Regulation of XAF1 expression in human colon cancer cell by interferon beta: activation by the transcription regulator STAT1 (Q24301327)

Interferon regulatory factor 1

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XIAP associated factor 1

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Signal transducer and activator of transcription 1

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response to interferon-beta

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Yunwei Sun

1

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Liang Qiao

2

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Harry Hua-Xiang Xia

3

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Marie C M Lin

4

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Bing Zou

5

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Yaozong Yuan

6

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Senlin Zhu

7

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Qing Gu

8

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Ting Kin Cheung

9

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Hsiang Fu Kung

10

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Man Fung Yuen

11

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Annie Oo Chan

12

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Benjamin C Y Wong

Alpha-interferon and its effects on signal transduction pathways

13

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language of work or name

English

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publication date

18 February 2008

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published in

Cancer Letters

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volume

260

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issue

1-2

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page(s)

62-71

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cites work

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Expression and genetic analysis of XIAP-associated factor 1 (XAF1) in cancer cell lines

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Interferon from 1981 to 1986

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Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation

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STAT proteins and transcriptional responses to extracellular signals

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CREB regulates MHC class II expression in a CIITA-dependent manner

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XIAP: apoptotic brake and promising therapeutic target.

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Identification of XAF1 as an antagonist of XIAP anti-Caspase activity

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The protein tyrosine kinase JAK1 complements defects in interferon-alpha/beta and -gamma signal transduction

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Stats: transcriptional control and biological impact

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All-trans retinoic acid induces XAF1 expression through an interferon regulatory factor-1 element in colon cancer

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Correlation between the single-site CpG methylation and expression silencing of the XAF1 gene in human gastric and colon cancers.

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Superoxide in apoptosis. Mitochondrial generation triggered by cytochrome c loss

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Protein kinase C-delta (PKC-delta ) is activated by type I interferons and mediates phosphorylation of Stat1 on serine 727.

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Small ISGs coming forward

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