-
BRCA1 and BRCA2 Mutations & Cancer (Types of Cancer, and Who’s Most At Risk)
REUPLOADING TO FIX VIDEO ISSUE
BRCA1 and BRCA2 Mutations & Cancer (Types of Cancer, and Who’s Most At Risk)
BRCA1 and BRCA2 are genes involved in DNA repair and other important functions. However, mutations in BRCA1 and BRCA2 increase the risk of different types of cancer, including breast and ovarian cancer. In this lesson, we discuss the roles of normal functioning BRCA, different patient populations most at risk, different mutations, and different types of associated cancer.
I hope you find this lesson helpful. If you do, please like and subscribe for more lessons like this one!
JJ
**MEDICAL LEGAL DISCLAIMER**: JJ Medicine does not provide medical advice, and the information available on this channel does not offer a diagnosis or advice regarding treatment. Information presented in...
published: 27 Jul 2022
-
BRCA mutation
This breast cancer lecture explains about the brca gene (brca1 and brca2 mechanism) mutation which leads to the development of breast cancer.
A BRCA mutation is a mutation in both of the genes BRCA1 and BRCA2. Detrimental mutations in these tumor suppressor genes produce a hereditary breast-ovarian melanoma syndrome in affected families. Mutations in BRCA1 and BRCA2 are distinctive, and breast cancer is relatively original, so these mutations consequently account for only five to ten percent of all breast cancer cases in women.
1000s of distinctive types of mutations in these genes have been recognized. Excessive-danger mutations, which disable an primary error-free DNA repair procedure (homology directed repair), tremendously develop the character's threat of setting up breast cancer, ov...
published: 01 Apr 2015
-
BRCA Genes and Breast Cancer
Genetic counselor Joyce Turner, MSC, CGC, provides an overview of BRCA genes and their relationship to breast and ovarian cancer. She explains how each of us inherits BRCA genes from our parents, the role of those genes and what happens if we inherit a gene mutation. She also talks about how genetic counseling and testing can give a woman information she can use to make decisions about her health.
Comments on this video are allowed in accordance with our comment policy: http://www.cdc.gov/SocialMedia/Tools/CommentPolicy.html
This video can also be viewed at
http://www.cdc.gov/cancer/videos/breast/BringYourBrave/Genetic_Counselor/BRCAGenesBreastCancer/BRCAGenesBreastCancer_lowRes.mp4
published: 28 May 2015
-
What is a BRCA Gene Mutation?
In this video, genetic counselor Joyce Turner, MSC, CGC, explains what the BRCA1 and BRCA2 genes are and how a mutation in either gene can lead to cancer. She also discusses how genetic counseling and testing can help women make informed decisions about their health.
This video can also be viewed at
http://www.cdc.gov/cancer/videos/breast/BringYourBrave/Genetic_Counselor/WhatIsBRCAGeneMutation/WhatIsBRCAGeneMutation_lowRes.mp4
published: 03 Jun 2015
-
BRCA Genetic Testing: What to Know & Why Its Important
We teach how to identify if you are at risk for the BRCA genetic mutation. If you carry this “breast cancer gene mutation” you are at an increased risk for breast and other certain types of cancer.
VISIT THE BREAST CANCER SCHOOL FOR PATIENTS:
http://www.breastcancercourse.org
LIST OF QUESTIONS FOR YOUR DOCTORS:
http://www.breastcancercourse.org/breast-health-updates-latest-videos/
FOLLOW US:
Facebook: https://www.facebook.com/Breast-Cancer-School-for-Patients-958519147618444/
__________________________________
Questions for your Breast Surgeon and Medical Oncologist:
1. Do I qualify for BRCA genetic testing?
2. If so, will you order genetic testing for me?
3. Would genetic testing before surgery change our plans?
4. What is the downside of BRCA testing?
5. Will you also order “Multi...
published: 26 Mar 2018
-
Understanding BRCA Mutations and Risk
BRCA1 and BRCA2 are breast cancer gene mutations. When a mutation occurs, the gene doesn’t function properly, DNA errors don’t get repaired, and the risk of cancer increases. A genetic counselor will review your family histories, discuss the testing process, and explain benefits as well as the risks of learning about a genetic mutation that may increase your cancer risk.
published: 14 Apr 2017
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BRCA gene test questioned after unnecessary surgeries
Seven women in one family had major surgery after a widely used genetic test, taken by hundreds of thousands of people, showed a high cancer risk. One of them says she was left debilitated and unable to have more children. But, years later, the family has learned the results of that BRCA test might have been wrong. Jamie Yuccas reports.
Watch "CBS This Morning" HERE: http://bit.ly/1T88yAR
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Get new episodes of shows you love across devices the next day, stream local ne...
published: 24 Dec 2019
-
فلتر الاعلام #fcbarcelona #اكسبلور #العراق #football #ترند #ترند_تيك_توك #ترندات #ترند_السعودية
published: 18 Jun 2024
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How Can I Prevent Cancer If I Have a BRCA Mutation? | Dana-Farber Cancer Institute
Dr. Garber, director of the Center for Cancer Genetics and Prevention at Dana-Farber, discusses ways to prevent cancer for those who carry a BRCA mutation.
published: 04 Dec 2015
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Lisa: My Experience with BRCA Counseling and Testing
Lisa, age 40, talks about how her family history led her to get genetic counseling and testing for BRCA gene mutations. She describes the genetic testing experience, and how it helped her understand her family history and manage her risk for breast cancer.
Comments on this video are allowed in accordance with our comment policy: http://www.cdc.gov/SocialMedia/Tools/CommentPolicy.html
This video can also be viewed at
http://www.cdc.gov/cancer/videos/breast/BringYourBrave/Lisa/MyExperienceCT/MyExperienceCT_lowRes.mp4
published: 28 May 2015
8:37
BRCA1 and BRCA2 Mutations & Cancer (Types of Cancer, and Who’s Most At Risk)
REUPLOADING TO FIX VIDEO ISSUE
BRCA1 and BRCA2 Mutations & Cancer (Types of Cancer, and Who’s Most At Risk)
BRCA1 and BRCA2 are genes involved in DNA repair a...
REUPLOADING TO FIX VIDEO ISSUE
BRCA1 and BRCA2 Mutations & Cancer (Types of Cancer, and Who’s Most At Risk)
BRCA1 and BRCA2 are genes involved in DNA repair and other important functions. However, mutations in BRCA1 and BRCA2 increase the risk of different types of cancer, including breast and ovarian cancer. In this lesson, we discuss the roles of normal functioning BRCA, different patient populations most at risk, different mutations, and different types of associated cancer.
I hope you find this lesson helpful. If you do, please like and subscribe for more lessons like this one!
JJ
**MEDICAL LEGAL DISCLAIMER**: JJ Medicine does not provide medical advice, and the information available on this channel does not offer a diagnosis or advice regarding treatment. Information presented in these lessons is for educational purposes ONLY, and information presented here is not to be used as an alternative to a healthcare professional’s diagnosis and treatment of any person/animal. Only a physician or other licensed healthcare professional are able to determine the requirement for medical assistance to be given to a patient. Please seek the advice of your physician or other licensed healthcare provider if you have any questions regarding a medical condition.
*AFFILIATE DISCLAIMER: This YouTube Channel uses affiliate links and may earn a commission from associated sales.
*IMAGE DISCLAIMER: The content (ex. images) used in this lesson are used in accordance with Fair Use laws and are intended for educational/teaching purposes only*
*Subscribe for more free medical lessons* https://www.youtube.com/channel/UCFPvnkCZbHfBvV8ApBBE0vA?sub_confirmation=1
-------------------------------------------------------------------------------------------------------------
For books and more information on these topics
https://www.amazon.com/shop/jjmedicine
Support future lessons and lectures ➜ https://www.patreon.com/jjmedicine
Check out the best tool to help grow your YouTube channel (it’s helped me!)
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Follow me on Twitter! ➜ https://twitter.com/JJ_Medicine
Come join me on Facebook! ➜ https://www.facebook.com/JJ-Medicine-100642648161192/
------------------------------------------------------------------------------------------------------------
*Check Out Some of My Other Lessons*
Medical Terminology - The Basics - Lesson 1:
https://www.youtube.com/watch?v=04Wh2E9oNug
Infectious Disease Playlist
https://www.youtube.com/playlist?list=PLRjNoiRtdFwW0Bkc6c66uDACkzotaK26b
Dermatology Playlist
https://www.youtube.com/playlist?list=PLRjNoiRtdFwW3dgORRNmk_MZvnWpZx_lW
Pharmacology Playlist
https://www.youtube.com/playlist?list=PLRjNoiRtdFwWPWcV9lZTh-Qxv0gYakQXR
Hematology Playlist
https://www.youtube.com/playlist?list=PLRjNoiRtdFwW8Ajo1dmxdj4EYEKcbtGju
Rheumatology Playlist
https://www.youtube.com/playlist?list=PLRjNoiRtdFwWDvuhasXsuTFXJp05wwUle
Endocrinology Playlist
https://www.youtube.com/playlist?list=PLRjNoiRtdFwUuRSzhploohnaWVvbVZ7ZP
Nephrology Playlist
https://www.youtube.com/playlist?list=PLRjNoiRtdFwXRSwrFQK5WwWZLk1Las8v8
Fatty Acid Synthesis Pathway:
https://www.youtube.com/watch?v=WuQS_LpNMzo
Wnt/B Catenin Signaling Pathway:
https://www.youtube.com/watch?v=NGVP4J9jpgs
Upper vs. Lower Motor Neuron Lesions:
https://www.youtube.com/watch?v=itNd74V53ng
Lesson on the Purine Synthesis and Salvage Pathway:
https://www.youtube.com/watch?v=e2KFVvI8Akk
Gastrulation | Formation of Germ Layers:
https://www.youtube.com/watch?v=d6Kkn0SECJ4
Introductory lesson on Autophagy (Macroautophagy):
https://www.youtube.com/watch?v=UmSVKzHc5yA
https://wn.com/Brca1_And_Brca2_Mutations_Cancer_(Types_Of_Cancer,_And_Who’S_Most_At_Risk)
REUPLOADING TO FIX VIDEO ISSUE
BRCA1 and BRCA2 Mutations & Cancer (Types of Cancer, and Who’s Most At Risk)
BRCA1 and BRCA2 are genes involved in DNA repair and other important functions. However, mutations in BRCA1 and BRCA2 increase the risk of different types of cancer, including breast and ovarian cancer. In this lesson, we discuss the roles of normal functioning BRCA, different patient populations most at risk, different mutations, and different types of associated cancer.
I hope you find this lesson helpful. If you do, please like and subscribe for more lessons like this one!
JJ
**MEDICAL LEGAL DISCLAIMER**: JJ Medicine does not provide medical advice, and the information available on this channel does not offer a diagnosis or advice regarding treatment. Information presented in these lessons is for educational purposes ONLY, and information presented here is not to be used as an alternative to a healthcare professional’s diagnosis and treatment of any person/animal. Only a physician or other licensed healthcare professional are able to determine the requirement for medical assistance to be given to a patient. Please seek the advice of your physician or other licensed healthcare provider if you have any questions regarding a medical condition.
*AFFILIATE DISCLAIMER: This YouTube Channel uses affiliate links and may earn a commission from associated sales.
*IMAGE DISCLAIMER: The content (ex. images) used in this lesson are used in accordance with Fair Use laws and are intended for educational/teaching purposes only*
*Subscribe for more free medical lessons* https://www.youtube.com/channel/UCFPvnkCZbHfBvV8ApBBE0vA?sub_confirmation=1
-------------------------------------------------------------------------------------------------------------
For books and more information on these topics
https://www.amazon.com/shop/jjmedicine
Support future lessons and lectures ➜ https://www.patreon.com/jjmedicine
Check out the best tool to help grow your YouTube channel (it’s helped me!)
https://www.tubebuddy.com/jjmedicine
Follow me on Twitter! ➜ https://twitter.com/JJ_Medicine
Come join me on Facebook! ➜ https://www.facebook.com/JJ-Medicine-100642648161192/
------------------------------------------------------------------------------------------------------------
*Check Out Some of My Other Lessons*
Medical Terminology - The Basics - Lesson 1:
https://www.youtube.com/watch?v=04Wh2E9oNug
Infectious Disease Playlist
https://www.youtube.com/playlist?list=PLRjNoiRtdFwW0Bkc6c66uDACkzotaK26b
Dermatology Playlist
https://www.youtube.com/playlist?list=PLRjNoiRtdFwW3dgORRNmk_MZvnWpZx_lW
Pharmacology Playlist
https://www.youtube.com/playlist?list=PLRjNoiRtdFwWPWcV9lZTh-Qxv0gYakQXR
Hematology Playlist
https://www.youtube.com/playlist?list=PLRjNoiRtdFwW8Ajo1dmxdj4EYEKcbtGju
Rheumatology Playlist
https://www.youtube.com/playlist?list=PLRjNoiRtdFwWDvuhasXsuTFXJp05wwUle
Endocrinology Playlist
https://www.youtube.com/playlist?list=PLRjNoiRtdFwUuRSzhploohnaWVvbVZ7ZP
Nephrology Playlist
https://www.youtube.com/playlist?list=PLRjNoiRtdFwXRSwrFQK5WwWZLk1Las8v8
Fatty Acid Synthesis Pathway:
https://www.youtube.com/watch?v=WuQS_LpNMzo
Wnt/B Catenin Signaling Pathway:
https://www.youtube.com/watch?v=NGVP4J9jpgs
Upper vs. Lower Motor Neuron Lesions:
https://www.youtube.com/watch?v=itNd74V53ng
Lesson on the Purine Synthesis and Salvage Pathway:
https://www.youtube.com/watch?v=e2KFVvI8Akk
Gastrulation | Formation of Germ Layers:
https://www.youtube.com/watch?v=d6Kkn0SECJ4
Introductory lesson on Autophagy (Macroautophagy):
https://www.youtube.com/watch?v=UmSVKzHc5yA
- published: 27 Jul 2022
- views: 60041
17:32
BRCA mutation
This breast cancer lecture explains about the brca gene (brca1 and brca2 mechanism) mutation which leads to the development of breast cancer.
A BRCA mutation is...
This breast cancer lecture explains about the brca gene (brca1 and brca2 mechanism) mutation which leads to the development of breast cancer.
A BRCA mutation is a mutation in both of the genes BRCA1 and BRCA2. Detrimental mutations in these tumor suppressor genes produce a hereditary breast-ovarian melanoma syndrome in affected families. Mutations in BRCA1 and BRCA2 are distinctive, and breast cancer is relatively original, so these mutations consequently account for only five to ten percent of all breast cancer cases in women.
1000s of distinctive types of mutations in these genes have been recognized. Excessive-danger mutations, which disable an primary error-free DNA repair procedure (homology directed repair), tremendously develop the character's threat of setting up breast cancer, ovarian melanoma and specific different cancers. Why BRCA1 and BRCA2 mutations lead preferentially to cancers of the breast and ovary is not identified, but lack of BRCA1 function seems to result in non-useful x-chromosome inactivation. No longer all mutations are excessive-chance; some show up to be harmless editions. The cancer hazard related to any given mutation varies greatly and depends on the distinctive variety and area of the mutation and in all probability different person reasons.
Ladies with unsafe mutations in either BRCA1 or BRCA2 have risk of breast melanoma that is about five occasions the average chance, and a hazard of ovarian cancer that's about ten to thirty occasions common. BRCA1 mutations typically confer a higher danger of breast and ovarian melanoma in females than BRCA2 mutations. Having a high-threat mutation does no longer guarantee that the girl will increase any sort of cancer, or warranty that any melanoma that appears was once genuinely induced through the mutation, alternatively than every other element, like alcohol consumption.
For more information, log on to-
http://www.shomusbiology.com/
Get Shomu's Biology DVD set here-
http://www.shomusbiology.com/dvd-store/
Download the study materials here-
http://shomusbiology.com/bio-materials.html
Remember Shomu’s Biology is created to spread the knowledge of life science and biology by sharing all this free biology lectures video and animation presented by Suman Bhattacharjee in YouTube. All these tutorials are brought to you for free. Please subscribe to our channel so that we can grow together. You can check for any of the following services from Shomu’s Biology-
Buy Shomu’s Biology lecture DVD set- www.shomusbiology.com/dvd-store
Shomu’s Biology assignment services – www.shomusbiology.com/assignment -help
Join Online coaching for CSIR NET exam – www.shomusbiology.com/net-coaching
We are social. Find us on different sites here-
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Thank you for watching
https://wn.com/Brca_Mutation
This breast cancer lecture explains about the brca gene (brca1 and brca2 mechanism) mutation which leads to the development of breast cancer.
A BRCA mutation is a mutation in both of the genes BRCA1 and BRCA2. Detrimental mutations in these tumor suppressor genes produce a hereditary breast-ovarian melanoma syndrome in affected families. Mutations in BRCA1 and BRCA2 are distinctive, and breast cancer is relatively original, so these mutations consequently account for only five to ten percent of all breast cancer cases in women.
1000s of distinctive types of mutations in these genes have been recognized. Excessive-danger mutations, which disable an primary error-free DNA repair procedure (homology directed repair), tremendously develop the character's threat of setting up breast cancer, ovarian melanoma and specific different cancers. Why BRCA1 and BRCA2 mutations lead preferentially to cancers of the breast and ovary is not identified, but lack of BRCA1 function seems to result in non-useful x-chromosome inactivation. No longer all mutations are excessive-chance; some show up to be harmless editions. The cancer hazard related to any given mutation varies greatly and depends on the distinctive variety and area of the mutation and in all probability different person reasons.
Ladies with unsafe mutations in either BRCA1 or BRCA2 have risk of breast melanoma that is about five occasions the average chance, and a hazard of ovarian cancer that's about ten to thirty occasions common. BRCA1 mutations typically confer a higher danger of breast and ovarian melanoma in females than BRCA2 mutations. Having a high-threat mutation does no longer guarantee that the girl will increase any sort of cancer, or warranty that any melanoma that appears was once genuinely induced through the mutation, alternatively than every other element, like alcohol consumption.
For more information, log on to-
http://www.shomusbiology.com/
Get Shomu's Biology DVD set here-
http://www.shomusbiology.com/dvd-store/
Download the study materials here-
http://shomusbiology.com/bio-materials.html
Remember Shomu’s Biology is created to spread the knowledge of life science and biology by sharing all this free biology lectures video and animation presented by Suman Bhattacharjee in YouTube. All these tutorials are brought to you for free. Please subscribe to our channel so that we can grow together. You can check for any of the following services from Shomu’s Biology-
Buy Shomu’s Biology lecture DVD set- www.shomusbiology.com/dvd-store
Shomu’s Biology assignment services – www.shomusbiology.com/assignment -help
Join Online coaching for CSIR NET exam – www.shomusbiology.com/net-coaching
We are social. Find us on different sites here-
Our Website – www.shomusbiology.com
Facebook page- https://www.facebook.com/ShomusBiology/
Twitter - https://twitter.com/shomusbiology
SlideShare- www.slideshare.net/shomusbiology
Google plus- https://plus.google.com/113648584982732129198
LinkedIn - https://www.linkedin.com/in/suman-bhattacharjee-2a051661
Youtube- https://www.youtube.com/user/TheFunsuman
Thank you for watching
- published: 01 Apr 2015
- views: 68336
3:12
BRCA Genes and Breast Cancer
Genetic counselor Joyce Turner, MSC, CGC, provides an overview of BRCA genes and their relationship to breast and ovarian cancer. She explains how each of us in...
Genetic counselor Joyce Turner, MSC, CGC, provides an overview of BRCA genes and their relationship to breast and ovarian cancer. She explains how each of us inherits BRCA genes from our parents, the role of those genes and what happens if we inherit a gene mutation. She also talks about how genetic counseling and testing can give a woman information she can use to make decisions about her health.
Comments on this video are allowed in accordance with our comment policy: http://www.cdc.gov/SocialMedia/Tools/CommentPolicy.html
This video can also be viewed at
http://www.cdc.gov/cancer/videos/breast/BringYourBrave/Genetic_Counselor/BRCAGenesBreastCancer/BRCAGenesBreastCancer_lowRes.mp4
https://wn.com/Brca_Genes_And_Breast_Cancer
Genetic counselor Joyce Turner, MSC, CGC, provides an overview of BRCA genes and their relationship to breast and ovarian cancer. She explains how each of us inherits BRCA genes from our parents, the role of those genes and what happens if we inherit a gene mutation. She also talks about how genetic counseling and testing can give a woman information she can use to make decisions about her health.
Comments on this video are allowed in accordance with our comment policy: http://www.cdc.gov/SocialMedia/Tools/CommentPolicy.html
This video can also be viewed at
http://www.cdc.gov/cancer/videos/breast/BringYourBrave/Genetic_Counselor/BRCAGenesBreastCancer/BRCAGenesBreastCancer_lowRes.mp4
- published: 28 May 2015
- views: 44686
1:28
What is a BRCA Gene Mutation?
In this video, genetic counselor Joyce Turner, MSC, CGC, explains what the BRCA1 and BRCA2 genes are and how a mutation in either gene can lead to cancer. She ...
In this video, genetic counselor Joyce Turner, MSC, CGC, explains what the BRCA1 and BRCA2 genes are and how a mutation in either gene can lead to cancer. She also discusses how genetic counseling and testing can help women make informed decisions about their health.
This video can also be viewed at
http://www.cdc.gov/cancer/videos/breast/BringYourBrave/Genetic_Counselor/WhatIsBRCAGeneMutation/WhatIsBRCAGeneMutation_lowRes.mp4
https://wn.com/What_Is_A_Brca_Gene_Mutation
In this video, genetic counselor Joyce Turner, MSC, CGC, explains what the BRCA1 and BRCA2 genes are and how a mutation in either gene can lead to cancer. She also discusses how genetic counseling and testing can help women make informed decisions about their health.
This video can also be viewed at
http://www.cdc.gov/cancer/videos/breast/BringYourBrave/Genetic_Counselor/WhatIsBRCAGeneMutation/WhatIsBRCAGeneMutation_lowRes.mp4
- published: 03 Jun 2015
- views: 24314
14:51
BRCA Genetic Testing: What to Know & Why Its Important
We teach how to identify if you are at risk for the BRCA genetic mutation. If you carry this “breast cancer gene mutation” you are at an increased risk for brea...
We teach how to identify if you are at risk for the BRCA genetic mutation. If you carry this “breast cancer gene mutation” you are at an increased risk for breast and other certain types of cancer.
VISIT THE BREAST CANCER SCHOOL FOR PATIENTS:
http://www.breastcancercourse.org
LIST OF QUESTIONS FOR YOUR DOCTORS:
http://www.breastcancercourse.org/breast-health-updates-latest-videos/
FOLLOW US:
Facebook: https://www.facebook.com/Breast-Cancer-School-for-Patients-958519147618444/
__________________________________
Questions for your Breast Surgeon and Medical Oncologist:
1. Do I qualify for BRCA genetic testing?
2. If so, will you order genetic testing for me?
3. Would genetic testing before surgery change our plans?
4. What is the downside of BRCA testing?
5. Will you also order “Multi-Gene Panel”?
6. What is “The Breast Cancer Gene?”
The BRCA (Breast Cancer) gene is commonly referred to as “The Breast Cancer Gene.” If someone inherits a broken version of this gene (known as a “mutation”) at conception, they carry a significantly increased lifetime risk of breast cancer and ovarian cancer. This gene “mutation” can come from either their mother or father. Most breast cancers are not the result of BRCA mutations. In fact, it is estimated that BRCA and similar genetic mutations cause only 5 to 10% of all breast cancers.
If you are a woman and test “positive” for a BRCA mutation, your physicians can advise you how to reduce your risk of developing breast and ovarian cancer in the future. There are excellent prevention strategies to lessen your cancer risk. There are also enhanced screening options to detect cancers earlier when they are more curable. You must be your own advocate to find out if you are a candidate for genetic testing.
This is the condition that was widely reported in the media when celebrity Angelina Jolie announced that she had mastectomies and reconstruction of both her breasts to reduce her personal risk of developing breast cancer. Although she did not have breast cancer, she tested positive for the BRCA mutation. She underwent testing because she had a strong history of breast and ovarian cancer in her family.
Should I ask about BRCA testing before surgery?
You need to ask yourself this question, “If I have cancer and carry a BRCA mutation, would I change my mind about surgery and have both breasts removed to reduce my risk of having another new breast cancer in the future?” If the answer is yes or maybe, you should consider undergoing the testing before your recommended surgery. If the answer is no, you can undergo testing after surgery, if desired.
Both men and women are at equal risk for carrying the BRCA mutation. Women are more commonly identified as “High Risk” for BRCA mutations because they may have been diagnosed with breast or ovarian cancer and are more often asked if they have a family history of these cancers. But it is important that men also learn if they are at high risk for cancer causing mutations and pursue genetic counseling. You may qualify for BRCA genetic testing if you have:
Below is a very simplified list of the most common qualifying risk factors.
*Breast cancer diagnosed at 50 or younger
*Ovarian cancer at any age
*A family member with a “BRCA mutation”
*A strong family history of breast, ovarian, prostate or pancreatic cancer
*Breast cancer in both breasts
*Male breast cancer at any age
*“Triple negative” breast cancer before age 60
*Ashkenazi Jewish ancestry and breast or pancreatic cancer
We list detailed references and links on our website, www.breastcancercourse.org to several national guidelines. Always obtain formal genetic counseling with a qualified physician or certified genetic counselor before undergoing BRCA and genetic testing..
Multi-Gene Panel Testing
Although the majority of “hereditary” breast cancer is likely due to the BRCA genes, other gene mutations could be present that also cause an increased risk for breast and other types of cancers. “Multi-Gene Panel Tests” evaluate multiple other cancer-causing genes at the same time as BRCA testing. We recommend considering “Panel Testing” be included with BRCA testing. There is usually no additional cost for adding this test to BRCA genetic screening.
What are the downsides to genetic testing?
It is important to note that if someone carries the BRCA mutation, that does not mean they will develop cancer. Genetic testing can open a “Pandora’s Box” of unanswerable questions. Everyone has a unique philosophy of life and belief system. Many decline genetic testing for personal reasons. Unfortunately, too many men and women at risk for genetic mutations are never offered genetic counselling. A recent study in the Journal of the American Medical Association found that many women with newly diagnosed breast cancer and at a high risk for genetic mutations are not offered genetic counseling.
https://wn.com/Brca_Genetic_Testing_What_To_Know_Why_Its_Important
We teach how to identify if you are at risk for the BRCA genetic mutation. If you carry this “breast cancer gene mutation” you are at an increased risk for breast and other certain types of cancer.
VISIT THE BREAST CANCER SCHOOL FOR PATIENTS:
http://www.breastcancercourse.org
LIST OF QUESTIONS FOR YOUR DOCTORS:
http://www.breastcancercourse.org/breast-health-updates-latest-videos/
FOLLOW US:
Facebook: https://www.facebook.com/Breast-Cancer-School-for-Patients-958519147618444/
__________________________________
Questions for your Breast Surgeon and Medical Oncologist:
1. Do I qualify for BRCA genetic testing?
2. If so, will you order genetic testing for me?
3. Would genetic testing before surgery change our plans?
4. What is the downside of BRCA testing?
5. Will you also order “Multi-Gene Panel”?
6. What is “The Breast Cancer Gene?”
The BRCA (Breast Cancer) gene is commonly referred to as “The Breast Cancer Gene.” If someone inherits a broken version of this gene (known as a “mutation”) at conception, they carry a significantly increased lifetime risk of breast cancer and ovarian cancer. This gene “mutation” can come from either their mother or father. Most breast cancers are not the result of BRCA mutations. In fact, it is estimated that BRCA and similar genetic mutations cause only 5 to 10% of all breast cancers.
If you are a woman and test “positive” for a BRCA mutation, your physicians can advise you how to reduce your risk of developing breast and ovarian cancer in the future. There are excellent prevention strategies to lessen your cancer risk. There are also enhanced screening options to detect cancers earlier when they are more curable. You must be your own advocate to find out if you are a candidate for genetic testing.
This is the condition that was widely reported in the media when celebrity Angelina Jolie announced that she had mastectomies and reconstruction of both her breasts to reduce her personal risk of developing breast cancer. Although she did not have breast cancer, she tested positive for the BRCA mutation. She underwent testing because she had a strong history of breast and ovarian cancer in her family.
Should I ask about BRCA testing before surgery?
You need to ask yourself this question, “If I have cancer and carry a BRCA mutation, would I change my mind about surgery and have both breasts removed to reduce my risk of having another new breast cancer in the future?” If the answer is yes or maybe, you should consider undergoing the testing before your recommended surgery. If the answer is no, you can undergo testing after surgery, if desired.
Both men and women are at equal risk for carrying the BRCA mutation. Women are more commonly identified as “High Risk” for BRCA mutations because they may have been diagnosed with breast or ovarian cancer and are more often asked if they have a family history of these cancers. But it is important that men also learn if they are at high risk for cancer causing mutations and pursue genetic counseling. You may qualify for BRCA genetic testing if you have:
Below is a very simplified list of the most common qualifying risk factors.
*Breast cancer diagnosed at 50 or younger
*Ovarian cancer at any age
*A family member with a “BRCA mutation”
*A strong family history of breast, ovarian, prostate or pancreatic cancer
*Breast cancer in both breasts
*Male breast cancer at any age
*“Triple negative” breast cancer before age 60
*Ashkenazi Jewish ancestry and breast or pancreatic cancer
We list detailed references and links on our website, www.breastcancercourse.org to several national guidelines. Always obtain formal genetic counseling with a qualified physician or certified genetic counselor before undergoing BRCA and genetic testing..
Multi-Gene Panel Testing
Although the majority of “hereditary” breast cancer is likely due to the BRCA genes, other gene mutations could be present that also cause an increased risk for breast and other types of cancers. “Multi-Gene Panel Tests” evaluate multiple other cancer-causing genes at the same time as BRCA testing. We recommend considering “Panel Testing” be included with BRCA testing. There is usually no additional cost for adding this test to BRCA genetic screening.
What are the downsides to genetic testing?
It is important to note that if someone carries the BRCA mutation, that does not mean they will develop cancer. Genetic testing can open a “Pandora’s Box” of unanswerable questions. Everyone has a unique philosophy of life and belief system. Many decline genetic testing for personal reasons. Unfortunately, too many men and women at risk for genetic mutations are never offered genetic counselling. A recent study in the Journal of the American Medical Association found that many women with newly diagnosed breast cancer and at a high risk for genetic mutations are not offered genetic counseling.
- published: 26 Mar 2018
- views: 81425
3:52
Understanding BRCA Mutations and Risk
BRCA1 and BRCA2 are breast cancer gene mutations. When a mutation occurs, the gene doesn’t function properly, DNA errors don’t get repaired, and the risk of can...
BRCA1 and BRCA2 are breast cancer gene mutations. When a mutation occurs, the gene doesn’t function properly, DNA errors don’t get repaired, and the risk of cancer increases. A genetic counselor will review your family histories, discuss the testing process, and explain benefits as well as the risks of learning about a genetic mutation that may increase your cancer risk.
https://wn.com/Understanding_Brca_Mutations_And_Risk
BRCA1 and BRCA2 are breast cancer gene mutations. When a mutation occurs, the gene doesn’t function properly, DNA errors don’t get repaired, and the risk of cancer increases. A genetic counselor will review your family histories, discuss the testing process, and explain benefits as well as the risks of learning about a genetic mutation that may increase your cancer risk.
- published: 14 Apr 2017
- views: 33935
3:50
BRCA gene test questioned after unnecessary surgeries
Seven women in one family had major surgery after a widely used genetic test, taken by hundreds of thousands of people, showed a high cancer risk. One of them s...
Seven women in one family had major surgery after a widely used genetic test, taken by hundreds of thousands of people, showed a high cancer risk. One of them says she was left debilitated and unable to have more children. But, years later, the family has learned the results of that BRCA test might have been wrong. Jamie Yuccas reports.
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https://wn.com/Brca_Gene_Test_Questioned_After_Unnecessary_Surgeries
Seven women in one family had major surgery after a widely used genetic test, taken by hundreds of thousands of people, showed a high cancer risk. One of them says she was left debilitated and unable to have more children. But, years later, the family has learned the results of that BRCA test might have been wrong. Jamie Yuccas reports.
Watch "CBS This Morning" HERE: http://bit.ly/1T88yAR
Download the CBS News app on iOS HERE: https://apple.co/1tRNnUy
Download the CBS News app on Android HERE: https://bit.ly/1IcphuX
Like "CBS This Morning" on Facebook HERE: http://on.fb.me/1LhtdvI
Follow "CBS This Morning" on Twitter HERE: http://bit.ly/1Xj5W3p
Follow "CBS This Morning" on Instagram HERE: http://bit.ly/1Q7NGnY
Get new episodes of shows you love across devices the next day, stream local news live, and watch full seasons of CBS fan favorites anytime, anywhere with CBS All Access. Try it free! http://bit.ly/1OQA29B
Each weekday morning, "CBS This Morning" co-hosts Gayle King, Anthony Mason and Tony Dokoupil deliver two hours of original reporting, breaking news and top-level newsmaker interviews in an engaging and informative format that challenges the norm in network morning news programs. The broadcast has earned a prestigious Peabody Award, a Polk Award, four News & Documentary Emmys, three Daytime Emmys and the 2017 Edward R. Murrow Award for Best Newscast. The broadcast was also honored with an Alfred I. duPont-Columbia Award as part of CBS News division-wide coverage of the shootings at Sandy Hook Elementary School in Newtown, Connecticut. Check local listings for "CBS This Morning" broadcast times.
- published: 24 Dec 2019
- views: 6526
2:11
How Can I Prevent Cancer If I Have a BRCA Mutation? | Dana-Farber Cancer Institute
Dr. Garber, director of the Center for Cancer Genetics and Prevention at Dana-Farber, discusses ways to prevent cancer for those who carry a BRCA mutation.
Dr. Garber, director of the Center for Cancer Genetics and Prevention at Dana-Farber, discusses ways to prevent cancer for those who carry a BRCA mutation.
https://wn.com/How_Can_I_Prevent_Cancer_If_I_Have_A_Brca_Mutation_|_Dana_Farber_Cancer_Institute
Dr. Garber, director of the Center for Cancer Genetics and Prevention at Dana-Farber, discusses ways to prevent cancer for those who carry a BRCA mutation.
- published: 04 Dec 2015
- views: 611
2:54
Lisa: My Experience with BRCA Counseling and Testing
Lisa, age 40, talks about how her family history led her to get genetic counseling and testing for BRCA gene mutations. She describes the genetic testing experi...
Lisa, age 40, talks about how her family history led her to get genetic counseling and testing for BRCA gene mutations. She describes the genetic testing experience, and how it helped her understand her family history and manage her risk for breast cancer.
Comments on this video are allowed in accordance with our comment policy: http://www.cdc.gov/SocialMedia/Tools/CommentPolicy.html
This video can also be viewed at
http://www.cdc.gov/cancer/videos/breast/BringYourBrave/Lisa/MyExperienceCT/MyExperienceCT_lowRes.mp4
https://wn.com/Lisa_My_Experience_With_Brca_Counseling_And_Testing
Lisa, age 40, talks about how her family history led her to get genetic counseling and testing for BRCA gene mutations. She describes the genetic testing experience, and how it helped her understand her family history and manage her risk for breast cancer.
Comments on this video are allowed in accordance with our comment policy: http://www.cdc.gov/SocialMedia/Tools/CommentPolicy.html
This video can also be viewed at
http://www.cdc.gov/cancer/videos/breast/BringYourBrave/Lisa/MyExperienceCT/MyExperienceCT_lowRes.mp4
- published: 28 May 2015
- views: 35060