Transforming growth factor beta-independent shuttling of Smad4 between the cytoplasm and nucleus. (Q39457117)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11074002%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

title

Transforming growth factor beta-independent shuttling of Smad4 between the cytoplasm and nucleus (English)

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1 November 2019

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3

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1 November 2019

Francisco José Nicolás

series ordinal

2

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1 November 2019

author name string

C E Pierreux

series ordinal

1

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1 November 2019

language of work or name

English

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publication date

1 December 2000

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Molecular and Cellular Biology

1 November 2019

published in

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1 November 2019

volume

20

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1 November 2019

issue

23

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1 November 2019

page(s)

9041-9054

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Importin beta mediates nuclear translocation of Smad 3

1 November 2019

cites work

1 reference

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12 September 2017

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12 September 2017

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Signaling inputs converge on nuclear effectors in TGF-beta signaling

12 September 2017

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OAZ uses distinct DNA- and protein-binding zinc fingers in separate BMP-Smad and Olf signaling pathways

12 September 2017

1 reference

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The Smad4 activation domain (SAD) is a proline-rich, p300-dependent transcriptional activation domain

12 September 2017

1 reference

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Transport between the cell nucleus and the cytoplasm

12 September 2017

1 reference

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Regulation of nuclear localization: a key to a door

12 September 2017

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Cortical actin organization: lessons from ERM (ezrin/radixin/moesin) proteins

12 September 2017

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SnoN and Ski protooncoproteins are rapidly degraded in response to transforming growth factor beta signaling

12 September 2017

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Negative feedback regulation of TGF-beta signaling by the SnoN oncoprotein

12 September 2017

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A SMAD ubiquitin ligase targets the BMP pathway and affects embryonic pattern formation

12 September 2017

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Signal-regulated activation of serum response factor is mediated by changes in actin dynamics

12 September 2017

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Nuclear localization of the p120(ctn) Armadillo-like catenin is counteracted by a nuclear export signal and by E-cadherin expression

12 September 2017

1 reference

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A mechanism of repression of TGFbeta/ Smad signaling by oncogenic Ras

12 September 2017

1 reference

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Smad3-Smad4 and AP-1 complexes synergize in transcriptional activation of the c-Jun promoter by transforming growth factor beta

12 September 2017

1 reference

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SARA, a FYVE domain protein that recruits Smad2 to the TGFbeta receptor

12 September 2017

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TGF-beta signal transduction

12 September 2017

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Smads and early developmental signaling by the TGFbeta superfamily

12 September 2017

1 reference

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Dual role of the Smad4/DPC4 tumor suppressor in TGFbeta-inducible transcriptional complexes

12 September 2017

1 reference

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Opposing BMP and EGF signalling pathways converge on the TGF-β family mediator Smad1

12 September 2017

1 reference

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The DAF-3 Smad protein antagonizes TGF-β-related receptor signaling in the Caenorhabditis elegansdauer pathway

12 September 2017

1 reference

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TGF-beta receptor-mediated signalling through Smad2, Smad3 and Smad4

12 September 2017

1 reference

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Smad4 and FAST-1 in the assembly of activin-responsive factor

12 September 2017

1 reference

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Characterization of functional domains within Smad4/DPC4

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86557

DPC4 (SMAD4) mediates transforming growth factor-beta1 (TGF-beta1) induced growth inhibition and transcriptional response in breast tumour cells

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86557

Nucleocytoplasmic transport: signals, mechanisms and regulation

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86557

Heteromeric and homomeric interactions correlate with signaling activity and functional cooperativity of Smad3 and Smad4/DPC4

12 September 2017

1 reference

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A transcriptional partner for MAD proteins in TGF-beta signalling

12 September 2017

1 reference

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DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1

12 September 2017

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Leptomycin B targets a regulatory cascade of crm1, a fission yeast nuclear protein, involved in control of higher order chromosome structure and gene expression

12 September 2017

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GS domain mutations that constitutively activate T beta R-I, the downstream signaling component in the TGF-beta receptor complex

12 September 2017

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The Rho family GTPases RhoA, Rac1, and CDC42Hs regulate transcriptional activation by SRF

12 September 2017

1 reference

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Activation of the human beta-interferon gene requires an interferon-inducible factor

12 September 2017

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Nuclear targeting sequences--a consensus?

12 September 2017

1 reference

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Homeodomain and winged-helix transcription factors recruit activated Smads to distinct promoter elements via a common Smad interaction motif

12 September 2017

1 reference

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Ubiquitin-dependent degradation of TGF-beta-activated smad2.

14 September 2017

1 reference

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Nuclear trafficking of Cubitus interruptus in the transcriptional regulation of Hedgehog target gene expression

25 September 2017

1 reference

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Alternatively spliced variant of Smad2 lacking exon 3. Comparison with wild-type Smad2 and Smad3.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86557

Identification of a potential regulator of early transcriptional responses to mesoderm inducers in the frog embryo.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86557

An N-terminal nuclear export signal is required for the nucleocytoplasmic shuttling of IkappaBalpha

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86557

Identification and functional characterization of a Smad binding element (SBE) in the JunB promoter that acts as a transforming growth factor-beta, activin, and bone morphogenetic protein-inducible enhancer

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86557

Mutations increasing autoinhibition inactivate tumour suppressors Smad2 and Smad4

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86557

SMAD destruction turns off signalling

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86557

Xenopus Smad4beta is the co-Smad component of developmentally regulated transcription factor complexes responsible for induction of early mesodermal genes.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86557

Identification of two Smad4 proteins in Xenopus. Their common and distinct properties

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86557

Abrogation of TGFbeta signaling in T cells leads to spontaneous T cell differentiation and autoimmune disease

21 August 2018

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12 December 2020

DPC4 gene in various tumor types

1 reference

12 December 2020

mRNA Profiling of Rat Islet Tumors Reveals Nkx 6.1 as a β-Cell-specific Homeodomain Transcription Factor

1 reference

12 December 2020

DPC4 splice variants in neuroblastoma

1 reference

12 December 2020

10.1128/MCB.20.23.9041-9054.2000

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11074002%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11074002%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

PubMed publication ID

11074002

1 reference