CHE232 - Course Outline 2022

UNIVERSITY OF ESWATINI

FACULTY OF SCIENCE & ENGINEERING

DEPARTMENT OF CHEMISTRY
COURSE OUTLINE

Course Title Organic Reactions & Synthesis
Course Code CHE232
Year 2019/20 Semester 1st Semester 2nd Semester ü
Credits Lecture hours: 3 Practical hours: 0 Total credit: 3.0
Course type Core ü Required Elective General Education
Prerequisite N/A
course(s)
Course Instructor(s)
Name Office Phone E-mail
Dr T. Ndlovu S.1.4 76055082 [email protected]
Lecture Times
Check the most recent university timetable. The course has 3 credits hence 3 hours of lectures per week
Consultation Times
Working hours
Course Description
General introduction to the chemistry of the different classes of organic compounds: hydrocarbons, alkyl
halides, alcohols, aldehydes & ketones, benzene and its derivatives, carboxylic acids and their derivatives,
amines, phenols. Stereochemistry.
Basic aspects of orbitals and their role in covalent bonding; delocalization of electrons. Alkanes: structure,
nomenclature, isomerism, reactions. Introductory stereochemistry: enantiomers, diastereomers,
conformers, Fischer and Newman projections, specification of chirality, E/Z isomerism. Conformations of
cyclic compounds. Alkylhalides: SN1; SN2; E1; E2 reaction mechanisms. Free-radical reactions, organometallic
compounds. Chemistry of alkenes, alkynes, and dienes.
Broad Course Objective
Students will be equipped with the skills to propose synthetic routes for complex organic molecules.
Learning Outcomes
By the end of this course, students should be able to:
• Understand the differences between organic molecules and inorganic compounds.

• Recognize and understand the differences among different organic functional groups.
• Be able to name organic compounds and draw their structural formulas.
• Be able to predict the shape and hybridization of carbon-containing compounds.
• Be able to correlate the structure, shape, and polarity of an organic molecule with its physical
properties, such as boiling point and solubility.
• Be able to predict the products of some simple organic reactions.
Course content
Alkanes
• Covalent bonding, sp3 hybridization, Isomers, Structural isomers, drawing organic molecules,
Hydrocarbons, Conformations of alkanes, Structural isomers, Rules of IUPAC nomenclature,
Nomenclature of alkanes, Cycloalkanes and Geometric isomers, Physical properties of alkanes,
Reactions including combustion, chain reactions
Unsaturated Hydrocarbons – Alkenes
• Nomenclature of alkenes, Hybridization in alkenes, Geometric isomers, Physical properties of

alkenes, Addition reactions: Halogenation, Hydrogenation, Addition of acids, Hydration,
Markonikov’s rule, Addition polymers.
• Alkyne nomenclature, Alkyne reactions, Hybridization in alkynes
• Aromatic compounds, Resonance structures in benzene, Nomenclature of aromatic compounds,
Physical and chemical properties of aromatic compounds
Stereochemistry
• Definition of chirality; Optical activity, enantiomers, meso compounds, diastereoisomers; Define

configuration, separation of enantiomers, R & S. Configuration.
Alkyl Halides
• Methods of preparation from alkanes, alkenes and alcohols;

• Substitution reactions. Mechanisms of SNI and SN2 reactions
• Elimination reactions – E1 and E2 reactions
• The Grignard Reagents – Preparation and reactions to CO2, aldehydes, Ketones.
Alcohols, Phenols, and Ethers.
• Nomenclature and classification of alcohols, Physical properties and hydrogen bonding, Boiling
points, Dehydration reactions that produce alkenes, Dehydrations that produce ethers, Oxidation of
primary, secondary, and tertiary alcohols, Multi-step reactions,
• Phenols; A brief introduction to the chemistry of phenols. Acidity compared to alcohols and
carboxylic acid.
• Nomenclature of ethers, Properties of ethers, Polyfunctional compounds, preparation & reactions
of ethers.
Aldehydes and Ketones.

• The carbonyl group, Nomenclature of aldehydes & ketones, Physical properties of aldehydes and
ketones, Common aldehydes and ketones, Oxidation of aldehydes and ketones, Hydrogenation,
Addition of alcohols, Acetals, hemiacetals, ketals, and hemiketals. Hydrolysis of acetals and ketals.
Carboxylic Acids and Esters.
• Nomenclature of carboxylic acids, Physical properties of carboxylic acids, Acidity of carboxylic acids,
Carboxylate salts, Reactions of carboxylic acids,
• Nomenclature of esters, Synthesis of esters, Hydrolysis and saponification of esters, Triglycerides
and soaps.
Amines and Amides.
• Classification and nomenclature of amines, Physical properties of amines, Basicity of amines, Alkyl
ammonium salts, Quaternary ammonium salts, Reactions of amines, Nomenclature of amides,
Physical properties of amides, Formation of amides, Reactions of amides.
Teaching method and activities (Delivery Mode)

Blended learning including Face-to-face and online platforms using PowerPoint slides. Students will be
expected to actively participate in class and the slides will have practice questions to be done either in class
or off class. During the time where face-to-face is not possible, online teaching will be used. PowerPoint
slides with voice overs will be posted on Moodle.
Assessment Policy
The normal assessment policy for the university will be employed. This will be adjusted as advised by
UNESWA. For online purposes, more assessments may be given which will weigh differently 9depending
on type of assessment). The final CA will be calculated based on the assessments given and their weighting
will be shared at the end of the semester.
Assessment method Description Weight (%)
I. Continuous Assessment 2 tests will be given, each covering a

selection of topics which have already been (40%)
covered in class.
II. Final Exam A 3-hour exam with 2 sections. A

compulsory Section A, designed to test basic
understanding of all the topics and Section B (60%)
which will test deeper understanding of
specific topics.
Policy on Tests Dates and Missed Tests

Test dates will be announced at the beginning of the semester (where possible) after all students have
registered. Attendance for tests is compulsory. Failure to attend a test will result in a mark of zero (0) for
the test. Students who miss a test due to illness, must submit a doctor’s certificate through the Dean of
Student Affairs office. Such cases will be considered on their merits. A medical certificate does not
guarantee that absence will be excused.
Policy on Academic Dishonesty

Academic dishonesty (“cheating”) is taken seriously by the University and will not be tolerated. Penalties
for academic misconduct in assessment activities including (but not limited to) tests, assignments, practical
reports, and projects are highlighted in the University Academic General Regulations 011.50 -- 011.90 &
012.45 -- 012.46.
Prescribed/Recommended Books
Prescribed:
1. Organic Chemistry 9th edition, Leroy G. Wade, Jr and Jan William Simek, Pearson Education
Limited, 2017
2. Organic Chemistry 11th edition, Solomons, Fryhle and Snyder,
Further reading:
1. Organic Chemistry by Jonathan Clayden, Nick Greeves, Stuart Warren. Oxford University
Press. 2nd Edition, 2012.
2. Organic Chemistry by David R. Klein 3rd edition
3. Organic Chemistry 9th edition, John McMurry, Cengage Learning, 2016

CHE232 - Course Outline 2022

Uploaded by

Copyright:

Available Formats

CHE232 - Course Outline 2022

Uploaded by

Document Information

Original Description:

Original Title

Copyright

Available Formats

Share this document

Share or Embed Document

Sharing Options

Did you find this document useful?

Is this content inappropriate?

Copyright:

Available Formats

CHE232 - Course Outline 2022

Uploaded by

Copyright:

Available Formats

UNIVERSITY OF ESWATINI

FACULTY OF SCIENCE & ENGINEERING

Course Title Organic Reactions & Synthesis

Course Code CHE232

Year 2019/20 Semester 1st Semester 2nd Semester ü

Credits Lecture hours: 3 Practical hours: 0 Total credit: 3.0

Course type Core ü Required Elective General Education

Name Office Phone E-mail

Dr T. Ndlovu S.1.4 76055082 [email protected]

Broad Course Objective

• Understand the differences between organic molecules and inorganic compounds.

• Nomenclature of alkenes, Hybridization in alkenes, Geometric isomers, Physical properties of

• Definition of chirality; Optical activity, enantiomers, meso compounds, diastereoisomers; Define

• Methods of preparation from alkanes, alkenes and alcohols;

Aldehydes and Ketones.

Carboxylic Acids and Esters.

Amines and Amides.

Teaching method and activities (Delivery Mode)

Assessment method Description Weight (%)

I. Continuous Assessment 2 tests will be given, each covering a

II. Final Exam A 3-hour exam with 2 sections. A

Policy on Tests Dates and Missed Tests

Policy on Academic Dishonesty

You might also like