0 ratings 0% found this document useful (0 votes) 525 views 21 pages
2019 RAPHEX Therapy Answer Book
The RAPHEX Therapy Examination 2019 was developed by RAMPS and aligns with ASTRO's curriculum for Radiation Oncology residents. The exam consists of questions based on allocated teaching hours and is intended for residents to review with their instructors. The document also includes information on exam conditions, proctor instructions, and various technical aspects related to radiation therapy.
AI-enhanced title and description
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content,
claim it here .
Available Formats
Download as PDF or read online on Scribd
Go to previous items Go to next items
Save 2019 RAPHEX Therapy Answer Book - Copy For Later
ate] @)ats).4
N0AA0
ie to Vee I )
Answers
Sean L. Berry, Ph.D., Therapy Editorpreface
The RAPHEX Therapy Examination 2019 was prepared by members of the Radiological and Medical Physics
Society of New York (RAMPS, In), the New York chapter ofthe American Association of Physicists in|
Medicine (AAPM).
‘The exam content was updatd in 2016 to match the sylai for teaching Radiation Oncology residents
published by the The American Society for Radiation Oncology (ASTRO) Physics Core Curriculum
Subeommittee (PCCSC). The numbers of questions fo each subject re approximately related tothe number of
teaching hours allocated to each subject
Exam committee
Sean L, Bery, P.D., Therapy Editor
Howard L Amos, PRD.
David Barbe, PhD.
Eugene Lif, PRD.
‘Adam C. Riegel, PLD.
Jussi Sillanpua, PhD.
‘Cheng-Shie Won, PhD, Chie Editor
Additonal questions contbated by
‘Maria Chan, PhO. Martha Malin, Ph.D.
Jeaghwa [Link]. Gregory Niyazow, MS,
Ting Chen, PhD. Brian Wolthuis, MS.
sian Li, PRD. ‘Yuanguang (Andy) Xv, Ph.
Rongtao Ma, M3, $llen Yorke. PuD.
Dennis Mab, PAD.
I you are taking RAPHE, under exam conditions, your proctor wil give you insretions on how to fil |
foul your examinee and site IDs onthe answer sheet. |
+ You have 3 HOURS to complete the exam,
+ Non programmable calculators may be sed
+ Choose the most complete and appropriate answer to each question,
‘We urge residents to review the exam with ther physics instructors
Any comments or correction are appreciated snd shouldbe sent to
(Cheng-Shie Wau, PRD.
Chief altar
esw6i@eume columbia edu
Copyright © 2019 by RAMPS, In. the New York chapter ofthe APM. All igh reserved, No part of this
‘ook may be used or reproduced in any manner whatsoever without writen permission from the publisher oF
the copyright holder.Published in coopes
jon with RAMPS by:
Modical Physi Publishing, Ine.
4555 Helgesen Drive
Madison, WLS3718
1-800-482-5778
mppamedicalphysics. org
vw medealphysics ong
Print in te Ud Stes of Anercntherapy answers
Tob.
D.
ae
mc
Tc.
TB.
A
Te OB
TB,
Te. 8
TH eg.
TB.
Raphex 2019
2000 [Re 3.43 [Remi be = 583,09 [onCiem?)
583.09 [mC Jem] > (100 em) V8 [Ci] x 1/1000 [CVC = 66
‘The joule isthe SI unit for energy, work, nd heat, The gray isthe ST unit fo radiation dose,
and 1Gy= [kg = 1 kg mie
The hai of Co i 5.26 yeas oF 6.12 months, Since A=? ty =n 2/63.12 months
= 0.018 oF 1 per month
In decay, a neuton decays to a proton, an electron, and an ant-neutrno, and possibly,
‘amma rays. With the ational proton, the alomic number is inreased by 1, but the sum of|
projoas andneutons, A, remains unchanged,
40 MeV. The above
nergy equivalent off amu ~931 MeV. Q=931 MeV 0.001
reaction is ecoergi; that i, 4 MeV of energy is released
The energy ofa photon i inversely proportional tothe wavelength of the electromagnetic
wave rpresnting that photon. Ex Tequeney = h(¢/ 3).
Isotopes ar sable, ie. unlikely to deay, they havea neutronsprotons rato of I: for low
atomic mass isotopes and 15:1 for heavy elements. This is refered to as the in, or band, of
stabil. Above the Tine, where there are mote neuttns han protons, beta decay is Hkely, and
below the line, where there are more protons than neutrons, positron decay is ikely.
emission eguies an electron inthe K-sbell to be knocked out by incident electrons
“Therefore, tke minimum energy of incident electtons required fr Ky emission 8 70 keV,
‘The ouput can x-ray tube increases as the square ofthe tbe voltage and linestly with tube
ceument.
CCharacterste x-rays are produced when an inne electron shel vacancy is filled by an auter
sell electron However, sometimes the energy is not released as an x-ray, but transfered to an
cleeton which gets ejected frm the atom. These electrons ae called Auger electwons
There are to types of filtration in an xray tube. The frst is inherent Filtration, which comes
fom the wirdow, housing, an olin the x-ray tube itself. Inherent fication i usually about
0.5 t 1.0 mm aluminum equivalent. The second is added filtration, which consists of metal
shoots added tothe beam to remove low-energy xa)
“The anode ofan x-ray tube is where the x-ray ae produced Since xrays are produced via
bremstraling interactions, «high atomic mimber is desirable. high melting point is
necessary athe vast majority ofthe energy ofthe electrons hing the anode is converted into
hea. A heated Filaments component ofthe x-ray tubes cathodetherapy answers
IB. C.__ Thelikelihood of photoelectric interaction goes as (2/5), so the lower-energy photons are
‘more likely to interact in the material resulting in an exit spoctrum with less intensity for
lowerenergy photons than for higher-enery photons.
rayon enue)
TI4. A, Theclectron boa exiting the accelerating cavity typically hasan enengy spread of 1% 10 2%
‘The 270° bending magnet allows proper focusing of electro of slightly diferent energies
td, therefre, a smaller spo size onthe target. There i also les loss oF electron beam
“intensity with tae 270° bending magnet, albeit at inereased complexity and cost of bling the
linge, When usingonly 3 90° bending magnet, lower-energy electrons would be bent slightly
‘more than high-energy electrons, thus resulting in large spot size onthe x-ray target. A
larger spo size wal, in tua, result in light degradation of beam penumbra sharpness,
which i undesirable
1B, ‘The xray beam or the eletron beam is inident on the dase monitoring chambers. The
‘monitoring syste: consists of several ion chambers ora single chamber with multiple plates.
‘Atnugh the chambers ae usually transmission type Ma parle plate chambers eover
‘he entire bet elindrcal hime chambers have aso been ied in some linac. The
function ofthe ioe chambers to monitor dse rae, integrated dose, and fel symmetry.
TH6, A. Because there willbe bot jaws and MLC in lige B, there wil be less space between the
‘gantry head and the patient ata piven SSD. However, there isn enginering reason why linge
‘A would have leaves that teavel faster or leat positions that canbe defined more precisely.
Similarly, there isno engineering reason why only the MLC in linac A would be abe to move
dynamically during beam-on, 2 occurs for sliding window IMRT and VMAT.
TIT, —_D. Withouta fatonig iter to attenuate the beam, the dose rate wil be higher and the beam
energy will be lower. Since the purpose of a atening fier isto make the photon intensity
“faty" lack of attening filer wil result in higher photon intensities onthe bear central
THB, B, Thefirst combined MR weatment units used Co because exposing the beam of electrons to
an external magni ld i adficul enginecting problem, Even within the patient, the
presence ofthe magnetic field affeots the delivered dose distribution duc to the interections of|
the secondary electrons with the magnetic field. Metal implants may be subject to heating as
well x magaetie lores, and many implants are nt safe fr use in any MR unit
2 aphex 2019therapy answers
TI, A.
mT.
mA
mA
™. vb.
m4.
5. B.
8B.
mA
mB.
mF
Raphex 2019)
Bremsstalng production is proportional to EZ, where isthe incident electron energy and
Zs the atonic umber of the target.
“The eel effet cocurs due to nonuniform sel-ttenuation within the angled anode wed in KV
beam generation. MY beams utilize a uniform target and do not experience the hee effect
According to AAPM TG.-0, mult-laf collimators (MLC) are usually made of tungsten
alloy becaus itis hard, machinable,inexpeasive, and has one ofthe highest densities of any
material,
‘As polyenergetie photon beam traverses a homoyencous material, the Tower-energy photons
ae pefereall attenuated, so the average energy ofthe beam increases. Therefore, the fist
THVL wil betho lest, and the HVL wil increase with increasing thickness ofthe material,
‘Reducing the intensity of the beam by 98% means that at most $% ofthe beam intensity
remains. Malhematiclly: 1=1y(1/2)".1 will be between 4 and 5, For N=, his is 0.03125,
1g G.125% emai). For N= 4, this is 0.0825 Ig (6.25% remains)
Hounsield number H)~ (01— t/a] * 1005
U2 Porat ~ Hater) / Hater) ¥ 1000 = 1000,
\When a chaiged particle interacts with an atom, the influence ofthe particle's coulomb Force
field affects tne atom asa whole, Mos of the interactions are “sol” collisions with outer shell,
clectons rnstering only minaetractions ofthe incident particle's kinetic energy. his
proces is ote referred toa the “continaousslowing-down proximation.”
Fora mono-energeti beam, the HVL is constant. The narowest energy spectrum in the figure
represen the situation where the frst and second HVLs will be the closest,
[Bnergyspecrum A has the largest proportion of low-energy components that would be
removed by a low-energy filter. The other eurves would be much less affected. Removal of
this energy range would harden the beam and inerese the HVL.
Gold is high atomic number and is high-density material, so photeletrc interactions are
significant, sulting in high contrast na CT scan orn @ KV planar image betveen the
fiducial andthe issue in which itis implanted.
{Ina Compton scattering interaction, an incident photon interacts with ee clecton. Some of
the photon exeray’is transfered to he electron, and the rest ofthe energy remains wit the
Scattered photon. Due to conservation of energy and momentum, the electron canbe deflected
between 190 and -90 degrees. The photon can be deflected by any angle. A deflection ange of
180 degresis that which the maximum energy was transfered by the photon to the eleeontherapy answers
133.
34,
35.
16.
ao
38.
jr production oscurs when a photon with energy above a threshold of 1022 MeV interacts
with the Coulomb eld around nucleus, The photon dseppeats, and an electron-positon pair
is produce.
[KERMA is inte eneray released in mater and represen the nengy transfered from
incident photons t electrons tat ae set in motion by a photon-lectron interaction. These
clectrons transfer much oftheir energy locally, but not all atone. The energy is deposited
‘over the pathlength ofthe eletron, so KERMA, the energy initially ansferre, is higher in
the region where tie electrons have not yet deposited ll their dose (the buildup region),
This isthe definition ofthe uence, which is given in unis of Vn?
‘OSLDs provide a means for o-vino dose measurements. However, he response ofthese
dosimeters fade ater iradiation. To accurately and reproducibly measure dose, OSLD.
‘measurement shold be made ater this fading period has ended (onthe order of ebout an
hhour)OSLDs do exhibit linear dose response, energy independence for MV beams, as well
‘8 insensitivity to dose rate and temperature.
[A parallel plate ox chambers the best instrument fr electron output measurements Is ative
‘volume size should he much smaller than the sizeof the euout Aeylndrcal chamber can also
‘be use for higher electon energies provided thatthe eutout is much larger in size than the
collection area of he chamber.
Opticsly stimulated luminescent dosimeters (OSLDs) or thermalumineseent dosimeters
(TLDS) ae the mest common means of measuring the pacemaker dose ona patient. A neuton
‘meters bulky and would only capture the neutron dese Ton chambers use high voltage, which
is dangerous forte patient. Film is inaceurate for small doses.
‘The fll corrected charge reading fom an io chamber is given in AAPM T-S1 as
M= Pag Pp Pele Ppt Moan: Mr the raw chamber reading, and Pj ste factor that
acenunts forthe fect that some of the ionization that occurs in the chamber ress in
recombination betoeit is measured bythe chamber. Pq 8a function of dse rate and bias
voltage and is meesured by acquiring measurements a v0 diferent chamber bas volte
stings.
“The dose recived the film can be related to the emount of light hat ean pass through the
exposed, This known as the optical density. Given fy and fas the transmission values
‘measured before and after an exposure, the optical density ean be defined as:
ND = logo (l/l) this example, OD = logo (5000/S00) = 1,000
Atd~ 1.5m, 100 SSD, 1 MU will deliver 0.97 cGy due to the inverse square law. Ihe data
‘ables improperly report that I eGy is being delivered under these condition, every MU
‘aletlation wil esl ina delivered dose that is 3% les than expected
aphex 2019therapy answers
TF
140, A,
TH.
Ta,
TH, 8.
Tas,
14s,
Raphex 2019
Silicon diodes ate small enough to measure small fields. The parallel plate and farmer
‘camber are to large and would result in volume averaging effects, underreporting the
‘signal Af at ionization chamber is used for measuring exposure i ai, and a well chamber
is used for ealbration of radiosctive sources.
‘TBI treatmeats ae often delivered at extended SSDs, upto 400 em, and in-vivo dosimetry can
indicate whater the patient was positioned atthe correct distance from the source. In-vivo
theta in dagres, As the radius (distance increases, ac length increases
SBRT plans usally exhibit less homogeneous dose distribution within the target, a the
trade-off of minimizing the iradiation of surounding normal isues i to increase the arg
ose inhomogeneity
(Cone output ictor measurement is com
SRS program,
ted tsk performed at the commissioning ofthetherapy answers
THe,
TH.
Ti20.
ria.
vin.
Ti.
Tim.
ri2s.
TI26.
Ti.
‘The conformity index i the ratio of volume receiving prescription dose tothe PT volume,
which measures he normal tissue iadiated to high dose. The gradient index is the ratio of
volume receiving 50% (o 60%) prescription dose tothe PTV volume, which reflects the dose
fall,
‘A well-type ionization chamber is commonly used for calibration of brachytherapy sources
‘The walls ofthe shamber surround the source, approximating a 4x measurement geometry. A
source holder is devised to reproduce the source geometry in relation wo the surrounding
chamber wall. For each brachytherapy source used clinically, the well¢ype chumber should
beara eaibation factor, which i obtained from NIST or an ADCL based on a ealibated
source ofthe sre in,
‘Treatment delivery time wil increase due to exponential decay. The halite of 2h is
74 days, Direct calculation shows: 3 days later) = (Monday) x 2079 = 400 x25
400% 1.028 4s, One can also use the rule of thu that ir decays approimately 1%
per day. Thee dys = 3% deay. 400 x 1.03 = 412s
{A shorter halite (17 days for "Pa versus $9 days for") means the sources will decay
faster, and patie wil need to observe precautions fora shorter window of time. Pd has
the biological advantage ofa higher inital dose rte and a shorter toa treatment ime,
Geiger-Maller meters are the best to detect small amounts of radioactive material
Point A is define as the point 2 em superior from the cervial os and 2 em lateral from the
‘ander. This detinton doesnot account fr difering patient anatomy end could reslt in
‘over or under-dsing the target volume, Prescribing to the target volume accounts for these
‘variations and ysids more consistent doses tothe target
‘The source strength s measured only al the ime of source exchange, which i typically nce
every three montis for ir sources
‘The AAPM TG413 formalism assumes homogeneous medium, therefor using MRI or CT for
imaging will nt change the dose calculation.
The loa dose iscaleuated by multiplying the intl dose rate (IDL) and te isotop’s average
Tite Tyg) Tay Fyn % 144. Therefore, 0.25 Gyr 1.48% 17 dx 24 bel day = 147 Gy,
Pateson-Parker ables may be used for isotopes whos
Ee
ergs are reasonably close o that of
‘The decay constant depends only on the radioactive isotope, not the desig ofthe source
Raphex 2019therapy answers
Tie, &.
Ta. 8.
TI30.
Ta. 8.
Ta. b,
THB. A,
734, 8.
Tas. b,
7136. D,
Raphex 2019
The eveluation san is usually performed 30 days after the implant, since the edema caused by
te trauma tothe prostate fron the implant would likely underestimate the dosimetric indies.
30 days is used tallow the prostate swelling o dissipate
‘The goal of intraoperative radiotherapy (IORT) i to deliver a single high dose of radiation at
the ie of sugry to enhance tumor cane, For HDR TORT, surface applicator are placed in
patients and have guide tubes through which the HDR source ravels. An example ithe HAM
applicator. There are two low-kV x-ray devices curently used for ORT, though these wo
systems share smite inthe way x-rays are produced. One device accelerates an electron
‘beam to the end of tube where it hits a god target, with spherical or Mat applicators attached
to the source pole, The other low-kv xy system uses a minature x-ray tube in a water
cooled cathe, nd tis classified as electronic brachytherapy. Intraoperative electron
radiotherapy OERT) uses electron beams produced froma mobile linge. MY photon energy
{is too high fr ORT.
“The vaginal cylinder can be approximate a a line source. The dose fra point oF interest in
the centr of te length ofthat line source and a perpendicular distance r away, wil all off 5,
Ur. Inthe plan using a 2.6 cm diameter cylinder, the distance from the source to the
preseription print would be 2.6/2+0.5~ 1.8 em. However, forthe delivery it was 3.0/2+
(0.5 = [Link]. Terefre, the delivered dose would be 600 (1.8 /2) = $40 6G.
‘According o NRC 10 CFR Par 35.647, prior to each day of use he source exposure indicator
Tights onthe rmoteaterloadr anit, onthe contol consol, and in the fality rst all be
checked for proper functionality
‘Low-Z materials will may beam energy with minimal seatering, whereas high-Z materials
will scatter the beam with less energy reduction,
The ange of proton beam is defined on the distal side ofthe spreadout Bragg Peak (SOBP)
‘Tho width of fe SOBP is known asthe modulation width
Plans cae optimize to accommodate potential changes in ange, patient setup, and internal
snatomy (ea filling of natal cavity, changes in aspiration). The alr requires additional
Input data inte form of synthetic CTs or ADCT. These plans may be less conformal than less
robust plans but provide plans tha aetally deliver the doses required
Inverpay effets oceur when scanning proton beams interact with moving patient atom,
creating hot and cold spots. Breath hold and respiratory gating reduce intemal patient motion,
Repaining refers to delivering the proton beam multiple times, thereby averaging ou the
delivery.therapy answers
ian.
138,
139,
TH40,
6
‘The range modulators placed imo the beam to create the spread-out Bragg peak (SOBP) so
thata target ean be appropriately covered proximally and distally, An aperture is wed to shape
the beam in the plane perpendicular to te central axis, a nonuniform uence is delivered with
«scanning proton beam, the penetration depth ofthe beam is determined by its energy, and the
use ofa SOPE resis ina relatively high skin dose,
Because the delivered dose in one single fraction deviated by less than $0% ofthe intended
dose AND the ttl dose tobe administered deviated by less than 20% of the presribed total
dose, this qualifies as a recordable, not reportable, even
The RPN is the kvel of isk to the patient if the failure goes undetected. The RPN is the
product ofthe calculated frequency of occurrence, severity and detectability ofthe failure and
tiferent failure modes can be ordered by thei calculated RPNs.
Although ily machine output deviation may lead to dosimetric differences, is outside the
scope ofan IGRT workflow an therefore, would not be part ofa daily IGRT process map.
Raphex 2019