Shivaji University, Kolhapur

Question Bank for March 2022 (summer) Examination

Subject Code: 69879 Subject Name: Pharmaceutical Organic Chemistry II (SEM-III)

Common subject Code (if any): BP301T

OBJECTIVE TYPE QUESTIONS (02 Marks)

1. Give a short note on Kekule’s structure of benzene.

2. Execute analytical evidences of structure derivation of benzene.
3. Enlist activating group and deactivating group.
4. Draw the Orbital structure of benzene.
5. Draw the Structure and enlist uses of Chloramine.
6. Draw the Structure and enlist uses of Saccharin.
7. Draw the Structure and enlist uses of BHC.
8. Draw the Structure and enlist uses of DDT.
9. Explain Resonance in Benzene.
10. Execute synthetic evidences of derivation of structure of benzene.
11. Enlist the ortho-para and meta directing groups towards Electrophilic aromatic
substitution.
12. Enlist activating group and deactivating group towards Electrophilic aromatic
substitution.
13. Write a short note on aromatic character of benzene.
14. Give the statement of Huckel’s rule.
15. Why naphthalene is aromatic? Justify in short.
16. Why Benzene is aromatic? Justify in short.
17. Explain why toluene is more readily nitrated than benzene.
18. Explain why phenol is more readily nitrated than benzene.
19. Explain why benzene is more readily nitrated than nitro benzene.
20. Why Alcohol is less acidic than carboxylic acid?
21. Explain basicity of ethylamine and aniline.
22. Draw the resonating structures of Phenol.
23. Why carboxylic acid is more acidic than phenol?
24. Enlist the qualitative tests for phenol with observation.
25. Why alcohol is less acidic than phenol?
26. Draw the structure and enlist uses of resorcinol.
27. Draw the Structure and enlist uses of Cresol.
28. Draw the Structure and enlist uses of Napthol.
29. Draw the Structure and enlist uses of Phenol.
30. Why phenol is more acidic than alcohol?
31. Draw the resonating structures of Aniline.
32. Draw the resonating structures of Aromatic amine.
33. Write any two reactions involving Benzoic acid.
34. Write a note on Hinsberg test.
35. Write a note on Lucas test.
36. Give a short note on ‘Dow Process’.
37. Write the synthetic uses of Aryl Diazonium salts.
38. Define Reichert Meissl (RM) Value and Acetyl value.
39. Define Acid Value and Saponification value.
40. Enlist Significance of Saponification Value and Iodine value.
41. Define Ester Value and Iodine value.
42. Write a short note on Rancidity of oils.
43. Write a short note on Drying of oils.
44. Give any one reaction of fatty acid.
45. Give outline on Hydrogenation of oils
46. Give outline on Hydrolysis of oils.
47. Give outline on Saponification of oils.
48. Give any two reactions of Fatty acids.
49. How will you distinguish between fats and oils.
50. Explain in short any one analytical constant of Fats and oils
51. Write a short note on Rancidification of Fats and oils.
52. Draw the structure of following
1.Triphenylmethane
2. Diphenylmethane
53. Draw the structure & enlist use of Naphthalene.

54. Draw the structure & enlist use of Phenanthrene.

55. Enlist derivatives of Anthracene with its structure.
56. Enlist derivatives of Naphthalene with its structure.
57. Enlist derivatives of Phenanthrene with its structure.
58. Enlist derivatives of Diphenylmethane with its structure.
59. Enlist derivatives of Triphenylmethane with its structure.
60. Write any two method of preparation of Naphthalene.
61. Explain Baeyer’s strain theory with its limitations.
62. Describe stability of Cycloalkanes.
63. Write a note on theory of strainless rings.
64. Write ant two reactions of reactions of cyclopropane.
65. Write ant two reactions of reactions of cyclobutane.

SHORT ANSWER QUESTIONS (05 Marks)

1. Elaborate modern concept of Aromaticity.

2. Discuss any five reactions involving benzene.
3. How will you derive structure of benzene?
4. How will you determine Aromaticity of Organic compounds explain with example.
5. Draw the structure and give its uses of following
1. BHC 2. DDT 3. Chloramine 4. Phenanthraquinone 5. Saccharine

6. Draw the structure and give uses of following

1.Saccharine 2. Phenol 3. Resorcinol 4. 2-naphthol 5. Cresol

7. Elaborate Activity effect of substituent of monosubstituted benzene towards

Electrophilic Aromatic Substitution.
8. Elaborate orientation effect of monosubstituted benzene substituent towards
Electrophilic Aromatic Substitution.
9. Define Aromaticity and give brief outline on Huckel’s rule.
10. Describe the reaction, mechanism involved in Halogenation of benzene.
11. Describe the reaction, mechanism involved in Nitration of benzene.
12. Describe the reaction, mechanism involved in Friedel crafts Alkylation of benzene
with Limitations
13. Describe the reaction, mechanism involved in Friedel crafts Acylation of benzene
with Limitations..
14. Execute different chemical properties of Benzoic acid
15. Illustrate any five methods of preparation of Benzoic acid
16. Write any five methods of preparation of Phenol.
17. Execute any five reactions of Phenol.
18. Illustrate any five reactions of Aromatic amine.
19. Discuss the effect of substituents on basicity of amines with example.
20. Discuss the effect of substituents on acidity of aromatic acids with example.
21. Discuss the effect of substituents on acidity of phenols with example.
22. Draw the structure and enlist the uses of Phenol, cresol, resorcinol, 1-napthol,
Anthracene.
23. Give detail note on any two analytical constants of fats and oils.
24. Illustrate any five reactions of fatty acids.
25. Elaborate chemical properties of oils.
26. Discuss the significance and principle involved in determination of RM value and
Acetyl value.
27. Discuss the significance and principle involved in determination of Acid value and
Ester value.
28. Discuss the significance and principle involved in determination of Iodine value and
Saponification value.
29. Write methods of preparation of Naphthalene.
30. Write chemical reactions involved with Naphthalene.
31. Write methods of preparation of Phenanthrene.
32. Write chemical reactions involved with Phenanthrene.
33. Write methods of preparation of Anthracene.
34. Write chemical reactions involved with Anthracene.
35. Write methods of preparation of Triphenylmethane.
36. Write chemical reactions involved with Diphenylmethane.
37. Write methods of preparation of Diphenylmethane.
38. Write chemical reactions involved with Triphenylmethane.
39. Describe coulson and Moffitt’s modification on theory of strainless rings.

40. Derive Sachse Mohr’s Theory of strainless rings.

41. Explain in details reactions involved with cyclopropane.
42. Explain in details reactions involved with Cyclobutane.
43. Write brief on Stabilities of Baeyer’s strain theory
44. Explain limitation of Baeyer’s strain theory.
45. Illustrate the methods of preparation of cyclopropane.

LONG ANSWER QUESTIONS (10 Marks)

1. Explain Electrophilic substitution reaction; give reaction and mechanism involved

in Friedel crafts alkylation and Friedel craft Acylation.
2. Describe Electrophilic substitution reaction; give reaction and mechanism involved
in Halogenation and Nitration of Benzene.
3. Elaborate mechanism of Electrophilic substitution reaction; give reaction and
mechanism involved in Halogenation and Sulphonation of Benzene.
4. Elaborate a brief note on reactivity and orientation of monosubstituted benzene
compounds towards electrophilic substitution reaction.
5. Summarize any five methods of preparation and reactions of benzoic acid.
6. Summarize any five methods of preparation and reactions of phenol.
7. Summarize any five methods of preparation and reactions of Aromatic amines
8. Explain the effect of substituent’s on
i) Acidity of Phenol
ii) Basicity of Aromatic amines
9. Discuss the effect of substituent on
i) Acidity of Aromatic Acids
ii) Basicity of Aromatic amines
10. State the principle involved in determination of Acid value, Ester value, Iodine
Value, Acetyl value, saponification value.
11. Write methods of preparation and reactions of Naphthalene.
12. Write methods of preparation and reactions of Phenanthrene.
13. Write methods of preparation and reactions of Anthracene.
14. Write methods of preparation and reactions of Diphenylmethane.
15. Write brief on
i) Stabilities of Baeyer’s strain theory with limitations.
ii) Coulson and Moffitt’s Modification