-
Pharmacology - ANTIEPILEPTIC DRUGS (MADE EASY)
👉📖 READY TO ACE YOUR EXAM? 📚 GET STUDY NOTES ON PATREON!
https://www.patreon.com/speedpharmacology
Antiepileptic drugs, also referred to as anticonvulsants, are a diverse group of medications used in the treatment of epileptic seizures. Antiepileptics work in a number of different ways to inhibit or slow down neuronal firing to prevent seizures from occurring. This pharmacology lecture covers topics such as pathophysiology and classification of seizures, action potential, excitatory and inhibitory neurotransmission (role of glutamate and GABA), voltage-gated sodium and calcium channels, AMPA and NMDA receptors, mechanism of action and side effects of antiepileptic drugs. Drugs mentioned include; Carbamazepine, Oxcarbazepine, Lamotrigine, Phenytoin, Topiramate, Valproic acid, Zonisamide, G...
published: 15 Nov 2018
-
Epilepsy & Its Types | Anticonvulsant Antiepileptic || L- 12 Unit-4 Medicinal Chemistry -I
For downloading pdf notes of this chapter in very easy language visit our website
Our Official Website
https://kclpharmacy.com/
------------------------------------------------------------------------------------------------------------------ About this video -
Topic - Epilepsy & Its Types | Anticonvulsant Antiepileptic || L- 12 Unit-4 Medicinal Chemistry -I
Subject – Medicinal Chemistry
Anti-Psychosis - Tricky Classification हसते हसते चुटकियो में याद - https://youtu.be/z6CJa5UTKvU
B.Pharm – 4th sem
D.Pharm- 2nd year
FOR B.PHARM, D.PHARM & M.PHARM STUDENTS
Hello Students
I am Anurag Jaiswal. I am working as Assistant Professor in a Pharmacy College and trainer in Vibgyor Laboratories.
By ANURAG JAISWAL
M.Pharm (GPAT Qualified)
For downloading pdf notes of this chapter on very...
published: 29 Apr 2020
-
Drug of choice For Various types of Seizures / Anticonvulsant drugs - Pharmacology Fmge and Neet pg
📌 𝐅𝐨𝐥𝐥𝐨𝐰 𝐨𝐧 𝐈𝐧𝐬𝐭𝐚𝐠𝐫𝐚𝐦:- https://www.instagram.com/drgbhanuprakash
📌𝗝𝗼𝗶𝗻 𝗢𝘂𝗿 𝗧𝗲𝗹𝗲𝗴𝗿𝗮𝗺 𝗖𝗵𝗮𝗻𝗻𝗲𝗹 𝗛𝗲𝗿𝗲:- https://t.me/bhanuprakashdr
📌𝗦𝘂𝗯𝘀𝗰𝗿𝗶𝗯𝗲 𝗧𝗼 𝗠𝘆 𝗠𝗮𝗶𝗹𝗶𝗻𝗴 𝗟𝗶𝘀𝘁:- https://linktr.ee/DrGBhanuprakash
Drug of choice For Various tyoes of Seizures - Pharmacology Fmge and Neet pg
Anticonvulsant drugs are classified as either classic or newer anticonvulsants. Newer anticonvulsants are usually better tolerated and have a broader therapeutic range than classic anticonvulsant drugs. The choice of drug is guided by the type of seizure. First-line treatment for focal seizures includes e.g., lamotrigine or levetiracetam, while valproate is used for generalized seizures. All anticonvulsants have dose-dependent side effects on the central nervous system such as somnolence and nausea, but some agents have ...
published: 23 Dec 2019
-
Antiepileptic Anticonvulsant - Trick to learn Classification
Number =
published: 28 Apr 2020
-
Mode of Action & SAR of Antiepileptic | Anticonvulsant || L- 13 Unit-4 Medicinal Chemistry -I
About this video -
Topic - Mode of Action & SAR of Antiepileptic | Anticonvulsant || L- 13 Unit-4 Medicinal Chemistry -I
Subject – Medicinal Chemistry
Anti-Psychosis - Tricky Classification हसते हसते चुटकियो में याद - https://youtu.be/z6CJa5UTKvU
B.Pharm – 4th sem
D.Pharm- 2nd year
FOR B.PHARM, D.PHARM & M.PHARM STUDENTS
Hello Students
I am Anurag Jaiswal. I am working as Assistant Professor in a Pharmacy College and trainer in Vibgyor Laboratories.
By ANURAG JAISWAL
M.Pharm (GPAT Qualified)
For downloading pdf notes of this chapter on very easy language visit our website
Our Official Website
www.kclpharmacy.com
Facebook Page
https://www.facebook.com/anurag.jaiswal.1291
Youtube Channel
https://youtube.com/c/KclTutorial
Email- [email protected]
Ask anything about th...
published: 29 Apr 2020
-
Anticonvulsants (antiepileptic drugs)
This is a brief summary of anticonvulsants, or medicines used to treat epilepsy.
I created this presentation with Google Slides.
Image were created or taken from Wikimedia Commons
I created this video with the YouTube Video Editor.
ADDITIONAL TAGS:
Anticonvulsants
Drug
Mechanism of action
Modern approach
Other indications
Side effects (unique/notable listed first)
Interaction
Metab
Carbamazepine
Na+ channel blocker: binds inactive Na channel, extend inactivation
simple partial, complex partial, secondary generalized (narrow)
bipolar disorder, trigeminal neuralgia
Hyponatremia... bone marrow suppression; hepatotox; sedation; dizziness; n/v; double vision; ataxia; fetal malform; bone demineraliz; Stevens-Johnson syndrome
p450 induction
hepatic
Phenytoin
Na+ channel blocker: complex actio...
published: 22 May 2016
-
Anti epileptic Drugs / Anticonvulsants : Carbamazepine & Oxcarbamazepine : CNS Pharmacology
►𝐉𝐨𝐢𝐧 𝐓𝐡𝐢𝐬 𝐂𝐡𝐚𝐧𝐧𝐞𝐥 𝐓𝐨 𝐆𝐞𝐭 𝐀𝐜𝐜𝐞𝐬𝐬 𝐓𝐨 𝐏𝐞𝐫𝐤𝐬 :- https://bit.ly/2RQHvTN
💻 𝗔𝗰𝗰𝗲𝘀𝘀 𝟭𝟬𝟬+ 𝗵𝗼𝘂𝗿𝘀 𝗼𝗳 𝗣𝗵𝗮𝗿𝗺𝗮𝗰𝗼𝗹𝗼𝗴𝘆 𝘃𝗶𝗱𝗲𝗼 𝗹𝗲𝗰𝘁𝘂𝗿𝗲𝘀 𝘁𝗵𝗿𝗼𝘂𝗴𝗵 𝗺𝗲𝗱𝘃𝗶𝘇𝘇 𝗮𝗽𝗽
👉 𝗔𝗽𝗽 𝗟𝗶𝗻𝗸 :- https://bit.ly/3kbDWTO
👉 𝗖𝗼𝘂𝗿𝘀𝗲 𝗟𝗶𝗻𝗸 :- https://bit.ly/3hCYfbg
📌𝐅𝐨𝐥𝐥𝐨𝐰 𝐨𝐧 𝐈𝐧𝐬𝐭𝐚𝐠𝐫𝐚𝐦 :-
https://www.instagram.com/drgbhanuprakash
Anticonvulsant drugs are classified as either classic or newer anticonvulsants. Newer anticonvulsants are usually better tolerated and have a broader therapeutic range than classic anticonvulsant drugs. The choice of drug is guided by the type of seizure. First-line treatment for focal seizures includes e.g., lamotrigine or levetiracetam, while valproate is used for generalized seizures. All anticonvulsants have dose-dependent side effects on the central nervous system such as somnolence and nausea, but some...
published: 06 Jan 2020
-
Antiepileptic Drugs (Part 01)= General Introduction, Types and Classifications of Epilepsy (HINDI)
Download "Solution Pharmacy" Mobile App to Get All Uploaded Notes, Model Question Papers, Answer Papers, Online Test and other GPAT Materials - https://play.google.com/store/apps/details?id=co.bolton.nqilv
Free model question paper for pharmacology 01 (All units) –
https://drive.google.com/drive/folders/1d61HhxtPwkK3TqY2ZD45z_shGayyG3xO?usp=sharing
Free Pharmacology- 1 notes (made by students) –
https://drive.google.com/open?id=1PRaNYy7_a60FCIpDzKTIK4gxOLhBclFQ
Epilepsy is a central nervous system (neurological) disorder in which brain activity becomes abnormal, causing seizures or periods of unusual behaviour, sensations, and sometimes loss of awareness.
Seizure symptoms can vary widely. Some people with epilepsy simply stare blankly for a few seconds during a seizure, while others ...
published: 12 May 2019
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Anticonvulsant drugs structure and IUPAC names Antiepileptic drugs
Adrenergic drugs: https://www.youtube.com/watch?v=wUn1BjXY63o
Antiadrenergic drugs: https://www.youtube.com/watch?v=6S5MUc5F37A
Metabolism of catecholamines: https://www.youtube.com/watch?v=R6ddwyVmZq4
Cholinergic drugs: https://www.youtube.com/watch?v=KM11NReVn8k
Anticholinergic drugs: https://www.youtube.com/watch?v=cUOBOU9lL3M
Sedatives and Hypnotics: https://www.youtube.com/watch?v=b7iR8pgOEYs
Antipsychotic drugs: https://www.youtube.com/watch?v=5t77q-0Wz2M
published: 31 Mar 2020
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Pharmacology - Seizures (Epilepsy) drugs for nursing RN PN NCLEX
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SimpleNursing memberships have 1,200+ animated videos, 900+ colorful study guides, 3,000+ practice questions, and more! See why SimpleNursing is trusted by over 1,000,000 nursing students.
Today’s video is all about epilepsy anticonvulsant drugs for Nursing Students and NCLEX Review.
Anticonvulsant drugs are used to treat seizures (from epilepsy), which are sudden abnormal electrical discharges from nerve cells in the brain. These drugs help prevent brain seizures by blocking the spread of neuronal activity that causes them.
The most common anticonvulsant drugs include Levetiracetam and Phenytoin – and both have dif...
published: 22 Feb 2021
8:33
Pharmacology - ANTIEPILEPTIC DRUGS (MADE EASY)
👉📖 READY TO ACE YOUR EXAM? 📚 GET STUDY NOTES ON PATREON!
https://www.patreon.com/speedpharmacology
Antiepileptic drugs, also referred to as anticonvulsants, ar...
👉📖 READY TO ACE YOUR EXAM? 📚 GET STUDY NOTES ON PATREON!
https://www.patreon.com/speedpharmacology
Antiepileptic drugs, also referred to as anticonvulsants, are a diverse group of medications used in the treatment of epileptic seizures. Antiepileptics work in a number of different ways to inhibit or slow down neuronal firing to prevent seizures from occurring. This pharmacology lecture covers topics such as pathophysiology and classification of seizures, action potential, excitatory and inhibitory neurotransmission (role of glutamate and GABA), voltage-gated sodium and calcium channels, AMPA and NMDA receptors, mechanism of action and side effects of antiepileptic drugs. Drugs mentioned include; Carbamazepine, Oxcarbazepine, Lamotrigine, Phenytoin, Topiramate, Valproic acid, Zonisamide, Gabapentin, Pregabalin, Levetiracetam, Felbamate, Tiagabine, and Vigabatrin.
Thanks for watching and don't forget to SUBSCRIBE, hit the LIKE button👍 and click the BELL button🔔 for future notifications!!!
0:00 Seizure classification
1:07 Excitatory synapse
2:44 Inhibitory neuron
3:51 Antiepileptics - mechanism of action
7:26 Side effects
https://wn.com/Pharmacology_Antiepileptic_Drugs_(Made_Easy)
👉📖 READY TO ACE YOUR EXAM? 📚 GET STUDY NOTES ON PATREON!
https://www.patreon.com/speedpharmacology
Antiepileptic drugs, also referred to as anticonvulsants, are a diverse group of medications used in the treatment of epileptic seizures. Antiepileptics work in a number of different ways to inhibit or slow down neuronal firing to prevent seizures from occurring. This pharmacology lecture covers topics such as pathophysiology and classification of seizures, action potential, excitatory and inhibitory neurotransmission (role of glutamate and GABA), voltage-gated sodium and calcium channels, AMPA and NMDA receptors, mechanism of action and side effects of antiepileptic drugs. Drugs mentioned include; Carbamazepine, Oxcarbazepine, Lamotrigine, Phenytoin, Topiramate, Valproic acid, Zonisamide, Gabapentin, Pregabalin, Levetiracetam, Felbamate, Tiagabine, and Vigabatrin.
Thanks for watching and don't forget to SUBSCRIBE, hit the LIKE button👍 and click the BELL button🔔 for future notifications!!!
0:00 Seizure classification
1:07 Excitatory synapse
2:44 Inhibitory neuron
3:51 Antiepileptics - mechanism of action
7:26 Side effects
- published: 15 Nov 2018
- views: 938243
20:01
Epilepsy & Its Types | Anticonvulsant Antiepileptic || L- 12 Unit-4 Medicinal Chemistry -I
For downloading pdf notes of this chapter in very easy language visit our website
Our Official Website
https://kclpharmacy.com/
------------------------------...
For downloading pdf notes of this chapter in very easy language visit our website
Our Official Website
https://kclpharmacy.com/
------------------------------------------------------------------------------------------------------------------ About this video -
Topic - Epilepsy & Its Types | Anticonvulsant Antiepileptic || L- 12 Unit-4 Medicinal Chemistry -I
Subject – Medicinal Chemistry
Anti-Psychosis - Tricky Classification हसते हसते चुटकियो में याद - https://youtu.be/z6CJa5UTKvU
B.Pharm – 4th sem
D.Pharm- 2nd year
FOR B.PHARM, D.PHARM & M.PHARM STUDENTS
Hello Students
I am Anurag Jaiswal. I am working as Assistant Professor in a Pharmacy College and trainer in Vibgyor Laboratories.
By ANURAG JAISWAL
M.Pharm (GPAT Qualified)
For downloading pdf notes of this chapter on very easy language visit our website
Our Official Website
www.kclpharmacy.com
Facebook Page
https://www.facebook.com/anurag.jaiswal.1291
Youtube Channel
https://youtube.com/c/KclTutorial
Email-
[email protected]
Ask anything about this topic on comment section.About this video - Number =
https://wn.com/Epilepsy_Its_Types_|_Anticonvulsant_Antiepileptic_||_L_12_Unit_4_Medicinal_Chemistry_I
For downloading pdf notes of this chapter in very easy language visit our website
Our Official Website
https://kclpharmacy.com/
------------------------------------------------------------------------------------------------------------------ About this video -
Topic - Epilepsy & Its Types | Anticonvulsant Antiepileptic || L- 12 Unit-4 Medicinal Chemistry -I
Subject – Medicinal Chemistry
Anti-Psychosis - Tricky Classification हसते हसते चुटकियो में याद - https://youtu.be/z6CJa5UTKvU
B.Pharm – 4th sem
D.Pharm- 2nd year
FOR B.PHARM, D.PHARM & M.PHARM STUDENTS
Hello Students
I am Anurag Jaiswal. I am working as Assistant Professor in a Pharmacy College and trainer in Vibgyor Laboratories.
By ANURAG JAISWAL
M.Pharm (GPAT Qualified)
For downloading pdf notes of this chapter on very easy language visit our website
Our Official Website
www.kclpharmacy.com
Facebook Page
https://www.facebook.com/anurag.jaiswal.1291
Youtube Channel
https://youtube.com/c/KclTutorial
Email-
[email protected]
Ask anything about this topic on comment section.About this video - Number =
- published: 29 Apr 2020
- views: 72426
2:04
Drug of choice For Various types of Seizures / Anticonvulsant drugs - Pharmacology Fmge and Neet pg
📌 𝐅𝐨𝐥𝐥𝐨𝐰 𝐨𝐧 𝐈𝐧𝐬𝐭𝐚𝐠𝐫𝐚𝐦:- https://www.instagram.com/drgbhanuprakash
📌𝗝𝗼𝗶𝗻 𝗢𝘂𝗿 𝗧𝗲𝗹𝗲𝗴𝗿𝗮𝗺 𝗖𝗵𝗮𝗻𝗻𝗲𝗹 𝗛𝗲𝗿𝗲:- https://t.me/bhanuprakashdr
📌𝗦𝘂𝗯𝘀𝗰𝗿𝗶𝗯𝗲 𝗧𝗼 𝗠𝘆 𝗠𝗮𝗶𝗹𝗶𝗻𝗴 𝗟𝗶𝘀𝘁:- ...
📌 𝐅𝐨𝐥𝐥𝐨𝐰 𝐨𝐧 𝐈𝐧𝐬𝐭𝐚𝐠𝐫𝐚𝐦:- https://www.instagram.com/drgbhanuprakash
📌𝗝𝗼𝗶𝗻 𝗢𝘂𝗿 𝗧𝗲𝗹𝗲𝗴𝗿𝗮𝗺 𝗖𝗵𝗮𝗻𝗻𝗲𝗹 𝗛𝗲𝗿𝗲:- https://t.me/bhanuprakashdr
📌𝗦𝘂𝗯𝘀𝗰𝗿𝗶𝗯𝗲 𝗧𝗼 𝗠𝘆 𝗠𝗮𝗶𝗹𝗶𝗻𝗴 𝗟𝗶𝘀𝘁:- https://linktr.ee/DrGBhanuprakash
Drug of choice For Various tyoes of Seizures - Pharmacology Fmge and Neet pg
Anticonvulsant drugs are classified as either classic or newer anticonvulsants. Newer anticonvulsants are usually better tolerated and have a broader therapeutic range than classic anticonvulsant drugs. The choice of drug is guided by the type of seizure. First-line treatment for focal seizures includes e.g., lamotrigine or levetiracetam, while valproate is used for generalized seizures. All anticonvulsants have dose-dependent side effects on the central nervous system such as somnolence and nausea, but some agents have more specific side effects (e.g., gingival hyperplasia caused by phenytoin).
Besides their importance in anti-epileptic therapy, anticonvulsants are also used for pain management (e.g., carbamazepine or gabapentin as coanalgesics) or as mood stabilizers in bipolar disorders (valproate).
#Anticonvulsants #drugofchoiceforseizures #anticonvulsant #anticonvulsantdrugs #antiepileptictherapy #treatmentofepilepsy
https://wn.com/Drug_Of_Choice_For_Various_Types_Of_Seizures_Anticonvulsant_Drugs_Pharmacology_Fmge_And_Neet_Pg
📌 𝐅𝐨𝐥𝐥𝐨𝐰 𝐨𝐧 𝐈𝐧𝐬𝐭𝐚𝐠𝐫𝐚𝐦:- https://www.instagram.com/drgbhanuprakash
📌𝗝𝗼𝗶𝗻 𝗢𝘂𝗿 𝗧𝗲𝗹𝗲𝗴𝗿𝗮𝗺 𝗖𝗵𝗮𝗻𝗻𝗲𝗹 𝗛𝗲𝗿𝗲:- https://t.me/bhanuprakashdr
📌𝗦𝘂𝗯𝘀𝗰𝗿𝗶𝗯𝗲 𝗧𝗼 𝗠𝘆 𝗠𝗮𝗶𝗹𝗶𝗻𝗴 𝗟𝗶𝘀𝘁:- https://linktr.ee/DrGBhanuprakash
Drug of choice For Various tyoes of Seizures - Pharmacology Fmge and Neet pg
Anticonvulsant drugs are classified as either classic or newer anticonvulsants. Newer anticonvulsants are usually better tolerated and have a broader therapeutic range than classic anticonvulsant drugs. The choice of drug is guided by the type of seizure. First-line treatment for focal seizures includes e.g., lamotrigine or levetiracetam, while valproate is used for generalized seizures. All anticonvulsants have dose-dependent side effects on the central nervous system such as somnolence and nausea, but some agents have more specific side effects (e.g., gingival hyperplasia caused by phenytoin).
Besides their importance in anti-epileptic therapy, anticonvulsants are also used for pain management (e.g., carbamazepine or gabapentin as coanalgesics) or as mood stabilizers in bipolar disorders (valproate).
#Anticonvulsants #drugofchoiceforseizures #anticonvulsant #anticonvulsantdrugs #antiepileptictherapy #treatmentofepilepsy
- published: 23 Dec 2019
- views: 8543
10:59
Mode of Action & SAR of Antiepileptic | Anticonvulsant || L- 13 Unit-4 Medicinal Chemistry -I
About this video -
Topic - Mode of Action & SAR of Antiepileptic | Anticonvulsant || L- 13 Unit-4 Medicinal Chemistry -I
Subject – Medicinal Chemistry
Ant...
About this video -
Topic - Mode of Action & SAR of Antiepileptic | Anticonvulsant || L- 13 Unit-4 Medicinal Chemistry -I
Subject – Medicinal Chemistry
Anti-Psychosis - Tricky Classification हसते हसते चुटकियो में याद - https://youtu.be/z6CJa5UTKvU
B.Pharm – 4th sem
D.Pharm- 2nd year
FOR B.PHARM, D.PHARM & M.PHARM STUDENTS
Hello Students
I am Anurag Jaiswal. I am working as Assistant Professor in a Pharmacy College and trainer in Vibgyor Laboratories.
By ANURAG JAISWAL
M.Pharm (GPAT Qualified)
For downloading pdf notes of this chapter on very easy language visit our website
Our Official Website
www.kclpharmacy.com
Facebook Page
https://www.facebook.com/anurag.jaiswal.1291
Youtube Channel
https://youtube.com/c/KclTutorial
Email-
[email protected]
Ask anything about this topic on comment section.About this video - Number =
https://wn.com/Mode_Of_Action_Sar_Of_Antiepileptic_|_Anticonvulsant_||_L_13_Unit_4_Medicinal_Chemistry_I
About this video -
Topic - Mode of Action & SAR of Antiepileptic | Anticonvulsant || L- 13 Unit-4 Medicinal Chemistry -I
Subject – Medicinal Chemistry
Anti-Psychosis - Tricky Classification हसते हसते चुटकियो में याद - https://youtu.be/z6CJa5UTKvU
B.Pharm – 4th sem
D.Pharm- 2nd year
FOR B.PHARM, D.PHARM & M.PHARM STUDENTS
Hello Students
I am Anurag Jaiswal. I am working as Assistant Professor in a Pharmacy College and trainer in Vibgyor Laboratories.
By ANURAG JAISWAL
M.Pharm (GPAT Qualified)
For downloading pdf notes of this chapter on very easy language visit our website
Our Official Website
www.kclpharmacy.com
Facebook Page
https://www.facebook.com/anurag.jaiswal.1291
Youtube Channel
https://youtube.com/c/KclTutorial
Email-
[email protected]
Ask anything about this topic on comment section.About this video - Number =
- published: 29 Apr 2020
- views: 9514
8:15
Anticonvulsants (antiepileptic drugs)
This is a brief summary of anticonvulsants, or medicines used to treat epilepsy.
I created this presentation with Google Slides.
Image were created or taken ...
This is a brief summary of anticonvulsants, or medicines used to treat epilepsy.
I created this presentation with Google Slides.
Image were created or taken from Wikimedia Commons
I created this video with the YouTube Video Editor.
ADDITIONAL TAGS:
Anticonvulsants
Drug
Mechanism of action
Modern approach
Other indications
Side effects (unique/notable listed first)
Interaction
Metab
Carbamazepine
Na+ channel blocker: binds inactive Na channel, extend inactivation
simple partial, complex partial, secondary generalized (narrow)
bipolar disorder, trigeminal neuralgia
Hyponatremia... bone marrow suppression; hepatotox; sedation; dizziness; n/v; double vision; ataxia; fetal malform; bone demineraliz; Stevens-Johnson syndrome
p450 induction
hepatic
Phenytoin
Na+ channel blocker: complex actions
simple partial, complex partial, secondary generalized (narrow)
n/a
Bone demineralization; gingival hyperplasia (long term use); hypotension, arrhythmias, tissue necrosis ( IV admin)... bone marrow suppression; hepatotox; sedation; dizziness; n/v; double vision; ataxia; fetal malform; Stevens-Johnson syndrome
p450 induction
hepatic
Lamotrigine
Na+ channel blocker: selective for excitatory neuron NT like glutamate
all seizure types (broad spectrum)
bipolar disorder; antidepressant effects
Stevens-Johnson syndrome (life threatening rash)... sedation; dizziness; n/v; double vision; ataxia; fetal malform; bone demineraliz; Stevens-Johnson syndrome
p450; OCPs decrease efficacy
hepatic
Ethosuximide
Ca2+ channel blocker (α subunit, T type, thalamic)
absence seizures (narrow spectrum)
n/a; just first line for absence seizures
sedation; dizziness; n/v; double vision; ataxia; fetal malform; bone demineraliz; Stevens-Johnson syndrome
n/a
hepatic
Phenobarbital
GABA antagonist: augments GABA receptor (Cl channel)
simple partial, complex partial, secondary generalized (narrow)
Tremors (similar to primidone for essential tremor)
Hyperactivity, addiction, sedation... bone marrow suppression; hepatotox; dizziness; n/v; double vision; ataxia; fetal malform; bone demineraliz; Stevens-Johnson syndrome
p450 induction
hepatic
Valproate
many: blocks Na, enhance GABA, block Ca
all seizure types (broad spectrum)
Migraine prophylaxis, bipolar disorder
fetal malformation (strongest teratogen); weight gain, tremor, hair loss, fulminant hepatic failure (limits use in kids); bone marrow suppression... sedation; dizziness; n/v; double vision; ataxia; fetal malform; bone demineraliz; Stevens-Johnson syndrome
p450 inhibitor
hepatic
Topiramate
many: blocks Na, enhance GABA, block glutamate (NMDA) receptor
all seizure types (broad spectrum)
Migraine prophylaxis
Cognitive impairment, weight loss, kidney stones... sedation; dizziness; n/v; double vision; ataxia; fetal malform; bone demineraliz; Stevens-Johnson syndrome
Decreases efficacy of OCPs
70:30 hepatic: renal
Gabapentin
unknown or partially known mechanism
simple partial, complex partial, secondary generalized (narrow)
Neuropathic pain, chronic pain
Ankle edema, weight gain... sedation; dizziness; n/v; double vision; ataxia; fetal malform; bone demineraliz; Stevens-Johnson syndrome
Antacids (limit bioavailability)
renal
Pregabalin
unknown or partially known mechanism
simple partial, complex partial, secondary generalized (narrow)
Neuropathic pain; fibromyalgia
Ankle edema, weight gain... sedation; dizziness; n/v; double vision; ataxia; fetal malform; bone demineraliz; Stevens-Johnson syndrome
Antacids (limit bioavailability)
renal
Levetiracetam
unknown or partially known mechanism
all seizure types (broad spectrum)
n/a
Depression, behavioral/psychiatric issues (up to 15%)... sedation; dizziness; n/v; double vision; ataxia; fetal malform; bone demineraliz; Stevens-Johnson syndrome
n/a
renal
https://wn.com/Anticonvulsants_(Antiepileptic_Drugs)
This is a brief summary of anticonvulsants, or medicines used to treat epilepsy.
I created this presentation with Google Slides.
Image were created or taken from Wikimedia Commons
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ADDITIONAL TAGS:
Anticonvulsants
Drug
Mechanism of action
Modern approach
Other indications
Side effects (unique/notable listed first)
Interaction
Metab
Carbamazepine
Na+ channel blocker: binds inactive Na channel, extend inactivation
simple partial, complex partial, secondary generalized (narrow)
bipolar disorder, trigeminal neuralgia
Hyponatremia... bone marrow suppression; hepatotox; sedation; dizziness; n/v; double vision; ataxia; fetal malform; bone demineraliz; Stevens-Johnson syndrome
p450 induction
hepatic
Phenytoin
Na+ channel blocker: complex actions
simple partial, complex partial, secondary generalized (narrow)
n/a
Bone demineralization; gingival hyperplasia (long term use); hypotension, arrhythmias, tissue necrosis ( IV admin)... bone marrow suppression; hepatotox; sedation; dizziness; n/v; double vision; ataxia; fetal malform; Stevens-Johnson syndrome
p450 induction
hepatic
Lamotrigine
Na+ channel blocker: selective for excitatory neuron NT like glutamate
all seizure types (broad spectrum)
bipolar disorder; antidepressant effects
Stevens-Johnson syndrome (life threatening rash)... sedation; dizziness; n/v; double vision; ataxia; fetal malform; bone demineraliz; Stevens-Johnson syndrome
p450; OCPs decrease efficacy
hepatic
Ethosuximide
Ca2+ channel blocker (α subunit, T type, thalamic)
absence seizures (narrow spectrum)
n/a; just first line for absence seizures
sedation; dizziness; n/v; double vision; ataxia; fetal malform; bone demineraliz; Stevens-Johnson syndrome
n/a
hepatic
Phenobarbital
GABA antagonist: augments GABA receptor (Cl channel)
simple partial, complex partial, secondary generalized (narrow)
Tremors (similar to primidone for essential tremor)
Hyperactivity, addiction, sedation... bone marrow suppression; hepatotox; dizziness; n/v; double vision; ataxia; fetal malform; bone demineraliz; Stevens-Johnson syndrome
p450 induction
hepatic
Valproate
many: blocks Na, enhance GABA, block Ca
all seizure types (broad spectrum)
Migraine prophylaxis, bipolar disorder
fetal malformation (strongest teratogen); weight gain, tremor, hair loss, fulminant hepatic failure (limits use in kids); bone marrow suppression... sedation; dizziness; n/v; double vision; ataxia; fetal malform; bone demineraliz; Stevens-Johnson syndrome
p450 inhibitor
hepatic
Topiramate
many: blocks Na, enhance GABA, block glutamate (NMDA) receptor
all seizure types (broad spectrum)
Migraine prophylaxis
Cognitive impairment, weight loss, kidney stones... sedation; dizziness; n/v; double vision; ataxia; fetal malform; bone demineraliz; Stevens-Johnson syndrome
Decreases efficacy of OCPs
70:30 hepatic: renal
Gabapentin
unknown or partially known mechanism
simple partial, complex partial, secondary generalized (narrow)
Neuropathic pain, chronic pain
Ankle edema, weight gain... sedation; dizziness; n/v; double vision; ataxia; fetal malform; bone demineraliz; Stevens-Johnson syndrome
Antacids (limit bioavailability)
renal
Pregabalin
unknown or partially known mechanism
simple partial, complex partial, secondary generalized (narrow)
Neuropathic pain; fibromyalgia
Ankle edema, weight gain... sedation; dizziness; n/v; double vision; ataxia; fetal malform; bone demineraliz; Stevens-Johnson syndrome
Antacids (limit bioavailability)
renal
Levetiracetam
unknown or partially known mechanism
all seizure types (broad spectrum)
n/a
Depression, behavioral/psychiatric issues (up to 15%)... sedation; dizziness; n/v; double vision; ataxia; fetal malform; bone demineraliz; Stevens-Johnson syndrome
n/a
renal
- published: 22 May 2016
- views: 60324
10:21
Anti epileptic Drugs / Anticonvulsants : Carbamazepine & Oxcarbamazepine : CNS Pharmacology
►𝐉𝐨𝐢𝐧 𝐓𝐡𝐢𝐬 𝐂𝐡𝐚𝐧𝐧𝐞𝐥 𝐓𝐨 𝐆𝐞𝐭 𝐀𝐜𝐜𝐞𝐬𝐬 𝐓𝐨 𝐏𝐞𝐫𝐤𝐬 :- https://bit.ly/2RQHvTN
💻 𝗔𝗰𝗰𝗲𝘀𝘀 𝟭𝟬𝟬+ 𝗵𝗼𝘂𝗿𝘀 𝗼𝗳 𝗣𝗵𝗮𝗿𝗺𝗮𝗰𝗼𝗹𝗼𝗴𝘆 𝘃𝗶𝗱𝗲𝗼 𝗹𝗲𝗰𝘁𝘂𝗿𝗲𝘀 𝘁𝗵𝗿𝗼𝘂𝗴𝗵 𝗺𝗲𝗱𝘃𝗶𝘇𝘇 𝗮𝗽𝗽
👉 𝗔𝗽𝗽 𝗟𝗶𝗻𝗸 :- https...
►𝐉𝐨𝐢𝐧 𝐓𝐡𝐢𝐬 𝐂𝐡𝐚𝐧𝐧𝐞𝐥 𝐓𝐨 𝐆𝐞𝐭 𝐀𝐜𝐜𝐞𝐬𝐬 𝐓𝐨 𝐏𝐞𝐫𝐤𝐬 :- https://bit.ly/2RQHvTN
💻 𝗔𝗰𝗰𝗲𝘀𝘀 𝟭𝟬𝟬+ 𝗵𝗼𝘂𝗿𝘀 𝗼𝗳 𝗣𝗵𝗮𝗿𝗺𝗮𝗰𝗼𝗹𝗼𝗴𝘆 𝘃𝗶𝗱𝗲𝗼 𝗹𝗲𝗰𝘁𝘂𝗿𝗲𝘀 𝘁𝗵𝗿𝗼𝘂𝗴𝗵 𝗺𝗲𝗱𝘃𝗶𝘇𝘇 𝗮𝗽𝗽
👉 𝗔𝗽𝗽 𝗟𝗶𝗻𝗸 :- https://bit.ly/3kbDWTO
👉 𝗖𝗼𝘂𝗿𝘀𝗲 𝗟𝗶𝗻𝗸 :- https://bit.ly/3hCYfbg
📌𝐅𝐨𝐥𝐥𝐨𝐰 𝐨𝐧 𝐈𝐧𝐬𝐭𝐚𝐠𝐫𝐚𝐦 :-
https://www.instagram.com/drgbhanuprakash
Anticonvulsant drugs are classified as either classic or newer anticonvulsants. Newer anticonvulsants are usually better tolerated and have a broader therapeutic range than classic anticonvulsant drugs. The choice of drug is guided by the type of seizure. First-line treatment for focal seizures includes e.g., lamotrigine or levetiracetam, while valproate is used for generalized seizures. All anticonvulsants have dose-dependent side effects on the central nervous system such as somnolence and nausea, but some agents have more specific side effects (e.g., gingival hyperplasia caused by phenytoin).
Besides their importance in anti-epileptic therapy, anticonvulsants are also used for pain management (e.g., carbamazepine or gabapentin as coanalgesics) or as mood stabilizers in bipolar disorders (valproate).
#Anticonvulsantdrugs #antiepilepticdrugs #anticonvulsants #antiepileptics #pharmacologyneetpg #pharmacologyusmle #pharmacologyfmge #pharmacology
https://wn.com/Anti_Epileptic_Drugs_Anticonvulsants_Carbamazepine_Oxcarbamazepine_Cns_Pharmacology
►𝐉𝐨𝐢𝐧 𝐓𝐡𝐢𝐬 𝐂𝐡𝐚𝐧𝐧𝐞𝐥 𝐓𝐨 𝐆𝐞𝐭 𝐀𝐜𝐜𝐞𝐬𝐬 𝐓𝐨 𝐏𝐞𝐫𝐤𝐬 :- https://bit.ly/2RQHvTN
💻 𝗔𝗰𝗰𝗲𝘀𝘀 𝟭𝟬𝟬+ 𝗵𝗼𝘂𝗿𝘀 𝗼𝗳 𝗣𝗵𝗮𝗿𝗺𝗮𝗰𝗼𝗹𝗼𝗴𝘆 𝘃𝗶𝗱𝗲𝗼 𝗹𝗲𝗰𝘁𝘂𝗿𝗲𝘀 𝘁𝗵𝗿𝗼𝘂𝗴𝗵 𝗺𝗲𝗱𝘃𝗶𝘇𝘇 𝗮𝗽𝗽
👉 𝗔𝗽𝗽 𝗟𝗶𝗻𝗸 :- https://bit.ly/3kbDWTO
👉 𝗖𝗼𝘂𝗿𝘀𝗲 𝗟𝗶𝗻𝗸 :- https://bit.ly/3hCYfbg
📌𝐅𝐨𝐥𝐥𝐨𝐰 𝐨𝐧 𝐈𝐧𝐬𝐭𝐚𝐠𝐫𝐚𝐦 :-
https://www.instagram.com/drgbhanuprakash
Anticonvulsant drugs are classified as either classic or newer anticonvulsants. Newer anticonvulsants are usually better tolerated and have a broader therapeutic range than classic anticonvulsant drugs. The choice of drug is guided by the type of seizure. First-line treatment for focal seizures includes e.g., lamotrigine or levetiracetam, while valproate is used for generalized seizures. All anticonvulsants have dose-dependent side effects on the central nervous system such as somnolence and nausea, but some agents have more specific side effects (e.g., gingival hyperplasia caused by phenytoin).
Besides their importance in anti-epileptic therapy, anticonvulsants are also used for pain management (e.g., carbamazepine or gabapentin as coanalgesics) or as mood stabilizers in bipolar disorders (valproate).
#Anticonvulsantdrugs #antiepilepticdrugs #anticonvulsants #antiepileptics #pharmacologyneetpg #pharmacologyusmle #pharmacologyfmge #pharmacology
- published: 06 Jan 2020
- views: 41795
18:55
Antiepileptic Drugs (Part 01)= General Introduction, Types and Classifications of Epilepsy (HINDI)
Download "Solution Pharmacy" Mobile App to Get All Uploaded Notes, Model Question Papers, Answer Papers, Online Test and other GPAT Materials - https://play.goo...
Download "Solution Pharmacy" Mobile App to Get All Uploaded Notes, Model Question Papers, Answer Papers, Online Test and other GPAT Materials - https://play.google.com/store/apps/details?id=co.bolton.nqilv
Free model question paper for pharmacology 01 (All units) –
https://drive.google.com/drive/folders/1d61HhxtPwkK3TqY2ZD45z_shGayyG3xO?usp=sharing
Free Pharmacology- 1 notes (made by students) –
https://drive.google.com/open?id=1PRaNYy7_a60FCIpDzKTIK4gxOLhBclFQ
Epilepsy is a central nervous system (neurological) disorder in which brain activity becomes abnormal, causing seizures or periods of unusual behaviour, sensations, and sometimes loss of awareness.
Seizure symptoms can vary widely. Some people with epilepsy simply stare blankly for a few seconds during a seizure, while others repeatedly twitch their arms or legs. Having a single seizure doesn't mean you have epilepsy. At least two unprovoked seizures are generally required for an epilepsy diagnosis.
Symptoms-
(1) Temporary confusion
(2) A staring spell
(3) Uncontrollable jerking movements of the arms and legs
(4) Loss of consciousness or awareness
(5) Psychic symptoms such as fear, anxiety or deja vu
Types of epilepsy- (1) Idiopathic (2) Symptomatic
Classification-
1- Simple Partial
2- Generalized-
(A) Absence seizures
(B) Tonic seizures. Tonic seizures cause stiffening of your muscles. These seizures usually affect muscles in your back, arms, and legs and may cause you to fall to the ground.
(C) Atonic seizures. Atonic seizures, also known as drop seizures, cause a loss of muscle control, which may cause you to suddenly collapse or fall down.
(D) Clonic seizures
(E)Myoclonic seizures
(F) Tonic-clonic seizures
Description credit- https://www.mayoclinic.org/diseases-conditions/epilepsy/symptoms-causes/syc-20350093
Get in touch with the solution by just clicking following links-
Facebook Page- https://www.facebook.com/pharmavideo/
Facebook Group- https://www.facebook.com/groups/solutionpharamcy
Instagram- https://www.instagram.com/solutionpharmacy/
Mail Us for Free Pharmacology Materials-
[email protected]
LinkedIn- http://linkedin.com/in/pushpendrakpatel
https://wn.com/Antiepileptic_Drugs_(Part_01)_General_Introduction,_Types_And_Classifications_Of_Epilepsy_(Hindi)
Download "Solution Pharmacy" Mobile App to Get All Uploaded Notes, Model Question Papers, Answer Papers, Online Test and other GPAT Materials - https://play.google.com/store/apps/details?id=co.bolton.nqilv
Free model question paper for pharmacology 01 (All units) –
https://drive.google.com/drive/folders/1d61HhxtPwkK3TqY2ZD45z_shGayyG3xO?usp=sharing
Free Pharmacology- 1 notes (made by students) –
https://drive.google.com/open?id=1PRaNYy7_a60FCIpDzKTIK4gxOLhBclFQ
Epilepsy is a central nervous system (neurological) disorder in which brain activity becomes abnormal, causing seizures or periods of unusual behaviour, sensations, and sometimes loss of awareness.
Seizure symptoms can vary widely. Some people with epilepsy simply stare blankly for a few seconds during a seizure, while others repeatedly twitch their arms or legs. Having a single seizure doesn't mean you have epilepsy. At least two unprovoked seizures are generally required for an epilepsy diagnosis.
Symptoms-
(1) Temporary confusion
(2) A staring spell
(3) Uncontrollable jerking movements of the arms and legs
(4) Loss of consciousness or awareness
(5) Psychic symptoms such as fear, anxiety or deja vu
Types of epilepsy- (1) Idiopathic (2) Symptomatic
Classification-
1- Simple Partial
2- Generalized-
(A) Absence seizures
(B) Tonic seizures. Tonic seizures cause stiffening of your muscles. These seizures usually affect muscles in your back, arms, and legs and may cause you to fall to the ground.
(C) Atonic seizures. Atonic seizures, also known as drop seizures, cause a loss of muscle control, which may cause you to suddenly collapse or fall down.
(D) Clonic seizures
(E)Myoclonic seizures
(F) Tonic-clonic seizures
Description credit- https://www.mayoclinic.org/diseases-conditions/epilepsy/symptoms-causes/syc-20350093
Get in touch with the solution by just clicking following links-
Facebook Page- https://www.facebook.com/pharmavideo/
Facebook Group- https://www.facebook.com/groups/solutionpharamcy
Instagram- https://www.instagram.com/solutionpharmacy/
Mail Us for Free Pharmacology Materials-
[email protected]
LinkedIn- http://linkedin.com/in/pushpendrakpatel
- published: 12 May 2019
- views: 212893
28:13
Anticonvulsant drugs structure and IUPAC names Antiepileptic drugs
Adrenergic drugs: https://www.youtube.com/watch?v=wUn1BjXY63o
Antiadrenergic drugs: https://www.youtube.com/watch?v=6S5MUc5F37A
Metabolism of catecholamines: ht...
Adrenergic drugs: https://www.youtube.com/watch?v=wUn1BjXY63o
Antiadrenergic drugs: https://www.youtube.com/watch?v=6S5MUc5F37A
Metabolism of catecholamines: https://www.youtube.com/watch?v=R6ddwyVmZq4
Cholinergic drugs: https://www.youtube.com/watch?v=KM11NReVn8k
Anticholinergic drugs: https://www.youtube.com/watch?v=cUOBOU9lL3M
Sedatives and Hypnotics: https://www.youtube.com/watch?v=b7iR8pgOEYs
Antipsychotic drugs: https://www.youtube.com/watch?v=5t77q-0Wz2M
https://wn.com/Anticonvulsant_Drugs_Structure_And_Iupac_Names_Antiepileptic_Drugs
Adrenergic drugs: https://www.youtube.com/watch?v=wUn1BjXY63o
Antiadrenergic drugs: https://www.youtube.com/watch?v=6S5MUc5F37A
Metabolism of catecholamines: https://www.youtube.com/watch?v=R6ddwyVmZq4
Cholinergic drugs: https://www.youtube.com/watch?v=KM11NReVn8k
Anticholinergic drugs: https://www.youtube.com/watch?v=cUOBOU9lL3M
Sedatives and Hypnotics: https://www.youtube.com/watch?v=b7iR8pgOEYs
Antipsychotic drugs: https://www.youtube.com/watch?v=5t77q-0Wz2M
- published: 31 Mar 2020
- views: 13437
8:39
Pharmacology - Seizures (Epilepsy) drugs for nursing RN PN NCLEX
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🚨LIMITED TIME OFFER!🚨
In Nursing School? Get access to FREE exclusive content here! → https://bit.ly/44Jyn2K
Try our NCLEX Prep entirely FREE here! → https://bit.ly/45KTYZI
SimpleNursing memberships have 1,200+ animated videos, 900+ colorful study guides, 3,000+ practice questions, and more! See why SimpleNursing is trusted by over 1,000,000 nursing students.
Today’s video is all about epilepsy anticonvulsant drugs for Nursing Students and NCLEX Review.
Anticonvulsant drugs are used to treat seizures (from epilepsy), which are sudden abnormal electrical discharges from nerve cells in the brain. These drugs help prevent brain seizures by blocking the spread of neuronal activity that causes them.
The most common anticonvulsant drugs include Levetiracetam and Phenytoin – and both have different interactions and required nursing interventions.
#NCLEX #pharmacology
#Epilepsy #Seizures #RN #registerednurse
https://wn.com/Pharmacology_Seizures_(Epilepsy)_Drugs_For_Nursing_Rn_Pn_Nclex
🚨LIMITED TIME OFFER!🚨
In Nursing School? Get access to FREE exclusive content here! → https://bit.ly/44Jyn2K
Try our NCLEX Prep entirely FREE here! → https://bit.ly/45KTYZI
SimpleNursing memberships have 1,200+ animated videos, 900+ colorful study guides, 3,000+ practice questions, and more! See why SimpleNursing is trusted by over 1,000,000 nursing students.
Today’s video is all about epilepsy anticonvulsant drugs for Nursing Students and NCLEX Review.
Anticonvulsant drugs are used to treat seizures (from epilepsy), which are sudden abnormal electrical discharges from nerve cells in the brain. These drugs help prevent brain seizures by blocking the spread of neuronal activity that causes them.
The most common anticonvulsant drugs include Levetiracetam and Phenytoin – and both have different interactions and required nursing interventions.
#NCLEX #pharmacology
#Epilepsy #Seizures #RN #registerednurse
- published: 22 Feb 2021
- views: 193412