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Saturday, 28 December 2024

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CD34

Hematopoietic progenitor cell antigen CD34 also known as CD34 antigen is a protein that in humans is encoded by the CD34 gene.

CD34 is a cluster of differentiation in a cell surface glycoprotein and functions as a cell-cell adhesion factor. It may also mediate the attachment of stem cells to bone marrow extracellular matrix or directly to stromal cells.

Function

The CD34 protein is a member of a family of single-pass transmembrane sialomucin proteins that show expression on early hematopoietic and vascular-associated tissue. However, little is known about its exact function.

CD34 is also an important adhesion molecule and is required for T cells to enter lymph nodes. It is expressed on lymph node endothelia, whereas the L-selectin to which it binds is on the T cell. Conversely, under other circumstances CD34 has been shown to act as molecular "Teflon" and block mast cell, eosinophil and dendritic cell precursor adhesion, and to facilitate opening of vascular lumens. Finally, recent data suggest CD34 may also play a more selective role in chemokine-dependent migration of eosinophils and dendritic cell precursors. Regardless of its mode of action, under all circumstances CD34, and its relatives podocalyxin and endoglycan, facilitates cell migration.

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This page contains text from Wikipedia, the Free Encyclopedia - https://wn.com/CD34

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'); } else { var query = elem.find('.keywords').html(); $.ajax({ context: elem, url: 'https://wn.com/api/upge/cheetah-search-adv/video', cache: true, data: { 'query': query }, dataType: 'jsonp', success: function(text) { if (text.length > 0) { video_id = text[0].id; elem.find('.player').html('

'); } } }); } } var stopAllYouTubeVideos = function() { var iframes = document.querySelectorAll('iframe'); Array.prototype.forEach.call(iframes, function(iframe) { iframe.contentWindow.postMessage(JSON.stringify({ event: 'command', func: 'pauseVideo' }), '*'); }); } jQuery(function() { jQuery(".playVideo").live("click", function() { if(!$(this).hasClass("played")){ stopAllYouTubeVideos(); var elem = $(this); setTimeout(function(){ mouseOverMe(elem); }, 1000); } }); jQuery(".description_box .expandContent").live("click", function() { elem = $(this).parent().parent().parent().find('.descContent'); if(elem.height() > 51) { elem.css('height', '44px'); $(this).html('Show More '); }else{ elem.css('height', 'auto'); $(this).html('Hide '); } }); jQuery('.interview-play-off').click(function() { $(".interview-play-off").hide(); $(".interview-play").show(); $(".videoplayer-control-pause").click(); }); jQuery(".video-desc .show_author_videos").live("click", function() { query = $(this).attr('title'); container = $(this).parent().parent().parent().find('.video-author-thumbs'); $(this).parent().parent().parent().find('.video-author-thumbs').css('height', '220px'); jQuery.ajax({ url: '/api/upge/cheetah-photo-search/videoresults', data: {'query': query}, success: function(text) { if(!text) { text = i18n("No results"); } container.html(jQuery(text)); } }); }); }); // -->

• YOU GOT ME

  by Keith Sweat
• Hood Sex

  by Keith Sweat
• Funky Dope Lovin

  by Keith Sweat
• Genius Girl

  by Keith Sweat
• Test Drive (feat. Joe)

  by Keith Sweat
• You Know I Like

  by Keith Sweat
• Nature's Rising (Interlude)

  by Keith Sweat
• What Goes Around

  by Keith Sweat
• I'm The One You Want

  by Keith Sweat
• Where Did I Go Wrong?

  by Keith Sweat
• Full Time Lover

  by Keith Sweat
• Some More

  by Keith Sweat
• Too Hot

  by Keith Sweat
• Keep It Comin' (Smooth Version)

  by Keith Sweat
• Give Me What I Want

  by Keith Sweat
• Keep It Comin'

  by Keith Sweat
• Chocolate Girl

  by Keith Sweat
• Freak With Me

  by Keith Sweat
• Just Another Day

  by Keith Sweat
• Come Back *

  by Keith Sweat
• Interlude (Live)

  by Keith Sweat
• Show U What Love Is (feat. Ol Skool)

  by Keith Sweat
• Feel So Good

  by Keith Sweat
• In Your Eyes

  by Keith Sweat
• Telephone Love

  by Keith Sweat
• I'm Going For Mine

  by Keith Sweat
• For You (you Got Everything)

  by Keith Sweat
• Ready

  by Keith Sweat
• Do Wrong Tonight

  by Keith Sweat
• Can We Make Love

  by Keith Sweat
• Ten Commandments Of Love

  by Keith Sweat
• Merry Go Round

  by Keith Sweat
• One On Left

  by Keith Sweat
• Just One Of Them Thangs - Duet With Gerald Levert

  by Keith Sweat
• Feels So Good

  by Keith Sweat
• My Body

  by Keith Sweat
• Tropical

  by Keith Sweat
• Me And My Girl

  by Keith Sweat
• Why Me Baby (part 2)

  by Keith Sweat
• It's All About You

  by Keith Sweat
• What's A Man To Do

  by Keith Sweat
• All The Times

  by Keith Sweat
• GIRL OF MY DREAMS

  by Keith Sweat
• Show Me the Way (Interlude)

  by Keith Sweat
• (there You Go) Tellin' Me No Again

  by Keith Sweat
• We Should Be Together

  by Kidd Video
• You Better Run

  by Kidd Video
• Where Did Our Love Go

  by Kidd Video
• Video To Radio

  by Kidd Video
• All On Me

  by Kidd Kidd

YOU GOT ME

by: Keith Sweat

[Lox]
Uh, yeah, uh huh, yeah
Yeah, yeah, yeah, uh huh, yeah, yeah
It's another one
Uh huh, yeah, yeah
It's another one, and another one
You got me where you want me
You could listen to Levert while leaving the country
And then sweat it out when you feel comfy
Or play Gill to the minute that ou say you're hungry
Uh, you got me where you want me
You could listen to Levert while leaving the country
And then sweat it out when you're feeling comfy
Or play gill to the minute that you say you're hungry
Uh, you got me where you want me
You could listen to Levert while leaving the country
And then Sweat it out when your'e feeling comfy
Or play Gill to the minute that you say you're hungry
[LSG]
I know
You need
Love and understanding
Sometimes
Feel like
I can't give you more of my time
You keep on wanting me
To be there girl
But I can't be
Why you keep stressing me
When you know I'm doing my best
I keep on telling you
I do the best that I can do
How can I get through to you
Everything I do is for you
1 - You got me where you want me
Tell me what you need
Take me baby
Tell me what you want
Anywhere you wanna go is for me
You got me where you want me
I can't keep on going through these changes
The more you doubt me
You keep pusing me away girl
You keep on wanting more
I'm doing my best
I'm doing everything for you
Repeat 1
Girl, you got me yearning
Yearning to know what I'll do with love
Can you tell me what I'm doing
But I'm always saying you don't understand
I'll never leave you alone
Repeat 1
Repeat Lox

Latest News for: cd34

Edit

BioLineRx Announces Oral Presentation on Data from Phase 1 Clinical Trial Evaluating Motixafortide for CD34+ ...

Victoria Advocate 05 Nov 2024

- Findings suggest motixafortide alone, and in combination with natalizumab, could support the collection of the large number of stem cells required by gene therapies for sickle cell disease within a single apheresis cycle - ....

Edit

BioLineRx Announces Oral Presentation on Data from Phase 1 Clinical Trial Evaluating Motixafortide for CD34+ Hematopoietic Stem Cell Mobilization for Gene Therapies in Sickle Cell Disease at ASH 2024

PR Newswire 05 Nov 2024

Motixafortide alone, and in combination with natalizumab, resulted in robust CD34+ HSC mobilization to peripheral blood (PB). Motixafortide alone mobilized a median of 198 CD34+ cells/μl (range 77-690) ...

Edit

BioLineRx Announces Oral Presentation on Data from Phase 1 Clinical Trial Evaluating Motixafortide for CD34+ Hematopoietic Stem Cell Mobilization for Gene Therapies in Sickle Cell Disease at ASH 2024 Form 6 K (BioLineRX Ltd)

Public Technologies 05 Nov 2024

Motixafortide for CD34+ Hematopoietic Stem Cell Mobilization for Gene Therapies in Sickle ... Motixafortide alone, and in combination with natalizumab, resulted in robust CD34+ HSC mobilization to peripheral blood (PB).

Edit

Engineering Support

The Engineer 08 Aug 2024

About the job. Job Title. Engineering Support. Location. Bracknell. Salary. £23,400. Job Type. Full-time, Permanent. About BSRIA. ... Exciting work you will be doing. ... In this position you will be working in a friendly environment as part of the Test House ... .

Edit

BioLineRx Announces Clinical Trial Agreement with St. Jude Children’s Research Hospital, Inc. to Evaluate Motixafortide for CD34+ Hematopoietic Stem Cell (HSC) Mobilization For Gene Therapy Applications in Sickle Cell Disease (SCD) (BioLineRX Ltd)

Public Technologies 30 May 2024

). The text version of this document is not available ... Disclaimer. BioLineRX Ltd.

Edit

BioLineRx Announces Clinical Trial Agreement with St. Jude Children's Research Hospital, Inc. to Evaluate Motixafortide for CD34+ Hematopoietic Stem Cell (HSC) Mobilization For Gene Therapy Applications in Sickle Cell Disease (SCD)

PR Newswire 30 May 2024

to evaluate motixafortide for the mobilization of CD34+ hematopoietic stem cells (HSCs) used in the development of gene therapies for patients with sickle cell disease (SCD).&nbsp; Investigators in the trial from St.

Edit

BioLineRx Announces Poster Presentation on Economic Model Data for APHEXDA� (motixafortide) as part of CD34+ ...

Victoria Advocate 06 May 2024

- Presentation Today, Monday, May 6, 2024 in Atlanta, Georgia - ....

Edit

BioLineRx Announces Poster Presentation on Economic Model Data for APHEXDA® (motixafortide) as part of CD34+ Hematopoietic Stem Cell Mobilization in Patients with Multiple Myeloma at ISPOR 2024

PR Newswire 06 May 2024

The new economic model data to be presented at ISPOR 2024 builds on the evaluation of APHEXDA for CD34+ HSC mobilization in patients with multiple myeloma in apheresis center operations.

Edit

BioLineRx Announces Poster Presentation on Economic Model Data for APHEXDA® (motixafortide) as part of CD34+ Hematopoietic Stem Cell Mobilization in Patients with Multiple Myeloma at ISPOR 2024 (BioLineRX Ltd)

Public Technologies 06 May 2024

BioLineRx Announces Poster Presentation on Economic Model Data for APHEXDA® (motixafortide) as part of CD34+ Hematopoietic Stem Cell Mobilization in Patients with Multiple Myeloma at ISPOR 2024.

Edit

CellProthera to share results from its Phase I/IIb study investigating the safety and efficacy of ProtheraCytes (CD34+ expanded stem cells) in acute myocardial infarction

Pharmiweb 23 Apr 2024

CellProthera has developed a unique GMP-compliant cell expansion process as well as a proprietary automation technology for in vitro production of a large quantity of purified CD34+ stem cells.

Edit

BioLineRx Announces Acceptance of Two Poster Presentations on APHEXDA® (motixafortide) for CD34+ Hematopoietic Stem Cell ...

Victoria Advocate 16 Feb 2024

Prolonged CXCR4 Receptor Occupancy By Motixafortide Following a Single Subcutaneous Injection Is Associated with Extended Mobilization of CD34+ Cells in Peripheral Blood for > 24 Hours.

Edit

Beauty-Stem Biomedical Teams Up With S.Y. Dao Cancer Prevention Foundation for Charitable Book Lecture on CD34 Stem Cells and Immunology

Pharmiweb 11 Jan 2024

This dynamic partnership will unveil a charitable book lecture on CD34 stem cells and immunology, co-authored by Dr ... delved into cutting-edge topics related to CD34 stem cells and cancer prevention.

Edit

Biolinerx Announces First Patient Dosed In Phase 1 Clinical Trial Evaluating Motixafortide For CD34+ Hematopoietic ...

MENA FN 21 Dec 2023

(MENAFN - PR Newswire) - Proof-of-conceptstudy is initial step toward goal of identifying more efficient CD34+ HSC mobilization regimen for patients with sickle cell disease choosing gene therapy ... .

Edit

CellProthera expanding into ischemic stroke following publication of positive preclinical results with its CD34+ stem cell platform

Pharmiweb 30 Nov 2023

CellProthera has developed a unique GMP-compliant cell expansion process as well as a proprietary automation technology for&nbsp;in vitro production of a large quantity of purified, CD34+ stem cells.

Edit

BioLineRx Announces First Patient Dosed in Phase 1 Clinical Trial Evaluating Motixafortide for CD34+ Hematopoietic Stem Cell Mobilization for Gene Therapies in Sickle Cell Disease

PR Newswire 22 Mar 2023

- Proof-of-concept&nbsp;study is initial step toward goal of identifying more efficient CD34+ HSC mobilization regimen for patients with sickle cell disease choosing gene therapy -.

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