5-hydroxytryptamine receptor 1F (Q21115052)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P30939

GPCR, rhodopsin-like, 7TM, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

signal transducer activity

http://www.ebi.ac.uk/QuickGO/annotations?protein=P30939&geneProductId=UniProtKB:P30939

1 reference

31 October 2017

serotonin binding

1 reference

8 April 2019

Cloning of another human serotonin receptor (5-HT1F): a fifth 5-HT1 receptor subtype coupled to the inhibition of adenylate cyclase

GOA

curator

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30939

G protein-coupled serotonin receptor activity

Cloning of another human serotonin receptor (5-HT1F): a fifth 5-HT1 receptor subtype coupled to the inhibition of adenylate cyclase

4 references

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P30939&geneProductId=UniProtKB:P30939

5 June 2018

Toward selective drug development for the human 5-hydroxytryptamine 1E receptor: a comparison of 5-hydroxytryptamine 1E and 1F receptor structure-affinity relationships

http://www.ebi.ac.uk/QuickGO/annotations?protein=P30939&geneProductId=UniProtKB:P30939

http://www.ebi.ac.uk/QuickGO/annotations?protein=P30939&geneProductId=UniProtKB:P30939

5 June 2018

5 June 2018

Cloning of another human serotonin receptor (5-HT1F): a fifth 5-HT1 receptor subtype coupled to the inhibition of adenylate cyclase

GOA

curator

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P30939&geneProductId=UniProtKB:P30939

neurotransmitter receptor activity

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30939

G protein-coupled receptor activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30939

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30939

8 April 2019

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30939

G protein-coupled serotonin receptor activity

Cloning of another human serotonin receptor (5-HT1F): a fifth 5-HT1 receptor subtype coupled to the inhibition of adenylate cyclase

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30939

8 April 2019

Toward selective drug development for the human 5-hydroxytryptamine 1E receptor: a comparison of 5-hydroxytryptamine 1E and 1F receptor structure-affinity relationships

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30939

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30939

8 April 2019

8 April 2019

Cloning of another human serotonin receptor (5-HT1F): a fifth 5-HT1 receptor subtype coupled to the inhibition of adenylate cyclase

GOA

curator

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30939

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30939

integral component of plasma membrane

cell component

Cloning of another human serotonin receptor (5-HT1F): a fifth 5-HT1 receptor subtype coupled to the inhibition of adenylate cyclase

3 references

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P30939&geneProductId=UniProtKB:P30939

5 June 2018

Toward selective drug development for the human 5-hydroxytryptamine 1E receptor: a comparison of 5-hydroxytryptamine 1E and 1F receptor structure-affinity relationships

http://www.ebi.ac.uk/QuickGO/annotations?protein=P30939&geneProductId=UniProtKB:P30939

http://www.ebi.ac.uk/QuickGO/annotations?protein=P30939&geneProductId=UniProtKB:P30939

5 June 2018

membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30939

1 reference

8 April 2019

integral component of plasma membrane

Cloning of another human serotonin receptor (5-HT1F): a fifth 5-HT1 receptor subtype coupled to the inhibition of adenylate cyclase

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30939

8 April 2019

Toward selective drug development for the human 5-hydroxytryptamine 1E receptor: a comparison of 5-hydroxytryptamine 1E and 1F receptor structure-affinity relationships

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30939

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30939

8 April 2019

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30939

dendrite

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30939

G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger

biological process

1 reference

5 June 2018

Cloning of another human serotonin receptor (5-HT1F): a fifth 5-HT1 receptor subtype coupled to the inhibition of adenylate cyclase

http://www.ebi.ac.uk/QuickGO/annotations?protein=P30939&geneProductId=UniProtKB:P30939

adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway

IMP

1 reference

8 April 2019

Toward selective drug development for the human 5-hydroxytryptamine 1E receptor: a comparison of 5-hydroxytryptamine 1E and 1F receptor structure-affinity relationships

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30939

IMP

signal transduction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30939

1 reference

8 April 2019

chemical synaptic transmission

1 reference

5 June 2018

Cloning of another human serotonin receptor (5-HT1F): a fifth 5-HT1 receptor subtype coupled to the inhibition of adenylate cyclase

http://www.ebi.ac.uk/QuickGO/annotations?protein=P30939&geneProductId=UniProtKB:P30939

G protein-coupled serotonin receptor signaling pathway

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P30939

G protein-coupled receptor signaling pathway

G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger

chemical synaptic transmission

physically interacts with

1 reference

218

17 August 2016

5-carboxamidotryptamine

1 reference

4

17 August 2016

1 reference

5

N,N-dimethyl-5-methoxytryptamine

17 August 2016

1 reference

145

17 August 2016

1 reference

107

(+/-)-8-hydroxy-2-(di-N-propylamino)tetralin

17 August 2016

1 reference

7

17 August 2016

1 reference

152

17 August 2016

1 reference

3927

17 August 2016

1 reference

38

17 August 2016

1 reference

121

4-iodo-2,5-dimethoxyphenylisopropylamine

17 August 2016

1 reference

147

17 August 2016

1 reference

39

17 August 2016

1 reference

40

17 August 2016

1 reference

149

17 August 2016

1 reference

3928

17 August 2016

2 references

20

17 August 2016

151

17 August 2016

1 reference

45

17 August 2016

1 reference

47

17 August 2016

1 reference

50

17 August 2016

1 reference

51

17 August 2016

1 reference

54

1-(3-trifluoromethylphenyl)piperazine

17 August 2016

1 reference

115

17 August 2016

1 reference

125

17 August 2016

1 reference

57

17 August 2016

1 reference

60

17 August 2016

1 reference

10

17 August 2016

1 reference

14

17 August 2016

1 reference

73

17 August 2016

1 reference

3

17 August 2016

1 reference

133

17 August 2016

1 reference

89

17 August 2016

1 reference

150

17 August 2016

1 reference

134

17 August 2016

1 reference

96

17 August 2016

1 reference

98

17 August 2016

1 reference

102

object of statement has role

17 August 2016

zimeldine

antagonist

1 reference

Open Targets Platform

14 August 2023

https://platform.opentargets.org/drug/CHEMBL37744

has part(s)

GPCR, rhodopsin-like, 7TM

1 reference

InterPro Release 71.0