YY1 transcription factor (Q21096253)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P25490

C2H2-type Zinc finger protein, YY-1-like

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P25490

Zinc finger C2H2-type, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25490&geneProductId=UniProtKB:P25490

3 references

24 April 2018

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25490&geneProductId=UniProtKB:P25490

24 April 2018

YY1 tethers Xist RNA to the inactive X nucleation center

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25490&geneProductId=UniProtKB:P25490

transcription corepressor activity

1 reference

8 April 2019

Transcriptional repression by YY1, a human GLI-Krüppel-related protein, and relief of repression by adenovirus E1A protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25490

transcription coactivator activity

1 reference

8 April 2019

Isolation of a candidate repressor/activator, NF-E1 (YY-1, delta), that binds to the immunoglobulin kappa 3' enhancer and the immunoglobulin heavy-chain mu E1 site

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25490

zinc ion binding

1 reference

8 April 2019

Transcriptional repression by YY1, a human GLI-Krüppel-related protein, and relief of repression by adenovirus E1A protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25490

metal ion binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25490

1 reference

8 April 2019

protein binding

10 references

8 April 2019

PARP-10, a novel Myc-interacting protein with poly(ADP-ribose) polymerase activity, inhibits transformation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25490

8 April 2019

Yeast two-hybrid cloning of a novel zinc finger protein that interacts with the multifunctional transcription factor YY1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25490

8 April 2019

Regulation of DU145 prostate cancer cell growth by Scm-like with four mbt domains 2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25490

8 April 2019

Adenovirus E1A proteins interact with the cellular YY1 transcription factor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25490

8 April 2019

RYBP, a new repressor protein that interacts with components of the mammalian Polycomb complex, and with the transcription factor YY1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25490

8 April 2019

A High-Density Map for Navigating the Human Polycomb Complexome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25490

8 April 2019

Loss-of-Function Mutations in YY1AP1 Lead to Grange Syndrome and a Fibromuscular Dysplasia-Like Vascular Disease

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25490

8 April 2019

Beta-arrestin1 regulates zebrafish hematopoiesis through binding to YY1 and relieving polycomb group repression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25490

8 April 2019

A YY1-INO80 complex regulates genomic stability through homologous recombination-based repair

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25490

8 April 2019

YY1AP, a novel co-activator of YY1.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25490

four-way junction DNA binding

1 reference

8 April 2019

A YY1-INO80 complex regulates genomic stability through homologous recombination-based repair

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25490

cis-regulatory region sequence-specific DNA binding

1 reference

8 April 2019

SMAD-mediated modulation of YY1 activity regulates the BMP response and cardiac-specific expression of a GATA4/5/6-dependent chick Nkx2.5 enhancer

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25490

RNA binding

1 reference

8 April 2019

YY1 tethers Xist RNA to the inactive X nucleation center

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25490

nucleic acid binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25490

1 reference

8 April 2019

SMAD binding

1 reference

8 April 2019

SMAD-mediated modulation of YY1 activity regulates the BMP response and cardiac-specific expression of a GATA4/5/6-dependent chick Nkx2.5 enhancer

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25490

cis-regulatory region sequence-specific DNA binding

1 reference

8 April 2019

Enhanceosome formation over the beta interferon promoter underlies a remote-control mechanism mediated by YY1 and YY2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25490

RNA polymerase II cis-regulatory region sequence-specific DNA binding

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25490&geneProductId=UniProtKB:P25490

DNA-binding transcription repressor activity, RNA polymerase II-specific

4 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25490&geneProductId=UniProtKB:P25490

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25490&geneProductId=UniProtKB:P25490

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25490

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25490

sequence-specific DNA binding

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25490&geneProductId=UniProtKB:P25490

DNA-binding transcription factor activity, RNA polymerase II-specific

A census of human transcription factors: function, expression and evolution

2 references

8 April 2019

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25490

Norwegian University of Science and Technology, Systems Biology team

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25490

histone deacetylase binding

ISA

1 reference

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25490&geneProductId=UniProtKB:P25490

DNA-binding transcription repressor activity, RNA polymerase II-specific

6 references

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25490&geneProductId=UniProtKB:P25490

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25490&geneProductId=UniProtKB:P25490

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25490&geneProductId=UniProtKB:P25490

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25490&geneProductId=UniProtKB:P25490

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25490&geneProductId=UniProtKB:P25490

7 November 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25490&geneProductId=UniProtKB:P25490

DNA binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25490

4 references

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25490

8 April 2019

YY1 tethers Xist RNA to the inactive X nucleation center

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25490

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25490

DNA-binding transcription repressor activity, RNA polymerase II-specific

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25490

DNA-binding transcription factor activity

ISS

1 reference

1 January 2018

Isolation of a candidate repressor/activator, NF-E1 (YY-1, delta), that binds to the immunoglobulin kappa 3' enhancer and the immunoglobulin heavy-chain mu E1 site

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25490

cell component

Ino80 complex

nucleus

Nuclear factor κB subunits RelB and cRel negatively regulate Toll-like receptor 3-mediated β-interferon production via induction of transcriptional repressor protein YY1

6 references

24 April 2018

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25490&geneProductId=UniProtKB:P25490

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25490&geneProductId=UniProtKB:P25490

24 April 2018

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25490&geneProductId=UniProtKB:P25490

24 April 2018

Enhanceosome formation over the beta interferon promoter underlies a remote-control mechanism mediated by YY1 and YY2

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25490&geneProductId=UniProtKB:P25490

24 April 2018

A YY1-INO80 complex regulates genomic stability through homologous recombination-based repair

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25490&geneProductId=UniProtKB:P25490

24 April 2018

Nucleolar localization of human methionyl-tRNA synthetase and its role in ribosomal RNA synthesis

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25490&geneProductId=UniProtKB:P25490

nucleoplasm

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25490

1 reference

8 April 2019

transcription regulator complex

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25490&geneProductId=UniProtKB:P25490

cytoplasm

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25490

PcG protein complex

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25490&geneProductId=UniProtKB:P25490

nucleus

Nuclear factor κB subunits RelB and cRel negatively regulate Toll-like receptor 3-mediated β-interferon production via induction of transcriptional repressor protein YY1

7 references

8 April 2019

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25490

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25490

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25490

8 April 2019

Enhanceosome formation over the beta interferon promoter underlies a remote-control mechanism mediated by YY1 and YY2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25490

8 April 2019

A YY1-INO80 complex regulates genomic stability through homologous recombination-based repair

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25490

8 April 2019

Nucleolar localization of human methionyl-tRNA synthetase and its role in ribosomal RNA synthesis

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25490

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25490

PcG protein complex

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25490

biological process

cell differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25490

1 reference

8 April 2019

DNA recombination

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25490

1 reference

8 April 2019

regulation of transcription, DNA-templated

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25490

cellular response to UV

1 reference

8 April 2019

A YY1-INO80 complex regulates genomic stability through homologous recombination-based repair

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25490

negative regulation of gene expression

1 reference

8 April 2019

Nuclear factor κB subunits RelB and cRel negatively regulate Toll-like receptor 3-mediated β-interferon production via induction of transcriptional repressor protein YY1

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25490

transcription, DNA-templated

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25490&geneProductId=UniProtKB:P25490

1 reference

24 April 2018

cellular response to DNA damage stimulus

A YY1-INO80 complex regulates genomic stability through homologous recombination-based repair

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25490

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25490

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25490

double-strand break repair via homologous recombination

1 reference

8 April 2019

A YY1-INO80 complex regulates genomic stability through homologous recombination-based repair

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25490

DNA repair

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25490

1 reference

8 April 2019

protein deubiquitination

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25490

1 reference

8 April 2019

negative regulation of interferon-beta production

1 reference

8 April 2019

Enhanceosome formation over the beta interferon promoter underlies a remote-control mechanism mediated by YY1 and YY2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25490

negative regulation of transcription by RNA polymerase II

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25490

8 April 2019

Enhanceosome formation over the beta interferon promoter underlies a remote-control mechanism mediated by YY1 and YY2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25490

8 April 2019

Transcriptional up-regulation of the delayed early gene HRS/SRp40 during liver regeneration. Interactions among YY1, GA-binding proteins, and mitogenic signals

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25490

RNA localization

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25490

anterior/posterior pattern specification

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25490

positive regulation of gene expression

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25490

response to prostaglandin F

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25490

positive regulation of transcription by RNA polymerase II

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25490

camera-type eye morphogenesis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25490

chromosome organization

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25490

cellular response to interleukin-1

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25490

negative regulation of pri-miRNA transcription by RNA polymerase II

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25490

response to UV-C

1 reference

1 January 2018

A YY1-INO80 complex regulates genomic stability through homologous recombination-based repair

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25490

negative regulation of cell growth involved in cardiac muscle cell development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25490

has part(s)

Zinc finger C2H2-type

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P25490

Identifiers

MeSH descriptor ID

D050986

subject named as

YY1 Transcription Factor

0 references

0 references

0 references

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

9 August 2016

language of work or name

1 reference

9 August 2016

language of work or name

1 reference

9 August 2016

language of work or name

1 reference

inferred by common MeSH mappings on source and on Wikidata

UMLS 2023