-
Drug dependence and homeostasis | Processing the Environment | MCAT | Khan Academy
Created by Carole Yue.
Watch the next lesson: https://www.khanacademy.org/test-prep/mcat/processing-the-environment/drug-dependence/v/routes-of-drug-entry?utm_source=YT&utm_medium=Desc&utm_campaign=mcat
Missed the previous lesson? https://www.khanacademy.org/test-prep/mcat/processing-the-environment/drug-dependence/v/psychoactive-drugs-hallucinogens?utm_source=YT&utm_medium=Desc&utm_campaign=mcat
MCAT on Khan Academy: Go ahead and practice some passage-based questions!
About Khan Academy: Khan Academy offers practice exercises, instructional videos, and a personalized learning dashboard that empower learners to study at their own pace in and outside of the classroom. We tackle math, science, computer programming, history, art history, economics, and more. Our math missions guide learne...
published: 25 Jun 2014
-
Substance Abuse vs Substance Dependence (DSM-IV)
This video focuses on the basics of substances to prepare you for exams or boards. It is not a complete in-depth discussion, but a bare-bones essentials to maximize points on your next test.
***This classification has changed in the new DSM-V criteria. This information is a basic review of previous classification of abuse/dependence
published: 01 May 2014
-
What causes addiction, and why is it so hard to treat? - Judy Grisel
Take a look at the science of how addictive drugs affect your body and why substance addiction can be so difficult to treat.
--
As of 2021, more than 36 million people were estimated to be experiencing substance use disorder. This condition spans a spectrum of patterned drug use that causes issues in a person’s life, with substance addiction at the more severe end. Why are some people more susceptible to addiction, and why can it be so difficult to treat? Judy Grisel takes a look at how addictive drugs affect the body.
Lesson by Judy Grisel, directed by Gabriella Marsh.
Support Our Non-Profit Mission
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Support us on Patreon: http://bit.ly/TEDEdPatreon
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published: 19 Mar 2024
-
Medical Terminology Questions — Drug Abuse vs. Drug Dependence
Medical Terminology Questions — Drug Abuse vs. Drug Dependence https://www.cco.us/medical-terminology-anatomy-medical-coders-course
Drug abuse vs. drug dependence. Luna asks, "What kind of terminology might you find in a patient's record that would indicate abuse vs. dependence?" -- I had to do my little Google research, and for those that this is the first time on the call, the ongoing joke out there especially in Facebook land is that I always say "Google it." My niece told me, "That's what you're going to raise your kids, aren't you? You are going to tell them, 'Google it first.'" Yup! It's amazing what you can find, so don't be afraid to use Google for medical coding research. Just type it in and you'll be amazed at what you'll find. That's how I found this.
I'll go down to the foot...
published: 19 Apr 2013
-
Mechanism of Drug Addiction in the Brain, Animation.
This video is available for instant download licensing on AlilaMedicalMedia(dot)com
©Alila Medical Media. All rights reserved.
All images/videos by Alila Medical Media are for information purposes ONLY and are NOT intended to replace professional medical advice, diagnosis or treatment. Always seek the advice of a qualified healthcare provider with any questions you may have regarding a medical condition.
Addiction is a neurological disorder that affects the reward system in the brain. In a healthy person, the reward system reinforces important behaviors that are essential for survival such as eating, drinking, sex, and social interaction. For example, the reward system ensures that you reach for food when you are hungry, because you know that after eating you will feel good. In other wor...
published: 11 Sep 2014
-
Unlocking the Cure to Substance Use Disorder | Brad Finegood | TEDxUofW
With drug addiction and overdose rampant in Seattle, how can we change our mindset to make progress on this topic? Brad Finegood shares methods of how we can view addiction with intent to help. Brad Finegood is a Strategic Advisor in Public Health in Seattle & King County. He recently served as a co-chair of the King County Heroin and Prescription Opiate Task Force and was the Alcohol and Drug Coordinator for King County. He received his Bachelor’s Degree from Michigan State University and his Master’s Degree in Counseling with a Specialty in Alcohol and Drug Abuse from Western Michigan University. He has worked in the behavioral health field for 20 years. Most importantly he is the sibling and survivor of a younger sibling that passed away from an overdose. This talk was given at a T...
published: 08 Jul 2019
-
GBPH Substance Use Prevention Webinar 2024.06.27
published: 28 Jun 2024
-
Substance Dependence treatment and theory
published: 02 May 2013
-
Treatments and triggers for drug dependence | Processing the Environment | MCAT | Khan Academy
Visit us (http://www.khanacademy.org/science/healthcare-and-medicine) for health and medicine content or (http://www.khanacademy.org/test-prep/mcat) for MCAT related content. These videos do not provide medical advice and are for informational purposes only. The videos are not intended to be a substitute for professional medical advice, diagnosis or treatment. Always seek the advice of a qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read or seen in any Khan Academy video. Created by Arshya Vahabzadeh.
Watch the next lesson: https://www.khanacademy.org/test-prep/mcat/processing-the-environment/attention-language/v/divided-selective-attention-inattentio...
published: 25 Jun 2014
-
Understanding Substance Misuse, Abuse, Dependence and Addiction
Knowing the differences between the misuse and abuse of drugs or having a dependence on or an addiction to psychoactive substances like alcohol or pain relievers can help you communicate to others, particularly medical and mental health professionals, about your relationship with substances. These affiliated terms of substance use may seem to represent the same thing, and you'll find that some providers use a few of them interchangeably. But, if you want to understand the breadth of your relationship with psychotropic substances, the descriptions of these terms below may be informatively revealing.
Contact Wish Recovery today if you’re ready to get started on the road to recovery
888-212-8095
Wish Recovery is licensed by the State Department of Health Care Services.
Visit The State Depa...
published: 25 May 2021
3:18
Drug dependence and homeostasis | Processing the Environment | MCAT | Khan Academy
Created by Carole Yue.
Watch the next lesson: https://www.khanacademy.org/test-prep/mcat/processing-the-environment/drug-dependence/v/routes-of-drug-entry?utm_...
Created by Carole Yue.
Watch the next lesson: https://www.khanacademy.org/test-prep/mcat/processing-the-environment/drug-dependence/v/routes-of-drug-entry?utm_source=YT&utm_medium=Desc&utm_campaign=mcat
Missed the previous lesson? https://www.khanacademy.org/test-prep/mcat/processing-the-environment/drug-dependence/v/psychoactive-drugs-hallucinogens?utm_source=YT&utm_medium=Desc&utm_campaign=mcat
MCAT on Khan Academy: Go ahead and practice some passage-based questions!
About Khan Academy: Khan Academy offers practice exercises, instructional videos, and a personalized learning dashboard that empower learners to study at their own pace in and outside of the classroom. We tackle math, science, computer programming, history, art history, economics, and more. Our math missions guide learners from kindergarten to calculus using state-of-the-art, adaptive technology that identifies strengths and learning gaps. We've also partnered with institutions like NASA, The Museum of Modern Art, The California Academy of Sciences, and MIT to offer specialized content.
For free. For everyone. Forever. #YouCanLearnAnything
Subscribe to Khan Academy’s MCAT channel: https://www.youtube.com/channel/UCDkK5wqSuwDlJ3_nl3rgdiQ?sub_confirmation=1
Subscribe to Khan Academy: https://www.youtube.com/subscription_center?add_user=khanacademy
https://wn.com/Drug_Dependence_And_Homeostasis_|_Processing_The_Environment_|_Mcat_|_Khan_Academy
Created by Carole Yue.
Watch the next lesson: https://www.khanacademy.org/test-prep/mcat/processing-the-environment/drug-dependence/v/routes-of-drug-entry?utm_source=YT&utm_medium=Desc&utm_campaign=mcat
Missed the previous lesson? https://www.khanacademy.org/test-prep/mcat/processing-the-environment/drug-dependence/v/psychoactive-drugs-hallucinogens?utm_source=YT&utm_medium=Desc&utm_campaign=mcat
MCAT on Khan Academy: Go ahead and practice some passage-based questions!
About Khan Academy: Khan Academy offers practice exercises, instructional videos, and a personalized learning dashboard that empower learners to study at their own pace in and outside of the classroom. We tackle math, science, computer programming, history, art history, economics, and more. Our math missions guide learners from kindergarten to calculus using state-of-the-art, adaptive technology that identifies strengths and learning gaps. We've also partnered with institutions like NASA, The Museum of Modern Art, The California Academy of Sciences, and MIT to offer specialized content.
For free. For everyone. Forever. #YouCanLearnAnything
Subscribe to Khan Academy’s MCAT channel: https://www.youtube.com/channel/UCDkK5wqSuwDlJ3_nl3rgdiQ?sub_confirmation=1
Subscribe to Khan Academy: https://www.youtube.com/subscription_center?add_user=khanacademy
- published: 25 Jun 2014
- views: 102055
9:08
Substance Abuse vs Substance Dependence (DSM-IV)
This video focuses on the basics of substances to prepare you for exams or boards. It is not a complete in-depth discussion, but a bare-bones essentials to max...
This video focuses on the basics of substances to prepare you for exams or boards. It is not a complete in-depth discussion, but a bare-bones essentials to maximize points on your next test.
***This classification has changed in the new DSM-V criteria. This information is a basic review of previous classification of abuse/dependence
https://wn.com/Substance_Abuse_Vs_Substance_Dependence_(Dsm_Iv)
This video focuses on the basics of substances to prepare you for exams or boards. It is not a complete in-depth discussion, but a bare-bones essentials to maximize points on your next test.
***This classification has changed in the new DSM-V criteria. This information is a basic review of previous classification of abuse/dependence
- published: 01 May 2014
- views: 22857
5:43
What causes addiction, and why is it so hard to treat? - Judy Grisel
Take a look at the science of how addictive drugs affect your body and why substance addiction can be so difficult to treat.
--
As of 2021, more than 36 milli...
Take a look at the science of how addictive drugs affect your body and why substance addiction can be so difficult to treat.
--
As of 2021, more than 36 million people were estimated to be experiencing substance use disorder. This condition spans a spectrum of patterned drug use that causes issues in a person’s life, with substance addiction at the more severe end. Why are some people more susceptible to addiction, and why can it be so difficult to treat? Judy Grisel takes a look at how addictive drugs affect the body.
Lesson by Judy Grisel, directed by Gabriella Marsh.
Support Our Non-Profit Mission
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View full lesson: https://ed.ted.com/lessons/what-causes-addiction-and-why-is-it-so-hard-to-treat-judy-grisel
Dig deeper with additional resources: https://ed.ted.com/lessons/what-causes-addiction-and-why-is-it-so-hard-to-treat-judy-grisel/digdeeper
Animator's website: https://gabriella-marsh.com
Music: https://soundcloud.com/aim-music
----------------------------------------------
Thank you so much to our patrons for your support! Without you this video would not be possible! Barbara Smalley, Megan Douglas, Tim Leistikow, Ka-Hei Law, Hiroshi Uchiyama, Mark Morris, Misaki Sato, EdoKun, SookKwan Loong, Bev Millar, Lex Azevedo, Michael Aquilina, Jason A Saslow, Yansong Li, Cristóbal Moenne, Dawn Jordan, Prasanth Mathialagan, Samuel Doerle, David Rosario, Dominik Kugelmann - they-them, Siamak Hajizadeh, Ryohky Araya, Mayank Kaul, Christophe Dessalles, Heather Slater, Sandra Tersluisen, Zhexi Shan, Bárbara Nazaré, Andrea Feliz, Victor E Karhel, Sydney Evans, Latora, Noel Situ, emily lam, Sid, Niccolò Frassetto, Mana, I'm here because of Knowledge Fight Facebook group., Linda Freedman, Edgardo Cuellar, Jaspar Carmichael-Jack, Michael Burton, VIVIANA A GARCIA BESNE, The Vernon's, Olha Bahatiuk, Jesús Bíquez Talayero, Chels Raknrl, Sai Pranavi Jonnalagadda, Stuart Rice and Jing Chen.
https://wn.com/What_Causes_Addiction,_And_Why_Is_It_So_Hard_To_Treat_Judy_Grisel
Take a look at the science of how addictive drugs affect your body and why substance addiction can be so difficult to treat.
--
As of 2021, more than 36 million people were estimated to be experiencing substance use disorder. This condition spans a spectrum of patterned drug use that causes issues in a person’s life, with substance addiction at the more severe end. Why are some people more susceptible to addiction, and why can it be so difficult to treat? Judy Grisel takes a look at how addictive drugs affect the body.
Lesson by Judy Grisel, directed by Gabriella Marsh.
Support Our Non-Profit Mission
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Support us on Patreon: http://bit.ly/TEDEdPatreon
Check out our merch: http://bit.ly/TEDEDShop
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Keep Learning
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View full lesson: https://ed.ted.com/lessons/what-causes-addiction-and-why-is-it-so-hard-to-treat-judy-grisel
Dig deeper with additional resources: https://ed.ted.com/lessons/what-causes-addiction-and-why-is-it-so-hard-to-treat-judy-grisel/digdeeper
Animator's website: https://gabriella-marsh.com
Music: https://soundcloud.com/aim-music
----------------------------------------------
Thank you so much to our patrons for your support! Without you this video would not be possible! Barbara Smalley, Megan Douglas, Tim Leistikow, Ka-Hei Law, Hiroshi Uchiyama, Mark Morris, Misaki Sato, EdoKun, SookKwan Loong, Bev Millar, Lex Azevedo, Michael Aquilina, Jason A Saslow, Yansong Li, Cristóbal Moenne, Dawn Jordan, Prasanth Mathialagan, Samuel Doerle, David Rosario, Dominik Kugelmann - they-them, Siamak Hajizadeh, Ryohky Araya, Mayank Kaul, Christophe Dessalles, Heather Slater, Sandra Tersluisen, Zhexi Shan, Bárbara Nazaré, Andrea Feliz, Victor E Karhel, Sydney Evans, Latora, Noel Situ, emily lam, Sid, Niccolò Frassetto, Mana, I'm here because of Knowledge Fight Facebook group., Linda Freedman, Edgardo Cuellar, Jaspar Carmichael-Jack, Michael Burton, VIVIANA A GARCIA BESNE, The Vernon's, Olha Bahatiuk, Jesús Bíquez Talayero, Chels Raknrl, Sai Pranavi Jonnalagadda, Stuart Rice and Jing Chen.
- published: 19 Mar 2024
- views: 593749
4:51
Medical Terminology Questions — Drug Abuse vs. Drug Dependence
Medical Terminology Questions — Drug Abuse vs. Drug Dependence https://www.cco.us/medical-terminology-anatomy-medical-coders-course
Drug abuse vs. drug depende...
Medical Terminology Questions — Drug Abuse vs. Drug Dependence https://www.cco.us/medical-terminology-anatomy-medical-coders-course
Drug abuse vs. drug dependence. Luna asks, "What kind of terminology might you find in a patient's record that would indicate abuse vs. dependence?" -- I had to do my little Google research, and for those that this is the first time on the call, the ongoing joke out there especially in Facebook land is that I always say "Google it." My niece told me, "That's what you're going to raise your kids, aren't you? You are going to tell them, 'Google it first.'" Yup! It's amazing what you can find, so don't be afraid to use Google for medical coding research. Just type it in and you'll be amazed at what you'll find. That's how I found this.
I'll go down to the footnote so you can see where this came from first. It came from the American Psychiatric Association: Diagnostic and Statistical Manual of Mental Disorders: DSM-IV. That's an official manual that's used. We don't code from it, but it gives us the definitions that we do use for coding.
Before I go on, I just want to say as far as what indicates abuse vs. dependence, the physician should really be documenting one of those two words. You shouldn't have to piece it together, but to understand what's behind the difference.
Here we go: Substance abuse is defined as maladaptive pattern of substance use leading to clinically significant impairment or distress -- that's pretty much the same for abuse vs. dependence. Here's where the difference has come. They're going to have one (or more) of the following, occurring within a 12-month period: Recurrent substance use resulting in failure to fulfill major role obligations at work, school, or home. The second bullet: Recurrent substance use in situations in which is physical hazardous. Recurrent substance-related legal problems. Continued substance use despite having persistent or recurrent social or interpersonal problems.
They have a note here that the symptoms for abuse have never met the criteria for dependence -- so if they've ever met the criteria for dependence then that's what you should use. Now, according to this DSM-IV, a person can be abusing a substance or dependent on a substance but not both at the same time. That makes sense.
Here's a definition for dependence. So, everything was the same and they're going to have three or more of the following: Tolerance, as defined by either of the following: A need for markedly increased amounts of the substance to achieve intoxication or the desired effect. Withdrawal, they would go through with withdrawal if the substance was removed. The next bullet: The substance is often taken in larger amounts or over a longer period than intended. There's a persistent desire or unsuccessful efforts to cut down or control it. And then, a great deal of time is spent in activities necessary to obtain the substance, use it or recover from it. Important social, occupational, or recreational activities are given up or reduced because of it. The substance use is continued despite knowledge of having a persistent physical or psychological problem, like, cocaine use having that cocaine-induced depression or liver problems.
So that is the difference officially between abuse and dependence. So, dependence, three or more of those bullets and the abuse was one or more of these bullets.
This will be on the answer sheet, but again, if you just Google substance abuse vs. dependence, you will find pages like this. Again, coding wise, we really want the physician to tell us, is it drug abuse or drug dependence?
Click here to get more medical terminology questions, cpc exam tips, coding certification training, and ceu credits. https://www.cco.us/cco-monthly-newsletter
http://youtu.be/c7PdzyHZr2o
https://wn.com/Medical_Terminology_Questions_—_Drug_Abuse_Vs._Drug_Dependence
Medical Terminology Questions — Drug Abuse vs. Drug Dependence https://www.cco.us/medical-terminology-anatomy-medical-coders-course
Drug abuse vs. drug dependence. Luna asks, "What kind of terminology might you find in a patient's record that would indicate abuse vs. dependence?" -- I had to do my little Google research, and for those that this is the first time on the call, the ongoing joke out there especially in Facebook land is that I always say "Google it." My niece told me, "That's what you're going to raise your kids, aren't you? You are going to tell them, 'Google it first.'" Yup! It's amazing what you can find, so don't be afraid to use Google for medical coding research. Just type it in and you'll be amazed at what you'll find. That's how I found this.
I'll go down to the footnote so you can see where this came from first. It came from the American Psychiatric Association: Diagnostic and Statistical Manual of Mental Disorders: DSM-IV. That's an official manual that's used. We don't code from it, but it gives us the definitions that we do use for coding.
Before I go on, I just want to say as far as what indicates abuse vs. dependence, the physician should really be documenting one of those two words. You shouldn't have to piece it together, but to understand what's behind the difference.
Here we go: Substance abuse is defined as maladaptive pattern of substance use leading to clinically significant impairment or distress -- that's pretty much the same for abuse vs. dependence. Here's where the difference has come. They're going to have one (or more) of the following, occurring within a 12-month period: Recurrent substance use resulting in failure to fulfill major role obligations at work, school, or home. The second bullet: Recurrent substance use in situations in which is physical hazardous. Recurrent substance-related legal problems. Continued substance use despite having persistent or recurrent social or interpersonal problems.
They have a note here that the symptoms for abuse have never met the criteria for dependence -- so if they've ever met the criteria for dependence then that's what you should use. Now, according to this DSM-IV, a person can be abusing a substance or dependent on a substance but not both at the same time. That makes sense.
Here's a definition for dependence. So, everything was the same and they're going to have three or more of the following: Tolerance, as defined by either of the following: A need for markedly increased amounts of the substance to achieve intoxication or the desired effect. Withdrawal, they would go through with withdrawal if the substance was removed. The next bullet: The substance is often taken in larger amounts or over a longer period than intended. There's a persistent desire or unsuccessful efforts to cut down or control it. And then, a great deal of time is spent in activities necessary to obtain the substance, use it or recover from it. Important social, occupational, or recreational activities are given up or reduced because of it. The substance use is continued despite knowledge of having a persistent physical or psychological problem, like, cocaine use having that cocaine-induced depression or liver problems.
So that is the difference officially between abuse and dependence. So, dependence, three or more of those bullets and the abuse was one or more of these bullets.
This will be on the answer sheet, but again, if you just Google substance abuse vs. dependence, you will find pages like this. Again, coding wise, we really want the physician to tell us, is it drug abuse or drug dependence?
Click here to get more medical terminology questions, cpc exam tips, coding certification training, and ceu credits. https://www.cco.us/cco-monthly-newsletter
http://youtu.be/c7PdzyHZr2o
- published: 19 Apr 2013
- views: 1841
4:15
Mechanism of Drug Addiction in the Brain, Animation.
This video is available for instant download licensing on AlilaMedicalMedia(dot)com
©Alila Medical Media. All rights reserved.
All images/videos by Alila Medic...
This video is available for instant download licensing on AlilaMedicalMedia(dot)com
©Alila Medical Media. All rights reserved.
All images/videos by Alila Medical Media are for information purposes ONLY and are NOT intended to replace professional medical advice, diagnosis or treatment. Always seek the advice of a qualified healthcare provider with any questions you may have regarding a medical condition.
Addiction is a neurological disorder that affects the reward system in the brain. In a healthy person, the reward system reinforces important behaviors that are essential for survival such as eating, drinking, sex, and social interaction. For example, the reward system ensures that you reach for food when you are hungry, because you know that after eating you will feel good. In other words, it makes the activity of eating pleasurable and memorable, so you would want to do it again and again whenever you feel hungry. Drugs of abuse hijack this system, turning the person’s natural needs into drug needs.
The brain consists of billions of neurons, or nerve cells, which communicate via chemical messages, or neurotransmitters. When a neuron is sufficiently stimulated, an electrical impulse called an action potential is generated and travels down the axon to the nerve terminal. Here, it triggers the release of a neurotransmitter into the synaptic cleft - a space between neurons. The neurotransmitter then binds to a receptor on a neighboring neuron, generating a signal in it, thereby transmitting the information to that neuron.
The major reward pathways involve transmission of the neurotransmitter dopamine from the ventral tegmental area – the VTA - of the midbrain to the limbic system and the frontal cortex. Engaging in enjoyable activities generates action potentials in dopamine-producing neurons of the VTA. This causes dopamine release from the neurons into the synaptic space. Dopamine then binds to and stimulates dopamine-receptor on the receiving neuron. This stimulation by dopamine is believed to produce the pleasurable feelings or rewarding effect. Dopamine molecules are then removed from the synaptic space and transported back in to the transmitting neuron by a special protein called dopamine-transporter.
Most drugs of abuse increase the level of dopamine in the reward pathway. Some drugs such as alcohol, heroin, and nicotine indirectly excite the dopamine-producing neurons in the VTA so that they generate more action potentials. Cocaine acts at the nerve terminal. It binds to dopamine-transporter and blocks the re-uptake of dopamine. Methamphetamine – a psychostimulant – acts similarly to cocaine in blocking dopamine removal. In addition, it can enter the neuron, into the dopamine-containing vesicles where it triggers dopamine release even in the absence of action potentials.
Different drugs act different way but the common outcome is that dopamine builds-up in the synapse to a much greater amount than normal. This causes a continuous stimulation, maybe over-stimulation of receiving neurons and is responsible for prolonged and intense euphoria experienced by drug users. Repeated exposure to dopamine surges caused by drugs eventually de-sensitizes the reward system. The system is no longer responsive to everyday stimuli; the only thing that is rewarding is the drug. That is how drugs change the person’s life priority. After some time, even the drug loses its ability to reward and higher doses are required to achieve the rewarding effect. This ultimately leads to drug overdose.
https://wn.com/Mechanism_Of_Drug_Addiction_In_The_Brain,_Animation.
This video is available for instant download licensing on AlilaMedicalMedia(dot)com
©Alila Medical Media. All rights reserved.
All images/videos by Alila Medical Media are for information purposes ONLY and are NOT intended to replace professional medical advice, diagnosis or treatment. Always seek the advice of a qualified healthcare provider with any questions you may have regarding a medical condition.
Addiction is a neurological disorder that affects the reward system in the brain. In a healthy person, the reward system reinforces important behaviors that are essential for survival such as eating, drinking, sex, and social interaction. For example, the reward system ensures that you reach for food when you are hungry, because you know that after eating you will feel good. In other words, it makes the activity of eating pleasurable and memorable, so you would want to do it again and again whenever you feel hungry. Drugs of abuse hijack this system, turning the person’s natural needs into drug needs.
The brain consists of billions of neurons, or nerve cells, which communicate via chemical messages, or neurotransmitters. When a neuron is sufficiently stimulated, an electrical impulse called an action potential is generated and travels down the axon to the nerve terminal. Here, it triggers the release of a neurotransmitter into the synaptic cleft - a space between neurons. The neurotransmitter then binds to a receptor on a neighboring neuron, generating a signal in it, thereby transmitting the information to that neuron.
The major reward pathways involve transmission of the neurotransmitter dopamine from the ventral tegmental area – the VTA - of the midbrain to the limbic system and the frontal cortex. Engaging in enjoyable activities generates action potentials in dopamine-producing neurons of the VTA. This causes dopamine release from the neurons into the synaptic space. Dopamine then binds to and stimulates dopamine-receptor on the receiving neuron. This stimulation by dopamine is believed to produce the pleasurable feelings or rewarding effect. Dopamine molecules are then removed from the synaptic space and transported back in to the transmitting neuron by a special protein called dopamine-transporter.
Most drugs of abuse increase the level of dopamine in the reward pathway. Some drugs such as alcohol, heroin, and nicotine indirectly excite the dopamine-producing neurons in the VTA so that they generate more action potentials. Cocaine acts at the nerve terminal. It binds to dopamine-transporter and blocks the re-uptake of dopamine. Methamphetamine – a psychostimulant – acts similarly to cocaine in blocking dopamine removal. In addition, it can enter the neuron, into the dopamine-containing vesicles where it triggers dopamine release even in the absence of action potentials.
Different drugs act different way but the common outcome is that dopamine builds-up in the synapse to a much greater amount than normal. This causes a continuous stimulation, maybe over-stimulation of receiving neurons and is responsible for prolonged and intense euphoria experienced by drug users. Repeated exposure to dopamine surges caused by drugs eventually de-sensitizes the reward system. The system is no longer responsive to everyday stimuli; the only thing that is rewarding is the drug. That is how drugs change the person’s life priority. After some time, even the drug loses its ability to reward and higher doses are required to achieve the rewarding effect. This ultimately leads to drug overdose.
- published: 11 Sep 2014
- views: 1616563
14:18
Unlocking the Cure to Substance Use Disorder | Brad Finegood | TEDxUofW
With drug addiction and overdose rampant in Seattle, how can we change our mindset to make progress on this topic? Brad Finegood shares methods of how we can vi...
With drug addiction and overdose rampant in Seattle, how can we change our mindset to make progress on this topic? Brad Finegood shares methods of how we can view addiction with intent to help. Brad Finegood is a Strategic Advisor in Public Health in Seattle & King County. He recently served as a co-chair of the King County Heroin and Prescription Opiate Task Force and was the Alcohol and Drug Coordinator for King County. He received his Bachelor’s Degree from Michigan State University and his Master’s Degree in Counseling with a Specialty in Alcohol and Drug Abuse from Western Michigan University. He has worked in the behavioral health field for 20 years. Most importantly he is the sibling and survivor of a younger sibling that passed away from an overdose. This talk was given at a TEDx event using the TED conference format but independently organized by a local community. Learn more at https://www.ted.com/tedx
https://wn.com/Unlocking_The_Cure_To_Substance_Use_Disorder_|_Brad_Finegood_|_Tedxuofw
With drug addiction and overdose rampant in Seattle, how can we change our mindset to make progress on this topic? Brad Finegood shares methods of how we can view addiction with intent to help. Brad Finegood is a Strategic Advisor in Public Health in Seattle & King County. He recently served as a co-chair of the King County Heroin and Prescription Opiate Task Force and was the Alcohol and Drug Coordinator for King County. He received his Bachelor’s Degree from Michigan State University and his Master’s Degree in Counseling with a Specialty in Alcohol and Drug Abuse from Western Michigan University. He has worked in the behavioral health field for 20 years. Most importantly he is the sibling and survivor of a younger sibling that passed away from an overdose. This talk was given at a TEDx event using the TED conference format but independently organized by a local community. Learn more at https://www.ted.com/tedx
- published: 08 Jul 2019
- views: 141145
7:43
Treatments and triggers for drug dependence | Processing the Environment | MCAT | Khan Academy
Visit us (http://www.khanacademy.org/science/healthcare-and-medicine) for health and medicine content or (http://www.khanacademy.org/test-prep/mcat) for MCAT re...
Visit us (http://www.khanacademy.org/science/healthcare-and-medicine) for health and medicine content or (http://www.khanacademy.org/test-prep/mcat) for MCAT related content. These videos do not provide medical advice and are for informational purposes only. The videos are not intended to be a substitute for professional medical advice, diagnosis or treatment. Always seek the advice of a qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read or seen in any Khan Academy video. Created by Arshya Vahabzadeh.
Watch the next lesson: https://www.khanacademy.org/test-prep/mcat/processing-the-environment/attention-language/v/divided-selective-attention-inattentional-change-blindness?utm_source=YT&utm_medium=Desc&utm_campaign=mcat
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MCAT on Khan Academy: Go ahead and practice some passage-based questions!
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https://wn.com/Treatments_And_Triggers_For_Drug_Dependence_|_Processing_The_Environment_|_Mcat_|_Khan_Academy
Visit us (http://www.khanacademy.org/science/healthcare-and-medicine) for health and medicine content or (http://www.khanacademy.org/test-prep/mcat) for MCAT related content. These videos do not provide medical advice and are for informational purposes only. The videos are not intended to be a substitute for professional medical advice, diagnosis or treatment. Always seek the advice of a qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read or seen in any Khan Academy video. Created by Arshya Vahabzadeh.
Watch the next lesson: https://www.khanacademy.org/test-prep/mcat/processing-the-environment/attention-language/v/divided-selective-attention-inattentional-change-blindness?utm_source=YT&utm_medium=Desc&utm_campaign=mcat
Missed the previous lesson? https://www.khanacademy.org/test-prep/mcat/processing-the-environment/drug-dependence/v/substance-use-disorders?utm_source=YT&utm_medium=Desc&utm_campaign=mcat
MCAT on Khan Academy: Go ahead and practice some passage-based questions!
About Khan Academy: Khan Academy offers practice exercises, instructional videos, and a personalized learning dashboard that empower learners to study at their own pace in and outside of the classroom. We tackle math, science, computer programming, history, art history, economics, and more. Our math missions guide learners from kindergarten to calculus using state-of-the-art, adaptive technology that identifies strengths and learning gaps. We've also partnered with institutions like NASA, The Museum of Modern Art, The California Academy of Sciences, and MIT to offer specialized content.
For free. For everyone. Forever. #YouCanLearnAnything
Subscribe to Khan Academy’s MCAT channel: https://www.youtube.com/channel/UCDkK5wqSuwDlJ3_nl3rgdiQ?sub_confirmation=1
Subscribe to Khan Academy: https://www.youtube.com/subscription_center?add_user=khanacademy
- published: 25 Jun 2014
- views: 74500
2:10
Understanding Substance Misuse, Abuse, Dependence and Addiction
Knowing the differences between the misuse and abuse of drugs or having a dependence on or an addiction to psychoactive substances like alcohol or pain reliever...
Knowing the differences between the misuse and abuse of drugs or having a dependence on or an addiction to psychoactive substances like alcohol or pain relievers can help you communicate to others, particularly medical and mental health professionals, about your relationship with substances. These affiliated terms of substance use may seem to represent the same thing, and you'll find that some providers use a few of them interchangeably. But, if you want to understand the breadth of your relationship with psychotropic substances, the descriptions of these terms below may be informatively revealing.
Contact Wish Recovery today if you’re ready to get started on the road to recovery
888-212-8095
Wish Recovery is licensed by the State Department of Health Care Services.
Visit The State Department of Health Care Services website for licensing information: https://shorturl.at/jtAU0
https://wn.com/Understanding_Substance_Misuse,_Abuse,_Dependence_And_Addiction
Knowing the differences between the misuse and abuse of drugs or having a dependence on or an addiction to psychoactive substances like alcohol or pain relievers can help you communicate to others, particularly medical and mental health professionals, about your relationship with substances. These affiliated terms of substance use may seem to represent the same thing, and you'll find that some providers use a few of them interchangeably. But, if you want to understand the breadth of your relationship with psychotropic substances, the descriptions of these terms below may be informatively revealing.
Contact Wish Recovery today if you’re ready to get started on the road to recovery
888-212-8095
Wish Recovery is licensed by the State Department of Health Care Services.
Visit The State Department of Health Care Services website for licensing information: https://shorturl.at/jtAU0
- published: 25 May 2021
- views: 326535