CD44 antigen (Q21495004)

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mammalian protein found in Mus musculus
  • lymphocyte antigen 24
  • Cd44
  • phagocytic glycoprotein I
  • PGP-1
  • ECMR-III
  • HUTCH-I
  • extracellular matrix receptor III
  • GP90 lymphocyte homing/adhesion receptor
  • Ly-24
  • phagocytic glycoprotein 1
  • PGP-I
  • hermes antigen
  • hyaluronate receptor
edit
Language Label Description Also known as
English
CD44 antigen
mammalian protein found in Mus musculus
  • lymphocyte antigen 24
  • Cd44
  • phagocytic glycoprotein I
  • PGP-1
  • ECMR-III
  • HUTCH-I
  • extracellular matrix receptor III
  • GP90 lymphocyte homing/adhesion receptor
  • Ly-24
  • phagocytic glycoprotein 1
  • PGP-I
  • hermes antigen
  • hyaluronate receptor

Statements

molecular function
protein binding
determination method or standard
IPI
6 references
retrieved
14 February 2019
stated in
A novel ligand for CD44 is serglycin, a hematopoietic cell lineage-specific proteoglycan. Possible involvement in lymphoid cell adherence and activation
GOA
curator
UniProt
UniProt protein ID
P15379
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379
determination method or standard
IPI
retrieved
14 February 2019
stated in
Galectin-9-CD44 interaction enhances stability and function of adaptive regulatory T cells
GOA
curator
UniProt
UniProt protein ID
P15379
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379
determination method or standard
IPI
retrieved
14 February 2019
stated in
Ezrin/radixin/moesin (ERM) proteins bind to a positively charged amino acid cluster in the juxta-membrane cytoplasmic domain of CD44, CD43, and ICAM-2
GOA
curator
UniProt
UniProt protein ID
P15379
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379
determination method or standard
IPI
retrieved
14 February 2019
stated in
Galectin-9-CD44 interaction enhances stability and function of adaptive regulatory T cells
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379
determination method or standard
IPI
retrieved
14 February 2019
stated in
The PHCCEx domain of Tiam1/2 is a novel protein- and membrane-binding module
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379
determination method or standard
IPI
retrieved
14 February 2019
stated in
Macrophage migration inhibitory factor induces B cell survival by activation of a CD74-CD44 receptor complex
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379
determination method or standard
IPI
cell component
external side of plasma membrane
determination method or standard
IDA
29 references
retrieved
14 February 2019
stated in
The BCL2A1 gene as a pre-T cell receptor-induced regulator of thymocyte survival
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379
determination method or standard
IDA
retrieved
14 February 2019
stated in
Interleukin-2 receptor α chain regulates the size and content of the peripheral lymphoid compartment
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379
determination method or standard
IDA
retrieved
14 February 2019
stated in
Accessory protein-like is essential for IL-18-mediated signaling
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379
determination method or standard
IDA
retrieved
14 February 2019
stated in
CD24 expression on T cells is required for optimal T cell proliferation in lymphopenic host
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379
determination method or standard
IDA
retrieved
14 February 2019
stated in
The transcription factor E4BP4 regulates the production of IL-10 and IL-13 in CD4+ T cells
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379
determination method or standard
IDA
retrieved
14 February 2019
stated in
CDK6 kinase activity is required for thymocyte development
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379
determination method or standard
IDA
retrieved
14 February 2019
stated in
GATA-3 is required for early T lineage progenitor development
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379
determination method or standard
IDA
retrieved
14 February 2019
stated in
The monoclonal antibody TER-119 recognizes a molecule associated with glycophorin A and specifically marks the late stages of murine erythroid lineage
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379
determination method or standard
IDA
retrieved
14 February 2019
stated in
T lymphocytes amplify the anabolic activity of parathyroid hormone through Wnt10b signaling
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379
determination method or standard
IDA
retrieved
14 February 2019
stated in
Cellular mechanisms of fatal early-onset autoimmunity in mice with the T cell-specific targeting of transforming growth factor-beta receptor
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379
determination method or standard
IDA
retrieved
14 February 2019
stated in
Where CD4+CD25+ T reg cells impinge on autoimmune diabetes
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379
determination method or standard
IDA
retrieved
14 February 2019
stated in
CD1d1 mutant mice are deficient in natural T cells that promptly produce IL-4
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379
determination method or standard
IDA
retrieved
14 February 2019
stated in
How defects in central tolerance impinge on a deficiency in regulatory T cells
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379
determination method or standard
IDA
retrieved
14 February 2019
stated in
Foxn1 regulates lineage progression in cortical and medullary thymic epithelial cells but is dispensable for medullary sublineage divergence
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379
determination method or standard
IDA
retrieved
14 February 2019
stated in
miR669a and miR669q prevent skeletal muscle differentiation in postnatal cardiac progenitors
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379
determination method or standard
IDA
retrieved
14 February 2019
stated in
Impaired IgG-dependent anaphylaxis and Arthus reaction in Fc gamma RIII (CD16) deficient mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379
determination method or standard
IDA
retrieved
14 February 2019
stated in
GATA-3 regulates the development and function of invariant NKT cells
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379
determination method or standard
IDA
retrieved
14 February 2019
stated in
Stat5 is required for IL-2-induced cell cycle progression of peripheral T cells
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379
determination method or standard
IDA
retrieved
14 February 2019
stated in
A novel role of CD30/CD30 ligand signaling in the generation of long-lived memory CD8+ T cells
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379
determination method or standard
IDA
retrieved
14 February 2019
stated in
E proteins are required to activate germline transcription of the TCR Vbeta8.2 gene
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379
determination method or standard
IDA
retrieved
14 February 2019
stated in
STAT5 is required for thymopoiesis in a development stage-specific manner
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379
determination method or standard
IDA
retrieved
14 February 2019
stated in
Cutting edge: Toll-like receptor signaling in macrophages induces ligands for the NKG2D receptor
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379
determination method or standard
IDA
retrieved
14 February 2019
stated in
CD1 recognition by mouse NK1+ T lymphocytes
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379
determination method or standard
IDA
retrieved
14 February 2019
stated in
Sox6 is necessary for efficient erythropoiesis in adult mice under physiological and anemia-induced stress conditions
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379
determination method or standard
IDA
retrieved
14 February 2019
stated in
Mac-1 (CD11b/CD18) and CD45 mediate the adhesion of hematopoietic progenitor cells to stromal cell elements via recognition of stromal heparan sulfate
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379
determination method or standard
IDA
retrieved
14 February 2019
stated in
Successful elimination of memory-type CD8+ T cell subsets by the administration of anti-Gr-1 monoclonal antibody in vivo
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379
determination method or standard
IDA
retrieved
14 February 2019
stated in
Reversible defects in natural killer and memory CD8 T cell lineages in interleukin 15-deficient mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379
determination method or standard
IDA
retrieved
14 February 2019
stated in
Increased Foxp3(+) CD4(+) regulatory T cells with intact suppressive activity but altered cellular localization in murine lupus
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379
determination method or standard
IDA
retrieved
14 February 2019
stated in
Requirement for p38alpha in erythropoietin expression: a role for stress kinases in erythropoiesis
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15379
determination method or standard
IDA
biological process

Identifiers

PDB structure ID
 
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