PTPRD

PTPRD
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1X5Z, 2DLH, 2YD6, 2YD7, 4RCA
Dynodwyr
Cyfenwau	PTPRD, HPTP, HPTPD, HPTPDELTA, PTPD, RPTPDELTA, protein tyrosine phosphatase, receptor type D, protein tyrosine phosphatase receptor type D, R-PTP-delta
Dynodwyr allanol	OMIM: 601598 HomoloGene: 88669 GeneCards: PTPRD
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • transmembrane receptor protein tyrosine phosphatase activity • phosphoprotein phosphatase activity • protein tyrosine phosphatase activity • hydrolase activity • signaling receptor binding • cell adhesion molecule binding • GO:0098519, GO:0098518 phosphatase activity • GO:0001948, GO:0016582 protein binding Cydrannau o'r gell • extracellular exosome • bilen • integral component of membrane • integral component of plasma membrane • Cellbilen • glutamatergic synapse Prosesau biolegol • presynaptic membrane assembly • transmembrane receptor protein tyrosine phosphatase signaling pathway • neuron differentiation • positive regulation of dendrite morphogenesis • GO:0016576 protein dephosphorylation • phosphate-containing compound metabolic process • heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules • GO:0098501, GO:0098502, GO:0006286 dephosphorylation • peptidyl-tyrosine dephosphorylation • positive regulation of synapse assembly • regulation of postsynaptic density assembly • trans-synaptic signaling by trans-synaptic complex • synaptic membrane adhesion • regulation of presynapse assembly Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	5789	n/a
Ensembl	ENSG00000153707 ENSG00000282932	n/a
UniProt	P23468 Q3KPI9	n/a
RefSeq (mRNA)	NM_001040712 NM_001171025 NM_002839 NM_130391 NM_130392 NM_130393 NM_001377946 NM_001377947 NM_001377958 NM_001378058	n/a
RefSeq (protein)	NP_001035802 NP_001164496 NP_002830 NP_569075 NP_569076 NP_569077 NP_001364875 NP_001364876 NP_001364887 NP_001364987 NP_569077.2	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn PTPRD yw PTPRD a elwir hefyd yn PTPRD protein (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 9, band 9p24.1-p23.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn PTPRD.

• HPTP
• PTPD
• HPTPD
• HPTPDELTA
• RPTPDELTA

Llyfryddiaeth

• "PTPRD gene associated with blood pressure response to atenolol and resistant hypertension. ". J Hypertens. 2015. PMID 26425837.
• "Loss-of-Function PTPRD Mutations Lead to Increased STAT3 Activation and Sensitivity to STAT3 Inhibition in Head and Neck Cancer. ". PLoS One. 2015. PMID 26267899.
• "Recurrent epigenetic silencing of the PTPRD tumor suppressor in laryngeal squamous cell carcinoma. ". Tumour Biol. 2017. PMID 28345455.
• "Genome-Wide Association Study Suggested the PTPRD Polymorphisms Were Associated With Weight Gain Effects of Atypical Antipsychotic Medications. ". Schizophr Bull. 2016. PMID 26656879.
• "Protein tyrosine phosphatases receptor type D is a potential tumour suppressor gene inactivated by deoxyribonucleic acid methylation in paediatric acute myeloid leukaemia.". Acta Paediatr. 2016. PMID 26607758.