What Actually Causes High Cholesterol? | Dr. Robert Lustig
Levels Advisor Robert Lustig, MD, explains the different types of cholesterol and what drives cardiovascular disease.
Cholesterol is necessary for the body. In fact, our bodies have a method for manufacturing it. But cholesterol gets a bad rap because of confusion about the types—and which type actually drives cardiovascular disease.
Understanding the different types of cholesterol can help you tailor your diet and lifestyle habits for better metabolic health. Keep in mind that the pattern of all types of cholesterol taken together, rather than individual levels, matters the most.
Types of cholesterol
- high-density lipoprotein (HDL) cholesterol: “good” cholesterol
- low-density lipoprotein (LDL) cholesterol—two types: large buoyant (lbLDL) and small dense (sdLDL)
- very low-density li...
published: 21 Jul 2024
DIGESTIVE ENZYMES: LIPASES 2
Description
published: 28 Mar 2014
Lipoprotein lipase
Lipoprotein lipase is a member of the lipase gene family, which includes pancreatic lipase, hepatic lipase, and endothelial lipase. It is a water-soluble enzyme that hydrolyzes triglycerides in lipoproteins, such as those found in chylomicrons and very low-density lipoproteins, into two free fatty acids and one monoacylglycerol molecule. It is also involved in promoting the cellular uptake of chylomicron remnants, cholesterol-rich lipoproteins, and free fatty acids. LPL requires ApoC-II as a cofactor.
LPL is attached to the luminal surface of endothelial cells in capillaries by the protein glycosylphosphatidylinositol HDL-binding protein 1 and by heparin sulfated proteoglycans. It is most widely distributed in adipose, heart, and skeletal muscle tissue, as well as in lactating mammary glan...
published: 22 Oct 2015
Subcellular Therapeutic Targeting of Common Lipid Disorders - Dr. Sotirios Tsimikas
published: 13 Oct 2020
Lipid Management in 2019: From Inclisaran to ANGPTL3- Evolution or Revolution? - Dr. Robert Rosenson
Top Ten Topics in Clinical Cardiology
published: 21 Oct 2019
Lipids and Insulin Resistance - Dr. William Cromwell
The video that has been distributed all over the country and is a must see for interested physicians. Dr. William Cromwell, MD, FAHA, FNLA, course on lipids and insulin resistance.
Have topics you would like to see? Comment below!
Website ---▶︎https://www.specialtyhealthwellness.com/
Facebook ---▶︎ https://www.facebook.com/specialtyhea...
Instagram ---▶︎ specialtyhealthwellness
Email ---▶︎ [email protected]
published: 21 Jan 2012
HDL Scientific Animation
3D animation based on the research of Dr. Hamid Razzaghi, PhD, FAHA at the University of Colorado at Denver. The animation illustrates the Interaction of Endothelial Lipase with High Density Lipoproteins. Contact [email protected] or visit our website www.nightmill.com to learn more.
published: 12 Jun 2012
Update on Triglycerides
Daniel Soffer, MD
University of Pennsylvania
published: 24 Mar 2023
Medical vocabulary: What does Lipoprotein Lipase mean
Levels Advisor Robert Lustig, MD, explains the different types of cholesterol and what drives cardiovascular disease.
Cholesterol is necessary for the body. In...
Levels Advisor Robert Lustig, MD, explains the different types of cholesterol and what drives cardiovascular disease.
Cholesterol is necessary for the body. In fact, our bodies have a method for manufacturing it. But cholesterol gets a bad rap because of confusion about the types—and which type actually drives cardiovascular disease.
Understanding the different types of cholesterol can help you tailor your diet and lifestyle habits for better metabolic health. Keep in mind that the pattern of all types of cholesterol taken together, rather than individual levels, matters the most.
Types of cholesterol
- high-density lipoprotein (HDL) cholesterol: “good” cholesterol
- low-density lipoprotein (LDL) cholesterol—two types: large buoyant (lbLDL) and small dense (sdLDL)
- very low-density lipoprotein (VLDL): represented as triglycerides
Understanding the types of LDL:
- lbLDL: neutral when it comes to cardiovascular health and is elevated via fat consumption
- sdLDL: drives atherosclerosis and is elevated via sugar consumption
✅ What you can do:
- Reduce sugar consumption to minimize sdLDL.
- Get regular exercise to elevate HDL.
#metabolichealth #cholesterol #fat #sugar
👋 WHO WE ARE:
Levels helps you see how food affects your health. With real-time, personalized data gathered through biosensors like continuous glucose monitors (CGM), you learn which diet and lifestyle choices improve your metabolic health so you can live a longer, fuller, healthier life.
🔗 LINKS:
Become a Levels member: https://levels.link/shorts
Subscribe here on YouTube: https://youtube.com/@levels?sub_confirmation=1
Levels Advisor Robert Lustig, MD, explains the different types of cholesterol and what drives cardiovascular disease.
Cholesterol is necessary for the body. In fact, our bodies have a method for manufacturing it. But cholesterol gets a bad rap because of confusion about the types—and which type actually drives cardiovascular disease.
Understanding the different types of cholesterol can help you tailor your diet and lifestyle habits for better metabolic health. Keep in mind that the pattern of all types of cholesterol taken together, rather than individual levels, matters the most.
Types of cholesterol
- high-density lipoprotein (HDL) cholesterol: “good” cholesterol
- low-density lipoprotein (LDL) cholesterol—two types: large buoyant (lbLDL) and small dense (sdLDL)
- very low-density lipoprotein (VLDL): represented as triglycerides
Understanding the types of LDL:
- lbLDL: neutral when it comes to cardiovascular health and is elevated via fat consumption
- sdLDL: drives atherosclerosis and is elevated via sugar consumption
✅ What you can do:
- Reduce sugar consumption to minimize sdLDL.
- Get regular exercise to elevate HDL.
#metabolichealth #cholesterol #fat #sugar
👋 WHO WE ARE:
Levels helps you see how food affects your health. With real-time, personalized data gathered through biosensors like continuous glucose monitors (CGM), you learn which diet and lifestyle choices improve your metabolic health so you can live a longer, fuller, healthier life.
🔗 LINKS:
Become a Levels member: https://levels.link/shorts
Subscribe here on YouTube: https://youtube.com/@levels?sub_confirmation=1
Lipoprotein lipase is a member of the lipase gene family, which includes pancreatic lipase, hepatic lipase, and endothelial lipase. It is a water-soluble enzyme...
Lipoprotein lipase is a member of the lipase gene family, which includes pancreatic lipase, hepatic lipase, and endothelial lipase. It is a water-soluble enzyme that hydrolyzes triglycerides in lipoproteins, such as those found in chylomicrons and very low-density lipoproteins, into two free fatty acids and one monoacylglycerol molecule. It is also involved in promoting the cellular uptake of chylomicron remnants, cholesterol-rich lipoproteins, and free fatty acids. LPL requires ApoC-II as a cofactor.
LPL is attached to the luminal surface of endothelial cells in capillaries by the protein glycosylphosphatidylinositol HDL-binding protein 1 and by heparin sulfated proteoglycans. It is most widely distributed in adipose, heart, and skeletal muscle tissue, as well as in lactating mammary glands.
This video is targeted to blind users.
Attribution:
Article text available under CC-BY-SA
Creative Commons image source in video
Lipoprotein lipase is a member of the lipase gene family, which includes pancreatic lipase, hepatic lipase, and endothelial lipase. It is a water-soluble enzyme that hydrolyzes triglycerides in lipoproteins, such as those found in chylomicrons and very low-density lipoproteins, into two free fatty acids and one monoacylglycerol molecule. It is also involved in promoting the cellular uptake of chylomicron remnants, cholesterol-rich lipoproteins, and free fatty acids. LPL requires ApoC-II as a cofactor.
LPL is attached to the luminal surface of endothelial cells in capillaries by the protein glycosylphosphatidylinositol HDL-binding protein 1 and by heparin sulfated proteoglycans. It is most widely distributed in adipose, heart, and skeletal muscle tissue, as well as in lactating mammary glands.
This video is targeted to blind users.
Attribution:
Article text available under CC-BY-SA
Creative Commons image source in video
The video that has been distributed all over the country and is a must see for interested physicians. Dr. William Cromwell, MD, FAHA, FNLA, course on lipids and...
The video that has been distributed all over the country and is a must see for interested physicians. Dr. William Cromwell, MD, FAHA, FNLA, course on lipids and insulin resistance.
Have topics you would like to see? Comment below!
Website ---▶︎https://www.specialtyhealthwellness.com/
Facebook ---▶︎ https://www.facebook.com/specialtyhea...
Instagram ---▶︎ specialtyhealthwellness
Email ---▶︎ [email protected]
The video that has been distributed all over the country and is a must see for interested physicians. Dr. William Cromwell, MD, FAHA, FNLA, course on lipids and insulin resistance.
Have topics you would like to see? Comment below!
Website ---▶︎https://www.specialtyhealthwellness.com/
Facebook ---▶︎ https://www.facebook.com/specialtyhea...
Instagram ---▶︎ specialtyhealthwellness
Email ---▶︎ [email protected]
3D animation based on the research of Dr. Hamid Razzaghi, PhD, FAHA at the University of Colorado at Denver. The animation illustrates the Interaction of Endoth...
3D animation based on the research of Dr. Hamid Razzaghi, PhD, FAHA at the University of Colorado at Denver. The animation illustrates the Interaction of Endothelial Lipase with High Density Lipoproteins. Contact [email protected] or visit our website www.nightmill.com to learn more.
3D animation based on the research of Dr. Hamid Razzaghi, PhD, FAHA at the University of Colorado at Denver. The animation illustrates the Interaction of Endothelial Lipase with High Density Lipoproteins. Contact [email protected] or visit our website www.nightmill.com to learn more.
Levels Advisor Robert Lustig, MD, explains the different types of cholesterol and what drives cardiovascular disease.
Cholesterol is necessary for the body. In fact, our bodies have a method for manufacturing it. But cholesterol gets a bad rap because of confusion about the types—and which type actually drives cardiovascular disease.
Understanding the different types of cholesterol can help you tailor your diet and lifestyle habits for better metabolic health. Keep in mind that the pattern of all types of cholesterol taken together, rather than individual levels, matters the most.
Types of cholesterol
- high-density lipoprotein (HDL) cholesterol: “good” cholesterol
- low-density lipoprotein (LDL) cholesterol—two types: large buoyant (lbLDL) and small dense (sdLDL)
- very low-density lipoprotein (VLDL): represented as triglycerides
Understanding the types of LDL:
- lbLDL: neutral when it comes to cardiovascular health and is elevated via fat consumption
- sdLDL: drives atherosclerosis and is elevated via sugar consumption
✅ What you can do:
- Reduce sugar consumption to minimize sdLDL.
- Get regular exercise to elevate HDL.
#metabolichealth #cholesterol #fat #sugar
👋 WHO WE ARE:
Levels helps you see how food affects your health. With real-time, personalized data gathered through biosensors like continuous glucose monitors (CGM), you learn which diet and lifestyle choices improve your metabolic health so you can live a longer, fuller, healthier life.
🔗 LINKS:
Become a Levels member: https://levels.link/shorts
Subscribe here on YouTube: https://youtube.com/@levels?sub_confirmation=1
Lipoprotein lipase is a member of the lipase gene family, which includes pancreatic lipase, hepatic lipase, and endothelial lipase. It is a water-soluble enzyme that hydrolyzes triglycerides in lipoproteins, such as those found in chylomicrons and very low-density lipoproteins, into two free fatty acids and one monoacylglycerol molecule. It is also involved in promoting the cellular uptake of chylomicron remnants, cholesterol-rich lipoproteins, and free fatty acids. LPL requires ApoC-II as a cofactor.
LPL is attached to the luminal surface of endothelial cells in capillaries by the protein glycosylphosphatidylinositol HDL-binding protein 1 and by heparin sulfated proteoglycans. It is most widely distributed in adipose, heart, and skeletal muscle tissue, as well as in lactating mammary glands.
This video is targeted to blind users.
Attribution:
Article text available under CC-BY-SA
Creative Commons image source in video
The video that has been distributed all over the country and is a must see for interested physicians. Dr. William Cromwell, MD, FAHA, FNLA, course on lipids and insulin resistance.
Have topics you would like to see? Comment below!
Website ---▶︎https://www.specialtyhealthwellness.com/
Facebook ---▶︎ https://www.facebook.com/specialtyhea...
Instagram ---▶︎ specialtyhealthwellness
Email ---▶︎ [email protected]
3D animation based on the research of Dr. Hamid Razzaghi, PhD, FAHA at the University of Colorado at Denver. The animation illustrates the Interaction of Endothelial Lipase with High Density Lipoproteins. Contact [email protected] or visit our website www.nightmill.com to learn more.
... that binds to and blocks the function of angiopoietin-like 3 (ANGPTL3), a protein that inhibits lipoprotein lipase (LPL) and endothelial lipase (EL) and regulates circulating lipids, including LDL-C.
The role of the triglyceride-rich LDL particles was independent of the cholesterol content of LDL particles (independent of LDL-C) and the potential causality was further confirmed by genetic validation, based on the hepatic lipase gene ("LIPC").
... monoclonal antibody that binds to and blocks the function of ANGPTL3, a protein that inhibits lipoprotein lipase (LPL) and endothelial lipase (EL) and regulates circulating lipids, including LDL-C.
... monoclonal antibody that binds to and blocks the function of ANGPTL3, a protein that inhibits lipoprotein lipase (LPL) and endothelial lipase (EL) and regulates circulating lipids, including LDL-C.