Duloxetinum
Appearance
Cave: notitiae huius paginae nec praescriptiones nec consilia medica sunt. |
Cognitores | |
---|---|
ChemSpider | 54822 |
PubChem | 60835 |
DrugBank | DB00476 |
Natura chemica | |
Formula chemica | C 18H 19NOS |
Massa molaris | 297.42 g/mol |
Natura pharmacologica | |
Codex ATC | N06AX21 (WHO) |
Semivita biologica | 12 h |
Metabolismus | iecore (hepaticus): CYP1A2, CYP2D6 |
Excretio | renibus (70%), faecibus (20%) |
Ad usum therapeuticum | |
Applicatio | per os |
Duloxetinum est antidepressivum et inhibitor reabsorptionis serotonini noradrenalinique[1].
Pharmacocinetica
[recensere | fontem recensere]Semivita biologica .[2] 12 h est. Duloxetinum substratum cytochromatum CYP1A2 et CYP2D6 est. Excretio est maiore in parte per renes (70%), minore per faeces (20%).
Notae
[recensere | fontem recensere]- ↑ Wong D. T., Bymaster F. P. (2002). "Dual serotonin and noradrenaline uptake inhibitor class of antidepressants potential for greater efficacy or just hype?". Progress in drug research 58: 169-22
- ↑ http://goldbook.iupac.org/B00658.html
Nexus interni
Nexus externi
[recensere | fontem recensere]- drugs.com cum monographia Duloxetini (Anglice)