Scribd
Upload
302 views1 page

Pre - Ph.D. Examination Pharmacy: (April-19) (RPH-141)

This document outlines the structure and content of a pre-Ph.D. examination in Pharmaceutical Chemistry. It contains 6 questions, with students required to answer 4 of the questions. The questions cover a range of topics in pharmaceutical chemistry including elimination reactions, cis-trans configurations, carbonium ions, sigmatropic reactions, optical activity, Cahn-Ingold-Prelog rules, combinatorial chemistry techniques, Wagner-Meerwin and Wittig rearrangements, receptor types, drug-receptor interactions, and mechanisms of drug action. Students have 3 hours to complete 4 of the 6 questions worth a total of 100 marks.

Uploaded by

pradeep36
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd
302 views1 page

Pre - Ph.D. Examination Pharmacy: (April-19) (RPH-141)

This document outlines the structure and content of a pre-Ph.D. examination in Pharmaceutical Chemistry. It contains 6 questions, with students required to answer 4 of the questions. The questions cover a range of topics in pharmaceutical chemistry including elimination reactions, cis-trans configurations, carbonium ions, sigmatropic reactions, optical activity, Cahn-Ingold-Prelog rules, combinatorial chemistry techniques, Wagner-Meerwin and Wittig rearrangements, receptor types, drug-receptor interactions, and mechanisms of drug action. Students have 3 hours to complete 4 of the 6 questions worth a total of 100 marks.

Uploaded by

pradeep36
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd

[April-19]

[RPH-141]
[Link].D. EXAMINATION
Pharmacy
PHARMACEUTICAL CHEMISTRY
(Effective from the admitted batch 2018–19)
Time: 3 Hours [Link]: 100
Answer any Four of the following: (4×25=100)
1. a) Discuss about elimination reaction. 10
b) Discuss the stability of cis and trans configuration with
suitable examples. 10
c) Explain about the stability of carbonium ion. 5

2. a) Write a short notes on sigmatropic reactions. 10


b) Write a short note on optical activity. 5
c) Discuss about Cahn-Ingold-Prelog priority rules for E-Z
isomerism. 10

3. Enumerate combinatorial chemistry and its applications in the


field of chemistry. Briefly explain the solid phase combinatorial
techniques, it’s requirements and applications. 25

4. Explain the principle, mechanism and applications of the


following reactions.
a) Wagner – Meerwin rearrangement 13
b) Wittig rearrangement 12

5. Write short notes on the following:


a) Receptor types and isolation 8
b) Drug receptor interaction 8
c) Non empirical electronic parameters 9

6. a) Discuss the various types of drug action. What is meant


by receptor and explain about drug receptor Interaction. 15
b) Write a note on mechanism of drug action. 10

[81R/619]

You might also like