The International Genome Sample Resource The 1000 Genomes Project created a catalogue of common human genetic variation, using openly consented samples from people who declared themselves to be healthy. The reference data resources generated by the project remain heavily used by the biomedical science community. The International Genome Sample Resource (IGSR) maintains and shares the human genetic
In a perspective piece published in Cell this week (January 14), Eric Lander, president and director of the Broad Institute of MIT and Harvard, outlined the history of achievements behind the precision gene-editing technique known as CRISPR. The problem is, the Broad is a copatentee embroiled in an intellectual property battle being investigated by the US Patent and Trademark Office (USPTO). And L
CRISPR Overview Bacteria have an interesting adaptive immune response that detects and eliminates foreign DNA, which scientists have modified for a wide range of genome engineering techniques. Collectively, these techniques are referred to as CRISPR (Clustered Regularly Interspaced Short Palindromic Repeat) technologies. Before CRISPR, genome engineering approaches like zinc finger nucleases (ZFNs
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