Wikidata:Property proposal/facilitates flow of
facilitates flow of / transports / channel for /enables flow of / carries
[edit]Originally proposed at Wikidata:Property proposal/Natural science
| Description | The cargo/substrate actively transported or passively channeled by a protein. |
|---|---|
| Data type | Item |
| Domain | item; preferably instances of or subclasses of protein (Q8054) or protein-containing complex (Q22325163) or group or class of proteins (Q84467700) or protein family (Q417841) |
| Example 1 | Cu(+) exporting P-type ATPase;soluble Cu(+) chaperone b0484 (Q23087199) --> copper (Q753) |
| Example 2 | glutamate transporter (Q5419641) --> L-glutamate(1−) (Q27104095) |
| Example 3 | chloride channel (Q106916978) --> chloride ion (Q108200) |
| Example 4 | solute carrier family 6 member 4 (Q410142) --> serotonin (Q167934) |
| Planned use | Connecting channels and other proteins to their substrates. |
| Expected completeness | always incomplete (Q21873886) |
Motivation
[edit]Currently, channels are not linked to their substrates. For example, always incomplete (Q21873886) is not currently linked to sodium sodium (Q658). That makes it impossible to query for channels of a particular compound type. Such queries would be very useful for biology/biomedicine enthusiasts using Wikidata.
Multiple synonyms are provided as the property is expected to account for different ways in which proteins (or other macromolecules) carry substances across compartments. TiagoLubiana (talk) 17:43, 21 December 2021 (UTC)
Discussion
[edit]
WikiProject Molecular biology has more than 50 participants and couldn't be pinged. Please post on the WikiProject's talk page instead. -- TiagoLubiana (talk) 17:55, 21 December 2021 (UTC)
Support An important property to add. Coming from the channel field, I'm not 100% satisfied by the description though. Channels don't "transport." And "facilitates" sounds a lot like "catalyzes," which channels also don't do. What about being more explicit, e.g., "The cargo/substrate actively transported or passively channeled by a protein." AlexanderPico (talk) 20:16, 21 December 2021 (UTC)
- @AlexanderPico: Good suggestions. I have changed the description. Do you have a suggestion for a main label? Perhaps "mediates flux of" works better. I'm struggling to find a way to include transporters and channels. TiagoLubiana (talk) 17:38, 22 December 2021 (UTC)
- Thanks! Both "facilitates" and "mediates" sound about the same to me. Here are a couple others to consider, but I don't have strong opinion: "controls" or "regulates". AlexanderPico (talk) 20:04, 30 December 2021 (UTC)
- @AlexanderPico: Good suggestions. I have changed the description. Do you have a suggestion for a main label? Perhaps "mediates flux of" works better. I'm struggling to find a way to include transporters and channels. TiagoLubiana (talk) 17:38, 22 December 2021 (UTC)
- Support Did you already write a shape expression? --Egon Willighagen (talk) 07:49, 22 December 2021 (UTC)
- @Egon Willighagen: Not yet! Good suggestion, I've added to my to do list TiagoLubiana (talk) 17:38, 22 December 2021 (UTC)
- Support — MasterRus21thCentury (talk) 17:24, 1 January 2022 (UTC)
- @TiagoLubiana, AlexanderPico, Egon Willighagen, MasterRus21thCentury:
WikiProject Molecular biology has more than 50 participants and couldn't be pinged. Please post on the WikiProject's talk page instead. 
Done as facilitates flow of (P10228). UWashPrincipalCataloger (talk) 00:14, 2 January 2022 (UTC)
