POU domain, class 4, transcription factor 3 (Q21986680)

Lambda repressor-like, DNA-binding domain superfamily

1 reference

Homeobox-like domain superfamily

1 reference

Homeobox domain, protein family

1 reference

POU domain, protein family

1 reference

POU-specific domain, protein family

1 reference

Cro/C1-type helix-turn-helix domain, protein family

1 reference

Homeobox, conserved site, protein family

1 reference

1 reference

25 May 2022

1 reference

25 May 2022

DNA-binding transcription activator activity, RNA polymerase II-specific

3 references

4 references

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q63955&geneProductId=UniProtKB:Q63955

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q63955&geneProductId=UniProtKB:Q63955

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63955

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63955

sequence-specific DNA binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63955

3 references

14 February 2019

14 February 2019

The opposite and antagonistic effects of the closely related POU family transcription factors Brn-3a and Brn-3b on the activity of a target promoter are dependent on differences in the POU domain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63955

14 February 2019

Mouse Brn-3 family of POU transcription factors: a new aminoterminal domain is crucial for the oncogenic activity of Brn-3a

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63955

protein binding

IPI

1 reference

14 February 2019

Isl1 and Pou4f2 form a complex to regulate target genes in developing retinal ganglion cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63955

RNA polymerase II cis-regulatory region sequence-specific DNA binding

IPI

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q63955&geneProductId=UniProtKB:Q63955

DNA-binding transcription activator activity, RNA polymerase II-specific

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q63955&geneProductId=UniProtKB:Q63955

transcription regulator complex

cell component

IC

1 reference

14 February 2019

Brn-3c (POU4F3) regulates BDNF and NT-3 promoter activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63955

IC

nucleus

6 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63955

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63955

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63955

14 February 2019

The Brn-3 family of POU-domain factors: primary structure, binding specificity, and expression in subsets of retinal ganglion cells and somatosensory neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63955

14 February 2019

Essential role of POU–domain factor Brn-3c in auditory and vestibular hair cell development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63955

14 February 2019

Requirement for Brn-3c in maturation and survival, but not in fate determination of inner ear hair cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63955

cytoplasm

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63955

4 references

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63955

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63955

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63955

nucleoplasm

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q63955&geneProductId=UniProtKB:Q63955

biological process

neuron apoptotic process

1 reference

14 February 2019

Requirement for Brn-3c in maturation and survival, but not in fate determination of inner ear hair cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63955

vestibulocochlear nerve development

1 reference

14 February 2019

Brn3c null mutant mice show long-term, incomplete retention of some afferent inner ear innervation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63955

axon extension

1 reference

14 February 2019

Brn3b/Brn3c double knockout mice reveal an unsuspected role for Brn3c in retinal ganglion cell axon outgrowth

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63955

inner ear auditory receptor cell differentiation

inner ear morphogenesis

1 reference

14 February 2019

Brn3c null mutant mice show long-term, incomplete retention of some afferent inner ear innervation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63955

regulation of transcription by RNA polymerase II

1 reference

14 February 2019

Brn-3c (POU4F3) regulates BDNF and NT-3 promoter activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63955

regulation of transcription, DNA-templated

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63955

1 reference

14 February 2019

inner ear receptor cell differentiation

retinal ganglion cell axon guidance

1 reference

14 February 2019

Brn3b/Brn3c double knockout mice reveal an unsuspected role for Brn3c in retinal ganglion cell axon outgrowth

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63955

neuromuscular process controlling balance

Essential role of POU–domain factor Brn-3c in auditory and vestibular hair cell development

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63955

14 February 2019

Role of transcription factors Brn-3.1 and Brn-3.2 in auditory and visual system development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63955

14 February 2019

Brn3b/Brn3c double knockout mice reveal an unsuspected role for Brn3c in retinal ganglion cell axon outgrowth

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63955

hearing

Essential role of POU–domain factor Brn-3c in auditory and vestibular hair cell development

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63955

14 February 2019

Role of transcription factors Brn-3.1 and Brn-3.2 in auditory and visual system development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63955

14 February 2019

Brn3b/Brn3c double knockout mice reveal an unsuspected role for Brn3c in retinal ganglion cell axon outgrowth

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63955

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63955

14 February 2019

inner ear development

Essential role of POU–domain factor Brn-3c in auditory and vestibular hair cell development

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63955

14 February 2019

Requirement for Brn-3c in maturation and survival, but not in fate determination of inner ear hair cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63955

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63955

14 February 2019

transcription by RNA polymerase II

1 reference

16 July 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q63955&geneProductId=UniProtKB:Q63955

positive regulation of transcription by RNA polymerase II

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63955

14 February 2019

The opposite and antagonistic effects of the closely related POU family transcription factors Brn-3a and Brn-3b on the activity of a target promoter are dependent on differences in the POU domain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63955

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63955

transcription, DNA-templated

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q63955&geneProductId=UniProtKB:Q63955

1 reference

16 July 2018

cell differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63955

1 reference

14 February 2019

positive regulation of transcription by RNA polymerase II

1 reference

Homeobox, conserved site

1 reference

POU-specific domain

1 reference

POU domain

1 reference

Cro/C1-type helix-turn-helix domain

1 reference