Exonuclease 1 is an enzyme that in humans is encoded by the EXO1gene.
This gene encodes a protein with 5' to 3' exonuclease activity as well as an RNase H activity (endonuclease activity cleaving RNA on DNA/RNA hybrid). It is similar to the Saccharomyces cerevisiae protein Exo1 which interacts with Msh2 and which is involved in DNA mismatch repair and homologous recombination. Alternative splicing of this gene results in three transcript variants encoding two different isoforms.
Meiosis
ExoI is essential for meiotic progression through metaphase I in the budding yeast Saccharomyces cerevisiae and in mouse.
Recombination during meiosis is often initiated by a DNA double-strand break (DSB) as illustrated in the accompanying diagram. During recombination, sections of DNA at the 5' ends of the break are cut away in a process called resection. In the strand invasion step that follows, an overhanging 3' end of the broken DNA molecule "invades" the DNA of an homologous chromosome that is not broken, forming a displacement loop (D-loop). After strand invasion, the further sequence of events may follow either of two main pathways leading to a crossover (CO) or a non-crossover (NCO) recombinant (see Genetic recombination and Homologous recombination). The pathway leading to a CO involves a double Holliday junction (DHJ) intermediate. Holliday junctions need to be resolved for CO recombination to be completed.
Best! is a greatest hits compilation by the 1990s pop band Jellyfish. The album was released in 2006 and featured twenty tracks. Eight of the tracks were non-album while the other twelve consisted of songs pulled from the band's two (and only) albums, Bellybutton and Spilt Milk. The song "Ignorance is Bliss" was taken from a Nintendo games compilation entitled "Nintendo: White Knuckle Scorin'" and is inspired by the video game Super Mario World. The song "No Matter What" is a live cover of a Badfinger song.
Best is the first Japanese compilation album and sixth overall album release by Mika Nakashima. It contains 14 songs. Two new re-recordings were made: one of her first single, 'Stars,' and the other of 'Amazing Grace (05),' the latter of which was included in a Suntory commercial for Freixnet Champagne and made as a radio-only single to promote the album in Japan.
A music video compilation, also called 'BEST,' was released in Japan and Southeast Asia in December 2005. It contains the music videos for all of Mika's first 18 singles – from 'Stars' to 'Glamorous Sky' – and the promotional videos for 'Amazing Grace (05)' and a previously unreleased live recording of the song 'Blood.'
Best debuted at #1 in the Japan Oricon 200 Album Chart when it was released, selling 480,097 copies in its first week – bettering the first-week sales of her first album, True. It was the #5 album of 2006.
Since its release, BEST has sold 1,204,996 copies. Therefore, BEST is the second best-selling album in Mika's career only to Love, outselling True by over 30,000 copies.
The wine region is located primarily on a plateau that is sheltered on three sides by the granite mountain ranges of Serra da Estrela, Serra do Caramulo and Serra da Nave. This helps the area maintain its temperate climate away from the effects of the nearby Atlantic Ocean. The region experiences abundant rainfall in the winter months and long, warm dry summers leading up to harvest. The region's vineyards are planted on sandy well-drained soil on top of granite rock.
Dao are single-edged Chinese swords, primarily used for slashing and chopping. The most common form is also known as the Chinese sabre, although those with wider blades are sometimes referred to as Chinese broadswords. In China, the dao is considered one of the four traditional weapons, along with the gun (stick or staff), qiang (spear), and the jian (sword). It is considered "The General of All Weapons".
Name
In Chinese, the word 刀 can be applied to any weapon with a single-edged blade and usually refers to knives. Because of this, the term is sometimes translated as knife or sword-knife. Nonetheless, within Chinese martial arts and in military contexts, the larger "sword" versions of the dao are usually intended.
General characteristics
While dao have varied greatly over the centuries, most single-handed dao of the Ming period and later, and the modern swords that are based (sometimes loosely) on them share a number of characteristics. Dao blades are moderately curved and single-edged, though often with a few inches of the back edge sharpened as well; the moderate curve allows them to be reasonably effective in the thrust. Hilts are sometimes canted, curving in the opposite direction as the blade which improves handling in some forms of cuts and thrusts. Cord is usually wrapped over the wood of the handle. Hilts may also be pierced like those of jian (straight-bladed Chinese sword) for the addition of lanyards, though modern swords for performances will often have tassels or scarves instead. Guards are typically disc-shaped often with a cupped shape to prevent rainwater from getting into the sheath, and to prevent blood from dripping down to the handle, making it more difficult to grip. Sometimes guards are thinner pieces of metal with an s-curve, the lower limb of the curve protecting the user's knuckles; very rarely they may have guards like those of the jian.
So here’s the roundup of the best of Baekhyun, whose magical vocals have been a strength of EXO since their debut ... made the song an all-time favorite of EXO fans, recording over 56 million views.
Siwa’s idea of GayPop quickly spread online, sparking mixed reactions. Some people felt she was ignoring queer pop stars who’ve been around much longer ... ALSO READ. 5 K-pop groups with best vocals according to fans; SNSD, GFRIEND, EXO, and more ... .
5 K-pop groups with best vocals according to fans; SNSD, GFRIEND, EXO, and more ...Today let’s check out the K-pop groups with the best vocals that never fail to impress their loyal fandoms. Check out 5 K-pop groups with astounding vocal skills.
3rd Generation of K-Pop has had some iconic idols come out of it so let’s take a look at some of the best performers like BTS’ Jimin, BLACKPINK’s Lisa and more. BTS’ Jimin, BLACKPINK’s Lisa, >EXO’s Kai and more. 7 best 3rd Gen K-Pop performers.
