Vinculin (Q424042)

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mammalian protein found in Homo sapiens
  • epididymis secretory sperm binding protein
  • epididymis luminal protein 114
  • vinculin
  • metavinculin
  • VCL
  • meta-vinculin
  • MV
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    English
    Vinculin
    mammalian protein found in Homo sapiens
    • epididymis secretory sperm binding protein
    • epididymis luminal protein 114
    • vinculin
    • metavinculin
    • VCL
    • meta-vinculin
    • MV

    Statements

    molecular function
    protein binding
    determination method or standard
    IPI
    17 references
    retrieved
    31 October 2017
    stated in
    Vinexin: a novel vinculin-binding protein with multiple SH3 domains enhances actin cytoskeletal organization
    GOA
    curator
    UniProt
    UniProt protein ID
    P18206
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206
    determination method or standard
    IPI
    retrieved
    31 October 2017
    stated in
    Human alpha-synemin interacts directly with vinculin and metavinculin
    GOA
    curator
    UniProt
    UniProt protein ID
    P18206
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206
    determination method or standard
    IPI
    retrieved
    31 October 2017
    stated in
    Integrin-mediated cell adhesion: the cytoskeletal connection
    GOA
    curator
    UniProt
    UniProt protein ID
    P18206
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206
    determination method or standard
    IPI
    retrieved
    31 October 2017
    stated in
    RNA and RNA binding proteins participate in early stages of cell spreading through spreading initiation centers
    GOA
    curator
    UniProt
    UniProt protein ID
    P18206
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206
    determination method or standard
    IPI
    retrieved
    31 October 2017
    stated in
    Structural dynamics of alpha-actinin-vinculin interactions
    GOA
    curator
    UniProt
    UniProt protein ID
    P18206
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206
    determination method or standard
    IPI
    retrieved
    31 October 2017
    stated in
    Structural basis for amplifying vinculin activation by talin
    GOA
    curator
    UniProt
    UniProt protein ID
    P18206
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206
    determination method or standard
    IPI
    retrieved
    31 October 2017
    stated in
    KIAA1797/FOCAD encodes a novel focal adhesion protein with tumour suppressor function in gliomas
    GOA
    curator
    UniProt
    UniProt protein ID
    P18206
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206
    determination method or standard
    IPI
    retrieved
    31 October 2017
    stated in
    Monocyte cells and cancer cells express novel paxillin isoforms with different binding properties to focal adhesion proteins
    GOA
    curator
    UniProt
    UniProt protein ID
    P18206
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206
    determination method or standard
    IPI
    retrieved
    31 October 2017
    stated in
    Dimer asymmetry defines α-catenin interactions
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206
    determination method or standard
    IPI
    retrieved
    31 October 2017
    stated in
    Raver1 Interactions with Vinculin and RNA Suggest a Feed-Forward Pathway in Directing mRNA to Focal Adhesions
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206
    determination method or standard
    IPI
    retrieved
    31 October 2017
    stated in
    Recruitment of the Arp2/3 complex to vinculin: coupling membrane protrusion to matrix adhesion
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206
    determination method or standard
    IPI
    retrieved
    31 October 2017
    stated in
    Capping of actin filaments by vinculin activated by the Shigella IpaA carboxyl-terminal domain
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206
    determination method or standard
    IPI
    retrieved
    31 October 2017
    stated in
    Vinculin binding in its closed conformation by a helix addition mechanism
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206
    determination method or standard
    IPI
    retrieved
    31 October 2017
    stated in
    Structural mimicry for vinculin activation by IpaA, a virulence factor of Shigella flexneri
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206
    determination method or standard
    IPI
    retrieved
    31 October 2017
    stated in
    A proteome-scale map of the human interactome network
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206
    determination method or standard
    IPI
    retrieved
    31 October 2017
    stated in
    CAP interacts with cytoskeletal proteins and regulates adhesion-mediated ERK activation and motility
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206
    determination method or standard
    IPI
    retrieved
    31 October 2017
    stated in
    Role of dystrophins and utrophins in platelet adhesion process
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206
    determination method or standard
    IPI
    cell component
    focal adhesion
    determination method or standard
    IDA
    ISS
    IEA
    6 references
    retrieved
    31 October 2017
    stated in
    GOA
    curator
    UniProt
    UniProt protein ID
    P18206
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206
    determination method or standard
    ISS
    retrieved
    31 October 2017
    stated in
    GOA
    curator
    UniProt
    UniProt protein ID
    P18206
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206
    determination method or standard
    IEA
    retrieved
    31 October 2017
    stated in
    GOA
    curator
    Ensembl genome database project
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206
    determination method or standard
    IEA
    retrieved
    31 October 2017
    stated in
    Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation
    GOA
    curator
    UniProt
    UniProt protein ID
    P18206
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206
    determination method or standard
    IDA
    retrieved
    31 October 2017
    stated in
    GOA
    curator
    Human Protein Atlas
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206
    determination method or standard
    IDA
    retrieved
    31 October 2017
    stated in
    Vinculin regulates cell-surface E-cadherin expression by binding to beta-catenin
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206
    determination method or standard
    IDA
    biological process
    Gene Atlas image
    PBB GE VCL 200931 s at fs.png
    732 × 530; 11 KB
    0 references

    Identifiers

    PDB structure ID
     
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