The motif is characterized by two α-helices connected by a loop. In general, transcription factors including this domain are dimeric, each with one helix containing basicamino acid residues that facilitate DNA binding. In general, one helix is smaller, and, due to the flexibility of the loop, allows dimerization by folding and packing against another helix. The larger helix typically contains the DNA-binding regions. bHLH proteins typically bind to a consensus sequence called an E-box, CANNTG. The canonical E-box is CACGTG (palindromic), however some bHLH transcription factors, notably those of the bHLH-PAS family, bind to related non-palindromic sequences, which are similar to the E-box.
Examples
Examples of transcription factors containing a bHLH include:
This video describes several DNA binding motifs present in wide variety of Transcription factors and also describes how they interact with DNA with proper examples
published: 15 Jul 2018
| HELIX LOOP HELIX | & | HELIX TURN HELIX | Introduction, basic concept and function
WARNING: KEEP THE VOLUME LOW....
here is the new video on helix loop helix and helix turn helix with introduction and binding site on DNA and also the function of those domain..
you have to make efforts of reading those and i make sure that your concept will be clear
published: 26 Oct 2017
Lecture 4 Helix turn Helix motifs
published: 20 Apr 2020
TRANSCRIPTION FACTORS: HELIX-LOOP-HELIX 1
TRANSCRIPTION FACTORS: HELIX-LOOP-HELIX 1
published: 03 Nov 2012
DNA binding motif_2 | Helix-loop-helix
In this video we are going to cover Helix-loop-helix motif.
In our previous video we discussed Helix-turn-helix motif.
Link: https://youtu.be/J8GaoUlX7Go
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published: 12 Jul 2020
Helix Loop Helix Protein | Motifs | Dimer | Structure | Functions | Tamil | Biology | ThiNK VISION
This video is all about
Helix Loop Helix Protein Motifs
Their structure and function
#microbiology #biotechnology #biochemistry #lifescience #biology #Genetics #molecularbiology #immunology #pharmocology #mycology #virology #cellbiology #medicalmicrobiology #bioinformatics #genomics #foodmicrobiology #industrialmicrobiology #rDNAtechnology #proteomics #neet #entranceexam #csirnet #tamil #science #thinkbiology #thinkvision
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published: 08 Nov 2020
Medical vocabulary: What does Basic Helix-Loop-Helix Transcription Factors mean
What does Basic Helix-Loop-Helix Transcription Factors mean in English?
DNA binding motif
(1) Helix turn helix (HTH)
(2) Helix loop helix (HLH)
(3) Zinc finger
(4) Leucine zipper
Hey this is Dr. Malinki. If you are a medical aspirant or pursuing graduation or post-graduation in Life Science, stay with me. I will upload regular video regarding them. I have also started to upload regular videos for UPSC and IFSE optional Zoology. If you do not want to spend money in coaching institutes, stay here to get free lectures. I will cover full syllabus and help to clear your concept. Do not forget to subscribe my channel if you don’t want to miss a single video for your exam. Your subscription will mean a lot to me. If you like my lecture please do like comment and share my videos. This will motivate me to make my next video for you. Thank you.
Learn cloning basics (IN...
published: 06 Dec 2021
Mod-02 Lec-05 Transcription factors : DNA binding domains
Eukaryotic Gene Expression:Basics & Benefits by Prof.P N RANGARAJAN,Department of Biochemistry,IISC Bangalore. For more details on NPTEL visit http://nptel.iitm.ac.in
This video describes several DNA binding motifs present in wide variety of Transcription factors and also describes how they interact with DNA with proper examp...
This video describes several DNA binding motifs present in wide variety of Transcription factors and also describes how they interact with DNA with proper examples
This video describes several DNA binding motifs present in wide variety of Transcription factors and also describes how they interact with DNA with proper examples
WARNING: KEEP THE VOLUME LOW....
here is the new video on helix loop helix and helix turn helix with introduction and binding site on DNA and also the functio...
WARNING: KEEP THE VOLUME LOW....
here is the new video on helix loop helix and helix turn helix with introduction and binding site on DNA and also the function of those domain..
you have to make efforts of reading those and i make sure that your concept will be clear
WARNING: KEEP THE VOLUME LOW....
here is the new video on helix loop helix and helix turn helix with introduction and binding site on DNA and also the function of those domain..
you have to make efforts of reading those and i make sure that your concept will be clear
In this video we are going to cover Helix-loop-helix motif.
In our previous video we discussed Helix-turn-helix motif.
Link: https://youtu.be/J8GaoUlX7Go
You ...
In this video we are going to cover Helix-loop-helix motif.
In our previous video we discussed Helix-turn-helix motif.
Link: https://youtu.be/J8GaoUlX7Go
You can reach us in
Instagram : instagram.com/sb_make.it.simple
Facebook page:
https://m.facebook.com/Mathematics-and-Biology-102460498201631/?ref=bookmarks
In this video we are going to cover Helix-loop-helix motif.
In our previous video we discussed Helix-turn-helix motif.
Link: https://youtu.be/J8GaoUlX7Go
You can reach us in
Instagram : instagram.com/sb_make.it.simple
Facebook page:
https://m.facebook.com/Mathematics-and-Biology-102460498201631/?ref=bookmarks
This video is all about
Helix Loop Helix Protein Motifs
Their structure and function
#microbiology #biotechnology #biochemistry #lifescience #biology #Genetics...
This video is all about
Helix Loop Helix Protein Motifs
Their structure and function
#microbiology #biotechnology #biochemistry #lifescience #biology #Genetics #molecularbiology #immunology #pharmocology #mycology #virology #cellbiology #medicalmicrobiology #bioinformatics #genomics #foodmicrobiology #industrialmicrobiology #rDNAtechnology #proteomics #neet #entranceexam #csirnet #tamil #science #thinkbiology #thinkvision
Presented by : T. N. Kumaresan (TNK)
Keep loving supporting and thinking ThiNK BIOLOGY ThiNK VISION...! ❤️
Keep in Touch with us...
Instagram :https://www.instagram.com/thinkbiology_think_vision/
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Email: [email protected]
This video is all about
Helix Loop Helix Protein Motifs
Their structure and function
#microbiology #biotechnology #biochemistry #lifescience #biology #Genetics #molecularbiology #immunology #pharmocology #mycology #virology #cellbiology #medicalmicrobiology #bioinformatics #genomics #foodmicrobiology #industrialmicrobiology #rDNAtechnology #proteomics #neet #entranceexam #csirnet #tamil #science #thinkbiology #thinkvision
Presented by : T. N. Kumaresan (TNK)
Keep loving supporting and thinking ThiNK BIOLOGY ThiNK VISION...! ❤️
Keep in Touch with us...
Instagram :https://www.instagram.com/thinkbiology_think_vision/
Twitter: https://twitter.com/BiologyThink
Facebook: https://www.facebook.com/ThiNKVison/
Email: [email protected]
DNA binding motif
(1) Helix turn helix (HTH)
(2) Helix loop helix (HLH)
(3) Zinc finger
(4) Leucine zipper
Hey this is Dr. Malinki. If you are a medical aspira...
DNA binding motif
(1) Helix turn helix (HTH)
(2) Helix loop helix (HLH)
(3) Zinc finger
(4) Leucine zipper
Hey this is Dr. Malinki. If you are a medical aspirant or pursuing graduation or post-graduation in Life Science, stay with me. I will upload regular video regarding them. I have also started to upload regular videos for UPSC and IFSE optional Zoology. If you do not want to spend money in coaching institutes, stay here to get free lectures. I will cover full syllabus and help to clear your concept. Do not forget to subscribe my channel if you don’t want to miss a single video for your exam. Your subscription will mean a lot to me. If you like my lecture please do like comment and share my videos. This will motivate me to make my next video for you. Thank you.
Learn cloning basics (INR 999/-)
https://www.youtube.com/watch?v=-MqND10Jf8w&t=13s
Day 1: What is cloning? What is a vector? Difference between cloning vector and expression vector
Structure of a vector. How to read vector map?
What is Multiple Cloning Site (MCS)?
Steps of cloning
Day 2: How to set up a PCR reaction?
Agarose Gel Electrophoresis
PCR product extraction and purification from gel
Restriction digestion
Ligation
Transformation
Learn primer designing (INR 499/-)
https://www.youtube.com/watch?v=mg8abyMWuIY
Customize your primers for super successful cloning
What are we offering?
Extract DNA sequence from NCBI database
Identify CDS (ORF) from whole gene sequence
Make best customized primers for PCR, q-PCR, mutant PCR, deletion mutation, point mutation
Special offer: Get package 1 and 2 @ INR 1299/-.
Bonus: Discussion of your unsuccessful PCR in lab for free
All packages consist of full customized protocols provided in PDF
WhatsApp or call me at 9019765145 or mail me at [email protected]
DNA binding motif
(1) Helix turn helix (HTH)
(2) Helix loop helix (HLH)
(3) Zinc finger
(4) Leucine zipper
Hey this is Dr. Malinki. If you are a medical aspirant or pursuing graduation or post-graduation in Life Science, stay with me. I will upload regular video regarding them. I have also started to upload regular videos for UPSC and IFSE optional Zoology. If you do not want to spend money in coaching institutes, stay here to get free lectures. I will cover full syllabus and help to clear your concept. Do not forget to subscribe my channel if you don’t want to miss a single video for your exam. Your subscription will mean a lot to me. If you like my lecture please do like comment and share my videos. This will motivate me to make my next video for you. Thank you.
Learn cloning basics (INR 999/-)
https://www.youtube.com/watch?v=-MqND10Jf8w&t=13s
Day 1: What is cloning? What is a vector? Difference between cloning vector and expression vector
Structure of a vector. How to read vector map?
What is Multiple Cloning Site (MCS)?
Steps of cloning
Day 2: How to set up a PCR reaction?
Agarose Gel Electrophoresis
PCR product extraction and purification from gel
Restriction digestion
Ligation
Transformation
Learn primer designing (INR 499/-)
https://www.youtube.com/watch?v=mg8abyMWuIY
Customize your primers for super successful cloning
What are we offering?
Extract DNA sequence from NCBI database
Identify CDS (ORF) from whole gene sequence
Make best customized primers for PCR, q-PCR, mutant PCR, deletion mutation, point mutation
Special offer: Get package 1 and 2 @ INR 1299/-.
Bonus: Discussion of your unsuccessful PCR in lab for free
All packages consist of full customized protocols provided in PDF
WhatsApp or call me at 9019765145 or mail me at [email protected]
Eukaryotic Gene Expression:Basics & Benefits by Prof.P N RANGARAJAN,Department of Biochemistry,IISC Bangalore. For more details on NPTEL visit http://nptel.iitm...
Eukaryotic Gene Expression:Basics & Benefits by Prof.P N RANGARAJAN,Department of Biochemistry,IISC Bangalore. For more details on NPTEL visit http://nptel.iitm.ac.in
Eukaryotic Gene Expression:Basics & Benefits by Prof.P N RANGARAJAN,Department of Biochemistry,IISC Bangalore. For more details on NPTEL visit http://nptel.iitm.ac.in
This video describes several DNA binding motifs present in wide variety of Transcription factors and also describes how they interact with DNA with proper examples
WARNING: KEEP THE VOLUME LOW....
here is the new video on helix loop helix and helix turn helix with introduction and binding site on DNA and also the function of those domain..
you have to make efforts of reading those and i make sure that your concept will be clear
In this video we are going to cover Helix-loop-helix motif.
In our previous video we discussed Helix-turn-helix motif.
Link: https://youtu.be/J8GaoUlX7Go
You can reach us in
Instagram : instagram.com/sb_make.it.simple
Facebook page:
https://m.facebook.com/Mathematics-and-Biology-102460498201631/?ref=bookmarks
This video is all about
Helix Loop Helix Protein Motifs
Their structure and function
#microbiology #biotechnology #biochemistry #lifescience #biology #Genetics #molecularbiology #immunology #pharmocology #mycology #virology #cellbiology #medicalmicrobiology #bioinformatics #genomics #foodmicrobiology #industrialmicrobiology #rDNAtechnology #proteomics #neet #entranceexam #csirnet #tamil #science #thinkbiology #thinkvision
Presented by : T. N. Kumaresan (TNK)
Keep loving supporting and thinking ThiNK BIOLOGY ThiNK VISION...! ❤️
Keep in Touch with us...
Instagram :https://www.instagram.com/thinkbiology_think_vision/
Twitter: https://twitter.com/BiologyThink
Facebook: https://www.facebook.com/ThiNKVison/
Email: [email protected]
DNA binding motif
(1) Helix turn helix (HTH)
(2) Helix loop helix (HLH)
(3) Zinc finger
(4) Leucine zipper
Hey this is Dr. Malinki. If you are a medical aspirant or pursuing graduation or post-graduation in Life Science, stay with me. I will upload regular video regarding them. I have also started to upload regular videos for UPSC and IFSE optional Zoology. If you do not want to spend money in coaching institutes, stay here to get free lectures. I will cover full syllabus and help to clear your concept. Do not forget to subscribe my channel if you don’t want to miss a single video for your exam. Your subscription will mean a lot to me. If you like my lecture please do like comment and share my videos. This will motivate me to make my next video for you. Thank you.
Learn cloning basics (INR 999/-)
https://www.youtube.com/watch?v=-MqND10Jf8w&t=13s
Day 1: What is cloning? What is a vector? Difference between cloning vector and expression vector
Structure of a vector. How to read vector map?
What is Multiple Cloning Site (MCS)?
Steps of cloning
Day 2: How to set up a PCR reaction?
Agarose Gel Electrophoresis
PCR product extraction and purification from gel
Restriction digestion
Ligation
Transformation
Learn primer designing (INR 499/-)
https://www.youtube.com/watch?v=mg8abyMWuIY
Customize your primers for super successful cloning
What are we offering?
Extract DNA sequence from NCBI database
Identify CDS (ORF) from whole gene sequence
Make best customized primers for PCR, q-PCR, mutant PCR, deletion mutation, point mutation
Special offer: Get package 1 and 2 @ INR 1299/-.
Bonus: Discussion of your unsuccessful PCR in lab for free
All packages consist of full customized protocols provided in PDF
WhatsApp or call me at 9019765145 or mail me at [email protected]
Eukaryotic Gene Expression:Basics & Benefits by Prof.P N RANGARAJAN,Department of Biochemistry,IISC Bangalore. For more details on NPTEL visit http://nptel.iitm.ac.in
The motif is characterized by two α-helices connected by a loop. In general, transcription factors including this domain are dimeric, each with one helix containing basicamino acid residues that facilitate DNA binding. In general, one helix is smaller, and, due to the flexibility of the loop, allows dimerization by folding and packing against another helix. The larger helix typically contains the DNA-binding regions. bHLH proteins typically bind to a consensus sequence called an E-box, CANNTG. The canonical E-box is CACGTG (palindromic), however some bHLH transcription factors, notably those of the bHLH-PAS family, bind to related non-palindromic sequences, which are similar to the E-box.
Examples
Examples of transcription factors containing a bHLH include:
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Recent research has uncovered the genetic mechanisms behind sea lavender's (Limonium bicolor) salt tolerance by studying basic helix–loop–helix (bHLH) transcription factors ...Basic ...
This study unveils the intricate role of TT8, a basic helix-loop-helix (bHLH) transcription factor, in anthocyanin biosynthesis and fruit quality in blood orange, focusing on the effects of alternative splicing.
While the role of basic helix-loop-helix (bHLH) transcription factors (TFs) in regulating secondary metabolites like phenolic compounds is well-documented, their specific involvement in IB, ...
Donovan et al, Basic helix-loop-helix pioneer factors interact with the histone octamer to invade nucleosomes and generate nucleosome-depleted regions, Molecular Cell (2023).
The basic helix-loop-helix (bHLH) subgroup IIIe transcription factors MYC2, MYC3, and MYC4 are the most extensively characterized JAZ-binding factors and together stimulate jasmonate-signaled primary root growth inhibition ... More information ... DOI ... ....