'+pages+''); $('.stream > div:odd').addClass('bgr_color'); updateHeight('#history'); }); window.activateTabArea = ensure(function(tab, areas){ var parsed = false; var parts = (areas || '').split('/'); window.fsonload = $.inArray('fs', parts) >= 0; if(fsonload){ parts.splice(parts.indexOf('fs'), 1); } var replayMode = false; if($.inArray('replay', parts)>=0){ replayMode = 'replay'; } var noSoundMode = false; if($.inArray('nosound', parts)>=0){ noSoundMode = 'nosound'; } if($.inArray('ns', parts)>=0){ noSoundMode = 'ns'; } var previewMode = null; if($.inArray('p', parts)>=0){ previewMode = 'p'; } if($.inArray('preview', parts)>=0){ previewMode = 'preview'; } if($.inArray('repeat', parts)>=0){ replayMode = 'repeat'; } if($.inArray('r', parts)>=0 || $.inArray('ro', parts)>=0){ replayMode = 'r'; } if(replayMode){ parts.splice(parts.indexOf(replayMode), 1); } if(noSoundMode){ parts.splice(parts.indexOf(noSoundMode), 1); } if(previewMode){ parts.splice(parts.indexOf(previewMode), 1); } if(previewMode){ if(!parts.length){ parts = ['1-14', '999:59']; } } var area = parts[0]; if(tab == 'history' && false){ var page = parseInt(area || '1') || 1; $.ajax({ url: 'https://login.wn.com/recent/json/?pp='+history_pp+'&skip='+history_pp*(page-1), dataType: 'jsonp', success: function(response){ $ensure(function(){ renderHistory(response, page); }); } }); return true; } if(tab == 'global_history' && false){ var page = parseInt(area || '1') || 1; globalHistory.fetchStream(page, '', function(){ updateHeight('#global_history'); }); return true; } if(tab == 'my_playlists' && false){ var page = parseInt(area || '1') || 1; myPlaylists.fetchStream(page, '', function(){ updateHeight('#my_playlists'); }); return true; } if(tab == 'my_videos' && false){ var page = parseInt(area || '1') || 1; myVideos.fetchStream(page, '', function(){ updateHeight('#my_videos'); }); return true; } if(tab == 'related_sites' && areas && matchPosition(areas)){ var seconds = parsePosition(areas); scrollRelated(seconds); return false; } if(matchPosition(area) || matchAction(area)){ parts.unshift('1'); area = parts[0]; } if(tab == 'expand' && area && area.match(/\d+/)) { var num = parseInt(area); if(num < 100){ //FIX ME. 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playShouldStart = null; } }; function loadMoreVideos(playerId, vp, start, finish, callback){ var playlistInfo = playlists[playerId-1]; if(playlistInfo.loading >= finish) return; playlistInfo.loading = finish; $.ajax({ url: '/api/upge/cheetah-photo-search/query_videos2', dataType: 'json', data: { query: playlistInfo.query, orderby: playlistInfo.orderby, start: start, count: finish-start }, success: function(response){ var pl = vp.getPlaylist().slice(0); pl.push.apply(pl, response); vp.setPlaylist(pl); callback(); } }); } if(parts.length == 1 && matchDash(parts[0])){ var pl = vp.getActualPlaylist(); var vids = parseDash(parts[0]); parts = []; for(var i = 0; i < vids.length; i++){ playQueue.push({ 'video': pl[vids[i]-1], 'start': 0, 'stop': null }) } if(vids.length){ if(vids[vids.length-1]-1>=pl.length){ loadMoreVideos(playerId, vp, pl.length, vids[vids.length-1], function(){ if(fsonload){ activateTabArea(tab, parts[0]+'/fs'); }else{ activateTabArea(tab, parts[0]); } var pls = vp.getPlaylist(); vp.playFromPlaylist(pls[pls.length-1]); vp.playVideo(); scrollToPlaylistPosition(vp); }); return true; } } if(playQueue){ playQueueUpdate(); vp.playVideo(); parsed = true; playShouldStart = 0; } } if(previewMode){ var vids = []; var dur = 0; var pl = vp.getActualPlaylist(); area = parts[0]; if(parts.length == 1 && matchPosition(parts[0])){ vids = parseDash('1-'+pl.length); dur = parsePosition(parts[0]); parts = []; }else if(parts.length == 1 && matchDash(parts[0])){ vids = parseDash(parts[0]); dur = parsePosition("999:59"); parts = []; } if(parts.length == 2 && matchDash(parts[0]) && matchPosition(parts[1])){ vids = parseDash(parts[0]); dur = parsePosition(parts[1]); parts = []; } for(var i = 0; i < vids.length; i++){ playQueue.push({ 'video': pl[vids[i]-1], 'start': 0, 'stop': dur }) } if(playQueue){ playQueueUpdate(); vp.playVideo(); parsed = true; } } if(parts.length>1){ for(var i = 0; i < parts.length; i++){ var sel = findMatchingVideo(vp, parts[i]); if(sel){ playQueue.push({ 'video': sel, 'start': 0, 'stop': null }) } } if(playQueue){ playQueueUpdate(); 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if(vp.getCurrentVideo() == playQueue[playQueuePosition].video){ playQueueAdvancePosition(); }else{ playShouldStart = null; } } }, 500); vp.playerContainer.bind('videoplayer.player.statechange', function(e, state){ if(state == 'ended'){ // advance to the next video playQueueAdvancePosition(); } }); vp.playerContainer.bind('videoplayer.player.readychange', function(e, state){ if(state){ updateVolumeState(); if(playShouldStart !== null){ vp.seekTo(playShouldStart); playShouldStart = null; }else{ playShouldStop = null; // someone started other video, stop playing from playQueue } } if(fsonload) { triggerFullscreen(playerId); fsonload = false; } }); } } else if(tab.match(/^wiki\d+$/)){ if(firstTimeActivate){ load_wiki($('#'+tab), function(){ if(area){ var areaNode = $('#'+area); if(areaNode.length>0){ $('html, body').scrollTop(areaNode.offset().top + 10); return true; } } }); } } return parsed; }) window.activateTab = ensure(function(tab, area){ window.activeArea = null; if(tab == 'import_videos'){ if(area){ import_videos(area); }else{ start_import(); } return true; } if(tab == 'chat'){ update_chat_position($('.chat').eq(0)); window.activeArea = 'chat'; jQuery('.tabtrigger').offscreentabs('activateTab', 'chat'); return true; } if(tab in rev_names){ tab = rev_names[tab]; } if(tab.match(':')){ return false; } var sup = $('ul li a[id=#'+tab+']'); if(sup && sup.length>0){ window.activeArea = area; sup.first().click(); if(!window.activateTabArea(tab, area)){ window.activeArea = null; } window.activeArea = null; return true; }else{ var have_tabs = $('#playlist_menu li').length; if(tab.match(/^playlists?\d+$/)){ var to_add = +tab.substring(8).replace(/^s/,'')-have_tabs; if(to_add>0 && have_tabs){ add_more_videos(to_add); return true; } } } return false; }); window.currentPath = ensure(function(){ return window.lastHistory.replace(basepath, '').split('?')[0]; }); window.main_tab = window.main_tab || 'videos'; window.addHistory = ensure(function(path){ if(window.console && console.log) console.log("Adding to history: "+path); if(window.history && history.replaceState && document.location.hostname.match(/^(youtube\.)?(\w{2,3}\.)?wn\.com$/)){ if(path == main_tab || path == main_tab+'/' || path == '' || path == '/') { path = basepath; } else if( path.match('^'+main_tab+'/') ){ path = basepath + '/' + path.replace(main_tab+'/', '').replace('--','/'); } else { path = basepath + '/' + path.replace('--','/'); } if(document.location.search){ path += document.location.search; } if(window.lastHistory) { history.pushState(null, null, path); } else if(window.lastHistory != path){ history.replaceState(null, null, path); window.lastHistory = path; } } else{ path = path.replace('--','/'); if(path == main_tab || path == main_tab+'/' || path == '' || path == '/') { path = ''; } if(window.lastHistory != '/'+path){ window.location.hash = path? '/'+path : ''; window.lastHistory = '/'+path; } } }); $('.tabtrigger li a').live('click', ensure(function() { var tab = $(this).attr('id'); if(tab.substring(0,1) == '#'){ var name = tab.substring(1); if(name in menu_names){ name = menu_names[name][0]; } realTab = rev_names[name]; $('#'+realTab).show(); if(window.console && console.log) console.log("Triggering tab: "+name+(window.activeArea?" activeArea="+window.activeArea:'')); var path = name; if(window.activeArea){ path = path + '/' + window.activeArea; } if(tab.match(/#playlist\d+/) || tab.match(/#details\d+/)){ $('.multiple-playlists').show(); $('.related_playlist').show(); $('.longest_videos_playlist').show(); }else { $('.multiple-playlists').hide(); $('.related_playlist').hide(); $('.longest_videos_playlist').hide(); } // start the related script only when the tab is on screen showing if (tab.match(/related_sites/)) { if (mc) { mc.startCredits(); } } window.activeTab = realTab; addHistory(path); setTimeout(ensure(function(){ if(tab.match(/language--/)){ $('.tabtrigger').offscreentabs('activateTab', 'language'); } if(tab.match(/weather/)) { $('.tabtrigger').offscreentabs('activateTab', 'weather'); loadContinent(); } updateMenus(tab); updateHeight(); }), 10); } return false; })); }); -->

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• Givinostat

Givinostat

Givinostat (INN) or gavinostat (originally ITF2357) is a histone deacetylase inhibitor with potential anti-inflammatory, anti-angiogenic, and antineoplastic activities. It is a hydroxamate used in the form of its hydrochloride.

Givinostat is in numerous phase II clinical trials (including for relapsed leukemias and myelomas), and has been granted orphan drug designation in the European Union for the treatment of systemic juvenile idiopathic arthritis and polycythaemia vera.

ITF2357 was discovered at Italfarmaco of Milan, Italy. It was patented in 1997 and first described in the scientific literature in 2005.

Adverse effects

In clinical trials of givinostat as a salvage therapy for advanced Hodgkin's lymphoma, the most common adverse reactions were fatigue (seen in 50% of participants), mild diarrhea or abdominal pain (40% of participants), moderate thrombocytopenia (decreased platelet counts, seen in one third of patients), and mild leukopenia (a decrease in white blood cell levels, seen in 30% of patients). One-fifth of patients experienced prolongation of the QT interval, a measure of electrical conduction in the heart, severe enough to warrant temporary suspension of treatment.

Read more

This page contains text from Wikipedia, the Free Encyclopedia - https://wn.com/Givinostat

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Email this Page Play all in Full Screen Show More Related Videos

• 

  Distrofia di Duchenne, i dati sulla molecola italiana givinostat

  Intervista al Prof. Pier Lorenzo Puri, Professore di pediatria, Università della California a Los Angeles (UCLA)

  published: 21 Feb 2016
• 

  Webinar - Risultati dello studio clinico con Givinostat nella BMD

  Registrazione del webinar del 27 ottobre 2021, nel quale si è parlato dei risultati dello studio clinico di fase 2 con givinostat nella distrofia muscolare di Becker. Ad illustrare i risultati emersi dallo studio e a rispondere alle domande di pazienti e famiglie, il Prof. Giacomo Comi, responsabile del trial presso il Policlinico di Milano.

  published: 08 Nov 2021
• 

  Webinar: Italfarmaco Provides Givinostat Update [April 2020]

  On April 22, 2020, Italfarmaco joined Parent Project Muscular Dystrophy for a webinar to update the community about Italfarmaco's development of Givinostat and the recent results of the futility analysis of the enrolling Phase 3 confirmatory study in Duchenne muscular dystrophy.

  published: 27 Apr 2020
• 

  [Webinar] Italfarmaco Provides Givinostat Update - January 2018

  Italfarmaco joined PPMD for a webinar on January 24, 2018 to update the Duchenne community about Italfarmaco's development of Givinostat and currently enrolling Phase 3 confirmatory study in Duchenne muscular dystrophy.

  published: 30 Jan 2018
• 

  [Webinar] Italfarmaco Provides Givinostat Update - March 2019

  Italfarmaco joined PPMD for a webinar on March 27, 2019 to update the community about Italfarmaco's development of Givinostat and currently enrolling Phase 3 confirmatory study in Duchenne muscular dystrophy.

  published: 02 Apr 2019
• 

  Trial Update: Givinostat - Italfarmaco [PPMD's 2017 Connect Conference]

  Paolo Bettica, MD, PhD (Italfarmaco) presents at PPMD's Annual Connect Conference on June 30, 2017.

  published: 17 Jul 2017
• 

  GC17836 ITF2357 (Givinostat)

  Protocol, Chemical Properties, Background of ITF2357 (Givinostat) https://www.glpbio.com/itf2357-givinostat.html

  published: 18 Jul 2019

developed with YouTube

3:10

Distrofia di Duchenne, i dati sulla molecola italiana givinostat

• Order: Reorder
• Duration: 3:10
• Uploaded Date: 21 Feb 2016
• views: 542

Intervista al Prof. Pier Lorenzo Puri, Professore di pediatria, Università della California a Los Angeles (UCLA)

Intervista al Prof. Pier Lorenzo Puri, Professore di pediatria, Università della California a Los Angeles (UCLA)

https://wn.com/Distrofia_Di_Duchenne,_I_Dati_Sulla_Molecola_Italiana_Givinostat

Intervista al Prof. Pier Lorenzo Puri, Professore di pediatria, Università della California a Los Angeles (UCLA)

• published: 21 Feb 2016
• views: 542

1:25:48

Webinar - Risultati dello studio clinico con Givinostat nella BMD

• Order: Reorder
• Duration: 1:25:48
• Uploaded Date: 08 Nov 2021
• views: 288

Registrazione del webinar del 27 ottobre 2021, nel quale si è parlato dei risultati dello studio clinico di fase 2 con givinostat nella distrofia muscolare di B...

Registrazione del webinar del 27 ottobre 2021, nel quale si è parlato dei risultati dello studio clinico di fase 2 con givinostat nella distrofia muscolare di Becker. Ad illustrare i risultati emersi dallo studio e a rispondere alle domande di pazienti e famiglie, il Prof. Giacomo Comi, responsabile del trial presso il Policlinico di Milano.

https://wn.com/Webinar_Risultati_Dello_Studio_Clinico_Con_Givinostat_Nella_Bmd

Registrazione del webinar del 27 ottobre 2021, nel quale si è parlato dei risultati dello studio clinico di fase 2 con givinostat nella distrofia muscolare di Becker. Ad illustrare i risultati emersi dallo studio e a rispondere alle domande di pazienti e famiglie, il Prof. Giacomo Comi, responsabile del trial presso il Policlinico di Milano.

• published: 08 Nov 2021
• views: 288

54:07

Webinar: Italfarmaco Provides Givinostat Update [April 2020]

• Order: Reorder
• Duration: 54:07
• Uploaded Date: 27 Apr 2020
• views: 597

On April 22, 2020, Italfarmaco joined Parent Project Muscular Dystrophy for a webinar to update the community about Italfarmaco's development of Givinostat and ...

On April 22, 2020, Italfarmaco joined Parent Project Muscular Dystrophy for a webinar to update the community about Italfarmaco's development of Givinostat and the recent results of the futility analysis of the enrolling Phase 3 confirmatory study in Duchenne muscular dystrophy.

https://wn.com/Webinar_Italfarmaco_Provides_Givinostat_Update_April_2020

On April 22, 2020, Italfarmaco joined Parent Project Muscular Dystrophy for a webinar to update the community about Italfarmaco's development of Givinostat and the recent results of the futility analysis of the enrolling Phase 3 confirmatory study in Duchenne muscular dystrophy.

• published: 27 Apr 2020
• views: 597

53:56

[Webinar] Italfarmaco Provides Givinostat Update - January 2018

• Order: Reorder
• Duration: 53:56
• Uploaded Date: 30 Jan 2018
• views: 1572

Italfarmaco joined PPMD for a webinar on January 24, 2018 to update the Duchenne community about Italfarmaco's development of Givinostat and currently enrolling...

Italfarmaco joined PPMD for a webinar on January 24, 2018 to update the Duchenne community about Italfarmaco's development of Givinostat and currently enrolling Phase 3 confirmatory study in Duchenne muscular dystrophy.

https://wn.com/Webinar_Italfarmaco_Provides_Givinostat_Update_January_2018

Italfarmaco joined PPMD for a webinar on January 24, 2018 to update the Duchenne community about Italfarmaco's development of Givinostat and currently enrolling Phase 3 confirmatory study in Duchenne muscular dystrophy.

• published: 30 Jan 2018
• views: 1572

48:56

[Webinar] Italfarmaco Provides Givinostat Update - March 2019

• Order: Reorder
• Duration: 48:56
• Uploaded Date: 02 Apr 2019
• views: 941

Italfarmaco joined PPMD for a webinar on March 27, 2019 to update the community about Italfarmaco's development of Givinostat and currently enrolling Phase 3 co...

Italfarmaco joined PPMD for a webinar on March 27, 2019 to update the community about Italfarmaco's development of Givinostat and currently enrolling Phase 3 confirmatory study in Duchenne muscular dystrophy.

https://wn.com/Webinar_Italfarmaco_Provides_Givinostat_Update_March_2019

Italfarmaco joined PPMD for a webinar on March 27, 2019 to update the community about Italfarmaco's development of Givinostat and currently enrolling Phase 3 confirmatory study in Duchenne muscular dystrophy.

• published: 02 Apr 2019
• views: 941

13:01

Trial Update: Givinostat - Italfarmaco [PPMD's 2017 Connect Conference]

• Order: Reorder
• Duration: 13:01
• Uploaded Date: 17 Jul 2017
• views: 753

Paolo Bettica, MD, PhD (Italfarmaco) presents at PPMD's Annual Connect Conference on June 30, 2017.

Paolo Bettica, MD, PhD (Italfarmaco) presents at PPMD's Annual Connect Conference on June 30, 2017.

https://wn.com/Trial_Update_Givinostat_Italfarmaco_Ppmd's_2017_Connect_Conference

Paolo Bettica, MD, PhD (Italfarmaco) presents at PPMD's Annual Connect Conference on June 30, 2017.

• published: 17 Jul 2017
• views: 753

0:22

GC17836 ITF2357 (Givinostat)

• Order: Reorder
• Duration: 0:22
• Uploaded Date: 18 Jul 2019
• views: 13

Protocol, Chemical Properties, Background of ITF2357 (Givinostat) https://www.glpbio.com/itf2357-givinostat.html

Protocol, Chemical Properties, Background of ITF2357 (Givinostat) https://www.glpbio.com/itf2357-givinostat.html

https://wn.com/Gc17836_Itf2357_(Givinostat)

Protocol, Chemical Properties, Background of ITF2357 (Givinostat) https://www.glpbio.com/itf2357-givinostat.html

• published: 18 Jul 2019
• views: 13

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PLAYLIST TIME:

back

• Most Related
• Most Recent
• Most Popular
• Top Rated

• expand screen to full width
• repeat playlist
• shuffle
• replay video
• clear playlist restore
• images list

developed with YouTube

PLAYLIST TIME:

3:10

Distrofia di Duchenne, i dati sulla molecola italiana givinostat

Intervista al Prof. Pier Lorenzo Puri, Professore di pediatria, Università della Californi...

published: 21 Feb 2016

Play in Full Screen

Distrofia di Duchenne, i dati sulla molecola italiana givinostat

Distrofia di Duchenne, i dati sulla molecola italiana givinostat

• Report rights infringement
• published: 21 Feb 2016
• views: 542

Intervista al Prof. Pier Lorenzo Puri, Professore di pediatria, Università della California a Los Angeles (UCLA)

• Show More

1:25:48

Webinar - Risultati dello studio clinico con Givinostat nella BMD

Registrazione del webinar del 27 ottobre 2021, nel quale si è parlato dei risultati dello ...

published: 08 Nov 2021

Play in Full Screen

Webinar - Risultati dello studio clinico con Givinostat nella BMD

Webinar - Risultati dello studio clinico con Givinostat nella BMD

• Report rights infringement
• published: 08 Nov 2021
• views: 288

Registrazione del webinar del 27 ottobre 2021, nel quale si è parlato dei risultati dello studio clinico di fase 2 con givinostat nella distrofia muscolare di Becker. Ad illustrare i risultati emersi dallo studio e a rispondere alle domande di pazienti e famiglie, il Prof. Giacomo Comi, responsabile del trial presso il Policlinico di Milano.

• Show More

54:07

Webinar: Italfarmaco Provides Givinostat Update [April 2020]

On April 22, 2020, Italfarmaco joined Parent Project Muscular Dystrophy for a webinar to u...

published: 27 Apr 2020

Play in Full Screen

Webinar: Italfarmaco Provides Givinostat Update [April 2020]

Webinar: Italfarmaco Provides Givinostat Update [April 2020]

• Report rights infringement
• published: 27 Apr 2020
• views: 597

On April 22, 2020, Italfarmaco joined Parent Project Muscular Dystrophy for a webinar to update the community about Italfarmaco's development of Givinostat and the recent results of the futility analysis of the enrolling Phase 3 confirmatory study in Duchenne muscular dystrophy.

• Show More

53:56

[Webinar] Italfarmaco Provides Givinostat Update - January 2018

Italfarmaco joined PPMD for a webinar on January 24, 2018 to update the Duchenne community...

published: 30 Jan 2018

Play in Full Screen

[Webinar] Italfarmaco Provides Givinostat Update - January 2018

[Webinar] Italfarmaco Provides Givinostat Update - January 2018

• Report rights infringement
• published: 30 Jan 2018
• views: 1572

Italfarmaco joined PPMD for a webinar on January 24, 2018 to update the Duchenne community about Italfarmaco's development of Givinostat and currently enrolling Phase 3 confirmatory study in Duchenne muscular dystrophy.

• Show More

48:56

[Webinar] Italfarmaco Provides Givinostat Update - March 2019

Italfarmaco joined PPMD for a webinar on March 27, 2019 to update the community about Ital...

published: 02 Apr 2019

Play in Full Screen

[Webinar] Italfarmaco Provides Givinostat Update - March 2019

[Webinar] Italfarmaco Provides Givinostat Update - March 2019

• Report rights infringement
• published: 02 Apr 2019
• views: 941

Italfarmaco joined PPMD for a webinar on March 27, 2019 to update the community about Italfarmaco's development of Givinostat and currently enrolling Phase 3 confirmatory study in Duchenne muscular dystrophy.

• Show More

13:01

Trial Update: Givinostat - Italfarmaco [PPMD's 2017 Connect Conference]

Paolo Bettica, MD, PhD (Italfarmaco) presents at PPMD's Annual Connect Conference on June...

published: 17 Jul 2017

Play in Full Screen

Trial Update: Givinostat - Italfarmaco [PPMD's 2017 Connect Conference]

Trial Update: Givinostat - Italfarmaco [PPMD's 2017 Connect Conference]

• Report rights infringement
• published: 17 Jul 2017
• views: 753

Paolo Bettica, MD, PhD (Italfarmaco) presents at PPMD's Annual Connect Conference on June 30, 2017.

• Show More

0:22

GC17836 ITF2357 (Givinostat)

Protocol, Chemical Properties, Background of ITF2357 (Givinostat) https://www.glpbio.com/i...

published: 18 Jul 2019

Play in Full Screen

GC17836 ITF2357 (Givinostat)

GC17836 ITF2357 (Givinostat)

• Report rights infringement
• published: 18 Jul 2019
• views: 13

Protocol, Chemical Properties, Background of ITF2357 (Givinostat) https://www.glpbio.com/itf2357-givinostat.html

• Show More

Givinostat

Givinostat (INN) or gavinostat (originally ITF2357) is a histone deacetylase inhibitor with potential anti-inflammatory, anti-angiogenic, and antineoplastic activities. It is a hydroxamate used in the form of its hydrochloride.

Givinostat is in numerous phase II clinical trials (including for relapsed leukemias and myelomas), and has been granted orphan drug designation in the European Union for the treatment of systemic juvenile idiopathic arthritis and polycythaemia vera.

ITF2357 was discovered at Italfarmaco of Milan, Italy. It was patented in 1997 and first described in the scientific literature in 2005.

Adverse effects

In clinical trials of givinostat as a salvage therapy for advanced Hodgkin's lymphoma, the most common adverse reactions were fatigue (seen in 50% of participants), mild diarrhea or abdominal pain (40% of participants), moderate thrombocytopenia (decreased platelet counts, seen in one third of patients), and mild leukopenia (a decrease in white blood cell levels, seen in 30% of patients). One-fifth of patients experienced prolongation of the QT interval, a measure of electrical conduction in the heart, severe enough to warrant temporary suspension of treatment.

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This page contains text from Wikipedia, the Free Encyclopedia - https://wn.com/Givinostat

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Latest News for: givinostat

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ITF Therapeutics LLC Announces U.S. Commercial Availability of DUVYZAT™ (givinostat) for Treatment of Patients With ...

The Essex Reporter 26 Jul 2024

First nonsteroidal treatment approved for patients six years of age and older with DMD regardless of genetic mutation now available in the U.S ....

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ITF Therapeutics LLC Announces U.S. Commercial Availability of DUVYZAT™ (givinostat) for Treatment of Patients With Duchenne Muscular Dystrophy

PR Newswire 25 Jul 2024

commercial launch of DUVYZAT™ (givinostat), a histone deacetylase inhibitor, for the treatment of patients six years of age and older with Duchenne muscular dystrophy (DMD) ... About DUVYZAT™ (givinostat).

Edit

Muscular Dystrophy Association’S Funding Of Foundational Research Leads To New FDA Approved Treatment Duvyzat (Givinostat) ...

MENA FN 22 Mar 2024

(MENAFN - GlobeNewsWire - Nasdaq) New York, March 21, 2024 (GLOBE NEWSWIRE) -- The Muscular Dystrophy Association's funding of foundational research leads to new drug approval by the US Food and ... .

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PPMD Applauds FDA For Approval Of DUVYZATTM (Givinostat) For Duchenne Patients Ages Six Years And Older

MENA FN 22 Mar 2024

(MENAFN - PR Newswire) WASHINGTON, March 21, 2024 /PRNewswire/ --Parent Project Muscular Dystrophy (PPMD) , a nonprofit organization leading the fight to end Duchenne muscular dystrophy (Duchenne) ... .

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Italfarmaco Receives FDA Approval for Duvyzat™ (givinostat) in Duchenne Muscular Dystrophy

The Associated Press 22 Mar 2024

Food and Drug Administration (FDA) has approved Duvyzat™ ...

Edit

PPMD Applauds FDA for Approval of DUVYZAT™ (Givinostat) for Duchenne Patients Ages Six Years and Older

The Associated Press 22 Mar 2024

... to approve DUVYZAT™(givinostat) a histone deacetylase (HD .

Edit

Results from Italfarmaco Pivotal Phase 3 EPIDYS Study of Givinostat in Duchenne Muscular Dystrophy (DMD) ...

The Associated Press 19 Mar 2024

announced today that the full results from the Company’s ...

Edit

Italfarmaco Group Announces New PDUFA Date for Givinostat DMD NDA

Business Wire 29 Nov 2023

Food and Drug Administration (FDA) has extended the review process of the New Drug Application (NDA) ...

Edit

Italfarmaco Group Receives EMA Validation of Marketing Authorization Application for Givinostat in Duchenne Muscular Dystrophy

Business Wire 05 Sep 2023

... trial which tested Givinostat, a histone deacetylase (HDAC) inhibitor, in patients with DMD.

Edit

Italfarmaco Group Completes FDA Submission of New Drug Application for Givinostat in Duchenne Muscular Dystrophy ...

Business Wire 29 Jun 2023

... completed its filing review and accepted the company’s New Drug Application (NDA) for Givinostat.

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Italfarmaco Group Announces Positive Topline Data from Phase 3 Trial Showing Beneficial Effect of Givinostat ...

Business Wire 26 Jun 2022

The study compared Givinostat to placebo and met the primary endpoint (change .

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