Boiling water-catalyzed neutral and selective N-Boc deprotection
* Corresponding authors a State key Laboratory of Elemento-organic Chemistry, Nankai University, Tianjin 300071, China E-mail: qujin@nankai.edu.cn Fax: +86-22-23499254 Tel: +86-22-23499247 A general protocol for removing Boc groups from various types of nitrogen is reported and a preliminary investigation of the reaction mechanism indicates that water acts as a dual acid/base catalyst at elevated
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