Fat mass and obesity-associated protein also known as alpha-ketoglutarate-dependent dioxygenase FTO is an enzyme that in humans is encoded by the FTOgene located on chromosome 16. As one homolog in the AlkB family proteins, it is the first mRNA demethylase that has been identified. Certain variants of the FTO gene appear to be correlated with obesity in humans.
Function
The amino acidsequence of the transcribed FTO protein shows high similarity with the enzyme AlkB which oxidatively demethylatesDNA. Recombinant FTO protein was first discovered to catalyze demethylation of 3-methylthymine in single-stranded DNA, and 3-methyluridine in single-stranded RNA, with low efficiency. The nucleosideN6-methyladenosine, an abundant modification in RNA, was then found to be a major substrate of FTO. The FTO gene expression was also found to be significantly upregulated in the hypothalamus of rats after food deprivation and strongly negatively correlated with the expression of orexigenic galanin-like peptide which is involved in the stimulation of food intake.
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published: 26 May 2020
QUICKEST FTO TUTORIAL | How to solve the Face-Turning Octahedron
DID YOU KNOW if you shop at SpeedCubeShop.com and use discount code: NOBLE at checkout you can save LOTS OF MONEY and support my channel! :)
FTO I used in this video: https://speedcubeshop.com/products/diansheng-fto-magnetic?_pos=2&_sid=11a62edbd&_ss=r&variant=41114332332145
Shout out to Ben Puzzles for creating a more in depth tutorial which I based my tutorial on: https://youtu.be/tYeV8LvqVDY?si=kFvgrBG-q6amBT7e
Follow me on Instagram! - https://www.instagram.com/noblecubes/
published: 25 Jul 2024
Blvd Bizz Ft 1Hunnid - FTO (Official Video)
Blvd BIzz Ft 1Hunnid - FTO (Official Music Video )
Follow Blvd Bizz ⬇️
Instagram - https://www.instagram.com/blvdbizz/?hl=en
Twitter- https://twitter.com/blvdbizz
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For More Music ⬇️ :
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Spotify - https://open.spotify.com/artist/5iESzq4XdJXus218beNwep
Soundcloud - https://soundcloud.com/blvd-bizz-538073562
published: 24 Aug 2021
Rell Vert x Bloodyhound Lil Jeff - F.T.O. (Official Music Video)
published: 06 Mar 2024
Mdot 59 x Coe Wiki - FTO (WGN Performance)
published: 11 Oct 2024
I spent 24 hours with the DianSheng FTO.
I spend an entire day trying out, learning new techniques, and getting faster on the exciting new stickerless, magnetic Face-Turning Octahedron speedcube by DianSheng!
Buy it here ($18): https://www.thecubicle.com/products/diansheng-fto?p=HJMGVPebP
Use discount code "z3cubing" for 5% off everything at TheCubicle.com! https://www.thecubicle.com/?p=HJMGVPebP (Affiliate Link/Code)
Bencisco FTO Tutorial: https://youtu.be/tYeV8LvqVDY
Benpuzzles' channel: https://www.youtube.com/@benpuzzles
Outro Music: "Ruby" by Jim Yosef and Alex Skrindo [NCS Release]
https://youtu.be/Np-Y8ClGgRk
Merch: https://teespring.com/stores/Z3Cubing
0:00 - Unboxing
0:53 - 12 PM - First Impressions
2:10 - 1 PM - Mechanism & Setup
3:06 - 2 PM - New Method
3:37 - 3 PM - Solving Overview
5:21 - 4 PM - Speedsolving ...
published: 20 Jul 2024
I Tried Solving the Diansheng FTO with NO HELP
Purchase the Diansheng FTO: https://www.thecubicle.com/products/diansheng-fto
The Diansheng face-turning octahedron is one of the most anticipated puzzles this year so far. It's the first mass-produced magnetic FTO that we've seen, which is a big leap for the FTO community. However, none of us have solved an FTO before, so Jesse figured this would be a good chance to stretch those puzzle solving muscles and try to figure out how to solve the puzzle with no tutorials or walkthroughs.
------------------------------------------------------------------------------------------------------
Want to learn from some of the best competitive speedcubers? Check out Cubing.gg!
https://www.cubing.gg/
Twitch: https://www.twitch.tv/thecubiclestream
TikTok: https://www.tiktok.com/@thecubicle.official
I...
published: 08 Jul 2024
I've fallen in love with a NEW puzzle (it's the FTO)
ORDER THE NEW DIANSHENG FTO WITH DISCOUNT CODE "TINGMAN! ➡️ https://www.thecubicle.com/products/diansheng-fto?p=PVtdt-ZRf
How to Solve a Face Turning Octahedron (Bencisco method) https://www.youtube.com/watch?v=tYeV8LvqVDY
Ben's FTO tutorial playlist https://www.youtube.com/playlist?list=PLmsIIxL8dGWubJDG6wD_KHaRxbxFhmXyA
#FTOforWCA
🎉 Use discount code "TINGMAN" to get yourself the best speedcubes! ➡️ https://bit.ly/cubicle-tingman
🎉Community chats, cubing livestreams and exclusive videos on the Tingman Patreon! 😍 Check it out here ➡️ http://patreon.com/tingman
💛 PATREON GOLD TIER MEMBERS (thank you!)
Anthony Jiang
curiousNic
FireStriker
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Joey Day
ND Chang
Judy Lin
Peter Preston
chadzdnato
Henry Samuel
Scott King
Phil Yu
parkebra
teachercubed
⭐️ Want a pe...
published: 21 Jun 2024
Tap in for FTO with PW, LIVE at 7:30pm!
Tap in for FTO with PW, LIVE at 7:30pm!
published: 03 Dec 2024
Will this be the next OFFICIAL WCA Puzzle? | Diansheng FTO Face turning Octahedron
DID YOU KNOW if you shop at SpeedCubeShop.com and use discount code: NOBLE at checkout you can save LOTS OF MONEY and support my channel! :)
FTO I used in this video: https://speedcubeshop.com/products/diansheng-fto-magnetic?_pos=2&_sid=11a62edbd&_ss=r&variant=41114332332145
Shout out to Ben Puzzles for creating a more in depth tutorial which I based my tutorial on: https://youtu.be/tYeV8LvqVDY?si=kFvgrBG-q6amBT7e
Follow me on Instagram! - https://www.instagram.com/noblecubes/
DID YOU KNOW if you shop at SpeedCubeShop.com and use discount code: NOBLE at checkout you can save LOTS OF MONEY and support my channel! :)
FTO I used in this...
DID YOU KNOW if you shop at SpeedCubeShop.com and use discount code: NOBLE at checkout you can save LOTS OF MONEY and support my channel! :)
FTO I used in this video: https://speedcubeshop.com/products/diansheng-fto-magnetic?_pos=2&_sid=11a62edbd&_ss=r&variant=41114332332145
Shout out to Ben Puzzles for creating a more in depth tutorial which I based my tutorial on: https://youtu.be/tYeV8LvqVDY?si=kFvgrBG-q6amBT7e
Follow me on Instagram! - https://www.instagram.com/noblecubes/
DID YOU KNOW if you shop at SpeedCubeShop.com and use discount code: NOBLE at checkout you can save LOTS OF MONEY and support my channel! :)
FTO I used in this video: https://speedcubeshop.com/products/diansheng-fto-magnetic?_pos=2&_sid=11a62edbd&_ss=r&variant=41114332332145
Shout out to Ben Puzzles for creating a more in depth tutorial which I based my tutorial on: https://youtu.be/tYeV8LvqVDY?si=kFvgrBG-q6amBT7e
Follow me on Instagram! - https://www.instagram.com/noblecubes/
Blvd BIzz Ft 1Hunnid - FTO (Official Music Video )
Follow Blvd Bizz ⬇️
Instagram - https://www.instagram.com/blvdbizz/?hl=en
Twitter- https://twitter.com/b...
Blvd BIzz Ft 1Hunnid - FTO (Official Music Video )
Follow Blvd Bizz ⬇️
Instagram - https://www.instagram.com/blvdbizz/?hl=en
Twitter- https://twitter.com/blvdbizz
Follow 1Hunnid ⬇️
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For More Music ⬇️ :
Apple Music - https://music.apple.com/ca/artist/blvd-bizz/1499899019
Spotify - https://open.spotify.com/artist/5iESzq4XdJXus218beNwep
Soundcloud - https://soundcloud.com/blvd-bizz-538073562
Blvd BIzz Ft 1Hunnid - FTO (Official Music Video )
Follow Blvd Bizz ⬇️
Instagram - https://www.instagram.com/blvdbizz/?hl=en
Twitter- https://twitter.com/blvdbizz
Follow 1Hunnid ⬇️
Instagram - https://www.instagram.com/1hunnid.ggg/?hl=en
For More Music ⬇️ :
Apple Music - https://music.apple.com/ca/artist/blvd-bizz/1499899019
Spotify - https://open.spotify.com/artist/5iESzq4XdJXus218beNwep
Soundcloud - https://soundcloud.com/blvd-bizz-538073562
I spend an entire day trying out, learning new techniques, and getting faster on the exciting new stickerless, magnetic Face-Turning Octahedron speedcube by Dia...
I spend an entire day trying out, learning new techniques, and getting faster on the exciting new stickerless, magnetic Face-Turning Octahedron speedcube by DianSheng!
Buy it here ($18): https://www.thecubicle.com/products/diansheng-fto?p=HJMGVPebP
Use discount code "z3cubing" for 5% off everything at TheCubicle.com! https://www.thecubicle.com/?p=HJMGVPebP (Affiliate Link/Code)
Bencisco FTO Tutorial: https://youtu.be/tYeV8LvqVDY
Benpuzzles' channel: https://www.youtube.com/@benpuzzles
Outro Music: "Ruby" by Jim Yosef and Alex Skrindo [NCS Release]
https://youtu.be/Np-Y8ClGgRk
Merch: https://teespring.com/stores/Z3Cubing
0:00 - Unboxing
0:53 - 12 PM - First Impressions
2:10 - 1 PM - Mechanism & Setup
3:06 - 2 PM - New Method
3:37 - 3 PM - Solving Overview
5:21 - 4 PM - Speedsolving #1
5:43 - 6 PM - New Tricks
6:37 - 8 PM - Sleep
7:02 - 7 AM - Practice
7:22 - 8 AM - Running lol
7:34 - 9 AM - Speedsolving #2
8:06 - 11 AM - Final Thoughts
8:51 - PB Solve!
#RubiksCube #cubing #Z3Cubing
I spend an entire day trying out, learning new techniques, and getting faster on the exciting new stickerless, magnetic Face-Turning Octahedron speedcube by DianSheng!
Buy it here ($18): https://www.thecubicle.com/products/diansheng-fto?p=HJMGVPebP
Use discount code "z3cubing" for 5% off everything at TheCubicle.com! https://www.thecubicle.com/?p=HJMGVPebP (Affiliate Link/Code)
Bencisco FTO Tutorial: https://youtu.be/tYeV8LvqVDY
Benpuzzles' channel: https://www.youtube.com/@benpuzzles
Outro Music: "Ruby" by Jim Yosef and Alex Skrindo [NCS Release]
https://youtu.be/Np-Y8ClGgRk
Merch: https://teespring.com/stores/Z3Cubing
0:00 - Unboxing
0:53 - 12 PM - First Impressions
2:10 - 1 PM - Mechanism & Setup
3:06 - 2 PM - New Method
3:37 - 3 PM - Solving Overview
5:21 - 4 PM - Speedsolving #1
5:43 - 6 PM - New Tricks
6:37 - 8 PM - Sleep
7:02 - 7 AM - Practice
7:22 - 8 AM - Running lol
7:34 - 9 AM - Speedsolving #2
8:06 - 11 AM - Final Thoughts
8:51 - PB Solve!
#RubiksCube #cubing #Z3Cubing
Purchase the Diansheng FTO: https://www.thecubicle.com/products/diansheng-fto
The Diansheng face-turning octahedron is one of the most anticipated puzzles this...
Purchase the Diansheng FTO: https://www.thecubicle.com/products/diansheng-fto
The Diansheng face-turning octahedron is one of the most anticipated puzzles this year so far. It's the first mass-produced magnetic FTO that we've seen, which is a big leap for the FTO community. However, none of us have solved an FTO before, so Jesse figured this would be a good chance to stretch those puzzle solving muscles and try to figure out how to solve the puzzle with no tutorials or walkthroughs.
------------------------------------------------------------------------------------------------------
Want to learn from some of the best competitive speedcubers? Check out Cubing.gg!
https://www.cubing.gg/
Twitch: https://www.twitch.tv/thecubiclestream
TikTok: https://www.tiktok.com/@thecubicle.official
Instagram: https://www.instagram.com/thecubicleofficial
Facebook: https://www.facebook.com/TheCubicleOfficial
Join our Discord community: https://discord.gg/JX9HXxwAmd
Purchase the Diansheng FTO: https://www.thecubicle.com/products/diansheng-fto
The Diansheng face-turning octahedron is one of the most anticipated puzzles this year so far. It's the first mass-produced magnetic FTO that we've seen, which is a big leap for the FTO community. However, none of us have solved an FTO before, so Jesse figured this would be a good chance to stretch those puzzle solving muscles and try to figure out how to solve the puzzle with no tutorials or walkthroughs.
------------------------------------------------------------------------------------------------------
Want to learn from some of the best competitive speedcubers? Check out Cubing.gg!
https://www.cubing.gg/
Twitch: https://www.twitch.tv/thecubiclestream
TikTok: https://www.tiktok.com/@thecubicle.official
Instagram: https://www.instagram.com/thecubicleofficial
Facebook: https://www.facebook.com/TheCubicleOfficial
Join our Discord community: https://discord.gg/JX9HXxwAmd
ORDER THE NEW DIANSHENG FTO WITH DISCOUNT CODE "TINGMAN! ➡️ https://www.thecubicle.com/products/diansheng-fto?p=PVtdt-ZRf
How to Solve a Face Turning Octahedro...
ORDER THE NEW DIANSHENG FTO WITH DISCOUNT CODE "TINGMAN! ➡️ https://www.thecubicle.com/products/diansheng-fto?p=PVtdt-ZRf
How to Solve a Face Turning Octahedron (Bencisco method) https://www.youtube.com/watch?v=tYeV8LvqVDY
Ben's FTO tutorial playlist https://www.youtube.com/playlist?list=PLmsIIxL8dGWubJDG6wD_KHaRxbxFhmXyA
#FTOforWCA
🎉 Use discount code "TINGMAN" to get yourself the best speedcubes! ➡️ https://bit.ly/cubicle-tingman
🎉Community chats, cubing livestreams and exclusive videos on the Tingman Patreon! 😍 Check it out here ➡️ http://patreon.com/tingman
💛 PATREON GOLD TIER MEMBERS (thank you!)
Anthony Jiang
curiousNic
FireStriker
Matilda Fero
solver5K
carlo :D
Joey Day
ND Chang
Judy Lin
Peter Preston
chadzdnato
Henry Samuel
Scott King
Phil Yu
parkebra
teachercubed
⭐️ Want a personalised message? I'm on Cameo! 🎤 https://www.cameo.com/tingman
⭐️ Follow us on Instagram! 📷 https://www.instagram.com/tingmanofficial
⭐️ TINGMAN MERCH 👕 http://tingman.store
FAVs (Frequently Asked Videos)
🌀 MY RUBIK'S CUBE TUTORIAL https://youtu.be/F68LxcmBw4E
🌀 CUBE COMPETITION VLOGS https://youtube.com/playlist?list=PLR60SzdZnJIbSTuQOtPlssY7HLrM72mdE
🌀 HUGE CUBE UNBOXINGS https://youtube.com/playlist?list=PLR60SzdZnJIY2b_F51f3sQTKvXW2q4YN8
🌀 FUN FAMILY CUBING VIDEOS https://youtube.com/playlist?list=PLR60SzdZnJIYre7rlSn6YhUA0_M5shDQu
ORDER THE NEW DIANSHENG FTO WITH DISCOUNT CODE "TINGMAN! ➡️ https://www.thecubicle.com/products/diansheng-fto?p=PVtdt-ZRf
How to Solve a Face Turning Octahedron (Bencisco method) https://www.youtube.com/watch?v=tYeV8LvqVDY
Ben's FTO tutorial playlist https://www.youtube.com/playlist?list=PLmsIIxL8dGWubJDG6wD_KHaRxbxFhmXyA
#FTOforWCA
🎉 Use discount code "TINGMAN" to get yourself the best speedcubes! ➡️ https://bit.ly/cubicle-tingman
🎉Community chats, cubing livestreams and exclusive videos on the Tingman Patreon! 😍 Check it out here ➡️ http://patreon.com/tingman
💛 PATREON GOLD TIER MEMBERS (thank you!)
Anthony Jiang
curiousNic
FireStriker
Matilda Fero
solver5K
carlo :D
Joey Day
ND Chang
Judy Lin
Peter Preston
chadzdnato
Henry Samuel
Scott King
Phil Yu
parkebra
teachercubed
⭐️ Want a personalised message? I'm on Cameo! 🎤 https://www.cameo.com/tingman
⭐️ Follow us on Instagram! 📷 https://www.instagram.com/tingmanofficial
⭐️ TINGMAN MERCH 👕 http://tingman.store
FAVs (Frequently Asked Videos)
🌀 MY RUBIK'S CUBE TUTORIAL https://youtu.be/F68LxcmBw4E
🌀 CUBE COMPETITION VLOGS https://youtube.com/playlist?list=PLR60SzdZnJIbSTuQOtPlssY7HLrM72mdE
🌀 HUGE CUBE UNBOXINGS https://youtube.com/playlist?list=PLR60SzdZnJIY2b_F51f3sQTKvXW2q4YN8
🌀 FUN FAMILY CUBING VIDEOS https://youtube.com/playlist?list=PLR60SzdZnJIYre7rlSn6YhUA0_M5shDQu
DID YOU KNOW if you shop at SpeedCubeShop.com and use discount code: NOBLE at checkout you can save LOTS OF MONEY and support my channel! :)
FTO I used in this...
DID YOU KNOW if you shop at SpeedCubeShop.com and use discount code: NOBLE at checkout you can save LOTS OF MONEY and support my channel! :)
FTO I used in this video: https://speedcubeshop.com/products/diansheng-fto-magnetic?_pos=2&_sid=11a62edbd&_ss=r&variant=41114332332145
Shout out to Ben Puzzles for creating a more in depth tutorial which I based my tutorial on: https://youtu.be/tYeV8LvqVDY?si=kFvgrBG-q6amBT7e
Follow me on Instagram! - https://www.instagram.com/noblecubes/
DID YOU KNOW if you shop at SpeedCubeShop.com and use discount code: NOBLE at checkout you can save LOTS OF MONEY and support my channel! :)
FTO I used in this video: https://speedcubeshop.com/products/diansheng-fto-magnetic?_pos=2&_sid=11a62edbd&_ss=r&variant=41114332332145
Shout out to Ben Puzzles for creating a more in depth tutorial which I based my tutorial on: https://youtu.be/tYeV8LvqVDY?si=kFvgrBG-q6amBT7e
Follow me on Instagram! - https://www.instagram.com/noblecubes/
DID YOU KNOW if you shop at SpeedCubeShop.com and use discount code: NOBLE at checkout you can save LOTS OF MONEY and support my channel! :)
FTO I used in this video: https://speedcubeshop.com/products/diansheng-fto-magnetic?_pos=2&_sid=11a62edbd&_ss=r&variant=41114332332145
Shout out to Ben Puzzles for creating a more in depth tutorial which I based my tutorial on: https://youtu.be/tYeV8LvqVDY?si=kFvgrBG-q6amBT7e
Follow me on Instagram! - https://www.instagram.com/noblecubes/
Blvd BIzz Ft 1Hunnid - FTO (Official Music Video )
Follow Blvd Bizz ⬇️
Instagram - https://www.instagram.com/blvdbizz/?hl=en
Twitter- https://twitter.com/blvdbizz
Follow 1Hunnid ⬇️
Instagram - https://www.instagram.com/1hunnid.ggg/?hl=en
For More Music ⬇️ :
Apple Music - https://music.apple.com/ca/artist/blvd-bizz/1499899019
Spotify - https://open.spotify.com/artist/5iESzq4XdJXus218beNwep
Soundcloud - https://soundcloud.com/blvd-bizz-538073562
I spend an entire day trying out, learning new techniques, and getting faster on the exciting new stickerless, magnetic Face-Turning Octahedron speedcube by DianSheng!
Buy it here ($18): https://www.thecubicle.com/products/diansheng-fto?p=HJMGVPebP
Use discount code "z3cubing" for 5% off everything at TheCubicle.com! https://www.thecubicle.com/?p=HJMGVPebP (Affiliate Link/Code)
Bencisco FTO Tutorial: https://youtu.be/tYeV8LvqVDY
Benpuzzles' channel: https://www.youtube.com/@benpuzzles
Outro Music: "Ruby" by Jim Yosef and Alex Skrindo [NCS Release]
https://youtu.be/Np-Y8ClGgRk
Merch: https://teespring.com/stores/Z3Cubing
0:00 - Unboxing
0:53 - 12 PM - First Impressions
2:10 - 1 PM - Mechanism & Setup
3:06 - 2 PM - New Method
3:37 - 3 PM - Solving Overview
5:21 - 4 PM - Speedsolving #1
5:43 - 6 PM - New Tricks
6:37 - 8 PM - Sleep
7:02 - 7 AM - Practice
7:22 - 8 AM - Running lol
7:34 - 9 AM - Speedsolving #2
8:06 - 11 AM - Final Thoughts
8:51 - PB Solve!
#RubiksCube #cubing #Z3Cubing
Purchase the Diansheng FTO: https://www.thecubicle.com/products/diansheng-fto
The Diansheng face-turning octahedron is one of the most anticipated puzzles this year so far. It's the first mass-produced magnetic FTO that we've seen, which is a big leap for the FTO community. However, none of us have solved an FTO before, so Jesse figured this would be a good chance to stretch those puzzle solving muscles and try to figure out how to solve the puzzle with no tutorials or walkthroughs.
------------------------------------------------------------------------------------------------------
Want to learn from some of the best competitive speedcubers? Check out Cubing.gg!
https://www.cubing.gg/
Twitch: https://www.twitch.tv/thecubiclestream
TikTok: https://www.tiktok.com/@thecubicle.official
Instagram: https://www.instagram.com/thecubicleofficial
Facebook: https://www.facebook.com/TheCubicleOfficial
Join our Discord community: https://discord.gg/JX9HXxwAmd
ORDER THE NEW DIANSHENG FTO WITH DISCOUNT CODE "TINGMAN! ➡️ https://www.thecubicle.com/products/diansheng-fto?p=PVtdt-ZRf
How to Solve a Face Turning Octahedron (Bencisco method) https://www.youtube.com/watch?v=tYeV8LvqVDY
Ben's FTO tutorial playlist https://www.youtube.com/playlist?list=PLmsIIxL8dGWubJDG6wD_KHaRxbxFhmXyA
#FTOforWCA
🎉 Use discount code "TINGMAN" to get yourself the best speedcubes! ➡️ https://bit.ly/cubicle-tingman
🎉Community chats, cubing livestreams and exclusive videos on the Tingman Patreon! 😍 Check it out here ➡️ http://patreon.com/tingman
💛 PATREON GOLD TIER MEMBERS (thank you!)
Anthony Jiang
curiousNic
FireStriker
Matilda Fero
solver5K
carlo :D
Joey Day
ND Chang
Judy Lin
Peter Preston
chadzdnato
Henry Samuel
Scott King
Phil Yu
parkebra
teachercubed
⭐️ Want a personalised message? I'm on Cameo! 🎤 https://www.cameo.com/tingman
⭐️ Follow us on Instagram! 📷 https://www.instagram.com/tingmanofficial
⭐️ TINGMAN MERCH 👕 http://tingman.store
FAVs (Frequently Asked Videos)
🌀 MY RUBIK'S CUBE TUTORIAL https://youtu.be/F68LxcmBw4E
🌀 CUBE COMPETITION VLOGS https://youtube.com/playlist?list=PLR60SzdZnJIbSTuQOtPlssY7HLrM72mdE
🌀 HUGE CUBE UNBOXINGS https://youtube.com/playlist?list=PLR60SzdZnJIY2b_F51f3sQTKvXW2q4YN8
🌀 FUN FAMILY CUBING VIDEOS https://youtube.com/playlist?list=PLR60SzdZnJIYre7rlSn6YhUA0_M5shDQu
DID YOU KNOW if you shop at SpeedCubeShop.com and use discount code: NOBLE at checkout you can save LOTS OF MONEY and support my channel! :)
FTO I used in this video: https://speedcubeshop.com/products/diansheng-fto-magnetic?_pos=2&_sid=11a62edbd&_ss=r&variant=41114332332145
Shout out to Ben Puzzles for creating a more in depth tutorial which I based my tutorial on: https://youtu.be/tYeV8LvqVDY?si=kFvgrBG-q6amBT7e
Follow me on Instagram! - https://www.instagram.com/noblecubes/
Fat mass and obesity-associated protein also known as alpha-ketoglutarate-dependent dioxygenase FTO is an enzyme that in humans is encoded by the FTOgene located on chromosome 16. As one homolog in the AlkB family proteins, it is the first mRNA demethylase that has been identified. Certain variants of the FTO gene appear to be correlated with obesity in humans.
Function
The amino acidsequence of the transcribed FTO protein shows high similarity with the enzyme AlkB which oxidatively demethylatesDNA. Recombinant FTO protein was first discovered to catalyze demethylation of 3-methylthymine in single-stranded DNA, and 3-methyluridine in single-stranded RNA, with low efficiency. The nucleosideN6-methyladenosine, an abundant modification in RNA, was then found to be a major substrate of FTO. The FTO gene expression was also found to be significantly upregulated in the hypothalamus of rats after food deprivation and strongly negatively correlated with the expression of orexigenic galanin-like peptide which is involved in the stimulation of food intake.
R. Crowell - Jolly Cheeks Music - BMI I looked for trouble and I found it son, Straight down the barrel of a lawman's gun. I'd try to run but I don't think I can, You make one move and you're a dead man, friend. Ain't livin' long like this, Can't live at all like this, can I baby? He slipped the handcuffs on behind my back, Then left me freezin' on a steel rail rack. Can't sleep at all in the jailhouse baby, Ain't livin' long like this. Grew up in Houston on the wayside drive, Son of a car hop in some all nite dive. Dad drove a stock car to an early death, All I remember was a drunk man's breathe. Ain't livin' long like this, Can't live at all like this, can I baby? We know the story how the wheel goes 'round, Don't let 'em take you to the man downtown, They got 'em all in the jailhouse baby. Ain't livin' long like this, Can't live at all like this, can I baby? Ah take it! {Erik - Solo} I live for Angel, she's a road house queen, Makes Texas Ruby look like Sandra Dee. I want to love her but I don't know how, I'm at the bottom of a jailhouse now. Ain't livin' long like this, Can't live at all like this, can I baby? You know the story 'bout the jailhouse rock, Go on and do it, but just don't get caught. They got 'em all in the jailhouse baby. Oh, ain't livin' long like this. Oh no!
FTO employees in ATS will work in the office full-time, 5 days a week according to this schedule.January 6, 2025 ... FTO employees should continue to be present in the office 3 to 5 days per week.
...LahoreChamberMian Abuzar Shah also joined as guest of honour.</p><p>Dr Asif Jah further highlighted the role of the FTO in resolving taxpayers' complaints efficiently and impartially.
Federal Tax Ombudsman (FTO) Dr Asif Mahmood Jah can be seen ... Federal Tax Ombudsman (FTO) Dr Asif Mahmood Jah has said that tax-related issues of the Association of Builders and Developers (ABAD) will be resolved on a priority basis.
</p><p>By prioritizing transparency and accountability in the tax administration, the FTO aims to foster trust between the taxpayers and tax authorities.
The Federal Tax Ombudsman (FTO) has found that medical colleges and universities secured undue and unauthorised tax exemptions, causing multibillion-rupees losses to the national exchequer ... the FTO ...
Michael Best's Clients to Benefit from Expedited and AccurateFTOAnalysis... For years, the firm relied on an in-house technology solution for managing FTO assessment processes, a method that, while effective, became cumbersome to maintain and update.
</p><p>The FTO encourages all taxpayers to visit the desk for any filing assistance.</p><p>FTO secretariat remains committed to facilitating taxpayers and looks forward to resolving their tax related issues.</p> .
TrainedFBR officials will be available to offer hands-on support to tax filers.</p><p>Please note that queries will only be addressed in person at the FTOSecretariat in Islamabad—no assistance will be provided via phone calls.