Programmed cell death 5 (Q21119690)

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mammalian protein found in Homo sapiens

TFAR19 novel apoptosis-related
TF-1 cell apoptosis-related protein 19
Protein TFAR19
PDCD5
TF1 cell apoptosis-related gene 19
programmed cell death protein 5

Language	Label	Description	Also known as
English	Programmed cell death 5	mammalian protein found in Homo sapiens	TFAR19 novel apoptosis-related TF-1 cell apoptosis-related protein 19 Protein TFAR19 PDCD5 TF1 cell apoptosis-related gene 19 programmed cell death protein 5

Statements

1 reference

13 November 2019

UniProt protein ID

PDCD5-like superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O14737

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O14737

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14737

determination method or standard

heparin binding

determination method or standard

1 reference

8 April 2019

Studies on interactions of programmed cell death 5 (PDCD5) and its related peptides with heparin by capillary zone electrophoresis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14737

determination method or standard

protein binding

determination method or standard

2 references

acetyltransferase activator activity

determination method or standard

1 reference

8 April 2019

PDCD5 negatively regulates autoimmunity by upregulating FOXP3(+) regulatory T cells and suppressing Th17 and Th1 responses

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14737

determination method or standard

beta-tubulin binding

determination method or standard

1 reference

8 April 2019

Programmed cell death protein 5 interacts with the cytosolic chaperonin containing tailless complex polypeptide 1 (CCT) to regulate β-tubulin folding

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14737

determination method or standard

determination method or standard

1 reference

26 September 2017

Dynamic proteomics in individual human cells uncovers widespread cell-cycle dependence of nuclear proteins

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=O14737&geneProductId=UniProtKB:O14737

determination method or standard

extracellular exosome

determination method or standard

1 reference

26 September 2017

MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=O14737&geneProductId=UniProtKB:O14737

determination method or standard

determination method or standard

1 reference

26 September 2017

PDCD5 negatively regulates autoimmunity by upregulating FOXP3(+) regulatory T cells and suppressing Th17 and Th1 responses

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=O14737&geneProductId=UniProtKB:O14737

determination method or standard

determination method or standard

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14737

determination method or standard

determination method or standard

determination method or standard

1 reference

8 April 2019

Dynamic proteomics in individual human cells uncovers widespread cell-cycle dependence of nuclear proteins

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14737

determination method or standard

extracellular exosome

determination method or standard

1 reference

8 April 2019

MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14737

determination method or standard

biological process

cellular response to transforming growth factor beta stimulus

determination method or standard

1 reference

8 April 2019

PDCD5 negatively regulates autoimmunity by upregulating FOXP3(+) regulatory T cells and suppressing Th17 and Th1 responses

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14737

determination method or standard

negative regulation of chaperone-mediated protein folding

determination method or standard

1 reference

8 April 2019

Programmed cell death protein 5 interacts with the cytosolic chaperonin containing tailless complex polypeptide 1 (CCT) to regulate β-tubulin folding

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14737

determination method or standard

positive regulation of release of cytochrome c from mitochondria

determination method or standard

1 reference

8 April 2019

Short interfering RNA against the PDCD5 attenuates cell apoptosis and caspase-3 activity induced by Bax overexpression

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14737

determination method or standard

apoptotic process

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14737

determination method or standard

positive regulation of cysteine-type endopeptidase activity involved in apoptotic process

determination method or standard

1 reference

8 April 2019

Short interfering RNA against the PDCD5 attenuates cell apoptosis and caspase-3 activity induced by Bax overexpression

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14737

determination method or standard

positive regulation of gene expression

determination method or standard

1 reference

8 April 2019

PDCD5 negatively regulates autoimmunity by upregulating FOXP3(+) regulatory T cells and suppressing Th17 and Th1 responses

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14737

determination method or standard

positive regulation of protein insertion into mitochondrial outer membrane

determination method or standard

1 reference

8 April 2019

Short interfering RNA against the PDCD5 attenuates cell apoptosis and caspase-3 activity induced by Bax overexpression

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14737

determination method or standard

negative regulation of cell population proliferation

determination method or standard

1 reference

8 April 2019

Short interfering RNA against the PDCD5 attenuates cell apoptosis and caspase-3 activity induced by Bax overexpression

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14737

determination method or standard

positive regulation of apoptotic process

determination method or standard

1 reference

8 April 2019

TFAR19, a novel apoptosis-related gene cloned from human leukemia cell line TF-1, could enhance apoptosis of some tumor cells induced by growth factor withdrawal

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14737

determination method or standard

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000466214

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000466214

ENSP00000476525

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000476525

ENSP00000221784

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000221784

ENSP00000368620

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000368620

ENSP00000467737

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000467737

ENSP00000468741

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000468741

PDB structure ID

1 reference

UniProt protein ID

20 March 2016

language of work or name

1 reference

UniProt protein ID

20 March 2016

language of work or name

1 reference

UniProt protein ID

20 March 2016

language of work or name

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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