The evolution of spliced leader trans-splicing in nematodes
- PMID: 20659016
- DOI: 10.1042/BST0381125
The evolution of spliced leader trans-splicing in nematodes
Abstract
Spliced leader trans-splicing occurs in many primitive eukaryotes including nematodes. Most of our knowledge of trans-splicing in nematodes stems from the model organism Caenorhabditis elegans and relatives, and from work with Ascaris. Our investigation of spliced leader trans-splicing in distantly related Dorylaimia nematodes indicates that spliced-leader trans-splicing arose before the nematode phylum and suggests that the spliced leader RNA gene complements in extant nematodes have evolved from a common ancestor with a diverse set of spliced leader RNA genes.
Similar articles
-
Operon structure and trans-splicing in the nematode Pristionchus pacificus.Mol Biol Evol. 2003 Dec;20(12):2097-103. doi: 10.1093/molbev/msg225. Epub 2003 Aug 29. Mol Biol Evol. 2003. PMID: 12949121
-
Spliced leader RNA-mediated trans-splicing in phylum Rotifera.Mol Biol Evol. 2005 Jun;22(6):1482-9. doi: 10.1093/molbev/msi139. Epub 2005 Mar 23. Mol Biol Evol. 2005. PMID: 15788744
-
Operon conservation and the evolution of trans-splicing in the phylum Nematoda.PLoS Genet. 2006 Nov 24;2(11):e198. doi: 10.1371/journal.pgen.0020198. Epub 2006 Oct 9. PLoS Genet. 2006. PMID: 17121468 Free PMC article.
-
Nematode spliced leaders--ubiquity, evolution and utility.Int J Parasitol. 1996 Oct;26(10):1025-33. Int J Parasitol. 1996. PMID: 8982784 Review.
-
Trans-splicing.Wiley Interdiscip Rev RNA. 2011 May-Jun;2(3):417-34. doi: 10.1002/wrna.71. Epub 2011 Jan 20. Wiley Interdiscip Rev RNA. 2011. PMID: 21957027 Review.
Cited by
-
U6 snRNA m6A modification is required for accurate and efficient splicing of C. elegans and human pre-mRNAs.Nucleic Acids Res. 2024 Aug 27;52(15):9139-9160. doi: 10.1093/nar/gkae447. Nucleic Acids Res. 2024. PMID: 38808663 Free PMC article.
-
A diversified and segregated mRNA spliced-leader system in the parasitic Perkinsozoa.Open Biol. 2022 Aug;12(8):220126. doi: 10.1098/rsob.220126. Epub 2022 Aug 24. Open Biol. 2022. PMID: 36000319 Free PMC article.
-
SLFinder, a pipeline for the novel identification of splice-leader sequences: a good enough solution for a complex problem.BMC Bioinformatics. 2020 Jul 8;21(1):293. doi: 10.1186/s12859-020-03610-6. BMC Bioinformatics. 2020. PMID: 32640978 Free PMC article.
-
An in vivo genetic screen for genes involved in spliced leader trans-splicing indicates a crucial role for continuous de novo spliced leader RNP assembly.Nucleic Acids Res. 2017 Aug 21;45(14):8474-8483. doi: 10.1093/nar/gkx500. Nucleic Acids Res. 2017. PMID: 28582530 Free PMC article.
-
Co-evolution of SNF spliceosomal proteins with their RNA targets in trans-splicing nematodes.Genetica. 2016 Aug;144(4):487-96. doi: 10.1007/s10709-016-9918-x. Epub 2016 Jul 22. Genetica. 2016. PMID: 27450547
Publication types
MeSH terms
Substances
Grants and funding
LinkOut - more resources
Full Text Sources