The génépy category comprises liqueurs often made by steeping génépy—or artemisia—flowers in neutral spirit. Forthave’s domestically produced Yellow is the distillery’s take on the aperitif, and is made with a natural wine instead of a higher-proof spirit. The more delicate approach is evident in its flavor, which allows the lighter floral tones to shine through. This bottling is at a lower proof and has a less-intense flavor profile, so enjoy it neat or in a spritz; in cocktails, try it in combination with higher-proof liqueurs. Other génépys, such as Dolin, which Stinchcomb uses as a direct substitute for green Chartreuse, work well, too.

According to Combier—the storied producer behind its namesake triple sec and a range of fruit liqueurs—the recipe for Élicser was discovered in the distiller’s almost-two-century-old archives. Though first released in the 19th century, the bottling recently came back into production, and its unique blend of spices—including cardamom, aloe, nutmeg and saffron (which is how it gets its yellow hue)—makes for a layered liqueur not unlike Chartreuse. Use in combination with a génépy to replicate yellow Chartreuse.

“Centum herbis” translates to “one hundred herbs” in Latin. The name is an apt description for a spirit combining gentian, herbal and floral flavors, including génépy. In online forums devoted to finding the best alternatives to Chartreuse, as well as on retailers’ websites, many have recommended this Italian liqueur as a close swap for the elusive French one.

This Chartreuse alternative comes from the makers of Straightaway Cocktails—a line of ready-to-drink Negronis, Margaritas and more. Made with hyssop, lemon balm and chamomile, this affordable option leans appropriately herbal and alpine. At Take Two, in Portland, Oregon, Flora Green is part of the Chartreuse-like house liqueur blend, which figures into the bar’s refreshing Green Day (gin, ginger, lime and a syrup of jalapeño, mint and cucumber).

With its green color and pitch as “our take on a European herbal liqueur,” Centerbe’s resemblance to green Chartreuse is evident. The producer recommends it in classics, such as the Bijou and Naked & Famous, that typically star the hard-to-find ingredient. With a higher proof than others on this list, its ABV is closer to Chartreuse’s, and it can be swapped in directly for the spirit where it typically plays a starring role, such as in a Chartreuse Swizzle. Or, as Bossy recommends, combine it in equal parts with génépy for more nuanced flavor.

Rhubarb, peppermint and chamomile star in this amaro from Piedmont-based producer Glep. The only amaro on this list, Grinta’s combination of botanicals yields an almost-medicinal liqueur, whose bracing quality makes it a worthy candidate to sub in for Chartreuse. As with nearly every bottling on this list, however, some experimentation will be required to dial in the ratio for any given cocktail.

At Bar Muse, Stinchcomb uses Strega in place of yellow Chartreuse. Compared with many aperitivo liqueurs, its flavor profile is predominately savory, rather than bittersweet, combining botanicals such as mint, saffron, star anise and white pepper. Try it in any cocktail where yellow Chartreuse stars, such as the Greenpoint or Naked & Famous.

While many of the liqueurs on this list are newer to the market, Centerba 72 is, like Chartreuse, centuries old. Based on a recipe from Benedictine friars in Abruzzo, this liqueur is made from herbs like oregano, pinesap and licorice from the Maiella mountains. Once a restorative sold via pharmacies, the liqueur became a product of a distillery in 1972, hence the name. With its high proof, Centerba 72 isn’t a direct substitute for Chartreuse in most applications, but it can fortify lower-ABV options in a blend, as it does at Take Two, or be served as a traditional digestivo.