Discussion 1: Integumentary System
Functions, Organs, Diseases
Table of Contents
1. DEFINITION 2. ORGANS AND LAYERS 3. DISEASES
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1. Integumentary System
Invest in your skin. It is going to represent you for a very long time.” — Linden Tyler
INTEGUMENTARY SYSTEM
Integument means “covering”.
Dermatology is a branch of medicine that specializes in diagnosing and treating skin
disorders
THE SKIN
Also called cutaneous membrane
Covers the external surface of the body
Largest and most visible body organ
Multi-layered; made of several different tissue types
Functions
PROTECTION
Against abrasion, water loss, & microorganism
Skin is the first line of defense
CUTANEOUS SENSATION
Sensory receptors that detect heat, cold, touch, pressure, & pain
Sensitivity depends on number of receptors present in an area
TEMP. REGULATION
By controlling blood flow to skin
Sweat glands activated by external temp. or exercise
VIT. D PRODUCTION
Cholesterol in cells of stratum germinativum activated by UV rays then cholesterol changed
to Vit. D
Needed for Ca absorption
EXCRETION
Waste products (small amounts of urea and ammonia) released through sweat
WOUND HEALING
Process of skin repair following injuries such as cuts or tears
Two types: epidermal and deep wound healing
2. Layers and Organs
Layers of Skin
1.Epidermis
2. Dermis
3.Hypodermis
Epidermis
Is the superficial, thinner portion
Composed of epithelial tissue
Composed of keratinized stratified squamous epithelium
Thinkest on the palmar and plantar surfaces
No capillaries
Contains 4 types of cells and 4-5 layers (stratum)
TYPES OF EPIDERMAL CELLS
KERATINOCYTES
most abundant of the epidermal cells
arranged in four or five layers
produce keratin
MELANOCYTES
Produce melanin: pigment that contributes
to skin color and absorbs damaging UV light
LANGERHANS
These cells determine the appropriate
adaptive immune response
(inflammation or tolerance) by interpreting
the micro environmental context in which
they encounter foreign substances.
MERKEL
Receptors for sense of touch
LAYERS OF THE EPIDERMIS
Stratum corneum
Stratum lucidum
Stratum granulosum
Stratum spinosum
Stratum basale/ germinativum
Stratum Corneum
Outermost epidermal layer
Consists of layers of dead keratinocytes
(w/ only keratin left)
Cells continuously shed off or desquamate
and are replaced
Stratum Lucidum
Present in thicker skin
Function is to reduce friction between
the stratum corneum and stratum granulosum.
Latin for "clear layer,"
Stratum Granulosum
These granules contain lipids, which along with the desmosomal connections
Help to form a waterproof barrier that functions to prevent fluid loss from the body.
Stratum Spinosum
Helps make your skin flexible and strong. Between the stratum spinosum layer and the
stratum lucidum layer.
Stratum Germinativum
Also called as stratum basale
Innermost epidermal layer
Where mitosis happen
Produce keratinocytes
Older cells are pushed to undergo keratinization
DERMIS
Second, deeper part of the skin
Composed of fibrous connective tissue
(irregular type)
Contains collagen and elastic fibers
Papillary layer (uneven junction between
epidermis and dermis; contains capillaries
that nourish epidermal cells)
DERMIS CONTAINS
A. Arterioles
Small arteries beneath the epidermis
Smooth muscles permit vasoconstriction
and vasodilation
Bring heat-carrying blood to skin
Constrict during stressful situations to
shunt blood to more vital organs
A. Sensory Receptors
Detect changes that are felt as the cutaneous
senses
Free nerve endings: receptors for pain, heat,
and cold
Encapsulated nerve endings: receptors for touch
and pressure
HYPODERMIS
Subcutaneous Tissue
Superficial fascia
A layer deep to the dermis but not part of the
skin
Contains large blood vessels that supply the skin
Made of areolar connective tissue and adipose
tissue
Connects the dermis to the underlying muscles
Serves as storage deposit for fat
ACCESSORY STRUCTURES
1. HAIR
Also called, “pili”
Present on skin surfaces except
palms, soles, lips, nipples, & parts of external
genitalia
Eyelashes & Eyebrows- protect eyes from
foreign particles
Scalp hair- insulates head from cold &
protects it from sun’s rays
Nasal hair- keep foreign particles out of
nostrils
Made of fused, dead, keratinized
epidermal cells
HAIR
Hair root- found below the surface
Contains blood vessels
Surrounded by hair follicle where hair matrix is found (mitosis takes place)
New epidermal cells produce keratin, get their color from melanin, die, & become
incorporated into hair shaft
Hair shaft- protrudes above the skin surface (through epidermis)
Rate of hair growth: 8-10 mm/month
Arrector Pili muscle- extends from the upper dermis to the side of the hair follicle
Stimulated by cold or fright
Contraction causes goosebumps
SKIN GLANDS
SEBACEOUS GLANDS
also called “oil glands”
Connected to hair follicles or directly to the
skin surface
Secretes sebum
Lipid substance or oil, inhibits the growth
of some bacteria, and prevents of drying of
skin & hair
SUDORIFEROUS GLANDS
Also called “sweat glands”
A. ECCRINE GLANDS
Coiled, tubular glands with ducts that
extend to the skin’s surface, where it opens
into pores
Distributed all over the body
Produce a watery sweat that helps regulate body temperature
SUDORIFEROUS GLANDS
Also called “sweat glands”
B. APOCRINE GLANDS
Limited to the axillary and pubic regions
Produce a thicker sweat often released during emotional stress
Accumulation of secretions result in body odor
CONTENTS OF SWEAT
All sweat glands: H20, Na+, Cl-, urea,
ammonia, amino acids, and glucose
Apocrine glands: plus lipids and proteins
CERUMINOUS GLANDS
Located in the dermis of ear canals
Secretes cerumen or ear wax
Forms a sticky barrier that waterproofs
and inhibits foreign material from entering
the ear canal prevents drying of eardrum
NAILS
Plates of tightly packed, hard, dead &
keratinized cells of the epidermis
Rate of growth: 3 mm/month
FUNCTIONS
Protect the ends of fingers and toes
from mechanical injury
Help in manipulating small objects
Allow scratching
A. Nail Body
Visible part of nail
Transparent with pink nail bed
B. Free Edge
Part of the nail body extending past the end of the finger or toe
C. Nail Root F. Nail Matrix or Nail Follicle
Part not visible - Proximal portion of nail root
Embedded in skin - Contains dividing cells, which produce new nail cells
D. Lunula
Think, white part of nail COMMON DISEASES
E. Cuticle
Stratum corneum of epidermis