Sertraline
Guā-māu
Clinical data | |
---|---|
Trade names | Zoloft (左洛復), 彼邁樂 , Lustral téng[1] |
AHFS/Drugs.com | Monograph |
MedlinePlus | a697048 |
Pregnancy category | |
Routes of administration | kháu-ho̍k |
ATC code | |
Legal status | |
Legal status | |
Pharmacokinetic data | |
Bioavailability | 44% |
Protein binding | 98.5% |
Metabolism | koaⁿ-chōng[2] |
Elimination half-life | ~23-26 tiám-cheng (Ke hoa̍t-sèng ê tāi-siā sán-bu̍t Norsertraline sī 66 tiám-cheng)[3][4] |
Excretion | jiō-e̍k |
Identifiers | |
| |
CAS Number | |
PubChem CID | |
DrugBank | |
ChemSpider | |
UNII | |
KEGG | |
ChEBI | |
ChEMBL | |
Chemical and physical data | |
Formula | C17H17Cl2N |
Molar mass | 306.229 g/mol |
3D model (JSmol) | |
| |
| |
(verify) |
Sertraline mā kiò chò Sià-khiok-lîm (舍曲林) , ia̍h ū Zoloft ê siong-phín miâ, sī chi̍t chióng sóan-te̍k-sèng huih-chheng-sò͘ chài-liap-chhú ek-chè-chè lūi ê khòng ek-ut io̍h-bu̍t, tī 1991 nî iû Pfizer chè-io̍h kong-su hoat-bêng.
Sèng-chit
[siu-kái | kái goân-sí-bé]Sertraline sī pe̍h-sek, bâ-bui iûⁿ î chúi ê kiat-chiⁿ.
- ↑ drugs.com drugs.com international Sertraline Page accessed May 11, 2015
- ↑ Obach RS, Cox LM, Tremaine LM (2005). "Sertraline is metabolized by multiple cytochrome P450 enzymes, monoamine oxidases, and glucuronyl transferases in human: an in vitro study". Drug Metab. Dispos. 33 (2): 262–70. doi:10.1124/dmd.104.002428. PMID 15547048.
- ↑ Sertraline FDA Label. http://www.fda.gov/ohrms/dockets/ac/04/briefing/4006b1_06_zoloft-label.pdf
- ↑ Brunton L, Chabner B, Knollman B. Goodman and Gilman’s The Pharmacological Basis of Therapeutics, Twelfth Edition. McGraw Hill Professional; 2010.