Spindle cell carcinoma is a type of cancer that begins in the skin or in tissues that line or cover internal organs and that contains long spindle-shaped cells. Also called sarcomatoid carcinoma.
In cell biology, the spindle apparatus refers to the cytoskeletal structure of eukaryotic cells that forms during cell division to separate sister chromatids between daughter cells. It is referred to as the mitotic spindle during mitosis, a process that produces genetically identical daughter cells, or the meiotic spindle during meiosis, a process that produces gametes with half the number of chromosomes of the parent cell.
Besides chromosomes, the spindle apparatus is composed of hundreds of proteins.Microtubules comprise the most abundant components of the machinery.
Spindle structure
Attachment of microtubules to chromosomes is mediated by kinetochores, which actively monitor spindle formation and prevent premature anaphase onset. Microtubule polymerization and depolymerization dynamics drive chromosome congression. Depolymerization of microtubules generates tension at kinetochores; bipolar attachment of sister kinetochores to microtubules emanating from opposite cell poles couples opposing tension forces, aligning chromosomes at the cell equator and poising them for segregation to daughter cells. Once every chromosome is bi-oriented, anaphase commences and cohesin, which couples sister chromatids, is severed, permitting the transit of the sister chromatids to opposite poles.
Spindle neurons, also called von Economo neurons (VENs), are a specific class of neurons that are characterized by a large spindle-shaped soma (or body), gradually tapering into a single apicalaxon in one direction, with only a single dendrite facing opposite. Other neurons tend to have many dendrites, and the polar-shaped morphology of spindle neurons is unique. A neuron's dendrites receive signals, and its axon sends them.
Pathology Insights: Challenging Cutaneous Spindle Cell Tumors with Steven Billings, MD
For more information on Cleveland Clinic’s Pathology & Laboratory Medicine Institute, please visit https://cle.clinic/3vmekpI
Pathologist Steven Billings, MD, covers a set of challenging cutaneous spindle cell tumors, emphasizing a practical approach and key histologic features that allow accurate diagnosis.
▶Share this video with others: https://youtu.be/9_cnMlD4PdM
▶Subscribe to learn more about Cleveland Clinic: https://www.youtube.com/user/ClevelandClinic?sub_confirmation=1
A single case review of histology, clinical features, and genetic abnormalities seen in metaplastic carcinoma of the breast - spindle cell carcinoma. Includes routine H&E, CK903 (34BE12), and p63 stains.
This video is for educational purposes only and does not represent or replace medical advice. Please consult your physician if you have questions as a patient. If you are a physician, please ensure you research subjects to ensure you have the most up to date information.
All content presented by KL Roncin, MD, unless otherwise noted. Comments and opinions are my own and are current as of the time the video was taken, unless otherwise noted. Please like and subscribe to my channel to receive notifications on any new pathology content!
Follow Me:
Twitter: @KRoSlideReview
@Ro...
published: 16 Mar 2020
APPROACH TO MALIGNANT SPINDLE CELL NEOPLASMS|ROLE OF IHC IN MALIGNANT SPINDLE CELL TUMORS
FOLLOW ME ON SOCIAL MEDIA AND MY BLOG
https://t.me/EKDINKARAJAPATHOLOGYNOTES
www.linkedin.com/in/afreen-khan-3528a3b3
https://www.facebook.com/yasmeen.khan.12177276
https://twitter.com/khanspathology
https://www.instagram.com/khanspathology/
https://rb.gy/8gv5mm
https://khan-pathology-2021.blogspot.com/2021/01/morphological-changes-in-palcenta-in.html
https://rb.gy/hxyfwr
https://www.linkedin.com/pulse/kimura-disease-afreen-khan
https://www.linkedin.com/posts/afreen-khan-3528a3b3_kikuchi-necrotizing-sle-activity-6758077476074876928-8fw1
https://rb.gy/keovsg
https://khan-hematopathology-2021.blogspot.com/2021/01/hereditary-spherocytosis.html
https://khan-pathology-2021.blogspot.com/
https://khan-hematopathology-2021.blogspot.com/
https://rb.gy/l44a4v
https://rb.gy/ypx8iq
https://rb.gy/ea...
published: 19 Feb 2021
Breast spindle cell lesions - Dr. Cimino-Mathews (Hopkins) #BREASTPATH
Here's my sample pathology report template for AFX vs pleomorphic dermal sarcoma: https://kikoxp.com/posts/5193. A complete organized library of all my videos, digital slides, pics, & sample pathology reports is available here: https://kikoxp.com/posts/5084 (dermpath) & https://kikoxp.com/posts/5083 (bone/soft tissue sarcoma pathology).
This video from 2016 discusses the basic workup of a pleomorphic malignant cutaneous spindle cell tumor. The main differential diagnosis includes spindle cell melanoma, spindle cell squamous cell carcinoma, and atypical fibroxanthoma (AFX). Other entities in the differential include leiomyosarcoma, spindle cell angiosarcoma, and (very rarely) cutaneous rhabdomyosarcoma. A panel of S100 protein (or SOX-10), p63/p40 (and/or cytokeratins), desmin, and ERG (o...
published: 17 Aug 2016
Dr. Michael Alan Hernandez tackles the causes and treatment for spindle cell sarcoma. | Salamat Dok
Dr. Michael Alan Hernandez tackles the causes and treatment for spindle cell sarcoma. Fuda Cancer Hospital Dr. Mu Feng talks about the telltale signs and symptoms, and treatment for soft tissue sarcoma.
For more Salamat Dok videos, click the link below:
https://www.youtube.com/watch?v=AmPbO5C5Fkw&list=PLgyY1WylJUmh4e4yWhmg57VlzI9hf0xmB
To watch Mission Possible videos, click the link below:
https://www.youtube.com/playlist?list=PLgyY1WylJUmgD28BO6j_rU5FOUW2WeyFS
To watch Matanglawin videos, click link below:
https://www.youtube.com/playlist?list=PLgyY1WylJUmjr1WJSMOegDYXmHBa20_oZ
Subscribe to the ABS-CBN News channel! - http://bit.ly/TheABSCBNNews
Watch the full episodes of Salamat Dok on TFC.TV
http://bit.ly/SalamatDok-TFCTV
and on iWant for Philippine viewers, click:
http://bit...
For more information on Cleveland Clinic’s Pathology & Laboratory Medicine Institute, please visit https://cle.clinic/3vmekpI
Pathologist Steven Billings, MD, ...
For more information on Cleveland Clinic’s Pathology & Laboratory Medicine Institute, please visit https://cle.clinic/3vmekpI
Pathologist Steven Billings, MD, covers a set of challenging cutaneous spindle cell tumors, emphasizing a practical approach and key histologic features that allow accurate diagnosis.
▶Share this video with others: https://youtu.be/9_cnMlD4PdM
▶Subscribe to learn more about Cleveland Clinic: https://www.youtube.com/user/ClevelandClinic?sub_confirmation=1
For more information on Cleveland Clinic’s Pathology & Laboratory Medicine Institute, please visit https://cle.clinic/3vmekpI
Pathologist Steven Billings, MD, covers a set of challenging cutaneous spindle cell tumors, emphasizing a practical approach and key histologic features that allow accurate diagnosis.
▶Share this video with others: https://youtu.be/9_cnMlD4PdM
▶Subscribe to learn more about Cleveland Clinic: https://www.youtube.com/user/ClevelandClinic?sub_confirmation=1
A single case review of histology, clinical features, and genetic abnormalities seen in metaplastic carcinoma of the breast - spindle cell carcinoma. Includes r...
A single case review of histology, clinical features, and genetic abnormalities seen in metaplastic carcinoma of the breast - spindle cell carcinoma. Includes routine H&E, CK903 (34BE12), and p63 stains.
This video is for educational purposes only and does not represent or replace medical advice. Please consult your physician if you have questions as a patient. If you are a physician, please ensure you research subjects to ensure you have the most up to date information.
All content presented by KL Roncin, MD, unless otherwise noted. Comments and opinions are my own and are current as of the time the video was taken, unless otherwise noted. Please like and subscribe to my channel to receive notifications on any new pathology content!
Follow Me:
Twitter: @KRoSlideReview
@RoncinMD
A single case review of histology, clinical features, and genetic abnormalities seen in metaplastic carcinoma of the breast - spindle cell carcinoma. Includes routine H&E, CK903 (34BE12), and p63 stains.
This video is for educational purposes only and does not represent or replace medical advice. Please consult your physician if you have questions as a patient. If you are a physician, please ensure you research subjects to ensure you have the most up to date information.
All content presented by KL Roncin, MD, unless otherwise noted. Comments and opinions are my own and are current as of the time the video was taken, unless otherwise noted. Please like and subscribe to my channel to receive notifications on any new pathology content!
Follow Me:
Twitter: @KRoSlideReview
@RoncinMD
FOLLOW ME ON SOCIAL MEDIA AND MY BLOG
https://t.me/EKDINKARAJAPATHOLOGYNOTES
www.linkedin.com/in/afreen-khan-3528a3b3
https://www.facebook.com/yasmeen.khan.1217...
FOLLOW ME ON SOCIAL MEDIA AND MY BLOG
https://t.me/EKDINKARAJAPATHOLOGYNOTES
www.linkedin.com/in/afreen-khan-3528a3b3
https://www.facebook.com/yasmeen.khan.12177276
https://twitter.com/khanspathology
https://www.instagram.com/khanspathology/
https://rb.gy/8gv5mm
https://khan-pathology-2021.blogspot.com/2021/01/morphological-changes-in-palcenta-in.html
https://rb.gy/hxyfwr
https://www.linkedin.com/pulse/kimura-disease-afreen-khan
https://www.linkedin.com/posts/afreen-khan-3528a3b3_kikuchi-necrotizing-sle-activity-6758077476074876928-8fw1
https://rb.gy/keovsg
https://khan-hematopathology-2021.blogspot.com/2021/01/hereditary-spherocytosis.html
https://khan-pathology-2021.blogspot.com/
https://khan-hematopathology-2021.blogspot.com/
https://rb.gy/l44a4v
https://rb.gy/ypx8iq
https://rb.gy/eaipyq
https://9c298etz1jfovarwzavjn02i3l.hop.clickbank.net/
https://rb.gy/xpy7mz
https://rb.gy/egazss
https://cdd2bdl2yjesn8sy3dsiteqa40.hop.clickbank.net/
https://rb.gy/tcb2mp
https://rb.gy/tcb2mp
https://rb.gy/ftztml
https://rb.gy/uhqzwv
https://rb.gy/jg0eth
https://rb.gy/ezfmlp
https://rb.gy/bpzucl
https://rb.gy/bsueld
https://9c298etz1jfovarwzavjn02i3l.hop.clickbank.net/
https://rb.gy/os5asi
I'm not here to teach lessons of pathology which is been done by many people on YouTube and many webinars have been conducted in this pandemic so this is a unique platform of it's kind to help exam going pathology students(MBBS/RESIDENTS/FELLOWS) to excel their university exams..to provide those 10 headings/key points which every student wants to revise on the day of exam, even every examiner expects those points to be represented in the paper to give maximum marks..will try to provide maximum information in the form of flow charts,diagrams,tables and images which are easy to review and represent in the exam..last but not the least the senior consultants/faculty /examiners/guides can refresh/update their knowledge with the advancing world of pathology by simply spending couple of minutes on the video.
FOLLOW ME ON SOCIAL MEDIA AND MY BLOG
https://t.me/EKDINKARAJAPATHOLOGYNOTES
www.linkedin.com/in/afreen-khan-3528a3b3
https://www.facebook.com/yasmeen.khan.12177276
https://twitter.com/khanspathology
https://www.instagram.com/khanspathology/
https://rb.gy/8gv5mm
https://khan-pathology-2021.blogspot.com/2021/01/morphological-changes-in-palcenta-in.html
https://rb.gy/hxyfwr
https://www.linkedin.com/pulse/kimura-disease-afreen-khan
https://www.linkedin.com/posts/afreen-khan-3528a3b3_kikuchi-necrotizing-sle-activity-6758077476074876928-8fw1
https://rb.gy/keovsg
https://khan-hematopathology-2021.blogspot.com/2021/01/hereditary-spherocytosis.html
https://khan-pathology-2021.blogspot.com/
https://khan-hematopathology-2021.blogspot.com/
https://rb.gy/l44a4v
https://rb.gy/ypx8iq
https://rb.gy/eaipyq
https://9c298etz1jfovarwzavjn02i3l.hop.clickbank.net/
https://rb.gy/xpy7mz
https://rb.gy/egazss
https://cdd2bdl2yjesn8sy3dsiteqa40.hop.clickbank.net/
https://rb.gy/tcb2mp
https://rb.gy/tcb2mp
https://rb.gy/ftztml
https://rb.gy/uhqzwv
https://rb.gy/jg0eth
https://rb.gy/ezfmlp
https://rb.gy/bpzucl
https://rb.gy/bsueld
https://9c298etz1jfovarwzavjn02i3l.hop.clickbank.net/
https://rb.gy/os5asi
I'm not here to teach lessons of pathology which is been done by many people on YouTube and many webinars have been conducted in this pandemic so this is a unique platform of it's kind to help exam going pathology students(MBBS/RESIDENTS/FELLOWS) to excel their university exams..to provide those 10 headings/key points which every student wants to revise on the day of exam, even every examiner expects those points to be represented in the paper to give maximum marks..will try to provide maximum information in the form of flow charts,diagrams,tables and images which are easy to review and represent in the exam..last but not the least the senior consultants/faculty /examiners/guides can refresh/update their knowledge with the advancing world of pathology by simply spending couple of minutes on the video.
Here's my sample pathology report template for AFX vs pleomorphic dermal sarcoma: https://kikoxp.com/posts/5193. A complete organized library of all my videos, ...
Here's my sample pathology report template for AFX vs pleomorphic dermal sarcoma: https://kikoxp.com/posts/5193. A complete organized library of all my videos, digital slides, pics, & sample pathology reports is available here: https://kikoxp.com/posts/5084 (dermpath) & https://kikoxp.com/posts/5083 (bone/soft tissue sarcoma pathology).
This video from 2016 discusses the basic workup of a pleomorphic malignant cutaneous spindle cell tumor. The main differential diagnosis includes spindle cell melanoma, spindle cell squamous cell carcinoma, and atypical fibroxanthoma (AFX). Other entities in the differential include leiomyosarcoma, spindle cell angiosarcoma, and (very rarely) cutaneous rhabdomyosarcoma. A panel of S100 protein (or SOX-10), p63/p40 (and/or cytokeratins), desmin, and ERG (or CD31) can essentially exclude most of those entities, leaving only AFX. Some pathologists like to use CD68, CD10, or vimentin as positive stains for AFX. I do not personally like those stains as they are very non-specific and will stain many different tumors, including spindle cell melanoma, spindle cell squamous cell carcinoma, angiosarcoma, and many other tumors. AFX looks histologically identical to undifferentiated pleomorphic sarcoma (UPS...formerly known as MFH). The only way to distinguish between them is to determine the depth of invasion. If the tumor is confined to the dermis, then it has a very low chance of metastasis and is usually regarded as AFX. If it extends into the subcutis, then it likely has metastatic potential and should be considered as a sarcoma. For undifferentiated pleomorphic sarcomas that are confined to the dermis and subcutis on the head and neck of elderly patients, we usually use the term "pleomorphic dermal sarcoma". These may have a slightly lower metastatic potential than large deep undifferentiated pleomorphic sarcomas but can still behave aggressively.
Please check out my Soft Tissue Pathology & Dermatopathology survival guide textbooks: http://bit.ly/2Te2haB
This video is geared towards medical students, pathology or dermatology residents, or practicing pathologists or dermatologists. Of course, this video is for educational purposes only and is not formal medical advice or consultation.
Presented by Jerad M. Gardner, MD. Please subscribe to my channel to be notified of new pathology teaching videos.
Follow me on:
Snapchat: JMGardnerMD
Twitter: @JMGardnerMD
Instagram: @JMGardnerMD
Kiko: https://kikoxp.com/profile/jerad_gardner1/content?filter=popular
Facebook: https://www.facebook.com/JMGardnerMD/
Please check out my Soft Tissue Pathology & Dermatopathology survival guide textbooks: http://bit.ly/2Te2haB
This video is geared towards medical students, pathology or dermatology residents, or practicing pathologists or dermatologists. Of course, this video is for educational purposes only and is not formal medical advice or consultation.
Presented by Jerad M. Gardner, MD. Please subscribe to my channel to be notified of new pathology teaching videos.
Follow me on:
Snapchat: JMGardnerMD
Twitter: @JMGardnerMD
Instagram: @JMGardnerMD
Kiko: https://kikoxp.com/profile/jerad_gardner1/content?filter=popular
Facebook: https://www.facebook.com/JMGardnerMD/
Here's my sample pathology report template for AFX vs pleomorphic dermal sarcoma: https://kikoxp.com/posts/5193. A complete organized library of all my videos, digital slides, pics, & sample pathology reports is available here: https://kikoxp.com/posts/5084 (dermpath) & https://kikoxp.com/posts/5083 (bone/soft tissue sarcoma pathology).
This video from 2016 discusses the basic workup of a pleomorphic malignant cutaneous spindle cell tumor. The main differential diagnosis includes spindle cell melanoma, spindle cell squamous cell carcinoma, and atypical fibroxanthoma (AFX). Other entities in the differential include leiomyosarcoma, spindle cell angiosarcoma, and (very rarely) cutaneous rhabdomyosarcoma. A panel of S100 protein (or SOX-10), p63/p40 (and/or cytokeratins), desmin, and ERG (or CD31) can essentially exclude most of those entities, leaving only AFX. Some pathologists like to use CD68, CD10, or vimentin as positive stains for AFX. I do not personally like those stains as they are very non-specific and will stain many different tumors, including spindle cell melanoma, spindle cell squamous cell carcinoma, angiosarcoma, and many other tumors. AFX looks histologically identical to undifferentiated pleomorphic sarcoma (UPS...formerly known as MFH). The only way to distinguish between them is to determine the depth of invasion. If the tumor is confined to the dermis, then it has a very low chance of metastasis and is usually regarded as AFX. If it extends into the subcutis, then it likely has metastatic potential and should be considered as a sarcoma. For undifferentiated pleomorphic sarcomas that are confined to the dermis and subcutis on the head and neck of elderly patients, we usually use the term "pleomorphic dermal sarcoma". These may have a slightly lower metastatic potential than large deep undifferentiated pleomorphic sarcomas but can still behave aggressively.
Please check out my Soft Tissue Pathology & Dermatopathology survival guide textbooks: http://bit.ly/2Te2haB
This video is geared towards medical students, pathology or dermatology residents, or practicing pathologists or dermatologists. Of course, this video is for educational purposes only and is not formal medical advice or consultation.
Presented by Jerad M. Gardner, MD. Please subscribe to my channel to be notified of new pathology teaching videos.
Follow me on:
Snapchat: JMGardnerMD
Twitter: @JMGardnerMD
Instagram: @JMGardnerMD
Kiko: https://kikoxp.com/profile/jerad_gardner1/content?filter=popular
Facebook: https://www.facebook.com/JMGardnerMD/
Please check out my Soft Tissue Pathology & Dermatopathology survival guide textbooks: http://bit.ly/2Te2haB
This video is geared towards medical students, pathology or dermatology residents, or practicing pathologists or dermatologists. Of course, this video is for educational purposes only and is not formal medical advice or consultation.
Presented by Jerad M. Gardner, MD. Please subscribe to my channel to be notified of new pathology teaching videos.
Follow me on:
Snapchat: JMGardnerMD
Twitter: @JMGardnerMD
Instagram: @JMGardnerMD
Kiko: https://kikoxp.com/profile/jerad_gardner1/content?filter=popular
Facebook: https://www.facebook.com/JMGardnerMD/
Dr. Michael Alan Hernandez tackles the causes and treatment for spindle cell sarcoma. Fuda Cancer Hospital Dr. Mu Feng talks about the telltale signs and sympto...
Dr. Michael Alan Hernandez tackles the causes and treatment for spindle cell sarcoma. Fuda Cancer Hospital Dr. Mu Feng talks about the telltale signs and symptoms, and treatment for soft tissue sarcoma.
For more Salamat Dok videos, click the link below:
https://www.youtube.com/watch?v=AmPbO5C5Fkw&list=PLgyY1WylJUmh4e4yWhmg57VlzI9hf0xmB
To watch Mission Possible videos, click the link below:
https://www.youtube.com/playlist?list=PLgyY1WylJUmgD28BO6j_rU5FOUW2WeyFS
To watch Matanglawin videos, click link below:
https://www.youtube.com/playlist?list=PLgyY1WylJUmjr1WJSMOegDYXmHBa20_oZ
Subscribe to the ABS-CBN News channel! - http://bit.ly/TheABSCBNNews
Watch the full episodes of Salamat Dok on TFC.TV
http://bit.ly/SalamatDok-TFCTV
and on iWant for Philippine viewers, click:
http://bit.ly/SalamatDok-iWant
Visit our website at http://news.abs-cbn.com
Facebook: https://www.facebook.com/abscbnNEWS
Twitter: https://twitter.com/abscbnnews
#SalamatDok
#ABSCBNNews
Dr. Michael Alan Hernandez tackles the causes and treatment for spindle cell sarcoma. Fuda Cancer Hospital Dr. Mu Feng talks about the telltale signs and symptoms, and treatment for soft tissue sarcoma.
For more Salamat Dok videos, click the link below:
https://www.youtube.com/watch?v=AmPbO5C5Fkw&list=PLgyY1WylJUmh4e4yWhmg57VlzI9hf0xmB
To watch Mission Possible videos, click the link below:
https://www.youtube.com/playlist?list=PLgyY1WylJUmgD28BO6j_rU5FOUW2WeyFS
To watch Matanglawin videos, click link below:
https://www.youtube.com/playlist?list=PLgyY1WylJUmjr1WJSMOegDYXmHBa20_oZ
Subscribe to the ABS-CBN News channel! - http://bit.ly/TheABSCBNNews
Watch the full episodes of Salamat Dok on TFC.TV
http://bit.ly/SalamatDok-TFCTV
and on iWant for Philippine viewers, click:
http://bit.ly/SalamatDok-iWant
Visit our website at http://news.abs-cbn.com
Facebook: https://www.facebook.com/abscbnNEWS
Twitter: https://twitter.com/abscbnnews
#SalamatDok
#ABSCBNNews
For more information on Cleveland Clinic’s Pathology & Laboratory Medicine Institute, please visit https://cle.clinic/3vmekpI
Pathologist Steven Billings, MD, covers a set of challenging cutaneous spindle cell tumors, emphasizing a practical approach and key histologic features that allow accurate diagnosis.
▶Share this video with others: https://youtu.be/9_cnMlD4PdM
▶Subscribe to learn more about Cleveland Clinic: https://www.youtube.com/user/ClevelandClinic?sub_confirmation=1
A single case review of histology, clinical features, and genetic abnormalities seen in metaplastic carcinoma of the breast - spindle cell carcinoma. Includes routine H&E, CK903 (34BE12), and p63 stains.
This video is for educational purposes only and does not represent or replace medical advice. Please consult your physician if you have questions as a patient. If you are a physician, please ensure you research subjects to ensure you have the most up to date information.
All content presented by KL Roncin, MD, unless otherwise noted. Comments and opinions are my own and are current as of the time the video was taken, unless otherwise noted. Please like and subscribe to my channel to receive notifications on any new pathology content!
Follow Me:
Twitter: @KRoSlideReview
@RoncinMD
FOLLOW ME ON SOCIAL MEDIA AND MY BLOG
https://t.me/EKDINKARAJAPATHOLOGYNOTES
www.linkedin.com/in/afreen-khan-3528a3b3
https://www.facebook.com/yasmeen.khan.12177276
https://twitter.com/khanspathology
https://www.instagram.com/khanspathology/
https://rb.gy/8gv5mm
https://khan-pathology-2021.blogspot.com/2021/01/morphological-changes-in-palcenta-in.html
https://rb.gy/hxyfwr
https://www.linkedin.com/pulse/kimura-disease-afreen-khan
https://www.linkedin.com/posts/afreen-khan-3528a3b3_kikuchi-necrotizing-sle-activity-6758077476074876928-8fw1
https://rb.gy/keovsg
https://khan-hematopathology-2021.blogspot.com/2021/01/hereditary-spherocytosis.html
https://khan-pathology-2021.blogspot.com/
https://khan-hematopathology-2021.blogspot.com/
https://rb.gy/l44a4v
https://rb.gy/ypx8iq
https://rb.gy/eaipyq
https://9c298etz1jfovarwzavjn02i3l.hop.clickbank.net/
https://rb.gy/xpy7mz
https://rb.gy/egazss
https://cdd2bdl2yjesn8sy3dsiteqa40.hop.clickbank.net/
https://rb.gy/tcb2mp
https://rb.gy/tcb2mp
https://rb.gy/ftztml
https://rb.gy/uhqzwv
https://rb.gy/jg0eth
https://rb.gy/ezfmlp
https://rb.gy/bpzucl
https://rb.gy/bsueld
https://9c298etz1jfovarwzavjn02i3l.hop.clickbank.net/
https://rb.gy/os5asi
I'm not here to teach lessons of pathology which is been done by many people on YouTube and many webinars have been conducted in this pandemic so this is a unique platform of it's kind to help exam going pathology students(MBBS/RESIDENTS/FELLOWS) to excel their university exams..to provide those 10 headings/key points which every student wants to revise on the day of exam, even every examiner expects those points to be represented in the paper to give maximum marks..will try to provide maximum information in the form of flow charts,diagrams,tables and images which are easy to review and represent in the exam..last but not the least the senior consultants/faculty /examiners/guides can refresh/update their knowledge with the advancing world of pathology by simply spending couple of minutes on the video.
Here's my sample pathology report template for AFX vs pleomorphic dermal sarcoma: https://kikoxp.com/posts/5193. A complete organized library of all my videos, digital slides, pics, & sample pathology reports is available here: https://kikoxp.com/posts/5084 (dermpath) & https://kikoxp.com/posts/5083 (bone/soft tissue sarcoma pathology).
This video from 2016 discusses the basic workup of a pleomorphic malignant cutaneous spindle cell tumor. The main differential diagnosis includes spindle cell melanoma, spindle cell squamous cell carcinoma, and atypical fibroxanthoma (AFX). Other entities in the differential include leiomyosarcoma, spindle cell angiosarcoma, and (very rarely) cutaneous rhabdomyosarcoma. A panel of S100 protein (or SOX-10), p63/p40 (and/or cytokeratins), desmin, and ERG (or CD31) can essentially exclude most of those entities, leaving only AFX. Some pathologists like to use CD68, CD10, or vimentin as positive stains for AFX. I do not personally like those stains as they are very non-specific and will stain many different tumors, including spindle cell melanoma, spindle cell squamous cell carcinoma, angiosarcoma, and many other tumors. AFX looks histologically identical to undifferentiated pleomorphic sarcoma (UPS...formerly known as MFH). The only way to distinguish between them is to determine the depth of invasion. If the tumor is confined to the dermis, then it has a very low chance of metastasis and is usually regarded as AFX. If it extends into the subcutis, then it likely has metastatic potential and should be considered as a sarcoma. For undifferentiated pleomorphic sarcomas that are confined to the dermis and subcutis on the head and neck of elderly patients, we usually use the term "pleomorphic dermal sarcoma". These may have a slightly lower metastatic potential than large deep undifferentiated pleomorphic sarcomas but can still behave aggressively.
Please check out my Soft Tissue Pathology & Dermatopathology survival guide textbooks: http://bit.ly/2Te2haB
This video is geared towards medical students, pathology or dermatology residents, or practicing pathologists or dermatologists. Of course, this video is for educational purposes only and is not formal medical advice or consultation.
Presented by Jerad M. Gardner, MD. Please subscribe to my channel to be notified of new pathology teaching videos.
Follow me on:
Snapchat: JMGardnerMD
Twitter: @JMGardnerMD
Instagram: @JMGardnerMD
Kiko: https://kikoxp.com/profile/jerad_gardner1/content?filter=popular
Facebook: https://www.facebook.com/JMGardnerMD/
Please check out my Soft Tissue Pathology & Dermatopathology survival guide textbooks: http://bit.ly/2Te2haB
This video is geared towards medical students, pathology or dermatology residents, or practicing pathologists or dermatologists. Of course, this video is for educational purposes only and is not formal medical advice or consultation.
Presented by Jerad M. Gardner, MD. Please subscribe to my channel to be notified of new pathology teaching videos.
Follow me on:
Snapchat: JMGardnerMD
Twitter: @JMGardnerMD
Instagram: @JMGardnerMD
Kiko: https://kikoxp.com/profile/jerad_gardner1/content?filter=popular
Facebook: https://www.facebook.com/JMGardnerMD/
Dr. Michael Alan Hernandez tackles the causes and treatment for spindle cell sarcoma. Fuda Cancer Hospital Dr. Mu Feng talks about the telltale signs and symptoms, and treatment for soft tissue sarcoma.
For more Salamat Dok videos, click the link below:
https://www.youtube.com/watch?v=AmPbO5C5Fkw&list=PLgyY1WylJUmh4e4yWhmg57VlzI9hf0xmB
To watch Mission Possible videos, click the link below:
https://www.youtube.com/playlist?list=PLgyY1WylJUmgD28BO6j_rU5FOUW2WeyFS
To watch Matanglawin videos, click link below:
https://www.youtube.com/playlist?list=PLgyY1WylJUmjr1WJSMOegDYXmHBa20_oZ
Subscribe to the ABS-CBN News channel! - http://bit.ly/TheABSCBNNews
Watch the full episodes of Salamat Dok on TFC.TV
http://bit.ly/SalamatDok-TFCTV
and on iWant for Philippine viewers, click:
http://bit.ly/SalamatDok-iWant
Visit our website at http://news.abs-cbn.com
Facebook: https://www.facebook.com/abscbnNEWS
Twitter: https://twitter.com/abscbnnews
#SalamatDok
#ABSCBNNews
Spindle cell carcinoma is a type of cancer that begins in the skin or in tissues that line or cover internal organs and that contains long spindle-shaped cells. Also called sarcomatoid carcinoma.
This process results in cancer cell death while sparing the noncancerous tissue ... Non-Small Cell Lung* ... Squamous Cell Carcinoma ... ** Desmoplastic small round cell sarcoma, myxofibrosarcoma, pleomorphic sarcoma, and pleomorphic spindle cell sarcoma .
This process results in cancer cell death while sparing the noncancerous tissue ...Adenoid Cystic Carcinoma ... SquamousCell Carcinoma ... ** Desmoplastic small round cell sarcoma, myxofibrosarcoma, pleomorphic sarcoma, and pleomorphic spindle cell sarcoma.