Zw10 kinetochore protein (Q21125070)

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mammalian protein found in Homo sapiens

centromere/kinetochore protein zw10 homolog
ZW10
zeste white 10 homolog
ZW10, kinetochore associated, homolog
ZW10 homolog, centromere/kinetochore protein

Language	Label	Description	Also known as
English	Zw10 kinetochore protein	mammalian protein found in Homo sapiens	centromere/kinetochore protein zw10 homolog ZW10 zeste white 10 homolog ZW10, kinetochore associated, homolog ZW10 homolog, centromere/kinetochore protein

Statements

1 reference

13 November 2019

UniProt protein ID

RZZ complex, subunit Zw10

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O43264

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

centromeric DNA binding

determination method or standard

1 reference

8 April 2019

ZW10 helps recruit dynactin and dynein to the kinetochore

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43264

determination method or standard

protein binding

determination method or standard

12 references

8 April 2019

Human Zw10 and ROD are mitotic checkpoint proteins that bind to kinetochores

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43264

determination method or standard

8 April 2019

Involvement of a novel Q-SNARE, D12, in quality control of the endomembrane system

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43264

determination method or standard

8 April 2019

Zwilch, a new component of the ZW10/ROD complex required for kinetochore functions

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43264

determination method or standard

8 April 2019

RINT-1 regulates the localization and entry of ZW10 to the syntaxin 18 complex

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43264

determination method or standard

8 April 2019

Mitotic control of kinetochore-associated dynein and spindle orientation by human Spindly

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43264

determination method or standard

8 April 2019

ZW10 links mitotic checkpoint signaling to the structural kinetochore.

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43264

determination method or standard

8 April 2019

Hec1 sequentially recruits Zwint-1 and ZW10 to kinetochores for faithful chromosome segregation and spindle checkpoint control

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43264

determination method or standard

8 April 2019

Structural analysis of the RZZ complex reveals common ancestry with multisubunit vesicle tethering machinery

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43264

determination method or standard

8 April 2019

PtdIns(3)P-bound UVRAG coordinates Golgi-ER retrograde and Atg9 transport by differential interactions with the ER tether and the beclin 1 complex

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43264

determination method or standard

8 April 2019

Implication of ZW10 in membrane trafficking between the endoplasmic reticulum and Golgi

HUGO Gene Nomenclature Committee

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43264

determination method or standard

8 April 2019

Human Zwint-1 specifies localization of Zeste White 10 to kinetochores and is essential for mitotic checkpoint signaling

HUGO Gene Nomenclature Committee

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43264

determination method or standard

8 April 2019

Involvement of BNIP1 in apoptosis and endoplasmic reticulum membrane fusion

HUGO Gene Nomenclature Committee

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43264

determination method or standard

determination method or standard

1 reference

8 April 2019

Human Zw10 and ROD are mitotic checkpoint proteins that bind to kinetochores

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43264

determination method or standard

kinetochore microtubule

determination method or standard

1 reference

8 April 2019

Human Zw10 and ROD are mitotic checkpoint proteins that bind to kinetochores

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43264

determination method or standard

endoplasmic reticulum membrane

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43264

determination method or standard

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43264

determination method or standard

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43264

determination method or standard

determination method or standard

1 reference

17 October 2017

Structural analysis of the RZZ complex reveals common ancestry with multisubunit vesicle tethering machinery

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=O43264&geneProductId=UniProtKB:O43264

determination method or standard

Dsl1/NZR complex

determination method or standard

1 reference

8 April 2019

Structural analysis of the RZZ complex reveals common ancestry with multisubunit vesicle tethering machinery

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43264

determination method or standard

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43264

determination method or standard

determination method or standard

5 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43264

determination method or standard

8 April 2019

Mitotic control of kinetochore-associated dynein and spindle orientation by human Spindly

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43264

determination method or standard

8 April 2019

Dynein light intermediate chain 1 is required for progress through the spindle assembly checkpoint

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43264

determination method or standard

8 April 2019

Human Zwint-1 specifies localization of Zeste White 10 to kinetochores and is essential for mitotic checkpoint signaling

HUGO Gene Nomenclature Committee

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43264

determination method or standard

8 April 2019

Specification of kinetochore-forming chromatin by the histone H3 variant CENP-A

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43264

determination method or standard

endoplasmic reticulum

determination method or standard

3 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43264

determination method or standard

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43264

determination method or standard

8 April 2019

Implication of ZW10 in membrane trafficking between the endoplasmic reticulum and Golgi

HUGO Gene Nomenclature Committee

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43264

determination method or standard

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43264

determination method or standard

biological process

Golgi organization

determination method or standard

mitotic cell cycle checkpoint signaling

determination method or standard

1 reference

8 April 2019

Human Zw10 and ROD are mitotic checkpoint proteins that bind to kinetochores

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43264

determination method or standard

mitotic spindle assembly checkpoint signaling

determination method or standard

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43264

determination method or standard

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43264

determination method or standard

endoplasmic reticulum to Golgi vesicle-mediated transport

determination method or standard

1 reference

17 October 2017

Implication of ZW10 in membrane trafficking between the endoplasmic reticulum and Golgi

HUGO Gene Nomenclature Committee

http://www.ebi.ac.uk/QuickGO/annotations?protein=O43264&geneProductId=UniProtKB:O43264

determination method or standard

establishment of mitotic spindle orientation

determination method or standard

1 reference

8 April 2019

Mitotic control of kinetochore-associated dynein and spindle orientation by human Spindly

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43264

determination method or standard

mitotic sister chromatid segregation

determination method or standard

1 reference

8 April 2019

Human Zw10 and ROD are mitotic checkpoint proteins that bind to kinetochores

HUGO Gene Nomenclature Committee

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43264

determination method or standard

protein transport

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43264

determination method or standard

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43264

determination method or standard

mitotic metaphase plate congression

determination method or standard

1 reference

8 April 2019

Mitotic control of kinetochore-associated dynein and spindle orientation by human Spindly

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43264

determination method or standard

regulation of exit from mitosis

determination method or standard

1 reference

8 April 2019

Human Zw10 and ROD are mitotic checkpoint proteins that bind to kinetochores

HUGO Gene Nomenclature Committee

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43264

determination method or standard

protein localization to kinetochore

determination method or standard

1 reference

8 April 2019

Mitotic control of kinetochore-associated dynein and spindle orientation by human Spindly

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43264

determination method or standard

vesicle-mediated transport

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43264

determination method or standard

sister chromatid cohesion

determination method or standard

1 reference

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=O43264&geneProductId=UniProtKB:O43264

determination method or standard

retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43264

determination method or standard

determination method or standard

1 reference

8 April 2019

Conservation of the centromere/kinetochore protein ZW10

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43264

determination method or standard

mitotic cell cycle

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43264

determination method or standard

determination method or standard

1 reference

17 October 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=O43264&geneProductId=UniProtKB:O43264

determination method or standard

endoplasmic reticulum to Golgi vesicle-mediated transport

determination method or standard

protein-containing complex assembly

determination method or standard

1 reference

8 April 2019

Human Zw10 and ROD are mitotic checkpoint proteins that bind to kinetochores

HUGO Gene Nomenclature Committee

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43264

determination method or standard

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000200135

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000200135

ENSP00000440879

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000440879

ENSP00000439197

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000439197

Sitelinks

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Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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