- published: 05 Oct 2009
- views: 20670
Carol W. Greider
Carolyn Widney "Carol" Greider (born April 15, 1961) is an American molecular biologist. She is a Bloomberg Distinguished Professor, Daniel Nathans Professor and Director of Molecular Biology and Genetics at Johns Hopkins University. She discovered the enzyme telomerase in 1984, when she was a graduate student of Elizabeth Blackburn at the University of California, Berkeley. Greider pioneered research on the structure of telomeres, the ends of the chromosomes. She was awarded the 2009 Nobel Prize for Physiology or Medicine, along with Blackburn and Jack W. Szostak, for their discovery that telomeres are protected from progressive shortening by the enzyme telomerase.
Early life and education
Greider was born in San Diego, California. Her father, Kenneth Greider, was a physics professor. Her family moved from San Diego to Davis, California, where she spent many of her early years and graduated from Davis Senior High School in 1979. She graduated from the College of Creative Studies at the University of California, Santa Barbara, with a B.A. in biology in 1983. During this time she also studied at the University of Göttingen and made significant discoveries there.
This page contains text from Wikipedia, the Free Encyclopedia - https://wn.com/Carol_W._Greider
Podcasts:
-
Interview with Carol Greider on winning the 2009 Nobel Prize in Physiology or Medicine
October 5, 2009- Carol Greider, Ph.D., 48, one of the worlds pioneering researchers on the structure of chromosome ends known as telomeres, today was awarded the 2009 Nobel Prize in Physiology or Medicine by the Royal Swedish Academy of Sciences. The Academy recognized her for her 1984 discovery of telomerase (ta-LAW-mer-ace), an enzyme that maintains the length and integrity of chromosome ends and is critical for the health and survival of all living cells and organisms. http://www.hopkinsmedicine.org/
published: 05 Oct 2009 -
Interview with Elizabeth H. Blackburn, Ph.D., and Carol Greider, Ph.D.
Annual Meeting 2010 Episode __: Recipients of the 2009 Nobel Prize in Physiology or Medicine, Elizabeth H. Blackburn, Ph.D., and Carol Greider, Ph.D., talk about their discovery of how chromosomes are protected by telomeres and the enzyme telomerase and the honor of receiving the Nobel Prize.
published: 19 Apr 2010 -
Big Think Interview With Carol Greider | Big Think
Big Think Interview With Carol Greider New videos DAILY: https://bigth.ink/youtube Join Big Think Edge for exclusive videos: https://bigth.ink/Edge ---------------------------------------------------------------------------------- A conversation with the Johns Hopkins University molecular biologist and co-winner of the 2009 Nobel Prize in Medicine. ---------------------------------------------------------------------------------- Carol W. Greider: Carol W. Greider is the Daniel Nathans Professor & Director of Molecular Biology & Genetics at Johns Hopkins University. Her research on telomerase (an enzyme she helped discover) and telomere function won her a 2009 Nobel Prize in Medicine. Prior to joining the Johns Hopkins faculty, she obtained a Ph.D. in Molecular Biology from the Universi...
published: 24 Apr 2012 -
Telomeres - Research by Carol W. Greider
Carol W. Greider - The pioneered research on the structure of telomeres, the ends of the chromosomes. She was awarded the 2009 Nobel Prize for Physiology or Medicine, along with Blackburn and Jack W. Szostak, for their discovery that telomeres are protected from progressive shortening by the enzyme telomerase. Note: Carol W. Greider is an independent researcher and not associated with Jeunesse Global products. This video is only for educational purposes. This video is also not for any youtube advertisement monetization. More info on telomere supplementary product: Contact Danyelle via Facebook: https://m.me/danyelle.tcl, or Contact Danyelle via Telegram @DanyelleTan
published: 14 Dec 2020 -
One Geneticist, Two X Chromosomes | Carol W. Greider | Big Think
One Geneticist, Two X Chromosomes New videos DAILY: https://bigth.ink/youtube Join Big Think Edge for exclusive videos: https://bigth.ink/Edge ---------------------------------------------------------------------------------- The Nobel Prize-winning molecular biologist weighs in on gender discrimination in science and advises young women entering the profession. ---------------------------------------------------------------------------------- Carol W. Greider: Carol W. Greider is the Daniel Nathans Professor & Director of Molecular Biology & Genetics at Johns Hopkins University. Her research on telomerase (an enzyme she helped discover) and telomere function won her a 2009 Nobel Prize in Medicine. Prior to joining the Johns Hopkins faculty, she obtained a Ph.D. in Molecular Biology fro...
published: 24 Apr 2012 -
Carol Greider - UMD Bioscience Day 2016 Young Lecture
University of Maryland Bioscience Day 2016 DR. ERIK B. AND MRS. JOYCE D.C. YOUNG LECTURE "Telomerase and the regulation of telomere length equilibrium" by CAROL GREIDER 2009 Nobel Laureate in Physiology or Medicine Daniel Nathans Professor and Director, Department of Molecular Biology & Genetics, Johns Hopkins University School of Medicine Bloomberg Distinguished Professor, Department of Biology, Johns Hopkins University Abstract Telomeres are conserved structures that protect chromosome ends in eukaryotes. Telomeres shorten with cell division, and this shortening is counterbalanced by telomerase, which adds telomere repeats onto chromosome ends. The disruption of telomere length maintenance is associated with both cancer and age-related disease. Inappropriate elongation of telomeres ca...
published: 07 Nov 2016 -
Nobel Laureate Professor Carol W. Greider
The 2009 American Nobel Laureates were honored at a luncheon at the American Ambassador's Residence in Stockholm on December 9. All eight were asked to answer the following question: "What advice would you give to your 20-year-old self on making a real difference in the world, knowing what you know today?" In this clip the 2009 Nobel Laureate in Physiology or Medicine, Professor Carol W. Greider, offers her thoughts on the question. Professor Greider works at the John Hopkins University School of Medicine in Baltimore.
published: 09 Dec 2009 -
Carol W. Greider Top # 5 Facts
Carol W. Greider Top # 5 Facts
published: 02 Nov 2015 -
Carol Greider, Ph.D., Nobel Opening Remarks
Carol Greider, a professor in the Johns Hopkins University School of Medicine and the Daniel Nathans Director of Molecular Biology and Genetics in the schools Institute for Basic Biomedical Sciences, has been awarded a share of this years Nobel Prize in Physiology or Medicine. The Royal Swedish Academy of Sciences recognized Greider for her 1984 discovery of telomerase, an enzyme that maintains the length and integrity of chromosome ends and is critical for the health and survival of all living cells and organisms. The discovery important and of itself for increasing our understanding of how cells work also has turned out to have far-reaching implications for the investigation of cancer and certain aging-related diseases. She shares the Nobel with Eizabeth Blackburn, a profes...
published: 05 Oct 2009 -
Carol Greider, Ph.D. - Discovering Telomerase and Winning the Nobel Prize
This prominent molecular biologist at Johns Hopkins won the Nobel Prize in 2009 for her discovery of the key chromosomal enzyme, telomerase. Learn about this pioneering researcher's challenging road to her breakthrough discovery.
published: 03 Oct 2017
developed with YouTube
2:35
Interview with Carol Greider on winning the 2009 Nobel Prize in Physiology or Medicine
- Order: Reorder
- Duration: 2:35
- Uploaded Date: 05 Oct 2009
- views: 20670
October 5, 2009- Carol Greider, Ph.D., 48, one of the worlds pioneering researchers on the structure of chromosome ends known as telomeres, today was awarded th...
October 5, 2009- Carol Greider, Ph.D., 48, one of the worlds pioneering researchers on the structure of chromosome ends known as telomeres, today was awarded the 2009 Nobel Prize in Physiology or Medicine by the Royal Swedish Academy of Sciences. The Academy recognized her for her 1984 discovery of telomerase (ta-LAW-mer-ace), an enzyme that maintains the length and integrity of chromosome ends and is critical for the health and survival of all living cells and organisms.
http://www.hopkinsmedicine.org/
https://wn.com/Interview_With_Carol_Greider_On_Winning_The_2009_Nobel_Prize_In_Physiology_Or_Medicine
October 5, 2009- Carol Greider, Ph.D., 48, one of the worlds pioneering researchers on the structure of chromosome ends known as telomeres, today was awarded the 2009 Nobel Prize in Physiology or Medicine by the Royal Swedish Academy of Sciences. The Academy recognized her for her 1984 discovery of telomerase (ta-LAW-mer-ace), an enzyme that maintains the length and integrity of chromosome ends and is critical for the health and survival of all living cells and organisms.
http://www.hopkinsmedicine.org/
10:50
Interview with Elizabeth H. Blackburn, Ph.D., and Carol Greider, Ph.D.
- Order: Reorder
- Duration: 10:50
- Uploaded Date: 19 Apr 2010
- views: 5275
Annual Meeting 2010 Episode __: Recipients of the 2009 Nobel Prize in Physiology or Medicine, Elizabeth H. Blackburn, Ph.D., and Carol Greider, Ph.D., talk abou...
Annual Meeting 2010 Episode __: Recipients of the 2009 Nobel Prize in Physiology or Medicine, Elizabeth H. Blackburn, Ph.D., and Carol Greider, Ph.D., talk about their discovery of how chromosomes are protected by telomeres and the enzyme telomerase and the honor of receiving the Nobel Prize.
https://wn.com/Interview_With_Elizabeth_H._Blackburn,_Ph.D.,_And_Carol_Greider,_Ph.D.
Annual Meeting 2010 Episode __: Recipients of the 2009 Nobel Prize in Physiology or Medicine, Elizabeth H. Blackburn, Ph.D., and Carol Greider, Ph.D., talk about their discovery of how chromosomes are protected by telomeres and the enzyme telomerase and the honor of receiving the Nobel Prize.
- published: 19 Apr 2010
- views: 5275
25:00
Big Think Interview With Carol Greider | Big Think
- Order: Reorder
- Duration: 25:00
- Uploaded Date: 24 Apr 2012
- views: 1660
Big Think Interview With Carol Greider
New videos DAILY: https://bigth.ink/youtube
Join Big Think Edge for exclusive videos: https://bigth.ink/Edge
------------...
Big Think Interview With Carol Greider
New videos DAILY: https://bigth.ink/youtube
Join Big Think Edge for exclusive videos: https://bigth.ink/Edge
----------------------------------------------------------------------------------
A conversation with the Johns Hopkins University molecular biologist and co-winner of the 2009 Nobel Prize in Medicine.
----------------------------------------------------------------------------------
Carol W. Greider:
Carol W. Greider is the Daniel Nathans Professor & Director of Molecular Biology & Genetics at Johns Hopkins University. Her research on telomerase (an enzyme she helped discover) and telomere function won her a 2009 Nobel Prize in Medicine. Prior to joining the Johns Hopkins faculty, she obtained a Ph.D. in Molecular Biology from the University of California, Berkeley, in 1997, and was a faculty member at the Cold Spring Harbor Laboratory. She is a member of the National Academy of Sciences and a recipient of the 1998 Gairdner Foundation International Award.
----------------------------------------------------------------------------------
TRANSCRIPT:
Question: Have you encountered any gender-specific obstacles as a scientist?
Carol Greider: I think that that's a very complicated kind of question, because although I really feel like I never had a particular obstacle that I had to overcome as a female scientist—I never felt that I was singled out or had anything done against me—I do see that when one looks at where women are in science that there is a very large discrepancy, and that there does seem to be an inability for women to get to higher echelons in the scientific hierarchy or in academia. So I think that although I didn't feel like I had anything done personally to me, I think that there may be more subtle social interactions at play in the scientific world that does have a little bit of a negative effect on women advancing in their careers.
Question: What can be done to remove these obstacles?
Carol Greider: I think that as more women get into higher levels of science, and as it's very clear to younger women coming into the field that yes, it is possible to get to the higher ranks, that will help. And also I think that the way that women run meetings, and when the power structure is such that you have a larger representation of women at higher levels, that the conversation may change somewhat. And so that could also be helpful moving forward.
Question: What is your advice to female scientists starting out today?
Carol Greider: Just follow what you're excited about. I would say the same thing to female scientists as to male scientists, to all young people, really: the fun thing is to be able to do something that excites you. A lot of times what we do is a lot of hard work, but hard work is actually okay if you really are engaged in it. And so that really, I think, is the main thing, is find something that you're passionate about and be able to follow that.
Question: How did it feel to win the Nobel Prize?
Carol Greider: That was very exciting. It was a tremendous honor to get a phone call from Stockholm and to share it with Elizabeth Blackburn, who I've worked with for many years, as well as Jack Szostak. So I was very excited, and I was very happy that I got to share the day with my children. I was able to wake them up at five o'clock in the morning after I got this phone call and to have them there with me to share and to celebrate.
Question: What role did you and your co-winners each play in the prizewinning research?
Carol Greider: Yeah, Liz Blackburn and Jack Szostak had a collaboration in the early 1980s where they were interested in trying to understand the function of telomeres. And they had a collaboration which was a cross-country collaboration with one in Berkeley and the other one in Boston. And they would call each other up on the phone and explain experiments and send materials back and forth. And that collaboration resulted in this idea that there may be some way that the cells have of maintaining their chromosome ends. It was known that chromosome ends would shorten every time a cell divided, and in doing a collaboration to try and understand the functional components that make up the telomeres they proposed that there may be an enzyme that lengthens telomeres. And so then when I went to graduate school at U.C. Berkeley and I met Liz Blackburn, that was the project—after I had worked on a smaller project in her lab—that was the project that I thought was the most exciting to follow up on and find out, is there really going to be this hypothesized enzyme which can lengthen telomeres? So that's when I started to work with Liz Blackburn, and it was together in her laboratory that we discovered the enzyme telomerase.
Read the full transcript at https://bigthink.com/videos/big-think-interview-with-carol-greider/
https://wn.com/Big_Think_Interview_With_Carol_Greider_|_Big_Think
Big Think Interview With Carol Greider
New videos DAILY: https://bigth.ink/youtube
Join Big Think Edge for exclusive videos: https://bigth.ink/Edge
----------------------------------------------------------------------------------
A conversation with the Johns Hopkins University molecular biologist and co-winner of the 2009 Nobel Prize in Medicine.
----------------------------------------------------------------------------------
Carol W. Greider:
Carol W. Greider is the Daniel Nathans Professor & Director of Molecular Biology & Genetics at Johns Hopkins University. Her research on telomerase (an enzyme she helped discover) and telomere function won her a 2009 Nobel Prize in Medicine. Prior to joining the Johns Hopkins faculty, she obtained a Ph.D. in Molecular Biology from the University of California, Berkeley, in 1997, and was a faculty member at the Cold Spring Harbor Laboratory. She is a member of the National Academy of Sciences and a recipient of the 1998 Gairdner Foundation International Award.
----------------------------------------------------------------------------------
TRANSCRIPT:
Question: Have you encountered any gender-specific obstacles as a scientist?
Carol Greider: I think that that's a very complicated kind of question, because although I really feel like I never had a particular obstacle that I had to overcome as a female scientist—I never felt that I was singled out or had anything done against me—I do see that when one looks at where women are in science that there is a very large discrepancy, and that there does seem to be an inability for women to get to higher echelons in the scientific hierarchy or in academia. So I think that although I didn't feel like I had anything done personally to me, I think that there may be more subtle social interactions at play in the scientific world that does have a little bit of a negative effect on women advancing in their careers.
Question: What can be done to remove these obstacles?
Carol Greider: I think that as more women get into higher levels of science, and as it's very clear to younger women coming into the field that yes, it is possible to get to the higher ranks, that will help. And also I think that the way that women run meetings, and when the power structure is such that you have a larger representation of women at higher levels, that the conversation may change somewhat. And so that could also be helpful moving forward.
Question: What is your advice to female scientists starting out today?
Carol Greider: Just follow what you're excited about. I would say the same thing to female scientists as to male scientists, to all young people, really: the fun thing is to be able to do something that excites you. A lot of times what we do is a lot of hard work, but hard work is actually okay if you really are engaged in it. And so that really, I think, is the main thing, is find something that you're passionate about and be able to follow that.
Question: How did it feel to win the Nobel Prize?
Carol Greider: That was very exciting. It was a tremendous honor to get a phone call from Stockholm and to share it with Elizabeth Blackburn, who I've worked with for many years, as well as Jack Szostak. So I was very excited, and I was very happy that I got to share the day with my children. I was able to wake them up at five o'clock in the morning after I got this phone call and to have them there with me to share and to celebrate.
Question: What role did you and your co-winners each play in the prizewinning research?
Carol Greider: Yeah, Liz Blackburn and Jack Szostak had a collaboration in the early 1980s where they were interested in trying to understand the function of telomeres. And they had a collaboration which was a cross-country collaboration with one in Berkeley and the other one in Boston. And they would call each other up on the phone and explain experiments and send materials back and forth. And that collaboration resulted in this idea that there may be some way that the cells have of maintaining their chromosome ends. It was known that chromosome ends would shorten every time a cell divided, and in doing a collaboration to try and understand the functional components that make up the telomeres they proposed that there may be an enzyme that lengthens telomeres. And so then when I went to graduate school at U.C. Berkeley and I met Liz Blackburn, that was the project—after I had worked on a smaller project in her lab—that was the project that I thought was the most exciting to follow up on and find out, is there really going to be this hypothesized enzyme which can lengthen telomeres? So that's when I started to work with Liz Blackburn, and it was together in her laboratory that we discovered the enzyme telomerase.
Read the full transcript at https://bigthink.com/videos/big-think-interview-with-carol-greider/
- published: 24 Apr 2012
- views: 1660
2:36
Telomeres - Research by Carol W. Greider
- Order: Reorder
- Duration: 2:36
- Uploaded Date: 14 Dec 2020
- views: 20
Carol W. Greider - The pioneered research on the structure of telomeres, the ends of the chromosomes.
She was awarded the 2009 Nobel Prize for Physiology or M...
Carol W. Greider - The pioneered research on the structure of telomeres, the ends of the chromosomes.
She was awarded the 2009 Nobel Prize for Physiology or Medicine, along with Blackburn and Jack W. Szostak, for their discovery that telomeres are protected from progressive shortening by the enzyme telomerase.
Note:
Carol W. Greider is an independent researcher and not associated with Jeunesse Global products. This video is only for educational purposes. This video is also not for any youtube advertisement monetization.
More info on telomere supplementary product:
Contact Danyelle via Facebook: https://m.me/danyelle.tcl, or
Contact Danyelle via Telegram @DanyelleTan
https://wn.com/Telomeres_Research_By_Carol_W._Greider
Carol W. Greider - The pioneered research on the structure of telomeres, the ends of the chromosomes.
She was awarded the 2009 Nobel Prize for Physiology or Medicine, along with Blackburn and Jack W. Szostak, for their discovery that telomeres are protected from progressive shortening by the enzyme telomerase.
Note:
Carol W. Greider is an independent researcher and not associated with Jeunesse Global products. This video is only for educational purposes. This video is also not for any youtube advertisement monetization.
More info on telomere supplementary product:
Contact Danyelle via Facebook: https://m.me/danyelle.tcl, or
Contact Danyelle via Telegram @DanyelleTan
- published: 14 Dec 2020
- views: 20
2:20
One Geneticist, Two X Chromosomes | Carol W. Greider | Big Think
- Order: Reorder
- Duration: 2:20
- Uploaded Date: 24 Apr 2012
- views: 518
One Geneticist, Two X Chromosomes
New videos DAILY: https://bigth.ink/youtube
Join Big Think Edge for exclusive videos: https://bigth.ink/Edge
-----------------...
One Geneticist, Two X Chromosomes
New videos DAILY: https://bigth.ink/youtube
Join Big Think Edge for exclusive videos: https://bigth.ink/Edge
----------------------------------------------------------------------------------
The Nobel Prize-winning molecular biologist weighs in on gender discrimination in science and advises young women entering the profession.
----------------------------------------------------------------------------------
Carol W. Greider:
Carol W. Greider is the Daniel Nathans Professor & Director of Molecular Biology & Genetics at Johns Hopkins University. Her research on telomerase (an enzyme she helped discover) and telomere function won her a 2009 Nobel Prize in Medicine. Prior to joining the Johns Hopkins faculty, she obtained a Ph.D. in Molecular Biology from the University of California, Berkeley, in 1997, and was a faculty member at the Cold Spring Harbor Laboratory. She is a member of the National Academy of Sciences and a recipient of the 1998 Gairdner Foundation International Award.
----------------------------------------------------------------------------------
TRANSCRIPT:
Question: Have you encountered any gender-specific obstacles as a scientist?
Carol Greider: I think that that's a very complicated kind of question, because although I really feel like I never had a particular obstacle that I had to overcome as a female scientist—I never felt that I was singled out or had anything done against me—I do see that when one looks at where women are in science that there is a very large discrepancy, and that there does seem to be an inability for women to get to higher echelons in the scientific hierarchy or in academia. So I think that although I didn't feel like I had anything done personally to me, I think that there may be more subtle social interactions at play in the scientific world that does have a little bit of a negative effect on women advancing in their careers.
Question: What can be done to remove these obstacles?
Carol Greider: I think that as more women get into higher levels of science, and as it's very clear to younger women coming into the field that yes, it is possible to get to the higher ranks, that will help. And also I think that the way that women run meetings, and when the power structure is such that you have a larger representation of women at higher levels, that the conversation may change somewhat. And so that could also be helpful moving forward.
Question: What is your advice to female scientists starting out today?
Carol Greider: Just follow what you're excited about. I would say the same thing to female scientists as to male scientists, to all young people, really: the fun thing is to be able to do something that excites you. A lot of times what we do is a lot of hard work, but hard work is actually okay if you really are engaged in it. And so that really, I think, is the main thing, is find something that you're passionate about and be able to follow that.
Recorded November 10th, 2009
Interviewed by Austin Allen
https://wn.com/One_Geneticist,_Two_X_Chromosomes_|_Carol_W._Greider_|_Big_Think
One Geneticist, Two X Chromosomes
New videos DAILY: https://bigth.ink/youtube
Join Big Think Edge for exclusive videos: https://bigth.ink/Edge
----------------------------------------------------------------------------------
The Nobel Prize-winning molecular biologist weighs in on gender discrimination in science and advises young women entering the profession.
----------------------------------------------------------------------------------
Carol W. Greider:
Carol W. Greider is the Daniel Nathans Professor & Director of Molecular Biology & Genetics at Johns Hopkins University. Her research on telomerase (an enzyme she helped discover) and telomere function won her a 2009 Nobel Prize in Medicine. Prior to joining the Johns Hopkins faculty, she obtained a Ph.D. in Molecular Biology from the University of California, Berkeley, in 1997, and was a faculty member at the Cold Spring Harbor Laboratory. She is a member of the National Academy of Sciences and a recipient of the 1998 Gairdner Foundation International Award.
----------------------------------------------------------------------------------
TRANSCRIPT:
Question: Have you encountered any gender-specific obstacles as a scientist?
Carol Greider: I think that that's a very complicated kind of question, because although I really feel like I never had a particular obstacle that I had to overcome as a female scientist—I never felt that I was singled out or had anything done against me—I do see that when one looks at where women are in science that there is a very large discrepancy, and that there does seem to be an inability for women to get to higher echelons in the scientific hierarchy or in academia. So I think that although I didn't feel like I had anything done personally to me, I think that there may be more subtle social interactions at play in the scientific world that does have a little bit of a negative effect on women advancing in their careers.
Question: What can be done to remove these obstacles?
Carol Greider: I think that as more women get into higher levels of science, and as it's very clear to younger women coming into the field that yes, it is possible to get to the higher ranks, that will help. And also I think that the way that women run meetings, and when the power structure is such that you have a larger representation of women at higher levels, that the conversation may change somewhat. And so that could also be helpful moving forward.
Question: What is your advice to female scientists starting out today?
Carol Greider: Just follow what you're excited about. I would say the same thing to female scientists as to male scientists, to all young people, really: the fun thing is to be able to do something that excites you. A lot of times what we do is a lot of hard work, but hard work is actually okay if you really are engaged in it. And so that really, I think, is the main thing, is find something that you're passionate about and be able to follow that.
Recorded November 10th, 2009
Interviewed by Austin Allen
- published: 24 Apr 2012
- views: 518
1:03:47
Carol Greider - UMD Bioscience Day 2016 Young Lecture
- Order: Reorder
- Duration: 1:03:47
- Uploaded Date: 07 Nov 2016
- views: 339
University of Maryland Bioscience Day 2016
DR. ERIK B. AND MRS. JOYCE D.C. YOUNG LECTURE
"Telomerase and the regulation of telomere length equilibrium"
by
CAR...
University of Maryland Bioscience Day 2016
DR. ERIK B. AND MRS. JOYCE D.C. YOUNG LECTURE
"Telomerase and the regulation of telomere length equilibrium"
by
CAROL GREIDER
2009 Nobel Laureate in Physiology or Medicine
Daniel Nathans Professor and Director, Department of Molecular Biology & Genetics, Johns Hopkins University School of Medicine
Bloomberg Distinguished Professor, Department of Biology, Johns Hopkins University
Abstract
Telomeres are conserved structures that protect chromosome ends in eukaryotes. Telomeres shorten with cell division, and this shortening is counterbalanced by telomerase, which adds telomere repeats onto chromosome ends. The disruption of telomere length maintenance is associated with both cancer and age-related disease. Inappropriate elongation of telomeres can allow the continued growth of cancer cells. On the other hand, insufficient telomere maintenance causes a spectrum of disease in humans including bone marrow failure, pulmonary fibrosis and immune senescence, collectively known as telomere syndromes. The mechanism that establishes and maintains telomere length equilibrium is not fully understood. This equilibrium involves the regulated recruitment of telomerase and the regulated dissociation of telomerase from the telomere end at the appropriate time in the cell cycle. We use yeast and mouse models to dissect the conserved underlying mechanism that establishes the telomere length equilibrium. A sophisticated understanding of these mechanisms will allow new approaches to treat telomere-mediated disease.
About the Speaker
Carol Greider received a B.A. from UC Santa Barbara in 1983 and a Ph.D. in 1987 from UC Berkeley. In 1984, together with Elizabeth Blackburn, she discovered telomerase, an enzyme that maintains chromosome ends. In 1988, Greider was appointed as a Fellow at Cold Spring Harbor Laboratory, and in 1994 was promoted to investigator. In 1997, she moved to the Johns Hopkins University School of Medicine. In 2004, she was appointed as the Daniel Nathans Professor and director of the Department of Molecular Biology and Genetics at Johns Hopkins University. Greider’s lab currently studies telomeres and telomerase in cancer and age-related degenerative disease. Greider shared the Nobel Prize in Physiology or Medicine with Blackburn and Jack Szostak in 2009.
https://wn.com/Carol_Greider_Umd_Bioscience_Day_2016_Young_Lecture
University of Maryland Bioscience Day 2016
DR. ERIK B. AND MRS. JOYCE D.C. YOUNG LECTURE
"Telomerase and the regulation of telomere length equilibrium"
by
CAROL GREIDER
2009 Nobel Laureate in Physiology or Medicine
Daniel Nathans Professor and Director, Department of Molecular Biology & Genetics, Johns Hopkins University School of Medicine
Bloomberg Distinguished Professor, Department of Biology, Johns Hopkins University
Abstract
Telomeres are conserved structures that protect chromosome ends in eukaryotes. Telomeres shorten with cell division, and this shortening is counterbalanced by telomerase, which adds telomere repeats onto chromosome ends. The disruption of telomere length maintenance is associated with both cancer and age-related disease. Inappropriate elongation of telomeres can allow the continued growth of cancer cells. On the other hand, insufficient telomere maintenance causes a spectrum of disease in humans including bone marrow failure, pulmonary fibrosis and immune senescence, collectively known as telomere syndromes. The mechanism that establishes and maintains telomere length equilibrium is not fully understood. This equilibrium involves the regulated recruitment of telomerase and the regulated dissociation of telomerase from the telomere end at the appropriate time in the cell cycle. We use yeast and mouse models to dissect the conserved underlying mechanism that establishes the telomere length equilibrium. A sophisticated understanding of these mechanisms will allow new approaches to treat telomere-mediated disease.
About the Speaker
Carol Greider received a B.A. from UC Santa Barbara in 1983 and a Ph.D. in 1987 from UC Berkeley. In 1984, together with Elizabeth Blackburn, she discovered telomerase, an enzyme that maintains chromosome ends. In 1988, Greider was appointed as a Fellow at Cold Spring Harbor Laboratory, and in 1994 was promoted to investigator. In 1997, she moved to the Johns Hopkins University School of Medicine. In 2004, she was appointed as the Daniel Nathans Professor and director of the Department of Molecular Biology and Genetics at Johns Hopkins University. Greider’s lab currently studies telomeres and telomerase in cancer and age-related degenerative disease. Greider shared the Nobel Prize in Physiology or Medicine with Blackburn and Jack Szostak in 2009.
- published: 07 Nov 2016
- views: 339
0:19
Nobel Laureate Professor Carol W. Greider
- Order: Reorder
- Duration: 0:19
- Uploaded Date: 09 Dec 2009
- views: 722
The 2009 American Nobel Laureates were honored at a luncheon at the American Ambassador's Residence in Stockholm on December 9. All eight were asked to answer ...
The 2009 American Nobel Laureates were honored at a luncheon at the American Ambassador's Residence in Stockholm on December 9. All eight were asked to answer the following question: "What advice would you give to your 20-year-old self on making a real difference in the world, knowing what you know today?" In this clip the 2009 Nobel Laureate in Physiology or Medicine, Professor Carol W. Greider, offers her thoughts on the question. Professor Greider works at the John Hopkins University School of Medicine in Baltimore.
https://wn.com/Nobel_Laureate_Professor_Carol_W._Greider
The 2009 American Nobel Laureates were honored at a luncheon at the American Ambassador's Residence in Stockholm on December 9. All eight were asked to answer the following question: "What advice would you give to your 20-year-old self on making a real difference in the world, knowing what you know today?" In this clip the 2009 Nobel Laureate in Physiology or Medicine, Professor Carol W. Greider, offers her thoughts on the question. Professor Greider works at the John Hopkins University School of Medicine in Baltimore.
- published: 09 Dec 2009
- views: 722
0:41
Carol W. Greider Top # 5 Facts
- Order: Reorder
- Duration: 0:41
- Uploaded Date: 02 Nov 2015
- views: 83
Carol W. Greider Top # 5 Facts
Carol W. Greider Top # 5 Facts
https://wn.com/Carol_W._Greider_Top_5_Facts
Carol W. Greider Top # 5 Facts
- published: 02 Nov 2015
- views: 83
2:41
Carol Greider, Ph.D., Nobel Opening Remarks
- Order: Reorder
- Duration: 2:41
- Uploaded Date: 05 Oct 2009
- views: 4288
Carol Greider, a professor in the Johns Hopkins University School of Medicine and the Daniel Nathans Director of Molecular Biology and Genetics in the schools I...
Carol Greider, a professor in the Johns Hopkins University School of Medicine and the Daniel Nathans Director of Molecular Biology and Genetics in the schools Institute for Basic Biomedical Sciences, has been awarded a share of this years Nobel Prize in Physiology or Medicine.
The Royal Swedish Academy of Sciences recognized Greider for her 1984 discovery of telomerase, an enzyme that maintains the length and integrity of chromosome ends and is critical for the health and survival of all living cells and organisms.
The discovery important and of itself for increasing our understanding of how cells work also has turned out to have far-reaching implications for the investigation of cancer and certain aging-related diseases.
She shares the Nobel with Eizabeth Blackburn, a professor of biochemistry and biophysics at the University of California, San Francisco, and Jack Szostack, Ph.D., of Harvard Medical School.
Here are excerpts from Greiders comments at an Oct. 5 news conference following the announcement.
https://wn.com/Carol_Greider,_Ph.D.,_Nobel_Opening_Remarks
Carol Greider, a professor in the Johns Hopkins University School of Medicine and the Daniel Nathans Director of Molecular Biology and Genetics in the schools Institute for Basic Biomedical Sciences, has been awarded a share of this years Nobel Prize in Physiology or Medicine.
The Royal Swedish Academy of Sciences recognized Greider for her 1984 discovery of telomerase, an enzyme that maintains the length and integrity of chromosome ends and is critical for the health and survival of all living cells and organisms.
The discovery important and of itself for increasing our understanding of how cells work also has turned out to have far-reaching implications for the investigation of cancer and certain aging-related diseases.
She shares the Nobel with Eizabeth Blackburn, a professor of biochemistry and biophysics at the University of California, San Francisco, and Jack Szostack, Ph.D., of Harvard Medical School.
Here are excerpts from Greiders comments at an Oct. 5 news conference following the announcement.
- published: 05 Oct 2009
- views: 4288
15:12
Carol Greider, Ph.D. - Discovering Telomerase and Winning the Nobel Prize
- Order: Reorder
- Duration: 15:12
- Uploaded Date: 03 Oct 2017
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This prominent molecular biologist at Johns Hopkins won the Nobel Prize in 2009 for her discovery of the key chromosomal enzyme, telomerase. Learn about this ...
This prominent molecular biologist at Johns Hopkins won the Nobel Prize in 2009 for her discovery of the key chromosomal enzyme, telomerase. Learn about this pioneering researcher's challenging road to her breakthrough discovery.
https://wn.com/Carol_Greider,_Ph.D._Discovering_Telomerase_And_Winning_The_Nobel_Prize
This prominent molecular biologist at Johns Hopkins won the Nobel Prize in 2009 for her discovery of the key chromosomal enzyme, telomerase. Learn about this pioneering researcher's challenging road to her breakthrough discovery.
- published: 03 Oct 2017
- views: 6280
2:35
Interview with Carol Greider on winning the 2009 Nobel Prize in Physiology or Medicine
October 5, 2009- Carol Greider, Ph.D., 48, one of the worlds pioneering researchers on the...
published: 05 Oct 2009
Interview with Carol Greider on winning the 2009 Nobel Prize in Physiology or Medicine
Interview with Carol Greider on winning the 2009 Nobel Prize in Physiology or Medicine
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October 5, 2009- Carol Greider, Ph.D., 48, one of the worlds pioneering researchers on the structure of chromosome ends known as telomeres, today was awarded the 2009 Nobel Prize in Physiology or Medicine by the Royal Swedish Academy of Sciences. The Academy recognized her for her 1984 discovery of telomerase (ta-LAW-mer-ace), an enzyme that maintains the length and integrity of chromosome ends and is critical for the health and survival of all living cells and organisms.
http://www.hopkinsmedicine.org/
10:50
Interview with Elizabeth H. Blackburn, Ph.D., and Carol Greider, Ph.D.
Annual Meeting 2010 Episode __: Recipients of the 2009 Nobel Prize in Physiology or Medici...
published: 19 Apr 2010
Interview with Elizabeth H. Blackburn, Ph.D., and Carol Greider, Ph.D.
Interview with Elizabeth H. Blackburn, Ph.D., and Carol Greider, Ph.D.
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Annual Meeting 2010 Episode __: Recipients of the 2009 Nobel Prize in Physiology or Medicine, Elizabeth H. Blackburn, Ph.D., and Carol Greider, Ph.D., talk about their discovery of how chromosomes are protected by telomeres and the enzyme telomerase and the honor of receiving the Nobel Prize.
25:00
Big Think Interview With Carol Greider | Big Think
Big Think Interview With Carol Greider
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Big Think Interview With Carol Greider | Big Think
Big Think Interview With Carol Greider | Big Think
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Big Think Interview With Carol Greider
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A conversation with the Johns Hopkins University molecular biologist and co-winner of the 2009 Nobel Prize in Medicine.
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Carol W. Greider:
Carol W. Greider is the Daniel Nathans Professor & Director of Molecular Biology & Genetics at Johns Hopkins University. Her research on telomerase (an enzyme she helped discover) and telomere function won her a 2009 Nobel Prize in Medicine. Prior to joining the Johns Hopkins faculty, she obtained a Ph.D. in Molecular Biology from the University of California, Berkeley, in 1997, and was a faculty member at the Cold Spring Harbor Laboratory. She is a member of the National Academy of Sciences and a recipient of the 1998 Gairdner Foundation International Award.
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TRANSCRIPT:
Question: Have you encountered any gender-specific obstacles as a scientist?
Carol Greider: I think that that's a very complicated kind of question, because although I really feel like I never had a particular obstacle that I had to overcome as a female scientist—I never felt that I was singled out or had anything done against me—I do see that when one looks at where women are in science that there is a very large discrepancy, and that there does seem to be an inability for women to get to higher echelons in the scientific hierarchy or in academia. So I think that although I didn't feel like I had anything done personally to me, I think that there may be more subtle social interactions at play in the scientific world that does have a little bit of a negative effect on women advancing in their careers.
Question: What can be done to remove these obstacles?
Carol Greider: I think that as more women get into higher levels of science, and as it's very clear to younger women coming into the field that yes, it is possible to get to the higher ranks, that will help. And also I think that the way that women run meetings, and when the power structure is such that you have a larger representation of women at higher levels, that the conversation may change somewhat. And so that could also be helpful moving forward.
Question: What is your advice to female scientists starting out today?
Carol Greider: Just follow what you're excited about. I would say the same thing to female scientists as to male scientists, to all young people, really: the fun thing is to be able to do something that excites you. A lot of times what we do is a lot of hard work, but hard work is actually okay if you really are engaged in it. And so that really, I think, is the main thing, is find something that you're passionate about and be able to follow that.
Question: How did it feel to win the Nobel Prize?
Carol Greider: That was very exciting. It was a tremendous honor to get a phone call from Stockholm and to share it with Elizabeth Blackburn, who I've worked with for many years, as well as Jack Szostak. So I was very excited, and I was very happy that I got to share the day with my children. I was able to wake them up at five o'clock in the morning after I got this phone call and to have them there with me to share and to celebrate.
Question: What role did you and your co-winners each play in the prizewinning research?
Carol Greider: Yeah, Liz Blackburn and Jack Szostak had a collaboration in the early 1980s where they were interested in trying to understand the function of telomeres. And they had a collaboration which was a cross-country collaboration with one in Berkeley and the other one in Boston. And they would call each other up on the phone and explain experiments and send materials back and forth. And that collaboration resulted in this idea that there may be some way that the cells have of maintaining their chromosome ends. It was known that chromosome ends would shorten every time a cell divided, and in doing a collaboration to try and understand the functional components that make up the telomeres they proposed that there may be an enzyme that lengthens telomeres. And so then when I went to graduate school at U.C. Berkeley and I met Liz Blackburn, that was the project—after I had worked on a smaller project in her lab—that was the project that I thought was the most exciting to follow up on and find out, is there really going to be this hypothesized enzyme which can lengthen telomeres? So that's when I started to work with Liz Blackburn, and it was together in her laboratory that we discovered the enzyme telomerase.
Read the full transcript at https://bigthink.com/videos/big-think-interview-with-carol-greider/
2:36
Telomeres - Research by Carol W. Greider
Carol W. Greider - The pioneered research on the structure of telomeres, the ends of the c...
published: 14 Dec 2020
Telomeres - Research by Carol W. Greider
Telomeres - Research by Carol W. Greider
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Carol W. Greider - The pioneered research on the structure of telomeres, the ends of the chromosomes.
She was awarded the 2009 Nobel Prize for Physiology or Medicine, along with Blackburn and Jack W. Szostak, for their discovery that telomeres are protected from progressive shortening by the enzyme telomerase.
Note:
Carol W. Greider is an independent researcher and not associated with Jeunesse Global products. This video is only for educational purposes. This video is also not for any youtube advertisement monetization.
More info on telomere supplementary product:
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2:20
One Geneticist, Two X Chromosomes | Carol W. Greider | Big Think
One Geneticist, Two X Chromosomes
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One Geneticist, Two X Chromosomes | Carol W. Greider | Big Think
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One Geneticist, Two X Chromosomes
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The Nobel Prize-winning molecular biologist weighs in on gender discrimination in science and advises young women entering the profession.
----------------------------------------------------------------------------------
Carol W. Greider:
Carol W. Greider is the Daniel Nathans Professor & Director of Molecular Biology & Genetics at Johns Hopkins University. Her research on telomerase (an enzyme she helped discover) and telomere function won her a 2009 Nobel Prize in Medicine. Prior to joining the Johns Hopkins faculty, she obtained a Ph.D. in Molecular Biology from the University of California, Berkeley, in 1997, and was a faculty member at the Cold Spring Harbor Laboratory. She is a member of the National Academy of Sciences and a recipient of the 1998 Gairdner Foundation International Award.
----------------------------------------------------------------------------------
TRANSCRIPT:
Question: Have you encountered any gender-specific obstacles as a scientist?
Carol Greider: I think that that's a very complicated kind of question, because although I really feel like I never had a particular obstacle that I had to overcome as a female scientist—I never felt that I was singled out or had anything done against me—I do see that when one looks at where women are in science that there is a very large discrepancy, and that there does seem to be an inability for women to get to higher echelons in the scientific hierarchy or in academia. So I think that although I didn't feel like I had anything done personally to me, I think that there may be more subtle social interactions at play in the scientific world that does have a little bit of a negative effect on women advancing in their careers.
Question: What can be done to remove these obstacles?
Carol Greider: I think that as more women get into higher levels of science, and as it's very clear to younger women coming into the field that yes, it is possible to get to the higher ranks, that will help. And also I think that the way that women run meetings, and when the power structure is such that you have a larger representation of women at higher levels, that the conversation may change somewhat. And so that could also be helpful moving forward.
Question: What is your advice to female scientists starting out today?
Carol Greider: Just follow what you're excited about. I would say the same thing to female scientists as to male scientists, to all young people, really: the fun thing is to be able to do something that excites you. A lot of times what we do is a lot of hard work, but hard work is actually okay if you really are engaged in it. And so that really, I think, is the main thing, is find something that you're passionate about and be able to follow that.
Recorded November 10th, 2009
Interviewed by Austin Allen
1:03:47
Carol Greider - UMD Bioscience Day 2016 Young Lecture
University of Maryland Bioscience Day 2016
DR. ERIK B. AND MRS. JOYCE D.C. YOUNG LECTURE
...
published: 07 Nov 2016
Carol Greider - UMD Bioscience Day 2016 Young Lecture
Carol Greider - UMD Bioscience Day 2016 Young Lecture
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University of Maryland Bioscience Day 2016
DR. ERIK B. AND MRS. JOYCE D.C. YOUNG LECTURE
"Telomerase and the regulation of telomere length equilibrium"
by
CAROL GREIDER
2009 Nobel Laureate in Physiology or Medicine
Daniel Nathans Professor and Director, Department of Molecular Biology & Genetics, Johns Hopkins University School of Medicine
Bloomberg Distinguished Professor, Department of Biology, Johns Hopkins University
Abstract
Telomeres are conserved structures that protect chromosome ends in eukaryotes. Telomeres shorten with cell division, and this shortening is counterbalanced by telomerase, which adds telomere repeats onto chromosome ends. The disruption of telomere length maintenance is associated with both cancer and age-related disease. Inappropriate elongation of telomeres can allow the continued growth of cancer cells. On the other hand, insufficient telomere maintenance causes a spectrum of disease in humans including bone marrow failure, pulmonary fibrosis and immune senescence, collectively known as telomere syndromes. The mechanism that establishes and maintains telomere length equilibrium is not fully understood. This equilibrium involves the regulated recruitment of telomerase and the regulated dissociation of telomerase from the telomere end at the appropriate time in the cell cycle. We use yeast and mouse models to dissect the conserved underlying mechanism that establishes the telomere length equilibrium. A sophisticated understanding of these mechanisms will allow new approaches to treat telomere-mediated disease.
About the Speaker
Carol Greider received a B.A. from UC Santa Barbara in 1983 and a Ph.D. in 1987 from UC Berkeley. In 1984, together with Elizabeth Blackburn, she discovered telomerase, an enzyme that maintains chromosome ends. In 1988, Greider was appointed as a Fellow at Cold Spring Harbor Laboratory, and in 1994 was promoted to investigator. In 1997, she moved to the Johns Hopkins University School of Medicine. In 2004, she was appointed as the Daniel Nathans Professor and director of the Department of Molecular Biology and Genetics at Johns Hopkins University. Greider’s lab currently studies telomeres and telomerase in cancer and age-related degenerative disease. Greider shared the Nobel Prize in Physiology or Medicine with Blackburn and Jack Szostak in 2009.
0:19
Nobel Laureate Professor Carol W. Greider
The 2009 American Nobel Laureates were honored at a luncheon at the American Ambassador's ...
published: 09 Dec 2009
Nobel Laureate Professor Carol W. Greider
Nobel Laureate Professor Carol W. Greider
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The 2009 American Nobel Laureates were honored at a luncheon at the American Ambassador's Residence in Stockholm on December 9. All eight were asked to answer the following question: "What advice would you give to your 20-year-old self on making a real difference in the world, knowing what you know today?" In this clip the 2009 Nobel Laureate in Physiology or Medicine, Professor Carol W. Greider, offers her thoughts on the question. Professor Greider works at the John Hopkins University School of Medicine in Baltimore.
0:41
Carol W. Greider Top # 5 Facts
Carol W. Greider Top # 5 Facts
published: 02 Nov 2015
Carol W. Greider Top # 5 Facts
Carol W. Greider Top # 5 Facts
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Carol W. Greider Top # 5 Facts
2:41
Carol Greider, Ph.D., Nobel Opening Remarks
Carol Greider, a professor in the Johns Hopkins University School of Medicine and the Dani...
published: 05 Oct 2009
Carol Greider, Ph.D., Nobel Opening Remarks
Carol Greider, Ph.D., Nobel Opening Remarks
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Carol Greider, a professor in the Johns Hopkins University School of Medicine and the Daniel Nathans Director of Molecular Biology and Genetics in the schools Institute for Basic Biomedical Sciences, has been awarded a share of this years Nobel Prize in Physiology or Medicine.
The Royal Swedish Academy of Sciences recognized Greider for her 1984 discovery of telomerase, an enzyme that maintains the length and integrity of chromosome ends and is critical for the health and survival of all living cells and organisms.
The discovery important and of itself for increasing our understanding of how cells work also has turned out to have far-reaching implications for the investigation of cancer and certain aging-related diseases.
She shares the Nobel with Eizabeth Blackburn, a professor of biochemistry and biophysics at the University of California, San Francisco, and Jack Szostack, Ph.D., of Harvard Medical School.
Here are excerpts from Greiders comments at an Oct. 5 news conference following the announcement.
15:12
Carol Greider, Ph.D. - Discovering Telomerase and Winning the Nobel Prize
This prominent molecular biologist at Johns Hopkins won the Nobel Prize in 2009 for her di...
published: 03 Oct 2017
Carol Greider, Ph.D. - Discovering Telomerase and Winning the Nobel Prize
Carol Greider, Ph.D. - Discovering Telomerase and Winning the Nobel Prize
- Report rights infringement
- published: 03 Oct 2017
- views: 6280
This prominent molecular biologist at Johns Hopkins won the Nobel Prize in 2009 for her discovery of the key chromosomal enzyme, telomerase. Learn about this pioneering researcher's challenging road to her breakthrough discovery.
Carol W. Greider
Carolyn Widney "Carol" Greider (born April 15, 1961) is an American molecular biologist. She is a Bloomberg Distinguished Professor, Daniel Nathans Professor and Director of Molecular Biology and Genetics at Johns Hopkins University. She discovered the enzyme telomerase in 1984, when she was a graduate student of Elizabeth Blackburn at the University of California, Berkeley. Greider pioneered research on the structure of telomeres, the ends of the chromosomes. She was awarded the 2009 Nobel Prize for Physiology or Medicine, along with Blackburn and Jack W. Szostak, for their discovery that telomeres are protected from progressive shortening by the enzyme telomerase.
Early life and education
Greider was born in San Diego, California. Her father, Kenneth Greider, was a physics professor. Her family moved from San Diego to Davis, California, where she spent many of her early years and graduated from Davis Senior High School in 1979. She graduated from the College of Creative Studies at the University of California, Santa Barbara, with a B.A. in biology in 1983. During this time she also studied at the University of Göttingen and made significant discoveries there.
This page contains text from Wikipedia, the Free Encyclopedia - https://wn.com/Carol_W._Greider
Interview with Carol Greider on winning the 2009 N...
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Big Think Interview With Carol Greider | Big Thin...
Telomeres - Research by Carol W. Greider...
One Geneticist, Two X Chromosomes | Carol W. Greid...
Carol Greider - UMD Bioscience Day 2016 Young Lect...
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Stacker compiled a list of the colleges whose graduates earn the most, using 2021 data—released in 2023—from PayScale ... You may also like ... #100. Carleton College ... The school has also produced a Nobel Prize winner—Carol W. Greider—who won the award in 2009.
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