Dermatosis Erythrosquamous
Dermatosis Erythrosquamous
Dermatosis Erythrosquamous
ERYTHROSQUAMOUS
Def: disease are characterized by erythema
and scale (squama)
1.
2.
3.
4.
5.
6.
PSORIASIS
PARAPSORIASIS
PITYRIASIS ROSEA
DERMATITIS SEBORHEIC
ERYTHRODERMIA
LUPUS VULGARIS
PSORIASIS
Clasification :
- Psoriasis Vulgaris :- Acut Guttate
- Chronic Plaque
- Palmo Plantar
- Psoriatic Erythroderma
- Pustular Psoriasis
PSORIASIS VULGARIS
Pathogenesis:
abnormality in psoriasis :
alteration of the cell kinetic of
keratinocytes
Physic exam :
of
PUSTULAR PSORIASIS
Def :characterized by pustules arising on
normal/inflamed, erythematous skin.
2 types : generilized & palmo-plantar
Palmo-plantar :
Def : - chronic, relapsing eruption limited to the palms
&soles.
- steril, yelow, deep-seated pustules dusky-red
crusts
-Symp :tingling, burning iching
- Skin lessions : pustules 2-5 mm, deep-seated, duskyred macules crusts in erythema, scaling
or normal skin
- DD : T Manus, Dyshidrotic eczematous Dermatitis,
HSV Inf
Management :
Topical : - steroid agent in oint base
- hydrocolloid dressing
- anthralin
- analog vit D (calciprotriene 0,05%)cream
- Tacrolimus 0,1%
-Tazarotene (retinoid 0,05-0,1%)
- PUVA
Scalp : tar/ketokonazol shampoo
betametason valerat lot
Oral : cytostatic : Mtx 3x2,5mg/w 3x5mg/w
Levodopa 2x250mg-3x500mg/d
DDS 2x100mg/d
Etretinate 1mg/kgbw/d
Cyclosporin 6mg/kgbw/d
PARAPSORIASIS
PARAPSORIASIS en PLAQUES
2 types : 1. Small-plaque parapsoriasis
2. Large-plaque parapsoriasis
Small-plaque parapsoriasis
(digitate dermatosis, or chronic superficial dermatitis)
- Def : chronic disease characterized by slightly
elevated
plaques and scales
Physical exam : round, oval, erythematous,
yellowish,
slightly elevated plaques, <5 cm with slight scale and wrinkled
surface with
cigarette-paper appearance.
DD : Pityriasis Rosea, Large-plaque parapsoriasis
TX: Lubricant/ topical steroid
PUVA
Large-plaque parapsoriasis
*Lessions disappear after sun exposure (in
summer), recur (in fall & winter)
*Middle age
Physical exam :
- barely elevated, erythematous, dusky- red,
sometime yellowish plaques with smooth or
slightly scalling surface.
>10 cm, well defined
- predilection : trunk, buttock, breasts & extremities
DD : early stages of CTCL
Prog : persist for life
Tx : topical glucocorticoid, PUVA
PITYRIASIS ROSEA
Def: acute exanthematous with distinctive
morphology & often with characteristic self-limited
course
first: single primary/herald plaque
1-2w
generalized secondary eruption
(typical distribution)
6w
remits spontaneously
Etiol : ? herpes virus type-7
Pysical exam :
- Herald patch : oval, slightly raised plaque 25cm, salmon-red, fine colarette scale at
periphery
- Exanthem : fine scaling papules & plaques
with marginal collarette.Characteristic dist:
long axes of the oval lesion following the
lines of cleavage in a christmas tree pattern
Typical P Rosea : - only on the face & neck, herald
patch may be (-)
DD : Drug neruption
Secondary Syphilis
Guttate psoriasis
Erythema Multiforme
Course : spontaneous remission 6-12w
Tx : symptomatic
SEBORHEIC DERMATITIS
Def :very common chronic dermatitis characterized by redness
& scaling sebaceous gland more active:face, scalp,body
DEF
Physical exam :
orange-red or gray-white skin often with greasy or
white dry scaling macules & papules (5-20mm) sticky c
rusts & fissures (fold behind the external ear), scalp marked
scaling (dandruff)
Tx : topical :glucocorticoid, ketokonazol 2%, tar, tacrolimus
UV radiation
syst : 13-cis retinoic acid 1mg/kgbw
ERYTRODERMA
Physical exam :
* Dermatitis & lymfoma/leucemia acute erythema patch
12-48 h
erythroderma
(fever, shivers, hot & cold)
2-6 d
dequamation
w
hair loss (scalp & body)
onycolysis,thicken nail
*History most important
Management :
- Topical : water bath + bath oil bland
emollients
- Oral : - glucocorticoid remission
*Tx syst & topical underlying condition