metastatic castration-resistant ...

Edit

‘Alarming’ rise of late-stage breast cancer is even worse in women under 40, new study finds

New York Post 11 Dec 2024

Further, mutations on BRCA1 or BRCA2 genes are more common in young ... Six percent of all breast cancer patients carry BRCA gene mutations; however, in patients under 45, roughly 12% carry the gene.

Edit

Prostate cancer: New treatments that every man over 40 needs to know today

Hindustan Times 07 Dec 2024

According to health experts, prostate cancer is a significant health concern, especially for men with certain inherited genetic traits like BRCA gene mutations and Lynch syndrome, which elevate their risk.

Edit

Top 5 genetic factors that affect breast cancer risk

The Times of India 02 Dec 2024

Genetic testing for BRCA and other mutations allows individuals to assess their risk and explore preventive options, including enhanced screening and, in some cases, preventive surgeries.

Edit

Understanding and navigating genetic risks for cancer

The Times of India 28 Nov 2024

BRCA1 and BRCA2 Mutations ... While women are more susceptible to breast cancer with these mutations, men who possess the BRCA gene are at a higher risk of developing prostate Cancer.2 ... TP53 Gene Mutation ... APC Gene Mutation ... RET Gene Mutation.

Edit

For women using IVF to screen embryos for genetic diseases, these peers can offer support

Jewish Herald Voice 27 Nov 2024

Another woman who carries the BRCA mutation, A., said she decided to do PGT despite the cost and the fact that it’s “physically, emotionally and mentally wearing on your body.” Both she and her mother ...

photo: Creative Commons / Ryan Jeffs https://commons.wikimedia.org/w/index.php?title=User:Rjeffs&action=edit&redlink=1

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Big hope for cancer: How the Nobel-winning discovery of microRNA is changing the face of diagnosis and therapies

Financial Express 25 Nov 2024

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The role of genetics in pancreatic cancer: Are you at risk?

The Times of India 22 Nov 2024

Among targeted therapies in BRCA-mutated pancreatic cancers that are approved by the FDA, there are PARP inhibitors, such as olaparib and rucaparib, which exploit defective DNA repair and ...

Edit

Understanding the rise in young-onset pancreatic cancer: Causes and concerns

The Times of India 22 Nov 2024

The change only emphasizes the importance of fighting the disease and reveals the problems of young patients at the same time ... Some of the identified risk factors include, hereditary that is associated with the BRCA mutations ... Dr.

Edit

The ‘Breast-Cancer Gene’ Needs a Rebrand

The Atlantic 20 Nov 2024

A 2013 New York Times op-ed in which Angelina Jolie revealed she’d had a preventive double mastectomy because of her own BRCA mutation drove many women to seek DNA tests themselves ... mutations on men.

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