-
Rocket ship (disambiguation) | Wikipedia audio article
This is an audio version of the Wikipedia Article:
https://en.wikipedia.org/wiki/Rocketship_(disambiguation)
00:00:21 Music
00:00:34 Songs
Listening is a more natural way of learning, when compared to reading. Written language only began at around 3200 BC, but spoken language has existed long ago.
Learning by listening is a great way to:
- increases imagination and understanding
- improves your listening skills
- improves your own spoken accent
- learn while on the move
- reduce eye strain
Now learn the vast amount of general knowledge available on Wikipedia through audio (audio article). You could even learn subconsciously by playing the audio while you are sleeping! If you are planning to listen a lot, you could try using a bone conduction headphone, or a standard ...
published: 02 Jun 2019
-
Top 10 Post Apocalyptic TV Series
If you want to know how civilization would look once it is crumbled you should definitely watch our picks for the best Post Apocalyptic tv shows.
Discover the best…
📹 YouTube tool: https://www.tubebuddy.com/communitv
We missed your favorite Post-Apocalyptic TV Series? Let us know in the comments!
Follow us on...
Instagram: http://bit.ly/2rnljTB
Facebook: http://bit.ly/2PbYxGn
Movies in this Ranking:
10. Falling Skies (2011–2015): (00:26)
9. Colony (2016–2018): (01:16)
8. The Last Ship (2014–2018): (02:07)
7. Station Eleven (2021-2022): (02:56)
6. See (2019- ): (03:42)
5. The 100 (2014–2020): (04:29)
4. Sweet Tooth (2021- ): (05:17)
3. Jericho (2006–2008): (06:06)
2. Into the Badlands (2015–2019): (06:58)
1. The Walking Dead (2010–2022): (08:45)
You want to work with us?
For ...
published: 12 Jul 2022
-
Towada (disambiguation)
Towada is a city in Aomori Prefecture, Japan.
Towada may also refer to:
Lake Towada, a crater lake on the border between Aomori and Akita prefectures, Japan
Towada-class replenishment ship, a series of ships of the Japan Maritime Self-Defense Force
JS Towada, the lead ship of the class
Source: https://en.wikipedia.org/wiki/Towada_(disambiguation)
Created with WikipediaReaderReborn (c) WikipediaReader
published: 07 May 2021
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Blue Riband (disambiguation) Top # 10 Facts
Blue Riband (disambiguation) Top # 10 Facts
published: 02 Nov 2015
-
Repo Men (2010) - Organ Collecting Scene (1/10) | Movieclips
Repo Men - Organ Collecting: Remy (Jude Law) repossesses a client's organs.
BUY THE MOVIE: https://www.fandangonow.com/details/movie/repo-men-2010/1MV5f3db01ab424e0f494370a409b583a57?cmp=Movieclips_YT_Description
Watch the best Repo Men scenes & clips:
https://www.youtube.com/playlist?list=PLZbXA4lyCtqpYQy3BetiL1I0SPIc9oLdb
FILM DESCRIPTION:
In the future, medical technology has advanced to the point where people can buy artificial organs to extend their lives. But if they default on payments, an organization known as the Union sends agents to repossess the organs. Remy (Jude Law) is one of the best agents in the business, but when he becomes the recipient of an artificial heart, he finds himself in the same dire straits as his many victims. With his former partner (Forest Whitaker) in h...
published: 16 Oct 2020
-
Rate Lord x fit ( Sonic.exe animation)
published: 06 Nov 2023
-
Top 10 Worst TV Shows of All Time
Boy, there sure is some terrible television in the world…. Join http://www.WatchMojo.com as we count down our picks for theTop 10 Worst TV Shows of All Time. Subscribe►►http://www.youtube.com/subscription_center?add_user=watchmojo Facebook►►http://www.Facebook.com/WatchMojo. Twitter►►http://www.Twitter.com/WatchMojo Instagram►►http://instagram.com/watchmojo Suggestion Tool►►http://www.WatchMojo.com/suggest Channel Page►►http://www.youtube.com/watchmojo
For this list, we'll be scouring TV's lengthy history in search of the programs that are universally viewed as lacking in quality.
Special thanks to our users Liza Davydzenkava, SuperSaiyanKirby100, DonovanTPS, Jerome Magajes, Aeryk Marcellus Bacon, TylerKienzlen@gmail., sarahjessicaparkerth, mac121mr0, Brody Nicholas Eiffel Jay, jhwoe6, P...
published: 19 Jan 2016
-
Marine engineering (disambiguation) | Wikipedia audio article
This is an audio version of the Wikipedia Article:
https://en.wikipedia.org/wiki/Marine_engineering
00:00:41 1 History
00:01:05 1.1 Marine steam engineering
00:01:43 1.1.1 Paddle wheel ships
00:02:33 1.2 Offshore oil rigs
00:02:57 2 Marine engineering specialties
00:03:08 2.1 Naval architect
00:03:24 2.2 Mechanical engineering
00:04:00 2.3 Oceanographic engineering
00:04:27 2.4 Offshore engineering
00:04:48 3 Challenges specific to marine engineering
00:04:59 3.1 Hydrodynamic loading
00:05:23 3.2 Stability
00:06:11 3.3 Corrosion
00:07:07 3.4 Anti-fouling
00:08:32 3.5 Pollution control
00:08:41 3.5.1 Sulfur emission
00:09:31 3.5.2 Oil and water discharge
00:10:30 3.6 Cavitation
00:11:37 4 Career
00:11:59 5 Industry growth
00:12:45 6 Education
00:13:14 6.1 Professional institutions
00:...
published: 07 Jul 2019
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Herschel Island (disambiguation)
Herschel Island may refer to:Herschel Island, an island in the Arctic's Beaufort Sea
Herschel Island (Chile), an Chilean island near the Drake Passage
Herschel Island (ship, 1956), see Boats of the Mackenzie River watershed
Source: https://en.wikipedia.org/wiki/Herschel_Island_(disambiguation)
Created with WikipediaReaderReborn (c) WikipediaReader
published: 20 Apr 2022
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Prize (disambiguation)
Prize,(disambiguation)
A,prize,is,an,award,received,for,merit
Prize,may,also,refer,to:
Media
The,Prize,novel,,1962,novel,by,Irving,Wallace
The,Prize,1963,film,,1963,film,based,on,the,novel
The,Prize,2011,film,,a,2011,film
The,Prize:,The,Epic,Quest,for,Oil,,Money,,and,Power,,1991,book,by,Daniel,Yergin
Other
Prize,law,,captured,or,recovered,vessel
Prize,marketing,,promotional,item,usually,a,toy,or,other,small,object,of,nominal,value,included,free,in,a,retail,product
Prize,,California,,former,settlement
Prize,money,,paid,to,naval,personnel,for,the,successful,capture,of,a,ship
HMS,Prize,,UK,Royal,Navy,ship
See,also
Price,disambiguation
This,disambiguation,page,lists,articles,associated,with,the,title,Prize
If,an,internal,link,led,you,here,,you,may,wish,to,change,the,link,to,point,directly,to,t...
published: 26 Jun 2019
1:19
Rocket ship (disambiguation) | Wikipedia audio article
This is an audio version of the Wikipedia Article:
https://en.wikipedia.org/wiki/Rocketship_(disambiguation)
00:00:21 Music
00:00:34 Songs
Listening...
This is an audio version of the Wikipedia Article:
https://en.wikipedia.org/wiki/Rocketship_(disambiguation)
00:00:21 Music
00:00:34 Songs
Listening is a more natural way of learning, when compared to reading. Written language only began at around 3200 BC, but spoken language has existed long ago.
Learning by listening is a great way to:
- increases imagination and understanding
- improves your listening skills
- improves your own spoken accent
- learn while on the move
- reduce eye strain
Now learn the vast amount of general knowledge available on Wikipedia through audio (audio article). You could even learn subconsciously by playing the audio while you are sleeping! If you are planning to listen a lot, you could try using a bone conduction headphone, or a standard speaker instead of an earphone.
Listen on Google Assistant through Extra Audio:
https://assistant.google.com/services/invoke/uid/0000001a130b3f91
Other Wikipedia audio articles at:
https://www.youtube.com/results?search_query=wikipedia+tts
Upload your own Wikipedia articles through:
https://github.com/nodef/wikipedia-tts
Speaking Rate: 0.9444559585120023
Voice name: en-AU-Wavenet-C
"I cannot teach anybody anything, I can only make them think."
- Socrates
SUMMARY
=======
Rocketship, Rocket Ship, or Rocket ship may refer to:
A space vehicle
Rocket Ship, the original title of a 1936 feature film derived from the Flash Gordon serial
Landing Craft Tank (Rocket), military ships armed with rockets
Missile cruiser, military ships armed with missiles
https://wn.com/Rocket_Ship_(Disambiguation)_|_Wikipedia_Audio_Article
This is an audio version of the Wikipedia Article:
https://en.wikipedia.org/wiki/Rocketship_(disambiguation)
00:00:21 Music
00:00:34 Songs
Listening is a more natural way of learning, when compared to reading. Written language only began at around 3200 BC, but spoken language has existed long ago.
Learning by listening is a great way to:
- increases imagination and understanding
- improves your listening skills
- improves your own spoken accent
- learn while on the move
- reduce eye strain
Now learn the vast amount of general knowledge available on Wikipedia through audio (audio article). You could even learn subconsciously by playing the audio while you are sleeping! If you are planning to listen a lot, you could try using a bone conduction headphone, or a standard speaker instead of an earphone.
Listen on Google Assistant through Extra Audio:
https://assistant.google.com/services/invoke/uid/0000001a130b3f91
Other Wikipedia audio articles at:
https://www.youtube.com/results?search_query=wikipedia+tts
Upload your own Wikipedia articles through:
https://github.com/nodef/wikipedia-tts
Speaking Rate: 0.9444559585120023
Voice name: en-AU-Wavenet-C
"I cannot teach anybody anything, I can only make them think."
- Socrates
SUMMARY
=======
Rocketship, Rocket Ship, or Rocket ship may refer to:
A space vehicle
Rocket Ship, the original title of a 1936 feature film derived from the Flash Gordon serial
Landing Craft Tank (Rocket), military ships armed with rockets
Missile cruiser, military ships armed with missiles
- published: 02 Jun 2019
- views: 2
9:14
Top 10 Post Apocalyptic TV Series
If you want to know how civilization would look once it is crumbled you should definitely watch our picks for the best Post Apocalyptic tv shows.
Discover the ...
If you want to know how civilization would look once it is crumbled you should definitely watch our picks for the best Post Apocalyptic tv shows.
Discover the best…
📹 YouTube tool: https://www.tubebuddy.com/communitv
We missed your favorite Post-Apocalyptic TV Series? Let us know in the comments!
Follow us on...
Instagram: http://bit.ly/2rnljTB
Facebook: http://bit.ly/2PbYxGn
Movies in this Ranking:
10. Falling Skies (2011–2015): (00:26)
9. Colony (2016–2018): (01:16)
8. The Last Ship (2014–2018): (02:07)
7. Station Eleven (2021-2022): (02:56)
6. See (2019- ): (03:42)
5. The 100 (2014–2020): (04:29)
4. Sweet Tooth (2021- ): (05:17)
3. Jericho (2006–2008): (06:06)
2. Into the Badlands (2015–2019): (06:58)
1. The Walking Dead (2010–2022): (08:45)
You want to work with us?
For collaboration requests please contact us via…
Mail:
[email protected]
Music: www.bensound.com
https://wn.com/Top_10_Post_Apocalyptic_Tv_Series
If you want to know how civilization would look once it is crumbled you should definitely watch our picks for the best Post Apocalyptic tv shows.
Discover the best…
📹 YouTube tool: https://www.tubebuddy.com/communitv
We missed your favorite Post-Apocalyptic TV Series? Let us know in the comments!
Follow us on...
Instagram: http://bit.ly/2rnljTB
Facebook: http://bit.ly/2PbYxGn
Movies in this Ranking:
10. Falling Skies (2011–2015): (00:26)
9. Colony (2016–2018): (01:16)
8. The Last Ship (2014–2018): (02:07)
7. Station Eleven (2021-2022): (02:56)
6. See (2019- ): (03:42)
5. The 100 (2014–2020): (04:29)
4. Sweet Tooth (2021- ): (05:17)
3. Jericho (2006–2008): (06:06)
2. Into the Badlands (2015–2019): (06:58)
1. The Walking Dead (2010–2022): (08:45)
You want to work with us?
For collaboration requests please contact us via…
Mail:
[email protected]
Music: www.bensound.com
- published: 12 Jul 2022
- views: 1666290
0:28
Towada (disambiguation)
Towada is a city in Aomori Prefecture, Japan.
Towada may also refer to:
Lake Towada, a crater lake on the border between Aomori and Akita prefectures, Japan
To...
Towada is a city in Aomori Prefecture, Japan.
Towada may also refer to:
Lake Towada, a crater lake on the border between Aomori and Akita prefectures, Japan
Towada-class replenishment ship, a series of ships of the Japan Maritime Self-Defense Force
JS Towada, the lead ship of the class
Source: https://en.wikipedia.org/wiki/Towada_(disambiguation)
Created with WikipediaReaderReborn (c) WikipediaReader
https://wn.com/Towada_(Disambiguation)
Towada is a city in Aomori Prefecture, Japan.
Towada may also refer to:
Lake Towada, a crater lake on the border between Aomori and Akita prefectures, Japan
Towada-class replenishment ship, a series of ships of the Japan Maritime Self-Defense Force
JS Towada, the lead ship of the class
Source: https://en.wikipedia.org/wiki/Towada_(disambiguation)
Created with WikipediaReaderReborn (c) WikipediaReader
- published: 07 May 2021
- views: 1
3:10
Repo Men (2010) - Organ Collecting Scene (1/10) | Movieclips
Repo Men - Organ Collecting: Remy (Jude Law) repossesses a client's organs.
BUY THE MOVIE: https://www.fandangonow.com/details/movie/repo-men-2010/1MV5f3db01ab4...
Repo Men - Organ Collecting: Remy (Jude Law) repossesses a client's organs.
BUY THE MOVIE: https://www.fandangonow.com/details/movie/repo-men-2010/1MV5f3db01ab424e0f494370a409b583a57?cmp=Movieclips_YT_Description
Watch the best Repo Men scenes & clips:
https://www.youtube.com/playlist?list=PLZbXA4lyCtqpYQy3BetiL1I0SPIc9oLdb
FILM DESCRIPTION:
In the future, medical technology has advanced to the point where people can buy artificial organs to extend their lives. But if they default on payments, an organization known as the Union sends agents to repossess the organs. Remy (Jude Law) is one of the best agents in the business, but when he becomes the recipient of an artificial heart, he finds himself in the same dire straits as his many victims. With his former partner (Forest Whitaker) in hot pursuit, Remy runs for his life.
CREDITS:
TM & © Universal (2010)
Cast: Jude Law
Screenwriter: Eric Garcia, Garrett Lerner
Director: Miguel Sapochnik
Watch More:
► Fresh New Clips: http://bit.ly/2taDWqW
► Classic Trailers: http://bit.ly/2qTCxHF
► Hot New Trailers: http://bit.ly/2qThrsF
► Clips From Movies Coming Soon: http://bit.ly/2FrP8VL
► Indie Movie Clips: http://bit.ly/2qTZMRE
► Deleted Scenes: http://bit.ly/2ARbLPJ
► Bloopers: http://bit.ly/2qYmBnc
► Celebrity Interviews: http://bit.ly/2D4tzw4
Fuel Your Movie Obsession:
► Subscribe to MOVIECLIPS: http://bit.ly/2CZa490
► Watch Movieclips ORIGINALS: http://bit.ly/2D3sipV
► Like us on FACEBOOK: http://bit.ly/2DikvkY
► Follow us on TWITTER: http://bit.ly/2mgkaHb
► Follow us on INSTAGRAM: http://bit.ly/2mg0VNU
The MOVIECLIPS channel is the largest collection of licensed movie clips on the web. Here you will find unforgettable moments, scenes, and lines from all your favorite films. Made by movie fans, for movie fans.
https://wn.com/Repo_Men_(2010)_Organ_Collecting_Scene_(1_10)_|_Movieclips
Repo Men - Organ Collecting: Remy (Jude Law) repossesses a client's organs.
BUY THE MOVIE: https://www.fandangonow.com/details/movie/repo-men-2010/1MV5f3db01ab424e0f494370a409b583a57?cmp=Movieclips_YT_Description
Watch the best Repo Men scenes & clips:
https://www.youtube.com/playlist?list=PLZbXA4lyCtqpYQy3BetiL1I0SPIc9oLdb
FILM DESCRIPTION:
In the future, medical technology has advanced to the point where people can buy artificial organs to extend their lives. But if they default on payments, an organization known as the Union sends agents to repossess the organs. Remy (Jude Law) is one of the best agents in the business, but when he becomes the recipient of an artificial heart, he finds himself in the same dire straits as his many victims. With his former partner (Forest Whitaker) in hot pursuit, Remy runs for his life.
CREDITS:
TM & © Universal (2010)
Cast: Jude Law
Screenwriter: Eric Garcia, Garrett Lerner
Director: Miguel Sapochnik
Watch More:
► Fresh New Clips: http://bit.ly/2taDWqW
► Classic Trailers: http://bit.ly/2qTCxHF
► Hot New Trailers: http://bit.ly/2qThrsF
► Clips From Movies Coming Soon: http://bit.ly/2FrP8VL
► Indie Movie Clips: http://bit.ly/2qTZMRE
► Deleted Scenes: http://bit.ly/2ARbLPJ
► Bloopers: http://bit.ly/2qYmBnc
► Celebrity Interviews: http://bit.ly/2D4tzw4
Fuel Your Movie Obsession:
► Subscribe to MOVIECLIPS: http://bit.ly/2CZa490
► Watch Movieclips ORIGINALS: http://bit.ly/2D3sipV
► Like us on FACEBOOK: http://bit.ly/2DikvkY
► Follow us on TWITTER: http://bit.ly/2mgkaHb
► Follow us on INSTAGRAM: http://bit.ly/2mg0VNU
The MOVIECLIPS channel is the largest collection of licensed movie clips on the web. Here you will find unforgettable moments, scenes, and lines from all your favorite films. Made by movie fans, for movie fans.
- published: 16 Oct 2020
- views: 128888
13:58
Top 10 Worst TV Shows of All Time
Boy, there sure is some terrible television in the world…. Join http://www.WatchMojo.com as we count down our picks for theTop 10 Worst TV Shows of All Time. Su...
Boy, there sure is some terrible television in the world…. Join http://www.WatchMojo.com as we count down our picks for theTop 10 Worst TV Shows of All Time. Subscribe►►http://www.youtube.com/subscription_center?add_user=watchmojo Facebook►►http://www.Facebook.com/WatchMojo. Twitter►►http://www.Twitter.com/WatchMojo Instagram►►http://instagram.com/watchmojo Suggestion Tool►►http://www.WatchMojo.com/suggest Channel Page►►http://www.youtube.com/watchmojo
For this list, we'll be scouring TV's lengthy history in search of the programs that are universally viewed as lacking in quality.
Special thanks to our users Liza Davydzenkava, SuperSaiyanKirby100, DonovanTPS, Jerome Magajes, Aeryk Marcellus Bacon, TylerKienzlen@gmail., sarahjessicaparkerth, mac121mr0, Brody Nicholas Eiffel Jay, jhwoe6, PenName102, Francis FNT, MineNotCraft, Johnny B. Goode, Freightliner66Produc, Aidansreviews, bruce wayne, raccoon, Red Alejandro andSuperMonkeyGyrados for submitting the idea on our Interactive Suggestion Tool at http://www.WatchMojo.com/suggest
Check out the voting page here,
http://watchmojo.com/suggest/Top+10+Bad+Shows+That+Should+Stay+Dead
Want a WatchMojo cup, mug, t-shirts, pen, sticker and even a water bottle? Get them all when you order your MojoBox gift set here:
http://watchmojo.com/store/
WatchMojo is a leading producer of reference online video content, covering the People, Places and Trends you care about.
We update DAILY with 4-5 Top 10 lists, Origins, Biographies, Versus clips on movies, video games, music, pop culture and more!
https://wn.com/Top_10_Worst_Tv_Shows_Of_All_Time
Boy, there sure is some terrible television in the world…. Join http://www.WatchMojo.com as we count down our picks for theTop 10 Worst TV Shows of All Time. Subscribe►►http://www.youtube.com/subscription_center?add_user=watchmojo Facebook►►http://www.Facebook.com/WatchMojo. Twitter►►http://www.Twitter.com/WatchMojo Instagram►►http://instagram.com/watchmojo Suggestion Tool►►http://www.WatchMojo.com/suggest Channel Page►►http://www.youtube.com/watchmojo
For this list, we'll be scouring TV's lengthy history in search of the programs that are universally viewed as lacking in quality.
Special thanks to our users Liza Davydzenkava, SuperSaiyanKirby100, DonovanTPS, Jerome Magajes, Aeryk Marcellus Bacon, TylerKienzlen@gmail., sarahjessicaparkerth, mac121mr0, Brody Nicholas Eiffel Jay, jhwoe6, PenName102, Francis FNT, MineNotCraft, Johnny B. Goode, Freightliner66Produc, Aidansreviews, bruce wayne, raccoon, Red Alejandro andSuperMonkeyGyrados for submitting the idea on our Interactive Suggestion Tool at http://www.WatchMojo.com/suggest
Check out the voting page here,
http://watchmojo.com/suggest/Top+10+Bad+Shows+That+Should+Stay+Dead
Want a WatchMojo cup, mug, t-shirts, pen, sticker and even a water bottle? Get them all when you order your MojoBox gift set here:
http://watchmojo.com/store/
WatchMojo is a leading producer of reference online video content, covering the People, Places and Trends you care about.
We update DAILY with 4-5 Top 10 lists, Origins, Biographies, Versus clips on movies, video games, music, pop culture and more!
- published: 19 Jan 2016
- views: 2635722
14:13
Marine engineering (disambiguation) | Wikipedia audio article
This is an audio version of the Wikipedia Article:
https://en.wikipedia.org/wiki/Marine_engineering
00:00:41 1 History
00:01:05 1.1 Marine steam engineeri...
This is an audio version of the Wikipedia Article:
https://en.wikipedia.org/wiki/Marine_engineering
00:00:41 1 History
00:01:05 1.1 Marine steam engineering
00:01:43 1.1.1 Paddle wheel ships
00:02:33 1.2 Offshore oil rigs
00:02:57 2 Marine engineering specialties
00:03:08 2.1 Naval architect
00:03:24 2.2 Mechanical engineering
00:04:00 2.3 Oceanographic engineering
00:04:27 2.4 Offshore engineering
00:04:48 3 Challenges specific to marine engineering
00:04:59 3.1 Hydrodynamic loading
00:05:23 3.2 Stability
00:06:11 3.3 Corrosion
00:07:07 3.4 Anti-fouling
00:08:32 3.5 Pollution control
00:08:41 3.5.1 Sulfur emission
00:09:31 3.5.2 Oil and water discharge
00:10:30 3.6 Cavitation
00:11:37 4 Career
00:11:59 5 Industry growth
00:12:45 6 Education
00:13:14 6.1 Professional institutions
00:13:49 7 See also
Listening is a more natural way of learning, when compared to reading. Written language only began at around 3200 BC, but spoken language has existed long ago.
Learning by listening is a great way to:
- increases imagination and understanding
- improves your listening skills
- improves your own spoken accent
- learn while on the move
- reduce eye strain
Now learn the vast amount of general knowledge available on Wikipedia through audio (audio article). You could even learn subconsciously by playing the audio while you are sleeping! If you are planning to listen a lot, you could try using a bone conduction headphone, or a standard speaker instead of an earphone.
Listen on Google Assistant through Extra Audio:
https://assistant.google.com/services/invoke/uid/0000001a130b3f91
Other Wikipedia audio articles at:
https://www.youtube.com/results?search_query=wikipedia+tts
Upload your own Wikipedia articles through:
https://github.com/nodef/wikipedia-tts
Speaking Rate: 0.9476888533908164
Voice name: en-GB-Wavenet-A
"I cannot teach anybody anything, I can only make them think."
- Socrates
SUMMARY
=======
Marine engineering includes the engineering of boats, ships, oil rigs and any other marine vessel or structure, as well as oceanographic engineering or ocean engineering. Specifically, marine engineering is the discipline of applying engineering sciences, including mechanical engineering, electrical engineering, electronic engineering, and computer science, to the development, design, operation and maintenance of watercraft propulsion and on-board systems and oceanographic technology. It includes but is not limited to power and propulsion plants, machinery, piping, automation and control systems for marine vehicles of any kind, such as surface ships and submarines.
https://wn.com/Marine_Engineering_(Disambiguation)_|_Wikipedia_Audio_Article
This is an audio version of the Wikipedia Article:
https://en.wikipedia.org/wiki/Marine_engineering
00:00:41 1 History
00:01:05 1.1 Marine steam engineering
00:01:43 1.1.1 Paddle wheel ships
00:02:33 1.2 Offshore oil rigs
00:02:57 2 Marine engineering specialties
00:03:08 2.1 Naval architect
00:03:24 2.2 Mechanical engineering
00:04:00 2.3 Oceanographic engineering
00:04:27 2.4 Offshore engineering
00:04:48 3 Challenges specific to marine engineering
00:04:59 3.1 Hydrodynamic loading
00:05:23 3.2 Stability
00:06:11 3.3 Corrosion
00:07:07 3.4 Anti-fouling
00:08:32 3.5 Pollution control
00:08:41 3.5.1 Sulfur emission
00:09:31 3.5.2 Oil and water discharge
00:10:30 3.6 Cavitation
00:11:37 4 Career
00:11:59 5 Industry growth
00:12:45 6 Education
00:13:14 6.1 Professional institutions
00:13:49 7 See also
Listening is a more natural way of learning, when compared to reading. Written language only began at around 3200 BC, but spoken language has existed long ago.
Learning by listening is a great way to:
- increases imagination and understanding
- improves your listening skills
- improves your own spoken accent
- learn while on the move
- reduce eye strain
Now learn the vast amount of general knowledge available on Wikipedia through audio (audio article). You could even learn subconsciously by playing the audio while you are sleeping! If you are planning to listen a lot, you could try using a bone conduction headphone, or a standard speaker instead of an earphone.
Listen on Google Assistant through Extra Audio:
https://assistant.google.com/services/invoke/uid/0000001a130b3f91
Other Wikipedia audio articles at:
https://www.youtube.com/results?search_query=wikipedia+tts
Upload your own Wikipedia articles through:
https://github.com/nodef/wikipedia-tts
Speaking Rate: 0.9476888533908164
Voice name: en-GB-Wavenet-A
"I cannot teach anybody anything, I can only make them think."
- Socrates
SUMMARY
=======
Marine engineering includes the engineering of boats, ships, oil rigs and any other marine vessel or structure, as well as oceanographic engineering or ocean engineering. Specifically, marine engineering is the discipline of applying engineering sciences, including mechanical engineering, electrical engineering, electronic engineering, and computer science, to the development, design, operation and maintenance of watercraft propulsion and on-board systems and oceanographic technology. It includes but is not limited to power and propulsion plants, machinery, piping, automation and control systems for marine vehicles of any kind, such as surface ships and submarines.
- published: 07 Jul 2019
- views: 11
0:23
Herschel Island (disambiguation)
Herschel Island may refer to:Herschel Island, an island in the Arctic's Beaufort Sea
Herschel Island (Chile), an Chilean island near the Drake Passage
Herschel ...
Herschel Island may refer to:Herschel Island, an island in the Arctic's Beaufort Sea
Herschel Island (Chile), an Chilean island near the Drake Passage
Herschel Island (ship, 1956), see Boats of the Mackenzie River watershed
Source: https://en.wikipedia.org/wiki/Herschel_Island_(disambiguation)
Created with WikipediaReaderReborn (c) WikipediaReader
https://wn.com/Herschel_Island_(Disambiguation)
Herschel Island may refer to:Herschel Island, an island in the Arctic's Beaufort Sea
Herschel Island (Chile), an Chilean island near the Drake Passage
Herschel Island (ship, 1956), see Boats of the Mackenzie River watershed
Source: https://en.wikipedia.org/wiki/Herschel_Island_(disambiguation)
Created with WikipediaReaderReborn (c) WikipediaReader
- published: 20 Apr 2022
- views: 2
1:06
Prize (disambiguation)
Prize,(disambiguation)
A,prize,is,an,award,received,for,merit
Prize,may,also,refer,to:
Media
The,Prize,novel,,1962,novel,by,Irving,Wallace
The,Prize,1963,film,,...
Prize,(disambiguation)
A,prize,is,an,award,received,for,merit
Prize,may,also,refer,to:
Media
The,Prize,novel,,1962,novel,by,Irving,Wallace
The,Prize,1963,film,,1963,film,based,on,the,novel
The,Prize,2011,film,,a,2011,film
The,Prize:,The,Epic,Quest,for,Oil,,Money,,and,Power,,1991,book,by,Daniel,Yergin
Other
Prize,law,,captured,or,recovered,vessel
Prize,marketing,,promotional,item,usually,a,toy,or,other,small,object,of,nominal,value,included,free,in,a,retail,product
Prize,,California,,former,settlement
Prize,money,,paid,to,naval,personnel,for,the,successful,capture,of,a,ship
HMS,Prize,,UK,Royal,Navy,ship
See,also
Price,disambiguation
This,disambiguation,page,lists,articles,associated,with,the,title,Prize
If,an,internal,link,led,you,here,,you,may,wish,to,change,the,link,to,point,directly,to,the,intended,article
prize,bond,,prize,bond,schedule,2018,,prize,bond,results,,prize,bond,draw,2018,Prize,(disambiguation)
,
https://wn.com/Prize_(Disambiguation)
Prize,(disambiguation)
A,prize,is,an,award,received,for,merit
Prize,may,also,refer,to:
Media
The,Prize,novel,,1962,novel,by,Irving,Wallace
The,Prize,1963,film,,1963,film,based,on,the,novel
The,Prize,2011,film,,a,2011,film
The,Prize:,The,Epic,Quest,for,Oil,,Money,,and,Power,,1991,book,by,Daniel,Yergin
Other
Prize,law,,captured,or,recovered,vessel
Prize,marketing,,promotional,item,usually,a,toy,or,other,small,object,of,nominal,value,included,free,in,a,retail,product
Prize,,California,,former,settlement
Prize,money,,paid,to,naval,personnel,for,the,successful,capture,of,a,ship
HMS,Prize,,UK,Royal,Navy,ship
See,also
Price,disambiguation
This,disambiguation,page,lists,articles,associated,with,the,title,Prize
If,an,internal,link,led,you,here,,you,may,wish,to,change,the,link,to,point,directly,to,the,intended,article
prize,bond,,prize,bond,schedule,2018,,prize,bond,results,,prize,bond,draw,2018,Prize,(disambiguation)
,
- published: 26 Jun 2019
- views: 3
-
IP3 DAG Calcium Pathway
IP3-mediated signal transduction pathways
First messengers are extracellular signaling molecules, such as hormones or neurotransmitters. In response to exposure to these first messengers, intracellular signaling molecules called second messengers are released by the cell. Two such second messengers are IP3 and DAG.
Calcium is also an important second messenger. Transient increases in cytoplasmic Ca2+ levels are caused by the binding of some hormones and signal molecules, and this can send important intracellular signals, by activating calcium-binding proteins that then perform various functions. Note that cytosolic increases in calcium concentration can occur in two ways. There are reservoirs of calcium that can be opened within the cell by the second messenger IP3 – the endoplasmic retic...
published: 13 Oct 2019
-
Phosphatidylinositol pathway
This cell signaling lecture explains about Phosphatidylinositol signal pathway. http://shomusbiology.com/
Download the study materials here-
http://shomusbiology.com/bio-materials.html
Remember Shomu’s Biology is created to spread the knowledge of life science and biology by sharing all this free biology lectures video and animation presented by Suman Bhattacharjee in YouTube. All these tutorials are brought to you for free. Please subscribe to our channel so that we can grow together. You can check for any of the following services from Shomu’s Biology-
Buy Shomu’s Biology lecture DVD set- www.shomusbiology.com/dvd-store
Shomu’s Biology assignment services – www.shomusbiology.com/assignment -help
Join Online coaching for CSIR NET exam – www.shomusbiology.com/net-coaching
We are social. F...
published: 07 Dec 2012
-
AKT/PKB Signaling Pathway | PI3k Signaling
This video will be encompass the AKT/PKB Signaling Pathway .
The Akt Pathway, or PI3K-Akt Pathway is a signal transduction pathway that promotes survival and growth in response to extracellular signals. Key proteins involved are PI3K (phosphatidylinositol 3-kinase) and Akt (Protein Kinase B).
Initial stimulation by one of the growth factors causes activation of a cell surface receptor and phosphorylation of PI3K. Activated PI3K then phosphorylates lipids on the plasma membrane, forming second messenger phosphatidylinositol (3,4,5)-trisphosphate (PIP3). Akt, a serine/threonine kinase, is recruited to the membrane by interaction with these phosphoinositide docking sites, so that it can be fully activated.[1] Activated Akt mediates downstream responses, including cell survival, growth, prolif...
published: 10 Jun 2020
-
PI3K / Akt Upstream Signaling from Cell Signaling Technology, Inc.
The PI3K/Akt signaling pathway controls a variety of cellular functions including glucose metabolism, cell survival, proliferation, and invasiveness. Due to its role in these important processes, proper regulation is critical as constitutive activation of Akt has been observed in a variety of cancers including neuroblastoma, breast cancer, and prostate cancer. In this video, we use pan and phospho specific Akt antibodies from Cell Signaling Technology (CST) for an in-depth review the upstream signaling events that regulate Akt using confocal immunofluorescent analysis.
The PI3K/Akt pathway is initiated when growth factors or cytokines signal through membrane receptors including receptor tyrosine kinases (RTKs), cytokine receptors, G-protein coupled receptors, B-cell receptors, and integrin...
published: 19 Aug 2010
-
Medical vocabulary: What does Phosphatidylinositol 4,5-Diphosphate mean
What does Phosphatidylinositol 4,5-Diphosphate mean in English?
published: 19 Jan 2016
-
Phosphatidylinositol-4,5-Bisphosphate 4-Phosphatase
Phosphatidylinositol-4,5-bisphosphate 4-phosphatase (EC 3.1.3.78, phosphatidylinositol-4,5-bisphosphate 4-phosphatase I, phosphatidylinositol-4,5-bisphosphate 4-phosphatase II, type I PtdIns-4,5-P2 4-Ptase, type II PtdIns-4,5-P2 4-Ptase, IpgD, PtdIns-4,5-P2 4-phosphatase type I, PtdIns-4,5-P2 4-phosphatase type II, type I phosphatidylinositol-4,5-bisphosphate 4-phosphatase, type 1 4-phosphatase) is an enzyme with systematic name 1-phosphatidyl-1D-myo-inositol-4,5-bisphosphate 4-phosphohydrolase. This enzyme catalyses the following chemical reaction
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O
⇌
{\displaystyle \rightleftharpoons }
1-phosphatidyl-1D-myo-inositol 5-phosphate + phosphateThis enzyme participates in one of the mammalian pathwa...
published: 29 Oct 2020
-
Protein kinase C HD
The second messenger PIP3 formed by PI3K can be hydrolyzed to PIP2 by the phosphatase PTEN. PIP2 can be hydrolyzed to diacyl glycerol (DAG) and inositol trisphosphate (IP3) by phospholipase C (PLC). IP3 dissociates from the membrane into the cell, where it opens channels of intracellular vesicles, which store calcium. As a result, the intracellular intracellular calcium level rises. Calcium binds to protein kinase C (PKC) which is now able to bind to DAG, leading to the activation of the enzyme. Active PKC has many effects, e.g. phosphorylation and activation of the proto-oncoprotein Raf kinase.
#onkoview, #kinase, #pip3, #pip2, #cell
published: 07 Feb 2022
-
phosphoinositol signaling cascade
published: 22 Nov 2018
-
Protein kinase C
The second messenger PIP3 formed by PI3K can be hydrolyzed to PIP2 by the phosphatase PTEN. PIP2 can be hydrolyzed to diacyl glycerol (DAG) and inositol trisphosphate (IP3) by phospholipase C (PLC). IP3 dissociates from the membrane into the cell, where it opens channels of intracellular vesicles, which store calcium. As a result, the intracellular intracellular calcium level rises. Calcium binds to protein kinase C (PKC) which is now able to bind to DAG, leading to the activation of the enzyme. Active PKC has many effects, e.g. phosphorylation and activation of the proto-oncoprotein Raf kinase.
published: 22 Feb 2010
-
Phosphatidyl-inositol Phosphorylation | PLC | PI3P
This video from B for Biology includes Phospatidyl inositol phosphorylation, its derivatives and PLC.
If you like the video,
Please do Like, Subscribe and Share.
Thank you
published: 20 Mar 2018
3:27
IP3 DAG Calcium Pathway
IP3-mediated signal transduction pathways
First messengers are extracellular signaling molecules, such as hormones or neurotransmitters. In response to exposure...
IP3-mediated signal transduction pathways
First messengers are extracellular signaling molecules, such as hormones or neurotransmitters. In response to exposure to these first messengers, intracellular signaling molecules called second messengers are released by the cell. Two such second messengers are IP3 and DAG.
Calcium is also an important second messenger. Transient increases in cytoplasmic Ca2+ levels are caused by the binding of some hormones and signal molecules, and this can send important intracellular signals, by activating calcium-binding proteins that then perform various functions. Note that cytosolic increases in calcium concentration can occur in two ways. There are reservoirs of calcium that can be opened within the cell by the second messenger IP3 – the endoplasmic reticulum and calciosomes. Otherwise, cyclic AMP can activate the opening of calcium channels in the plasma membrane so that extracellular calcium can rush in.
G-protein-coupled receptors, or GPCRs, are integral membrane proteins, meaning that they are locked into the cell membrane. They are locked in via 7 transmembrane α-helical segments. GPCRs recognize ligands through an extracellular recognition site. They also have an intracellular recognition site for a G protein. When a ligand binds the extracellular recognition site of a GPCR, this induces a conformational change, activating the G-Protein.
There are different kinds of G proteins, sometimes also called membrane-associated heterotrimeric G proteins. Gs activates adenylyl cyclase. Gi inhibits adenylyl cyclase.
Gq has three subunits – α, β, and γ. A conformational change in the GPCR activates the G protein. When this happens, the GDP on the Gα subunit gets replaced by GTP. This drives dissociation of the Gα subunit from the Gβγ complex. The now free Gα subunit can activate Phospholipase C-β.
Phosphatidylinositol-4-P (PIP) and phosphatidylinositol-4,5-biphosphate (PIP2) are produced through successive phorphorylations of phosphatidylinositol (PI). Once it is activated by a G-protein, Phospholipase C-β can break down PIP2.
PIP2 is hydrolyzed by phospholipase-C to produce inositol-1,4,5-triphosphate (IP3) and diacylglycerol (DAG), both of which act as second messengers. IP3 is hydrophilic, and diffuses into the cell, while DAG is lipophilic, and hence remains in the cell membrane. IP3 binds to calcium channel on endoplasmic reticulum (or the sarcoplasmic reticulum in the case of muscle cells) and allows release of calcium from the endoplasmic reticulum lumen. DAG, with the help of the calcium released from the endoplasmic reticulum, activates the calcium-dependent Protein Kinase C. Once activated, protein kinase C adds phosphates to target proteins and causes cellular responses.
https://wn.com/Ip3_Dag_Calcium_Pathway
IP3-mediated signal transduction pathways
First messengers are extracellular signaling molecules, such as hormones or neurotransmitters. In response to exposure to these first messengers, intracellular signaling molecules called second messengers are released by the cell. Two such second messengers are IP3 and DAG.
Calcium is also an important second messenger. Transient increases in cytoplasmic Ca2+ levels are caused by the binding of some hormones and signal molecules, and this can send important intracellular signals, by activating calcium-binding proteins that then perform various functions. Note that cytosolic increases in calcium concentration can occur in two ways. There are reservoirs of calcium that can be opened within the cell by the second messenger IP3 – the endoplasmic reticulum and calciosomes. Otherwise, cyclic AMP can activate the opening of calcium channels in the plasma membrane so that extracellular calcium can rush in.
G-protein-coupled receptors, or GPCRs, are integral membrane proteins, meaning that they are locked into the cell membrane. They are locked in via 7 transmembrane α-helical segments. GPCRs recognize ligands through an extracellular recognition site. They also have an intracellular recognition site for a G protein. When a ligand binds the extracellular recognition site of a GPCR, this induces a conformational change, activating the G-Protein.
There are different kinds of G proteins, sometimes also called membrane-associated heterotrimeric G proteins. Gs activates adenylyl cyclase. Gi inhibits adenylyl cyclase.
Gq has three subunits – α, β, and γ. A conformational change in the GPCR activates the G protein. When this happens, the GDP on the Gα subunit gets replaced by GTP. This drives dissociation of the Gα subunit from the Gβγ complex. The now free Gα subunit can activate Phospholipase C-β.
Phosphatidylinositol-4-P (PIP) and phosphatidylinositol-4,5-biphosphate (PIP2) are produced through successive phorphorylations of phosphatidylinositol (PI). Once it is activated by a G-protein, Phospholipase C-β can break down PIP2.
PIP2 is hydrolyzed by phospholipase-C to produce inositol-1,4,5-triphosphate (IP3) and diacylglycerol (DAG), both of which act as second messengers. IP3 is hydrophilic, and diffuses into the cell, while DAG is lipophilic, and hence remains in the cell membrane. IP3 binds to calcium channel on endoplasmic reticulum (or the sarcoplasmic reticulum in the case of muscle cells) and allows release of calcium from the endoplasmic reticulum lumen. DAG, with the help of the calcium released from the endoplasmic reticulum, activates the calcium-dependent Protein Kinase C. Once activated, protein kinase C adds phosphates to target proteins and causes cellular responses.
- published: 13 Oct 2019
- views: 182029
5:42
Phosphatidylinositol pathway
This cell signaling lecture explains about Phosphatidylinositol signal pathway. http://shomusbiology.com/
Download the study materials here-
http://shomusbiolog...
This cell signaling lecture explains about Phosphatidylinositol signal pathway. http://shomusbiology.com/
Download the study materials here-
http://shomusbiology.com/bio-materials.html
Remember Shomu’s Biology is created to spread the knowledge of life science and biology by sharing all this free biology lectures video and animation presented by Suman Bhattacharjee in YouTube. All these tutorials are brought to you for free. Please subscribe to our channel so that we can grow together. You can check for any of the following services from Shomu’s Biology-
Buy Shomu’s Biology lecture DVD set- www.shomusbiology.com/dvd-store
Shomu’s Biology assignment services – www.shomusbiology.com/assignment -help
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Thank you for watching
Phosphatidylinositide 3-kinases (PI 3-kinases or PI3Ks) are a family of enzymes involved in cellular functions such as cell growth, proliferation, differentiation, motility, survival and intracellular trafficking, which in turn are involved in cancer. PI3Ks are a family of related intracellular signal transducer enzymes capable of phosphorylating the 3 position hydroxyl group of the inositol ring of phosphatidylinositol (PtdIns).[2] They are also known as phosphatidylinositol-3-kinases. The pathway, with oncogene PIK3CA and tumor suppressor PTEN (gene), is implicated in insensitivity of cancer tumors to insulin and IGF1, in calorie restriction.[3][4] Source of the article published in description is Wikipedia. I am sharing their material. © by original content developers of Wikipedia.
Link- http://en.wikipedia.org/wiki/Main_Page
https://wn.com/Phosphatidylinositol_Pathway
This cell signaling lecture explains about Phosphatidylinositol signal pathway. http://shomusbiology.com/
Download the study materials here-
http://shomusbiology.com/bio-materials.html
Remember Shomu’s Biology is created to spread the knowledge of life science and biology by sharing all this free biology lectures video and animation presented by Suman Bhattacharjee in YouTube. All these tutorials are brought to you for free. Please subscribe to our channel so that we can grow together. You can check for any of the following services from Shomu’s Biology-
Buy Shomu’s Biology lecture DVD set- www.shomusbiology.com/dvd-store
Shomu’s Biology assignment services – www.shomusbiology.com/assignment -help
Join Online coaching for CSIR NET exam – www.shomusbiology.com/net-coaching
We are social. Find us on different sites here-
Our Website – www.shomusbiology.com
Facebook page- https://www.facebook.com/ShomusBiology/
Twitter - https://twitter.com/shomusbiology
SlideShare- www.slideshare.net/shomusbiology
Google plus- https://plus.google.com/113648584982732129198
LinkedIn - https://www.linkedin.com/in/suman-bhattacharjee-2a051661
Youtube- https://www.youtube.com/user/TheFunsuman
Thank you for watching
Phosphatidylinositide 3-kinases (PI 3-kinases or PI3Ks) are a family of enzymes involved in cellular functions such as cell growth, proliferation, differentiation, motility, survival and intracellular trafficking, which in turn are involved in cancer. PI3Ks are a family of related intracellular signal transducer enzymes capable of phosphorylating the 3 position hydroxyl group of the inositol ring of phosphatidylinositol (PtdIns).[2] They are also known as phosphatidylinositol-3-kinases. The pathway, with oncogene PIK3CA and tumor suppressor PTEN (gene), is implicated in insensitivity of cancer tumors to insulin and IGF1, in calorie restriction.[3][4] Source of the article published in description is Wikipedia. I am sharing their material. © by original content developers of Wikipedia.
Link- http://en.wikipedia.org/wiki/Main_Page
- published: 07 Dec 2012
- views: 48258
4:16
AKT/PKB Signaling Pathway | PI3k Signaling
This video will be encompass the AKT/PKB Signaling Pathway .
The Akt Pathway, or PI3K-Akt Pathway is a signal transduction pathway that promotes survival and gr...
This video will be encompass the AKT/PKB Signaling Pathway .
The Akt Pathway, or PI3K-Akt Pathway is a signal transduction pathway that promotes survival and growth in response to extracellular signals. Key proteins involved are PI3K (phosphatidylinositol 3-kinase) and Akt (Protein Kinase B).
Initial stimulation by one of the growth factors causes activation of a cell surface receptor and phosphorylation of PI3K. Activated PI3K then phosphorylates lipids on the plasma membrane, forming second messenger phosphatidylinositol (3,4,5)-trisphosphate (PIP3). Akt, a serine/threonine kinase, is recruited to the membrane by interaction with these phosphoinositide docking sites, so that it can be fully activated.[1] Activated Akt mediates downstream responses, including cell survival, growth, proliferation, cell migration and angiogenesis, by phosphorylating a range of intracellular proteins. The pathway is present in all cells of higher eukaryotes and is highly conserved.
There are multiple types of phosphoinositide 3-kinase but only class I are responsible for lipid phosphorylation in response to growth stimuli.
Akt resides in the cytosol in an inactive conformation, until the cell is stimulated and it translocates to the plasma membrane. The Akt PH domain has a high affinity for second messenger PI(3,4,5)P3, binding to it preferentially over other phosphoinositides.[11] Thus PI3K activity is essential for translocation of Akt to the membrane. Interaction with PI(3,4,5)P3 causes conformational changes and exposure of phosphorylation sites Thr308 in the kinase domain and Ser473 in the C-terminal domain. Akt is partially activated by phosphorylation of T308 by PDK1. Full activation requires phosphorylation of S473, which can be catalysed by multiple proteins, including phosphoinositide-dependent kinase 2 (PDK2), integrin-linked kinase (ILK)
https://wn.com/Akt_Pkb_Signaling_Pathway_|_Pi3K_Signaling
This video will be encompass the AKT/PKB Signaling Pathway .
The Akt Pathway, or PI3K-Akt Pathway is a signal transduction pathway that promotes survival and growth in response to extracellular signals. Key proteins involved are PI3K (phosphatidylinositol 3-kinase) and Akt (Protein Kinase B).
Initial stimulation by one of the growth factors causes activation of a cell surface receptor and phosphorylation of PI3K. Activated PI3K then phosphorylates lipids on the plasma membrane, forming second messenger phosphatidylinositol (3,4,5)-trisphosphate (PIP3). Akt, a serine/threonine kinase, is recruited to the membrane by interaction with these phosphoinositide docking sites, so that it can be fully activated.[1] Activated Akt mediates downstream responses, including cell survival, growth, proliferation, cell migration and angiogenesis, by phosphorylating a range of intracellular proteins. The pathway is present in all cells of higher eukaryotes and is highly conserved.
There are multiple types of phosphoinositide 3-kinase but only class I are responsible for lipid phosphorylation in response to growth stimuli.
Akt resides in the cytosol in an inactive conformation, until the cell is stimulated and it translocates to the plasma membrane. The Akt PH domain has a high affinity for second messenger PI(3,4,5)P3, binding to it preferentially over other phosphoinositides.[11] Thus PI3K activity is essential for translocation of Akt to the membrane. Interaction with PI(3,4,5)P3 causes conformational changes and exposure of phosphorylation sites Thr308 in the kinase domain and Ser473 in the C-terminal domain. Akt is partially activated by phosphorylation of T308 by PDK1. Full activation requires phosphorylation of S473, which can be catalysed by multiple proteins, including phosphoinositide-dependent kinase 2 (PDK2), integrin-linked kinase (ILK)
- published: 10 Jun 2020
- views: 50790
5:31
PI3K / Akt Upstream Signaling from Cell Signaling Technology, Inc.
The PI3K/Akt signaling pathway controls a variety of cellular functions including glucose metabolism, cell survival, proliferation, and invasiveness. Due to its...
The PI3K/Akt signaling pathway controls a variety of cellular functions including glucose metabolism, cell survival, proliferation, and invasiveness. Due to its role in these important processes, proper regulation is critical as constitutive activation of Akt has been observed in a variety of cancers including neuroblastoma, breast cancer, and prostate cancer. In this video, we use pan and phospho specific Akt antibodies from Cell Signaling Technology (CST) for an in-depth review the upstream signaling events that regulate Akt using confocal immunofluorescent analysis.
The PI3K/Akt pathway is initiated when growth factors or cytokines signal through membrane receptors including receptor tyrosine kinases (RTKs), cytokine receptors, G-protein coupled receptors, B-cell receptors, and integrin receptors. These receptors signal through PI3K which in turn phosphorylates PIP2, converting it into PIP3. PIP3 then binds to the PH domain of Akt, anchoring it to the cell membrane where the kinase PDK1 and mTORC2 complex activates the membrane bound Akt through phosphorylation on Thr308 and Ser473 respectively. This triggers activation of downstream proteins (substrates). PI3K/Akt signaling is inactivated when the phosphatase PTEN converts PIP3 back to PIP2, leaving Akt in its inactive dephosphorylated state.
Visit http://www.cellsignal.com to see antibodies for the study of Akt Signaling.
https://wn.com/Pi3K_Akt_Upstream_Signaling_From_Cell_Signaling_Technology,_Inc.
The PI3K/Akt signaling pathway controls a variety of cellular functions including glucose metabolism, cell survival, proliferation, and invasiveness. Due to its role in these important processes, proper regulation is critical as constitutive activation of Akt has been observed in a variety of cancers including neuroblastoma, breast cancer, and prostate cancer. In this video, we use pan and phospho specific Akt antibodies from Cell Signaling Technology (CST) for an in-depth review the upstream signaling events that regulate Akt using confocal immunofluorescent analysis.
The PI3K/Akt pathway is initiated when growth factors or cytokines signal through membrane receptors including receptor tyrosine kinases (RTKs), cytokine receptors, G-protein coupled receptors, B-cell receptors, and integrin receptors. These receptors signal through PI3K which in turn phosphorylates PIP2, converting it into PIP3. PIP3 then binds to the PH domain of Akt, anchoring it to the cell membrane where the kinase PDK1 and mTORC2 complex activates the membrane bound Akt through phosphorylation on Thr308 and Ser473 respectively. This triggers activation of downstream proteins (substrates). PI3K/Akt signaling is inactivated when the phosphatase PTEN converts PIP3 back to PIP2, leaving Akt in its inactive dephosphorylated state.
Visit http://www.cellsignal.com to see antibodies for the study of Akt Signaling.
- published: 19 Aug 2010
- views: 21722
1:16
Phosphatidylinositol-4,5-Bisphosphate 4-Phosphatase
Phosphatidylinositol-4,5-bisphosphate 4-phosphatase (EC 3.1.3.78, phosphatidylinositol-4,5-bisphosphate 4-phosphatase I, phosphatidylinositol-4,5-bisphosphate 4...
Phosphatidylinositol-4,5-bisphosphate 4-phosphatase (EC 3.1.3.78, phosphatidylinositol-4,5-bisphosphate 4-phosphatase I, phosphatidylinositol-4,5-bisphosphate 4-phosphatase II, type I PtdIns-4,5-P2 4-Ptase, type II PtdIns-4,5-P2 4-Ptase, IpgD, PtdIns-4,5-P2 4-phosphatase type I, PtdIns-4,5-P2 4-phosphatase type II, type I phosphatidylinositol-4,5-bisphosphate 4-phosphatase, type 1 4-phosphatase) is an enzyme with systematic name 1-phosphatidyl-1D-myo-inositol-4,5-bisphosphate 4-phosphohydrolase. This enzyme catalyses the following chemical reaction
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O
⇌
{\displaystyle \rightleftharpoons }
1-phosphatidyl-1D-myo-inositol 5-phosphate + phosphateThis enzyme participates in one of the mammalian pathways for degradation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate [PtdIns(4,5)P2].
https://wn.com/Phosphatidylinositol_4,5_Bisphosphate_4_Phosphatase
Phosphatidylinositol-4,5-bisphosphate 4-phosphatase (EC 3.1.3.78, phosphatidylinositol-4,5-bisphosphate 4-phosphatase I, phosphatidylinositol-4,5-bisphosphate 4-phosphatase II, type I PtdIns-4,5-P2 4-Ptase, type II PtdIns-4,5-P2 4-Ptase, IpgD, PtdIns-4,5-P2 4-phosphatase type I, PtdIns-4,5-P2 4-phosphatase type II, type I phosphatidylinositol-4,5-bisphosphate 4-phosphatase, type 1 4-phosphatase) is an enzyme with systematic name 1-phosphatidyl-1D-myo-inositol-4,5-bisphosphate 4-phosphohydrolase. This enzyme catalyses the following chemical reaction
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O
⇌
{\displaystyle \rightleftharpoons }
1-phosphatidyl-1D-myo-inositol 5-phosphate + phosphateThis enzyme participates in one of the mammalian pathways for degradation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate [PtdIns(4,5)P2].
- published: 29 Oct 2020
- views: 54
3:59
Protein kinase C HD
The second messenger PIP3 formed by PI3K can be hydrolyzed to PIP2 by the phosphatase PTEN. PIP2 can be hydrolyzed to diacyl glycerol (DAG) and inositol trispho...
The second messenger PIP3 formed by PI3K can be hydrolyzed to PIP2 by the phosphatase PTEN. PIP2 can be hydrolyzed to diacyl glycerol (DAG) and inositol trisphosphate (IP3) by phospholipase C (PLC). IP3 dissociates from the membrane into the cell, where it opens channels of intracellular vesicles, which store calcium. As a result, the intracellular intracellular calcium level rises. Calcium binds to protein kinase C (PKC) which is now able to bind to DAG, leading to the activation of the enzyme. Active PKC has many effects, e.g. phosphorylation and activation of the proto-oncoprotein Raf kinase.
#onkoview, #kinase, #pip3, #pip2, #cell
https://wn.com/Protein_Kinase_C_Hd
The second messenger PIP3 formed by PI3K can be hydrolyzed to PIP2 by the phosphatase PTEN. PIP2 can be hydrolyzed to diacyl glycerol (DAG) and inositol trisphosphate (IP3) by phospholipase C (PLC). IP3 dissociates from the membrane into the cell, where it opens channels of intracellular vesicles, which store calcium. As a result, the intracellular intracellular calcium level rises. Calcium binds to protein kinase C (PKC) which is now able to bind to DAG, leading to the activation of the enzyme. Active PKC has many effects, e.g. phosphorylation and activation of the proto-oncoprotein Raf kinase.
#onkoview, #kinase, #pip3, #pip2, #cell
- published: 07 Feb 2022
- views: 2777
3:56
Protein kinase C
The second messenger PIP3 formed by PI3K can be hydrolyzed to PIP2 by the phosphatase PTEN. PIP2 can be hydrolyzed to diacyl glycerol (DAG) and inositol trispho...
The second messenger PIP3 formed by PI3K can be hydrolyzed to PIP2 by the phosphatase PTEN. PIP2 can be hydrolyzed to diacyl glycerol (DAG) and inositol trisphosphate (IP3) by phospholipase C (PLC). IP3 dissociates from the membrane into the cell, where it opens channels of intracellular vesicles, which store calcium. As a result, the intracellular intracellular calcium level rises. Calcium binds to protein kinase C (PKC) which is now able to bind to DAG, leading to the activation of the enzyme. Active PKC has many effects, e.g. phosphorylation and activation of the proto-oncoprotein Raf kinase.
https://wn.com/Protein_Kinase_C
The second messenger PIP3 formed by PI3K can be hydrolyzed to PIP2 by the phosphatase PTEN. PIP2 can be hydrolyzed to diacyl glycerol (DAG) and inositol trisphosphate (IP3) by phospholipase C (PLC). IP3 dissociates from the membrane into the cell, where it opens channels of intracellular vesicles, which store calcium. As a result, the intracellular intracellular calcium level rises. Calcium binds to protein kinase C (PKC) which is now able to bind to DAG, leading to the activation of the enzyme. Active PKC has many effects, e.g. phosphorylation and activation of the proto-oncoprotein Raf kinase.
- published: 22 Feb 2010
- views: 73853
10:05
Phosphatidyl-inositol Phosphorylation | PLC | PI3P
This video from B for Biology includes Phospatidyl inositol phosphorylation, its derivatives and PLC.
If you like the video,
Please do Like, Subscribe and Shar...
This video from B for Biology includes Phospatidyl inositol phosphorylation, its derivatives and PLC.
If you like the video,
Please do Like, Subscribe and Share.
Thank you
https://wn.com/Phosphatidyl_Inositol_Phosphorylation_|_Plc_|_Pi3P
This video from B for Biology includes Phospatidyl inositol phosphorylation, its derivatives and PLC.
If you like the video,
Please do Like, Subscribe and Share.
Thank you
- published: 20 Mar 2018
- views: 547