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Molloy College

Rockville Centre, New York

Course Outline

Semester: Fall 2020

Department: Biology, Chemistry, & Env. Studies Faculty: Dr. Chris Massone

Course: CHE 1120 Sections: E Course Title: Organic and Biological Chemistry

CATALOG DESCRIPTION: A survey of organic and biological chemistry with emphasis on the
reactions of the major classes of organic compounds and their role in physiological processes.
PREREQUISTE: High school chemistry within the past 3 years and/or CHE 1090.
Molloy College
Department of Biology, Chemistry, and Environmental Studies

CHE 1120/1130- Organic and Biological Chemistry

Instructor: Dr. Chris Massone

Office Hour: By appointment
Email: [email protected]

Course Goals:
1. Students will state and describe the basic theories of life/analytical sciences.
2. Students will demonstrate effective oral and written communication skills.
3. Students will discuss issues in a rationale way, analyze critically and
evaluate effectively.
4. Students will explain the scientific method as it applies to all scientific
inquiry. Students will perform laboratory skills befitting the course
objectives.
5. Students will exercise appropriate demeanor in both classroom and
laboratory settings creating a safe place for self and others.
6. Students will recognize the impact that scientific data lends to our
understanding of contemporary issues as they politically and/or personally
influence life-decisions. Students will demonstrate social, political, and
ecological awareness and involvement.
Date(s)(Tentative) Topic HW Problems
Sept 9-Sept 16 Acids and Bases 10-8,10,12,14,24,30,32,34,40,42,58

Sept 21-Sept 28 Intro. To Organic Chemistry: 11-2,10,12,14,16,18,24,26,28,30,32,34,36,38

Hydrocarbons

Oct 5 Exam 1 Chpts 10,11

Sept 30-Oct 13 Alcohols, Phenols, Ethers, 12- 2,4,6,8,10,12,14,16,20,22,24,28,30,32,34

Aldehydes and Ketones

Oct 14-Oct 21 Carboxylic Acids, Esters, 14-4,6,8,10,12,16,18,20,22,28, 30,32,34,36,38,

Amines, and Amides 40,42,44,46

Oct 21-Oct 28 Carbohydrates 13-8,10,12,16,18,20,22,24,34,36,38,40,42,44

Nov 4 Exam 2 Chpts 12,14,13

Nov 2-Nov 11 Lipids 15- 6,8,10,20,22,24,32,34,36,42,44,46

Nov 11-Nov 23 Amino Acids, Proteins and 16-6,8,10,12,14,18,22,26,36,38,44,46,48

Enzymes

Nov 23-Dec 2 Nucleic Acids and Protein 17-2,4,8,10,22,28,40,44,52,56

Synthesis

Dec 7 Exam 3 Chpts 15,16,17

Dec 2-Dec 9 Metabolic Pathways and TBA

Energy Production

TBA FINAL EXAM Cumulative

Learning Objectives by Topic:
- Acids and Bases
Upon completion of this topic students should be able to:

Differentiate between acids and bases

Define acids and bases according to the Bronsted-Lowry definition
Differentiate between acids and bases which are strong and which are weak
Explain equilibrium and apply Le’ Chatelier’s principle
Explain the ionization of water and how it affects acidity and basicity
Identify acidity and basicity from the pH scale
Define substances which are buffers

- Introduction to Organic Chemistry: Hydrocarbons

Upon completion of this topic students should be able to:

Identify compounds which are organic

Explain the bonding found in organic compounds
Name and Draw compounds known as alkanes
Explain some of the properties of alkane compounds:
Solubility
Identify compounds which are alkenes and alkynes
Name and Draw compounds which are alkenes and alkynes
Differentiate between cis-trans isomers
Predict products of alkene addition reactions:
Halogenation, Hydration
Identify, Name, and Draw compounds which are aromatic

- Alcohols, Phenols, Ethers, Aldehydes and Ketones

Upon completion of this topic students should be able to:

Identify, Name, and Draw compounds which are alcohols, phenols, and thiols
Identify, Name, and Draw compounds which are ethers
Explain the solubility in water of alcohols, phenols, and ethers:
Predict products of alcohol reactions:
Dehydration, Oxidation, Reduction
Identify, Name, and Draw compounds which are aldehydes and ketones
Explain some of the properties of aldehydes and ketones:
Solubility
- Carboxylic Acids, Esters, Amines, and Amides
Upon completion of this topic students should be able to:

Identify, Name, and Draw compounds which are carboxylic acids

Explain some of the properties of carboxylic acids:
Solubility, Acidity
Identify, Name, and Draw compounds which are esters
Predict what esters are formed from carboxylic acids:
Esterification
Explain some of the properties of esters:
Acid and Base Hydrolysis
Identify, Name, and Draw compounds which are amines
Explain some of the properties of amines and amine salts:
Identify, Name, and Draw compounds which are amides
Explain some of the properties on amides:
Acid and Base Hydrolysis

- Carbohydrates
Upon completion of this topic students should be able to:

Identify the types of carbohydrates

Classify monosaccharides
Identify compounds which are chiral
Draw Fischer Projections for chiral molecules
Identify D and L carbohydrates from Fischer Projections
Identify and Draw Fischer Projections for Glucose, Galactose and Fructose
Draw Haworth Structures from Fischer Projections
Explain some of the properties of monosaccharides
Identify the bonding in disaccharides
Differentiate between  and  disaccharide anomers

- Lipids
Upon completion of this topic students should be able to:

Classify different types of lipids

Identify lipids which are fatty acids
Explain some of the physical properties of fatty acids
Identify lipids which are waxes, fats or oils
Explain some of the physical and chemical properties of fats and oils:
Hydrogenation, Hydrolysis, Saponification
Identify lipids which are phospholipids
Identify lipids which are steroids

- Amino Acids, Proteins, and Enzymes

Upon completion of this topic students should be able to:

Identify compounds which are amino acids

Classify amino acids according to polarity and acidity
Differentiate between amino acid stereoisomers
Discuss the formation of peptides
Explain the levels of protein structure
Define an enzyme
Explain how enzymes work
Discuss the factors affecting enzyme activity:
Temperature, pH, Inhibition

- Nucleic Acids and Protein Synthesis

Upon completion of this topic students should be able to:

Identify the components of nucleic acids

Discuss the primary structure of nucleic acids
Discuss the DNA double helix in terms of:
Complementary Base Pairs and Replication
Explain the three types of RNA
Explain the processes of Transcription and Translation

- Metabolic Pathways and Energy Production

Upon completion of this topic students should be able to:

Describe the stages of metabolism and the role of ATP.

Define anabolic and catabolic reactions.
Identify the sites and products of digestion for carbohydrates, triglycerols, and proteins.
Describe Glycolysis.
Describe the Citric acid cycle and its relation to acetyl CoA.
Describe the electron transport system.
Describe the process of oxidative phosphorylation in the synthesis of ATP.
Describe the oxidation of fatty acids.
Describe the degradation of amino acids.

Text:
“Chemistry: An Introduction to General, Organic, and Biochemistry”; Karen C.
Timberlake, 13th Ed, 2017, Benjamin Cummings Company, New York.

Class Meetings and Content Delivery.

The lecture portion of the class is scheduled to meet in an online synchronous format.
However, in order to afford each of you the maximum flexibility in viewing and learning course
content, we will be holding minimal required meetings. This does not mean that you are going
to be learning the course content on your own! The way that I set up the lecture portion of
CHE 1120 during this past summer was to use a combination of PowerPoint slides that contain
my lecture notes (what I would write out on the board) with audio explanations accompanying
each slide (what I would say if were in the classroom). So, I believe that you will get a very
similar experience to what you would have gotten if we were to meet in a classroom on campus.
Modules will be created that contain all the content for the lecture portion of the course.

Each Monday at 1:50pm, I will be available to answer your questions and provide a verbal
overview of what was covered during the week up to this point. The session will be held via
Zoom (audio only). Although I will make attendance at these sessions optional, your attendance
is strongly encouraged. To help these sessions run as smoothly as possible, I will ask that you
send in your questions ahead of time. The first session will take place on 9/14.

Exams:
There will be 3 lecture exams and a cumulative final exam. The three lecture exams will
make up 45% of your final grade (each exam is 15%) and the final exam will make up 25% of
your final grade. Make up exams will only be given in case of an emergency with proper
documentation. No verbal reasons will be accepted. The dates of the exams will be as
follows:
Monday, October 5th- Exam 1- 1:50-3:20 or 8:00-9:30 PM
Wednesday, November 4th- Exam 2- 1:50-3:20 or 8:00-9:30 PM
Monday, December 7th- Exam 3-1:50-3:20 or 8:00-9:30 PM
I am offering two possible times to take the exams to be as flexible as possible, especially to
accommodate those of you who have lab right after lecture time on Mondays and Wednesdays.
Before each exam, you will have to select the time you will be taking the exam. There is no
advantage taking an exam at one time or the other. I have many versions of exams…..

Exam Sign-Up: Two days before the exam, you must select the time you will take the exam by
sending me an email. If you do not select a time, one will be selected for you.

Proctorio Exam Proctoring:

This course requires one or more proctored exams using Proctorio through Canvas. Students
must be sure to have:
 Access to a quiet, preferably private, space for testing,
 A web camera (USB or internal),
 A microphone (USB or internal), and
 Their Molloy ID card (not their driver’s license) ready for the ID verification process.
 A desktop computer or laptop when taking quizzes and exams using Proctorio (mobile devices are not
compatible, including iPads and mobile phones)
 Download the Chrome browser with the Proctorio extension installed

Students should understand that recording hardware (i.e. web camera and a microphone) is
purchased and controlled by the student. Students are expected to read Molloy College's rules
and expectations for engaging in honest research and coursework while completing assignments
and exams by accessing the Student Academic Integrity webpage. For additional information
about online proctoring with Proctorio, students can visit the Support for Test-Takers and FAQ
page at https://proctorio.com/support.

Proctorio recordings are only available to your instructor and other college officials, and the
extension only runs during the quiz or exam. Therefore, no student privacy rights are violated,
nor is the security of computers or laptops jeopardized. Proctorio is designed to help maintain the
academic integrity of online exams. Proctorio offers 24/7 support and can answer your questions
by chat by clicking the shield icon in Chrome or by email at [email protected].

Pupil Preparation:
Upon completion of a chapter you are expected to hand in the problems assigned for
each chapter (given previously). However, in order to master this course these are not the only
problems you should be doing. Take the time to do all the problems not only in this text but any
other text you may find. These homework assignments count for 10% of the final grade. Note:
Students using an older version or a different version of the textbook are responsible for
obtaining and answering the correct homework problems
Homework Assignments are due as follows:
9/21/20- Chpt 10
9/28/20- Chpt 11
10/13/20- Chpt 12
10/21/20- Chpt 14
11/2/20- Chpt 13
11/11/20- Chpt 15
11/23/20- Chpt 16
12/2/20- Chpt 17

Communicating Across the Curriculum:

Students will illustrate their ability to write and speak in a manner that clearly and
concisely conveys their thoughts. The Communicating Across the Curriculum requirement will
be satisfied through online question and answer sessions and written laboratory reports.

Laboratory:
Students are expected to attend all face-to-face laboratory sessions. No make-up times
are available. Students who miss a face-to-face lab for a documented medical reason (including
not being allowed on campus due to a COVID-19 related issue after following College protocol)
will be given the opportunity to do an additional online lab towards the end of the semester.

Your grade in the laboratory portion of this course will count 20% towards the final grade.
Laboratory policies, procedures and requirements will be given in a subsequent handout.

Note: CHE 1130 students will have the option of doing two short papers or have their exams
count for 5% more each in lieu of the laboratory portion of the course.

COVID-19 College Policy Statements

This course is scheduled to have a face-to-face component, which means that we have weekly
meetings in an assigned space at a designated time. Due to the evolving nature of the pandemic,
it may be necessary to transition this to an online format at the discretion of the instructor. In the
event that this course must transition to an online format for days or weeks, the instructor will
advise you of the format. We may transition to a synchronous online meeting (with designated
meeting times) or asynchronous online meetings (without a designated meeting
time). Attendance will be taken, regardless of format. 

Instructional Seating 
All face-to-face instructional spaces have been modified to account for social distancing.
Wherever possible, unnecessary seating has been removed and desk positioning has been
indicated with floor markings. Out of consideration for the Molloy Community, please refrain
from removing or adjusting seating in instructional spaces. 
Disinfecting Protocol 
All members of the Molloy Community are expected to contribute to a healthy environment.
Therefore, disinfectants, or chemicals that kill germs on surfaces, will be available in all
instructional spaces. Upon arrival in an instructional space, take an available disinfectant wipe
and wipe down the desktop and any hard surfaces in your area, including keyboard, mouse, etc.
At the conclusion of your time in that space, please repeat the process, wiping down
surfaces with a fresh wipe. Wipes should be properly disposed of in the room receptacle. 

Face Covering 
All students are required to wear face coverings in instructional spaces during class. The face
covering must cover both the nose and mouth and must be worn at all Molloy locations while
indoors.   

Attendance 
It is the accepted practice at Molloy College that faculty take attendance in all courses. Students
should notify faculty if an absence is necessary as the result of a serious situation. Failure to
attend class for two (2) consecutive weeks at any point in the semester, without notification of
extenuating circumstances, will result in an administrative withdrawal from the course.  
 
In the case of an online or hybrid course, attendance is considered similarly important.
Therefore, failure to participate in academic activities in any given week is considered an
absence. Examples of participation in academic activities representing attendance would be
participation in a class chat or discussion board on an academic topic, submission of a required
assignment, digital interaction with the professor on an academic topic and completion of a quiz
or exam. Administrative withdrawal results in removal from the course with a grade of “WA” or
WF” determined by the point in the term and the academic performance. Students should consult
the College catalog for complete details regarding withdrawals and the potential financial
implications of a withdrawal. 
Accommodations 
Molloy College makes a commitment to providing reasonable accommodations for any student
with a documented disability or chronic illness. Like so many things this semester, the need for
accommodations and the process for arranging them, may be altered by COVID-
19.  Students requiring accommodations in order to fully participate in this class are urged to
contact Disability Support Services (DSS/STEEP) at [email protected], as soon as possible.  
 
Zoom in the Classroom 
Zoom is a video conferencing tool where instructors and students can meet online at the same
time to interact in academic activities such as classroom lectures, student presentations, screen
sharing and discussions. Zoom is often utilized with online synchronous courses at Molloy. To
learn more about Zoom, visit the Zoom Help Center page. 
 
Minimizing Distractions During  Synchronous Online Class 
Zoom, or conferencing sessions, can be impacted by many different environmental or situational
variables. Here are some strategies and suggestions for minimizing such impact: 
 Students should mute their microphone when they are not speaking. 
 Consider using virtual backgrounds, which display the participant but mask the area behind them. 
 Students should not watch videos, listen to music, or use other applications (other than note taking apps) while
attending class. Doing so could not only distract the class but lead to a degradation in computer performance
that may affect the student viewer experience. 
 Student can use the chat feature in Zoom to communicate with the entire class and or the instructor but should
not be participating in one-to-one chats with their peers during class. 
 
Student Reminders and Etiquette 
Just as in an on-campus classroom, it is important to make the best virtual impression during a
Zoom meeting.
 You may be viewable, or heard, by the entire class during a Zoom session and should conduct yourself
accordingly. Classes may be recorded. 
 Dress as if you are in a classroom setting.
 Students are expected to uphold Molloy College’s Academic Honor Pledge. 
 Student recordings are only permitted if all participants are fully informed that the recording will be made and
all participants consent to being recorded. Please refer to the Molloy Student Handbook for more details.
 Abide by the Civility Policy found in the Molloy Student Handbook. 
 
Recording 
As a student enrolled in courses offered by Molloy College, Rockville Centre, New York, I
understand that classes may sometimes be audio or digitally captured for instructional purposes.
THESE RECORDINGS ARE INTENDED ONLY FOR EDUCATIONAL PURPOSES AND
WILL BE USED ONLY BY THE FACULTY AND STUDENTS ENROLLED IN THE
COURSE. PLEASE NOTIFY YOUR INSTRUCTOR BY EMAIL IF YOU DO NOT
CONSENT TO PARTICIPATION IN A DIGITAL RECORDING OF YOUR COURSE. 
If no student elects to withhold his/her consent prior to Sep. 8, 2020. digital recording of the
class (will/can) begin on Sep. 9, 2020. Any student who has not contacted the professor prior to
that date will be deemed to have consented to the recording. You may notify your professor by
email at any time if you choose to revoke your consent. 

THERE ARE NO EXTRA CREDIT PROJECTS, PAPERS OR

OTHER POINTS AWARDED. 'RE-TAKES' OF EXAMS OR
ASSIGNMENTS ARE NOT POSSIBLE. ALL SCORES
CONTRIBUTE TO THE FINAL GRADE [low scores are not
dropped].

The total numerical grade will be converted to the appropriate letter

grade according to the Molloy College catalog. Final averages are
calculated to the nearest tenth in accordance with the Molloy College
grading scale.
The Highest Standards of Academic Integrity are to be observed at
ALL TIMES. Academic infractions are subject to disciplinary
action. Particulars regarding this policy are found in the Student
Handbook.

Withdrawals: The last date to officially withdraw from the class is

December 11th. Each student is responsible for obtaining the proper
paperwork and all necessary signatures prior to giving the form to the
instructor on or before the above date if the student decides to withdraw
from the course. From the Molloy College Catalog: ”Nursing
students that withdraw from a science course with less than the
required C+ (77) grade will be given a WF.”

Email Accounts: Students are expected to have a Molloy College email

account and to check their Molloy email on a regular basis. Please be
aware that according to FERPA regulations any questions concerning
grades via email can only be answered from an email with a Molloy
College address.

Disability Support Services: Molloy College is in compliance with

section 504 of the Rehabilitation Act and offers aids and services for
post secondary students with disabilities. Comprehensive
documentation must be provided to the instructor for
acknowledgement of these services.

Computer Specifications for Use of Canvas:

Canvas will work properly on most modern (5 years old or newer) computers and
the mobile application will run on iOS and Android devices. In order to ensure the
best experience using Canvas, please use the latest version of any popular web
browser in conjunction with the latest versions of Flash and Java. Please note that
“Internet Explorer” may conflict with some content in Canvas. Firefox, Chrome or
Safari are more reliable options. Please make sure that you have access to a
computer that is compatible with Canvas. It is your responsibility to ensure access
to adequate equipment. For more information about supported browsers and
software, please visit: https://community.canvaslms.com/docs/DOC-1284

Canvas Support is accessed through the HELP feature in the lower left hand corner
of Canvas. You can either call Canvas at 844-408-6455 or use the online chat
feature and both services are available 24 hours 7 days a week.

Technology Support Services and The Information Commons are available to

support students’ technology needs. Technology Support Services is located in
Kellenberg 022 and can be reached via phone: 516.323.4800, email:
[email protected] or twitter: @molloyTSS.

Note: No work will be graded until the Student Agreement (found on a

subsequent page) has been signed and turned in to the professor

Student Agreement
I have read and understand all policies and
procedures outlined in the Course Outline for CHE
1120- Organic and Biological Chemistry and agree to
follow them in upholding the highest standards of
academic integrity as outlined in the Molloy College
Catalog

______________________________________________
(Name) (Signature) (Date)