-
How Lipoproteins Affect Metabolism in Diabetes
There is a strong connection between type 2 diabetes and dyslipidemia. This animation describes the lipid abnormalities commonly seen in patients with type 2 diabetes: elevated levels of triglycerides, raised small dense LDL levels, increased glycation and oxidation of LDLs and reduction of HDLs. These factors increase the risk of cardiovascular disease.
published: 16 Jul 2013
-
Metabolism | Lipoprotein Metabolism | Chylomicrons, VLDL, IDL, LDL, & HDL
Official Ninja Nerd Website: https://ninjanerd.org
Ninja Nerds!
In this lecture Professor Zach Murphy will be discussing the metabolism of lipoproteins- Lipoprotein Metabolism. During this lecture we talk specifically about chylomicrons in the exogenous pathway. We also talk about VLDL, IDL and LDL and their role in the endogenous pathway. Lastly, we discuss HDL and it's role in reverse cholesterol transport as well as normal serum cholesterol levels. We hope you enjoy this lecture and be sure to support us below!
Join this channel to get access to perks:
https://www.youtube.com/channel/UC6QYFutt9cluQ3uSM963_KQ/join
APPAREL |
We are switching merchandise suppliers.
DONATE
PATREON | https://www.patreon.com/NinjaNerdScience
PAYPAL | https://www.paypal.com/paypalme/ninjanerdscience
SOCIA...
published: 06 Jan 2018
-
Key enzymes in lipid transport
In this Express Video from the Biochemistry section, Daniel Griffin offers up a breakdown of the key enzymes in lipid transport, as described on p. 93 of First Aid for the USMLE Step 1, 2019 edition.
published: 03 Aug 2019
-
Liver and pancreatic enzymes explained | AST, ALT, GGT, ALP, Amylase & Lipase
Liver and pancreatic enzymes explained | Liver Enzymes (AST, ALT, GGT, ALP), Pancreatic Enzymes (Amylase& Lipase).
What are the liver function tests (or LFTs)?
They are a group of blood tests that help you assess the liver function (hepatocytes).
In this medical lecture, we discuss alanine transaminase (ALT, formerly SGPT), aspartate transaminase (AST, formerly SGOT), alkaline phosphatase (ALP), and gamma-glutamyl transferase (GGT)...We also mention pancreatic enzymes such as amylase (less specific because there is also a salivary amylase) and lipase (more specific).
😍🖼Animated Mnemonics (Picmonic): https://www.picmonic.com/viphookup/medicosis/
- With Picmonic, get your life back by studying less and remembering more. Medical and Nursing students say that Picmonic is the most comprehe...
published: 22 Aug 2018
-
Liver, Lipid and Lipase Biochem Changes
Starting from the top... How is fat digested, absorbed, and utilised? What forms does it take? Why don't dogs have strokes and heart attacks associated with their high cholesterol? Why is hyperlipidaemia a problem then?
published: 23 Aug 2024
-
High Liver Enzymes [ALT & AST] – What Do They Mean? – Dr.Berg
Get access to my FREE resources 👉 https://drbrg.co/3VL2pBZ
For more details on this topic, check out the full article on the website:
➡️ https://drbrg.co/3ymHxYl
Overview of Healthy Keto and Intermittent Fasting:
http://bit.ly/2B61L8j
http://bit.ly/2Ws2OIR
Take Dr. Berg's Free Keto Mini-Course: http://pxlme.me/-i717vtY or go here: http://bit.ly/2RmaFDS
Download Keto Essentials
http://bit.ly/2DH0d6o
In this video, Dr. Berg talks about liver enzymes. There are two main liver enzymes; the AST and ALT. As the liver gets damaged, these two enzymes go up. These enzymes are only one of the factors when you are evaluating.
Some Main Symptoms of Liver Damage:
• Jaundice
• Tired
• Ascites – it looks like a beer gut or a pot belly.
• Itchy Feet
• Edema
• Bloating
• Spider Veins
• Diges...
published: 09 Mar 2019
-
Lipid (Fat) Metabolism Overview, Animation
(USMLE topics) Lipid digestion and absorption; exogenous and endogenous pathways; lipolysis and lipogenesis.
Purchase a license to download a non-watermarked version of this video on AlilaMedicalMedia(dot)com
Check out our new Alila Academy - AlilaAcademy(dot)com - complete video courses with quizzes, PDFs, and downloadable images.
Voice by: Ashley Fleming
©Alila Medical Media. All rights reserved.
All images/videos by Alila Medical Media are for information purposes ONLY and are NOT intended to replace professional medical advice, diagnosis or treatment. Always seek the advice of a qualified healthcare provider with any questions you may have regarding a medical condition.
Although the term “lipid” includes several types of molecules, lipid metabolism usually refers to the breakdown...
published: 29 Jul 2020
-
lipoprotein lipase vs hepatic lipase#youtubeshorts #ytshorts #biochemistry #lipids
published: 19 Nov 2023
-
20: Enzymes & Proteins of Lipoproteins Metabolism |Lipid Metabolism| Biochemistry
#Lipoproteins
#lipoproteinmetabolism
This video describes various enzymes and protein involved in lipoprotein metabolism.
published: 02 Apr 2021
-
Medical vocabulary: What does Lipoprotein Lipase Activators mean
What does Lipoprotein Lipase Activators mean in English?
published: 20 Jan 2016
6:38
How Lipoproteins Affect Metabolism in Diabetes
There is a strong connection between type 2 diabetes and dyslipidemia. This animation describes the lipid abnormalities commonly seen in patients with type 2 di...
There is a strong connection between type 2 diabetes and dyslipidemia. This animation describes the lipid abnormalities commonly seen in patients with type 2 diabetes: elevated levels of triglycerides, raised small dense LDL levels, increased glycation and oxidation of LDLs and reduction of HDLs. These factors increase the risk of cardiovascular disease.
https://wn.com/How_Lipoproteins_Affect_Metabolism_In_Diabetes
There is a strong connection between type 2 diabetes and dyslipidemia. This animation describes the lipid abnormalities commonly seen in patients with type 2 diabetes: elevated levels of triglycerides, raised small dense LDL levels, increased glycation and oxidation of LDLs and reduction of HDLs. These factors increase the risk of cardiovascular disease.
- published: 16 Jul 2013
- views: 88788
1:03:35
Metabolism | Lipoprotein Metabolism | Chylomicrons, VLDL, IDL, LDL, & HDL
Official Ninja Nerd Website: https://ninjanerd.org
Ninja Nerds!
In this lecture Professor Zach Murphy will be discussing the metabolism of lipoproteins- Lipopr...
Official Ninja Nerd Website: https://ninjanerd.org
Ninja Nerds!
In this lecture Professor Zach Murphy will be discussing the metabolism of lipoproteins- Lipoprotein Metabolism. During this lecture we talk specifically about chylomicrons in the exogenous pathway. We also talk about VLDL, IDL and LDL and their role in the endogenous pathway. Lastly, we discuss HDL and it's role in reverse cholesterol transport as well as normal serum cholesterol levels. We hope you enjoy this lecture and be sure to support us below!
Join this channel to get access to perks:
https://www.youtube.com/channel/UC6QYFutt9cluQ3uSM963_KQ/join
APPAREL |
We are switching merchandise suppliers.
DONATE
PATREON | https://www.patreon.com/NinjaNerdScience
PAYPAL | https://www.paypal.com/paypalme/ninjanerdscience
SOCIAL MEDIA
FACEBOOK | https://www.facebook.com/NinjaNerdlectures
INSTAGRAM | https://www.instagram.com/ninjanerdlectures
TWITTER | https://twitter.com/ninjanerdsci
@NinjaNerdSci
DISCORD | https://discord.gg/3srTG4dngW
#ninjanerd #LipoproteinMetabolism #Metabolism
https://wn.com/Metabolism_|_Lipoprotein_Metabolism_|_Chylomicrons,_Vldl,_Idl,_Ldl,_Hdl
Official Ninja Nerd Website: https://ninjanerd.org
Ninja Nerds!
In this lecture Professor Zach Murphy will be discussing the metabolism of lipoproteins- Lipoprotein Metabolism. During this lecture we talk specifically about chylomicrons in the exogenous pathway. We also talk about VLDL, IDL and LDL and their role in the endogenous pathway. Lastly, we discuss HDL and it's role in reverse cholesterol transport as well as normal serum cholesterol levels. We hope you enjoy this lecture and be sure to support us below!
Join this channel to get access to perks:
https://www.youtube.com/channel/UC6QYFutt9cluQ3uSM963_KQ/join
APPAREL |
We are switching merchandise suppliers.
DONATE
PATREON | https://www.patreon.com/NinjaNerdScience
PAYPAL | https://www.paypal.com/paypalme/ninjanerdscience
SOCIAL MEDIA
FACEBOOK | https://www.facebook.com/NinjaNerdlectures
INSTAGRAM | https://www.instagram.com/ninjanerdlectures
TWITTER | https://twitter.com/ninjanerdsci
@NinjaNerdSci
DISCORD | https://discord.gg/3srTG4dngW
#ninjanerd #LipoproteinMetabolism #Metabolism
- published: 06 Jan 2018
- views: 1243787
3:27
Key enzymes in lipid transport
In this Express Video from the Biochemistry section, Daniel Griffin offers up a breakdown of the key enzymes in lipid transport, as described on p. 93 of First ...
In this Express Video from the Biochemistry section, Daniel Griffin offers up a breakdown of the key enzymes in lipid transport, as described on p. 93 of First Aid for the USMLE Step 1, 2019 edition.
https://wn.com/Key_Enzymes_In_Lipid_Transport
In this Express Video from the Biochemistry section, Daniel Griffin offers up a breakdown of the key enzymes in lipid transport, as described on p. 93 of First Aid for the USMLE Step 1, 2019 edition.
- published: 03 Aug 2019
- views: 2906
10:06
Liver and pancreatic enzymes explained | AST, ALT, GGT, ALP, Amylase & Lipase
Liver and pancreatic enzymes explained | Liver Enzymes (AST, ALT, GGT, ALP), Pancreatic Enzymes (Amylase& Lipase).
What are the liver function tests (or LFTs)?...
Liver and pancreatic enzymes explained | Liver Enzymes (AST, ALT, GGT, ALP), Pancreatic Enzymes (Amylase& Lipase).
What are the liver function tests (or LFTs)?
They are a group of blood tests that help you assess the liver function (hepatocytes).
In this medical lecture, we discuss alanine transaminase (ALT, formerly SGPT), aspartate transaminase (AST, formerly SGOT), alkaline phosphatase (ALP), and gamma-glutamyl transferase (GGT)...We also mention pancreatic enzymes such as amylase (less specific because there is also a salivary amylase) and lipase (more specific).
😍🖼Animated Mnemonics (Picmonic): https://www.picmonic.com/viphookup/medicosis/
- With Picmonic, get your life back by studying less and remembering more. Medical and Nursing students say that Picmonic is the most comprehensive and effective way to bridge learning and test prep...
Disclaimer: I use affiliate links....
►👨🏫💊Antibiotics Lectures: https://www.medicosisperfectionalis.com/products/courses/antibiotics/ ...
► Get my downloadable notes and cases at https://www.patreon.com/medicosis/ Thanks for watching…
Please subscribe :)
Don’t forget to check my recommended collection of the best medical books that I personally use https://www.amazon.com/shop/medicosisperfectionalis
*** As a small gift for my viewers, here are 2 FREE audiobooks from Audible https://amzn.to/2FQurW0 Learning has never been easier.
*** Also, try Amazon Kindle unlimited for FREE, they have some good medical books that you can read for FREE. https://amzn.to/2UceoG2
MEDICAL Sources that I use for my videos:-
► Goljan Rapid Review Pathology, https://amzn.to/2MufTPw
► Harrison’s Internal Medicine https://amzn.to/2OJiVNf
► Goldman-Cecil Medicine https://amzn.to/2N0v93u
► Davidson’s Principles and Practice of Medicine https://amzn.to/2vTmf1p
-------------------------------------------------------------------------
Many people ask me “How do you record your videos”?
Here is the answer:-
Equipment that I use:-
► Apple iPad Pro https://amzn.to/2nKCyZW
► Apple pencil https://amzn.to/2PimMCc
►Iphone holder kit: https://amzn.to/2OVV3aj
►Rode Video Mic Go: https://amzn.to/2OVF4Je
►Rode SC7 3.5mm TRS to TRRS Patch Cable: https://amzn.to/2vu2WeY
►Extension Audio Cable https://amzn.to/2nIDApo
►Rode DDC-GO DeadCat Artificial Fur Wind Shield for VideoMic GO: https://amzn.to/2OpbV8m
Disclaimer 1: The medical information contained herein is intended for educational purposes only, and are not intended for diagnosis of any illness. If you think you may be suffering from any medical condition, you should consult your physician or seek immediate medical attention.
I am NOT a licensed physician…Talk to your doctor.
Disclaimer 2: these links are affiliate links so that I get paid a percentage of the sale, to support the channel, however, the customer is not affected as they pay the same price.
Whether you’re studying for the USMLE, MCAT, shelf exam, NCLEX, COMLEX, PLEB, MCCEE, AMC_CAT, PANCE,…etc., these videos will help! Take it to the bank :)
As always…Be safe, Stay happy and Study hard!
MEDICOSIS PERFECTIONALIS
If you like my videos, please consider leaving a tip at https://www.paypal.me/perfectionalis/
► Visit my website: https://www.medicosisperfectionalis.com/
My Favorite Productivity App: https://airtable.com/invite/r/2zH40fus/
📱Save on your mobile phone bill: http://fbuy.me/q6bMj 🏦 Qbank (TrueLearn): https://truelearn.referralrock.com/l/MEDICOSIS/
https://wn.com/Liver_And_Pancreatic_Enzymes_Explained_|_Ast,_Alt,_Ggt,_Alp,_Amylase_Lipase
Liver and pancreatic enzymes explained | Liver Enzymes (AST, ALT, GGT, ALP), Pancreatic Enzymes (Amylase& Lipase).
What are the liver function tests (or LFTs)?
They are a group of blood tests that help you assess the liver function (hepatocytes).
In this medical lecture, we discuss alanine transaminase (ALT, formerly SGPT), aspartate transaminase (AST, formerly SGOT), alkaline phosphatase (ALP), and gamma-glutamyl transferase (GGT)...We also mention pancreatic enzymes such as amylase (less specific because there is also a salivary amylase) and lipase (more specific).
😍🖼Animated Mnemonics (Picmonic): https://www.picmonic.com/viphookup/medicosis/
- With Picmonic, get your life back by studying less and remembering more. Medical and Nursing students say that Picmonic is the most comprehensive and effective way to bridge learning and test prep...
Disclaimer: I use affiliate links....
►👨🏫💊Antibiotics Lectures: https://www.medicosisperfectionalis.com/products/courses/antibiotics/ ...
► Get my downloadable notes and cases at https://www.patreon.com/medicosis/ Thanks for watching…
Please subscribe :)
Don’t forget to check my recommended collection of the best medical books that I personally use https://www.amazon.com/shop/medicosisperfectionalis
*** As a small gift for my viewers, here are 2 FREE audiobooks from Audible https://amzn.to/2FQurW0 Learning has never been easier.
*** Also, try Amazon Kindle unlimited for FREE, they have some good medical books that you can read for FREE. https://amzn.to/2UceoG2
MEDICAL Sources that I use for my videos:-
► Goljan Rapid Review Pathology, https://amzn.to/2MufTPw
► Harrison’s Internal Medicine https://amzn.to/2OJiVNf
► Goldman-Cecil Medicine https://amzn.to/2N0v93u
► Davidson’s Principles and Practice of Medicine https://amzn.to/2vTmf1p
-------------------------------------------------------------------------
Many people ask me “How do you record your videos”?
Here is the answer:-
Equipment that I use:-
► Apple iPad Pro https://amzn.to/2nKCyZW
► Apple pencil https://amzn.to/2PimMCc
►Iphone holder kit: https://amzn.to/2OVV3aj
►Rode Video Mic Go: https://amzn.to/2OVF4Je
►Rode SC7 3.5mm TRS to TRRS Patch Cable: https://amzn.to/2vu2WeY
►Extension Audio Cable https://amzn.to/2nIDApo
►Rode DDC-GO DeadCat Artificial Fur Wind Shield for VideoMic GO: https://amzn.to/2OpbV8m
Disclaimer 1: The medical information contained herein is intended for educational purposes only, and are not intended for diagnosis of any illness. If you think you may be suffering from any medical condition, you should consult your physician or seek immediate medical attention.
I am NOT a licensed physician…Talk to your doctor.
Disclaimer 2: these links are affiliate links so that I get paid a percentage of the sale, to support the channel, however, the customer is not affected as they pay the same price.
Whether you’re studying for the USMLE, MCAT, shelf exam, NCLEX, COMLEX, PLEB, MCCEE, AMC_CAT, PANCE,…etc., these videos will help! Take it to the bank :)
As always…Be safe, Stay happy and Study hard!
MEDICOSIS PERFECTIONALIS
If you like my videos, please consider leaving a tip at https://www.paypal.me/perfectionalis/
► Visit my website: https://www.medicosisperfectionalis.com/
My Favorite Productivity App: https://airtable.com/invite/r/2zH40fus/
📱Save on your mobile phone bill: http://fbuy.me/q6bMj 🏦 Qbank (TrueLearn): https://truelearn.referralrock.com/l/MEDICOSIS/
- published: 22 Aug 2018
- views: 1414150
45:49
Liver, Lipid and Lipase Biochem Changes
Starting from the top... How is fat digested, absorbed, and utilised? What forms does it take? Why don't dogs have strokes and heart attacks associated with the...
Starting from the top... How is fat digested, absorbed, and utilised? What forms does it take? Why don't dogs have strokes and heart attacks associated with their high cholesterol? Why is hyperlipidaemia a problem then?
https://wn.com/Liver,_Lipid_And_Lipase_Biochem_Changes
Starting from the top... How is fat digested, absorbed, and utilised? What forms does it take? Why don't dogs have strokes and heart attacks associated with their high cholesterol? Why is hyperlipidaemia a problem then?
- published: 23 Aug 2024
- views: 55
4:10
High Liver Enzymes [ALT & AST] – What Do They Mean? – Dr.Berg
Get access to my FREE resources 👉 https://drbrg.co/3VL2pBZ
For more details on this topic, check out the full article on the website:
➡️ https://drbrg.co/3ymHx...
Get access to my FREE resources 👉 https://drbrg.co/3VL2pBZ
For more details on this topic, check out the full article on the website:
➡️ https://drbrg.co/3ymHxYl
Overview of Healthy Keto and Intermittent Fasting:
http://bit.ly/2B61L8j
http://bit.ly/2Ws2OIR
Take Dr. Berg's Free Keto Mini-Course: http://pxlme.me/-i717vtY or go here: http://bit.ly/2RmaFDS
Download Keto Essentials
http://bit.ly/2DH0d6o
In this video, Dr. Berg talks about liver enzymes. There are two main liver enzymes; the AST and ALT. As the liver gets damaged, these two enzymes go up. These enzymes are only one of the factors when you are evaluating.
Some Main Symptoms of Liver Damage:
• Jaundice
• Tired
• Ascites – it looks like a beer gut or a pot belly.
• Itchy Feet
• Edema
• Bloating
• Spider Veins
• Digestive Issues
Ratios of Enzymes:
• High AST and High ALT: Viral Hepatitis
• High AST and Normal ALT: Cirrhosis
• AST more than double than ALT: Alcoholic Liver
Ways to Repair the Liver:
1. Healthy ketogenic diet
2. Intermittent Fasting
3. Avoid refined foods
4. Avoid alcohol
5. Avoid medications
6. Consume enough vegetables
Dr. Eric Berg DC Bio:
Dr. Berg, age 59, is a chiropractor who specializes in Healthy Ketosis & Intermittent Fasting. He is the author of the best-selling book The Healthy Keto Plan and is the Director of Dr. Berg Nutritionals. He no longer practices but focuses on health education through social media.
Follow Me on Social Media:
Facebook: https://bit.ly/FB-DrBerg
Instagram: https://bit.ly/IG-DrBerg
Listen to my Podcast: https://bit.ly/drberg-podcast
TikTok: https://bit.ly/TikTok-DrBerg
Disclaimer:
Dr. Eric Berg received his Doctor of Chiropractic degree from Palmer College of Chiropractic in 1988. His use of “doctor” or “Dr.” in relation to himself solely refers to that degree. Dr. Berg is a licensed chiropractor in Virginia, California, and Louisiana, but he no longer practices chiropractic in any state and does not see patients, so he can focus on educating people as a full-time activity, yet he maintains an active license. This video is for general informational purposes only. It should not be used to self-diagnose, and it is not a substitute for a medical exam, cure, treatment, diagnosis, prescription, or recommendation. It does not create a doctor-patient relationship between Dr. Berg and you. You should not make any change in your health regimen or diet before first consulting a physician and obtaining a medical exam, diagnosis, and recommendation. Always seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition.
#liver #healthyliver #fattyliver #keto #ketodiet #ketogenicdiet #jaundice #ketosis #ketomadeeasy
#keto #ketodiet #weightloss #ketosis
https://wn.com/High_Liver_Enzymes_Alt_Ast_–_What_Do_They_Mean_–_Dr.Berg
Get access to my FREE resources 👉 https://drbrg.co/3VL2pBZ
For more details on this topic, check out the full article on the website:
➡️ https://drbrg.co/3ymHxYl
Overview of Healthy Keto and Intermittent Fasting:
http://bit.ly/2B61L8j
http://bit.ly/2Ws2OIR
Take Dr. Berg's Free Keto Mini-Course: http://pxlme.me/-i717vtY or go here: http://bit.ly/2RmaFDS
Download Keto Essentials
http://bit.ly/2DH0d6o
In this video, Dr. Berg talks about liver enzymes. There are two main liver enzymes; the AST and ALT. As the liver gets damaged, these two enzymes go up. These enzymes are only one of the factors when you are evaluating.
Some Main Symptoms of Liver Damage:
• Jaundice
• Tired
• Ascites – it looks like a beer gut or a pot belly.
• Itchy Feet
• Edema
• Bloating
• Spider Veins
• Digestive Issues
Ratios of Enzymes:
• High AST and High ALT: Viral Hepatitis
• High AST and Normal ALT: Cirrhosis
• AST more than double than ALT: Alcoholic Liver
Ways to Repair the Liver:
1. Healthy ketogenic diet
2. Intermittent Fasting
3. Avoid refined foods
4. Avoid alcohol
5. Avoid medications
6. Consume enough vegetables
Dr. Eric Berg DC Bio:
Dr. Berg, age 59, is a chiropractor who specializes in Healthy Ketosis & Intermittent Fasting. He is the author of the best-selling book The Healthy Keto Plan and is the Director of Dr. Berg Nutritionals. He no longer practices but focuses on health education through social media.
Follow Me on Social Media:
Facebook: https://bit.ly/FB-DrBerg
Instagram: https://bit.ly/IG-DrBerg
Listen to my Podcast: https://bit.ly/drberg-podcast
TikTok: https://bit.ly/TikTok-DrBerg
Disclaimer:
Dr. Eric Berg received his Doctor of Chiropractic degree from Palmer College of Chiropractic in 1988. His use of “doctor” or “Dr.” in relation to himself solely refers to that degree. Dr. Berg is a licensed chiropractor in Virginia, California, and Louisiana, but he no longer practices chiropractic in any state and does not see patients, so he can focus on educating people as a full-time activity, yet he maintains an active license. This video is for general informational purposes only. It should not be used to self-diagnose, and it is not a substitute for a medical exam, cure, treatment, diagnosis, prescription, or recommendation. It does not create a doctor-patient relationship between Dr. Berg and you. You should not make any change in your health regimen or diet before first consulting a physician and obtaining a medical exam, diagnosis, and recommendation. Always seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition.
#liver #healthyliver #fattyliver #keto #ketodiet #ketogenicdiet #jaundice #ketosis #ketomadeeasy
#keto #ketodiet #weightloss #ketosis
- published: 09 Mar 2019
- views: 427708
4:16
Lipid (Fat) Metabolism Overview, Animation
(USMLE topics) Lipid digestion and absorption; exogenous and endogenous pathways; lipolysis and lipogenesis.
Purchase a license to download a non-watermarked ...
(USMLE topics) Lipid digestion and absorption; exogenous and endogenous pathways; lipolysis and lipogenesis.
Purchase a license to download a non-watermarked version of this video on AlilaMedicalMedia(dot)com
Check out our new Alila Academy - AlilaAcademy(dot)com - complete video courses with quizzes, PDFs, and downloadable images.
Voice by: Ashley Fleming
©Alila Medical Media. All rights reserved.
All images/videos by Alila Medical Media are for information purposes ONLY and are NOT intended to replace professional medical advice, diagnosis or treatment. Always seek the advice of a qualified healthcare provider with any questions you may have regarding a medical condition.
Although the term “lipid” includes several types of molecules, lipid metabolism usually refers to the breakdown and synthesis of fats. Fats are triglycerides, they are esters of glycerol and three fatty acids. Fats can come from the diet, from stores in adipose tissue, or can be synthesized from excess dietary carbohydrates in the liver.
Dietary fats are digested mainly in the small intestine, by the action of bile salts and pancreatic lipase. Bile salts emulsify fats. They act as a detergent, breaking large globules of fat into smaller micelles, making them more accessible to lipase. Pancreatic lipase then converts triglycerides into monoglycerides, free fatty acids, and glycerol. These products move into the cells of intestinal epithelium - the enterocytes, inside which they re-combine again to form triglycerides. Triglycerides are packaged along with cholesterol into large lipoprotein particles called chylomicrons. Lipoproteins enable transport of water-insoluble fats within aqueous environments. Chylomicrons leave the enterocytes, enter lymphatic capillaries, and eventually pass into the bloodstream, delivering fats to tissues. The walls of blood capillaries have a surface enzyme called lipoprotein lipase. This enzyme hydrolyzes triglycerides into fatty acids and glycerol, enabling them to pass through the capillary wall into tissues, where they are oxidized for energy, or re-esterized for storage.
Fats that are synthesized endogenously in the liver are packed into another type of lipoprotein, the VLDL, to be transported to tissues, where triglycerides are extracted in the same way.
When required, fat stores in adipose tissue are mobilized for energy production, by the action of hormone-sensitive lipase, which responds to hormones such as epinephrine.
Lipid metabolism pathways are closely connected to those of carbohydrate metabolism. Glycerol is converted to a glycolysis intermediate, while fatty acids undergo beta-oxidation to generate acetyl-CoA. Each round of beta-oxidation removes 2 carbons from the fatty acid chain, releasing one acetyl-CoA, which can then be oxidized in the citric acid cycle. Beta-oxidation also produces several high-energy molecules which are fed directly to the electron transport system. Fats yield more energy per unit mass than carbohydrates.
When acetyl-CoA is produced in excess, it is diverted to create ketone bodies. During glucose starvation, ketone bodies are an important source of fuel, especially for the brain. However, ketone bodies are acidic, and when produced in excess, can overwhelm the buffering capacity of blood plasma, resulting in metabolic acidosis, which can lead to coma and death. Ketoacidosis is a serious complication of diabetes, in which cells must oxidize fats for fuel as they cannot utilize glucose. Extreme diets that are excessively low in carbohydrates and high in fat may also result in ketoacidosis.
On the other hand, diets that are high in carbohydrates generate excess acetyl-CoA that can be converted into fatty acids. Synthesis of fatty acids from acetyl-CoA is stimulated by citrate, a marker of energy abundance, and inhibited by excess of fatty acids. Fatty acids can be converted into triglycerides, for storage or synthesis of other lipids, by combining with glycerol derived from a glycolysis intermediate.
https://wn.com/Lipid_(Fat)_Metabolism_Overview,_Animation
(USMLE topics) Lipid digestion and absorption; exogenous and endogenous pathways; lipolysis and lipogenesis.
Purchase a license to download a non-watermarked version of this video on AlilaMedicalMedia(dot)com
Check out our new Alila Academy - AlilaAcademy(dot)com - complete video courses with quizzes, PDFs, and downloadable images.
Voice by: Ashley Fleming
©Alila Medical Media. All rights reserved.
All images/videos by Alila Medical Media are for information purposes ONLY and are NOT intended to replace professional medical advice, diagnosis or treatment. Always seek the advice of a qualified healthcare provider with any questions you may have regarding a medical condition.
Although the term “lipid” includes several types of molecules, lipid metabolism usually refers to the breakdown and synthesis of fats. Fats are triglycerides, they are esters of glycerol and three fatty acids. Fats can come from the diet, from stores in adipose tissue, or can be synthesized from excess dietary carbohydrates in the liver.
Dietary fats are digested mainly in the small intestine, by the action of bile salts and pancreatic lipase. Bile salts emulsify fats. They act as a detergent, breaking large globules of fat into smaller micelles, making them more accessible to lipase. Pancreatic lipase then converts triglycerides into monoglycerides, free fatty acids, and glycerol. These products move into the cells of intestinal epithelium - the enterocytes, inside which they re-combine again to form triglycerides. Triglycerides are packaged along with cholesterol into large lipoprotein particles called chylomicrons. Lipoproteins enable transport of water-insoluble fats within aqueous environments. Chylomicrons leave the enterocytes, enter lymphatic capillaries, and eventually pass into the bloodstream, delivering fats to tissues. The walls of blood capillaries have a surface enzyme called lipoprotein lipase. This enzyme hydrolyzes triglycerides into fatty acids and glycerol, enabling them to pass through the capillary wall into tissues, where they are oxidized for energy, or re-esterized for storage.
Fats that are synthesized endogenously in the liver are packed into another type of lipoprotein, the VLDL, to be transported to tissues, where triglycerides are extracted in the same way.
When required, fat stores in adipose tissue are mobilized for energy production, by the action of hormone-sensitive lipase, which responds to hormones such as epinephrine.
Lipid metabolism pathways are closely connected to those of carbohydrate metabolism. Glycerol is converted to a glycolysis intermediate, while fatty acids undergo beta-oxidation to generate acetyl-CoA. Each round of beta-oxidation removes 2 carbons from the fatty acid chain, releasing one acetyl-CoA, which can then be oxidized in the citric acid cycle. Beta-oxidation also produces several high-energy molecules which are fed directly to the electron transport system. Fats yield more energy per unit mass than carbohydrates.
When acetyl-CoA is produced in excess, it is diverted to create ketone bodies. During glucose starvation, ketone bodies are an important source of fuel, especially for the brain. However, ketone bodies are acidic, and when produced in excess, can overwhelm the buffering capacity of blood plasma, resulting in metabolic acidosis, which can lead to coma and death. Ketoacidosis is a serious complication of diabetes, in which cells must oxidize fats for fuel as they cannot utilize glucose. Extreme diets that are excessively low in carbohydrates and high in fat may also result in ketoacidosis.
On the other hand, diets that are high in carbohydrates generate excess acetyl-CoA that can be converted into fatty acids. Synthesis of fatty acids from acetyl-CoA is stimulated by citrate, a marker of energy abundance, and inhibited by excess of fatty acids. Fatty acids can be converted into triglycerides, for storage or synthesis of other lipids, by combining with glycerol derived from a glycolysis intermediate.
- published: 29 Jul 2020
- views: 898910
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20: Enzymes & Proteins of Lipoproteins Metabolism |Lipid Metabolism| Biochemistry
#Lipoproteins
#lipoproteinmetabolism
This video describes various enzymes and protein involved in lipoprotein metabolism.
#Lipoproteins
#lipoproteinmetabolism
This video describes various enzymes and protein involved in lipoprotein metabolism.
https://wn.com/20_Enzymes_Proteins_Of_Lipoproteins_Metabolism_|Lipid_Metabolism|_Biochemistry
#Lipoproteins
#lipoproteinmetabolism
This video describes various enzymes and protein involved in lipoprotein metabolism.
- published: 02 Apr 2021
- views: 10523