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Dune: Part Two | Official Trailer
Long Live the Fighters. #DunePartTwo only in theaters March 15.
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https://www.instagram.com/dunemovie/
https://www.facebook.com/dune
https://twitter.com/dunemovie
https://www.tiktok.com/@dunemovie
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The saga continues as award-winning filmmaker Denis Villeneuve embarks on “Dune: Part Two,” the next chapter of Frank Herbert’s celebrated novel Dune, with an expanded all-star international ensemble cast. The film, from Warner Bros. Pictures and Legendary Pictures, is the highly anticipated follow-up to 2021’s six-time Academy Award-winning “Dune.”
The big-screen epic continues the adaptation of Frank Herbert’s acclaimed bestseller Dune with returning and new stars, including Oscar nominee Timothée Chalamet (“Wonka,” “Call Me by Your Name”), Zendaya (“Spider...
published: 03 May 2023
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Dune: Part Two | Official Trailer 3
You are not prepared for what is to come. #DunePartTwo - Only in theaters March 1. Tickets are on sale NOW. https://fandan.co/Dune
The saga continues as award-winning filmmaker Denis Villeneuve embarks on “Dune: Part Two,” the next chapter of Frank Herbert’s celebrated novel Dune, with an expanded all-star international ensemble cast. The film, from Warner Bros. Pictures and Legendary Pictures, is the highly anticipated follow-up to 2021’s six-time Academy Award-winning “Dune.”
The big-screen epic continues the adaptation of Frank Herbert’s acclaimed bestseller Dune with returning and new stars, including Oscar nominee Timothée Chalamet (“Wonka,” “Call Me by Your Name”), Zendaya (“Spider-Man: No Way Home,” “Malcolm & Marie,” “Euphoria”), Rebecca Ferguson (“Mission: Impossible – Dead Reck...
published: 12 Dec 2023
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Dune: Part Two | Official Trailer 2
Do what must be done. #DunePartTwo only in theaters March 15.
DUNE: PART TWO
The saga continues as award-winning filmmaker Denis Villeneuve embarks on “Dune: Part Two,” the next chapter of Frank Herbert’s celebrated novel Dune, with an expanded all-star international ensemble cast. The film, from Warner Bros. Pictures and Legendary Pictures, is the highly anticipated follow-up to 2021’s six-time Academy Award-winning “Dune.”
The big-screen epic continues the adaptation of Frank Herbert’s acclaimed bestseller Dune with returning and new stars, including Oscar nominee Timothée Chalamet (“Wonka,” “Call Me by Your Name”), Zendaya (“Spider-Man: No Way Home,” “Malcolm & Marie,” “Euphoria”), Rebecca Ferguson (“Mission: Impossible – Dead Reckoning”), Oscar nominee Josh Brolin (“Avengers: End Ga...
published: 29 Jun 2023
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DUNE PART 2 - Denis Villeneuve On The Ending Change
Denis Villeneuve On the Dune Part 2 ending change. In this video essay, I discuss the ending of Denis Villeneuve's Dune Part 2 and why Denis Villeneuve made some changes. The ending scene with Paul Atreides as the new Emperor and Chani leaving, sets up a Dune Messiah movie in an interesting way. There are heavy spoilers in this video.
Paul Atreides leads nomadic tribes in a battle to control the desert planet Arrakis. Dune is an upcoming epic science fiction film directed by Denis Villeneuve with a screenplay by Jon Spaihts, Villeneuve, and Eric Roth. The film is an international co-production of Canada, Hungary, the United Kingdom, and the United States. It is the first of a planned two-part adaptation of the 1965 novel of the same name by Frank Herbert, which will cover roughly the firs...
published: 15 Jun 2024
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skibidi toilet 73 (part 2)
titans confront g-toilet
full-screen version
Respectful assets used in the video:
suits - https://steamcommunity.com/sharedfiles/filedetails/?id=2849230339
speakers models by ivip -https://steamcommunity.com/sharedfiles/filedetails/?id=2680336465
https://steamcommunity.com/sharedfiles/filedetails/?id=2684729253
map - https://steamcommunity.com/sharedfiles/filedetails/?id=1958007290
additional particles by @HoovyTube
Contact me:
instagram.com/dafuqboomtv
blugrayguy@gmail.com
published: 03 May 2024
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PART 2 | IDOL RAFFY, NALUHA SA KASO NG MOVE IT RIDER NA NAPAGBINTANGANG HOLDAPER!
PART 1: https://youtu.be/e_9fxd0NsZQ
⚠️PARA SA INYONG MGA SUMBONG AT REKLAMO ⚠️
Maaari po kayong magtungo sa ACTION CENTER ng RAFFY TULFO IN ACTION sa TV5 Media Center, Reliance Cor. Sheridan St., Mandaluyong mul a 9:00AM-3:00PM, tuwing Lunes hanggang Biyernes. Mangyari lamang po na magdala ng vaccination card at huwag nang magsama ng bata. Kung kayo naman ay senior citizen o may karamdaman, magpadala na lamang po kayo ng inyong representative sa aming tanggapan. Gaya po ng aming paalala, LIBRE at WALA PONG BAYAD ang serbisyong aming ibinibigay kaya 'wag na 'wag po kayong magpapaloko sa mga scammers na mangangako na pauunahin kayo sa pila at maniningil ng bayad.
#RTIA #TULFO #IDOLRAFFY #SENATORRAFFY #WANTEDSARADYO
#SUMBONGATAKSYON #RAFFYTULFO #RAFFY #TULFO #RAFFYTULFOINACTION #WSR #TULF...
published: 06 Jun 2024
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Rebel Moon — Part Two: The Scargiver | Official Trailer | Netflix
REBEL MOON — PART TWO: THE SCARGIVER premieres on Netflix April 19, 2024.
REBEL MOON — PART TWO: THE SCARGIVER continues the epic saga of Kora and the surviving warriors as they prepare to sacrifice everything, fighting alongside the brave people of Veldt, to defend a once peaceful village, a newfound homeland for those who have lost their own in the fight against the Motherworld. On the eve of their battle the warriors must face the truths of their own pasts, each revealing why they fight. As the full force of the Realm bears down on the burgeoning rebellion, unbreakable bonds are forged, heroes emerge, and legends are made.
From Zack Snyder, the filmmaker behind 300, Man of Steel, and Army of the Dead, REBEL MOON is a 2-part movie event decades in the making.
REBEL MOON — PART ONE: A ...
published: 18 Mar 2024
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the skibidi wars 104 (part 2)
titans arrive to try and regain control of sonar titan.
special thanks to @HoovyTube for custom particles!
original concept by @DaFuqBoom
skibidi dop dop dop yes yes
this is the continuation of the Skibidi Wars series.
full-screen version
skibidi wars S24 E04
Join my Official Discord Server: https://discord.gg/virlance
Become member of my channel here for access to exclusive gadgets, behind the scenes, exclusive sneak peeks and much more:
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This series is not the original skibidi toilet series, but a fan made version that features an alternate plot line of the skibidi toilet series. All videos are created solely by me.
published: 15 Jun 2024
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Man Wants His Two Mercedes Back! I Part 2
Jorge claims former business partner George sold two vehicles that belong to him for parts, but George says they’re inoperable.
The Original! There’s only ONE Judge Judy. Visit our website for where to watch, weekdays.
Subscribe to Judge Judy on YouTube: https://www.youtube.com/channel/UCzMPPxbQG6iZttQhq3ukXSg?sub_confirmation=1
#JudgeJudy
published: 14 Jun 2024
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Dune Part Two FULL Breakdown, Easter Eggs and Ending Explained
Dune Part Two. Paul Atriedes Becomes A God Kwisatz Haderach Ending Explained. Paul Atriedes vs Feyd. Lore & History, Dune Messiah Dune 3 Teaser Trailer, Alia Explained & Kwisatz Haderach Powers ► https://bit.ly/AwesomeSubscribe
Henry Cavill Joins The Marvel Universe https://www.youtube.com/watch?v=ObnVqcD1qC0&list=PLOIeYdZ3QczwWT3yd94Xc6n-ooI85uV_u&index=1&pp=gAQBiAQB
Moon Knight Season 2 Teaser https://www.youtube.com/watch?v=HJew806Gx6c&list=PLOIeYdZ3QczxQXxyV_2D8kuEs_QsuQIyJ&index=1&pp=gAQBiAQB
Venom 3 Teaser https://www.youtube.com/watch?v=ZJDuVz4C__M&list=PLOIeYdZ3QczxQXxyV_2D8kuEs_QsuQIyJ&index=2&pp=gAQBiAQB
Deadpool and Wolverine Trailer https://www.youtube.com/watch?v=xSALmuCG0YE&list=PLOIeYdZ3QczwWT3yd94Xc6n-ooI85uV_u&index=1
Fantastic Four Teaser https://www.youtube.com/watch?v=Q...
published: 02 Mar 2024
2:25
Dune: Part Two | Official Trailer
Long Live the Fighters. #DunePartTwo only in theaters March 15.
-----------------
https://www.instagram.com/dunemovie/
https://www.facebook.com/dune
https://tw...
Long Live the Fighters. #DunePartTwo only in theaters March 15.
-----------------
https://www.instagram.com/dunemovie/
https://www.facebook.com/dune
https://twitter.com/dunemovie
https://www.tiktok.com/@dunemovie
-----------------
The saga continues as award-winning filmmaker Denis Villeneuve embarks on “Dune: Part Two,” the next chapter of Frank Herbert’s celebrated novel Dune, with an expanded all-star international ensemble cast. The film, from Warner Bros. Pictures and Legendary Pictures, is the highly anticipated follow-up to 2021’s six-time Academy Award-winning “Dune.”
The big-screen epic continues the adaptation of Frank Herbert’s acclaimed bestseller Dune with returning and new stars, including Oscar nominee Timothée Chalamet (“Wonka,” “Call Me by Your Name”), Zendaya (“Spider-Man: No Way Home,” “Malcolm & Marie,” “Euphoria”), Rebecca Ferguson (“Mission: Impossible – Dead Reckoning”), Oscar nominee Josh Brolin (“Avengers: End Game,” “Milk”), Oscar nominee Austin Butler (“Elvis,” “Once Upon A Time…In Hollywood”), Oscar nominee Florence Pugh (“Black Widow,” “Little Women”), Dave Bautista (the “Guardians of the Galaxy” films, “Thor: Love and Thunder”), Oscar winner Christopher Walken (“The Deer Hunter,” “Hairspray”), Stephen McKinley Henderson (“Fences,” “Lady Bird”), Léa Seydoux (the “James Bond” franchise and “Crimes of the Future”), with Stellan Skarsgård (the “Mamma Mia!” films, “Avengers: Age of Ultron”), with Oscar nominee Charlotte Rampling (“45 Years,” “Assassin’s Creed”), and Oscar winner Javier Bardem (“No Country for Old Men,” “Being the Ricardos”).
“Dune: Part Two” will explore the mythic journey of Paul Atreides as he unites with Chani and the Fremen while on a warpath of revenge against the conspirators who destroyed his family. Facing a choice between the love of his life and the fate of the known universe, he endeavors to prevent a terrible future only he can foresee.
Villeneuve directed from a screenplay he co-wrote with Jon Spaihts based on Herbert’s novel. The film is produced by Mary Parent, Cale Boyter, Villeneuve, Tanya Lapointe and Patrick McCormick. The executive producers are Josh Grode, Herbert W. Gains, Jon Spaihts, Thomas Tull, Brian Herbert, Byron Merritt, Kim Herbert, with Kevin J. Anderson serving as creative consultant.
Villeneuve is again collaborating with his “Dune” creatives: Oscar-winning director of photography Greig Fraser; Oscar-winning production designer Patrice Vermette; Oscar-winning editor Joe Walker; Oscar-winning visual effects supervisor Paul Lambert; Oscar-nominated costume designer Jacqueline West. Oscar-winning composer Hans Zimmer is again on hand to create the score.
“Dune: Part Two” was filmed on location in Budapest, Abu Dhabi, Jordan and Italy. The film is slated for a March 15, 2024 worldwide release from Warner Bros. Pictures.
https://wn.com/Dune_Part_Two_|_Official_Trailer
Long Live the Fighters. #DunePartTwo only in theaters March 15.
-----------------
https://www.instagram.com/dunemovie/
https://www.facebook.com/dune
https://twitter.com/dunemovie
https://www.tiktok.com/@dunemovie
-----------------
The saga continues as award-winning filmmaker Denis Villeneuve embarks on “Dune: Part Two,” the next chapter of Frank Herbert’s celebrated novel Dune, with an expanded all-star international ensemble cast. The film, from Warner Bros. Pictures and Legendary Pictures, is the highly anticipated follow-up to 2021’s six-time Academy Award-winning “Dune.”
The big-screen epic continues the adaptation of Frank Herbert’s acclaimed bestseller Dune with returning and new stars, including Oscar nominee Timothée Chalamet (“Wonka,” “Call Me by Your Name”), Zendaya (“Spider-Man: No Way Home,” “Malcolm & Marie,” “Euphoria”), Rebecca Ferguson (“Mission: Impossible – Dead Reckoning”), Oscar nominee Josh Brolin (“Avengers: End Game,” “Milk”), Oscar nominee Austin Butler (“Elvis,” “Once Upon A Time…In Hollywood”), Oscar nominee Florence Pugh (“Black Widow,” “Little Women”), Dave Bautista (the “Guardians of the Galaxy” films, “Thor: Love and Thunder”), Oscar winner Christopher Walken (“The Deer Hunter,” “Hairspray”), Stephen McKinley Henderson (“Fences,” “Lady Bird”), Léa Seydoux (the “James Bond” franchise and “Crimes of the Future”), with Stellan Skarsgård (the “Mamma Mia!” films, “Avengers: Age of Ultron”), with Oscar nominee Charlotte Rampling (“45 Years,” “Assassin’s Creed”), and Oscar winner Javier Bardem (“No Country for Old Men,” “Being the Ricardos”).
“Dune: Part Two” will explore the mythic journey of Paul Atreides as he unites with Chani and the Fremen while on a warpath of revenge against the conspirators who destroyed his family. Facing a choice between the love of his life and the fate of the known universe, he endeavors to prevent a terrible future only he can foresee.
Villeneuve directed from a screenplay he co-wrote with Jon Spaihts based on Herbert’s novel. The film is produced by Mary Parent, Cale Boyter, Villeneuve, Tanya Lapointe and Patrick McCormick. The executive producers are Josh Grode, Herbert W. Gains, Jon Spaihts, Thomas Tull, Brian Herbert, Byron Merritt, Kim Herbert, with Kevin J. Anderson serving as creative consultant.
Villeneuve is again collaborating with his “Dune” creatives: Oscar-winning director of photography Greig Fraser; Oscar-winning production designer Patrice Vermette; Oscar-winning editor Joe Walker; Oscar-winning visual effects supervisor Paul Lambert; Oscar-nominated costume designer Jacqueline West. Oscar-winning composer Hans Zimmer is again on hand to create the score.
“Dune: Part Two” was filmed on location in Budapest, Abu Dhabi, Jordan and Italy. The film is slated for a March 15, 2024 worldwide release from Warner Bros. Pictures.
- published: 03 May 2023
- views: 29616576
2:40
Dune: Part Two | Official Trailer 3
You are not prepared for what is to come. #DunePartTwo - Only in theaters March 1. Tickets are on sale NOW. https://fandan.co/Dune
The saga continues as award-...
You are not prepared for what is to come. #DunePartTwo - Only in theaters March 1. Tickets are on sale NOW. https://fandan.co/Dune
The saga continues as award-winning filmmaker Denis Villeneuve embarks on “Dune: Part Two,” the next chapter of Frank Herbert’s celebrated novel Dune, with an expanded all-star international ensemble cast. The film, from Warner Bros. Pictures and Legendary Pictures, is the highly anticipated follow-up to 2021’s six-time Academy Award-winning “Dune.”
The big-screen epic continues the adaptation of Frank Herbert’s acclaimed bestseller Dune with returning and new stars, including Oscar nominee Timothée Chalamet (“Wonka,” “Call Me by Your Name”), Zendaya (“Spider-Man: No Way Home,” “Malcolm & Marie,” “Euphoria”), Rebecca Ferguson (“Mission: Impossible – Dead Reckoning”), Oscar nominee Josh Brolin (“Avengers: End Game,” “Milk”), Oscar nominee Austin Butler (“Elvis,” “Once Upon A Time…In Hollywood”), Oscar nominee Florence Pugh (“Black Widow,” “Little Women”), Dave Bautista (the “Guardians of the Galaxy” films, “Thor: Love and Thunder”), Oscar winner Christopher Walken (“The Deer Hunter,” “Hairspray”), Léa Seydoux (the “James Bond” franchise and “Crimes of the Future”), Souheila Yacoub (“The Braves,” “Climax”), with Stellan Skarsgård (the “Mamma Mia!” films, “Avengers: Age of Ultron”), with Oscar nominee Charlotte Rampling (“45 Years,” “Assassin’s Creed”), and Oscar winner Javier Bardem (“No Country for Old Men,” “Being the Ricardos”).
“Dune: Part Two” will explore the mythic journey of Paul Atreides as he unites with Chani and the Fremen while on a path of revenge against the conspirators who destroyed his family. Facing a choice between the love of his life and the fate of the known universe, he endeavors to prevent a terrible future only he can foresee.
Villeneuve directed from a screenplay he co-wrote with Jon Spaihts based on Herbert’s novel. The film is produced by Mary Parent, Cale Boyter, Villeneuve, Tanya Lapointe and Patrick McCormick. The executive producers are Joshua Grode, Herbert W. Gains, Jon Spaihts, Thomas Tull, Brian Herbert, Byron Merritt, Kim Herbert, with Kevin J. Anderson serving as creative consultant.
Villeneuve is again collaborating with his “Dune” creatives: Oscar-winning director of photography Greig Fraser; Oscar-winning production designer Patrice Vermette; Oscar-winning editor Joe Walker; Oscar-winning visual effects supervisor Paul Lambert; Oscar-nominated costume designer Jacqueline West. Oscar-winning composer Hans Zimmer is again on hand to create the score.
Warner Bros. Pictures and Legendary Pictures Present A Legendary Pictures Production, A Film By Denis Villeneuve, “Dune: Part Two.” The film is slated for a March 1, 2024 release in theaters and IMAX nationwide and internationally beginning on 28 February 2024, distributed by Warner Bros. Pictures.
https://wn.com/Dune_Part_Two_|_Official_Trailer_3
You are not prepared for what is to come. #DunePartTwo - Only in theaters March 1. Tickets are on sale NOW. https://fandan.co/Dune
The saga continues as award-winning filmmaker Denis Villeneuve embarks on “Dune: Part Two,” the next chapter of Frank Herbert’s celebrated novel Dune, with an expanded all-star international ensemble cast. The film, from Warner Bros. Pictures and Legendary Pictures, is the highly anticipated follow-up to 2021’s six-time Academy Award-winning “Dune.”
The big-screen epic continues the adaptation of Frank Herbert’s acclaimed bestseller Dune with returning and new stars, including Oscar nominee Timothée Chalamet (“Wonka,” “Call Me by Your Name”), Zendaya (“Spider-Man: No Way Home,” “Malcolm & Marie,” “Euphoria”), Rebecca Ferguson (“Mission: Impossible – Dead Reckoning”), Oscar nominee Josh Brolin (“Avengers: End Game,” “Milk”), Oscar nominee Austin Butler (“Elvis,” “Once Upon A Time…In Hollywood”), Oscar nominee Florence Pugh (“Black Widow,” “Little Women”), Dave Bautista (the “Guardians of the Galaxy” films, “Thor: Love and Thunder”), Oscar winner Christopher Walken (“The Deer Hunter,” “Hairspray”), Léa Seydoux (the “James Bond” franchise and “Crimes of the Future”), Souheila Yacoub (“The Braves,” “Climax”), with Stellan Skarsgård (the “Mamma Mia!” films, “Avengers: Age of Ultron”), with Oscar nominee Charlotte Rampling (“45 Years,” “Assassin’s Creed”), and Oscar winner Javier Bardem (“No Country for Old Men,” “Being the Ricardos”).
“Dune: Part Two” will explore the mythic journey of Paul Atreides as he unites with Chani and the Fremen while on a path of revenge against the conspirators who destroyed his family. Facing a choice between the love of his life and the fate of the known universe, he endeavors to prevent a terrible future only he can foresee.
Villeneuve directed from a screenplay he co-wrote with Jon Spaihts based on Herbert’s novel. The film is produced by Mary Parent, Cale Boyter, Villeneuve, Tanya Lapointe and Patrick McCormick. The executive producers are Joshua Grode, Herbert W. Gains, Jon Spaihts, Thomas Tull, Brian Herbert, Byron Merritt, Kim Herbert, with Kevin J. Anderson serving as creative consultant.
Villeneuve is again collaborating with his “Dune” creatives: Oscar-winning director of photography Greig Fraser; Oscar-winning production designer Patrice Vermette; Oscar-winning editor Joe Walker; Oscar-winning visual effects supervisor Paul Lambert; Oscar-nominated costume designer Jacqueline West. Oscar-winning composer Hans Zimmer is again on hand to create the score.
Warner Bros. Pictures and Legendary Pictures Present A Legendary Pictures Production, A Film By Denis Villeneuve, “Dune: Part Two.” The film is slated for a March 1, 2024 release in theaters and IMAX nationwide and internationally beginning on 28 February 2024, distributed by Warner Bros. Pictures.
- published: 12 Dec 2023
- views: 21752236
3:04
Dune: Part Two | Official Trailer 2
Do what must be done. #DunePartTwo only in theaters March 15.
DUNE: PART TWO
The saga continues as award-winning filmmaker Denis Villeneuve embarks on “Dune: ...
Do what must be done. #DunePartTwo only in theaters March 15.
DUNE: PART TWO
The saga continues as award-winning filmmaker Denis Villeneuve embarks on “Dune: Part Two,” the next chapter of Frank Herbert’s celebrated novel Dune, with an expanded all-star international ensemble cast. The film, from Warner Bros. Pictures and Legendary Pictures, is the highly anticipated follow-up to 2021’s six-time Academy Award-winning “Dune.”
The big-screen epic continues the adaptation of Frank Herbert’s acclaimed bestseller Dune with returning and new stars, including Oscar nominee Timothée Chalamet (“Wonka,” “Call Me by Your Name”), Zendaya (“Spider-Man: No Way Home,” “Malcolm & Marie,” “Euphoria”), Rebecca Ferguson (“Mission: Impossible – Dead Reckoning”), Oscar nominee Josh Brolin (“Avengers: End Game,” “Milk”), Oscar nominee Austin Butler (“Elvis,” “Once Upon A Time...In Hollywood”), Oscar nominee Florence Pugh (“Black Widow,” “Little Women”), Dave Bautista (the “Guardians of the Galaxy” films, “Thor: Love and Thunder”), Oscar winner Christopher Walken (“The Deer Hunter,” “Hairspray”), Stephen McKinley Henderson (“Fences,” “Lady Bird”), Léa Seydoux (the “James Bond” franchise and “Crimes of the Future”), with Stellan Skarsgård (the “Mamma Mia!” films, “Avengers: Age of Ultron”), with Oscar nominee Charlotte Rampling (“45 Years,” “Assassin’s Creed”), and Oscar winner Javier Bardem (“No Country for Old Men,” “Being the Ricardos”).
“Dune: Part Two” will explore the mythic journey of Paul Atreides as he unites with Chani and the Fremen while on a warpath of revenge against the conspirators who destroyed his family. Facing a choice between the love of his life and the fate of the known universe, he endeavors to prevent a terrible future only he can foresee.
Villeneuve directed from a screenplay he co-wrote with Jon Spaihts based on Herbert’s novel. The film is produced by Mary Parent, Cale Boyter, Villeneuve, Tanya Lapointe and Patrick McCormick. The executive producers are Josh Grode, Herbert W. Gains, Jon Spaihts, Thomas Tull, Brian Herbert, Byron Merritt, Kim Herbert, with Kevin J. Anderson serving as creative consultant.
Villeneuve is again collaborating with his “Dune” creatives: Oscar-winning director of photography Greig Fraser; Oscar-winning production designer Patrice Vermette; Oscar-winning editor Joe Walker; Oscar-winning visual effects supervisor Paul Lambert; Oscar-nominated costume designer Jacqueline West. Oscar-winning composer Hans Zimmer is again on hand to create the score.
“Dune: Part Two” was filmed on location in Budapest, Abu Dhabi, Jordan and Italy. The film is slated for a March 15, 2024 worldwide release from Warner Bros. Pictures.
https://wn.com/Dune_Part_Two_|_Official_Trailer_2
Do what must be done. #DunePartTwo only in theaters March 15.
DUNE: PART TWO
The saga continues as award-winning filmmaker Denis Villeneuve embarks on “Dune: Part Two,” the next chapter of Frank Herbert’s celebrated novel Dune, with an expanded all-star international ensemble cast. The film, from Warner Bros. Pictures and Legendary Pictures, is the highly anticipated follow-up to 2021’s six-time Academy Award-winning “Dune.”
The big-screen epic continues the adaptation of Frank Herbert’s acclaimed bestseller Dune with returning and new stars, including Oscar nominee Timothée Chalamet (“Wonka,” “Call Me by Your Name”), Zendaya (“Spider-Man: No Way Home,” “Malcolm & Marie,” “Euphoria”), Rebecca Ferguson (“Mission: Impossible – Dead Reckoning”), Oscar nominee Josh Brolin (“Avengers: End Game,” “Milk”), Oscar nominee Austin Butler (“Elvis,” “Once Upon A Time...In Hollywood”), Oscar nominee Florence Pugh (“Black Widow,” “Little Women”), Dave Bautista (the “Guardians of the Galaxy” films, “Thor: Love and Thunder”), Oscar winner Christopher Walken (“The Deer Hunter,” “Hairspray”), Stephen McKinley Henderson (“Fences,” “Lady Bird”), Léa Seydoux (the “James Bond” franchise and “Crimes of the Future”), with Stellan Skarsgård (the “Mamma Mia!” films, “Avengers: Age of Ultron”), with Oscar nominee Charlotte Rampling (“45 Years,” “Assassin’s Creed”), and Oscar winner Javier Bardem (“No Country for Old Men,” “Being the Ricardos”).
“Dune: Part Two” will explore the mythic journey of Paul Atreides as he unites with Chani and the Fremen while on a warpath of revenge against the conspirators who destroyed his family. Facing a choice between the love of his life and the fate of the known universe, he endeavors to prevent a terrible future only he can foresee.
Villeneuve directed from a screenplay he co-wrote with Jon Spaihts based on Herbert’s novel. The film is produced by Mary Parent, Cale Boyter, Villeneuve, Tanya Lapointe and Patrick McCormick. The executive producers are Josh Grode, Herbert W. Gains, Jon Spaihts, Thomas Tull, Brian Herbert, Byron Merritt, Kim Herbert, with Kevin J. Anderson serving as creative consultant.
Villeneuve is again collaborating with his “Dune” creatives: Oscar-winning director of photography Greig Fraser; Oscar-winning production designer Patrice Vermette; Oscar-winning editor Joe Walker; Oscar-winning visual effects supervisor Paul Lambert; Oscar-nominated costume designer Jacqueline West. Oscar-winning composer Hans Zimmer is again on hand to create the score.
“Dune: Part Two” was filmed on location in Budapest, Abu Dhabi, Jordan and Italy. The film is slated for a March 15, 2024 worldwide release from Warner Bros. Pictures.
- published: 29 Jun 2023
- views: 26635354
12:38
DUNE PART 2 - Denis Villeneuve On The Ending Change
Denis Villeneuve On the Dune Part 2 ending change. In this video essay, I discuss the ending of Denis Villeneuve's Dune Part 2 and why Denis Villeneuve made som...
Denis Villeneuve On the Dune Part 2 ending change. In this video essay, I discuss the ending of Denis Villeneuve's Dune Part 2 and why Denis Villeneuve made some changes. The ending scene with Paul Atreides as the new Emperor and Chani leaving, sets up a Dune Messiah movie in an interesting way. There are heavy spoilers in this video.
Paul Atreides leads nomadic tribes in a battle to control the desert planet Arrakis. Dune is an upcoming epic science fiction film directed by Denis Villeneuve with a screenplay by Jon Spaihts, Villeneuve, and Eric Roth. The film is an international co-production of Canada, Hungary, the United Kingdom, and the United States. It is the first of a planned two-part adaptation of the 1965 novel of the same name by Frank Herbert, which will cover roughly the first half of the book. The film stars an ensemble cast including Timothée Chalamet, Rebecca Ferguson, Oscar Isaac, Josh Brolin, Stellan Skarsgård, Dave Bautista, Stephen McKinley Henderson, Zendaya, David Dastmalchian, Chang Chen, Sharon Duncan-Brewster, Charlotte Rampling, Jason Momoa, and Javier Bardem.
#Dune #DunePart2 #DuneMovie
DUNE PART 2 Ending: What Will Happen In Dune Messiah?:
https://youtu.be/ohn2DXtXZyA
DUNE MESSIAH - How Denis Villeneuve Will Adapt The Big Moments:
https://youtu.be/CbnR0i2hH_o
DUNE MESSIAH Will Change Movies Forever:
https://youtu.be/uqPqkDCZYxc
Why DUNE PART 2 Is A Masterpiece:
https://youtu.be/axn_AJgPtuM
DUNE PART 2 Review - The Best Sci-Fi Movie Of The Decade:
https://youtu.be/L-3c8Cq5KE8
What I Want From DUNE MESSIAH:
https://youtu.be/ZMIGoLxCWe4
DUNE MESSIAH Officially Confirmed - Release Date Prediction & Sequel News:
https://youtu.be/124ETnfaIo8
The Perfect Scene In DUNE PART 2:
https://youtu.be/nWVLbp8ukLM
DUNE PART 2 Ending Explained (Full Movie Breakdown):
https://youtu.be/Irwa2CDFZ_4
DUNE PART 2 Explained: The Biggest Questions Answered:
https://youtu.be/1yaskq17yiI
DUNE PART 2 Explained: The Meaning Of Paul's Visions:
https://youtu.be/bQXWccYONBc
DUNE PART 2 - Biggest Differences Between The Movie And Book:
https://youtu.be/5d1v1Rcc_2k
DUNE PART 2 Reviews Call It A MASTERPIECE!:
https://youtu.be/IlN8YXf_xG4
DUNE PART 2 Will Change Movies Forever:
https://bit.ly/3J4Su10
DUNE PART 2 - Creating The Ending Scene:
https://youtu.be/OsIGk50-J7Y
DUNE PART 2 - Why Feyd Rautha Can Be A Great Villain:
https://youtu.be/ZgxFvYGJYWU
DUNE PART 2 First 10 Minutes Breakdown (New Footage Description & Details):
https://youtu.be/PrqslqRK6Y4
DUNE PART 2 Trailer Breakdown & Review - The Best Trailer Yet:
https://youtu.be/6WvBqRQ7_iU
DUNE PART 2 Trailer Breakdown & Review - This Looks Like A Masterpiece:
https://bit.ly/3prTgQU
DUNE: The Denis Villeneuve Trilogy:
https://bit.ly/3N7GTmM
Why DUNE Is A Modern Masterpiece:
https://bit.ly/3nyniiu
DUNE Review - The Best Movie Of The Year:
https://bit.ly/3HwpeQF
DUNE Explained: The Biggest Questions Answered:
https://bit.ly/3x33OWk
DUNE Ending Explained (Full Movie Breakdown):
https://bit.ly/3DAMOZY
DUNE PART 2 | Destiny Arrives:
https://youtu.be/fanoWA9o6k0
DUNE: Part Two - Official Trailer:
https://bit.ly/3ASgTo8
DUNE: Part Two - Official Trailer 2:
https://youtu.be/_YUzQa_1RCE
DUNE: Part Two - Official Trailer 3:
https://youtu.be/U2Qp5pL3ovA?si=GFnn1l9Xv4g_HpLh
Timestamps:
0:00 Intro
1:33 Denis Villeneuve On Changing The Dune Part 2 Ending
7:11 How The Dune Part 2 Ending Could Connect To Dune Messiah
Follow Cortex on Social Media:
https://twitter.com/CortexVideos
https://www.facebook.com/CortexVideos
https://www.reddit.com/r/CortexVideos
https://www.instagram.com/CortexVideos
DUNE PART 2 - Denis Villeneuve On The Ending Change
https://wn.com/Dune_Part_2_Denis_Villeneuve_On_The_Ending_Change
Denis Villeneuve On the Dune Part 2 ending change. In this video essay, I discuss the ending of Denis Villeneuve's Dune Part 2 and why Denis Villeneuve made some changes. The ending scene with Paul Atreides as the new Emperor and Chani leaving, sets up a Dune Messiah movie in an interesting way. There are heavy spoilers in this video.
Paul Atreides leads nomadic tribes in a battle to control the desert planet Arrakis. Dune is an upcoming epic science fiction film directed by Denis Villeneuve with a screenplay by Jon Spaihts, Villeneuve, and Eric Roth. The film is an international co-production of Canada, Hungary, the United Kingdom, and the United States. It is the first of a planned two-part adaptation of the 1965 novel of the same name by Frank Herbert, which will cover roughly the first half of the book. The film stars an ensemble cast including Timothée Chalamet, Rebecca Ferguson, Oscar Isaac, Josh Brolin, Stellan Skarsgård, Dave Bautista, Stephen McKinley Henderson, Zendaya, David Dastmalchian, Chang Chen, Sharon Duncan-Brewster, Charlotte Rampling, Jason Momoa, and Javier Bardem.
#Dune #DunePart2 #DuneMovie
DUNE PART 2 Ending: What Will Happen In Dune Messiah?:
https://youtu.be/ohn2DXtXZyA
DUNE MESSIAH - How Denis Villeneuve Will Adapt The Big Moments:
https://youtu.be/CbnR0i2hH_o
DUNE MESSIAH Will Change Movies Forever:
https://youtu.be/uqPqkDCZYxc
Why DUNE PART 2 Is A Masterpiece:
https://youtu.be/axn_AJgPtuM
DUNE PART 2 Review - The Best Sci-Fi Movie Of The Decade:
https://youtu.be/L-3c8Cq5KE8
What I Want From DUNE MESSIAH:
https://youtu.be/ZMIGoLxCWe4
DUNE MESSIAH Officially Confirmed - Release Date Prediction & Sequel News:
https://youtu.be/124ETnfaIo8
The Perfect Scene In DUNE PART 2:
https://youtu.be/nWVLbp8ukLM
DUNE PART 2 Ending Explained (Full Movie Breakdown):
https://youtu.be/Irwa2CDFZ_4
DUNE PART 2 Explained: The Biggest Questions Answered:
https://youtu.be/1yaskq17yiI
DUNE PART 2 Explained: The Meaning Of Paul's Visions:
https://youtu.be/bQXWccYONBc
DUNE PART 2 - Biggest Differences Between The Movie And Book:
https://youtu.be/5d1v1Rcc_2k
DUNE PART 2 Reviews Call It A MASTERPIECE!:
https://youtu.be/IlN8YXf_xG4
DUNE PART 2 Will Change Movies Forever:
https://bit.ly/3J4Su10
DUNE PART 2 - Creating The Ending Scene:
https://youtu.be/OsIGk50-J7Y
DUNE PART 2 - Why Feyd Rautha Can Be A Great Villain:
https://youtu.be/ZgxFvYGJYWU
DUNE PART 2 First 10 Minutes Breakdown (New Footage Description & Details):
https://youtu.be/PrqslqRK6Y4
DUNE PART 2 Trailer Breakdown & Review - The Best Trailer Yet:
https://youtu.be/6WvBqRQ7_iU
DUNE PART 2 Trailer Breakdown & Review - This Looks Like A Masterpiece:
https://bit.ly/3prTgQU
DUNE: The Denis Villeneuve Trilogy:
https://bit.ly/3N7GTmM
Why DUNE Is A Modern Masterpiece:
https://bit.ly/3nyniiu
DUNE Review - The Best Movie Of The Year:
https://bit.ly/3HwpeQF
DUNE Explained: The Biggest Questions Answered:
https://bit.ly/3x33OWk
DUNE Ending Explained (Full Movie Breakdown):
https://bit.ly/3DAMOZY
DUNE PART 2 | Destiny Arrives:
https://youtu.be/fanoWA9o6k0
DUNE: Part Two - Official Trailer:
https://bit.ly/3ASgTo8
DUNE: Part Two - Official Trailer 2:
https://youtu.be/_YUzQa_1RCE
DUNE: Part Two - Official Trailer 3:
https://youtu.be/U2Qp5pL3ovA?si=GFnn1l9Xv4g_HpLh
Timestamps:
0:00 Intro
1:33 Denis Villeneuve On Changing The Dune Part 2 Ending
7:11 How The Dune Part 2 Ending Could Connect To Dune Messiah
Follow Cortex on Social Media:
https://twitter.com/CortexVideos
https://www.facebook.com/CortexVideos
https://www.reddit.com/r/CortexVideos
https://www.instagram.com/CortexVideos
DUNE PART 2 - Denis Villeneuve On The Ending Change
- published: 15 Jun 2024
- views: 6101
4:15
skibidi toilet 73 (part 2)
titans confront g-toilet
full-screen version
Respectful assets used in the video:
suits - https://steamcommunity.com/sharedfiles/filedetails/?id=2849230339
sp...
titans confront g-toilet
full-screen version
Respectful assets used in the video:
suits - https://steamcommunity.com/sharedfiles/filedetails/?id=2849230339
speakers models by ivip -https://steamcommunity.com/sharedfiles/filedetails/?id=2680336465
https://steamcommunity.com/sharedfiles/filedetails/?id=2684729253
map - https://steamcommunity.com/sharedfiles/filedetails/?id=1958007290
additional particles by @HoovyTube
Contact me:
instagram.com/dafuqboomtv
blugrayguy@gmail.com
https://wn.com/Skibidi_Toilet_73_(Part_2)
titans confront g-toilet
full-screen version
Respectful assets used in the video:
suits - https://steamcommunity.com/sharedfiles/filedetails/?id=2849230339
speakers models by ivip -https://steamcommunity.com/sharedfiles/filedetails/?id=2680336465
https://steamcommunity.com/sharedfiles/filedetails/?id=2684729253
map - https://steamcommunity.com/sharedfiles/filedetails/?id=1958007290
additional particles by @HoovyTube
Contact me:
instagram.com/dafuqboomtv
blugrayguy@gmail.com
- published: 03 May 2024
- views: 37890911
20:36
PART 2 | IDOL RAFFY, NALUHA SA KASO NG MOVE IT RIDER NA NAPAGBINTANGANG HOLDAPER!
PART 1: https://youtu.be/e_9fxd0NsZQ
⚠️PARA SA INYONG MGA SUMBONG AT REKLAMO ⚠️
Maaari po kayong magtungo sa ACTION CENTER ng RAFFY TULFO IN ACTION sa TV5 Med...
PART 1: https://youtu.be/e_9fxd0NsZQ
⚠️PARA SA INYONG MGA SUMBONG AT REKLAMO ⚠️
Maaari po kayong magtungo sa ACTION CENTER ng RAFFY TULFO IN ACTION sa TV5 Media Center, Reliance Cor. Sheridan St., Mandaluyong mul a 9:00AM-3:00PM, tuwing Lunes hanggang Biyernes. Mangyari lamang po na magdala ng vaccination card at huwag nang magsama ng bata. Kung kayo naman ay senior citizen o may karamdaman, magpadala na lamang po kayo ng inyong representative sa aming tanggapan. Gaya po ng aming paalala, LIBRE at WALA PONG BAYAD ang serbisyong aming ibinibigay kaya 'wag na 'wag po kayong magpapaloko sa mga scammers na mangangako na pauunahin kayo sa pila at maniningil ng bayad.
#RTIA #TULFO #IDOLRAFFY #SENATORRAFFY #WANTEDSARADYO
#SUMBONGATAKSYON #RAFFYTULFO #RAFFY #TULFO #RAFFYTULFOINACTION #WSR #TULFOLIVE
https://wn.com/Part_2_|_Idol_Raffy,_Naluha_Sa_Kaso_Ng_Move_It_Rider_Na_Napagbintangang_Holdaper
PART 1: https://youtu.be/e_9fxd0NsZQ
⚠️PARA SA INYONG MGA SUMBONG AT REKLAMO ⚠️
Maaari po kayong magtungo sa ACTION CENTER ng RAFFY TULFO IN ACTION sa TV5 Media Center, Reliance Cor. Sheridan St., Mandaluyong mul a 9:00AM-3:00PM, tuwing Lunes hanggang Biyernes. Mangyari lamang po na magdala ng vaccination card at huwag nang magsama ng bata. Kung kayo naman ay senior citizen o may karamdaman, magpadala na lamang po kayo ng inyong representative sa aming tanggapan. Gaya po ng aming paalala, LIBRE at WALA PONG BAYAD ang serbisyong aming ibinibigay kaya 'wag na 'wag po kayong magpapaloko sa mga scammers na mangangako na pauunahin kayo sa pila at maniningil ng bayad.
#RTIA #TULFO #IDOLRAFFY #SENATORRAFFY #WANTEDSARADYO
#SUMBONGATAKSYON #RAFFYTULFO #RAFFY #TULFO #RAFFYTULFOINACTION #WSR #TULFOLIVE
- published: 06 Jun 2024
- views: 2824895
2:43
Rebel Moon — Part Two: The Scargiver | Official Trailer | Netflix
REBEL MOON — PART TWO: THE SCARGIVER premieres on Netflix April 19, 2024.
REBEL MOON — PART TWO: THE SCARGIVER continues the epic saga of Kora and the survivin...
REBEL MOON — PART TWO: THE SCARGIVER premieres on Netflix April 19, 2024.
REBEL MOON — PART TWO: THE SCARGIVER continues the epic saga of Kora and the surviving warriors as they prepare to sacrifice everything, fighting alongside the brave people of Veldt, to defend a once peaceful village, a newfound homeland for those who have lost their own in the fight against the Motherworld. On the eve of their battle the warriors must face the truths of their own pasts, each revealing why they fight. As the full force of the Realm bears down on the burgeoning rebellion, unbreakable bonds are forged, heroes emerge, and legends are made.
From Zack Snyder, the filmmaker behind 300, Man of Steel, and Army of the Dead, REBEL MOON is a 2-part movie event decades in the making.
REBEL MOON — PART ONE: A CHILD OF FIRE is now playing on Netflix.
REBEL MOON — PART TWO: THE SCARGIVER premieres on Netflix April 19, 2024.
Watch on Netflix: https://www.netflix.com/title/81624666
About Netflix:
Netflix is one of the world's leading entertainment services with over 260 million paid memberships in over 190 countries enjoying TV series, films and games across a wide variety of genres and languages. Members can play, pause and resume watching as much as they want, anytime, anywhere, and can change their plans at any time.
Rebel Moon — Part Two: The Scargiver | Official Trailer | Netflix
https://www.youtube.com/@Netflix
The rebels gear up for battle against the ruthless forces of the Motherworld as unbreakable bonds are forged, heroes emerge — and legends are made.
https://wn.com/Rebel_Moon_—_Part_Two_The_Scargiver_|_Official_Trailer_|_Netflix
REBEL MOON — PART TWO: THE SCARGIVER premieres on Netflix April 19, 2024.
REBEL MOON — PART TWO: THE SCARGIVER continues the epic saga of Kora and the surviving warriors as they prepare to sacrifice everything, fighting alongside the brave people of Veldt, to defend a once peaceful village, a newfound homeland for those who have lost their own in the fight against the Motherworld. On the eve of their battle the warriors must face the truths of their own pasts, each revealing why they fight. As the full force of the Realm bears down on the burgeoning rebellion, unbreakable bonds are forged, heroes emerge, and legends are made.
From Zack Snyder, the filmmaker behind 300, Man of Steel, and Army of the Dead, REBEL MOON is a 2-part movie event decades in the making.
REBEL MOON — PART ONE: A CHILD OF FIRE is now playing on Netflix.
REBEL MOON — PART TWO: THE SCARGIVER premieres on Netflix April 19, 2024.
Watch on Netflix: https://www.netflix.com/title/81624666
About Netflix:
Netflix is one of the world's leading entertainment services with over 260 million paid memberships in over 190 countries enjoying TV series, films and games across a wide variety of genres and languages. Members can play, pause and resume watching as much as they want, anytime, anywhere, and can change their plans at any time.
Rebel Moon — Part Two: The Scargiver | Official Trailer | Netflix
https://www.youtube.com/@Netflix
The rebels gear up for battle against the ruthless forces of the Motherworld as unbreakable bonds are forged, heroes emerge — and legends are made.
- published: 18 Mar 2024
- views: 9843692
3:42
the skibidi wars 104 (part 2)
titans arrive to try and regain control of sonar titan.
special thanks to @HoovyTube for custom particles!
original concept by @DaFuqBoom
skibidi dop dop d...
titans arrive to try and regain control of sonar titan.
special thanks to @HoovyTube for custom particles!
original concept by @DaFuqBoom
skibidi dop dop dop yes yes
this is the continuation of the Skibidi Wars series.
full-screen version
skibidi wars S24 E04
Join my Official Discord Server: https://discord.gg/virlance
Become member of my channel here for access to exclusive gadgets, behind the scenes, exclusive sneak peeks and much more:
https://www.youtube.com/channel/UCtMW9MSme3cw-kqhKenF13A/join
This series is not the original skibidi toilet series, but a fan made version that features an alternate plot line of the skibidi toilet series. All videos are created solely by me.
https://wn.com/The_Skibidi_Wars_104_(Part_2)
titans arrive to try and regain control of sonar titan.
special thanks to @HoovyTube for custom particles!
original concept by @DaFuqBoom
skibidi dop dop dop yes yes
this is the continuation of the Skibidi Wars series.
full-screen version
skibidi wars S24 E04
Join my Official Discord Server: https://discord.gg/virlance
Become member of my channel here for access to exclusive gadgets, behind the scenes, exclusive sneak peeks and much more:
https://www.youtube.com/channel/UCtMW9MSme3cw-kqhKenF13A/join
This series is not the original skibidi toilet series, but a fan made version that features an alternate plot line of the skibidi toilet series. All videos are created solely by me.
- published: 15 Jun 2024
- views: 7101528
4:39
Man Wants His Two Mercedes Back! I Part 2
Jorge claims former business partner George sold two vehicles that belong to him for parts, but George says they’re inoperable.
The Original! There’s only ONE ...
Jorge claims former business partner George sold two vehicles that belong to him for parts, but George says they’re inoperable.
The Original! There’s only ONE Judge Judy. Visit our website for where to watch, weekdays.
Subscribe to Judge Judy on YouTube: https://www.youtube.com/channel/UCzMPPxbQG6iZttQhq3ukXSg?sub_confirmation=1
#JudgeJudy
https://wn.com/Man_Wants_His_Two_Mercedes_Back_I_Part_2
Jorge claims former business partner George sold two vehicles that belong to him for parts, but George says they’re inoperable.
The Original! There’s only ONE Judge Judy. Visit our website for where to watch, weekdays.
Subscribe to Judge Judy on YouTube: https://www.youtube.com/channel/UCzMPPxbQG6iZttQhq3ukXSg?sub_confirmation=1
#JudgeJudy
- published: 14 Jun 2024
- views: 62363
26:53
Dune Part Two FULL Breakdown, Easter Eggs and Ending Explained
Dune Part Two. Paul Atriedes Becomes A God Kwisatz Haderach Ending Explained. Paul Atriedes vs Feyd. Lore & History, Dune Messiah Dune 3 Teaser Trailer, Alia Ex...
Dune Part Two. Paul Atriedes Becomes A God Kwisatz Haderach Ending Explained. Paul Atriedes vs Feyd. Lore & History, Dune Messiah Dune 3 Teaser Trailer, Alia Explained & Kwisatz Haderach Powers ► https://bit.ly/AwesomeSubscribe
Henry Cavill Joins The Marvel Universe https://www.youtube.com/watch?v=ObnVqcD1qC0&list=PLOIeYdZ3QczwWT3yd94Xc6n-ooI85uV_u&index=1&pp=gAQBiAQB
Moon Knight Season 2 Teaser https://www.youtube.com/watch?v=HJew806Gx6c&list=PLOIeYdZ3QczxQXxyV_2D8kuEs_QsuQIyJ&index=1&pp=gAQBiAQB
Venom 3 Teaser https://www.youtube.com/watch?v=ZJDuVz4C__M&list=PLOIeYdZ3QczxQXxyV_2D8kuEs_QsuQIyJ&index=2&pp=gAQBiAQB
Deadpool and Wolverine Trailer https://www.youtube.com/watch?v=xSALmuCG0YE&list=PLOIeYdZ3QczwWT3yd94Xc6n-ooI85uV_u&index=1
Fantastic Four Teaser https://www.youtube.com/watch?v=QM2Oc0ioo9U&list=PLOIeYdZ3QczwWT3yd94Xc6n-ooI85uV_u&index=1&pp=gAQBiAQB
Godzilla X Kong Trailer https://www.youtube.com/watch?v=AQaScIxI3yY&list=PLOIeYdZ3QczxQXxyV_2D8kuEs_QsuQIyJ&index=3&pp=gAQBiAQB
Emergency Awesome New Videos https://www.youtube.com/watch?v=FeOfhzu7ZdY&list=PLOIeYdZ3QczxQXxyV_2D8kuEs_QsuQIyJ&index=7
Covering Dune Part Two Full Breakdown and Easter Eggs. Dune Part Two Ending Explained. Dune Part Three Teaser Trailer, Dune Messiah. The Empire Strikes Back comparison. DUne Part Two vs Dune Part One Movie. Paul Atreides unites with Chani and the Fremen while seeking revenge against the conspirators who destroyed his family. Facing a choice between the love of his life and the fate of the universe, he must prevent a terrible future only he can foresee. Florence Pugh Princess Irulan Explained. Emperor Shaddam IV, Austin Butler Feyd Explained. And other new characters. Kwisatz Haderach Powers Explained.
Dune Part 1 Easter Eggs and Ending Explained. What Paul Atreides Visions Mean. Dune 1984 Movie Changes and Dune Book Changes. Star Wars Movies George Lucas Inspiration. Arrakis, Sandworms, Characters and Dune Movies Mythology. Dune Books Explained and Backstory. Timothee Chalamet, Jason Momoa, Oscar Isaac, Josh Brolin, Dave Bautista, Zendaya.
Dune is a science fiction novel written by Frank Herbert and published in 1965. Set far in the future amidst a sprawling feudal interstellar empire where planetary fiefdoms are controlled by noble houses that owe allegiance to the Emperor of the Universe of Imperial House Corrino. The story tells follows Paul Atreides as he and his family relocate to the desert planet Arrakis, the only source of the spice melange
Dune Part 1 only covers half the story of the first Dune Book. The Dune Part 2 movie will cover the remainder. With possible future sequels covering the events of Children of Dune and God Emperor of Dune.
Lots more Marvel Trailers coming Avengers 5 Kang Dynasty Trailer, Avengers 6 Secret Wars Trailer, Thunderbolts Trailer, Captain America 4, Deadpool 3 Wolverine Trailer and more Fantastic Four Teaser videos!
More Deadpool and Wolverine videos and Godzilla X Kong Trailers coming soon!
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Twitter https://x.com/awesomemergency
Facebook https://facebook.com/emergencyawesome
Instagram https://instagram.com/emergencyawesome
Tumblr https://robotchallenger.com
My Website https://emergencyawesome.com
:: Video Playlists For Shows ::
New Emergency Awesome Videos https://www.youtube.com/playlist?list=PLOIeYdZ3QczxQXxyV_2D8kuEs_QsuQIyJ
House of The Dragon Episodes https://www.youtube.com/playlist?list=PLOIeYdZ3QczxqJeNeCsF_ghizcTS9nM4X
Loki Episodes https://www.youtube.com/playlist?list=PLOIeYdZ3Qczy8mUNqHU-35xtTd-JpJU3l
The Mandalorian Episodes https://www.youtube.com/playlist?list=PLOIeYdZ3QczzsN78nOjS-ABHwKaB7KONW
Game of Thrones Episodes https://www.youtube.com/playlist?list=SPOIeYdZ3QczxGuSDE8NtOuthqbKFChC0q
Marvel Movies and Avengers https://www.youtube.com/playlist?list=PLOIeYdZ3QczwWT3yd94Xc6n-ooI85uV_u
Rick and Morty Season 7 Episodes https://www.youtube.com/playlist?list=PLOIeYdZ3Qczyvx-lFYzOv9s6bOv7b9wYR
Avatar The Last Airbender Episodes https://www.youtube.com/playlist?list=PLOIeYdZ3Qczx-z2jyyX4naSnE1A8d0hkC
The Boys Season 4 Episodes https://www.youtube.com/playlist?list=PLOIeYdZ3Qczw-KMQyuCrxcxV3mSQWTAdR
Spider Man Videos https://www.youtube.com/playlist?list=PLOIeYdZ3QczzbRhRiGhj3-MaZ_24kadOy
The Batman and DC Movies https://www.youtube.com/playlist?list=PLOIeYdZ3QczwCLH9RIm-7ui56ameRYmdQ
Justice League Snyder Cut Videos https://www.youtube.com/playlist?list=PLOIeYdZ3QczwCLH9RIm-7ui56ameRYmdQ
Star Wars Movies https://www.youtube.com/playlist?list=PLOIeYdZ3QczztMg8cT1WS0P8ATv-MhUEJ
THANKS FOR WATCHING!!
https://wn.com/Dune_Part_Two_Full_Breakdown,_Easter_Eggs_And_Ending_Explained
Dune Part Two. Paul Atriedes Becomes A God Kwisatz Haderach Ending Explained. Paul Atriedes vs Feyd. Lore & History, Dune Messiah Dune 3 Teaser Trailer, Alia Explained & Kwisatz Haderach Powers ► https://bit.ly/AwesomeSubscribe
Henry Cavill Joins The Marvel Universe https://www.youtube.com/watch?v=ObnVqcD1qC0&list=PLOIeYdZ3QczwWT3yd94Xc6n-ooI85uV_u&index=1&pp=gAQBiAQB
Moon Knight Season 2 Teaser https://www.youtube.com/watch?v=HJew806Gx6c&list=PLOIeYdZ3QczxQXxyV_2D8kuEs_QsuQIyJ&index=1&pp=gAQBiAQB
Venom 3 Teaser https://www.youtube.com/watch?v=ZJDuVz4C__M&list=PLOIeYdZ3QczxQXxyV_2D8kuEs_QsuQIyJ&index=2&pp=gAQBiAQB
Deadpool and Wolverine Trailer https://www.youtube.com/watch?v=xSALmuCG0YE&list=PLOIeYdZ3QczwWT3yd94Xc6n-ooI85uV_u&index=1
Fantastic Four Teaser https://www.youtube.com/watch?v=QM2Oc0ioo9U&list=PLOIeYdZ3QczwWT3yd94Xc6n-ooI85uV_u&index=1&pp=gAQBiAQB
Godzilla X Kong Trailer https://www.youtube.com/watch?v=AQaScIxI3yY&list=PLOIeYdZ3QczxQXxyV_2D8kuEs_QsuQIyJ&index=3&pp=gAQBiAQB
Emergency Awesome New Videos https://www.youtube.com/watch?v=FeOfhzu7ZdY&list=PLOIeYdZ3QczxQXxyV_2D8kuEs_QsuQIyJ&index=7
Covering Dune Part Two Full Breakdown and Easter Eggs. Dune Part Two Ending Explained. Dune Part Three Teaser Trailer, Dune Messiah. The Empire Strikes Back comparison. DUne Part Two vs Dune Part One Movie. Paul Atreides unites with Chani and the Fremen while seeking revenge against the conspirators who destroyed his family. Facing a choice between the love of his life and the fate of the universe, he must prevent a terrible future only he can foresee. Florence Pugh Princess Irulan Explained. Emperor Shaddam IV, Austin Butler Feyd Explained. And other new characters. Kwisatz Haderach Powers Explained.
Dune Part 1 Easter Eggs and Ending Explained. What Paul Atreides Visions Mean. Dune 1984 Movie Changes and Dune Book Changes. Star Wars Movies George Lucas Inspiration. Arrakis, Sandworms, Characters and Dune Movies Mythology. Dune Books Explained and Backstory. Timothee Chalamet, Jason Momoa, Oscar Isaac, Josh Brolin, Dave Bautista, Zendaya.
Dune is a science fiction novel written by Frank Herbert and published in 1965. Set far in the future amidst a sprawling feudal interstellar empire where planetary fiefdoms are controlled by noble houses that owe allegiance to the Emperor of the Universe of Imperial House Corrino. The story tells follows Paul Atreides as he and his family relocate to the desert planet Arrakis, the only source of the spice melange
Dune Part 1 only covers half the story of the first Dune Book. The Dune Part 2 movie will cover the remainder. With possible future sequels covering the events of Children of Dune and God Emperor of Dune.
Lots more Marvel Trailers coming Avengers 5 Kang Dynasty Trailer, Avengers 6 Secret Wars Trailer, Thunderbolts Trailer, Captain America 4, Deadpool 3 Wolverine Trailer and more Fantastic Four Teaser videos!
More Deadpool and Wolverine videos and Godzilla X Kong Trailers coming soon!
Twitch Channel https://twitch.tv/emergencyawesome
Twitter https://x.com/awesomemergency
Facebook https://facebook.com/emergencyawesome
Instagram https://instagram.com/emergencyawesome
Tumblr https://robotchallenger.com
My Website https://emergencyawesome.com
:: Video Playlists For Shows ::
New Emergency Awesome Videos https://www.youtube.com/playlist?list=PLOIeYdZ3QczxQXxyV_2D8kuEs_QsuQIyJ
House of The Dragon Episodes https://www.youtube.com/playlist?list=PLOIeYdZ3QczxqJeNeCsF_ghizcTS9nM4X
Loki Episodes https://www.youtube.com/playlist?list=PLOIeYdZ3Qczy8mUNqHU-35xtTd-JpJU3l
The Mandalorian Episodes https://www.youtube.com/playlist?list=PLOIeYdZ3QczzsN78nOjS-ABHwKaB7KONW
Game of Thrones Episodes https://www.youtube.com/playlist?list=SPOIeYdZ3QczxGuSDE8NtOuthqbKFChC0q
Marvel Movies and Avengers https://www.youtube.com/playlist?list=PLOIeYdZ3QczwWT3yd94Xc6n-ooI85uV_u
Rick and Morty Season 7 Episodes https://www.youtube.com/playlist?list=PLOIeYdZ3Qczyvx-lFYzOv9s6bOv7b9wYR
Avatar The Last Airbender Episodes https://www.youtube.com/playlist?list=PLOIeYdZ3Qczx-z2jyyX4naSnE1A8d0hkC
The Boys Season 4 Episodes https://www.youtube.com/playlist?list=PLOIeYdZ3Qczw-KMQyuCrxcxV3mSQWTAdR
Spider Man Videos https://www.youtube.com/playlist?list=PLOIeYdZ3QczzbRhRiGhj3-MaZ_24kadOy
The Batman and DC Movies https://www.youtube.com/playlist?list=PLOIeYdZ3QczwCLH9RIm-7ui56ameRYmdQ
Justice League Snyder Cut Videos https://www.youtube.com/playlist?list=PLOIeYdZ3QczwCLH9RIm-7ui56ameRYmdQ
Star Wars Movies https://www.youtube.com/playlist?list=PLOIeYdZ3QczztMg8cT1WS0P8ATv-MhUEJ
THANKS FOR WATCHING!!
- published: 02 Mar 2024
- views: 974016
-
CTG Basics
Let's start off with the basics of CTGs. From how a CTG trace is drawn up to CTG interpretation with Dr C Bravado.
Like and Subscribe!
published: 06 Dec 2021
-
CTG Basics Part 2 - Decelerations & Fetal Physiology
Continuing our discussion on CTGs with the basics of fetal physiology and decelerations.
Watch my first video CTG Basics:
https://youtu.be/I5Dj9vKhlMQ
Like and Subscribe!
published: 28 Feb 2022
-
CTG INTERPRETATION
Basics of CTG, you will never miss this OSCE station now-onwards
published: 01 Oct 2021
-
Testing of CTG Machine ✅ Fetal Monitoring 🐣Biomed dude #ctg #fetalmonitor #biomedical #selftest
published: 02 Jun 2023
-
Cardiotocography (Fetal Monitors) | Part 1| Introduction | Biomedical Engineers TV
Video Content
Introduction to Fetal Monitor
Working Principle of CTG
Types Of CTG
Video & Text Credits mentioned at last
published: 25 Aug 2020
-
CTG Basics Part 3 - Overall Assessment & Examples
The final video from my CTG series!
Learn about the Overall Assessment of the CTG and understand better with some examples.
Watch the first 2 videos of the CTG series here:
https://youtu.be/I5Dj9vKhlMQ
https://youtu.be/-GgRTexXbic
Like and Subscribe!
published: 15 Mar 2022
-
SEXTA - FEIRA - CTG JÚLIO DE CASTILHOS | JÚLIO DE CASTILHOS - RS
(55)9 9600 0099
TRANSMISSÃO AO VIVO
CANAL ORELHANO - RS
published: 31 Jan 2025
-
CTG Made Easy. For Begginers.
🏥 The Medicable Forum 🏥 - Your Ultimate Medical Concepts Hub!
🔍 Unraveling the Mystery of CTG: Understanding the Basics 📚
Welcome to The Medicable Forum, your go-to destination for comprehensive medical knowledge! In this video, we delve deep into the intricacies of reading a CTG (Cardiotocography) with crystal-clear explanations. Whether you're preparing for international medical exams like USMLE, PLAB, or AMC, or simply seeking to expand your medical expertise, this video is tailored just for you!
📹 Join our community and subscribe for more valuable updates on medicine and exam tips! Don't forget to hit that notification bell, so you never miss a life-changing insight.
In this enlightening video, we cover:
📌 The fundamentals of Cardiotocography (CTG) - what it is and why it's essent...
published: 05 Jul 2019
-
Fetal Monitoring in Labor, NICE Guideline (2022) / Updates in Cardiotocography, CTG
Fetal monitoring in Labor is well explained in the latest NICE guideline about intrapartum Care published in December 2022. This guideline covers methods for monitoring the wellbeing of the baby during labor. It includes risk assessment to determine the appropriate level of fetal monitoring, using clinical assessment in addition to fetal monitoring, and interpreting and acting on monitoring findings.
Intermittent auscultation is a safe and acceptable fetal monitoring method that is recommended during labor with low-risk pregnancies. There are two methods for fetal heart rate monitoring, external and internal. External fetal heart rate monitoring uses a device to listen to or record the fetal heartbeat through the mother's abdomen. Internal fetal heart rate monitoring uses an electronic tra...
published: 27 Jul 2023
-
CPPP CTG - O que é o CTG? pela Enf.ª Daniela Marques
Sabe o que é o CTG ou Cardiotocografia? E qual a sua importância?
A formadora do curso Daniela Marques explica o que é este exame e para que serve. Conheça mais sobre o curso em cintramedica.pt
published: 12 Jun 2024
6:22
CTG Basics
Let's start off with the basics of CTGs. From how a CTG trace is drawn up to CTG interpretation with Dr C Bravado.
Like and Subscribe!
Let's start off with the basics of CTGs. From how a CTG trace is drawn up to CTG interpretation with Dr C Bravado.
Like and Subscribe!
https://wn.com/Ctg_Basics
Let's start off with the basics of CTGs. From how a CTG trace is drawn up to CTG interpretation with Dr C Bravado.
Like and Subscribe!
- published: 06 Dec 2021
- views: 389423
8:26
CTG Basics Part 2 - Decelerations & Fetal Physiology
Continuing our discussion on CTGs with the basics of fetal physiology and decelerations.
Watch my first video CTG Basics:
https://youtu.be/I5Dj9vKhlMQ
Like an...
Continuing our discussion on CTGs with the basics of fetal physiology and decelerations.
Watch my first video CTG Basics:
https://youtu.be/I5Dj9vKhlMQ
Like and Subscribe!
https://wn.com/Ctg_Basics_Part_2_Decelerations_Fetal_Physiology
Continuing our discussion on CTGs with the basics of fetal physiology and decelerations.
Watch my first video CTG Basics:
https://youtu.be/I5Dj9vKhlMQ
Like and Subscribe!
- published: 28 Feb 2022
- views: 196932
11:36
CTG INTERPRETATION
Basics of CTG, you will never miss this OSCE station now-onwards
Basics of CTG, you will never miss this OSCE station now-onwards
https://wn.com/Ctg_Interpretation
Basics of CTG, you will never miss this OSCE station now-onwards
- published: 01 Oct 2021
- views: 81555
6:27
Cardiotocography (Fetal Monitors) | Part 1| Introduction | Biomedical Engineers TV
Video Content
Introduction to Fetal Monitor
Working Principle of CTG
Types Of CTG
Video & Text Credits mentioned at last
Video Content
Introduction to Fetal Monitor
Working Principle of CTG
Types Of CTG
Video & Text Credits mentioned at last
https://wn.com/Cardiotocography_(Fetal_Monitors)_|_Part_1|_Introduction_|_Biomedical_Engineers_Tv
Video Content
Introduction to Fetal Monitor
Working Principle of CTG
Types Of CTG
Video & Text Credits mentioned at last
- published: 25 Aug 2020
- views: 71237
12:30
CTG Basics Part 3 - Overall Assessment & Examples
The final video from my CTG series!
Learn about the Overall Assessment of the CTG and understand better with some examples.
Watch the first 2 videos of the CTG...
The final video from my CTG series!
Learn about the Overall Assessment of the CTG and understand better with some examples.
Watch the first 2 videos of the CTG series here:
https://youtu.be/I5Dj9vKhlMQ
https://youtu.be/-GgRTexXbic
Like and Subscribe!
https://wn.com/Ctg_Basics_Part_3_Overall_Assessment_Examples
The final video from my CTG series!
Learn about the Overall Assessment of the CTG and understand better with some examples.
Watch the first 2 videos of the CTG series here:
https://youtu.be/I5Dj9vKhlMQ
https://youtu.be/-GgRTexXbic
Like and Subscribe!
- published: 15 Mar 2022
- views: 123346
25:33
CTG Made Easy. For Begginers.
🏥 The Medicable Forum 🏥 - Your Ultimate Medical Concepts Hub!
🔍 Unraveling the Mystery of CTG: Understanding the Basics 📚
Welcome to The Medicable Forum, your...
🏥 The Medicable Forum 🏥 - Your Ultimate Medical Concepts Hub!
🔍 Unraveling the Mystery of CTG: Understanding the Basics 📚
Welcome to The Medicable Forum, your go-to destination for comprehensive medical knowledge! In this video, we delve deep into the intricacies of reading a CTG (Cardiotocography) with crystal-clear explanations. Whether you're preparing for international medical exams like USMLE, PLAB, or AMC, or simply seeking to expand your medical expertise, this video is tailored just for you!
📹 Join our community and subscribe for more valuable updates on medicine and exam tips! Don't forget to hit that notification bell, so you never miss a life-changing insight.
In this enlightening video, we cover:
📌 The fundamentals of Cardiotocography (CTG) - what it is and why it's essential in obstetric care.
📌 Interpreting fetal heart rate patterns and understanding their significance.
📌 The uterine contraction patterns and their impact on fetal well-being.
📌 Identifying various CTG traces and their corresponding clinical implications.
📌 Recognizing normal vs. abnormal CTG patterns and knowing when to take immediate action.
📌 Clinical case studies to reinforce your understanding and boost your confidence.
👨⚕️ As a bonus, gain exclusive insights into the life of a specialty trainee on my personal blog. Discover the challenges, the highs, and the rewards of being in the medical field, all shared from my own experiences.
Whether you're a medical student, a resident, or a seasoned healthcare professional, this video equips you with the essential skills to master CTG reading. Enhance your medical prowess, ace those exams, and make a real difference in the lives of expectant mothers and their babies.
🎥 Watch now and empower yourself with the knowledge that saves lives. Remember to like the video and share it with your fellow medical enthusiasts.
🌐 Follow The Medicable Forum for more exciting updates, and let's journey together towards medical excellence!
#TheMedicableForum #CTGExplained #MedicalConcepts #USMLE #PLAB #AMC #Medicine #SpecialtyTrainee #Obstetrics #Gynecology #MedicalEducation #StudyWithMe #MedicalExams #SubscribeNow
https://wn.com/Ctg_Made_Easy._For_Begginers.
🏥 The Medicable Forum 🏥 - Your Ultimate Medical Concepts Hub!
🔍 Unraveling the Mystery of CTG: Understanding the Basics 📚
Welcome to The Medicable Forum, your go-to destination for comprehensive medical knowledge! In this video, we delve deep into the intricacies of reading a CTG (Cardiotocography) with crystal-clear explanations. Whether you're preparing for international medical exams like USMLE, PLAB, or AMC, or simply seeking to expand your medical expertise, this video is tailored just for you!
📹 Join our community and subscribe for more valuable updates on medicine and exam tips! Don't forget to hit that notification bell, so you never miss a life-changing insight.
In this enlightening video, we cover:
📌 The fundamentals of Cardiotocography (CTG) - what it is and why it's essential in obstetric care.
📌 Interpreting fetal heart rate patterns and understanding their significance.
📌 The uterine contraction patterns and their impact on fetal well-being.
📌 Identifying various CTG traces and their corresponding clinical implications.
📌 Recognizing normal vs. abnormal CTG patterns and knowing when to take immediate action.
📌 Clinical case studies to reinforce your understanding and boost your confidence.
👨⚕️ As a bonus, gain exclusive insights into the life of a specialty trainee on my personal blog. Discover the challenges, the highs, and the rewards of being in the medical field, all shared from my own experiences.
Whether you're a medical student, a resident, or a seasoned healthcare professional, this video equips you with the essential skills to master CTG reading. Enhance your medical prowess, ace those exams, and make a real difference in the lives of expectant mothers and their babies.
🎥 Watch now and empower yourself with the knowledge that saves lives. Remember to like the video and share it with your fellow medical enthusiasts.
🌐 Follow The Medicable Forum for more exciting updates, and let's journey together towards medical excellence!
#TheMedicableForum #CTGExplained #MedicalConcepts #USMLE #PLAB #AMC #Medicine #SpecialtyTrainee #Obstetrics #Gynecology #MedicalEducation #StudyWithMe #MedicalExams #SubscribeNow
- published: 05 Jul 2019
- views: 69536
20:04
Fetal Monitoring in Labor, NICE Guideline (2022) / Updates in Cardiotocography, CTG
Fetal monitoring in Labor is well explained in the latest NICE guideline about intrapartum Care published in December 2022. This guideline covers methods for mo...
Fetal monitoring in Labor is well explained in the latest NICE guideline about intrapartum Care published in December 2022. This guideline covers methods for monitoring the wellbeing of the baby during labor. It includes risk assessment to determine the appropriate level of fetal monitoring, using clinical assessment in addition to fetal monitoring, and interpreting and acting on monitoring findings.
Intermittent auscultation is a safe and acceptable fetal monitoring method that is recommended during labor with low-risk pregnancies. There are two methods for fetal heart rate monitoring, external and internal. External fetal heart rate monitoring uses a device to listen to or record the fetal heartbeat through the mother's abdomen. Internal fetal heart rate monitoring uses an electronic transducer connected directly to the fetal skin.
#fetalmonitoring
#fetalmonitoringduringlabor
#fetalmonitoringmachine
#latedecelerationsonfetalmonitoring
#continuousfetalmonitoring
#fetalhearttonemonitoring
#electronicfetalmonitoring
#whatisfetalmonitoring
#whatisfetalmonitoringinlabor
------------------------------------------------------------------
This Channel is providing knowledge in the field of Obstetrics and Gynaecology. Obstetrics is related to medical and surgical care before, during, and after a woman gives birth. Obstetrics focuses on caring for and maintaining a woman’s overall health during maternity. This includes pregnancy, labor, childbirth, and the postpartum period. Gynaecology on the other hand focuses on women’s bodies and their reproductive health. It includes the diagnosis, treatment, and care of women’s reproductive system. This includes vagina, uterus, ovaries, and fallopian tubes. Gynaecology also includes screening for and treating issues associated with women’s breasts. Gynaecology is the overarching field of women’s health from puberty through adulthood. It represents most of the reproductive care you’ll receive during your lifetime. If you become pregnant, you’ll need to go to an obstetrician.
The channel will have videos on the topics of Obstetrics and Gynaecology which will include but not limited to:
abnormal bleeding
pelvic pain
genital itching
urinary incontinence
urinary tract or vaginal infections
endometriosis
breast disorders
hormonal disorders
dilation and curettage
biopsy
tubal ligation for female sterilization
laser surgery
hysterectomy, or the removal of the uterus
myomectomy, or the removal of fibroids
in vitro fertilization
vaginal delivery
caesarean delivery
amniocentesis to determine sex and detect any abnormalities
forceps and vacuum deliveries
pelvic exams
pap smears
clinical breast exams
mammographies
cancer screenings
perimenopause
menopause
birth control, contraception, or sterilization
advice on preventing or treating sexually transmitted infections or HIV
vaccination against the human papilloma virus
treatment and prevention of pain during sex
abnormal vaginal discharge
urinary tract infections
prenatal care
infertility treatment
advice on diet
labor and birthing options
genetic testing and screenings
advice on breast-feeding
postpartum depression
easing cramps
irregular or abnormal bleeding
mood swings
advice about premenstrual syndrome
cysts and fibroids
pelvic support problems
a low libido
vaginal dryness
hot flushes
bone loss
incontinence
hormone replacement therapy
https://wn.com/Fetal_Monitoring_In_Labor,_Nice_Guideline_(2022)_Updates_In_Cardiotocography,_Ctg
Fetal monitoring in Labor is well explained in the latest NICE guideline about intrapartum Care published in December 2022. This guideline covers methods for monitoring the wellbeing of the baby during labor. It includes risk assessment to determine the appropriate level of fetal monitoring, using clinical assessment in addition to fetal monitoring, and interpreting and acting on monitoring findings.
Intermittent auscultation is a safe and acceptable fetal monitoring method that is recommended during labor with low-risk pregnancies. There are two methods for fetal heart rate monitoring, external and internal. External fetal heart rate monitoring uses a device to listen to or record the fetal heartbeat through the mother's abdomen. Internal fetal heart rate monitoring uses an electronic transducer connected directly to the fetal skin.
#fetalmonitoring
#fetalmonitoringduringlabor
#fetalmonitoringmachine
#latedecelerationsonfetalmonitoring
#continuousfetalmonitoring
#fetalhearttonemonitoring
#electronicfetalmonitoring
#whatisfetalmonitoring
#whatisfetalmonitoringinlabor
------------------------------------------------------------------
This Channel is providing knowledge in the field of Obstetrics and Gynaecology. Obstetrics is related to medical and surgical care before, during, and after a woman gives birth. Obstetrics focuses on caring for and maintaining a woman’s overall health during maternity. This includes pregnancy, labor, childbirth, and the postpartum period. Gynaecology on the other hand focuses on women’s bodies and their reproductive health. It includes the diagnosis, treatment, and care of women’s reproductive system. This includes vagina, uterus, ovaries, and fallopian tubes. Gynaecology also includes screening for and treating issues associated with women’s breasts. Gynaecology is the overarching field of women’s health from puberty through adulthood. It represents most of the reproductive care you’ll receive during your lifetime. If you become pregnant, you’ll need to go to an obstetrician.
The channel will have videos on the topics of Obstetrics and Gynaecology which will include but not limited to:
abnormal bleeding
pelvic pain
genital itching
urinary incontinence
urinary tract or vaginal infections
endometriosis
breast disorders
hormonal disorders
dilation and curettage
biopsy
tubal ligation for female sterilization
laser surgery
hysterectomy, or the removal of the uterus
myomectomy, or the removal of fibroids
in vitro fertilization
vaginal delivery
caesarean delivery
amniocentesis to determine sex and detect any abnormalities
forceps and vacuum deliveries
pelvic exams
pap smears
clinical breast exams
mammographies
cancer screenings
perimenopause
menopause
birth control, contraception, or sterilization
advice on preventing or treating sexually transmitted infections or HIV
vaccination against the human papilloma virus
treatment and prevention of pain during sex
abnormal vaginal discharge
urinary tract infections
prenatal care
infertility treatment
advice on diet
labor and birthing options
genetic testing and screenings
advice on breast-feeding
postpartum depression
easing cramps
irregular or abnormal bleeding
mood swings
advice about premenstrual syndrome
cysts and fibroids
pelvic support problems
a low libido
vaginal dryness
hot flushes
bone loss
incontinence
hormone replacement therapy
- published: 27 Jul 2023
- views: 5740
0:44
CPPP CTG - O que é o CTG? pela Enf.ª Daniela Marques
Sabe o que é o CTG ou Cardiotocografia? E qual a sua importância?
A formadora do curso Daniela Marques explica o que é este exame e para que serve. Conheça ma...
Sabe o que é o CTG ou Cardiotocografia? E qual a sua importância?
A formadora do curso Daniela Marques explica o que é este exame e para que serve. Conheça mais sobre o curso em cintramedica.pt
https://wn.com/Cppp_Ctg_O_Que_É_O_Ctg_Pela_Enf.ª_Daniela_Marques
Sabe o que é o CTG ou Cardiotocografia? E qual a sua importância?
A formadora do curso Daniela Marques explica o que é este exame e para que serve. Conheça mais sobre o curso em cintramedica.pt
- published: 12 Jun 2024
- views: 204
-
Medical vocabulary: What does Nuclear Receptor Coactivator 3 mean
What does Nuclear Receptor Coactivator 3 mean in English?
published: 20 Jan 2016
-
Nuclear Receptors & Signaling Pathway
📝Find notes here: https://www.nonstopneuron.com/post/nuclear-receptors-and-their-signaling-pathway
Explore our entire animation video library at: https://www.nonstopneuron.com/
Video Summary:
Nuclear receptors are located inside the cell. They bind with a lipophilic ligand molecule. They are transcription factors. They have a ligand-binding domain, DNA binding domain, and transactivation domain. Under resting state, glucocorticoid receptors are located in the cytoplasm and are bound with chaperone protein HSP-90 that prevents its activity. Binding of glucocorticoid causes release of chaperone protein, dimerization, entry into the nucleus, binding with coregulator, binding with DNA, and modulation of transcriptional activity. Because of the involvement of protein synthesis, their effects a...
published: 28 Jul 2021
-
Intracellular Receptor Signaling || Type I and Type II Nuclear Receptor Signaling and Structure
8 Minute video on Intracellular Receptor Signaling, Structure of Nuclear receptor, Type I and Type II Nuclear receptor signaling
Check your Understanding: Diagram quiz on cell signaling: shorturl.at/afhsD
Notes on Nuclear receptors: https://www.biologyexams4u.com/2023/01/nuclear-receptors-type-i-and-type-ii.html
▶Enroll now. Our free certificate course on Introduction to Recombinant DNA Technology
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Please consider subscribing using the link: https://bit.ly/3kG2kKf
00:00| Introduction
00:20| What are Intracellular receptors?
00:42| What is Type I receptor? with example
01:16| What is Type II receptor? with example
01:45| 48 Human Nuclear receptors tree
01:5...
published: 16 Oct 2022
-
Gene Music using Protein Sequence of NCOA3 "NUCLEAR RECEPTOR COACTIVATOR 3"
Shop NCOA3 - https://www.redbubble.com/people/genemusic/works/56154066-ncoa3?asc=u
Subscribe - https://www.youtube.com/c/GeneMusicStudio?sub_confirmation=1
Gene Music Studio - A channel to taste (visually & musically) gene information (particularly protein sequences)
Gene Music using Protein Sequence of NCOA3 'NUCLEAR RECEPTOR COACTIVATOR 3'
published: 09 Nov 2017
-
Medical vocabulary: What does Nuclear Receptor Coactivators mean
What does Nuclear Receptor Coactivators mean in English?
published: 20 Jan 2016
-
Nuclear Receptors and Lipid Binding Proteins
Scientific Research Symposium - Department of Pharmacology (Part 3), Noa Noy, Ph.D. Recorded on 5-11-2007.
published: 17 Mar 2008
-
Mod-03 Lec-23 Mechanism of transcriptional activation by nuclear receptors
Eukaryotic Gene Expression:Basics & Benefits by Prof.P N RANGARAJAN,Department of Biochemistry,IISC Bangalore. For more details on NPTEL visit http://nptel.iitm.ac.in
published: 27 Sep 2011
-
Medical vocabulary: What does Nuclear Receptor Coactivator 2 mean
What does Nuclear Receptor Coactivator 2 mean in English?
published: 20 Jan 2016
-
Medical vocabulary: What does Nuclear Receptor Coactivator 1 mean
What does Nuclear Receptor Coactivator 1 mean in English?
published: 20 Jan 2016
-
Nuclear Receptor Signaling-NRS |Structure & Function|Mnemonics to Learn -Drugs Follow |Transcription
Nuclear receptors are activated by lipid-soluble signals (e.g., steroid hormones) that cross the plasma membrane. Once activated, most function as transcription factors to control gene expression for numerous biological processes.
Nuclear receptors are a family of ligand-regulated transcription factors that are activated by steroid hormones, such as estrogen and progesterone, and various other lipid-soluble signals, including retinoic acid, oxysterols, and thyroid hormone . Unlike most intercellular messengers, the ligands can cross the plasma membrane and directly interact with nuclear receptors inside the cell , rather than having to act via cell surface receptors. Once activated, nuclear receptors directly regulate transcription of genes that control a wide variety of biological proces...
published: 26 Mar 2020
-
ROR gamma coactivator and corepressor binding mode.
published: 28 Dec 2017
-
Receptors Regulating Gene Expression or Nuclear Receptors (Pharmacodynamics Part 13) | Dr. Shikha
Receptors Regulating Gene Expression or Nuclear Receptors (Pharmacodynamics Part 13) by Dr. Shikha Parmar
Nuclear Receptors
Nuclear receptors (also known as nuclear hormone receptors) are a large family of transcription factors that bind directly to DNA to regulate the expression of target genes. They regulate the cellular response to hormones such as sex steroids, vitamin D3, adrenal steroids and other metabolic ligands, and are involved in metabolism, development and reproduction.
The nuclear receptor superfamily is classified by sequence alignment and phylogenetic tree construction into six main subfamilies:
Thyroid Hormone Receptor-like: includes thyroid receptor, retinoic acid receptor, PPAR, LXR, FXR, VDR, PXR and CAR
Retinoid X Receptor-like: includes RXR
Estrogen Receptor-like ...
published: 11 Apr 2022
-
Nuclear Receptor |Transcription Factor |Intercellular Receptor | Receptor Regulating Gene Expression
Nuclear receptors are a class of transcription factors that play a crucial role in regulating gene expression in eukaryotic cells. They are a diverse family of proteins found in the cell nucleus, and their primary function is to sense and respond to various signaling molecules, including hormones, vitamins, and other small molecules.
Structure of Nuclear Receptors:
Nuclear receptors are modular proteins with a characteristic domain structure. The typical structure of a nuclear receptor consists of several domains, including:
N-terminal domain (NTD): The N-terminal domain is variable in length and sequence among different nuclear receptors. It is involved in interactions with co-regulatory proteins and can modulate the transcriptional activity of the receptor.
DNA-binding domain (DBD): Th...
published: 27 Jun 2023
-
What Is The Nuclear Receptor The Super Necklace From Pyradyne
published: 06 Jul 2017
4:47
Nuclear Receptors & Signaling Pathway
📝Find notes here: https://www.nonstopneuron.com/post/nuclear-receptors-and-their-signaling-pathway
Explore our entire animation video library at: https://www.no...
📝Find notes here: https://www.nonstopneuron.com/post/nuclear-receptors-and-their-signaling-pathway
Explore our entire animation video library at: https://www.nonstopneuron.com/
Video Summary:
Nuclear receptors are located inside the cell. They bind with a lipophilic ligand molecule. They are transcription factors. They have a ligand-binding domain, DNA binding domain, and transactivation domain. Under resting state, glucocorticoid receptors are located in the cytoplasm and are bound with chaperone protein HSP-90 that prevents its activity. Binding of glucocorticoid causes release of chaperone protein, dimerization, entry into the nucleus, binding with coregulator, binding with DNA, and modulation of transcriptional activity. Because of the involvement of protein synthesis, their effects are slow to appear and slow to disappear.
🎞 More videos on Signaling:
• G Protein Coupled Receptors: https://youtu.be/5zVysV32hVQ
• Adenylyl Cyclase - cAMP Pathway: https://youtu.be/J7LGmFgW44c
• Phospholipase C : IP3/DAG Pathway: https://youtu.be/p8JGpbxyxHE
• Receptor Tyrosine Kinase: https://youtu.be/8-cub2zRQoA
• Tyrosine Kinase-Associated Receptor: https://youtu.be/rsVZsmTf1RI
• Cell to Cell Communication: https://youtu.be/i3bY-JCYs4A
• Receptor - Types & Functions: https://youtu.be/vjFes5I07c0
• Intracellular Signaling / Second Messenger System: https://youtu.be/aIZQ3ker0KE
● Follow me at:
• Facebook: https://www.facebook.com/NonstopNeuron
• Instagram: https://www.instagram.com/NonstopNeuron/
Dr Vipul Navadiya
DISCLAIMER: This video is for education purposes only. Although every effort is made to ensure the accuracy of the material, viewers should refer to the appropriate regulatory body/authorized websites, guidelines, and other suitable sources of information as deemed relevant and applicable. In view of the possibility of human error or changes in medical science, any person or organization involved in the preparation of this work accepts no responsibility for any errors or omissions, or results obtained from the use of information in this video.
https://wn.com/Nuclear_Receptors_Signaling_Pathway
📝Find notes here: https://www.nonstopneuron.com/post/nuclear-receptors-and-their-signaling-pathway
Explore our entire animation video library at: https://www.nonstopneuron.com/
Video Summary:
Nuclear receptors are located inside the cell. They bind with a lipophilic ligand molecule. They are transcription factors. They have a ligand-binding domain, DNA binding domain, and transactivation domain. Under resting state, glucocorticoid receptors are located in the cytoplasm and are bound with chaperone protein HSP-90 that prevents its activity. Binding of glucocorticoid causes release of chaperone protein, dimerization, entry into the nucleus, binding with coregulator, binding with DNA, and modulation of transcriptional activity. Because of the involvement of protein synthesis, their effects are slow to appear and slow to disappear.
🎞 More videos on Signaling:
• G Protein Coupled Receptors: https://youtu.be/5zVysV32hVQ
• Adenylyl Cyclase - cAMP Pathway: https://youtu.be/J7LGmFgW44c
• Phospholipase C : IP3/DAG Pathway: https://youtu.be/p8JGpbxyxHE
• Receptor Tyrosine Kinase: https://youtu.be/8-cub2zRQoA
• Tyrosine Kinase-Associated Receptor: https://youtu.be/rsVZsmTf1RI
• Cell to Cell Communication: https://youtu.be/i3bY-JCYs4A
• Receptor - Types & Functions: https://youtu.be/vjFes5I07c0
• Intracellular Signaling / Second Messenger System: https://youtu.be/aIZQ3ker0KE
● Follow me at:
• Facebook: https://www.facebook.com/NonstopNeuron
• Instagram: https://www.instagram.com/NonstopNeuron/
Dr Vipul Navadiya
DISCLAIMER: This video is for education purposes only. Although every effort is made to ensure the accuracy of the material, viewers should refer to the appropriate regulatory body/authorized websites, guidelines, and other suitable sources of information as deemed relevant and applicable. In view of the possibility of human error or changes in medical science, any person or organization involved in the preparation of this work accepts no responsibility for any errors or omissions, or results obtained from the use of information in this video.
- published: 28 Jul 2021
- views: 60550
8:08
Intracellular Receptor Signaling || Type I and Type II Nuclear Receptor Signaling and Structure
8 Minute video on Intracellular Receptor Signaling, Structure of Nuclear receptor, Type I and Type II Nuclear receptor signaling
Check your Understanding: Diagr...
8 Minute video on Intracellular Receptor Signaling, Structure of Nuclear receptor, Type I and Type II Nuclear receptor signaling
Check your Understanding: Diagram quiz on cell signaling: shorturl.at/afhsD
Notes on Nuclear receptors: https://www.biologyexams4u.com/2023/01/nuclear-receptors-type-i-and-type-ii.html
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00:00| Introduction
00:20| What are Intracellular receptors?
00:42| What is Type I receptor? with example
01:16| What is Type II receptor? with example
01:45| 48 Human Nuclear receptors tree
01:55| Nuclear receptor structural domains
02:22| What is a transactivation factor?
03:54| Type I Nuclear receptor signaling or pathway
06:18| Type II Nuclear receptor signaling or pathway
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https://wn.com/Intracellular_Receptor_Signaling_||_Type_I_And_Type_Ii_Nuclear_Receptor_Signaling_And_Structure
8 Minute video on Intracellular Receptor Signaling, Structure of Nuclear receptor, Type I and Type II Nuclear receptor signaling
Check your Understanding: Diagram quiz on cell signaling: shorturl.at/afhsD
Notes on Nuclear receptors: https://www.biologyexams4u.com/2023/01/nuclear-receptors-type-i-and-type-ii.html
▶Enroll now. Our free certificate course on Introduction to Recombinant DNA Technology
https://alison.com/course/introduction-to-recombinant-dna-technology?utm_source=alison_user&utm_medium=affiliates&utm_campaign=22177687
Please consider subscribing using the link: https://bit.ly/3kG2kKf
00:00| Introduction
00:20| What are Intracellular receptors?
00:42| What is Type I receptor? with example
01:16| What is Type II receptor? with example
01:45| 48 Human Nuclear receptors tree
01:55| Nuclear receptor structural domains
02:22| What is a transactivation factor?
03:54| Type I Nuclear receptor signaling or pathway
06:18| Type II Nuclear receptor signaling or pathway
Please share, subscribe and like ... Thank you so much:) @biologyexams4u
============================================================
We really appreciate your support 👍 Thank you so much:) @biologyexams4u
📙Introduction to Recombinant DNA Technology – Download free E Book
https://www.biologyexams4u.com/2022/09/enroll-now-new-online-course-on.html
============================================================
Biologyexams4u network is dedicated to create and share simplified biology learning resources to students as well as teachers globally. We firmly believe that our simplified content will help you to improve your understanding and generate curiosity and interest in Life Sciences.
#biologyexams4uvideos #simplebiologyvideos #biology #science #usmle #apbio #igcsebiology #neetpg #medical #clep #mcat #neet #alevelbiology #csirlifescience #neetshorts #cellbiology #cellsignaling #usmle #receptor #alevelbiology #cell #science #receptores #nuclearreceptors #medicalstudent #nursing #nursingnotes #neetpg #receptors #gpcr #pharmacy #pharmacology #pharmacologyclass #neetpg #mcat #pharmacologymadeeasy
Thank you so much for your consistent support.
Visit our Websites
*About Biology Exams, Preparation tips, and Notes: https://www.biologyexams4u.com/
*MCQ in biology: Wide collection on Multiple Choice in Biology
https://www.mcqbiology.com/
*Interactive Biology Quiz
https://www.quizbiology.com/
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https://www.majordifferences.com/
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- published: 16 Oct 2022
- views: 11993
3:00
Gene Music using Protein Sequence of NCOA3 "NUCLEAR RECEPTOR COACTIVATOR 3"
Shop NCOA3 - https://www.redbubble.com/people/genemusic/works/56154066-ncoa3?asc=u
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Gene...
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Gene Music Studio - A channel to taste (visually & musically) gene information (particularly protein sequences)
Gene Music using Protein Sequence of NCOA3 'NUCLEAR RECEPTOR COACTIVATOR 3'
https://wn.com/Gene_Music_Using_Protein_Sequence_Of_Ncoa3_Nuclear_Receptor_Coactivator_3
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Gene Music Studio - A channel to taste (visually & musically) gene information (particularly protein sequences)
Gene Music using Protein Sequence of NCOA3 'NUCLEAR RECEPTOR COACTIVATOR 3'
- published: 09 Nov 2017
- views: 27
45:53
Nuclear Receptors and Lipid Binding Proteins
Scientific Research Symposium - Department of Pharmacology (Part 3), Noa Noy, Ph.D. Recorded on 5-11-2007.
Scientific Research Symposium - Department of Pharmacology (Part 3), Noa Noy, Ph.D. Recorded on 5-11-2007.
https://wn.com/Nuclear_Receptors_And_Lipid_Binding_Proteins
Scientific Research Symposium - Department of Pharmacology (Part 3), Noa Noy, Ph.D. Recorded on 5-11-2007.
- published: 17 Mar 2008
- views: 4972
57:55
Mod-03 Lec-23 Mechanism of transcriptional activation by nuclear receptors
Eukaryotic Gene Expression:Basics & Benefits by Prof.P N RANGARAJAN,Department of Biochemistry,IISC Bangalore. For more details on NPTEL visit http://nptel.iitm...
Eukaryotic Gene Expression:Basics & Benefits by Prof.P N RANGARAJAN,Department of Biochemistry,IISC Bangalore. For more details on NPTEL visit http://nptel.iitm.ac.in
https://wn.com/Mod_03_Lec_23_Mechanism_Of_Transcriptional_Activation_By_Nuclear_Receptors
Eukaryotic Gene Expression:Basics & Benefits by Prof.P N RANGARAJAN,Department of Biochemistry,IISC Bangalore. For more details on NPTEL visit http://nptel.iitm.ac.in
- published: 27 Sep 2011
- views: 4917
16:14
Nuclear Receptor Signaling-NRS |Structure & Function|Mnemonics to Learn -Drugs Follow |Transcription
Nuclear receptors are activated by lipid-soluble signals (e.g., steroid hormones) that cross the plasma membrane. Once activated, most function as transcription...
Nuclear receptors are activated by lipid-soluble signals (e.g., steroid hormones) that cross the plasma membrane. Once activated, most function as transcription factors to control gene expression for numerous biological processes.
Nuclear receptors are a family of ligand-regulated transcription factors that are activated by steroid hormones, such as estrogen and progesterone, and various other lipid-soluble signals, including retinoic acid, oxysterols, and thyroid hormone . Unlike most intercellular messengers, the ligands can cross the plasma membrane and directly interact with nuclear receptors inside the cell , rather than having to act via cell surface receptors. Once activated, nuclear receptors directly regulate transcription of genes that control a wide variety of biological processes, including cell proliferation, development, metabolism, and reproduction. Although nuclear receptors primarily function as transcription factors, some have also been found to regulate cellular functions within the cytoplasm. For example, estrogens act through the estrogen receptor in the cytoplasm of endothelial cells to rapidly activate signaling pathways that control vascular tone and endothelial cell migration.
Ligands that bind to and activate nuclear receptors include lipophilic substances such as endogenous hormones, vitamins A and D, and xenobiotic endocrine disruptors.
Mechanism of class I nuclear receptor action. A class I nuclear receptor (NR), in the absence of ligand, is located in the cytosol. Hormone binding to the NR triggers dissociation of heat shock proteins (HSP), dimerization, and translocation to the nucleus, where the NR binds to a specific sequence of DNA known as a hormone response element (HRE). The nuclear receptor DNA complex in turn recruits other proteins that are responsible for transcription of downstream DNA into mRNA, which is eventually translated into protein, which results in a change in cell function.
Mechanism of class II nuclear receptor action. A class II nuclear receptor (NR), regardless of ligand-binding status, is located in the nucleus bound to DNA. For the purpose of illustration, the nuclear receptor shown here is the thyroid hormone receptor (TR) heterodimerized to the RXR. In the absence of ligand, the TR is bound to corepressor protein. Ligand binding to TR causes a dissociation of corepressor and recruitment of coactivator protein, which, in turn, recruits additional proteins such as RNA polymerase that are responsible for transcription of downstream DNA into RNA and eventually protein.
Type III nuclear receptors (principally NR subfamily 2) are similar to type I receptors in that both classes bind to DNA as homodimers. However, type III nuclear receptors, in contrast to type I, bind to direct repeat instead of inverted repeat HREs.
Type IV nuclear receptors bind either as monomers or dimers, but only a single DNA binding domain of the receptor binds to a single half site HRE. Examples of type IV receptors are found in most of the NR subfamilies.
https://wn.com/Nuclear_Receptor_Signaling_Nrs_|Structure_Function|Mnemonics_To_Learn_Drugs_Follow_|Transcription
Nuclear receptors are activated by lipid-soluble signals (e.g., steroid hormones) that cross the plasma membrane. Once activated, most function as transcription factors to control gene expression for numerous biological processes.
Nuclear receptors are a family of ligand-regulated transcription factors that are activated by steroid hormones, such as estrogen and progesterone, and various other lipid-soluble signals, including retinoic acid, oxysterols, and thyroid hormone . Unlike most intercellular messengers, the ligands can cross the plasma membrane and directly interact with nuclear receptors inside the cell , rather than having to act via cell surface receptors. Once activated, nuclear receptors directly regulate transcription of genes that control a wide variety of biological processes, including cell proliferation, development, metabolism, and reproduction. Although nuclear receptors primarily function as transcription factors, some have also been found to regulate cellular functions within the cytoplasm. For example, estrogens act through the estrogen receptor in the cytoplasm of endothelial cells to rapidly activate signaling pathways that control vascular tone and endothelial cell migration.
Ligands that bind to and activate nuclear receptors include lipophilic substances such as endogenous hormones, vitamins A and D, and xenobiotic endocrine disruptors.
Mechanism of class I nuclear receptor action. A class I nuclear receptor (NR), in the absence of ligand, is located in the cytosol. Hormone binding to the NR triggers dissociation of heat shock proteins (HSP), dimerization, and translocation to the nucleus, where the NR binds to a specific sequence of DNA known as a hormone response element (HRE). The nuclear receptor DNA complex in turn recruits other proteins that are responsible for transcription of downstream DNA into mRNA, which is eventually translated into protein, which results in a change in cell function.
Mechanism of class II nuclear receptor action. A class II nuclear receptor (NR), regardless of ligand-binding status, is located in the nucleus bound to DNA. For the purpose of illustration, the nuclear receptor shown here is the thyroid hormone receptor (TR) heterodimerized to the RXR. In the absence of ligand, the TR is bound to corepressor protein. Ligand binding to TR causes a dissociation of corepressor and recruitment of coactivator protein, which, in turn, recruits additional proteins such as RNA polymerase that are responsible for transcription of downstream DNA into RNA and eventually protein.
Type III nuclear receptors (principally NR subfamily 2) are similar to type I receptors in that both classes bind to DNA as homodimers. However, type III nuclear receptors, in contrast to type I, bind to direct repeat instead of inverted repeat HREs.
Type IV nuclear receptors bind either as monomers or dimers, but only a single DNA binding domain of the receptor binds to a single half site HRE. Examples of type IV receptors are found in most of the NR subfamilies.
- published: 26 Mar 2020
- views: 2236
6:34
Receptors Regulating Gene Expression or Nuclear Receptors (Pharmacodynamics Part 13) | Dr. Shikha
Receptors Regulating Gene Expression or Nuclear Receptors (Pharmacodynamics Part 13) by Dr. Shikha Parmar
Nuclear Receptors
Nuclear receptors (also known as nu...
Receptors Regulating Gene Expression or Nuclear Receptors (Pharmacodynamics Part 13) by Dr. Shikha Parmar
Nuclear Receptors
Nuclear receptors (also known as nuclear hormone receptors) are a large family of transcription factors that bind directly to DNA to regulate the expression of target genes. They regulate the cellular response to hormones such as sex steroids, vitamin D3, adrenal steroids and other metabolic ligands, and are involved in metabolism, development and reproduction.
The nuclear receptor superfamily is classified by sequence alignment and phylogenetic tree construction into six main subfamilies:
Thyroid Hormone Receptor-like: includes thyroid receptor, retinoic acid receptor, PPAR, LXR, FXR, VDR, PXR and CAR
Retinoid X Receptor-like: includes RXR
Estrogen Receptor-like (also known as steroid hormone receptors): includes receptors for estrogen (ER), androgen, glucocorticoid, mineralocorticoid and progesterone
Nerve Growth Factor IB-like
Steroidogenic Factor-like
Germ Cell Nuclear Factor-like
Regulation and Disease
Of the 48 nuclear receptors in the human genome, 24 are ligand-dependent transcription factors. The activity of endogenous ligands on nuclear receptors is normally to upregulate gene expression. Upon ligand-binding a conformation change results in the receptor that regulates the recruitment of coregulators and chromatin-modifying machinery. The majority of nuclear receptors bind-sequence specific promoter elements on target genes either as monomers, homodimers or heterodimers with RXR.
Nuclear receptors are important mediators of disease in general, with receptor mutations responsible for a range of diseases. Mutations in the androgen receptor can cause infertility and prostate cancer; mutations in PPAR can result in colon cancer and diabetes mellitus; and mutations in the estrogen receptor can cause breast cancer.
https://wn.com/Receptors_Regulating_Gene_Expression_Or_Nuclear_Receptors_(Pharmacodynamics_Part_13)_|_Dr._Shikha
Receptors Regulating Gene Expression or Nuclear Receptors (Pharmacodynamics Part 13) by Dr. Shikha Parmar
Nuclear Receptors
Nuclear receptors (also known as nuclear hormone receptors) are a large family of transcription factors that bind directly to DNA to regulate the expression of target genes. They regulate the cellular response to hormones such as sex steroids, vitamin D3, adrenal steroids and other metabolic ligands, and are involved in metabolism, development and reproduction.
The nuclear receptor superfamily is classified by sequence alignment and phylogenetic tree construction into six main subfamilies:
Thyroid Hormone Receptor-like: includes thyroid receptor, retinoic acid receptor, PPAR, LXR, FXR, VDR, PXR and CAR
Retinoid X Receptor-like: includes RXR
Estrogen Receptor-like (also known as steroid hormone receptors): includes receptors for estrogen (ER), androgen, glucocorticoid, mineralocorticoid and progesterone
Nerve Growth Factor IB-like
Steroidogenic Factor-like
Germ Cell Nuclear Factor-like
Regulation and Disease
Of the 48 nuclear receptors in the human genome, 24 are ligand-dependent transcription factors. The activity of endogenous ligands on nuclear receptors is normally to upregulate gene expression. Upon ligand-binding a conformation change results in the receptor that regulates the recruitment of coregulators and chromatin-modifying machinery. The majority of nuclear receptors bind-sequence specific promoter elements on target genes either as monomers, homodimers or heterodimers with RXR.
Nuclear receptors are important mediators of disease in general, with receptor mutations responsible for a range of diseases. Mutations in the androgen receptor can cause infertility and prostate cancer; mutations in PPAR can result in colon cancer and diabetes mellitus; and mutations in the estrogen receptor can cause breast cancer.
- published: 11 Apr 2022
- views: 5393
3:37
Nuclear Receptor |Transcription Factor |Intercellular Receptor | Receptor Regulating Gene Expression
Nuclear receptors are a class of transcription factors that play a crucial role in regulating gene expression in eukaryotic cells. They are a diverse family of ...
Nuclear receptors are a class of transcription factors that play a crucial role in regulating gene expression in eukaryotic cells. They are a diverse family of proteins found in the cell nucleus, and their primary function is to sense and respond to various signaling molecules, including hormones, vitamins, and other small molecules.
Structure of Nuclear Receptors:
Nuclear receptors are modular proteins with a characteristic domain structure. The typical structure of a nuclear receptor consists of several domains, including:
N-terminal domain (NTD): The N-terminal domain is variable in length and sequence among different nuclear receptors. It is involved in interactions with co-regulatory proteins and can modulate the transcriptional activity of the receptor.
DNA-binding domain (DBD): The DBD is a highly conserved region that allows the nuclear receptor to bind to specific DNA sequences called hormone response elements (HREs) within the promoter regions of target genes. The DBD contains two zinc fingers that facilitate DNA binding.
Hinge region: The hinge region connects the DBD to the ligand-binding domain (LBD) and provides flexibility for the receptor's conformational changes.
Ligand-binding domain (LBD): The LBD is responsible for ligand recognition and binding. It contains a ligand-binding pocket where specific hormones or other ligands can bind, inducing conformational changes in the receptor and facilitating its transcriptional activity.
Mechanism of Action:
The action of nuclear receptors involves a series of steps, including ligand binding, receptor activation, and modulation of gene expression. Here is a general overview of the mechanism:
Ligand binding: When a specific hormone or ligand binds to the LBD of a nuclear receptor, it induces conformational changes that stabilize the receptor-ligand complex.
Receptor activation: Ligand binding triggers a cascade of events that result in the activation of the nuclear receptor. This activation involves the dissociation of co-repressor proteins and the recruitment of co-activator proteins to the receptor complex.
DNA binding: Activated nuclear receptors translocate into the nucleus and bind to specific DNA sequences called hormone response elements (HREs) within the promoter regions of target genes. The binding of the receptor to HREs promotes or inhibits the transcription of target genes.
Transcriptional regulation: Once bound to HREs, the nuclear receptor can interact with other transcriptional machinery, including RNA polymerase and co-regulatory proteins, to modulate gene expression. This interaction can result in the activation or repression of target genes, leading to the production of specific proteins or the inhibition of their synthesis.
Feedback regulation: Nuclear receptors can also regulate their own expression or the expression of other components in their signaling pathways, creating feedback loops that fine-tune gene expression and maintain homeostasis.
Roles and Functions:
Nuclear receptors have diverse roles and functions in various physiological processes, including:
Hormone regulation: Many nuclear receptors serve as hormone receptors and are involved in the regulation of hormone signaling pathways. Examples include the estrogen receptor, androgen receptor, progesterone receptor, and thyroid hormone receptor.
Metabolism: Several nuclear receptors play crucial roles in regulating metabolism, including lipid metabolism, glucose homeostasis, and energy balance. Notable examples include the peroxisome proliferator-activated receptors (PPARs) and the liver X receptors (LXRs).
Immune response: Some nuclear receptors, such as the glucocorticoid receptor (GR) and the peroxisome proliferator-activated receptor gamma (PPARγ), play important roles in regulating immune responses. They can modulate the expression of genes involved in inflammation, immune cell differentiation, and immune system homeostasis.
Reproduction and fertility: Nuclear receptors are involved in various aspects of reproductive physiology.
Xenobiotic metabolism: Nuclear receptors also participate in the metabolism and detoxification of xenobiotics, which are foreign substances that enter the body. For example, the pregnane X receptor (PXR) and the constitutive androstane receptor (CAR) are involved in the regulation of drug metabolism and the response to environmental toxins.
Circadian rhythm regulation: Nuclear receptors contribute to the regulation of circadian rhythms, which are the internal biological clocks that synchronize various physiological processes with the 24-hour day-night cycle.
Cell proliferation and differentiation: Nuclear receptors play critical roles in controlling cell proliferation and differentiation processes.
Therapeutic targets: Nuclear receptors are important therapeutic targets for several diseases.
#pharmacology #pharmacy #drug #mbbs #pharmacokinetics #anatomy #healtheducation #pharmacodynamics #classify #principal #clearpharma #net #neetpg
https://wn.com/Nuclear_Receptor_|Transcription_Factor_|Intercellular_Receptor_|_Receptor_Regulating_Gene_Expression
Nuclear receptors are a class of transcription factors that play a crucial role in regulating gene expression in eukaryotic cells. They are a diverse family of proteins found in the cell nucleus, and their primary function is to sense and respond to various signaling molecules, including hormones, vitamins, and other small molecules.
Structure of Nuclear Receptors:
Nuclear receptors are modular proteins with a characteristic domain structure. The typical structure of a nuclear receptor consists of several domains, including:
N-terminal domain (NTD): The N-terminal domain is variable in length and sequence among different nuclear receptors. It is involved in interactions with co-regulatory proteins and can modulate the transcriptional activity of the receptor.
DNA-binding domain (DBD): The DBD is a highly conserved region that allows the nuclear receptor to bind to specific DNA sequences called hormone response elements (HREs) within the promoter regions of target genes. The DBD contains two zinc fingers that facilitate DNA binding.
Hinge region: The hinge region connects the DBD to the ligand-binding domain (LBD) and provides flexibility for the receptor's conformational changes.
Ligand-binding domain (LBD): The LBD is responsible for ligand recognition and binding. It contains a ligand-binding pocket where specific hormones or other ligands can bind, inducing conformational changes in the receptor and facilitating its transcriptional activity.
Mechanism of Action:
The action of nuclear receptors involves a series of steps, including ligand binding, receptor activation, and modulation of gene expression. Here is a general overview of the mechanism:
Ligand binding: When a specific hormone or ligand binds to the LBD of a nuclear receptor, it induces conformational changes that stabilize the receptor-ligand complex.
Receptor activation: Ligand binding triggers a cascade of events that result in the activation of the nuclear receptor. This activation involves the dissociation of co-repressor proteins and the recruitment of co-activator proteins to the receptor complex.
DNA binding: Activated nuclear receptors translocate into the nucleus and bind to specific DNA sequences called hormone response elements (HREs) within the promoter regions of target genes. The binding of the receptor to HREs promotes or inhibits the transcription of target genes.
Transcriptional regulation: Once bound to HREs, the nuclear receptor can interact with other transcriptional machinery, including RNA polymerase and co-regulatory proteins, to modulate gene expression. This interaction can result in the activation or repression of target genes, leading to the production of specific proteins or the inhibition of their synthesis.
Feedback regulation: Nuclear receptors can also regulate their own expression or the expression of other components in their signaling pathways, creating feedback loops that fine-tune gene expression and maintain homeostasis.
Roles and Functions:
Nuclear receptors have diverse roles and functions in various physiological processes, including:
Hormone regulation: Many nuclear receptors serve as hormone receptors and are involved in the regulation of hormone signaling pathways. Examples include the estrogen receptor, androgen receptor, progesterone receptor, and thyroid hormone receptor.
Metabolism: Several nuclear receptors play crucial roles in regulating metabolism, including lipid metabolism, glucose homeostasis, and energy balance. Notable examples include the peroxisome proliferator-activated receptors (PPARs) and the liver X receptors (LXRs).
Immune response: Some nuclear receptors, such as the glucocorticoid receptor (GR) and the peroxisome proliferator-activated receptor gamma (PPARγ), play important roles in regulating immune responses. They can modulate the expression of genes involved in inflammation, immune cell differentiation, and immune system homeostasis.
Reproduction and fertility: Nuclear receptors are involved in various aspects of reproductive physiology.
Xenobiotic metabolism: Nuclear receptors also participate in the metabolism and detoxification of xenobiotics, which are foreign substances that enter the body. For example, the pregnane X receptor (PXR) and the constitutive androstane receptor (CAR) are involved in the regulation of drug metabolism and the response to environmental toxins.
Circadian rhythm regulation: Nuclear receptors contribute to the regulation of circadian rhythms, which are the internal biological clocks that synchronize various physiological processes with the 24-hour day-night cycle.
Cell proliferation and differentiation: Nuclear receptors play critical roles in controlling cell proliferation and differentiation processes.
Therapeutic targets: Nuclear receptors are important therapeutic targets for several diseases.
#pharmacology #pharmacy #drug #mbbs #pharmacokinetics #anatomy #healtheducation #pharmacodynamics #classify #principal #clearpharma #net #neetpg
- published: 27 Jun 2023
- views: 90